GREMLIN Database
PRC - Tail-specific protease
UniProt: P23865 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10760
Length: 682 (639)
Sequences: 826 (559)
Seq/√Len: 22.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
446_V474_T10.4981.00
461_M467_A9.6231.00
385_V388_V7.9281.00
87_A91_E7.4901.00
394_S447_D6.6781.00
64_Q101_G5.9871.00
377_L388_V5.1701.00
273_S333_L4.4251.00
72_D97_K4.3491.00
68_A97_K4.2621.00
143_N611_V3.9851.00
64_Q102_D3.9461.00
376_Q379_K3.9271.00
286_G292_M3.8751.00
284_G292_M3.8361.00
412_P435_Q3.8241.00
92_Q118_L3.8111.00
390_I457_F3.7361.00
82_H154_P3.5871.00
407_S416_I3.5321.00
94_A97_K3.5151.00
362_I390_I3.4331.00
164_A167_D3.3741.00
276_I319_I3.3351.00
144_D168_S3.1641.00
459_A517_G3.1551.00
443_V470_V3.1081.00
443_V663_A3.0471.00
122_R125_E3.0391.00
156_P162_L3.0011.00
293_V306_L2.9980.99
357_V387_S2.9730.99
512_Y551_D2.8560.99
236_Q308_K2.8390.99
239_T308_K2.8150.99
377_L385_V2.7680.99
314_K334_T2.7480.99
314_K332_T2.7340.99
355_E386_S2.6120.99
86_L122_R2.5540.98
412_P436_V2.5220.98
470_V659_T2.4940.98
347_M376_Q2.4580.98
68_A94_A2.4340.98
86_L162_L2.4340.98
624_L628_N2.3900.97
510_K551_D2.3860.97
140_F175_L2.3570.97
158_N161_E2.3560.97
164_A168_S2.3500.97
273_S319_I2.3270.97
333_L338_I2.3240.97
178_K609_Y2.2440.96
459_A515_N2.2310.96
239_T245_L2.2220.96
259_T303_V2.1890.96
407_S461_M2.1860.96
157_K161_E2.1720.95
347_M379_K2.1600.95
316_R330_T2.1580.95
144_D167_D2.1560.95
449_F539_T2.1480.95
144_D171_K2.1430.95
351_T356_K2.1090.95
68_A72_D2.1050.95
130_A170_V2.0880.94
64_Q67_S2.0730.94
87_A94_A2.0530.94
174_E187_I2.0460.94
614_K618_E2.0250.93
369_L438_Y2.0130.93
74_Y115_L1.9910.93
380_L388_V1.9860.93
68_A98_T1.9820.93
91_E94_A1.9820.93
184_D188_R1.9790.92
121_K125_E1.9720.92
211_F215_M1.9640.92
183_T186_E1.9590.92
511_F519_T1.9580.92
273_S331_V1.9470.92
160_A163_N1.9050.91
273_S276_I1.8920.91
579_I585_F1.8490.90
617_N621_A1.8100.89
388_V442_L1.8070.89
433_D436_V1.7960.88
261_I273_S1.7800.88
362_I369_L1.7610.87
311_K336_E1.7560.87
145_T604_I1.7500.87
232_R305_A1.7320.86
85_L90_V1.7320.86
159_E163_N1.7170.86
377_L381_E1.7070.85
404_V416_I1.6990.85
62_L70_I1.6950.85
609_Y613_E1.6920.85
38_E41_H1.6780.84
266_A403_A1.6570.84
132_S163_N1.6540.84
275_A329_R1.6440.83
374_K437_F1.6400.83
426_V554_D1.6300.83
170_V173_D1.6210.82
167_D171_K1.6190.82
373_V406_L1.6170.82
345_V373_V1.6130.82
129_Y133_V1.6090.82
63_D546_N1.6070.82
368_G371_D1.5970.81
281_K320_L1.5900.81
368_G467_A1.5740.80
89_D122_R1.5730.80
139_D142_G1.5640.80
