PHEP - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

PHEP - Phenylalanine-specific permease

UniProt:	P24207	Sequences: MKNASTVSEDTASNQEPTLHRGLHNRHIQLIALGGAIGTGLFLGIGPAIQMAGPAVLLGYGVAGIIAFLIMRQLGEMVVEEPVSGSFAHFAYKYWGPFAGFLSGWNYWVMFVLVGMAELTAAGIYMQYWFPDVPTWIWAAAFFIIINAVNLVNVRLYGETEFWFALIKVLAIIGMIGFGLWLLFSGHGGEKASIDNLWRYGGFFATGWNGLILSLAVIMFSFGGLELIGITAAEARDPEKSIPKAVNQVVYRILLFYIGSLVVLLALYPWVEVKSNSSPFVMIFHNLDSNVVASALNFVILVASLSVYNSGVYSNSRMLFGLSVQGNAPKFLTRVSRRGVPINSLMLSGAITSLVVLINYLLPQKAFGLLMALVVATLLLNWIMICLAHLRFRAAMRRQGRETQFKALLYPFGNYLCIAFLGMILLLMCTMDDMRLSAILLPVWIVFLFMAFKTLRRK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10708
Length:	458 (422)
Sequences:	24768 (15913)
Seq/√Len:	774.6

ECOLI - PHEP AROP CYCA GABP YIFK ANSP LYSP PROY MMUP PUUP PLAP POTE FRLA GADC YCAM YGJI ADIC YJEM YBAT CADB ARCD YJEH TNAB MTR TYRP
BACSU - AAPA YDGF YBGF ROCC HUTM YTNA YVBW YBXG YHDG GABP ROCE YFNA YCGH ASPP YBEC STET ARCD YECA YDAO GERBB YNDE GERAB GERKB YFKT
HALSA - Q9HHU7 Q9HQB3 Q9HSL5
SULSO - Q97XM0 Q97Z63 Q97U05 Q97X49 Q97WS3 Q97ZB5 Q97VA6 Q97U33 Q7LXI7 Q97VA8 Q97WD4 Q97VR4 Q97Y76 Q97YN3 Q97YX9 Q97U39

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
147_N	349_G	4.479	1.00
331_F	343_N	4.370	1.00
391_R	395_A	3.522	1.00
383_I	418_I	3.281	1.00
64_G	254_L	3.270	1.00
334_R	343_N	3.156	1.00
240_K	244_K	3.040	1.00
88_A	325_Q	2.826	1.00
24_H	236_R	2.825	1.00
235_A	241_S	2.763	1.00
104_G	322_L	2.729	1.00
237_D	240_K	2.680	1.00
29_Q	248_Q	2.629	1.00
323_S	333_T	2.588	1.00
336_S	342_I	2.557	1.00
140_A	353_S	2.543	1.00
179_G	263_V	2.493	1.00
331_F	334_R	2.468	1.00
233_A	324_V	2.455	1.00
25_N	248_Q	2.375	1.00
439_I	443_V	2.357	1.00
76_E	393_R	2.305	1.00
92_Y	100_G	2.293	1.00
386_C	417_C	2.280	1.00
177_G	181_W	2.255	1.00
234_E	317_R	2.253	1.00
148_A	152_V	2.199	1.00
282_M	285_H	2.191	1.00
320_F	324_V	2.179	1.00
443_V	446_V	2.175	1.00
346_M	350_A	2.168	1.00
25_N	241_S	2.110	1.00
95_W	391_R	2.091	1.00
144_I	353_S	2.088	1.00
155_R	159_E	2.084	1.00
25_N	29_Q	2.084	1.00
147_N	345_L	2.081	1.00
28_I	235_A	2.079	1.00
291_V	295_A	2.072	1.00
415_Y	419_A	2.041	1.00
244_K	248_Q	2.021	1.00
166_L	170_L	2.003	1.00
151_L	342_I	2.001	1.00
29_Q	252_R	1.980	1.00
139_A	356_V	1.951	1.00
326_G	330_K	1.931	1.00
140_A	356_V	1.931	1.00
73_Q	386_C	1.929	1.00
108_W	348_S	1.922	1.00
