CADC - ECOLI - GREMLIN Contacts

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CADC - Transcriptional activator CadC

UniProt:	P23890	Sequences: MQQPVVRVGEWLVTPSINQISRNGRQLTLEPRLIDLLVFFAQHSGEVLSRDELIDNVWKRSIVTNHVVTQSISELRKSLKDNDEDSPVYIATVPKRGYKLMVPVIWYSEEEGEEIMLSSPPPIPEAVPATDSPSHSLNIQNTATPPEQSPVKSKRFTTFWVWFFFLLSLGICVALVAFSSLDTRLPMSKSRILLNPRDIDINMVNKSCNSWSSPYQLSYAIGVGDLVATSLNTFSTFMVHDKINYNIDEPSSSGKTLSIAFVNQRQYRAQQCFMSIKLVDNADGSTMLDKRYVITNGNQLAIQNDLLESLSKALNQPWPQRMQETLQKILPHRGALLTNFYQAHDYLLHGDDKSLNRASELLGEIVQSSPEFTYARAEKALVDIVRHSQHPLDEKQLAALNTEIDNIVTLPELNNLSIIYQIKAVSALVKGKTDESYQAINTGIDLEMSWLNYVLLGKVYEMKGMNREAADAYLTAFNLRPGANTLYWIENGIFQTSVPYVVPYLDKFLASE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10133
Length:	512 (423)
Sequences:	1348 (1249)
Seq/√Len:	60.7

ECOLI - CADC YGEH

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
432_K	435_E	7.335	1.00
465_M	468_E	6.637	1.00
457_G	473_Y	4.791	1.00
424_A	440_I	4.670	1.00
388_S	399_A	3.772	1.00
39_F	53_L	3.290	1.00
131_D	138_N	3.282	1.00
354_S	357_R	3.094	1.00
376_R	403_E	2.745	1.00
258_S	263_N	2.715	1.00
41_A	100_L	2.709	1.00
257_L	267_Y	2.676	1.00
36_L	57_V	2.575	1.00
167_L	173_V	2.574	1.00
420_Y	439_A	2.442	1.00
131_D	137_L	2.408	1.00
170_G	173_V	2.399	1.00
460_Y	465_M	2.387	1.00
127_V	130_T	2.337	1.00
257_L	263_N	2.320	1.00
437_Y	456_L	2.277	1.00
33_L	71_S	2.229	1.00
43_H	46_E	2.223	1.00
453_Y	472_A	2.218	1.00
359_S	363_G	2.173	1.00
167_L	170_G	2.172	1.00
437_Y	463_K	2.156	1.00
380_A	404_I	2.142	1.00
30_E	71_S	2.139	1.00
257_L	260_A	2.134	1.00
340_F	343_A	2.132	1.00
167_L	174_A	2.117	1.00
256_T	263_N	2.110	1.00
260_A	263_N	2.109	1.00
19_Q	26_Q	2.068	1.00
198_D	203_M	1.993	1.00
437_Y	441_N	1.982	1.00
134_S	137_L	1.963	1.00
134_S	138_N	1.957	1.00
200_D	203_M	1.940	1.00
231_L	236_T	1.930	1.00
263_N	268_R	1.910	1.00
71_S	74_E	1.909	1.00
43_H	52_E	1.900	1.00
401_N	427_A	1.899	1.00
130_T	137_L	1.861	1.00
358_A	362_L	1.859	1.00
262_V	267_Y	1.812	1.00
33_L	74_E	1.792	1.00
275_S	279_V	1.779	0.99
210_S	213_S	1.775	0.99
130_T	138_N	1.771	0.99
343_A	362_L	1.759	0.99
44_S	48_L	1.742	0.99
53_L	68_V	1.738	0.99
359_S	379_K	1.713	0.99
70_Q	74_E	1.703	0.99
167_L	172_C	1.690	0.99
67_V	70_Q	1.678	0.99
174_A	204_V	1.676	0.99
67_V	71_S	1.662	0.99
261_F	265_R	1.640	0.99
