CYDC - ECOLI - GREMLIN Contacts

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CYDC - ATP-binding/permease protein CydC

UniProt:	P23886	Sequences: MRALLPYLALYKRHKWMLSLGIVLAIVTLLASIGLLTLSGWFLSASAVAGVAGLYSFNYMLPAAGVRGAAITRTAGRYFERLVSHDATFRVLQHLRIYTFSKLLPLSPAGLARYRQGELLNRVVADVDTLDHLYLRVISPLVGAFVVIMVVTIGLSFLDFTLAFTLGGIMLLTLFLMPPLFYRAGKSTGQNLTHLRGQYRQQLTAWLQGQAELTIFGASDRYRTQLENTEIQWLEAQRRQSELTALSQAIMLLIGALAVILMLWMASGGVGGNAQPGALIALFVFCALAAFEALAPVTGAFQHLGQVIASAVRISDLTDQKPEVTFPDTQTRVADRVSLTLRDVQFTYPEQSQQALKGISLQVNAGEHIAILGRTGCGKSTLLQQLTRAWDPQQGEILLNDSPIASLNEAALRQTISVVPQRVHLFSATLRDNLLLASPGSSDEALSEILRRVGLEKLLEDAGLNSWLGEGGRQLSGGELRRLAIARALLHDAPLVLLDEPTEGLDATTESQILELLAEMMREKTVLMVTHRLRGLSRFQQIIVMDNGQIIEQGTHAELLARQGRYYQFKQGL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10012
Length:	573 (554)
Sequences:	52318 (37195)
Seq/√Len:	1580.2

ECOLI - CYDC MDLA MSBA MDLB CYDD YOJI YDDA ARAG PROV POTG MACB RBSA POTA
BACSU - YGAD YHEH YKNU YHEI YFIC SUNT CYDD YWJA YFIB BMRA YKNV CYDC YVRA OPUAA OPUCA TAGH OPUBA
HALSA - Q9HSQ7 Q9HMX3 Q9HMW0 BTUDA
SULSO - Q97UJ9 Q97VF5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
343_D	358_G	4.543	1.00
367_E	541_Q	4.452	1.00
456_E	464_L	4.412	1.00
340_T	362_Q	4.341	1.00
364_N	367_E	4.284	1.00
342_R	396_E	3.994	1.00
428_A	432_D	3.988	1.00
541_Q	553_Q	3.798	1.00
431_R	443_D	3.746	1.00
556_H	566_Y	3.695	1.00
451_R	456_E	3.652	1.00
396_E	403_P	3.400	1.00
456_E	460_E	3.390	1.00
342_R	398_L	3.371	1.00
338_S	362_Q	3.271	1.00
341_L	344_V	3.205	1.00
357_K	549_Q	3.154	1.00
442_S	445_A	3.024	1.00
563_Q	567_Y	3.003	1.00
431_R	465_N	2.969	1.00
431_R	435_L	2.951	1.00
383_L	529_V	2.906	1.00
345_Q	358_G	2.846	1.00
443_D	447_S	2.790	1.00
450_L	464_L	2.751	1.00
354_Q	357_K	2.719	1.00
383_L	497_L	2.719	1.00
415_T	494_P	2.559	1.00
434_L	450_L	2.501	1.00
340_T	398_L	2.489	1.00
448_E	452_R	2.472	1.00
552_E	562_R	2.455	1.00
363_V	369_I	2.432	1.00
338_S	364_N	2.431	1.00
462_A	466_S	2.411	1.00
388_R	391_D	2.394	1.00
438_S	445_A	2.384	1.00
447_S	456_E	2.380	1.00
417_S	493_A	2.377	1.00
153_I	157_F	2.365	1.00
492_D	524_K	2.332	1.00
552_E	564_G	2.302	1.00
347_T	354_Q	2.291	1.00
543_I	553_Q	2.282	1.00
44_S	277_G	2.281	1.00
361_L	543_I	2.280	1.00
555_T	558_E	2.274	1.00
408_N	411_A	2.260	1.00
447_S	451_R	2.221	1.00
345_Q	354_Q	2.192	1.00
431_R	446_L	2.166	1.00
338_S	365_A	2.161	1.00
44_S	275_Q	2.142	1.00
434_L	446_L	2.139	1.00
368_H	539_F	2.119	1.00
552_E	563_Q	2.113	1.00
341_L	361_L	2.106	1.00
345_Q	394_Q	2.078	1.00
10_L	98_Y	2.074	1.00
337_V	400_N	2.044	1.00
343_D	360_S	2.001	1.00
518_A	538_R	1.989	1.00
455_L	458_L	1.975	1.00