24_H	27_H	1.910	1.00
92_Y	97_P	1.909	1.00
19_L	335_V	1.907	1.00
336_S	340_V	1.881	1.00
48_A	56_V	1.879	1.00
332_L	347_L	1.866	1.00
65_I	69_L	1.854	1.00
95_W	387_L	1.841	1.00
269_P	272_E	1.808	1.00
272_E	286_N	1.806	1.00
282_M	286_N	1.782	1.00
247_N	251_Y	1.781	1.00
446_V	450_M	1.776	1.00
419_A	423_M	1.766	1.00
237_D	241_S	1.754	1.00
387_L	418_I	1.742	1.00
412_F	416_L	1.737	1.00
150_N	309_N	1.732	1.00
27_H	162_F	1.709	1.00
91_A	103_S	1.708	1.00
23_L	27_H	1.678	1.00
59_G	214_S	1.670	1.00
32_A	249_V	1.661	1.00
103_S	384_M	1.657	1.00
151_L	346_M	1.652	1.00
144_I	349_G	1.649	1.00
66_I	420_F	1.645	1.00
391_R	394_A	1.643	1.00
338_R	342_I	1.641	1.00
251_Y	255_L	1.615	1.00
119_L	308_Y	1.613	1.00
96_G	99_A	1.598	1.00
143_F	352_T	1.598	1.00
170_L	174_G	1.583	1.00
126_M	138_W	1.565	1.00
276_N	282_M	1.554	1.00
63_A	218_I	1.539	1.00
134_P	137_I	1.538	1.00
115_G	352_T	1.516	1.00
193_S	196_N	1.498	1.00
171_A	299_V	1.496	1.00
237_D	244_K	1.495	1.00
319_L	344_S	1.494	1.00
231_T	313_Y	1.482	1.00
119_L	143_F	1.476	1.00
448_L	451_A	1.462	1.00
343_N	347_L	1.459	1.00
315_N	348_S	1.458	1.00
276_N	279_P	1.458	1.00
84_S	233_A	1.449	1.00
443_V	447_F	1.449	1.00
122_A	301_L	1.445	1.00
169_V	173_I	1.444	1.00
436_L	439_I	1.444	1.00
193_S	197_L	1.443	1.00
320_F	335_V	1.441	1.00
387_L	391_R	1.441	1.00
143_F	349_G	1.436	1.00
152_V	338_R	1.435	1.00
447_F	451_A	1.430	1.00
65_I	416_L	1.426	1.00
140_A	144_I	1.422	1.00
180_L	263_V	1.412	1.00
445_I	449_F	1.408	1.00
69_L	416_L	1.401	1.00
147_N	346_M	1.396	1.00
330_K	333_T	1.395	1.00
433_D	447_F	1.393	1.00
330_K	334_R	1.392	1.00
316_S	345_L	1.387	1.00
91_A	384_M	1.375	1.00
19_L	320_F	1.372	1.00
285_H	293_A	1.369	1.00
285_H	290_N	1.365	1.00
71_M	250_V	1.357	1.00
20_H	339_G	1.355	1.00
133_V	137_I	1.342	1.00
442_P	446_V	1.335	1.00
27_H	158_G	1.334	1.00
436_L	443_V	1.333	1.00
238_P	243_P	1.325	1.00
23_L	28_I	1.320	1.00
334_R	342_I	1.319	1.00
294_S	298_F	1.312	1.00
55_A	204_F	1.308	1.00
71_M	246_V	1.298	1.00
81_E	93_K	1.291	1.00
70_I	386_C	1.291	1.00
95_W	99_A	1.287	1.00
43_L	121_A	1.281	1.00
122_A	142_F	1.278	1.00
25_N	244_K	1.276	1.00
23_L	158_G	1.273	1.00
183_L	266_A	1.267	1.00
441_L	445_I	1.266	1.00
435_R	438_A	1.265	1.00
319_L	328_A	1.259	1.00
83_V	89_H	1.259	1.00
72_R	247_N	1.259	1.00
36_A	253_I	1.257	1.00
255_L	259_G	1.256	1.00
