DACB - ECOLI - GREMLIN Contacts

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DACB - D-alanyl-D-alanine carboxypeptidase DacB

UniProt:	P24228	Sequences: MRFSRFIIGLTSCIAFSVQAANVDEYITQLPAGANLALMVQKVGASAPAIDYHSQQMALPASTQKVITALAALIQLGPDFRFTTTLETKGNVENGVLKGDLVARFGADPTLKRQDIRNMVATLKKSGVNQIDGNVLIDTSIFASHDKAPGWPWNDMTQCFSAPPAAAIVDRNCFSVSLYSAPKPGDMAFIRVASYYPVTMFSQVRTLPRGSAEAQYCELDVVPGDLNRFTLTGCLPQRSEPLPLAFAVQDGASYAGAILKDELKQAGITWSGTLLRQTQVNEPGTVVASKQSAPLHDLLKIMLKKSDNMIADTVFRMIGHARFNVPGTWRAGSDAVRQILRQQAGVDIGNTIIADGSGLSRHNLIAPATMMQVLQYIAQHDNELNFISMLPLAGYDGSLQYRAGLHQAGVDGKVSAKTGSLQGVYNLAGFITTASGQRMAFVQYLSGYAVEPADQRNRRIPLVRFESRLYKDIYQNN	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10202
Length:	477 (438)
Sequences:	1508 (1209)
Seq/√Len:	57.8

ECOLI - DACB
BACSU - DACC

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
63_T	428_A	5.362	1.00
89_K	100_D	5.117	1.00
303_L	389_M	4.827	1.00
37_A	367_P	4.823	1.00
51_D	54_S	3.963	1.00
42_K	437_Q	3.884	1.00
304_K	396_D	3.788	1.00
58_A	367_P	3.735	1.00
37_A	58_A	3.569	1.00
188_A	204_V	3.357	1.00
69_A	302_M	3.224	1.00
119_M	288_A	3.184	1.00
55_Q	368_A	3.053	1.00
43_V	440_A	2.994	1.00
428_A	442_V	2.970	1.00
90_G	97_L	2.848	1.00
82_F	317_M	2.847	1.00
110_T	298_L	2.821	1.00
40_V	439_M	2.776	1.00
315_F	332_G	2.736	1.00
207_L	211_S	2.698	1.00
63_T	370_M	2.629	1.00
69_A	303_L	2.535	1.00
39_M	371_M	2.525	1.00
98_K	132_D	2.488	1.00
168_I	313_T	2.488	1.00
433_T	439_M	2.456	1.00
391_P	416_A	2.446	1.00
63_T	442_V	2.422	1.00
106_G	141_I	2.404	1.00
426_N	444_Y	2.362	1.00
399_L	416_A	2.359	1.00
281_N	284_G	2.274	1.00
134_N	272_G	2.273	1.00
148_A	151_W	2.195	1.00
416_A	427_L	2.190	1.00
88_T	287_V	2.157	1.00
416_A	441_F	2.146	1.00
87_E	104_R	2.142	1.00
370_M	444_Y	2.134	1.00
123_L	126_S	2.127	1.00
371_M	440_A	2.095	1.00
83_T	291_Q	2.089	1.00
374_L	430_F	2.054	1.00
66_V	373_V	2.046	1.00
130_Q	271_S	2.000	1.00
35_N	53_H	1.997	1.00
93_E	98_K	1.989	1.00
171_R	307_D	1.975	1.00
371_M	442_V	1.969	1.00
67_I	373_V	1.966	1.00
414_V	441_F	1.954	1.00
105_F	167_A	1.950	1.00
169_V	258_I	1.950	1.00
367_P	444_Y	1.935	1.00
70_L	377_I	1.929	1.00
100_D	133_G	1.929	1.00
89_K	102_V	1.856	1.00
100_D	134_N	1.845	1.00
69_A	299_L	1.839	1.00
86_L	119_M	1.834	0.99
286_V	289_S	1.824	0.99
402_R	460_I	1.815	0.99
66_V	390_L	1.765	0.99
67_I	365_I	1.761	0.99
432_T	438_R	1.754	0.99