256_T	267_Y	1.621	0.99
216_Q	219_Y	1.621	0.99
272_C	275_S	1.621	0.99
32_R	57_V	1.618	0.99
169_L	174_A	1.618	0.99
460_Y	472_A	1.612	0.99
39_F	57_V	1.605	0.99
437_Y	459_V	1.605	0.99
199_I	203_M	1.601	0.99
263_N	266_Q	1.597	0.99
401_N	405_D	1.591	0.99
189_K	200_D	1.587	0.99
66_H	69_T	1.580	0.99
421_Q	455_L	1.578	0.99
170_G	174_A	1.576	0.99
39_F	43_H	1.570	0.99
34_I	63_V	1.561	0.99
417_S	443_G	1.558	0.99
248_D	251_S	1.535	0.98
50_R	65_N	1.535	0.98
108_S	112_G	1.531	0.98
199_I	202_N	1.522	0.98
132_S	135_H	1.519	0.98
255_K	263_N	1.515	0.98
196_P	203_M	1.508	0.98
30_E	33_L	1.504	0.98
257_L	261_F	1.484	0.98
260_A	267_Y	1.483	0.98
362_L	378_E	1.481	0.98
373_T	411_P	1.473	0.98
30_E	70_Q	1.471	0.98
114_E	118_S	1.463	0.98
288_L	292_Y	1.459	0.98
427_A	435_E	1.456	0.98
262_V	266_Q	1.453	0.98
29_L	78_S	1.445	0.98
165_F	172_C	1.430	0.98
460_Y	468_E	1.430	0.98
199_I	204_V	1.423	0.97
424_A	456_L	1.399	0.97
69_T	72_I	1.398	0.97
161_V	164_F	1.397	0.97
245_Y	248_D	1.396	0.97
263_N	267_Y	1.384	0.97
47_V	92_T	1.379	0.97
369_S	372_F	1.376	0.97
66_H	70_Q	1.362	0.97
259_I	265_R	1.361	0.97
127_V	131_D	1.356	0.97
131_D	134_S	1.347	0.96
43_H	100_L	1.338	0.96
189_K	192_I	1.329	0.96
404_I	422_I	1.326	0.96
47_V	96_R	1.318	0.96
189_K	193_L	1.316	0.96
456_L	460_Y	1.311	0.96
55_D	60_R	1.310	0.96
203_M	206_K	1.307	0.96
239_V	243_I	1.302	0.96
262_V	265_R	1.301	0.96
427_A	432_K	1.300	0.96
453_Y	475_T	1.298	0.96
459_V	463_K	1.292	0.95
34_I	38_V	1.286	0.95
440_I	456_L	1.282	0.95
300_L	303_Q	1.280	0.95
435_E	438_Q	1.275	0.95
67_V	74_E	1.272	0.95
196_P	204_V	1.267	0.95
338_T	341_Y	1.260	0.95
91_A	101_M	1.257	0.95
216_Q	220_A	1.247	0.94
330_L	334_G	1.245	0.94
256_T	261_F	1.244	0.94
254_G	257_L	1.241	0.94
286_T	289_D	1.236	0.94
405_D	423_K	1.236	0.94
169_L	173_V	1.235	0.94
280_D	283_D	1.235	0.94
80_K	83_D	1.232	0.94
42_Q	56_N	1.225	0.94
379_K	403_E	1.220	0.94
173_V	176_V	1.220	0.94
198_D	202_N	1.212	0.94
404_I	424_A	1.206	0.93
295_T	307_L	1.205	0.93
247_I	250_P	1.205	0.93
440_I	455_L	1.201	0.93
337_L	340_F	1.197	0.93
338_T	346_Y	1.192	0.93
170_G	181_L	1.187	0.93
255_K	262_V	1.183	0.93
93_V	99_K	1.183	0.93
248_D	252_S	1.181	0.93
290_K	294_I	1.179	0.93
30_E	74_E	1.176	0.93
199_I	206_K	1.176	0.93
254_G	263_N	1.168	0.92
343_A	452_N	1.160	0.92