94_Y	388_A	1.253	1.00
241_S	244_K	1.252	1.00
176_I	259_G	1.237	1.00
390_L	415_Y	1.236	1.00
432_D	435_R	1.226	1.00
26_R	30_L	1.224	1.00
437_S	441_L	1.217	1.00
409_L	413_G	1.216	1.00
149_V	160_T	1.211	1.00
444_W	448_L	1.208	1.00
89_H	93_K	1.206	1.00
31_I	231_T	1.199	1.00
433_D	436_L	1.195	1.00
83_V	93_K	1.191	1.00
57_L	262_V	1.189	1.00
73_Q	414_N	1.187	1.00
118_E	307_V	1.185	1.00
108_W	319_L	1.183	1.00
423_M	427_L	1.182	1.00
136_W	140_A	1.176	1.00
146_I	308_Y	1.168	1.00
175_M	179_G	1.155	1.00
32_A	228_I	1.152	1.00
422_G	426_L	1.149	1.00
28_I	245_A	1.147	1.00
49_I	56_V	1.138	1.00
434_M	438_A	1.132	1.00
74_L	87_F	1.131	1.00
181_W	186_G	1.118	1.00
400_G	403_T	1.112	1.00
394_A	411_P	1.110	1.00
101_F	105_W	1.110	1.00
193_S	198_W	1.109	1.00
236_R	241_S	1.109	1.00
412_F	415_Y	1.105	1.00
383_I	422_G	1.104	1.00
33_L	252_R	1.103	1.00
439_I	446_V	1.101	1.00
335_V	339_G	1.099	1.00
161_E	309_N	1.097	1.00
55_A	211_L	1.097	1.00
278_S	282_M	1.095	1.00
174_G	178_F	1.091	1.00
350_A	354_L	1.089	1.00
410_Y	414_N	1.089	1.00
324_V	333_T	1.084	1.00
173_I	177_G	1.083	1.00
434_M	437_S	1.082	1.00
78_V	90_F	1.080	1.00
270_W	273_V	1.077	1.00
192_A	195_D	1.075	1.00
180_L	184_F	1.073	1.00
179_G	267_L	1.070	1.00
160_T	164_F	1.069	1.00
389_H	414_N	1.068	1.00
141_A	145_I	1.066	1.00
137_I	141_A	1.065	1.00
88_A	321_G	1.065	1.00
411_P	415_Y	1.064	1.00
61_G	258_I	1.059	1.00
22_G	236_R	1.051	1.00
343_N	346_M	1.049	1.00
159_E	163_W	1.045	1.00
76_E	79_V	1.043	1.00
91_A	99_A	1.032	1.00
79_V	404_Q	1.028	1.00
154_V	313_Y	1.027	1.00
409_L	412_F	1.027	1.00
144_I	148_A	1.013	1.00
123_G	138_W	1.009	1.00
212_I	423_M	1.007	1.00
33_L	253_I	1.006	1.00
147_N	151_L	1.004	1.00
151_L	340_V	1.004	1.00
126_M	130_F	1.003	1.00
232_A	242_I	0.998	1.00
80_E	403_T	0.992	1.00
417_C	421_L	0.989	1.00
439_I	450_M	0.984	1.00
223_G	378_L	0.983	1.00
383_I	421_L	0.982	1.00
418_I	422_G	0.973	1.00
169_V	256_F	0.973	1.00
269_P	286_N	0.967	1.00
164_F	306_S	0.963	1.00
433_D	437_S	0.963	1.00
126_M	301_L	0.959	1.00
196_N	199_R	0.957	1.00
151_L	336_S	0.955	1.00
194_I	197_L	0.954	1.00
439_I	442_P	0.949	1.00
386_C	418_I	0.947	1.00
30_L	162_F	0.945	1.00
176_I	263_V	0.944	1.00
181_W	184_F	0.940	1.00
226_E	230_I	0.935	1.00
57_L	265_L	0.925	1.00
443_V	448_L	0.925	1.00
107_Y	111_F	0.918	1.00
19_L	317_R	0.917	1.00
288_D	292_V	0.916	1.00
