GREMLIN Database
RHSE - Putative protein RhsE
UniProt: P24211 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10010
Length: 682 (549)
Sequences: 195 (138)
Seq/√Len: 5.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
24_D28_R4.7530.98
480_Q492_R4.5510.97
490_Y495_H4.4800.96
230_R259_H4.2840.95
508_P533_L4.0490.94
226_D230_R3.6040.89
480_Q491_N3.5660.88
124_T128_Q3.4240.86
55_N59_L3.1420.80
190_D194_N3.0480.78
215_I218_D2.9620.76
460_G532_G2.9580.76
30_T33_R2.8650.74
289_K485_E2.7890.72
572_D575_V2.5930.66
96_R215_I2.5930.66
256_D495_H2.5180.63
492_R531_M2.4620.61
79_G487_G2.4550.61
281_D286_R2.4130.60
452_W503_Y2.4040.59
555_I558_N2.4040.59
256_D486_S2.3910.59
582_A586_M2.3640.58
174_V458_E2.3540.58
76_Y80_Y2.3350.57
146_N150_D2.2940.56
568_G572_D2.2820.55
579_H583_A2.2520.54
575_V579_H2.2440.54
524_P529_D2.2030.52
209_V215_I2.1600.51
480_Q531_M2.1480.50
76_Y102_E2.1370.50
569_Y574_I2.1130.49
565_Y570_D2.0820.48
569_Y572_D2.0730.48
55_N75_T2.0530.47
261_L286_R2.0530.47
260_R286_R2.0500.47
401_S408_C2.0310.46
567_F585_A2.0300.46
570_D582_A2.0100.46
189_T215_I2.0100.46
166_S523_N1.9980.45
459_W476_R1.9900.45
195_R481_Q1.9880.45
338_S341_P1.9830.45
494_R507_D1.9800.45
575_V586_M1.9770.44
460_G494_R1.9730.44
494_R532_G1.9730.44
566_Q570_D1.9600.44
540_T544_L1.9470.43
487_G496_Y1.9370.43
278_Y289_K1.9330.43
496_Y520_Y1.9210.43
280_Y284_G1.9080.42
96_R189_T1.9010.42
401_S410_L1.8850.41
570_D583_A1.8730.41
523_N530_P1.8720.41
568_G575_V1.8580.40
478_P503_Y1.8270.39
253_Y261_L1.8150.39
194_N213_N1.8110.39
503_Y511_L1.8020.39
256_D490_Y1.7800.38
579_H586_M1.7630.37
569_Y575_V1.7490.37
457_D461_N1.7460.37
261_L490_Y1.7390.36
187_Y195_R1.7380.36
572_D582_A1.7360.36
256_D260_R1.6890.35
79_G508_P1.6850.35
58_G193_G1.6790.34
575_V582_A1.6680.34
497_D530_P1.6540.34
488_L514_G1.6390.33
50_T171_L1.6360.33
460_G507_D1.6350.33
507_D532_G1.6350.33
96_R209_V1.6260.33
568_G582_A1.6240.33
230_R282_P1.6230.33
60_A129_L1.6180.33
226_D286_R1.6010.32
554_L558_N1.5820.31
145_W507_D1.5810.31
100_H105_R1.5770.31
194_N280_Y1.5740.31
494_R529_D1.5700.31
574_I586_M1.5690.31
576_G586_M1.5680.31
170_R485_E1.5350.30
585_A590_Y1.5340.30
566_Q572_D1.5280.30
16_R33_R1.5260.30
583_A590_Y1.5230.30
508_P517_M1.5210.30
203_P210_W1.5210.30
580_N583_A1.5170.30
568_G579_H1.5150.29
255_Y505_T1.5100.29
570_D579_H1.5040.29
517_M531_M1.5020.29
170_R489_Y1.4920.29
278_Y282_P1.4880.29
207_L215_I1.4820.29
580_N585_A1.4780.28
564_A574_I1.4760.28
