LNT - ECOLI - GREMLIN Contacts

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LNT - Apolipoprotein N-acyltransferase

UniProt:	P23930	Sequences: MAFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIISLMGLQALTFNRRPLQSAAIGFCWGFGLFGSGINWVYVSIATFGGMPGPVNIFLVVLLAAYLSLYTGLFAGVLSRLWPKTTWLRVAIAAPALWQVTEFLRGWVLTGFPWLQFGYSQIDGPLKGLAPIMGVEAINFLLMMVSGLLALALVKRNWRPLVVAVVLFALPFPLRYIQWFTPQPEKTIQVSMVQGDIPQSLKWDEGQLLNTLKIYYNATAPLMGKSSLIIWPESAITDLEINQQPFLKALDGELRDKGSSLVTGIVDARLNKQNRYDTYNTIITLGKGAPYSYESADRYNKNHLVPFGEFVPLESILRPLAPFFDLPMSSFSRGPYIQPPLSANGIELTAAICYEIILGEQVRDNFRPDTDYLLTISNDAWFGKSIGPWQHFQMARMRALELARPLLRSTNNGITAVIGPQGEIQAMIPQFTREVLTTNVTPTTGLTPYARTGNWPLWVLTALFGFAAVLMSLRQRRK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10168
Length:	512 (479)
Sequences:	3000 (2346)
Seq/√Len:	107.2

ECOLI - LNT

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
167_M	171_A	7.892	1.00
451_V	472_T	5.561	1.00
453_G	457_E	5.315	1.00
462_I	468_E	5.099	1.00
426_F	450_A	4.486	1.00
436_L	484_A	4.328	1.00
316_I	410_I	4.047	1.00
161_K	434_L	4.036	1.00
253_T	265_W	3.988	1.00
432_R	435_E	3.873	1.00
315_T	334_N	3.428	1.00
229_G	249_Y	3.395	1.00
125_A	129_P	3.381	1.00
411_S	444_T	3.262	1.00
57_A	106_G	3.219	1.00
152_G	169_V	2.902	1.00
20_F	43_G	2.876	1.00
433_A	440_L	2.809	1.00
483_Y	488_N	2.755	1.00
226_M	449_T	2.686	1.00
157_D	430_R	2.609	1.00
348_E	364_S	2.590	1.00
225_S	471_T	2.549	1.00
382_L	406_Y	2.479	1.00
288_L	295_L	2.445	1.00
71_G	149_L	2.430	1.00
225_S	260_S	2.415	1.00
18_L	62_C	2.376	1.00
439_P	454_P	2.352	1.00
482_P	486_T	2.236	1.00
301_D	334_N	2.192	1.00
223_Q	473_N	2.174	1.00
35_P	38_I	2.165	1.00
437_A	481_T	2.156	1.00
247_K	251_N	2.094	1.00
440_L	452_I	2.079	1.00
165_P	437_A	2.064	1.00
248_I	467_R	2.053	1.00
439_P	475_T	2.051	1.00
397_R	487_G	2.039	1.00
407_L	440_L	2.038	1.00
226_M	443_S	1.954	1.00
253_T	263_I	1.950	1.00
164_A	431_M	1.945	1.00
155_Q	176_L	1.944	1.00
133_Q	174_F	1.942	1.00
385_A	396_V	1.939	1.00
25_T	70_S	1.936	1.00
300_V	365_F	1.927	1.00
243_L	247_K	1.924	1.00
376_S	381_E	1.910	1.00
352_R	359_D	1.905	1.00
164_A	172_I	1.900	1.00
224_V	441_L	1.876	1.00
165_P	434_L	1.871	1.00
60_G	64_G	1.862	1.00
209_R	212_Q	1.857	1.00
53_P	110_G	1.857	1.00
110_G	114_R	1.825	1.00