381_E440_G1.5450.79
411_I431_D1.5350.79
292_M318_E1.5270.78
591_D626_R1.5270.78
374_K435_Q1.5240.78
286_G289_G1.5210.78
150_R165_L1.5160.78
624_L627_L1.5000.77
243_L344_A1.4990.77
251_V263_S1.4960.77
87_A154_P1.4940.77
209_D299_R1.4890.76
85_L115_L1.4870.76
135_E192_T1.4870.76
211_F297_G1.4830.76
275_A319_I1.4680.75
143_N608_N1.4650.75
347_M383_Q1.4650.75
93_F118_L1.4540.75
110_D283_V1.4520.75
238_N503_S1.4500.74
113_Y210_V1.4480.74
245_L258_Y1.4450.74
606_S611_V1.4340.74
387_S663_A1.4300.73
67_S101_G1.4250.73
389_I443_V1.4190.73
309_G335_R1.4080.72
19_Q23_V1.3870.71
357_V663_A1.3870.71
126_R163_N1.3720.70
658_E662_I1.3680.70
30_D33_P1.3630.70
76_N82_H1.3570.69
412_P433_D1.3490.69
251_V265_V1.3480.69
184_D187_I1.3450.69
518_S550_W1.3440.69
124_F199_I1.3270.68
250_A480_V1.3050.66
26_I30_D1.2900.65
230_S303_V1.2790.65
349_V385_V1.2740.64
99_E158_N1.2680.64
375_V378_Q1.2560.63
368_G461_M1.2530.63
247_G335_R1.2410.62
459_A514_V1.2340.62
26_I29_A1.2330.62
74_Y84_V1.2280.61
528_I662_I1.2190.61
75_L90_V1.2190.61
411_I433_D1.2170.61
247_G309_G1.2160.61
336_E433_D1.2130.60
389_I625_A1.2110.60
269_P297_G1.2090.60
142_G171_K1.2080.60
186_E189_E1.2060.60
367_V399_A1.2020.60
137_P184_D1.2000.60
226_T253_Q1.1990.59
468_L666_L1.1970.59
261_I331_V1.1940.59
370_T405_S1.1890.59
292_M330_T1.1880.59
356_K383_Q1.1870.59
403_A409_L1.1860.59
360_L442_L1.1750.58
350_K660_V1.1700.58
236_Q239_T1.1680.57
408_G431_D1.1680.57
401_T405_S1.1660.57
457_F467_A1.1620.57
237_F396_G1.1570.57
27_T31_Q1.1560.57
385_V442_L1.1540.57
658_E665_D1.1520.56
157_K189_E1.1510.56
125_E159_E1.1490.56
606_S615_E1.1450.56
417_V478_G1.1450.56
375_V379_K1.1410.56
594_R622_T1.1350.55
129_Y163_N1.1290.55
174_E184_D1.1290.55
468_L662_I1.1280.55
431_D436_V1.1270.55
64_Q98_T1.1250.55
302_D558_Y1.1250.55
585_F589_M1.1240.54
345_V360_L1.1230.54
70_I470_V1.1200.54
379_K383_Q1.1190.54
381_E439_K1.1190.54
103_E108_K1.1160.54
111_V115_L1.1160.54
630_R634_E1.1080.53
586_Q589_M1.1060.53
21_F25_D1.1060.53
245_L264_M1.1030.53
362_I438_Y1.1020.53
624_L631_F1.1000.53
246_E311_K1.0980.53
595_F599_K1.0950.53
347_M380_L1.0920.52
231_P246_E1.0880.52
572_L576_N1.0880.52
573_K577_A1.0870.52
662_I665_D1.0830.52
71_F97_K1.0790.51
377_L380_L1.0760.51
629_E632_K1.0710.51
404_V430_S1.0660.51
247_G478_G1.0650.50
27_T30_D1.0560.50
521_R547_A1.0510.50
86_L140_F1.0490.49
103_E111_V1.0490.49
115_L119_A1.0490.49
177_L180_T1.0480.49
412_P431_D1.0470.49
404_V429_D1.0460.49
247_G417_V1.0400.49
88_S122_R1.0390.49
483_Y505_Q1.0300.48
145_T160_A1.0280.48