26_R	162_F	0.912	1.00
248_Q	252_R	0.911	1.00
85_G	89_H	0.910	1.00
117_A	371_M	0.910	1.00
176_I	180_L	0.909	1.00
254_L	258_I	0.908	1.00
208_W	211_L	0.907	1.00
168_K	303_A	0.905	1.00
117_A	220_F	0.905	1.00
183_L	186_G	0.905	1.00
80_E	401_R	0.904	1.00
279_P	284_F	0.903	1.00
138_W	141_A	0.897	1.00
433_D	439_I	0.896	1.00
332_L	343_N	0.895	1.00
92_Y	325_Q	0.894	1.00
64_G	222_F	0.890	1.00
289_S	292_V	0.887	1.00
146_I	309_N	0.886	1.00
440_L	443_V	0.885	1.00
437_S	443_V	0.885	1.00
435_R	439_I	0.883	1.00
445_I	448_L	0.883	1.00
423_M	426_L	0.881	1.00
402_E	406_K	0.876	1.00
342_I	346_M	0.876	1.00
22_G	155_R	0.867	1.00
399_Q	403_T	0.866	1.00
145_I	305_L	0.864	1.00
69_L	413_G	0.864	1.00
436_L	447_F	0.863	1.00
85_G	88_A	0.863	1.00
328_A	332_L	0.859	1.00
426_L	430_T	0.858	1.00
122_A	305_L	0.858	1.00
383_I	387_L	0.855	1.00
175_M	284_F	0.852	1.00
19_L	234_E	0.851	1.00
195_D	198_W	0.848	1.00
336_S	339_G	0.846	1.00
27_H	159_E	0.846	1.00
204_F	207_G	0.843	1.00
61_G	65_I	0.842	1.00
105_W	328_A	0.839	1.00
436_L	449_F	0.839	1.00
312_V	349_G	0.838	1.00
443_V	450_M	0.838	1.00
181_W	185_S	0.832	1.00
133_V	136_W	0.831	1.00
122_A	304_S	0.826	1.00
148_A	151_L	0.825	1.00
37_I	40_G	0.824	1.00
201_G	205_A	0.823	1.00
262_V	266_A	0.819	1.00
434_M	447_F	0.817	1.00
70_I	421_L	0.814	1.00
204_F	211_L	0.813	1.00
68_F	247_N	0.810	1.00
68_F	72_R	0.810	1.00
127_Q	131_P	0.810	1.00
136_W	356_V	0.808	1.00
58_L	211_L	0.806	1.00
279_P	283_I	0.804	1.00
267_L	283_I	0.803	1.00
446_V	449_F	0.801	1.00
91_A	388_A	0.798	1.00
203_F	206_T	0.795	1.00
120_T	370_L	0.793	1.00
223_G	382_W	0.789	1.00
98_F	102_L	0.789	1.00
69_L	73_Q	0.789	1.00
438_A	442_P	0.788	1.00
55_A	203_F	0.785	1.00
438_A	441_L	0.783	1.00
143_F	356_V	0.780	1.00
213_L	217_V	0.776	1.00
349_G	353_S	0.776	1.00
401_R	404_Q	0.773	1.00
51_M	54_P	0.772	1.00
373_L	377_T	0.772	1.00
433_D	446_V	0.770	1.00
421_L	424_I	0.766	1.00
290_N	294_S	0.766	1.00
159_E	162_F	0.765	1.00
37_I	168_K	0.764	1.00
99_A	384_M	0.764	1.00
80_E	404_Q	0.764	1.00
275_S	279_P	0.762	1.00
207_G	210_G	0.760	1.00
22_G	154_V	0.760	1.00
77_M	389_H	0.755	1.00
243_P	246_V	0.754	1.00
227_L	314_S	0.753	1.00
414_N	418_I	0.746	1.00
123_G	126_M	0.744	1.00
390_L	394_A	0.743	1.00
433_D	443_V	0.742	1.00
341_P	344_S	0.740	1.00
25_N	245_A	0.740	1.00
146_I	312_V	0.736	1.00
439_I	444_W	0.736	1.00