24_G	40_S	1.821	1.00
413_D	425_H	1.802	1.00
38_I	180_S	1.798	1.00
138_L	142_V	1.797	1.00
426_F	458_I	1.797	1.00
406_Y	474_V	1.793	1.00
383_T	404_T	1.766	1.00
390_I	440_L	1.764	1.00
60_G	106_G	1.763	1.00
37_A	155_Q	1.733	1.00
14_L	62_C	1.730	1.00
165_P	208_L	1.728	1.00
423_W	448_I	1.723	1.00
449_T	462_I	1.708	1.00
163_L	175_L	1.702	1.00
78_S	416_F	1.689	1.00
383_T	407_L	1.680	1.00
453_G	459_Q	1.677	1.00
46_A	184_A	1.674	1.00
65_F	102_S	1.671	1.00
205_P	208_L	1.659	1.00
137_F	141_W	1.647	1.00
56_S	109_A	1.643	1.00
315_T	332_R	1.627	1.00
17_A	21_G	1.620	1.00
205_P	209_R	1.615	1.00
226_M	470_L	1.609	1.00
33_V	36_A	1.600	1.00
153_Y	428_M	1.595	1.00
225_S	256_L	1.593	1.00
296_V	318_T	1.586	1.00
27_A	37_A	1.584	1.00
72_I	146_F	1.579	1.00
316_I	384_A	1.575	1.00
68_F	139_R	1.567	1.00
40_S	63_W	1.562	1.00
230_D	467_R	1.559	1.00
226_M	441_L	1.544	1.00
166_I	482_P	1.542	1.00
350_I	354_L	1.509	1.00
43_G	180_S	1.504	1.00
318_T	375_L	1.499	1.00
208_L	212_Q	1.496	1.00
189_K	193_R	1.491	1.00
38_I	155_Q	1.481	1.00
390_I	409_T	1.479	1.00
153_Y	431_M	1.477	1.00
61_F	99_A	1.475	1.00
252_A	255_P	1.465	1.00
381_E	405_D	1.459	1.00
209_R	213_W	1.437	1.00
426_F	452_I	1.436	1.00
65_F	69_G	1.419	1.00
112_L	128_A	1.413	1.00
496_A	500_F	1.408	1.00
26_L	31_Y	1.407	1.00
429_A	440_L	1.400	1.00
37_A	154_S	1.398	1.00
337_H	395_Q	1.394	1.00
48_T	109_A	1.392	1.00
93_L	97_L	1.391	1.00
136_E	173_N	1.383	1.00
42_M	180_S	1.380	1.00
460_A	470_L	1.379	1.00
184_A	188_V	1.371	1.00
221_T	473_N	1.367	1.00
225_S	469_V	1.363	1.00
62_C	66_G	1.354	1.00
133_Q	173_N	1.354	1.00
44_L	109_A	1.353	1.00
52_R	55_Q	1.351	1.00
249_Y	269_A	1.348	1.00
413_D	442_R	1.338	0.99
405_D	476_P	1.329	0.99
422_P	464_Q	1.324	0.99
97_L	101_L	1.324	0.99
24_G	63_W	1.319	0.99
480_L	485_R	1.313	0.99
27_A	154_S	1.310	0.99
301_D	315_T	1.305	0.99
347_L	351_L	1.298	0.99
441_L	474_V	1.294	0.99
17_A	59_I	1.288	0.99
260_S	471_T	1.286	0.99
417_G	465_F	1.282	0.99
313_Y	334_N	1.260	0.99
53_P	57_A	1.258	0.99
60_G	109_A	1.252	0.99
377_A	380_I	1.247	0.99
21_G	66_G	1.244	0.99
155_Q	172_I	1.243	0.99
56_S	113_S	1.240	0.99
129_P	174_F	1.236	0.99
129_P	178_M	1.226	0.99
17_A	47_L	1.223	0.99
22_A	26_L	1.219	0.99
14_L	58_A	1.211	0.99
454_P	477_T	1.210	0.99