363_V	527_L	1.962	1.00
391_D	405_A	1.950	1.00
315_S	319_D	1.931	1.00
14_H	94_H	1.922	1.00
347_T	393_Q	1.917	1.00
546_D	565_R	1.909	1.00
510_E	532_R	1.901	1.00
447_S	460_E	1.899	1.00
445_A	492_D	1.897	1.00
369_I	541_Q	1.859	1.00
448_E	451_R	1.852	1.00
554_G	558_E	1.843	1.00
12_K	15_K	1.825	1.00
102_K	322_P	1.821	1.00
435_L	446_L	1.802	1.00
449_I	453_V	1.794	1.00
60_M	64_A	1.772	1.00
159_D	269_G	1.769	1.00
195_L	232_Q	1.763	1.00
435_L	443_D	1.757	1.00
511_S	515_E	1.720	1.00
369_I	543_I	1.720	1.00
64_A	68_G	1.700	1.00
382_L	545_M	1.683	1.00
505_L	513_I	1.678	1.00
339_L	527_L	1.661	1.00
450_L	459_L	1.652	1.00
543_I	550_I	1.648	1.00
403_P	406_S	1.647	1.00
336_R	400_N	1.639	1.00
190_Q	312_V	1.630	1.00
457_K	460_E	1.625	1.00
356_L	359_I	1.618	1.00
126_D	313_R	1.617	1.00
552_E	567_Y	1.612	1.00
370_A	539_F	1.611	1.00
371_I	382_L	1.610	1.00
443_D	465_N	1.608	1.00
434_L	490_L	1.601	1.00
218_A	221_R	1.585	1.00
546_D	551_I	1.571	1.00
454_G	512_Q	1.567	1.00
551_I	565_R	1.555	1.00
537_S	557_A	1.550	1.00
452_R	519_E	1.548	1.00
368_H	528_M	1.547	1.00
367_E	540_Q	1.546	1.00
447_S	464_L	1.545	1.00
469_G	474_Q	1.544	1.00
338_S	400_N	1.541	1.00
349_P	352_S	1.513	1.00
371_I	543_I	1.502	1.00
468_L	475_L	1.496	1.00
558_E	562_R	1.486	1.00
444_E	447_S	1.473	1.00
530_T	535_G	1.465	1.00
385_Q	397_I	1.460	1.00
358_G	549_Q	1.455	1.00
156_S	163_A	1.450	1.00
346_F	381_T	1.443	1.00
102_K	106_L	1.441	1.00
450_L	456_E	1.439	1.00
198_Q	232_Q	1.436	1.00
445_A	448_E	1.433	1.00
40_G	281_A	1.431	1.00
364_N	541_Q	1.430	1.00
264_W	268_G	1.415	1.00
105_P	322_P	1.410	1.00
519_E	522_R	1.406	1.00
326_F	408_N	1.399	1.00
335_D	400_N	1.378	1.00
387_T	418_V	1.375	1.00
443_D	446_L	1.373	1.00
438_S	441_S	1.370	1.00
515_E	519_E	1.355	1.00
441_S	490_L	1.349	1.00
374_R	546_D	1.338	1.00
417_S	488_A	1.332	1.00
430_L	483_L	1.329	1.00
202_Q	229_T	1.328	1.00
462_A	467_W	1.327	1.00
61_L	65_G	1.322	1.00
557_A	561_A	1.318	1.00
346_F	385_Q	1.318	1.00
374_R	565_R	1.317	1.00
346_F	390_W	1.313	1.00
445_A	490_L	1.294	1.00
156_S	160_F	1.292	1.00
222_Y	436_L	1.286	1.00
341_L	386_L	1.286	1.00
392_P	404_I	1.285	1.00
184_A	187_S	1.281	1.00
427_S	467_W	1.279	1.00
565_R	568_Q	1.276	1.00
469_G	472_G	1.276	1.00
370_A	536_L	1.275	1.00
344_V	392_P	1.273	1.00
337_V	365_A	1.272	1.00
450_L	455_L	1.269	1.00
461_D	466_S	1.268	1.00
36_L	285_F	1.265	1.00
342_R	360_S	1.262	1.00
102_K	318_T	1.260	1.00
375_T	509_T	1.245	1.00
458_L	479_E	1.244	1.00
24_L	76_G	1.237	1.00
268_G	271_G	1.230	1.00
191_N	236_A	1.222	1.00
435_L	441_S	1.217	1.00
195_L	236_A	1.216	1.00
338_S	401_D	1.215	1.00
369_I	527_L	1.202	1.00
