GREMLIN Database
YGID - Uncharacterized protein YgiD
UniProt: P24197 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11166
Length: 262 (251)
Sequences: 2075 (1445)
Seq/√Len: 91.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
91_R156_E7.4431.00
73_Q77_D5.6491.00
38_R126_D4.0731.00
40_Q157_G3.3271.00
203_E206_P3.3041.00
187_S215_G3.1771.00
145_E148_R3.0441.00
141_A145_E2.7751.00
226_Y230_L2.6841.00
41_A158_I2.6621.00
58_A105_K2.6511.00
85_S130_V2.6251.00
22_D27_R2.6211.00
209_N212_D2.6121.00
7_P154_R2.5331.00
65_I109_G2.4221.00
211_L217_T2.4091.00
93_V105_K2.3021.00
139_P142_W2.2771.00
43_V132_L2.2051.00
166_V192_V2.1901.00
42_I127_I2.1141.00
160_L235_A2.0061.00
78_T119_I1.9751.00
172_T218_L1.9481.00
118_L129_M1.9451.00
86_P89_A1.9041.00
45_V231_Y1.8651.00
54_T135_D1.8521.00
194_A198_W1.8411.00
135_D143_H1.8361.00
192_V226_Y1.8051.00
95_L152_A1.7621.00
43_V160_L1.7551.00
162_A232_V1.7261.00
11_L161_V1.7211.00
12_G165_N1.6811.00
144_F204_Q1.6741.00
55_G106_E1.6621.00
43_V92_L1.6511.00
50_F224_E1.6511.00
57_T131_Q1.6501.00
189_N257_L1.6431.00
210_Y216_G1.6171.00
47_A224_E1.5941.00
147_G234_G1.5791.00
56_V93_V1.5761.00
66_H79_H1.5761.00
6_M122_Y1.5751.00
50_F222_T1.5401.00
55_G104_D1.5201.00
74_A77_D1.5111.00
44_V114_S1.5021.00
53_G135_D1.4991.00
134_I224_E1.4941.00
56_V92_L1.4911.00
93_V103_L1.4701.00
8_A235_A1.4470.99
147_G235_A1.4450.99
63_P108_W1.4370.99
91_R95_L1.4360.99
195_N206_P1.4310.99
138_K142_W1.4300.99
110_F114_S1.4300.99
92_L130_V1.4230.99
50_F136_S1.4220.99
90_Q94_E1.4050.99
95_L153_L1.3910.99
191_Y195_N1.3900.99
191_Y213_H1.3740.99
8_A232_V1.3720.99
165_N256_M1.3520.99
44_V118_L1.3470.99
23_N26_T1.3440.99
68_F115_W1.3430.99
31_K34_M1.3400.99
183_P187_S1.3200.99
44_V161_V1.2970.99
90_Q105_K1.2890.99
189_N255_S1.2880.99
64_T110_F1.2660.99
25_Y248_G1.2490.98
91_R94_E1.2490.98
6_M159_M1.2480.98
83_P86_P1.2220.98
135_D142_W1.2210.98
11_L29_W1.2110.98
40_Q156_E1.2060.98
134_I227_L1.2040.98
92_L95_L1.1950.98
195_N203_E1.1930.98
54_T146_M1.1890.98
81_P125_A1.1660.98
148_R204_Q1.1630.98
209_N213_H1.1600.97
189_N193_K1.1590.97
186_T190_E1.1420.97
84_G89_A1.1410.97
144_F233_L1.1390.97
99_I149_K1.1380.97
244_I257_L1.1120.97
193_K197_T1.1110.97
114_S131_Q1.0970.96
205_H209_N1.0970.96
43_V130_V1.0960.96
41_A88_L1.0930.96
70_G76_Y1.0730.96
189_N247_E1.0710.96
19_V116_G1.0660.96
143_H231_Y1.0580.96
64_T82_A1.0580.96
190_E194_A1.0480.95
151_A237_D1.0470.95
110_F129_M1.0470.95
6_M37_P1.0390.95
88_L92_L1.0320.95
144_F208_V1.0200.95
224_E227_L1.0120.94
56_V105_K1.0110.94
87_A90_Q1.0110.94
56_V132_L1.0100.94
88_L130_V1.0090.94
85_S88_L1.0080.94
140_A210_Y1.0020.94
144_F148_R1.0010.94