85_T	104_R	1.751	0.99
120_V	259_L	1.749	0.99
90_G	99_G	1.741	0.99
142_F	317_M	1.730	0.99
302_M	311_A	1.729	0.99
115_D	290_K	1.721	0.99
99_G	133_G	1.719	0.99
102_V	281_N	1.718	0.99
53_H	56_Q	1.712	0.99
39_M	48_P	1.709	0.99
392_L	396_D	1.700	0.99
92_V	95_G	1.683	0.99
141_I	320_H	1.659	0.99
120_V	266_A	1.652	0.99
408_A	464_R	1.642	0.99
399_L	427_L	1.640	0.99
375_Q	440_A	1.636	0.99
130_Q	269_T	1.632	0.99
41_Q	371_M	1.626	0.99
86_L	123_L	1.620	0.99
42_K	45_A	1.616	0.99
103_A	255_A	1.610	0.99
168_I	309_M	1.603	0.99
408_A	411_D	1.591	0.99
121_A	266_A	1.584	0.98
124_K	129_N	1.582	0.98
116_I	169_V	1.580	0.98
386_F	430_F	1.576	0.98
180_S	206_T	1.576	0.98
418_T	427_L	1.568	0.98
319_G	332_G	1.555	0.98
92_V	97_L	1.548	0.98
414_V	463_V	1.538	0.98
123_L	268_I	1.531	0.98
128_V	287_V	1.526	0.98
181_A	206_T	1.502	0.98
87_E	286_V	1.501	0.98
103_A	135_V	1.498	0.98
48_P	51_D	1.492	0.98
56_Q	367_P	1.491	0.98
87_E	284_G	1.473	0.98
67_I	370_M	1.469	0.98
443_Q	459_R	1.458	0.97
96_V	130_Q	1.455	0.97
139_T	252_A	1.433	0.97
427_L	463_V	1.431	0.97
181_A	186_D	1.426	0.97
302_M	310_I	1.421	0.97
188_A	231_L	1.408	0.97
151_W	355_D	1.406	0.97
425_Y	459_R	1.395	0.97
315_F	356_G	1.393	0.97
204_V	231_L	1.392	0.97
185_G	206_T	1.381	0.96
83_T	289_S	1.357	0.96
64_Q	363_N	1.354	0.96
263_L	268_I	1.354	0.96
92_V	128_V	1.352	0.96
293_A	297_D	1.339	0.96
414_V	431_I	1.334	0.96
376_Y	380_H	1.326	0.95
383_E	387_I	1.307	0.95
139_T	165_A	1.303	0.95
326_P	331_A	1.297	0.95
75_Q	318_I	1.295	0.95
124_K	266_A	1.293	0.95
374_L	428_A	1.291	0.95
315_F	333_S	1.287	0.95
159_C	173_C	1.281	0.94
123_L	128_V	1.274	0.94
134_N	276_R	1.258	0.94
85_T	106_G	1.256	0.94
378_A	438_R	1.255	0.94
176_V	231_L	1.251	0.94
74_I	380_H	1.249	0.94
387_I	415_S	1.245	0.94
137_I	256_G	1.241	0.94
319_G	335_A	1.234	0.93
413_K	432_T	1.231	0.93
112_K	115_D	1.226	0.93
312_D	357_S	1.220	0.93
377_I	382_N	1.217	0.93
81_R	291_Q	1.214	0.93
150_G	362_H	1.201	0.92
110_T	310_I	1.197	0.92
307_D	310_I	1.195	0.92
301_I	305_K	1.188	0.92
217_C	221_V	1.177	0.92
124_K	268_I	1.159	0.91
43_V	378_A	1.157	0.91
43_V	375_Q	1.153	0.91
63_T	426_N	1.137	0.90
73_L	389_M	1.136	0.90
123_L	287_V	1.134	0.90
42_K	47_A	1.131	0.90
36_L	445_L	1.125	0.90
49_A	439_M	1.122	0.89
75_Q	339_I	1.121	0.89
370_M	428_A	1.119	0.89
96_V	99_G	1.116	0.89
111_L	116_I	1.112	0.89
59_L	364_L	1.107	0.89
138_D	141_I	1.107	0.89