386_L	527_L	1.195	1.00
542_I	556_H	1.194	1.00
449_I	489_L	1.192	1.00
13_R	94_H	1.181	1.00
442_S	490_L	1.176	1.00
521_M	526_V	1.172	1.00
455_L	459_L	1.169	1.00
195_L	198_Q	1.168	1.00
444_E	448_E	1.166	1.00
214_T	219_S	1.165	1.00
224_T	228_N	1.164	1.00
409_E	413_R	1.164	1.00
447_S	450_L	1.164	1.00
33_I	150_V	1.155	1.00
452_R	489_L	1.152	1.00
343_D	394_Q	1.150	1.00
345_Q	357_K	1.149	1.00
365_A	494_P	1.149	1.00
359_I	382_L	1.148	1.00
402_S	406_S	1.146	1.00
209_G	424_H	1.145	1.00
275_Q	278_A	1.144	1.00
112_A	390_W	1.143	1.00
176_L	180_L	1.141	1.00
361_L	382_L	1.135	1.00
220_D	224_T	1.134	1.00
27_V	76_G	1.126	1.00
206_W	222_Y	1.124	1.00
481_R	503_E	1.113	1.00
363_V	525_T	1.112	1.00
402_S	407_L	1.110	1.00
475_L	483_L	1.106	1.00
459_L	464_L	1.103	1.00
97_I	101_S	1.095	1.00
99_T	317_L	1.094	1.00
162_L	282_L	1.094	1.00
336_R	365_A	1.092	1.00
231_I	235_E	1.092	1.00
454_G	509_T	1.081	1.00
40_G	44_S	1.078	1.00
269_G	273_N	1.075	1.00
354_Q	393_Q	1.074	1.00
265_M	269_G	1.072	1.00
530_T	536_L	1.071	1.00
556_H	560_L	1.070	1.00
341_L	397_I	1.070	1.00
462_A	465_N	1.066	1.00
368_H	526_V	1.064	1.00
112_A	384_Q	1.061	1.00
339_L	386_L	1.061	1.00
118_E	197_G	1.057	1.00
397_I	404_I	1.055	1.00
114_Y	118_E	1.052	1.00
460_E	463_G	1.052	1.00
164_F	168_G	1.051	1.00
115_R	118_E	1.050	1.00
19_S	23_V	1.048	1.00
419_V	488_A	1.046	1.00
477_G	482_R	1.043	1.00
102_K	105_P	1.035	1.00
385_Q	392_P	1.027	1.00
160_F	164_F	1.027	1.00
488_A	496_V	1.024	1.00
311_A	315_S	1.023	1.00
101_S	105_P	1.020	1.00
161_T	273_N	1.014	1.00
226_L	230_E	1.014	1.00
339_L	399_L	1.013	1.00
375_T	482_R	1.010	1.00
37_T	41_W	1.010	1.00
222_Y	225_Q	1.009	1.00
198_Q	229_T	1.006	1.00
453_V	486_A	1.004	1.00
348_Y	355_A	1.002	1.00
86_D	90_R	1.000	1.00
545_M	550_I	1.000	1.00
327_P	406_S	1.000	1.00
38_L	62_P	1.000	1.00
340_T	401_D	0.998	1.00
500_E	531_H	0.995	1.00
454_G	516_L	0.994	1.00
367_E	553_Q	0.993	1.00
341_L	382_L	0.992	1.00
155_L	282_L	0.990	1.00
347_T	355_A	0.990	1.00
17_M	86_D	0.988	1.00
432_D	435_L	0.987	1.00
24_L	79_F	0.986	1.00
228_N	232_Q	0.986	1.00
496_V	524_K	0.984	1.00
423_V	484_A	0.982	1.00
399_L	495_L	0.980	1.00
344_V	385_Q	0.979	1.00
454_G	515_E	0.978	1.00
441_S	445_A	0.976	1.00
129_T	310_S	0.975	1.00
544_V	565_R	0.973	1.00
448_E	492_D	0.973	1.00
340_T	360_S	0.972	1.00
411_A	414_Q	0.971	1.00
494_P	524_K	0.971	1.00
213_L	222_Y	0.970	1.00
485_I	498_L	0.964	1.00
460_E	464_L	0.963	1.00
234_L	238_R	0.962	1.00
149_M	153_I	0.962	1.00
380_S	384_Q	0.961	1.00
326_F	409_E	0.961	1.00
468_L	472_G	0.960	1.00
107_S	323_E	0.957	1.00
239_R	242_E	0.956	1.00
468_L	474_Q	0.951	1.00