76_R	98_Y	1.153	0.92
441_N	445_D	1.152	0.92
231_L	234_F	1.148	0.92
358_A	368_S	1.148	0.92
189_K	203_M	1.144	0.91
196_P	202_N	1.137	0.91
178_F	182_D	1.125	0.91
276_I	285_S	1.120	0.91
164_F	169_L	1.119	0.91
173_V	181_L	1.118	0.90
354_S	358_A	1.117	0.90
190_S	199_I	1.116	0.90
216_Q	231_L	1.116	0.90
169_L	172_C	1.109	0.90
206_K	210_S	1.104	0.90
198_D	204_V	1.102	0.90
160_W	164_F	1.099	0.90
277_K	281_N	1.098	0.90
91_A	99_K	1.089	0.89
73_S	77_K	1.086	0.89
363_G	399_A	1.085	0.89
383_D	399_A	1.085	0.89
172_C	176_V	1.082	0.89
276_I	283_D	1.077	0.89
220_A	234_F	1.075	0.89
175_L	179_S	1.072	0.89
257_L	262_V	1.069	0.88
160_W	163_F	1.066	0.88
276_I	279_V	1.064	0.88
337_L	341_Y	1.061	0.88
32_R	67_V	1.048	0.87
34_I	57_V	1.048	0.87
119_S	123_I	1.047	0.87
401_N	430_K	1.046	0.87
296_N	307_L	1.045	0.87
343_A	347_L	1.044	0.87
331_P	336_L	1.037	0.87
188_S	191_R	1.034	0.87
193_L	198_D	1.030	0.86
283_D	286_T	1.028	0.86
295_T	314_L	1.023	0.86
471_D	475_T	1.022	0.86
281_N	285_S	1.019	0.86
259_I	266_Q	1.019	0.86
54_I	62_I	1.016	0.86
47_V	97_G	1.011	0.85
420_Y	446_L	1.011	0.85
165_F	170_G	1.009	0.85
442_T	445_D	1.008	0.85
343_A	361_L	1.002	0.85
75_L	90_I	1.001	0.85
190_S	203_M	1.001	0.85
359_S	382_V	0.999	0.85
238_M	243_I	0.995	0.85
450_W	480_R	0.994	0.84
314_L	317_P	0.991	0.84
119_S	124_P	0.986	0.84
41_A	44_S	0.986	0.84
165_F	173_V	0.984	0.84
230_S	233_T	0.979	0.84
33_L	36_L	0.975	0.83
200_D	204_V	0.972	0.83
359_S	386_R	0.969	0.83
220_A	232_N	0.967	0.83
257_L	265_R	0.966	0.83
376_R	406_N	0.966	0.83
427_A	439_A	0.964	0.83
363_G	379_K	0.964	0.83
437_Y	460_Y	0.962	0.82
49_S	52_E	0.960	0.82
383_D	403_E	0.959	0.82
461_E	473_Y	0.952	0.82
308_E	312_K	0.951	0.82
401_N	432_K	0.950	0.82
236_T	243_I	0.949	0.82
278_L	282_A	0.949	0.82
364_E	367_Q	0.946	0.81
59_K	67_V	0.945	0.81
118_S	121_P	0.941	0.81
189_K	199_I	0.941	0.81
282_A	286_T	0.939	0.81
94_P	97_G	0.935	0.81
249_E	252_S	0.934	0.81
261_F	266_Q	0.933	0.80
109_E	113_E	0.932	0.80
401_N	426_S	0.931	0.80
257_L	268_R	0.929	0.80
81_D	88_V	0.928	0.80
340_F	372_F	0.927	0.80
454_V	473_Y	0.927	0.80
441_N	456_L	0.926	0.80
343_A	346_Y	0.925	0.80
258_S	266_Q	0.924	0.80
401_N	423_K	0.923	0.80
338_T	342_Q	0.922	0.80
172_C	181_L	0.921	0.80
440_I	459_V	0.920	0.80
279_V	284_G	0.919	0.79
231_L	239_V	0.917	0.79