160_F	359_L	1.107	0.89
178_L	190_I	1.103	0.89
35_N	447_G	1.103	0.89
312_D	329_W	1.102	0.89
38_L	443_Q	1.092	0.88
171_R	310_I	1.090	0.88
309_M	313_T	1.083	0.88
138_D	142_F	1.083	0.88
361_R	421_L	1.082	0.88
23_V	462_L	1.080	0.88
315_F	336_V	1.079	0.88
71_A	318_I	1.078	0.88
410_V	431_I	1.078	0.88
303_L	390_L	1.077	0.87
104_R	138_D	1.073	0.87
217_C	231_L	1.067	0.87
250_D	253_S	1.067	0.87
80_F	317_M	1.063	0.87
97_L	133_G	1.060	0.87
41_Q	375_Q	1.057	0.86
460_I	463_V	1.053	0.86
188_A	235_L	1.048	0.86
312_D	355_D	1.042	0.86
151_W	359_L	1.042	0.86
85_T	286_V	1.041	0.86
39_M	440_A	1.029	0.85
67_I	353_I	1.021	0.85
137_I	167_A	1.020	0.84
74_I	339_I	1.020	0.84
420_S	425_Y	1.018	0.84
346_V	373_V	1.015	0.84
73_L	78_P	1.014	0.84
213_E	236_P	1.007	0.84
148_A	152_P	1.006	0.84
97_L	128_V	1.005	0.84
393_A	399_L	1.004	0.84
257_A	261_D	1.003	0.83
99_G	128_V	1.002	0.83
319_G	327_G	0.999	0.83
119_M	290_K	0.993	0.83
132_D	271_S	0.990	0.83
165_A	247_A	0.989	0.83
299_L	314_V	0.988	0.83
72_A	76_L	0.981	0.82
458_R	462_L	0.979	0.82
304_K	391_P	0.977	0.82
22_N	465_F	0.975	0.82
106_G	313_T	0.975	0.82
254_Y	258_I	0.973	0.82
153_W	355_D	0.973	0.82
88_T	97_L	0.973	0.82
119_M	123_L	0.966	0.81
180_S	240_E	0.966	0.81
35_N	56_Q	0.963	0.81
77_G	292_S	0.963	0.81
201_F	228_R	0.955	0.80
430_F	446_S	0.954	0.80
410_V	463_V	0.953	0.80
151_W	312_D	0.952	0.80
390_L	399_L	0.950	0.80
152_P	362_H	0.949	0.80
207_L	234_C	0.945	0.80
175_S	245_A	0.945	0.80
117_R	265_Q	0.942	0.79
319_G	331_A	0.935	0.79
105_F	259_L	0.933	0.79
148_A	161_S	0.932	0.79
172_N	383_E	0.929	0.78
152_P	161_S	0.924	0.78
116_I	262_E	0.922	0.78
148_A	153_W	0.921	0.78
299_L	303_L	0.919	0.78
117_R	262_E	0.914	0.77
20_A	24_D	0.911	0.77
299_L	389_M	0.909	0.77
335_A	338_Q	0.909	0.77
350_N	369_T	0.908	0.77
316_R	329_W	0.907	0.77
154_N	354_A	0.904	0.77
348_I	365_I	0.903	0.76
153_W	364_L	0.903	0.76
164_P	313_T	0.900	0.76
394_G	397_G	0.899	0.76
24_D	50_I	0.897	0.76
333_S	353_I	0.895	0.76
103_A	259_L	0.894	0.76
138_D	166_A	0.893	0.76
316_R	327_G	0.893	0.76
148_A	154_N	0.891	0.75
394_G	398_S	0.888	0.75
207_L	236_P	0.887	0.75
348_I	351_T	0.887	0.75
85_T	289_S	0.882	0.75
134_N	273_T	0.882	0.75
304_K	392_L	0.881	0.75
41_Q	440_A	0.879	0.74
88_T	91_N	0.878	0.74
51_D	368_A	0.876	0.74
90_G	102_V	0.872	0.74
112_K	171_R	0.872	0.74
393_A	414_V	0.867	0.73
62_S	65_K	0.867	0.73