564_G	567_Y	0.951	1.00
126_D	310_S	0.945	1.00
188_T	239_R	0.945	1.00
169_I	258_A	0.944	1.00
463_G	466_S	0.940	1.00
370_A	530_T	0.937	1.00
399_L	412_L	0.935	1.00
202_Q	225_Q	0.935	1.00
57_F	61_L	0.934	1.00
431_R	464_L	0.932	1.00
218_A	222_Y	0.932	1.00
122_R	316_D	0.931	1.00
94_H	98_Y	0.928	1.00
165_T	265_M	0.928	1.00
225_Q	229_T	0.927	1.00
354_Q	394_Q	0.926	1.00
68_G	72_T	0.926	1.00
358_G	394_Q	0.924	1.00
469_G	473_R	0.924	1.00
454_G	519_E	0.922	1.00
98_Y	102_K	0.922	1.00
434_L	483_L	0.920	1.00
407_L	412_L	0.920	1.00
24_L	83_V	0.919	1.00
528_M	539_F	0.918	1.00
431_R	447_S	0.918	1.00
21_G	84_S	0.917	1.00
270_V	274_A	0.916	1.00
377_C	545_M	0.913	1.00
512_Q	515_E	0.910	1.00
40_G	278_A	0.906	1.00
347_T	350_E	0.903	1.00
324_V	391_D	0.899	1.00
532_R	535_G	0.898	1.00
392_P	405_A	0.898	1.00
158_L	278_A	0.897	1.00
419_V	485_I	0.896	1.00
190_Q	194_H	0.896	1.00
387_T	497_L	0.894	1.00
266_A	279_L	0.894	1.00
221_R	225_Q	0.891	1.00
449_I	490_L	0.890	1.00
9_A	12_K	0.887	1.00
451_R	460_E	0.887	1.00
231_I	234_L	0.886	1.00
191_N	195_L	0.885	1.00
359_I	550_I	0.883	1.00
15_K	19_S	0.883	1.00
227_E	231_I	0.881	1.00
508_T	512_Q	0.880	1.00
392_P	397_I	0.879	1.00
446_L	464_L	0.879	1.00
41_W	45_A	0.879	1.00
175_F	179_P	0.878	1.00
452_R	520_M	0.878	1.00
334_A	400_N	0.873	1.00
180_L	184_A	0.873	1.00
110_G	114_Y	0.871	1.00
184_A	243_L	0.871	1.00
308_I	312_V	0.868	1.00
93_Q	97_I	0.868	1.00
191_N	239_R	0.866	1.00
188_T	236_A	0.866	1.00
396_E	405_A	0.865	1.00
232_Q	236_A	0.865	1.00
411_A	415_T	0.865	1.00
370_A	542_I	0.865	1.00
388_R	409_E	0.863	1.00
61_L	64_A	0.863	1.00
450_L	453_V	0.862	1.00
558_E	561_A	0.862	1.00
502_T	513_I	0.860	1.00
446_L	490_L	0.856	1.00
99_T	123_V	0.856	1.00
550_I	553_Q	0.853	1.00
368_H	521_M	0.853	1.00
425_L	483_L	0.851	1.00
152_T	163_A	0.847	1.00
387_T	416_I	0.847	1.00
155_L	163_A	0.841	1.00
31_A	72_T	0.840	1.00
339_L	495_L	0.840	1.00
332_R	407_L	0.835	1.00
16_W	20_L	0.834	1.00
99_T	314_I	0.834	1.00
404_I	412_L	0.833	1.00
109_A	323_E	0.832	1.00
368_H	518_A	0.831	1.00
184_A	188_T	0.830	1.00
345_Q	393_Q	0.830	1.00
365_A	400_N	0.829	1.00
14_H	90_R	0.829	1.00
221_R	224_T	0.827	1.00
425_L	480_L	0.826	1.00
212_E	216_F	0.824	1.00
177_M	250_I	0.824	1.00
347_T	352_S	0.824	1.00
514_L	530_T	0.824	1.00
349_P	353_Q	0.819	1.00
75_A	79_F	0.816	1.00
31_A	76_G	0.816	1.00
410_A	414_Q	0.815	1.00
493_A	524_K	0.814	1.00
453_V	482_R	0.812	1.00
496_V	521_M	0.811	1.00
435_L	440_G	0.810	1.00
321_K	325_T	0.809	1.00
192_L	237_Q	0.808	1.00
429_T	432_D	0.807	1.00
224_T	227_E	0.807	1.00
225_Q	228_N	0.807	1.00
187_S	191_N	0.806	1.00
546_D	549_Q	0.804	1.00