311_S	314_L	0.909	0.79
234_F	239_V	0.908	0.79
174_A	181_L	0.906	0.79
170_G	179_S	0.901	0.78
162_W	180_S	0.901	0.78
450_W	476_A	0.901	0.78
289_D	303_Q	0.895	0.78
287_M	307_L	0.895	0.78
285_S	288_L	0.891	0.77
170_G	177_A	0.889	0.77
226_L	231_L	0.881	0.77
116_M	119_S	0.880	0.76
260_A	265_R	0.879	0.76
382_V	386_R	0.877	0.76
362_L	375_A	0.877	0.76
276_I	281_N	0.876	0.76
32_R	70_Q	0.876	0.76
460_Y	463_K	0.872	0.76
319_P	326_L	0.868	0.75
254_G	258_S	0.868	0.75
358_A	375_A	0.863	0.75
94_P	98_Y	0.862	0.75
324_E	328_K	0.861	0.75
307_L	314_L	0.860	0.75
186_P	189_K	0.859	0.75
426_S	430_K	0.853	0.74
276_I	280_D	0.850	0.74
36_L	48_L	0.848	0.74
199_I	205_N	0.847	0.74
423_K	427_A	0.845	0.73
226_L	229_T	0.845	0.73
208_C	216_Q	0.845	0.73
43_H	73_S	0.843	0.73
132_S	138_N	0.843	0.73
167_L	177_A	0.842	0.73
401_N	408_V	0.839	0.73
322_M	325_T	0.838	0.73
468_E	471_D	0.834	0.73
170_G	175_L	0.834	0.73
165_F	177_A	0.833	0.72
406_N	409_T	0.832	0.72
256_T	265_R	0.832	0.72
288_L	291_R	0.831	0.72
331_P	338_T	0.830	0.72
335_A	344_H	0.830	0.72
185_L	189_K	0.830	0.72
72_I	98_Y	0.826	0.72
172_C	175_L	0.823	0.72
433_T	459_V	0.820	0.71
335_A	347_L	0.815	0.71
258_S	265_R	0.815	0.71
366_V	376_R	0.814	0.71
424_A	455_L	0.812	0.70
249_E	253_S	0.811	0.70
59_K	63_V	0.809	0.70
163_F	174_A	0.809	0.70
40_F	48_L	0.804	0.70
43_H	56_N	0.802	0.70
307_L	311_S	0.799	0.69
257_L	266_Q	0.798	0.69
270_Q	273_F	0.797	0.69
236_T	239_V	0.796	0.69
335_A	339_N	0.794	0.69
295_T	299_Q	0.793	0.69
305_D	309_S	0.791	0.68
259_I	263_N	0.790	0.68
89_Y	102_V	0.789	0.68
408_V	420_Y	0.788	0.68
133_P	138_N	0.784	0.68
205_N	216_Q	0.777	0.67
380_A	426_S	0.777	0.67
358_A	361_L	0.777	0.67
126_A	131_D	0.775	0.67
228_A	233_T	0.774	0.67
213_S	216_Q	0.774	0.67
196_P	201_I	0.772	0.67
336_L	343_A	0.771	0.66
242_K	245_Y	0.767	0.66
50_R	54_I	0.767	0.66
127_V	134_S	0.766	0.66
365_I	375_A	0.763	0.66
260_A	264_Q	0.763	0.66
133_P	137_L	0.759	0.65
473_Y	477_F	0.758	0.65
471_D	474_L	0.756	0.65
364_E	368_S	0.756	0.65
213_S	228_A	0.755	0.65
398_A	402_T	0.753	0.65
83_D	89_Y	0.752	0.65
254_G	268_R	0.751	0.64
308_E	311_S	0.750	0.64
458_K	462_M	0.748	0.64
365_I	368_S	0.747	0.64
361_L	364_E	0.745	0.64
31_P	67_V	0.744	0.64
339_N	345_D	0.744	0.64
233_T	239_V	0.743	0.64
174_A	178_F	0.741	0.63
175_L	180_S	0.741	0.63