431_I	463_V	0.865	0.73
117_R	266_A	0.865	0.73
176_V	229_F	0.864	0.73
420_S	424_V	0.856	0.73
344_A	376_Y	0.855	0.72
91_N	97_L	0.853	0.72
424_V	446_S	0.850	0.72
48_P	52_Y	0.848	0.72
339_I	344_A	0.848	0.72
86_L	128_V	0.845	0.72
143_A	316_R	0.844	0.71
59_L	361_R	0.844	0.71
168_I	172_N	0.843	0.71
210_G	238_R	0.842	0.71
95_G	99_G	0.841	0.71
366_A	369_T	0.838	0.71
361_R	364_L	0.837	0.71
39_M	51_D	0.834	0.71
357_S	363_N	0.831	0.70
151_W	161_S	0.824	0.70
104_R	284_G	0.816	0.69
59_L	446_S	0.815	0.69
247_A	420_S	0.811	0.68
165_A	168_I	0.806	0.68
371_M	375_Q	0.801	0.67
142_F	166_A	0.798	0.67
86_L	259_L	0.798	0.67
61_A	359_L	0.797	0.67
219_L	246_F	0.795	0.67
370_M	442_V	0.795	0.67
169_V	255_A	0.793	0.67
340_L	346_V	0.791	0.66
97_L	100_D	0.787	0.66
204_V	217_C	0.786	0.66
63_T	444_Y	0.786	0.66
327_G	331_A	0.786	0.66
305_K	310_I	0.783	0.66
102_V	280_V	0.782	0.66
406_H	411_D	0.779	0.65
105_F	137_I	0.778	0.65
427_L	441_F	0.777	0.65
82_F	106_G	0.777	0.65
162_A	254_Y	0.776	0.65
24_D	52_Y	0.775	0.65
355_D	363_N	0.775	0.65
68_T	318_I	0.775	0.65
217_C	234_C	0.771	0.64
221_V	229_F	0.768	0.64
98_K	130_Q	0.767	0.64
35_N	58_A	0.766	0.64
71_A	336_V	0.765	0.64
140_S	279_Q	0.765	0.64
351_T	369_T	0.764	0.64
161_S	355_D	0.763	0.64
401_Y	406_H	0.761	0.63
372_Q	375_Q	0.761	0.63
28_T	264_K	0.760	0.63
230_T	346_V	0.759	0.63
100_D	136_L	0.758	0.63
445_L	459_R	0.757	0.63
68_T	315_F	0.755	0.63
427_L	439_M	0.755	0.63
72_A	100_D	0.754	0.63
171_R	305_K	0.748	0.62
129_N	261_D	0.747	0.62
39_M	54_S	0.744	0.62
91_N	95_G	0.743	0.62
393_A	408_A	0.742	0.61
318_I	336_V	0.741	0.61
80_F	106_G	0.741	0.61
61_A	308_N	0.739	0.61
432_T	436_G	0.737	0.61
26_Y	270_W	0.737	0.61
325_V	331_A	0.736	0.61
391_P	399_L	0.734	0.61
97_L	101_L	0.731	0.60
28_T	343_Q	0.731	0.60
110_T	293_A	0.729	0.60
116_I	119_M	0.728	0.60
402_R	427_L	0.726	0.60
317_M	321_A	0.725	0.60
302_M	307_D	0.725	0.60
381_D	384_L	0.723	0.59
70_L	373_V	0.720	0.59
39_M	368_A	0.716	0.59
107_A	142_F	0.715	0.59
242_L	246_F	0.714	0.59
136_L	154_N	0.714	0.59
122_T	288_A	0.711	0.58
151_W	155_D	0.709	0.58
76_L	317_M	0.708	0.58
163_P	249_Q	0.706	0.58
206_T	235_L	0.705	0.58
394_G	411_D	0.704	0.57
153_W	354_A	0.702	0.57
188_A	206_T	0.701	0.57
427_L	431_I	0.699	0.57
346_V	349_G	0.697	0.57
90_G	133_G	0.696	0.57
327_G	332_G	0.696	0.57
461_P	464_R	0.696	0.57
61_A	306_S	0.694	0.56