106_L	320_Q	0.804	1.00
211_A	384_Q	0.802	1.00
277_G	281_A	0.802	1.00
332_R	335_D	0.802	1.00
27_V	72_T	0.800	1.00
102_K	321_K	0.799	1.00
496_V	526_V	0.797	1.00
407_L	411_A	0.794	1.00
21_G	87_A	0.794	1.00
210_Q	214_T	0.788	1.00
223_R	227_E	0.786	1.00
332_R	411_A	0.779	1.00
337_V	525_T	0.779	1.00
342_R	362_Q	0.779	1.00
220_D	223_R	0.777	1.00
119_L	317_L	0.777	1.00
447_S	459_L	0.777	1.00
31_A	69_A	0.777	1.00
154_G	158_L	0.775	1.00
434_L	464_L	0.774	1.00
270_V	279_L	0.772	1.00
37_T	154_G	0.770	1.00
372_L	544_V	0.770	1.00
392_P	396_E	0.770	1.00
118_E	122_R	0.768	1.00
161_T	164_F	0.768	1.00
229_T	232_Q	0.768	1.00
159_D	163_A	0.766	1.00
398_L	401_D	0.765	1.00
38_L	69_A	0.764	1.00
510_E	514_L	0.764	1.00
30_L	34_G	0.761	1.00
103_L	111_L	0.761	1.00
63_A	67_R	0.761	1.00
414_Q	491_H	0.759	1.00
435_L	438_S	0.759	1.00
328_D	332_R	0.757	1.00
416_I	495_L	0.757	1.00
41_W	62_P	0.754	1.00
23_V	27_V	0.754	1.00
455_L	483_L	0.752	1.00
435_L	439_P	0.751	1.00
330_Q	402_S	0.751	1.00
209_G	212_E	0.751	1.00
157_F	160_F	0.751	1.00
109_A	113_R	0.750	1.00
331_T	411_A	0.750	1.00
314_I	318_T	0.748	1.00
330_Q	406_S	0.747	1.00
8_L	11_Y	0.746	1.00
133_L	307_V	0.745	1.00
107_S	324_V	0.745	1.00
72_T	76_G	0.744	1.00
64_A	67_R	0.744	1.00
347_T	353_Q	0.741	1.00
357_K	547_N	0.741	1.00
514_L	535_G	0.740	1.00
557_A	560_L	0.740	1.00
236_A	239_R	0.739	1.00
375_T	500_E	0.739	1.00
44_S	47_A	0.739	1.00
560_L	567_Y	0.739	1.00
481_R	504_G	0.735	1.00
41_W	44_S	0.735	1.00
238_R	242_E	0.735	1.00
17_M	83_V	0.733	1.00
443_D	464_L	0.732	1.00
38_L	65_G	0.730	1.00
37_T	40_G	0.730	1.00
195_L	229_T	0.729	1.00
477_G	504_G	0.729	1.00
161_T	269_G	0.729	1.00
266_A	270_V	0.729	1.00
29_L	146_V	0.728	1.00
154_G	157_F	0.728	1.00
426_F	433_N	0.726	1.00
12_K	16_W	0.726	1.00
25_A	143_G	0.724	1.00
162_L	269_G	0.723	1.00
183_R	187_S	0.723	1.00
78_Y	82_L	0.722	1.00
129_T	306_Q	0.718	1.00
144_A	296_P	0.718	1.00
133_L	304_L	0.717	1.00
422_R	480_L	0.717	1.00
65_G	68_G	0.716	1.00
199_Y	233_W	0.716	1.00
176_L	179_P	0.714	1.00
71_I	75_A	0.713	1.00
179_P	183_R	0.713	1.00
366_G	525_T	0.712	1.00
334_A	494_P	0.712	1.00
452_R	456_E	0.711	1.00
8_L	12_K	0.709	1.00
156_S	167_G	0.708	1.00
232_Q	235_E	0.708	1.00
366_G	523_E	0.707	1.00
253_L	257_L	0.707	1.00
145_F	149_M	0.705	1.00
168_G	171_L	0.704	1.00
329_T	411_A	0.704	1.00
513_I	516_L	0.701	1.00
235_E	239_R	0.701	1.00
443_D	450_L	0.701	1.00
45_A	48_V	0.700	1.00
122_R	126_D	0.699	1.00
20_L	83_V	0.697	1.00
159_D	274_A	0.696	1.00
353_Q	357_K	0.696	1.00
399_L	404_I	0.695	1.00
369_I	553_Q	0.694	1.00
58_N	61_L	0.694	1.00
150_V	153_I	0.694	1.00
445_A	449_I	0.692	1.00