230_S339_R1.0260.48
473_P525_T1.0210.47
331_V641_K1.0200.47
178_K181_G1.0190.47
522_K525_T1.0170.47
575_H578_R1.0160.47
618_E622_T1.0160.47
248_I478_G1.0150.47
110_D597_A1.0140.47
399_A403_A1.0130.47
91_E99_E1.0130.47
622_T625_A1.0110.47
358_G380_L1.0100.47
370_T406_L1.0100.47
283_V328_T1.0100.47
169_K173_D1.0090.47
52_F505_Q1.0090.47
270_A273_S1.0080.47
610_A613_E1.0070.47
371_D467_A1.0060.46
73_R221_E1.0050.46
576_N580_A1.0030.46
192_T196_K1.0020.46
286_G316_R1.0010.46
248_I335_R1.0000.46
160_A576_N0.9990.46
469_V611_V0.9950.46
85_L468_L0.9940.46
411_I436_V0.9930.46
85_L119_A0.9920.46
357_V386_S0.9870.45
150_R153_A0.9850.45
457_F461_M0.9850.45
377_L439_K0.9840.45
640_K644_D0.9830.45
461_M588_I0.9830.45
258_Y333_L0.9820.45
140_F171_K0.9810.45
157_K474_T0.9810.45
73_R546_N0.9780.45
155_W194_R0.9770.45
608_N611_V0.9710.44
141_T610_A0.9680.44
291_P338_I0.9680.44
146_Y223_D0.9670.44
44_V208_E0.9660.44
331_V361_D0.9650.44
621_A659_T0.9640.44
74_Y159_E0.9630.44
73_R222_I0.9620.43
247_G456_I0.9600.43
125_E132_S0.9590.43
245_L340_L0.9590.43
405_S420_R0.9570.43
308_K368_G0.9540.43
193_R299_R0.9520.43
407_S444_V0.9470.42
613_E617_N0.9470.42
624_L630_R0.9470.42
145_T168_S0.9460.42
417_V456_I0.9420.42
182_K186_E0.9390.42
411_I414_G0.9370.42
21_F27_T0.9310.41
264_M270_A0.9280.41
586_Q590_K0.9240.41
469_V580_A0.9230.41
370_T663_A0.9220.41
86_L156_P0.9220.41
577_A580_A0.9160.40
98_T101_G0.9150.40
143_N382_K0.9120.40
237_F250_A0.9110.40
178_K187_I0.9100.40
246_E299_R0.9090.40
637_P640_K0.9090.40
90_V352_V0.9080.40
65_A271_A0.9060.40
632_K636_K0.9050.40
381_E438_Y0.9040.40
74_Y331_V0.9040.40
107_G518_S0.9030.40
286_G290_K0.9020.40
276_I399_A0.9010.39
443_V474_T0.9000.39
232_R545_D0.8980.39
265_V333_L0.8980.39
308_K456_I0.8980.39
248_I309_G0.8940.39
629_E634_E0.8940.39
345_V480_V0.8940.39
457_F547_A0.8920.39
74_Y595_F0.8890.39
221_E509_Q0.8880.39
201_R265_V0.8880.39
335_R417_V0.8870.39
219_A229_L0.8860.38
135_E196_K0.8850.38
253_Q338_I0.8840.38
628_N636_K0.8830.38
575_H658_E0.8830.38
88_S296_I0.8810.38
444_V467_A0.8810.38
357_V528_I0.8790.38
237_F252_L0.8790.38
131_L192_T0.8780.38
345_V376_Q0.8770.38
630_R636_K0.8760.38
187_I612_R0.8730.38
335_R478_G0.8720.38
252_L480_V0.8720.38
641_K644_D0.8710.38
295_V306_L0.8710.38
403_A437_F0.8690.37
658_E663_A0.8640.37
414_G431_D0.8630.37
333_L336_E0.8620.37
590_K622_T0.8610.37
25_D30_D0.8600.37
348_S590_K0.8570.37
261_I522_K0.8560.37
570_E574_E0.8540.36
308_K335_R0.8530.36
183_T187_I0.8530.36
568_E572_L0.8520.36
87_A157_K0.8510.36