151_L	338_R	0.733	1.00
434_M	439_I	0.732	1.00
152_V	156_L	0.727	1.00
390_L	414_N	0.721	1.00
197_L	201_G	0.718	1.00
127_Q	135_T	0.717	1.00
180_L	259_G	0.716	1.00
194_I	198_W	0.715	1.00
202_G	205_A	0.713	1.00
112_V	351_I	0.712	1.00
36_A	249_V	0.711	1.00
332_L	344_S	0.709	1.00
105_W	443_V	0.708	1.00
279_P	287_L	0.707	1.00
447_F	450_M	0.707	1.00
77_M	90_F	0.706	1.00
58_L	62_V	0.704	1.00
37_I	256_F	0.704	1.00
237_D	243_P	0.703	1.00
331_F	347_L	0.703	1.00
41_L	260_S	0.703	1.00
444_W	447_F	0.702	1.00
425_L	428_M	0.701	1.00
123_G	139_A	0.701	1.00
197_L	200_Y	0.698	1.00
405_F	408_L	0.697	1.00
390_L	411_P	0.696	1.00
19_L	22_G	0.696	1.00
440_L	444_W	0.696	1.00
88_A	92_Y	0.694	1.00
389_H	393_R	0.692	1.00
29_Q	245_A	0.692	1.00
67_A	225_L	0.691	1.00
239_E	404_Q	0.689	1.00
26_R	159_E	0.688	1.00
439_I	449_F	0.687	1.00
337_R	342_I	0.687	1.00
396_M	399_Q	0.685	1.00
123_G	135_T	0.683	1.00
439_I	447_F	0.680	1.00
439_I	448_L	0.679	1.00
284_F	287_L	0.678	1.00
436_L	445_I	0.677	1.00
278_S	281_V	0.677	1.00
158_G	162_F	0.676	1.00
432_D	436_L	0.676	1.00
317_R	320_F	0.675	1.00
393_R	410_Y	0.675	1.00
74_L	385_I	0.674	1.00
350_A	353_S	0.674	1.00
114_V	374_V	0.674	1.00
288_D	291_V	0.672	1.00
116_M	370_L	0.672	1.00
150_N	345_L	0.671	1.00
233_A	320_F	0.671	1.00
113_L	373_L	0.669	1.00
388_A	392_F	0.669	1.00
195_D	199_R	0.668	1.00
410_Y	413_G	0.666	1.00
176_I	260_S	0.666	1.00
438_A	443_V	0.665	1.00
441_L	444_W	0.665	1.00
319_L	347_L	0.665	1.00
150_N	313_Y	0.664	1.00
22_G	26_R	0.663	1.00
57_L	61_G	0.661	1.00
419_A	422_G	0.658	1.00
140_A	357_L	0.657	1.00
114_V	118_E	0.657	1.00
192_A	196_N	0.653	1.00
208_W	212_I	0.653	1.00
58_L	61_G	0.653	1.00
84_S	320_F	0.653	1.00
129_W	297_N	0.653	1.00
179_G	183_L	0.652	1.00
248_Q	251_Y	0.652	1.00
196_N	200_Y	0.651	1.00
376_A	425_L	0.648	1.00
94_Y	391_R	0.647	1.00
29_Q	32_A	0.647	1.00
56_V	261_L	0.646	1.00
69_L	417_C	0.645	1.00
110_M	378_L	0.645	1.00
75_G	79_V	0.643	1.00
38_G	257_Y	0.643	1.00
34_G	165_A	0.642	1.00
192_A	198_W	0.641	1.00
316_S	344_S	0.641	1.00
88_A	104_G	0.641	1.00
156_L	159_E	0.640	1.00
144_I	147_N	0.638	1.00
128_Y	131_P	0.638	1.00
35_G	311_G	0.637	1.00
303_A	306_S	0.633	1.00
183_L	263_V	0.632	1.00
312_V	316_S	0.631	1.00
136_W	139_A	0.627	1.00
35_G	310_S	0.627	1.00
279_P	282_M	0.627	1.00
60_Y	221_S	0.627	1.00