75_T522_L1.4680.28
578_A588_H1.4640.28
566_Q575_V1.4610.28
166_S458_E1.4480.28
265_T486_S1.4410.27
579_H590_Y1.4320.27
564_A568_G1.4320.27
580_N586_M1.4320.27
14_G17_V1.4310.27
564_A578_A1.4300.27
565_Y579_H1.4240.27
255_Y477_L1.4230.27
554_L557_A1.4200.27
554_L559_S1.4180.27
565_Y572_D1.4160.27
251_H292_W1.4130.27
80_Y100_H1.4040.26
404_W408_C1.4040.26
96_R100_H1.3980.26
406_A409_G1.3870.26
509_I516_N1.3850.26
574_I583_A1.3850.26
476_R503_Y1.3820.26
165_Y171_L1.3800.26
545_I556_A1.3730.26
75_T96_R1.3700.25
452_W476_R1.3690.25
253_Y260_R1.3690.25
579_H588_H1.3590.25
571_M584_D1.3590.25
187_Y503_Y1.3590.25
225_H284_G1.3580.25
121_S169_G1.3560.25
223_Y226_D1.3520.25
259_H503_Y1.3510.25
572_D577_G1.3500.25
400_E404_W1.3500.25
286_R433_H1.3470.25
16_R20_H1.3450.25
189_T209_V1.3420.25
226_D229_G1.3380.25
281_D448_G1.3360.25
97_D191_P1.3350.25
566_Q574_I1.3330.24
75_T145_W1.3310.24
520_Y529_D1.3290.24
569_Y582_A1.3280.24
496_Y529_D1.3260.24
466_E470_H1.3240.24
97_D101_R1.3170.24
545_I553_G1.3170.24
575_V585_A1.3170.24
183_I255_Y1.3140.24
208_T211_P1.3000.24
150_D159_Q1.2990.24
207_L211_P1.2990.24
234_K253_Y1.2940.23
550_G555_I1.2930.23
257_S286_R1.2920.23
553_G558_N1.2890.23
270_G284_G1.2890.23
565_Y569_Y1.2850.23
527_V535_A1.2830.23
503_Y531_M1.2750.23
567_F591_L1.2720.23
564_A586_M1.2640.23
552_P559_S1.2580.23
564_A582_A1.2440.22
213_N223_Y1.2430.22
128_Q474_P1.2400.22
578_A581_G1.2380.22
438_G483_D1.2290.22
335_E344_R1.2250.22
568_G586_M1.2230.22
545_I550_G1.2220.22
507_D529_D1.2160.22
460_G529_D1.2160.22
529_D532_G1.2160.22
542_G547_A1.2160.22
458_E477_L1.2030.21
576_G590_Y1.2030.21
564_A572_D1.2000.21
581_G586_M1.2000.21
562_N575_V1.2000.21
432_Y495_H1.1960.21
566_Q569_Y1.1900.21
547_A553_G1.1870.21
567_F570_D1.1870.21
430_H462_Q1.1800.21
306_R313_Y1.1790.21
480_Q509_I1.1790.21
572_D579_H1.1770.21
568_G574_I1.1770.21
586_M589_C1.1770.21
575_V583_A1.1770.21
232_T550_G1.1760.21
487_G520_Y1.1760.21
525_I552_P1.1740.21
435_D438_G1.1730.21
226_D259_H1.1720.21
164_G317_G1.1720.21
564_A570_D1.1710.20
516_N522_L1.1710.20
223_Y456_Y1.1700.20
568_G580_N1.1700.20
229_G524_P1.1620.20
226_D284_G1.1550.20
375_V389_E1.1540.20
150_D169_G1.1500.20
195_R516_N1.1490.20
329_R337_G1.1480.20
107_F169_G1.1430.20
190_D251_H1.1420.20
79_G154_I1.1380.20
286_R490_Y1.1340.20
578_A589_C1.1330.20
478_P492_R1.1330.20
97_D489_Y1.1300.20
433_H440_P1.1240.19
189_T518_Y1.1220.19
571_M575_V1.1220.19
340_T343_I1.1200.19