229_F	247_A	0.693	0.56
348_I	369_T	0.692	0.56
252_A	346_V	0.692	0.56
155_D	161_S	0.692	0.56
392_L	395_Y	0.691	0.56
179_Y	189_F	0.690	0.56
419_G	429_G	0.688	0.56
126_S	287_V	0.687	0.56
178_L	229_F	0.685	0.55
365_I	370_M	0.684	0.55
340_L	402_R	0.682	0.55
211_S	234_C	0.681	0.55
299_L	378_A	0.679	0.55
316_R	332_G	0.678	0.55
306_S	419_G	0.677	0.55
151_W	363_N	0.676	0.54
415_S	420_S	0.676	0.54
106_G	256_G	0.674	0.54
259_L	348_I	0.674	0.54
262_E	265_Q	0.673	0.54
40_V	268_I	0.671	0.54
304_K	418_T	0.670	0.54
66_V	386_F	0.670	0.54
263_L	270_W	0.669	0.54
161_S	247_A	0.669	0.54
173_C	307_D	0.667	0.53
174_F	246_F	0.667	0.53
49_A	85_T	0.667	0.53
113_R	170_D	0.666	0.53
243_P	444_Y	0.665	0.53
117_R	121_A	0.665	0.53
231_L	295_L	0.664	0.53
118_N	121_A	0.664	0.53
96_V	132_D	0.662	0.53
103_A	119_M	0.662	0.53
131_I	201_F	0.661	0.53
156_M	309_M	0.661	0.53
178_L	303_L	0.660	0.53
150_G	153_W	0.659	0.53
97_L	131_I	0.658	0.52
223_P	249_Q	0.657	0.52
153_W	360_S	0.655	0.52
55_Q	278_T	0.655	0.52
178_L	231_L	0.654	0.52
199_T	228_R	0.653	0.52
73_L	386_F	0.652	0.52
203_Q	230_T	0.652	0.52
42_K	49_A	0.650	0.52
346_V	369_T	0.649	0.51
64_Q	353_I	0.647	0.51
393_A	397_G	0.647	0.51
425_Y	443_Q	0.647	0.51
110_T	292_S	0.645	0.51
334_D	338_Q	0.645	0.51
332_G	335_A	0.644	0.51
75_Q	322_R	0.641	0.51
102_V	284_G	0.641	0.51
77_G	108_D	0.640	0.50
180_S	188_A	0.633	0.50
370_M	373_V	0.632	0.50
306_S	417_K	0.630	0.49
29_Q	44_G	0.630	0.49
461_P	465_F	0.628	0.49
87_E	280_V	0.627	0.49
78_P	265_Q	0.627	0.49
64_Q	365_I	0.626	0.49
201_F	230_T	0.625	0.49
131_I	270_W	0.624	0.49
298_L	313_T	0.623	0.49
126_S	129_N	0.623	0.49
165_A	421_L	0.623	0.49
402_R	418_T	0.623	0.49
202_S	205_R	0.622	0.48
164_P	316_R	0.622	0.48
61_A	160_F	0.621	0.48
66_V	428_A	0.620	0.48
141_I	166_A	0.620	0.48
80_F	321_A	0.619	0.48
203_Q	232_T	0.619	0.48
123_L	135_V	0.617	0.48
87_E	103_A	0.617	0.48
38_L	398_S	0.613	0.47
261_D	264_K	0.613	0.47
58_A	444_Y	0.612	0.47
308_N	419_G	0.612	0.47
42_K	435_S	0.611	0.47
167_A	256_G	0.610	0.47
55_Q	366_A	0.609	0.47
80_F	83_T	0.608	0.47
111_L	412_G	0.608	0.47
335_A	339_I	0.607	0.47
71_A	339_I	0.606	0.47
282_E	365_I	0.604	0.46
174_F	229_F	0.604	0.46
170_D	299_L	0.604	0.46
179_Y	191_R	0.603	0.46
16_F	20_A	0.603	0.46
94_N	401_Y	0.603	0.46
121_A	386_F	0.602	0.46
256_G	274_L	0.602	0.46
39_M	367_P	0.602	0.46
111_L	443_Q	0.601	0.46
294_P	297_D	0.599	0.46