229_G	246_V	0.627	1.00
146_I	305_L	0.626	1.00
199_R	202_G	0.625	1.00
72_R	413_G	0.624	1.00
158_G	309_N	0.624	1.00
167_I	299_V	0.624	1.00
409_L	414_N	0.623	1.00
252_R	256_F	0.622	1.00
26_R	29_Q	0.622	1.00
122_A	126_M	0.621	1.00
116_M	119_L	0.620	1.00
259_G	263_V	0.620	1.00
94_Y	392_F	0.619	1.00
377_T	381_N	0.618	1.00
424_I	428_M	0.618	1.00
87_F	226_E	0.615	1.00
212_I	427_L	0.615	1.00
407_A	410_Y	0.614	1.00
54_P	265_L	0.614	1.00
153_N	156_L	0.612	1.00
129_W	298_F	0.611	1.00
434_M	441_L	0.610	1.00
235_A	242_I	0.609	1.00
45_I	261_L	0.609	1.00
435_R	443_V	0.607	1.00
432_D	439_I	0.606	1.00
128_Y	297_N	0.606	1.00
47_P	368_G	0.605	1.00
78_V	242_I	0.605	1.00
439_I	451_A	0.605	1.00
44_G	371_M	0.602	1.00
242_I	246_V	0.602	1.00
18_T	21_R	0.601	1.00
167_I	171_A	0.600	1.00
95_W	388_A	0.600	1.00
407_A	414_N	0.600	1.00
62_V	215_L	0.600	1.00
223_G	226_E	0.598	1.00
291_V	294_S	0.597	1.00
154_V	231_T	0.596	1.00
234_E	341_P	0.596	1.00
71_M	225_L	0.594	1.00
238_P	241_S	0.594	1.00
260_S	280_F	0.594	1.00
441_L	448_L	0.593	1.00
433_D	438_A	0.591	1.00
252_R	255_L	0.590	1.00
323_S	332_L	0.589	1.00
442_P	445_I	0.589	1.00
111_F	311_G	0.589	1.00
383_I	425_L	0.588	1.00
57_L	258_I	0.588	1.00
210_G	213_L	0.587	1.00
435_R	447_F	0.587	1.00
411_P	414_N	0.587	1.00
106_N	381_N	0.586	1.00
437_S	442_P	0.586	1.00
438_A	448_L	0.584	1.00
48_A	218_I	0.584	1.00
192_A	197_L	0.584	1.00
143_F	353_S	0.582	1.00
126_M	142_F	0.582	1.00
437_S	446_V	0.582	1.00
284_F	289_S	0.580	1.00
418_I	421_L	0.580	1.00
151_L	345_L	0.578	1.00
78_V	229_G	0.578	1.00
379_L	421_L	0.578	1.00
433_D	450_M	0.577	1.00
73_Q	417_C	0.576	1.00
315_N	319_L	0.576	1.00
178_F	182_L	0.575	1.00
230_I	314_S	0.575	1.00
33_L	165_A	0.575	1.00
63_A	219_M	0.574	1.00
335_V	338_R	0.574	1.00
436_L	446_V	0.574	1.00
165_A	168_K	0.574	1.00
77_M	94_Y	0.571	1.00
194_I	266_A	0.571	1.00
260_S	264_L	0.571	1.00
48_A	52_A	0.570	1.00
162_F	166_L	0.569	1.00
435_R	446_V	0.566	1.00
87_F	230_I	0.565	1.00
125_Y	300_I	0.565	1.00
184_F	266_A	0.565	1.00
142_F	308_Y	0.565	1.00
201_G	204_F	0.563	1.00
342_I	345_L	0.563	1.00
435_R	449_F	0.561	1.00
433_D	448_L	0.560	1.00
118_E	308_Y	0.558	1.00
96_G	100_G	0.556	1.00
60_Y	261_L	0.556	1.00
86_S	229_G	0.555	1.00
415_Y	418_I	0.552	1.00
368_G	371_M	0.551	1.00
63_A	222_F	0.549	1.00
437_S	450_M	0.548	1.00
157_Y	313_Y	0.548	1.00