57_Q255_Y1.1160.19
567_F579_H1.1130.19
22_G33_R1.1100.19
405_L409_G1.1080.19
553_G556_A1.1070.19
493_H514_G1.1070.19
76_Y96_R1.1060.19
577_G580_N1.1010.19
583_A587_R1.1000.19
280_Y494_R1.0990.19
102_E202_H1.0980.19
164_G291_V1.0960.19
547_A581_G1.0950.19
546_Y549_S1.0940.19
165_Y494_R1.0940.19
226_D281_D1.0930.19
66_D71_V1.0920.19
229_G284_G1.0880.19
208_T497_D1.0830.19
496_Y516_N1.0820.19
586_M591_L1.0810.19
21_Y286_R1.0810.19
313_Y323_V1.0740.18
81_L111_A1.0710.18
66_D495_H1.0700.18
569_Y573_A1.0700.18
567_F573_A1.0640.18
564_A573_A1.0630.18
565_Y574_I1.0620.18
586_M590_Y1.0610.18
56_E457_D1.0610.18
540_T557_A1.0530.18
503_Y516_N1.0520.18
341_P344_R1.0500.18
488_L530_P1.0500.18
124_T130_Q1.0460.18
566_Q573_A1.0460.18
337_G340_T1.0460.18
571_M590_Y1.0450.18
29_L33_R1.0430.18
567_F572_D1.0420.18
555_I561_T1.0410.18
166_S189_T1.0370.18
368_G371_N1.0360.18
331_Q337_G1.0340.18
59_L433_H1.0280.17
450_T453_R1.0280.17
565_Y575_V1.0270.17
307_K311_T1.0250.17
492_R520_Y1.0240.17
516_N520_Y1.0230.17
480_Q528_I1.0220.17
198_D491_N1.0200.17
556_A571_M1.0180.17
259_H316_D1.0150.17
490_Y530_P1.0140.17
55_N433_H1.0120.17
571_M585_A1.0100.17
542_G545_I1.0050.17
256_D261_L1.0020.17
101_R150_D1.0000.17
571_M574_I0.9970.17
209_V230_R0.9970.17
150_D493_H0.9960.17
564_A575_V0.9950.17
564_A580_N0.9950.17
565_Y582_A0.9930.17
127_G149_G0.9930.17
169_G491_N0.9930.17
257_S501_G0.9900.17
226_D448_G0.9900.17
143_Y165_Y0.9900.17
58_G501_G0.9880.17
34_Q58_G0.9880.17
455_E466_E0.9860.17
320_L342_L0.9860.17
166_S494_R0.9790.16
321_T324_Q0.9780.16
260_R490_Y0.9770.16
441_L501_G0.9770.16
582_A589_C0.9770.16
514_G533_L0.9730.16
166_S174_V0.9720.16
582_A590_Y0.9720.16
255_Y258_Q0.9720.16
565_Y585_A0.9680.16
179_P317_G0.9650.16
546_Y559_S0.9650.16
24_D34_Q0.9620.16
575_V580_N0.9610.16
545_I548_V0.9610.16
581_G590_Y0.9580.16
521_P533_L0.9560.16
23_Y150_D0.9550.16
577_G583_A0.9530.16
335_E338_S0.9520.16
566_Q582_A0.9510.16
581_G587_R0.9460.16
570_D575_V0.9430.16
563_S569_Y0.9400.16
129_L477_L0.9380.16
452_W478_P0.9360.16
66_D490_Y0.9360.16
330_I333_V0.9330.16
572_D583_A0.9330.16
585_A588_H0.9320.16
365_Q368_G0.9300.16
478_P491_N0.9290.15
267_I270_G0.9280.15
173_S196_L0.9280.15
573_A582_A0.9220.15
166_S209_V0.9220.15
576_G581_G0.9210.15
108_G488_L0.9210.15
203_P207_L0.9210.15
83_G216_A0.9170.15
193_G496_Y0.9150.15
280_Y456_Y0.9130.15
92_L105_R0.9120.15
146_N152_V0.9100.15
494_R524_P0.9100.15
539_M548_V0.9090.15
523_N526_Q0.9070.15
565_Y586_M0.9070.15