94_E98_P0.9990.94
69_G73_Q0.9980.94
210_Y213_H0.9970.94
49_W131_Q0.9940.94
45_V150_L0.9910.94
122_Y159_M0.9900.94
172_T184_W0.9800.93
17_M75_L0.9790.93
6_M157_G0.9740.93
141_A208_V0.9680.93
181_P186_T0.9660.93
75_L115_W0.9620.93
71_F76_Y0.9610.93
43_V158_I0.9490.92
39_P122_Y0.9460.92
11_L117_V0.9410.92
29_W120_K0.9350.92
148_R151_A0.9330.92
90_Q93_V0.9280.91
38_R127_I0.9260.91
42_I80_Y0.9250.91
45_V132_L0.9090.91
39_P127_I0.8990.90
85_S92_L0.8970.90
27_R30_Q0.8830.89
19_V119_I0.8790.89
72_P76_Y0.8780.89
12_G220_N0.8710.89
122_Y126_D0.8640.88
30_Q34_M0.8610.88
15_S18_N0.8570.88
204_Q208_V0.8420.87
96_L149_K0.8410.87
73_Q76_Y0.8410.87
138_K222_T0.8370.87
46_S114_S0.8350.87
185_A249_I0.8350.87
26_T120_K0.8330.86
42_I159_M0.8300.86
64_T79_H0.8300.86
19_V120_K0.8150.85
93_V97_A0.8110.85
28_S258_S0.8070.85
244_I247_E0.8050.84
43_V157_G0.8030.84
46_S57_T0.8030.84
68_F75_L0.8000.84
8_A154_R0.7940.84
145_E149_K0.7920.84
19_V78_T0.7870.83
243_T260_Q0.7820.83
166_V257_L0.7800.83
51_T55_G0.7800.83
24_L248_G0.7730.82
142_W145_E0.7720.82
54_T132_L0.7710.82
22_D26_T0.7640.81
249_I255_S0.7630.81
184_W218_L0.7630.81
52_R137_S0.7610.81
188_F191_Y0.7600.81
28_S31_K0.7590.81
113_G131_Q0.7580.81
211_L223_P0.7560.81
26_T30_Q0.7550.80
82_A110_F0.7520.80
96_L146_M0.7450.80
116_G119_I0.7360.79
182_Y253_S0.7340.79
13_H16_P0.7310.78
152_A155_D0.7280.78
245_P248_G0.7250.78
96_L101_V0.7190.77
223_P227_L0.7170.77
20_L75_L0.7160.77
255_S258_S0.7150.77
57_T110_F0.7130.77
42_I166_V0.7120.76
69_G76_Y0.7110.76
191_Y214_E0.7100.76
50_F134_I0.7080.76
43_V153_L0.7060.76
33_G122_Y0.7020.75
59_M110_F0.7020.75
21_E74_A0.7010.75
19_V75_L0.6990.75
139_P143_H0.6980.75
135_D138_K0.6970.75
9_L35_T0.6970.75
184_W219_S0.6940.75
62_P110_F0.6930.75
9_L32_L0.6870.74
82_A125_A0.6860.74
167_V220_N0.6830.73
230_L233_L0.6750.73
68_F167_V0.6740.72
210_Y223_P0.6720.72
167_V219_S0.6720.72
192_V229_L0.6720.72
193_K244_I0.6720.72
92_L132_L0.6700.72
244_I259_V0.6680.72
20_L74_A0.6650.71
61_T81_P0.6640.71
183_P186_T0.6610.71
17_M21_E0.6600.71
213_H216_G0.6600.71
35_T260_Q0.6580.71
144_F230_L0.6560.70
9_L121_M0.6520.70
247_E257_L0.6490.70
58_A93_V0.6470.69
47_A50_F0.6460.69
143_H227_L0.6450.69
54_T143_H0.6430.69
249_I257_L0.6420.69
9_L260_Q0.6410.69
237_D240_E0.6400.69
124_D145_E0.6380.68
49_W108_W0.6380.68
18_N116_G0.6370.68
63_P107_A0.6350.68
229_L259_V0.6320.68
40_Q85_S0.6310.67
10_F14_G0.6300.67
47_A163_S0.6300.67
33_G36_L0.6290.67
64_T131_Q0.6280.67
39_P42_I0.6280.67
187_S190_E0.6280.67
131_Q163_S0.6270.67
12_G18_N0.6240.67
90_Q148_R0.6240.67
140_A226_Y0.6230.66
65_I115_W0.6230.66
185_A219_S0.6230.66
206_P209_N0.6200.66
64_T81_P0.6200.66
238_G241_P0.6200.66