417_C	420_F	0.548	1.00
298_F	302_V	0.547	1.00
205_A	270_W	0.547	1.00
88_A	100_G	0.547	1.00
91_A	100_G	0.546	1.00
437_S	447_F	0.546	1.00
35_G	227_L	0.546	1.00
184_F	192_A	0.545	1.00
145_I	149_V	0.545	1.00
378_L	381_N	0.545	1.00
51_M	213_L	0.544	1.00
407_A	413_G	0.544	1.00
156_L	160_T	0.544	1.00
114_V	117_A	0.543	1.00
103_S	381_N	0.543	1.00
436_L	450_M	0.543	1.00
112_V	348_S	0.542	1.00
353_S	356_V	0.541	1.00
30_L	165_A	0.540	1.00
441_L	446_V	0.540	1.00
421_L	425_L	0.539	1.00
163_W	166_L	0.539	1.00
223_G	374_V	0.539	1.00
283_I	287_L	0.538	1.00
71_M	75_G	0.537	1.00
38_G	168_K	0.537	1.00
116_M	355_V	0.537	1.00
70_I	226_E	0.535	1.00
433_D	444_W	0.535	1.00
142_F	146_I	0.534	1.00
55_A	58_L	0.533	1.00
435_R	442_P	0.532	1.00
319_L	323_S	0.531	1.00
57_L	60_Y	0.530	1.00
119_L	123_G	0.529	1.00
24_H	155_R	0.528	1.00
228_I	242_I	0.528	1.00
252_R	259_G	0.527	1.00
295_A	299_V	0.527	1.00
331_F	335_V	0.526	1.00
170_L	173_I	0.526	1.00
76_E	408_L	0.526	1.00
263_V	266_A	0.524	1.00
427_L	431_M	0.524	1.00
31_I	34_G	0.524	1.00
438_A	447_F	0.524	1.00
410_Y	415_Y	0.524	1.00
317_R	341_P	0.524	1.00
194_I	199_R	0.523	1.00
73_Q	407_A	0.521	1.00
443_V	449_F	0.521	1.00
403_T	406_K	0.520	1.00
118_E	304_S	0.520	1.00
235_A	245_A	0.519	1.00
41_L	44_G	0.519	1.00
239_E	244_K	0.519	1.00
60_Y	257_Y	0.519	1.00
390_L	418_I	0.518	1.00
163_W	167_I	0.518	1.00
281_V	285_H	0.517	1.00
52_A	55_A	0.516	1.00
110_M	377_T	0.516	1.00
347_L	351_I	0.516	1.00
54_P	270_W	0.515	1.00
100_G	104_G	0.514	1.00
441_L	447_F	0.512	1.00
32_A	36_A	0.512	1.00
142_F	305_L	0.512	1.00
317_R	335_V	0.511	1.00
28_I	228_I	0.511	1.00
112_V	355_V	0.509	1.00
135_T	139_A	0.509	1.00
240_K	243_P	0.509	1.00
437_S	440_L	0.509	1.00
234_E	335_V	0.507	1.00
141_A	144_I	0.507	1.00
147_N	312_V	0.506	1.00
68_F	251_Y	0.503	1.00
167_I	302_V	0.501	1.00
442_P	448_L	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3l1lA	2	0.8886	100	0.284	Contact Map
4djkA	2	0.8952	100	0.341	Contact Map
3giaA	1	0.9039	100	0.35	Contact Map
3dh4A	3	0.9127	99.2	0.834	Contact Map
2xq2A	2	0.9127	99.1	0.84	Contact Map
2jlnA	1	0.8886	98.9	0.851	Contact Map
4wgvA	2	0.8057	97.9	0.89	Contact Map
4us3A	1	0.8537	97.2	0.905	Contact Map
2a65A	2	0.9192	96.8	0.91	Contact Map
4xp4A	1	0.9214	96.7	0.911	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0128 seconds.