281_N	284_G	0.737	0.63
296_N	308_E	0.736	0.63
310_L	314_L	0.735	0.63
65_N	96_R	0.735	0.63
276_I	288_L	0.735	0.63
309_S	314_L	0.733	0.63
282_A	285_S	0.731	0.62
75_L	97_G	0.730	0.62
292_Y	307_L	0.728	0.62
339_N	361_L	0.726	0.62
127_V	137_L	0.726	0.62
64_T	69_T	0.724	0.62
250_P	253_S	0.724	0.62
279_V	286_T	0.724	0.62
22_R	25_R	0.723	0.61
20_I	30_E	0.721	0.61
201_I	204_V	0.720	0.61
260_A	266_Q	0.719	0.61
383_D	388_S	0.718	0.61
405_D	445_D	0.717	0.61
21_S	26_Q	0.717	0.61
19_Q	22_R	0.715	0.61
126_A	135_H	0.713	0.60
27_L	55_D	0.712	0.60
258_S	264_Q	0.711	0.60
323_Q	326_L	0.711	0.60
123_I	138_N	0.711	0.60
222_G	228_A	0.710	0.60
303_Q	307_L	0.710	0.60
33_L	67_V	0.709	0.60
455_L	460_Y	0.709	0.60
31_P	45_G	0.708	0.60
271_Q	282_A	0.704	0.59
428_L	433_T	0.703	0.59
219_Y	232_N	0.701	0.59
335_A	368_S	0.701	0.59
64_T	67_V	0.701	0.59
78_S	137_L	0.700	0.59
255_K	267_Y	0.700	0.59
426_S	458_K	0.698	0.59
172_C	177_A	0.698	0.59
443_G	452_N	0.697	0.59
170_G	176_V	0.696	0.59
111_E	115_I	0.696	0.59
333_R	336_L	0.696	0.59
186_P	190_S	0.695	0.58
230_S	239_V	0.693	0.58
259_I	267_Y	0.691	0.58
32_R	35_D	0.691	0.58
221_I	232_N	0.691	0.58
21_S	75_L	0.690	0.58
474_L	478_N	0.690	0.58
216_Q	230_S	0.689	0.58
119_S	125_E	0.686	0.57
34_I	65_N	0.685	0.57
194_L	203_M	0.685	0.57
342_Q	347_L	0.684	0.57
443_G	448_M	0.684	0.57
57_V	69_T	0.684	0.57
330_L	338_T	0.683	0.57
258_S	267_Y	0.682	0.57
76_R	97_G	0.682	0.57
35_D	70_Q	0.681	0.57
244_N	250_P	0.680	0.57
269_A	277_K	0.676	0.56
331_P	347_L	0.676	0.56
165_F	169_L	0.675	0.56
322_M	326_L	0.675	0.56
408_V	419_I	0.669	0.56
244_N	249_E	0.669	0.56
63_V	96_R	0.669	0.56
30_E	35_D	0.669	0.56
280_D	284_G	0.669	0.56
256_T	264_Q	0.669	0.56
289_D	292_Y	0.668	0.55
343_A	358_A	0.668	0.55
127_V	138_N	0.666	0.55
70_Q	99_K	0.665	0.55
189_K	206_K	0.663	0.55
216_Q	233_T	0.661	0.55
189_K	204_V	0.660	0.55
232_N	236_T	0.654	0.54
406_N	410_L	0.653	0.54
130_T	133_P	0.650	0.53
50_R	92_T	0.649	0.53
33_L	41_A	0.649	0.53
308_E	315_N	0.648	0.53
216_Q	224_G	0.646	0.53
331_P	337_L	0.645	0.53
66_H	71_S	0.643	0.53
200_D	205_N	0.643	0.53
105_I	115_I	0.643	0.53
52_E	56_N	0.642	0.53
218_S	229_T	0.642	0.53
103_P	106_W	0.639	0.52
292_Y	295_T	0.639	0.52
409_T	470_A	0.638	0.52
423_K	439_A	0.637	0.52
130_T	134_S	0.637	0.52
198_D	206_K	0.636	0.52