162_G	165_P	1.207	0.99
451_V	474_V	1.205	0.99
285_D	289_R	1.199	0.99
162_G	209_R	1.198	0.99
299_I	317_I	1.196	0.99
208_L	213_W	1.183	0.99
18_L	66_G	1.176	0.99
28_F	67_L	1.170	0.99
77_V	419_S	1.168	0.99
148_W	424_Q	1.168	0.99
46_A	187_L	1.164	0.99
24_G	151_F	1.162	0.99
208_L	211_I	1.161	0.99
166_I	208_L	1.160	0.99
264_I	408_L	1.158	0.99
106_G	110_G	1.157	0.99
458_I	461_M	1.156	0.99
31_Y	420_I	1.150	0.98
406_Y	441_L	1.148	0.98
161_K	431_M	1.139	0.98
439_P	474_V	1.132	0.98
480_L	484_A	1.125	0.98
35_P	39_I	1.123	0.98
45_Q	128_A	1.121	0.98
51_R	55_Q	1.121	0.98
296_V	408_L	1.116	0.98
404_T	436_L	1.115	0.98
47_L	59_I	1.105	0.98
460_A	472_T	1.103	0.98
380_I	405_D	1.103	0.98
320_G	323_A	1.103	0.98
233_Q	236_K	1.103	0.98
162_G	434_L	1.102	0.98
439_P	477_T	1.102	0.98
348_E	352_R	1.100	0.98
236_K	268_S	1.090	0.98
94_V	97_L	1.089	0.98
268_S	300_V	1.081	0.98
54_L	58_A	1.070	0.98
241_Q	245_T	1.065	0.97
320_G	330_A	1.058	0.97
97_L	104_Y	1.057	0.97
294_S	318_T	1.057	0.97
288_L	293_S	1.057	0.97
138_L	141_W	1.054	0.97
352_R	355_A	1.049	0.97
313_Y	366_S	1.048	0.97
452_I	458_I	1.043	0.97
13_R	50_N	1.042	0.97
280_F	284_L	1.038	0.97
351_L	354_L	1.035	0.97
323_A	328_E	1.035	0.97
129_P	177_M	1.033	0.97
252_A	469_V	1.031	0.97
151_F	177_M	1.030	0.97
61_F	102_S	1.027	0.97
224_V	406_Y	1.025	0.97
98_A	102_S	1.022	0.97
104_Y	108_F	1.022	0.97
44_L	63_W	1.017	0.97
423_W	464_Q	1.017	0.97
49_F	188_V	1.014	0.97
336_N	398_D	1.012	0.97
113_S	117_P	1.006	0.96
213_W	216_P	1.005	0.96
409_T	440_L	0.997	0.96
100_Y	104_Y	0.994	0.96
150_Q	153_Y	0.993	0.96
337_H	389_E	0.993	0.96
323_A	329_S	0.992	0.96
45_Q	181_G	0.991	0.96
303_R	313_Y	0.987	0.96
190_R	193_R	0.985	0.96
269_A	297_T	0.984	0.96
316_I	386_I	0.982	0.96
438_R	480_L	0.981	0.96
221_T	476_P	0.980	0.96
69_G	98_A	0.978	0.96
162_G	208_L	0.978	0.96
13_R	59_I	0.978	0.96
163_L	167_M	0.977	0.96
69_G	95_V	0.976	0.96
227_V	265_W	0.971	0.96
73_N	420_I	0.969	0.96
43_G	47_L	0.969	0.96
147_P	391_I	0.965	0.95
262_L	296_V	0.962	0.95
100_Y	105_T	0.960	0.95
250_Y	254_A	0.953	0.95
20_F	47_L	0.952	0.95
152_G	164_A	0.951	0.95
55_Q	58_A	0.947	0.95
228_Q	446_N	0.943	0.95
172_I	175_L	0.939	0.95
411_S	464_Q	0.936	0.95
167_M	175_L	0.935	0.95
156_I	430_R	0.935	0.95
21_G	25_T	0.934	0.95