17_M	90_R	0.692	1.00
45_A	58_N	0.692	1.00
502_T	510_E	0.691	1.00
329_T	408_N	0.690	1.00
98_Y	101_S	0.690	1.00
398_L	403_P	0.688	1.00
193_T	196_R	0.687	1.00
425_L	468_L	0.687	1.00
363_V	367_E	0.687	1.00
158_L	281_A	0.686	1.00
356_L	545_M	0.685	1.00
141_L	145_F	0.685	1.00
151_V	289_A	0.685	1.00
562_R	565_R	0.684	1.00
331_T	408_N	0.679	1.00
106_L	322_P	0.679	1.00
341_L	359_I	0.679	1.00
99_T	318_T	0.679	1.00
482_R	509_T	0.678	1.00
33_I	36_L	0.677	1.00
62_P	65_G	0.677	1.00
455_L	464_L	0.675	1.00
438_S	492_D	0.674	1.00
279_L	282_L	0.673	1.00
95_L	127_V	0.672	1.00
536_L	539_F	0.671	1.00
101_S	223_R	0.670	1.00
282_L	286_C	0.668	1.00
151_V	290_A	0.668	1.00
454_G	457_K	0.666	1.00
541_Q	555_T	0.666	1.00
428_A	467_W	0.666	1.00
191_N	194_H	0.665	1.00
412_L	416_I	0.665	1.00
438_S	491_H	0.665	1.00
383_L	527_L	0.664	1.00
346_F	355_A	0.664	1.00
160_F	163_A	0.663	1.00
385_Q	390_W	0.661	1.00
485_I	489_L	0.658	1.00
281_A	284_V	0.657	1.00
265_M	268_G	0.656	1.00
44_S	48_V	0.656	1.00
92_L	131_D	0.655	1.00
37_T	158_L	0.653	1.00
384_Q	390_W	0.653	1.00
130_L	311_A	0.653	1.00
115_R	201_Q	0.650	1.00
497_L	527_L	0.650	1.00
552_E	559_L	0.650	1.00
312_V	316_D	0.647	1.00
510_E	535_G	0.646	1.00
336_R	525_T	0.645	1.00
340_T	396_E	0.645	1.00
556_H	559_L	0.645	1.00
435_L	450_L	0.645	1.00
324_V	388_R	0.644	1.00
482_R	505_L	0.644	1.00
102_K	320_Q	0.641	1.00
153_I	156_S	0.639	1.00
307_V	310_S	0.639	1.00
427_S	469_G	0.639	1.00
553_Q	558_E	0.639	1.00
371_I	527_L	0.638	1.00
269_G	272_G	0.637	1.00
197_G	313_R	0.636	1.00
454_G	513_I	0.636	1.00
438_S	442_S	0.636	1.00
348_Y	381_T	0.635	1.00
446_L	449_I	0.634	1.00
446_L	450_L	0.634	1.00
252_L	295_A	0.633	1.00
121_N	200_R	0.633	1.00
130_L	314_I	0.633	1.00
552_E	565_R	0.632	1.00
28_T	77_R	0.630	1.00
361_L	550_I	0.630	1.00
452_R	516_L	0.630	1.00
456_E	459_L	0.629	1.00
552_E	560_L	0.627	1.00
427_S	474_Q	0.627	1.00
98_Y	318_T	0.627	1.00
118_E	313_R	0.626	1.00
126_D	193_T	0.626	1.00
43_L	280_I	0.626	1.00
485_I	513_I	0.625	1.00
85_H	136_R	0.624	1.00
347_T	394_Q	0.623	1.00
430_L	459_L	0.623	1.00
99_T	127_V	0.623	1.00
400_N	494_P	0.622	1.00
108_P	112_A	0.622	1.00
422_R	471_G	0.621	1.00
337_V	494_P	0.621	1.00
241_S	245_A	0.620	1.00
58_N	62_P	0.620	1.00
92_L	96_R	0.619	1.00
429_T	465_N	0.618	1.00
329_T	332_R	0.618	1.00
14_H	91_V	0.617	1.00
507_A	510_E	0.616	1.00
541_Q	558_E	0.616	1.00
552_E	568_Q	0.614	1.00
344_V	360_S	0.613	1.00
359_I	545_M	0.611	1.00
90_R	93_Q	0.611	1.00
547_N	551_I	0.610	1.00
383_L	418_V	0.610	1.00
472_G	480_L	0.609	1.00
14_H	17_M	0.609	1.00
510_E	534_R	0.609	1.00
27_V	31_A	0.609	1.00
281_A	285_F	0.609	1.00