628_N635_G0.8440.36
456_I478_G0.8430.36
19_Q25_D0.8430.36
112_F214_A0.8390.35
148_L223_D0.8380.35
530_M579_I0.8360.35
248_I417_V0.8350.35
578_R658_E0.8340.35
239_T504_V0.8320.35
260_V508_I0.8320.35
335_R456_I0.8310.35
23_V26_I0.8300.35
312_G419_V0.8280.35
211_F269_P0.8270.35
153_A165_L0.8260.35
611_V614_K0.8260.35
265_V407_S0.8250.35
239_T368_G0.8240.35
20_T23_V0.8230.35
321_P329_R0.8220.34
611_V615_E0.8200.34
237_F241_M0.8180.34
251_V458_A0.8180.34
400_L456_I0.8180.34
315_V335_R0.8170.34
128_Q199_I0.8160.34
54_R556_A0.8110.34
67_S97_K0.8110.34
71_F548_L0.8090.34
515_N558_Y0.8090.34
231_P297_G0.8080.34
347_M662_I0.8080.34
100_L214_A0.8030.33
82_H284_G0.8020.33
200_R542_K0.8020.33
103_E535_E0.8000.33
558_Y561_S0.8000.33
157_K160_A0.7990.33
143_N621_A0.7980.33
74_Y632_K0.7980.33
175_L609_Y0.7860.32
316_R332_T0.7860.32
641_K645_L0.7850.32
100_L603_N0.7820.32
243_L612_R0.7810.32
309_G417_V0.7810.32
216_T341_E0.7810.32
170_V446_V0.7800.32
444_V461_M0.7800.32
276_I331_V0.7790.32
71_F208_E0.7790.32
21_F31_Q0.7730.31
582_D661_N0.7710.31
82_H152_K0.7710.31
459_A524_V0.7700.31
396_G454_S0.7690.31
456_I519_T0.7690.31
82_H165_L0.7670.31
405_S485_S0.7670.31
315_V456_I0.7660.31
179_L612_R0.7660.31
306_L329_R0.7660.31
265_V275_A0.7650.31
189_E193_R0.7650.31
451_A455_E0.7650.31
172_F467_A0.7640.31
35_L226_T0.7640.31
583_P586_Q0.7630.31
250_A307_I0.7630.31
253_Q262_N0.7600.31
521_R525_T0.7580.31
444_V473_P0.7580.31
75_L424_G0.7580.31
23_V31_Q0.7570.31
248_I285_V0.7550.30
443_V582_D0.7530.30
465_G563_D0.7530.30
357_V375_V0.7530.30
255_D438_Y0.7520.30
465_G585_F0.7520.30
248_I519_T0.7510.30
349_V356_K0.7500.30
63_D219_A0.7500.30
48_V275_A0.7500.30
254_M300_L0.7490.30
438_Y442_L0.7490.30
248_I308_K0.7480.30
140_F143_N0.7460.30
574_E577_A0.7450.30
296_I340_L0.7450.30
286_G330_T0.7440.30
204_Q299_R0.7440.30
610_A614_K0.7440.30
467_A588_I0.7430.30
462_Q527_D0.7420.30
388_V597_A0.7390.30
190_T257_D0.7380.29
86_L91_E0.7380.29
247_G315_V0.7350.29
302_D616_N0.7350.29
577_A581_K0.7340.29
574_E668_K0.7340.29
315_V417_V0.7320.29
142_G167_D0.7320.29
638_E642_L0.7310.29
20_T29_A0.7290.29
318_E330_T0.7290.29
148_L447_D0.7280.29
269_P359_V0.7270.29
29_A32_I0.7270.29
255_D389_I0.7260.29
109_L615_E0.7250.29
459_A626_R0.7250.29
102_D158_N0.7210.29
428_E431_D0.7200.28
250_A335_R0.7200.28
87_A98_T0.7200.28
345_V407_S0.7200.28
94_A98_T0.7190.28
380_L446_V0.7180.28
630_R635_G0.7180.28
248_I456_I0.7180.28
71_F558_Y0.7170.28
234_T313_S0.7150.28
290_K316_R0.7110.28
418_Q607_L0.7110.28