167_A232_T0.9070.15
146_N438_G0.9050.15
491_N531_M0.8970.15
205_S218_D0.8920.15
190_D494_R0.8920.15
493_H533_L0.8910.15
212_D576_G0.8800.15
100_H465_E0.8770.15
281_D529_D0.8750.15
65_P71_V0.8740.15
542_G553_G0.8740.15
109_S444_I0.8680.14
189_T494_R0.8680.14
486_S490_Y0.8680.14
286_R483_D0.8630.14
131_S142_D0.8620.14
555_I575_V0.8610.14
509_I531_M0.8600.14
73_W96_R0.8590.14
303_S306_R0.8580.14
286_R438_G0.8560.14
303_S307_K0.8540.14
572_D580_N0.8530.14
281_D438_G0.8520.14
100_H209_V0.8520.14
457_D478_P0.8510.14
171_L420_E0.8510.14
581_G588_H0.8490.14
541_S546_Y0.8460.14
278_Y284_G0.8460.14
89_T518_Y0.8460.14
122_T130_Q0.8440.14
431_F437_R0.8440.14
551_V556_A0.8440.14
569_Y577_G0.8440.14
334_Y338_S0.8420.14
534_D575_V0.8410.14
260_R466_E0.8390.14
400_E403_A0.8380.14
579_H585_A0.8370.14
368_G372_G0.8370.14
572_D586_M0.8360.14
567_F583_A0.8350.14
553_G578_A0.8350.14
570_D580_N0.8340.14
565_Y568_G0.8310.14
574_I579_H0.8270.14
400_E410_L0.8260.14
194_N501_G0.8240.14
289_K523_N0.8240.14
284_G460_G0.8220.14
284_G532_G0.8220.14
564_A571_M0.8170.14
402_R406_A0.8150.14
229_G494_R0.8150.14
547_A558_N0.8130.13
193_G460_G0.8120.13
193_G532_G0.8120.13
400_E408_C0.8100.13
405_L408_C0.8090.13
486_S495_H0.8090.13
55_N486_S0.8090.13
568_G590_Y0.8080.13
489_Y498_P0.8070.13
481_Q503_Y0.8060.13
387_R396_R0.8050.13
36_V436_H0.8040.13
22_G29_L0.8030.13
145_W438_G0.8030.13
568_G589_C0.8020.13
486_S520_Y0.8020.13
491_N503_Y0.8020.13
487_G495_H0.8000.13
572_D590_Y0.8000.13
229_G448_G0.7970.13
317_G386_D0.7970.13
74_L83_G0.7970.13
113_S171_L0.7960.13
367_E371_N0.7960.13
377_F388_L0.7950.13
568_G583_A0.7930.13
104_V112_G0.7930.13
572_D585_A0.7910.13
403_A410_L0.7910.13
256_D278_Y0.7900.13
145_W494_R0.7900.13
581_G589_C0.7900.13
460_G496_Y0.7890.13
496_Y532_G0.7890.13
491_N511_L0.7870.13
526_Q537_E0.7870.13
506_P510_G0.7870.13
81_L485_E0.7860.13
335_E343_I0.7860.13
228_Y259_H0.7860.13
187_Y501_G0.7860.13
564_A590_Y0.7850.13
433_H444_I0.7850.13
308_P311_T0.7800.13
511_L531_M0.7800.13
570_D574_I0.7780.13
320_L324_Q0.7770.13
31_G501_G0.7740.13
388_L391_E0.7740.13
256_D465_E0.7680.13
496_Y507_D0.7650.13
465_E483_D0.7640.13
355_A358_R0.7630.13
143_Y529_D0.7620.13
335_E345_V0.7620.13
255_Y436_H0.7590.13
127_G193_G0.7580.13
494_R518_Y0.7560.13
147_D326_D0.7540.13
436_H483_D0.7540.13
541_S551_V0.7510.12
572_D587_R0.7500.12
528_I561_T0.7500.12
96_R207_L0.7490.12
563_S568_G0.7450.12
460_G479_G0.7440.12
479_G532_G0.7440.12