363_V	368_H	0.608	1.00
113_R	349_P	0.608	1.00
177_M	254_I	0.608	1.00
453_V	485_I	0.607	1.00
505_L	509_T	0.607	1.00
350_E	393_Q	0.606	1.00
25_A	80_E	0.606	1.00
375_T	530_T	0.606	1.00
267_S	270_V	0.605	1.00
335_D	415_T	0.605	1.00
163_A	282_L	0.604	1.00
95_L	130_L	0.604	1.00
40_G	277_G	0.602	1.00
350_E	353_Q	0.601	1.00
60_M	63_A	0.600	1.00
364_N	369_I	0.599	1.00
132_H	303_H	0.598	1.00
368_H	538_R	0.598	1.00
93_Q	230_E	0.595	1.00
274_A	279_L	0.594	1.00
544_V	552_E	0.594	1.00
100_F	104_L	0.593	1.00
181_F	247_S	0.593	1.00
344_V	395_G	0.593	1.00
159_D	162_L	0.592	1.00
189_G	240_Q	0.592	1.00
353_Q	547_N	0.591	1.00
419_V	498_L	0.591	1.00
13_R	16_W	0.591	1.00
9_A	98_Y	0.591	1.00
476_S	479_E	0.591	1.00
409_E	412_L	0.591	1.00
212_E	215_I	0.590	1.00
466_S	469_G	0.590	1.00
292_E	296_P	0.590	1.00
110_G	119_L	0.590	1.00
359_I	543_I	0.589	1.00
121_N	196_R	0.588	1.00
143_G	147_V	0.587	1.00
417_S	491_H	0.587	1.00
19_S	22_I	0.586	1.00
195_L	233_W	0.586	1.00
542_I	555_T	0.586	1.00
193_T	309_A	0.585	1.00
191_N	232_Q	0.585	1.00
399_L	407_L	0.583	1.00
495_L	525_T	0.580	1.00
257_L	261_L	0.579	1.00
350_E	354_Q	0.579	1.00
514_L	528_M	0.577	1.00
34_G	69_A	0.577	1.00
354_Q	358_G	0.577	1.00
458_L	464_L	0.576	1.00
128_D	131_D	0.576	1.00
402_S	411_A	0.576	1.00
76_G	79_F	0.575	1.00
132_H	136_R	0.575	1.00
375_T	505_L	0.574	1.00
327_P	330_Q	0.573	1.00
344_V	397_I	0.573	1.00
448_E	520_M	0.573	1.00
562_R	567_Y	0.573	1.00
144_A	148_I	0.573	1.00
107_S	110_G	0.572	1.00
16_W	19_S	0.572	1.00
239_R	243_L	0.572	1.00
478_G	506_D	0.572	1.00
451_R	464_L	0.572	1.00
121_N	197_G	0.571	1.00
274_A	278_A	0.571	1.00
438_S	490_L	0.571	1.00
88_T	135_L	0.570	1.00
433_N	483_L	0.569	1.00
194_H	198_Q	0.569	1.00
392_P	403_P	0.568	1.00
495_L	527_L	0.568	1.00
453_V	489_L	0.567	1.00
357_K	360_S	0.567	1.00
140_P	296_P	0.566	1.00
188_T	191_N	0.566	1.00
121_N	125_A	0.565	1.00
435_L	490_L	0.565	1.00
563_Q	568_Q	0.565	1.00
537_S	556_H	0.565	1.00
310_S	313_R	0.564	1.00
328_D	406_S	0.563	1.00
108_P	389_A	0.561	1.00
261_L	265_M	0.561	1.00
515_E	518_A	0.561	1.00
235_E	238_R	0.561	1.00
384_Q	418_V	0.560	1.00
459_L	462_A	0.560	1.00
202_Q	206_W	0.559	1.00
28_T	76_G	0.558	1.00
278_A	281_A	0.558	1.00
516_L	520_M	0.558	1.00
451_R	457_K	0.557	1.00
47_A	50_G	0.557	1.00
335_D	399_L	0.556	1.00
515_E	538_R	0.555	1.00
530_T	534_R	0.554	1.00
335_D	365_A	0.554	1.00
256_A	260_I	0.553	1.00
89_F	92_L	0.553	1.00
419_V	501_P	0.552	1.00
245_A	249_A	0.551	1.00
330_Q	333_V	0.551	1.00
166_L	286_C	0.551	1.00
371_I	545_M	0.550	1.00
501_P	530_T	0.549	1.00
328_D	408_N	0.549	1.00
544_V	551_I	0.549	1.00
509_T	513_I	0.547	1.00