96_K111_V0.7100.28
631_F636_K0.7100.28
276_I298_W0.7090.28
47_R484_R0.7070.28
290_K314_K0.7040.28
554_D654_P0.7040.28
20_T25_D0.7040.28
606_S612_R0.7040.28
371_D461_M0.7020.27
628_N631_F0.7020.27
146_Y168_S0.7020.27
598_M601_K0.7020.27
338_I579_I0.7010.27
564_L568_E0.7000.27
445_L611_V0.7000.27
261_I630_R0.7000.27
594_R625_A0.7000.27
418_Q467_A0.6990.27
519_T524_V0.6990.27
345_V362_I0.6980.27
193_R200_R0.6970.27
197_F530_M0.6970.27
356_K522_K0.6960.27
242_S505_Q0.6950.27
304_V307_I0.6950.27
208_E229_L0.6940.27
309_G315_V0.6920.27
309_G456_I0.6910.27
253_Q321_P0.6910.27
27_T468_L0.6890.27
64_Q329_R0.6880.27
191_L194_R0.6880.27
417_V480_V0.6870.27
229_L294_D0.6870.27
248_I480_V0.6860.27
465_G560_K0.6850.27
631_F639_L0.6840.27
320_L416_I0.6840.27
279_G325_G0.6830.26
389_I614_K0.6820.26
621_A625_A0.6820.26
319_I576_N0.6810.26
219_A656_L0.6810.26
522_K550_W0.6810.26
24_E31_Q0.6780.26
138_M174_E0.6780.26
214_A222_I0.6780.26
252_L300_L0.6780.26
202_L552_S0.6780.26
185_K382_K0.6770.26
35_L210_V0.6770.26
214_A218_F0.6770.26
295_V635_G0.6770.26
48_V521_R0.6770.26
323_G623_R0.6760.26
431_D435_Q0.6760.26
212_S406_L0.6760.26
186_E514_V0.6750.26
530_M659_T0.6750.26
470_V530_M0.6750.26
463_D513_R0.6730.26
85_L296_I0.6720.26
113_Y664_L0.6720.26
309_G478_G0.6710.26
642_L645_L0.6710.26
275_A331_V0.6690.26
338_I533_G0.6690.26
147_N223_D0.6680.26
222_I504_V0.6680.26
584_E630_R0.6670.26
264_M506_Y0.6660.26
172_F612_R0.6660.26
200_R338_I0.6650.26
250_A304_V0.6650.26
122_R345_V0.6640.25
258_Y293_V0.6630.25
315_V478_G0.6630.25
335_R400_L0.6630.25
375_V447_D0.6630.25
370_T634_E0.6620.25
45_S659_T0.6620.25
211_F241_M0.6610.25
383_Q425_K0.6600.25
85_L470_V0.6600.25
50_S206_N0.6600.25
23_V28_R0.6590.25
459_A556_A0.6580.25
272_K336_E0.6580.25
578_R665_D0.6580.25
88_S91_E0.6570.25
456_I480_V0.6570.25
242_S356_K0.6570.25
570_E573_K0.6570.25
517_G522_K0.6570.25
88_S98_T0.6570.25
41_H211_F0.6560.25
322_A338_I0.6550.25
143_N359_V0.6550.25
205_T544_E0.6550.25
130_A169_K0.6530.25
469_V593_A0.6530.25
465_G660_V0.6520.25
629_E633_R0.6520.25
474_T572_L0.6510.25
272_K277_S0.6500.25
117_N331_V0.6500.25
321_P376_Q0.6490.25
468_L568_E0.6470.25
190_T281_K0.6470.25
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373_V390_I0.6470.25
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126_R179_L0.6440.24
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459_A588_I0.6430.24
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86_L89_D0.6420.24
386_S664_L0.6410.24
338_I591_D0.6400.24
22_A25_D0.6380.24