36_L121_M0.6170.66
57_T130_V0.6130.65
203_E207_L0.6120.65
50_F223_P0.6100.65
62_P81_P0.6070.64
69_G72_P0.6060.64
67_D71_F0.6050.64
154_R157_G0.6050.64
13_H163_S0.6030.64
66_H115_W0.6000.64
51_T133_S0.6000.64
80_Y123_P0.6000.64
11_L121_M0.5990.63
166_V255_S0.5990.63
151_A238_G0.5990.63
100_P145_E0.5980.63
54_T134_I0.5970.63
17_M72_P0.5970.63
60_E86_P0.5960.63
64_T115_W0.5950.63
31_K35_T0.5950.63
204_Q233_L0.5950.63
140_A223_P0.5930.63
95_L158_I0.5930.63
95_L156_E0.5930.63
18_N165_N0.5930.63
140_A227_L0.5900.62
207_L233_L0.5880.62
193_K257_L0.5860.62
138_K143_H0.5830.61
33_G167_V0.5830.61
62_P84_G0.5810.61
193_K247_E0.5800.61
57_T64_T0.5780.61
141_A205_H0.5760.60
210_Y217_T0.5750.60
24_L28_S0.5740.60
208_V230_L0.5730.60
101_V146_M0.5680.59
30_Q120_K0.5670.59
69_G79_H0.5670.59
243_T259_V0.5630.59
97_A102_T0.5630.59
97_A101_V0.5620.59
226_Y240_E0.5620.59
29_W191_Y0.5620.59
101_V149_K0.5620.59
61_T83_P0.5610.58
167_V170_L0.5610.58
198_W203_E0.5600.58
188_F216_G0.5580.58
185_A253_S0.5570.58
167_V184_W0.5570.58
115_W167_V0.5540.58
16_P71_F0.5530.57
181_P184_W0.5530.57
56_V130_V0.5530.57
49_W134_I0.5530.57
17_M20_L0.5530.57
52_R104_D0.5520.57
196_L259_V0.5520.57
210_Y226_Y0.5510.57
178_D181_P0.5510.57
220_N224_E0.5500.57
194_A197_T0.5490.57
129_M159_M0.5490.57
190_E193_K0.5470.57
166_V196_L0.5470.57
65_I170_L0.5460.56
12_G167_V0.5460.56
195_N198_W0.5460.56
44_V162_A0.5440.56
42_I121_M0.5440.56
169_N172_T0.5420.56
90_Q190_E0.5410.56
29_W189_N0.5410.56
41_A153_L0.5410.56
79_H119_I0.5400.56
98_P149_K0.5370.55
204_Q236_W0.5360.55
165_N245_P0.5360.55
32_L36_L0.5350.55
12_G166_V0.5340.55
62_P143_H0.5340.55
223_P230_L0.5330.55
117_V120_K0.5330.55
59_M131_Q0.5270.54
217_T223_P0.5270.54
8_A157_G0.5260.54
47_A225_H0.5200.53
215_G218_L0.5190.53
68_F184_W0.5180.53
154_R240_E0.5170.52
153_L158_I0.5140.52
194_A206_P0.5140.52
199_Q236_W0.5130.52
82_A123_P0.5130.52
10_F13_H0.5120.52
67_D70_G0.5120.52
27_R31_K0.5080.51
140_A234_G0.5070.51
253_S257_L0.5060.51
214_E249_I0.5060.51
248_G251_M0.5050.51
89_A105_K0.5050.51
37_P157_G0.5050.51
48_H168_H0.5030.51
11_L32_L0.5020.50
83_P89_A0.5010.50
30_Q148_R0.5010.50
149_K152_A0.5010.50
134_I234_G0.5000.50
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2pw6A 2 0.9313 100 0.243 Contact Map
1b4uB 2 0.9198 100 0.541 Contact Map
3wraA 2 0.9084 100 0.546 Contact Map
3vsjA 1 0.958 100 0.564 Contact Map
3vsjB 2 0.9504 100 0.589 Contact Map
3bczA 1 0.8969 100 0.664 Contact Map
3hxkA 3 0.6565 80.4 0.954 Contact Map
4lqcA 2 0.4962 66.4 0.959 Contact Map
3bjrA 2 0.6565 64.9 0.959 Contact Map
1fj2A 2 0.6794 63.1 0.96 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0094 seconds.