65_G	69_A	0.547	1.00
489_L	520_M	0.547	1.00
74_T	78_Y	0.545	1.00
148_I	152_T	0.545	1.00
127_V	314_I	0.544	1.00
339_L	363_V	0.544	1.00
368_H	523_E	0.543	1.00
372_L	536_L	0.543	1.00
161_T	265_M	0.542	1.00
430_L	455_L	0.542	1.00
434_L	437_A	0.542	1.00
560_L	563_Q	0.541	1.00
516_L	519_E	0.541	1.00
430_L	468_L	0.541	1.00
85_H	89_F	0.541	1.00
334_A	337_V	0.540	1.00
48_V	51_V	0.539	1.00
104_L	107_S	0.538	1.00
152_T	156_S	0.537	1.00
364_N	525_T	0.537	1.00
167_G	171_L	0.535	1.00
14_H	87_A	0.535	1.00
116_Q	120_L	0.534	1.00
506_D	509_T	0.533	1.00
11_Y	18_L	0.533	1.00
122_R	313_R	0.533	1.00
546_D	568_Q	0.533	1.00
79_F	83_V	0.533	1.00
151_V	285_F	0.532	1.00
35_L	39_S	0.531	1.00
13_R	98_Y	0.531	1.00
57_F	60_M	0.531	1.00
202_Q	222_Y	0.531	1.00
111_L	114_Y	0.530	1.00
535_G	539_F	0.529	1.00
209_G	426_F	0.529	1.00
38_L	41_W	0.528	1.00
196_R	200_R	0.528	1.00
363_V	543_I	0.528	1.00
117_G	201_Q	0.527	1.00
10_L	95_L	0.527	1.00
109_A	349_P	0.526	1.00
381_T	385_Q	0.526	1.00
520_M	523_E	0.526	1.00
528_M	536_L	0.526	1.00
450_L	458_L	0.526	1.00
123_V	127_V	0.525	1.00
32_S	73_R	0.525	1.00
327_P	408_N	0.525	1.00
266_A	269_G	0.525	1.00
489_L	516_L	0.524	1.00
341_L	385_Q	0.523	1.00
39_S	43_L	0.522	1.00
46_S	58_N	0.522	1.00
521_M	524_K	0.522	1.00
82_L	86_D	0.521	1.00
527_L	543_I	0.521	1.00
37_T	281_A	0.521	1.00
67_R	71_I	0.520	1.00
197_G	309_A	0.519	1.00
22_I	25_A	0.518	1.00
420_P	423_V	0.517	1.00
482_R	504_G	0.517	1.00
144_A	147_V	0.517	1.00
188_T	240_Q	0.516	1.00
380_S	383_L	0.516	1.00
388_R	404_I	0.515	1.00
372_L	533_L	0.515	1.00
355_A	359_I	0.514	1.00
551_I	563_Q	0.514	1.00
233_W	237_Q	0.514	1.00
42_F	62_P	0.514	1.00
17_M	87_A	0.513	1.00
444_E	451_R	0.512	1.00
381_T	390_W	0.512	1.00
283_F	286_C	0.511	1.00
514_L	538_R	0.510	1.00
345_Q	360_S	0.510	1.00
192_L	240_Q	0.510	1.00
183_R	186_K	0.508	1.00
213_L	219_S	0.508	1.00
403_P	407_L	0.508	1.00
199_Y	203_L	0.507	1.00
125_A	193_T	0.507	1.00
171_L	176_L	0.504	1.00
38_L	66_V	0.504	1.00
507_A	534_R	0.503	1.00
485_I	505_L	0.502	1.00
331_T	402_S	0.502	1.00
408_N	412_L	0.501	1.00
114_Y	119_L	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4ry2A	2	0.9668	100	0.084	Contact Map
4a82A	2	0.993	100	0.115	Contact Map
4q4hB	1	0.9878	100	0.144	Contact Map
3b5xA	2	0.9878	100	0.148	Contact Map
3b60A	2	0.9878	100	0.149	Contact Map
4f4cA	1	0.9756	100	0.153	Contact Map
4q4hA	1	0.9878	100	0.159	Contact Map
3zdqA	2	0.9756	100	0.161	Contact Map
4mrsA	2	0.9948	100	0.167	Contact Map
4q9hA	1	0.9965	100	0.171	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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