573_A590_Y0.7430.12
569_Y587_R0.7420.12
225_H287_M0.7410.12
400_E405_L0.7410.12
305_S309_E0.7400.12
100_H459_W0.7400.12
372_G376_V0.7390.12
28_R128_Q0.7380.12
322_T327_T0.7380.12
564_A587_R0.7340.12
169_G457_D0.7340.12
35_T47_H0.7330.12
573_A586_M0.7330.12
573_A577_G0.7330.12
17_V21_Y0.7310.12
79_G101_R0.7310.12
172_E459_W0.7310.12
427_R435_D0.7310.12
576_G583_A0.7300.12
192_A213_N0.7290.12
483_D516_N0.7270.12
478_P510_G0.7270.12
17_V109_S0.7250.12
403_A409_G0.7240.12
173_S247_D0.7230.12
554_L580_N0.7220.12
539_M563_S0.7220.12
314_G317_G0.7200.12
537_E552_P0.7200.12
579_H587_R0.7200.12
198_D490_Y0.7180.12
401_S404_W0.7170.12
282_P289_K0.7150.12
280_Y460_G0.7140.12
280_Y532_G0.7140.12
313_Y320_L0.7130.12
280_Y507_D0.7130.12
276_S286_R0.7110.12
565_Y581_G0.7100.12
571_M581_G0.7090.12
255_Y501_G0.7070.12
20_H29_L0.7030.12
229_G529_D0.7030.12
334_Y344_R0.7010.12
78_S102_E0.7010.12
234_K264_Y0.7000.12
97_D460_G0.6980.12
97_D532_G0.6980.12
555_I559_S0.6970.12
105_R473_Q0.6970.12
190_D456_Y0.6970.12
257_S260_R0.6970.12
73_W94_F0.6960.12
574_I577_G0.6960.12
331_Q334_Y0.6920.12
566_Q586_M0.6910.12
440_P503_Y0.6890.12
88_G178_A0.6880.12
186_P203_P0.6880.12
540_T543_G0.6870.12
189_T522_L0.6860.12
539_M544_L0.6860.12
563_S566_Q0.6830.11
575_V590_Y0.6830.11
236_D247_D0.6800.11
265_T380_E0.6800.11
15_H18_S0.6800.11
86_L96_R0.6790.11
141_R169_G0.6790.11
165_Y460_G0.6770.11
165_Y532_G0.6770.11
553_G557_A0.6770.11
383_R391_E0.6770.11
53_A62_R0.6770.11
165_Y507_D0.6760.11
230_R261_L0.6760.11
565_Y590_Y0.6740.11
226_D261_L0.6740.11
164_G451_A0.6740.11
480_Q503_Y0.6740.11
545_I571_M0.6720.11
534_D537_E0.6710.11
548_V559_S0.6710.11
193_G497_D0.6700.11
262_V482_H0.6700.11
58_G149_G0.6680.11
24_D255_Y0.6680.11
59_L110_M0.6670.11
561_T567_F0.6670.11
348_E497_D0.6660.11
32_E35_T0.6650.11
110_M520_Y0.6650.11
44_L64_T0.6650.11
520_Y530_P0.6650.11
302_M306_R0.6650.11
495_H520_Y0.6650.11
218_D500_Q0.6640.11
30_T293_R0.6640.11
256_D487_G0.6630.11
130_Q140_D0.6620.11
477_L499_L0.6620.11
123_Y129_L0.6600.11
96_R315_W0.6590.11
540_T550_G0.6580.11
154_I436_H0.6550.11
409_G413_E0.6540.11
519_Q522_L0.6530.11
563_S570_D0.6530.11
426_A449_N0.6500.11
165_Y194_N0.6500.11
478_P481_Q0.6490.11
436_H477_L0.6490.11
229_G286_R0.6490.11
435_D451_A0.6480.11
236_D282_P0.6480.11
97_D133_H0.6470.11
225_H280_Y0.6470.11
560_I581_G0.6470.11
334_Y523_N0.6460.11
310_V359_S0.6460.11
565_Y589_C0.6450.11
577_G584_D0.6440.11
584_D589_C0.6430.11
179_P549_S0.6410.11