26_I34_V0.6380.24
349_V383_Q0.6370.24
112_F137_P0.6370.24
424_G614_K0.6360.24
342_D404_V0.6350.24
136_K439_K0.6340.24
247_G519_T0.6340.24
106_S574_E0.6330.24
265_V545_D0.6320.24
247_G308_K0.6320.24
514_V558_Y0.6290.24
217_A560_K0.6290.24
157_K346_K0.6280.24
21_F34_V0.6280.24
39_T125_E0.6270.24
333_L657_D0.6270.24
272_K598_M0.6270.24
360_L373_V0.6250.23
559_V636_K0.6250.23
71_F94_A0.6250.23
63_D311_K0.6250.23
408_G433_D0.6250.23
343_R406_L0.6240.23
68_A611_V0.6240.23
439_K458_A0.6240.23
246_E310_P0.6230.23
308_K478_G0.6230.23
594_R626_R0.6230.23
628_N638_E0.6230.23
231_P309_G0.6220.23
314_K514_V0.6220.23
105_R577_A0.6220.23
158_N289_G0.6200.23
319_I331_V0.6200.23
407_S457_F0.6200.23
61_D275_A0.6190.23
191_L284_G0.6190.23
576_N593_A0.6160.23
147_N604_I0.6150.23
261_I294_D0.6140.23
76_N146_Y0.6140.23
296_I570_E0.6140.23
312_G336_E0.6140.23
342_D474_T0.6140.23
601_K615_E0.6140.23
21_F24_E0.6130.23
252_L317_L0.6130.23
298_W306_L0.6120.23
26_I31_Q0.6120.23
98_T637_P0.6110.23
128_Q132_S0.6110.23
294_D304_V0.6110.23
240_E294_D0.6100.23
313_S485_S0.6080.23
236_Q486_L0.6080.23
617_N659_T0.6080.23
316_R334_T0.6080.23
245_L259_T0.6070.23
609_Y617_N0.6070.23
148_L276_I0.6060.23
313_S436_V0.6060.23
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80_Y210_V0.6050.23
236_Q405_S0.6040.22
172_F176_S0.6040.22
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257_D297_G0.6030.22
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335_R519_T0.6030.22
521_R542_K0.6020.22
133_V167_D0.6020.22
403_A407_S0.6020.22
209_D319_I0.6020.22
403_A448_R0.6020.22
446_V526_P0.6020.22
143_N214_A0.6010.22
22_A27_T0.6000.22
248_I304_V0.6000.22
219_A508_I0.6000.22
240_E482_Q0.6000.22
153_A474_T0.5990.22
215_M585_F0.5990.22
605_V638_E0.5990.22
78_L295_V0.5990.22
444_V457_F0.5980.22
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268_G518_S0.5980.22
152_K375_V0.5980.22
418_Q522_K0.5970.22
526_P539_T0.5960.22
185_K538_E0.5960.22
243_L343_R0.5960.22
654_P664_L0.5940.22
512_Y628_N0.5940.22
313_S335_R0.5930.22
120_Q590_K0.5930.22
202_L342_D0.5920.22
252_L315_V0.5900.22
71_F377_L0.5900.22
67_S71_F0.5890.22
190_T253_Q0.5890.22
134_L161_E0.5890.22
390_I556_A0.5890.22
297_G475_F0.5880.22
334_T379_K0.5880.22
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191_L195_Y0.5870.22
567_F625_A0.5870.22
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265_V308_K0.5870.22
312_G335_R0.5860.22
387_S443_V0.5860.22
74_Y255_D0.5860.22
92_Q95_K0.5860.22
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419_V509_Q0.5850.22