488_N	491_L	0.933	0.95
20_F	40_S	0.925	0.94
226_M	451_V	0.925	0.94
268_S	445_N	0.923	0.94
241_Q	244_N	0.922	0.94
421_G	442_R	0.919	0.94
463_P	468_E	0.916	0.94
431_M	434_L	0.915	0.94
101_L	105_T	0.913	0.94
406_Y	476_P	0.910	0.94
251_N	255_P	0.909	0.94
301_D	332_R	0.907	0.94
38_I	42_M	0.903	0.94
205_P	213_W	0.897	0.93
56_S	60_G	0.896	0.93
134_V	138_L	0.895	0.93
127_A	502_A	0.892	0.93
162_G	212_Q	0.889	0.93
227_V	469_V	0.888	0.93
374_P	381_E	0.888	0.93
223_Q	471_T	0.887	0.93
410_I	443_S	0.885	0.93
486_T	489_W	0.885	0.93
425_H	442_R	0.882	0.93
430_R	458_I	0.881	0.93
265_W	284_L	0.881	0.93
165_P	482_P	0.881	0.93
352_R	358_F	0.879	0.93
58_A	62_C	0.879	0.93
385_A	390_I	0.877	0.93
61_F	65_F	0.875	0.92
200_V	204_L	0.874	0.92
250_Y	283_A	0.873	0.92
57_A	61_F	0.870	0.92
107_L	110_G	0.868	0.92
42_M	187_L	0.865	0.92
134_V	495_T	0.864	0.92
413_D	421_G	0.856	0.92
156_I	161_K	0.853	0.91
262_L	406_Y	0.850	0.91
150_Q	173_N	0.847	0.91
338_L	388_Y	0.847	0.91
254_A	290_D	0.845	0.91
42_M	183_L	0.842	0.91
39_I	42_M	0.841	0.91
441_L	451_V	0.841	0.91
28_F	154_S	0.841	0.91
248_I	252_A	0.840	0.91
24_G	67_L	0.839	0.91
130_A	134_V	0.838	0.91
49_F	124_V	0.838	0.91
382_L	408_L	0.835	0.91
34_W	158_G	0.834	0.91
409_T	442_R	0.833	0.90
94_V	98_A	0.831	0.90
61_F	106_G	0.829	0.90
427_Q	430_R	0.829	0.90
347_L	350_I	0.828	0.90
134_V	498_F	0.828	0.90
129_P	133_Q	0.824	0.90
108_F	135_T	0.824	0.90
93_L	101_L	0.824	0.90
155_Q	160_L	0.823	0.90
206_F	209_R	0.822	0.90
235_L	241_Q	0.822	0.90
27_A	40_S	0.819	0.90
266_P	414_A	0.819	0.90
163_L	205_P	0.818	0.90
53_P	114_R	0.817	0.90
261_S	294_S	0.816	0.90
333_Y	368_G	0.815	0.89
303_R	311_D	0.813	0.89
439_P	451_V	0.811	0.89
76_Y	87_G	0.809	0.89
311_D	366_S	0.807	0.89
182_L	198_A	0.807	0.89
245_T	271_T	0.805	0.89
267_E	387_C	0.805	0.89
113_S	116_W	0.805	0.89
129_P	181_G	0.804	0.89
320_G	328_E	0.801	0.89
128_A	177_M	0.800	0.89
248_I	251_N	0.800	0.89
245_T	414_A	0.797	0.88
221_T	475_T	0.796	0.88
139_R	145_G	0.795	0.88
425_H	429_A	0.795	0.88
413_D	422_P	0.795	0.88
441_L	449_T	0.792	0.88
41_L	180_S	0.791	0.88
99_A	102_S	0.790	0.88
268_S	415_W	0.789	0.88
204_L	208_L	0.788	0.88
355_A	358_F	0.788	0.88
504_L	507_L	0.787	0.88
196_V	200_V	0.787	0.88
499_G	503_V	0.787	0.88