257_S278_Y0.6410.11
189_T280_Y0.6400.11
286_R289_K0.6380.11
570_D573_A0.6380.11
337_G341_P0.6370.11
121_S150_D0.6360.11
23_Y207_L0.6350.11
575_V589_C0.6340.11
159_Q492_R0.6330.11
169_G426_A0.6310.11
566_Q590_Y0.6300.11
544_L550_G0.6290.11
282_P480_Q0.6280.11
187_Y200_E0.6280.11
580_N587_R0.6280.11
76_Y214_R0.6260.11
165_Y190_D0.6260.11
541_S554_L0.6250.11
548_V555_I0.6250.11
403_A407_Q0.6240.11
157_P411_T0.6230.11
549_S552_P0.6230.11
552_P558_N0.6230.11
73_W431_F0.6230.11
550_G557_A0.6220.11
392_I396_R0.6220.11
278_Y486_S0.6210.11
402_R411_T0.6210.11
503_Y509_I0.6210.11
102_E105_R0.6190.11
476_R492_R0.6190.11
260_R438_G0.6190.11
192_A196_L0.6190.11
429_V486_S0.6190.11
26_K36_V0.6180.11
261_L431_F0.6170.11
101_R151_L0.6170.11
79_G141_R0.6160.11
565_Y584_D0.6150.11
223_Y280_Y0.6120.11
496_Y533_L0.6120.11
166_S493_H0.6110.10
583_A586_M0.6110.10
62_R72_E0.6100.10
102_E149_G0.6090.10
476_R491_N0.6070.10
551_V558_N0.6060.10
96_R494_R0.6050.10
230_R286_R0.6050.10
230_R284_G0.6050.10
531_M557_A0.6030.10
79_G524_P0.6030.10
389_E397_V0.6030.10
52_H440_P0.6020.10
84_M335_E0.6020.10
255_Y467_N0.6000.10
377_F382_V0.5990.10
104_V149_G0.5990.10
536_I581_G0.5990.10
487_G530_P0.5990.10
386_D396_R0.5980.10
557_A582_A0.5980.10
129_L132_Q0.5970.10
258_Q286_R0.5970.10
275_E289_K0.5960.10
572_D589_C0.5940.10
487_G529_D0.5920.10
60_A76_Y0.5900.10
24_D99_L0.5900.10
102_E502_R0.5900.10
204_D374_G0.5890.10
577_G582_A0.5870.10
289_K481_Q0.5870.10
146_N490_Y0.5860.10
402_R405_L0.5860.10
87_G500_Q0.5850.10
582_A585_A0.5840.10
339_F342_L0.5840.10
260_R474_P0.5810.10
311_T317_G0.5790.10
568_G585_A0.5790.10
140_D144_G0.5790.10
382_V385_L0.5790.10
289_K480_Q0.5780.10
54_Y84_M0.5780.10
127_G176_T0.5770.10
171_L508_P0.5770.10
574_I582_A0.5760.10
77_G100_H0.5750.10
377_F383_R0.5750.10
60_A479_G0.5740.10
525_I569_Y0.5740.10
80_Y97_D0.5740.10
569_Y578_A0.5740.10
578_A584_D0.5740.10
141_R501_G0.5730.10
572_D591_L0.5730.10
493_H520_Y0.5730.10
125_P128_Q0.5720.10
310_V316_D0.5720.10
255_Y513_G0.5710.10
400_E409_G0.5700.10
435_D461_N0.5700.10
307_K327_T0.5690.10
206_T323_V0.5680.10
564_A589_C0.5680.10
223_Y311_T0.5670.10
426_A455_E0.5660.10
493_H523_N0.5660.10
438_G495_H0.5650.10
251_H290_R0.5650.10
201_L486_S0.5650.10
129_L176_T0.5640.10
335_E348_E0.5630.10
100_H152_V0.5620.10
359_S448_G0.5610.10
281_D474_P0.5610.10
576_G579_H0.5610.10
75_T225_H0.5600.10
121_S207_L0.5590.10
27_G261_L0.5590.10
437_R483_D0.5590.10
229_G497_D0.5570.10