567_F620_D0.5840.22
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285_V309_G0.5840.22
248_I315_V0.5840.22
478_G540_G0.5840.22
84_V369_L0.5840.22
459_A513_R0.5830.21
584_E654_P0.5820.21
44_V486_L0.5800.21
113_Y448_R0.5790.21
575_H579_I0.5790.21
218_F222_I0.5780.21
349_V548_L0.5780.21
583_P628_N0.5780.21
252_L417_V0.5780.21
263_S515_N0.5770.21
519_T550_W0.5770.21
247_G313_S0.5760.21
518_S522_K0.5760.21
532_T587_N0.5760.21
454_S513_R0.5750.21
289_G334_T0.5740.21
400_L417_V0.5730.21
100_L637_P0.5730.21
74_Y311_K0.5730.21
91_E160_A0.5730.21
88_S610_A0.5720.21
25_D28_R0.5710.21
308_K315_V0.5710.21
279_G324_K0.5710.21
27_T384_N0.5700.21
419_V446_V0.5700.21
169_K300_L0.5700.21
151_S445_L0.5700.21
378_Q381_E0.5690.21
304_V417_V0.5690.21
158_N567_F0.5690.21
52_F218_F0.5690.21
421_D425_K0.5680.21
273_S419_V0.5680.21
47_R482_Q0.5670.21
592_I643_D0.5670.21
596_N600_D0.5640.21
227_N362_I0.5630.21
309_G400_L0.5630.21
75_L114_D0.5630.21
269_P510_K0.5620.21
247_G400_L0.5610.20
194_R304_V0.5610.20
201_R302_D0.5610.20
389_I659_T0.5600.20
338_I374_K0.5600.20
218_F512_Y0.5590.20
339_R612_R0.5580.20
459_A501_L0.5580.20
369_L505_Q0.5580.20
363_P466_R0.5580.20
149_D246_E0.5550.20
362_I518_S0.5550.20
48_V189_E0.5550.20
77_L474_T0.5550.20
76_N545_D0.5540.20
175_L349_V0.5530.20
212_S475_F0.5530.20
19_Q27_T0.5530.20
178_K302_D0.5530.20
295_V298_W0.5510.20
325_G525_T0.5510.20
121_K338_I0.5510.20
274_K355_E0.5500.20
349_V388_V0.5500.20
461_M473_P0.5500.20
37_E443_V0.5490.20
428_E517_G0.5490.20
331_V569_P0.5480.20
588_I655_Y0.5480.20
181_G549_P0.5480.20
584_E634_E0.5480.20
590_K593_A0.5480.20
261_I524_V0.5470.20
311_K514_V0.5470.20
250_A276_I0.5460.20
144_D214_A0.5450.20
401_T420_R0.5450.20
234_T503_S0.5440.20
210_V482_Q0.5440.20
229_L367_V0.5430.20
285_V317_L0.5430.20
445_L511_F0.5430.20
241_M480_V0.5420.20
458_A479_T0.5420.20
99_E102_D0.5420.20
150_R269_P0.5410.20
193_R256_D0.5410.20
78_L115_L0.5410.20
264_M529_I0.5410.20
140_F188_R0.5400.20
28_R31_Q0.5400.20
241_M252_L0.5400.20
169_K336_E0.5400.20
302_D501_L0.5390.20
179_L295_V0.5390.20
407_S467_A0.5380.19
63_D171_K0.5380.19
47_R508_I0.5380.19
84_V616_N0.5380.19
114_D118_L0.5380.19
132_S153_A0.5370.19
75_L531_P0.5370.19
449_F512_Y0.5360.19
580_A638_E0.5350.19
147_N603_N0.5350.19
184_D389_I0.5340.19
374_K378_Q0.5340.19
48_V385_V0.5340.19
250_A299_R0.5340.19
90_V341_E0.5340.19
552_S555_A0.5340.19
259_T294_D0.5330.19
316_R467_A0.5330.19
289_G314_K0.5330.19
588_I594_R0.5330.19
445_L659_T0.5330.19