310_I	314_V	0.596	0.46
181_A	184_P	0.596	0.46
202_S	446_S	0.594	0.45
395_Y	412_G	0.594	0.45
308_N	417_K	0.593	0.45
42_K	46_S	0.592	0.45
79_D	203_Q	0.592	0.45
48_P	368_A	0.591	0.45
339_I	376_Y	0.591	0.45
366_A	451_E	0.591	0.45
151_W	156_M	0.590	0.45
166_A	272_G	0.590	0.45
302_M	315_F	0.589	0.45
445_L	448_Y	0.589	0.45
254_Y	460_I	0.588	0.45
184_P	206_T	0.588	0.45
104_R	280_V	0.585	0.44
111_L	255_A	0.584	0.44
114_Q	171_R	0.583	0.44
172_N	307_D	0.583	0.44
416_A	463_V	0.582	0.44
109_P	310_I	0.580	0.44
120_V	263_L	0.580	0.44
158_Q	244_L	0.580	0.44
86_L	122_T	0.580	0.44
70_L	386_F	0.580	0.44
149_P	152_P	0.579	0.44
250_D	257_A	0.579	0.44
200_M	353_I	0.578	0.44
331_A	334_D	0.578	0.44
359_L	421_L	0.577	0.44
178_L	204_V	0.577	0.44
56_Q	388_S	0.576	0.43
73_L	385_N	0.576	0.43
420_S	426_N	0.575	0.43
129_N	318_I	0.575	0.43
317_M	320_H	0.574	0.43
165_A	441_F	0.574	0.43
90_G	96_V	0.573	0.43
385_N	389_M	0.573	0.43
54_S	368_A	0.572	0.43
276_R	346_V	0.572	0.43
318_I	332_G	0.569	0.43
143_A	328_T	0.569	0.43
135_V	424_V	0.569	0.43
152_P	361_R	0.568	0.43
174_F	196_Y	0.568	0.43
399_L	418_T	0.566	0.42
369_T	372_Q	0.566	0.42
82_F	168_I	0.564	0.42
165_A	172_N	0.563	0.42
433_T	436_G	0.563	0.42
431_I	439_M	0.562	0.42
50_I	316_R	0.562	0.42
172_N	363_N	0.561	0.42
311_A	357_S	0.560	0.42
112_K	310_I	0.560	0.42
23_V	54_S	0.560	0.42
159_C	171_R	0.560	0.42
121_A	125_K	0.558	0.41
178_L	217_C	0.558	0.41
99_G	136_L	0.557	0.41
130_Q	435_S	0.556	0.41
385_N	415_S	0.556	0.41
135_V	247_A	0.556	0.41
183_K	420_S	0.556	0.41
198_V	202_S	0.555	0.41
328_T	373_V	0.555	0.41
125_K	407_Q	0.555	0.41
159_C	305_K	0.554	0.41
450_V	453_A	0.554	0.41
189_F	279_Q	0.554	0.41
257_A	276_R	0.554	0.41
459_R	462_L	0.553	0.41
160_F	465_F	0.553	0.41
59_L	421_L	0.552	0.41
410_V	413_K	0.550	0.41
206_T	366_A	0.550	0.41
171_R	301_I	0.549	0.41
448_Y	454_D	0.548	0.40
206_T	237_Q	0.548	0.40
37_A	223_P	0.547	0.40
219_L	336_V	0.547	0.40
174_F	249_Q	0.546	0.40
354_A	363_N	0.546	0.40
81_R	134_N	0.546	0.40
251_G	312_D	0.545	0.40
22_N	31_P	0.545	0.40
312_D	348_I	0.545	0.40
93_E	96_V	0.544	0.40
122_T	125_K	0.543	0.40
416_A	443_Q	0.542	0.40
109_P	359_L	0.542	0.40
296_H	299_L	0.542	0.40
148_A	329_W	0.542	0.40
88_T	123_L	0.541	0.40
411_D	464_R	0.541	0.40
86_L	251_G	0.539	0.39
299_L	382_N	0.539	0.39
70_L	376_Y	0.539	0.39
88_T	122_T	0.539	0.39
312_D	316_R	0.538	0.39