229_G	449_T	0.786	0.88
251_N	467_R	0.785	0.88
162_G	172_I	0.785	0.88
24_G	27_A	0.782	0.87
76_Y	90_N	0.779	0.87
397_R	436_L	0.779	0.87
156_I	431_M	0.774	0.87
108_F	128_A	0.774	0.87
131_L	498_F	0.773	0.87
342_G	416_F	0.772	0.87
245_T	249_Y	0.771	0.87
405_D	478_T	0.770	0.87
377_A	382_L	0.770	0.87
199_V	203_A	0.769	0.87
388_Y	417_G	0.765	0.86
72_I	149_L	0.764	0.86
181_G	185_L	0.763	0.86
172_I	431_M	0.763	0.86
222_I	382_L	0.761	0.86
226_M	472_T	0.760	0.86
415_W	442_R	0.757	0.86
462_I	470_L	0.756	0.86
111_V	114_R	0.753	0.85
41_L	151_F	0.753	0.85
148_W	417_G	0.753	0.85
22_A	70_S	0.750	0.85
75_V	269_A	0.749	0.85
116_W	127_A	0.749	0.85
160_L	179_V	0.748	0.85
233_Q	237_W	0.747	0.85
301_D	313_Y	0.747	0.85
479_G	482_P	0.747	0.85
233_Q	415_W	0.745	0.85
96_L	100_Y	0.745	0.85
223_Q	260_S	0.744	0.85
393_G	483_Y	0.743	0.85
73_N	419_S	0.742	0.85
49_F	184_A	0.741	0.85
396_V	407_L	0.737	0.84
108_F	112_L	0.735	0.84
264_I	441_L	0.734	0.84
492_W	496_A	0.730	0.84
235_L	238_D	0.730	0.84
422_P	448_I	0.730	0.84
197_V	286_G	0.728	0.83
156_I	427_Q	0.727	0.83
162_G	213_W	0.726	0.83
170_E	491_L	0.725	0.83
486_T	490_P	0.725	0.83
490_P	494_L	0.725	0.83
345_V	352_R	0.723	0.83
108_F	131_L	0.722	0.83
64_G	106_G	0.721	0.83
289_R	322_G	0.721	0.83
224_V	262_L	0.718	0.83
97_L	105_T	0.718	0.83
207_P	210_Y	0.717	0.83
236_K	445_N	0.717	0.83
357_F	360_L	0.715	0.82
390_I	442_R	0.715	0.82
336_N	371_I	0.714	0.82
273_L	300_V	0.714	0.82
481_T	487_G	0.713	0.82
356_P	360_L	0.712	0.82
130_A	495_T	0.712	0.82
111_V	131_L	0.709	0.82
223_Q	261_S	0.707	0.82
244_N	248_I	0.704	0.81
171_A	175_L	0.701	0.81
150_Q	393_G	0.698	0.81
236_K	269_A	0.698	0.81
130_A	174_F	0.697	0.81
153_Y	169_V	0.696	0.81
45_Q	184_A	0.693	0.80
246_L	280_F	0.692	0.80
374_P	404_T	0.692	0.80
65_F	99_A	0.691	0.80
336_N	370_Y	0.691	0.80
151_F	173_N	0.691	0.80
220_K	476_P	0.688	0.80
132_W	136_E	0.687	0.80
296_V	384_A	0.687	0.80
376_S	379_G	0.684	0.79
79_I	416_F	0.682	0.79
230_D	412_N	0.681	0.79
38_I	43_G	0.680	0.79
223_Q	259_K	0.678	0.79
262_L	408_L	0.678	0.79
125_A	182_L	0.677	0.79
147_P	392_L	0.676	0.79
415_W	445_N	0.676	0.79
263_I	293_S	0.676	0.79
55_Q	59_I	0.675	0.79
59_I	62_C	0.672	0.78
161_K	165_P	0.671	0.78
15_L	19_L	0.671	0.78
385_A	409_T	0.670	0.78