72_I	97_G	0.633	0.52
168_S	173_V	0.633	0.52
163_F	169_L	0.632	0.51
441_N	468_E	0.632	0.51
420_Y	442_T	0.631	0.51
261_F	267_Y	0.629	0.51
376_R	410_L	0.628	0.51
213_S	285_S	0.627	0.51
269_A	275_S	0.627	0.51
311_S	315_N	0.625	0.51
216_Q	236_T	0.625	0.51
265_R	268_R	0.624	0.51
69_T	92_T	0.623	0.50
81_D	90_I	0.623	0.50
30_E	57_V	0.622	0.50
50_R	63_V	0.620	0.50
173_V	179_S	0.620	0.50
196_P	199_I	0.620	0.50
167_L	171_I	0.619	0.50
296_N	299_Q	0.618	0.50
461_E	466_N	0.617	0.50
458_K	473_Y	0.617	0.50
79_L	159_F	0.616	0.50
288_L	303_Q	0.616	0.50
234_F	238_M	0.616	0.50
271_Q	274_M	0.615	0.50
258_S	268_R	0.615	0.50
229_T	232_N	0.615	0.50
34_I	64_T	0.614	0.49
295_T	311_S	0.613	0.49
404_I	426_S	0.613	0.49
255_K	258_S	0.613	0.49
20_I	34_I	0.612	0.49
271_Q	276_I	0.612	0.49
283_D	288_L	0.612	0.49
169_L	181_L	0.611	0.49
331_P	334_G	0.610	0.49
325_T	328_K	0.609	0.49
404_I	440_I	0.609	0.49
457_G	476_A	0.606	0.48
428_L	452_N	0.605	0.48
238_M	242_K	0.605	0.48
52_E	104_V	0.604	0.48
197_R	202_N	0.604	0.48
284_G	306_L	0.604	0.48
274_M	288_L	0.603	0.48
216_Q	229_T	0.603	0.48
450_W	479_L	0.603	0.48
93_V	96_R	0.602	0.48
427_A	430_K	0.602	0.48
236_T	241_D	0.602	0.48
39_F	56_N	0.602	0.48
238_M	241_D	0.602	0.48
245_Y	252_S	0.601	0.48
34_I	95_K	0.601	0.48
201_I	205_N	0.601	0.48
64_T	71_S	0.600	0.48
54_I	59_K	0.600	0.48
304_N	307_L	0.597	0.47
237_F	241_D	0.596	0.47
202_N	205_N	0.594	0.47
48_L	99_K	0.593	0.47
31_P	43_H	0.593	0.47
57_V	67_V	0.592	0.47
275_S	304_N	0.591	0.47
337_L	343_A	0.588	0.46
239_V	242_K	0.588	0.46
69_T	94_P	0.588	0.46
125_E	405_D	0.587	0.46
340_F	346_Y	0.586	0.46
163_F	166_L	0.581	0.46
310_L	328_K	0.579	0.45
30_E	95_K	0.578	0.45
123_I	434_D	0.578	0.45
61_S	67_V	0.577	0.45
54_I	65_N	0.574	0.45
244_N	248_D	0.574	0.45
366_V	375_A	0.573	0.45
92_T	97_G	0.572	0.45
380_A	428_L	0.572	0.45
283_D	289_D	0.570	0.44
179_S	183_T	0.570	0.44
115_I	137_L	0.570	0.44
261_F	268_R	0.570	0.44
255_K	266_Q	0.570	0.44
437_Y	440_I	0.569	0.44
167_L	181_L	0.567	0.44
275_S	280_D	0.565	0.44
190_S	198_D	0.564	0.44
216_Q	234_F	0.561	0.43
164_F	181_L	0.560	0.43
276_I	284_G	0.558	0.43
216_Q	232_N	0.558	0.43
358_A	382_V	0.557	0.43
241_D	245_Y	0.556	0.43
269_A	272_C	0.555	0.43
274_M	286_T	0.555	0.43
82_N	101_M	0.554	0.43
221_I	231_L	0.554	0.43