316_D323_V0.5570.10
551_V571_M0.5550.10
539_M547_A0.5550.10
539_M542_G0.5540.10
551_V554_L0.5540.10
546_Y554_L0.5530.10
478_P509_I0.5520.10
527_V533_L0.5510.10
141_R156_G0.5480.10
192_A490_Y0.5480.10
63_V390_E0.5460.10
94_F105_R0.5460.10
169_G461_N0.5460.10
487_G524_P0.5450.10
494_R501_G0.5450.10
105_R259_H0.5450.10
446_E449_N0.5450.10
490_Y515_W0.5440.10
166_S183_I0.5430.10
190_D516_N0.5420.10
579_H582_A0.5410.10
502_R505_T0.5410.10
406_A410_L0.5390.10
491_N509_I0.5390.10
367_E393_R0.5390.10
439_L456_Y0.5380.10
96_R121_S0.5370.10
539_M551_V0.5370.10
187_Y452_W0.5360.10
290_R421_P0.5350.10
556_A578_A0.5340.10
492_R511_L0.5340.10
52_H189_T0.5340.10
568_G576_G0.5340.10
432_Y490_Y0.5340.10
196_L445_S0.5330.10
458_E481_Q0.5330.10
128_Q132_Q0.5320.09
199_P214_R0.5320.09
86_L100_H0.5310.09
401_S413_E0.5310.09
577_G591_L0.5300.09
199_P342_L0.5300.09
100_H124_T0.5290.09
318_D321_T0.5280.09
24_D58_G0.5270.09
54_Y71_V0.5270.09
287_M470_H0.5270.09
27_G514_G0.5270.09
577_G589_C0.5260.09
166_S507_D0.5260.09
491_N501_G0.5260.09
176_T486_S0.5250.09
477_L489_Y0.5240.09
170_R289_K0.5230.09
564_A569_Y0.5230.09
553_G559_S0.5230.09
563_S572_D0.5230.09
62_R168_T0.5220.09
460_G524_P0.5220.09
524_P532_G0.5220.09
566_Q583_A0.5210.09
568_G573_A0.5200.09
584_D587_R0.5200.09
56_E258_Q0.5200.09
528_I552_P0.5190.09
507_D524_P0.5180.09
54_Y73_W0.5180.09
174_V433_H0.5170.09
219_A235_T0.5170.09
568_G577_G0.5160.09
481_Q491_N0.5130.09
73_W437_R0.5120.09
143_Y496_Y0.5110.09
370_E378_P0.5110.09
128_Q495_H0.5100.09
574_I585_A0.5090.09
483_D486_S0.5080.09
548_V554_L0.5080.09
576_G591_L0.5080.09
24_D498_P0.5080.09
565_Y583_A0.5080.09
21_Y32_E0.5070.09
275_E290_R0.5070.09
124_T213_N0.5070.09
146_N495_H0.5060.09
55_N97_D0.5050.09
338_S344_R0.5050.09
392_I395_D0.5040.09
200_E503_Y0.5030.09
565_Y577_G0.5030.09
400_E406_A0.5030.09
454_G473_Q0.5020.09
207_L481_Q0.5010.09
566_Q591_L0.5010.09
208_T287_M0.5010.09
309_E313_Y0.5000.09
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4o9xA 1 0.6408 100 0.546 Contact Map
4iglB 1 0.6261 100 0.548 Contact Map
4iglA 1 0.3886 99.7 0.885 Contact Map
4ghbA 5 0.3416 97.2 0.952 Contact Map
1q7fA 1 0.3607 88.4 0.968 Contact Map
4ld1A 1 0.2258 81.1 0.971 Contact Map
4r8oA 2 0.1378 76.4 0.973 Contact Map
3e5zA 1 0.349 76.2 0.973 Contact Map
4r03A 1 0.151 74.8 0.973 Contact Map
3no2A 1 0.3768 71.6 0.973 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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