459_Q	472_T	0.670	0.78
238_D	241_Q	0.670	0.78
186_A	189_K	0.668	0.78
268_S	411_S	0.667	0.78
333_Y	386_I	0.666	0.78
252_A	256_L	0.665	0.78
130_A	498_F	0.665	0.78
281_L	317_I	0.664	0.77
390_I	429_A	0.664	0.77
205_P	210_Y	0.663	0.77
143_L	347_L	0.663	0.77
73_N	77_V	0.661	0.77
409_T	444_T	0.661	0.77
257_M	263_I	0.660	0.77
179_V	202_F	0.659	0.77
48_T	112_L	0.659	0.77
383_T	396_V	0.657	0.77
381_E	384_A	0.657	0.77
388_Y	442_R	0.656	0.77
110_G	113_S	0.656	0.77
214_F	217_Q	0.655	0.77
100_Y	103_L	0.654	0.76
128_A	181_G	0.654	0.76
224_V	451_V	0.653	0.76
227_V	263_I	0.653	0.76
390_I	425_H	0.652	0.76
27_A	35_P	0.650	0.76
418_K	465_F	0.650	0.76
468_E	471_T	0.648	0.76
63_W	105_T	0.647	0.76
126_I	178_M	0.646	0.76
199_V	210_Y	0.646	0.76
353_P	359_D	0.646	0.76
430_R	434_L	0.645	0.75
90_N	94_V	0.645	0.75
83_G	86_P	0.645	0.75
114_R	117_P	0.644	0.75
79_I	409_T	0.642	0.75
23_C	40_S	0.642	0.75
267_E	335_K	0.642	0.75
422_P	446_N	0.642	0.75
314_N	416_F	0.640	0.75
162_G	437_A	0.640	0.75
167_M	172_I	0.640	0.75
133_Q	491_L	0.639	0.75
182_L	186_A	0.639	0.75
232_P	235_L	0.638	0.75
46_A	49_F	0.638	0.75
289_R	323_A	0.637	0.75
391_I	428_M	0.637	0.75
124_V	129_P	0.636	0.74
198_A	202_F	0.636	0.74
166_I	209_R	0.635	0.74
114_R	118_K	0.634	0.74
322_G	328_E	0.633	0.74
75_V	94_V	0.632	0.74
233_Q	412_N	0.631	0.74
104_Y	139_R	0.630	0.74
439_P	476_P	0.630	0.74
251_N	254_A	0.629	0.74
300_V	312_T	0.629	0.74
230_D	446_N	0.629	0.74
314_N	415_W	0.628	0.73
46_A	50_N	0.628	0.73
354_L	358_F	0.627	0.73
150_Q	169_V	0.625	0.73
137_F	488_N	0.625	0.73
79_I	83_G	0.625	0.73
407_L	436_L	0.625	0.73
454_P	475_T	0.625	0.73
415_W	425_H	0.624	0.73
79_I	93_L	0.622	0.73
303_R	309_R	0.621	0.73
194_P	198_A	0.620	0.73
148_W	388_Y	0.618	0.72
105_T	132_W	0.618	0.72
23_C	196_V	0.617	0.72
222_I	262_L	0.615	0.72
96_L	130_A	0.615	0.72
205_P	214_F	0.614	0.72
491_L	494_L	0.614	0.72
414_A	446_N	0.614	0.72
227_V	371_I	0.613	0.72
449_T	470_L	0.612	0.72
231_I	445_N	0.612	0.72
130_A	494_L	0.611	0.71
154_S	172_I	0.610	0.71
449_T	463_P	0.610	0.71
403_D	438_R	0.608	0.71
132_W	151_F	0.606	0.71
356_P	359_D	0.606	0.71
233_Q	365_F	0.605	0.71
148_W	428_M	0.603	0.70
78_S	419_S	0.603	0.70
29_S	32_D	0.601	0.70
204_L	486_T	0.600	0.70
66_G	70_S	0.600	0.70