290_K605_V0.5320.19
162_L341_E0.5320.19
197_F301_D0.5310.19
66_F521_R0.5300.19
70_I192_T0.5300.19
275_A577_A0.5290.19
121_K568_E0.5290.19
80_Y296_I0.5280.19
22_A469_V0.5280.19
175_L178_K0.5280.19
148_L608_N0.5270.19
460_A478_G0.5270.19
44_V82_H0.5270.19
119_A123_R0.5270.19
89_D502_G0.5270.19
245_L593_A0.5260.19
228_Y426_V0.5260.19
296_I635_G0.5250.19
275_A620_D0.5250.19
231_P502_G0.5250.19
556_A620_D0.5240.19
309_G519_T0.5240.19
117_N128_Q0.5240.19
46_E146_Y0.5240.19
309_G312_G0.5240.19
222_I626_R0.5230.19
647_K655_Y0.5230.19
229_L475_F0.5220.19
247_G480_V0.5220.19
295_V593_A0.5220.19
448_R542_K0.5220.19
465_G561_S0.5210.19
269_P475_F0.5210.19
323_G552_S0.5210.19
487_N666_L0.5210.19
303_V448_R0.5200.19
187_I472_E0.5200.19
582_D587_N0.5190.19
487_N500_A0.5190.19
262_N512_Y0.5190.19
283_V320_L0.5190.19
447_D542_K0.5180.19
381_E622_T0.5180.19
20_T34_V0.5180.19
156_P165_L0.5180.19
285_V333_L0.5180.19
291_P316_R0.5180.19
175_L606_S0.5170.19
48_V306_L0.5170.19
21_F290_K0.5150.19
444_V547_A0.5150.19
22_A26_I0.5150.19
472_E609_Y0.5150.19
363_P415_P0.5140.18
276_I338_I0.5140.18
421_D530_M0.5130.18
315_V480_V0.5130.18
62_L233_N0.5120.18
575_H665_D0.5120.18
250_A345_V0.5110.18
109_L547_A0.5110.18
104_L487_N0.5110.18
542_K587_N0.5100.18
620_D624_L0.5100.18
320_L659_T0.5100.18
337_R575_H0.5100.18
204_Q235_E0.5090.18
290_K640_K0.5090.18
300_L317_L0.5090.18
570_E621_A0.5090.18
239_T276_I0.5080.18
377_L605_V0.5080.18
272_K294_D0.5080.18
335_R480_V0.5070.18
444_V571_L0.5070.18
71_F114_D0.5070.18
234_T509_Q0.5070.18
570_E604_I0.5070.18
112_F227_N0.5060.18
631_F635_G0.5060.18
290_K357_V0.5060.18
378_Q437_F0.5050.18
472_E532_T0.5050.18
484_R506_Y0.5050.18
442_L548_L0.5050.18
176_S319_I0.5050.18
376_Q380_L0.5040.18
135_E382_K0.5040.18
421_D654_P0.5040.18
341_E444_V0.5040.18
145_T468_L0.5030.18
454_S466_R0.5020.18
274_K430_S0.5020.18
268_G340_L0.5020.18
83_N156_P0.5020.18
217_A310_P0.5010.18
90_V118_L0.5010.18
632_K635_G0.5010.18
139_D151_S0.5010.18
478_G519_T0.5000.18
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4ql6A 2 0.673 100 0.451 Contact Map
1fc6A 1 0.544 100 0.698 Contact Map
4c2eA 2 0.5997 100 0.707 Contact Map
3k50A 1 0.5073 100 0.713 Contact Map
4lurA 1 0.4311 100 0.746 Contact Map
1k32A 5 0.6906 100 0.756 Contact Map
4ghnA 1 0.5367 100 0.759 Contact Map
3dorA 2 0.5455 100 0.761 Contact Map
1j7xA 1 0.4223 100 0.779 Contact Map
4l8kA 3 0.4428 100 0.81 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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