178_L	235_L	0.537	0.39
172_N	251_G	0.536	0.39
296_H	385_N	0.535	0.39
301_I	363_N	0.535	0.39
124_K	386_F	0.534	0.39
19_Q	22_N	0.534	0.39
420_S	448_Y	0.534	0.39
107_A	292_S	0.533	0.39
47_A	78_P	0.533	0.39
339_I	380_H	0.533	0.39
301_I	307_D	0.532	0.39
131_I	268_I	0.531	0.39
113_R	169_V	0.531	0.39
259_L	262_E	0.530	0.39
377_I	380_H	0.529	0.38
101_L	131_I	0.529	0.38
263_L	363_N	0.529	0.38
118_N	136_L	0.529	0.38
398_S	402_R	0.529	0.38
23_V	443_Q	0.528	0.38
120_V	268_I	0.528	0.38
253_S	256_G	0.528	0.38
302_M	314_V	0.527	0.38
332_G	357_S	0.527	0.38
91_N	101_L	0.526	0.38
103_A	240_E	0.526	0.38
297_D	300_K	0.526	0.38
295_L	299_L	0.525	0.38
91_N	98_K	0.525	0.38
304_K	402_R	0.524	0.38
302_M	391_P	0.523	0.38
393_A	410_V	0.523	0.38
57_M	366_A	0.522	0.38
152_P	421_L	0.522	0.38
328_T	332_G	0.521	0.38
36_L	120_V	0.520	0.37
27_I	167_A	0.519	0.37
93_E	186_D	0.518	0.37
173_C	245_A	0.518	0.37
361_R	423_G	0.517	0.37
88_T	285_T	0.517	0.37
111_L	463_V	0.516	0.37
19_Q	27_I	0.515	0.37
82_F	298_L	0.514	0.37
139_T	307_D	0.514	0.37
113_R	258_I	0.513	0.37
139_T	166_A	0.512	0.37
320_H	326_P	0.512	0.37
260_K	274_L	0.512	0.37
95_G	187_M	0.512	0.37
303_L	421_L	0.511	0.37
62_S	306_S	0.511	0.37
367_P	377_I	0.511	0.37
166_A	304_K	0.510	0.36
124_K	273_T	0.510	0.36
47_A	437_Q	0.509	0.36
164_P	353_I	0.508	0.36
319_G	402_R	0.508	0.36
42_K	433_T	0.508	0.36
151_W	357_S	0.508	0.36
421_L	424_V	0.508	0.36
86_L	288_A	0.508	0.36
187_M	319_G	0.507	0.36
389_M	446_S	0.506	0.36
59_L	355_D	0.506	0.36
458_R	461_P	0.505	0.36
107_A	293_A	0.505	0.36
81_R	248_V	0.505	0.36
72_A	295_L	0.504	0.36
151_W	360_S	0.504	0.36
88_T	224_G	0.503	0.36
417_K	429_G	0.501	0.36
357_S	421_L	0.501	0.36
205_R	226_L	0.501	0.36
346_V	376_Y	0.501	0.36
159_C	307_D	0.501	0.36
22_N	25_E	0.500	0.35
44_G	190_I	0.500	0.35
206_T	239_S	0.500	0.35

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1w5dA	1	0.9308	100	0.257	Contact Map
2ex2A	2	0.956	100	0.267	Contact Map
1w79A	1	0.9455	100	0.272	Contact Map
3a3dA	2	0.9497	100	0.282	Contact Map
3v39A	1	0.7673	100	0.481	Contact Map
4mxgA	1	0.5178	99.9	0.81	Contact Map
3p09A	3	0.5178	99.9	0.812	Contact Map
3dw0A	1	0.5283	99.9	0.818	Contact Map
1bueA	1	0.5178	99.9	0.819	Contact Map
1w7fA	1	0.5115	99.9	0.82	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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