245_T	248_I	0.600	0.70
419_S	465_F	0.599	0.70
409_T	429_A	0.599	0.70
202_F	457_E	0.596	0.70
125_A	181_G	0.596	0.70
163_L	208_L	0.595	0.69
117_P	199_V	0.595	0.69
72_I	97_L	0.595	0.69
139_R	233_Q	0.594	0.69
249_Y	265_W	0.594	0.69
44_L	48_T	0.593	0.69
339_V	386_I	0.593	0.69
20_F	63_W	0.592	0.69
246_L	270_I	0.591	0.69
426_F	440_L	0.590	0.69
323_A	493_V	0.590	0.69
169_V	431_M	0.590	0.69
192_W	196_V	0.589	0.69
201_L	205_P	0.588	0.69
287_E	290_D	0.588	0.69
349_S	353_P	0.588	0.69
286_G	323_A	0.587	0.68
207_P	211_I	0.587	0.68
384_A	410_I	0.585	0.68
417_G	422_P	0.584	0.68
271_T	445_N	0.583	0.68
484_A	488_N	0.582	0.68
438_R	477_T	0.582	0.68
155_Q	158_G	0.582	0.68
443_S	470_L	0.582	0.68
260_S	263_I	0.581	0.68
352_R	360_L	0.580	0.67
27_A	44_L	0.580	0.67
19_L	203_A	0.579	0.67
234_S	238_D	0.578	0.67
36_A	40_S	0.578	0.67
500_F	504_L	0.578	0.67
401_R	480_L	0.577	0.67
493_V	500_F	0.577	0.67
195_L	204_L	0.577	0.67
140_G	170_E	0.576	0.67
345_V	358_F	0.576	0.67
48_T	59_I	0.575	0.67
176_L	180_S	0.574	0.67
268_S	314_N	0.574	0.67
463_P	466_T	0.573	0.67
316_I	407_L	0.573	0.67
264_I	410_I	0.572	0.66
265_W	270_I	0.571	0.66
282_K	286_G	0.568	0.66
294_S	320_G	0.567	0.66
247_K	250_Y	0.567	0.66
66_G	71_G	0.567	0.66
231_I	236_K	0.566	0.66
412_N	442_R	0.566	0.66
317_I	332_R	0.565	0.65
251_N	496_A	0.564	0.65
48_T	106_G	0.564	0.65
24_G	37_A	0.561	0.65
459_Q	496_A	0.559	0.65
76_Y	91_I	0.559	0.65
265_W	269_A	0.558	0.65
195_L	199_V	0.558	0.65
196_V	494_L	0.558	0.65
422_P	444_T	0.557	0.64
164_A	428_M	0.556	0.64
229_G	245_T	0.556	0.64
202_F	209_R	0.555	0.64
389_E	422_P	0.555	0.64
134_V	486_T	0.554	0.64
318_T	331_D	0.554	0.64
137_F	492_W	0.554	0.64
140_G	150_Q	0.553	0.64
145_G	340_P	0.553	0.64
393_G	413_D	0.553	0.64
455_Q	459_Q	0.552	0.64
416_F	422_P	0.552	0.64
392_L	421_G	0.552	0.64
202_F	205_P	0.551	0.64
102_S	106_G	0.550	0.63
170_E	173_N	0.550	0.63
426_F	448_I	0.550	0.63
228_Q	412_N	0.549	0.63
39_I	180_S	0.549	0.63
267_E	314_N	0.549	0.63
193_R	197_V	0.548	0.63
252_A	467_R	0.546	0.63
79_I	358_F	0.545	0.63
353_P	358_F	0.544	0.63
156_I	434_L	0.543	0.62
404_T	438_R	0.543	0.62
444_T	449_T	0.542	0.62
68_F	102_S	0.542	0.62
262_L	318_T	0.542	0.62
336_N	392_L	0.542	0.62
58_A	61_F	0.542	0.62
357_F	362_M	0.541	0.62
21_G	424_Q	0.541	0.62