256_T	268_R	0.553	0.43
379_K	383_D	0.552	0.42
135_H	138_N	0.552	0.42
212_S	216_Q	0.552	0.42
90_I	100_L	0.551	0.42
309_S	315_N	0.551	0.42
331_P	345_D	0.550	0.42
377_A	422_I	0.549	0.42
342_Q	346_Y	0.549	0.42
44_S	119_S	0.547	0.42
262_V	276_I	0.547	0.42
374_Y	378_E	0.547	0.42
475_T	479_L	0.546	0.42
428_L	462_M	0.545	0.42
167_L	175_L	0.545	0.42
382_V	427_A	0.545	0.42
411_P	415_N	0.544	0.42
288_L	294_I	0.543	0.41
285_S	295_T	0.543	0.41
130_T	135_H	0.542	0.41
226_L	230_S	0.539	0.41
32_R	94_P	0.536	0.41
283_D	290_K	0.536	0.41
37_L	75_L	0.536	0.41
237_F	242_K	0.536	0.41
271_Q	280_D	0.536	0.41
276_I	282_A	0.535	0.41
404_I	419_I	0.535	0.41
456_L	472_A	0.534	0.40
264_Q	267_Y	0.534	0.40
283_D	293_V	0.533	0.40
331_P	340_F	0.532	0.40
303_Q	306_L	0.531	0.40
126_A	138_N	0.530	0.40
211_W	217_L	0.530	0.40
337_L	347_L	0.530	0.40
314_L	318_W	0.530	0.40
274_M	279_V	0.529	0.40
404_I	411_P	0.529	0.40
320_Q	323_Q	0.527	0.40
47_V	101_M	0.524	0.39
168_S	172_C	0.524	0.39
301_A	305_D	0.523	0.39
229_T	234_F	0.523	0.39
159_F	442_T	0.522	0.39
194_L	199_I	0.522	0.39
284_G	299_Q	0.521	0.39
193_L	202_N	0.521	0.39
275_S	285_S	0.521	0.39
383_D	386_R	0.520	0.39
226_L	232_N	0.519	0.39
421_Q	470_A	0.518	0.39
169_L	175_L	0.518	0.39
52_E	63_V	0.517	0.39
434_D	439_A	0.517	0.39
257_L	264_Q	0.517	0.39
83_D	88_V	0.516	0.39
256_T	260_A	0.516	0.39
220_A	226_L	0.515	0.38
282_A	289_D	0.514	0.38
228_A	239_V	0.513	0.38
233_T	236_T	0.513	0.38
299_Q	315_N	0.513	0.38
30_E	69_T	0.511	0.38
107_Y	111_E	0.511	0.38
166_L	173_V	0.509	0.38
36_L	72_I	0.509	0.38
168_S	171_I	0.508	0.38
176_V	180_S	0.506	0.37
454_V	458_K	0.506	0.37
107_Y	110_E	0.505	0.37
277_K	280_D	0.504	0.37
296_N	305_D	0.503	0.37
344_H	347_L	0.502	0.37
213_S	218_S	0.501	0.37
176_V	179_S	0.500	0.37

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3ly7A	2	0.6152	100	0.591	Contact Map
4ixaA	1	0.1973	99.9	0.75	Contact Map
2jzyA	1	0.2012	99.9	0.752	Contact Map
4nhjA	2	0.1973	99.9	0.753	Contact Map
2hwvA	1	0.1953	99.9	0.754	Contact Map
1opcA	1	0.1914	99.9	0.756	Contact Map
2zxjA	1	0.1934	99.9	0.757	Contact Map
2hqnA	1	0.209	99.9	0.758	Contact Map
2k4jA	1	0.1973	99.9	0.759	Contact Map
3q9vA	1	0.1914	99.9	0.76	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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