246_L	249_Y	0.541	0.62
57_A	103_L	0.540	0.62
264_I	302_A	0.539	0.62
361_P	364_S	0.538	0.62
184_A	395_Q	0.537	0.62
90_N	93_L	0.537	0.62
433_A	454_P	0.537	0.62
17_A	36_A	0.536	0.61
78_S	411_S	0.535	0.61
208_L	215_T	0.534	0.61
275_I	317_I	0.533	0.61
396_V	436_L	0.533	0.61
222_I	406_Y	0.532	0.61
20_F	180_S	0.532	0.61
227_V	253_T	0.531	0.61
351_L	357_F	0.530	0.61
237_W	241_Q	0.530	0.61
72_I	101_L	0.530	0.61
403_D	436_L	0.529	0.60
370_Y	374_P	0.529	0.60
265_W	413_D	0.529	0.60
148_W	342_G	0.529	0.60
96_L	486_T	0.528	0.60
130_A	491_L	0.528	0.60
231_I	248_I	0.528	0.60
145_G	233_Q	0.527	0.60
146_F	388_Y	0.527	0.60
249_Y	268_S	0.526	0.60
228_Q	424_Q	0.523	0.60
358_F	362_M	0.523	0.60
490_P	493_V	0.522	0.59
210_Y	213_W	0.522	0.59
253_T	287_E	0.522	0.59
497_L	501_A	0.521	0.59
265_W	393_G	0.521	0.59
493_V	497_L	0.521	0.59
268_S	412_N	0.521	0.59
237_W	245_T	0.521	0.59
97_L	100_Y	0.520	0.59
174_F	423_W	0.518	0.59
98_A	318_T	0.518	0.59
275_I	302_A	0.517	0.59
227_V	249_Y	0.516	0.59
41_L	196_V	0.516	0.59
230_D	466_T	0.515	0.58
203_A	207_P	0.515	0.58
39_I	43_G	0.514	0.58
302_A	308_N	0.513	0.58
343_E	346_P	0.513	0.58
498_F	501_A	0.513	0.58
125_A	178_M	0.512	0.58
339_V	421_G	0.510	0.58
375_L	378_N	0.509	0.58
25_T	420_I	0.508	0.57
74_W	148_W	0.508	0.57
398_D	402_P	0.508	0.57
78_S	397_R	0.506	0.57
410_I	445_N	0.506	0.57
417_G	464_Q	0.506	0.57
203_A	208_L	0.506	0.57
146_F	266_P	0.506	0.57
74_W	424_Q	0.505	0.57
282_K	501_A	0.505	0.57
215_T	473_N	0.504	0.57
345_V	353_P	0.504	0.57
341_F	416_F	0.503	0.57
409_T	421_G	0.503	0.57
87_G	94_V	0.503	0.57
68_F	75_V	0.502	0.57
345_V	359_D	0.502	0.57
227_V	255_P	0.501	0.56
204_L	210_Y	0.501	0.56
76_Y	94_V	0.500	0.56
249_Y	253_T	0.500	0.56

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1uf5A	4	0.5059	100	0.64	Contact Map
2w1vA	2	0.4805	100	0.666	Contact Map
3p8kA	2	0.4746	100	0.667	Contact Map
2e11A	2	0.4629	100	0.671	Contact Map
4izuA	2	0.4434	100	0.676	Contact Map
4hg5A	2	0.4902	100	0.676	Contact Map
1f89A	2	0.4785	100	0.677	Contact Map
3ivzA	2	0.4531	100	0.677	Contact Map
1emsA	3	0.5117	100	0.681	Contact Map
4f4hA	2	0.5059	100	0.681	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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