TRKG - ECOLI - GREMLIN Contacts

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TRKG - Trk system potassium uptake protein TrkG

UniProt:	P23849	Sequences: MNTSHVRVVTHMCGFLVWLYSLSMLPPMVVALFYKEKSLFVFFITFVIFFCIGGGAWYTTKKSGIQLRTRDGFIIIVMFWILFSVISAFPLWIDSELNLTFIDALFEGVSGITTTGATVIDDVSSLPRAYLYYRSQLNFIGGLGVIVLAVAVLPLLGIGGAKLYQSEMPGPFKDDKLTPRLADTSRTLWITYSLLGIACIVCYRLAGMPLFDAICHGISTVSLGGFSTHSESIGYFNNYLVELVAGSFSLLSAFNFTLWYIVISRKTIKPLIRDIELRFFLLIALGVIIVTSFQVWHIGMYDLHGSFIHSFFLASSMLTDNGLATQDYASWPTHTIVFLLLSSFFGGCIGSTCGGIKSLRFLILFKQSKHEINQLSHPRALLSVNVGGKIVTDRVMRSVWSFFFLYTLFTVFFILVLNGMGYDFLTSFATVAACINNMGLGFGATASSFGVLNDIAKCLMCIAMILGRLEIYPVIILFSGFFWRS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11020
Length:	485 (404)
Sequences:	5282 (3952)
Seq/√Len:	196.6

ECOLI - TRKG TRKH
BACSU - KTRB KTRD
HALSA - Q9HMF7 Q9HQ81 Q9HPA9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
413_F	463_A	4.252	1.00
347_G	353_C	4.227	1.00
103_D	457_K	3.471	1.00
200_I	214_I	3.403	1.00
246_G	311_F	3.400	1.00
102_I	458_C	3.212	1.00
203_Y	245_A	3.154	1.00
199_C	248_F	2.953	1.00
139_F	196_G	2.933	1.00
416_V	459_L	2.778	1.00
206_A	238_N	2.722	1.00
327_D	330_S	2.639	1.00
348_C	358_S	2.497	1.00
417_L	456_A	2.472	1.00
229_H	235_Y	2.416	1.00
138_N	219_S	2.396	1.00
231_E	235_Y	2.384	1.00
202_C	244_V	2.367	1.00
423_D	426_T	2.356	1.00
206_A	240_L	2.329	1.00
105_L	461_C	2.317	1.00
135_S	215_C	2.286	1.00
67_L	71_D	2.276	1.00
302_D	305_G	2.231	1.00
128_R	132_Y	2.153	1.00
204_R	210_L	2.144	1.00
102_I	461_C	2.114	1.00
131_L	211_F	2.102	1.00
109_V	461_C	2.088	1.00
206_A	244_V	2.045	1.00
318_L	339_L	2.044	1.00
200_I	210_L	2.040	1.00
219_S	323_L	2.033	1.00
216_H	227_S	2.024	1.00
414_I	428_F	1.972	1.00
291_T	295_V	1.948	1.00
242_E	308_I	1.947	1.00
242_E	309_H	1.943	1.00
99_L	125_S	1.932	1.00
129_A	133_Y	1.896	1.00
246_G	315_S	1.888	1.00
121_D	124_S	1.879	1.00
206_A	241_V	1.866	1.00
68_R	71_D	1.849	1.00
204_R	213_A	1.847	1.00
102_I	454_D	1.845	1.00
253_A	319_T	1.826	1.00
250_L	315_S	1.806	1.00
240_L	244_V	1.776	1.00
416_V	455_I	1.774	1.00
233_I	245_A	1.766	1.00
100_T	103_D	1.758	1.00
304_H	308_I	1.757	1.00
202_C	240_L	1.743	1.00
84_S	101_F	1.735	1.00
221_V	252_S	1.734	1.00
364_L	403_F	1.733	1.00
243_L	247_S	1.729	1.00
340_L	432_A	1.720	1.00
253_A	280_F	1.708	1.00
118_T	122_D	1.703	1.00
413_F	459_L	1.693	1.00
239_Y	308_I	1.675	1.00
282_L	286_G	1.661	1.00
242_E	325_T	1.661	1.00
410_T	432_A	1.645	1.00
289_I	338_F	1.640	1.00
88_A	101_F	1.630	1.00
433_A	438_M	1.610	1.00
243_L	308_I	1.600	1.00
363_I	391_V	1.598	1.00
229_H	236_F	1.563	1.00
122_D	125_S	1.540	1.00
410_T	435_I	1.530	1.00
356_I	361_F	1.520	1.00
186_R	190_I	1.520	1.00
420_M	453_N	1.515	1.00
237_N	309_H	1.505	1.00
220_T	245_A	1.504	1.00
426_T	442_F	1.499	1.00
290_V	335_T	1.497	1.00
200_I	217_G	1.490	1.00
249_S	316_S	1.490	1.00
249_S	321_N	1.485	1.00
285_L	289_I	1.478	1.00
369_K	373_N	1.477	1.00
203_Y	241_V	1.476	1.00
320_D	438_M	1.458	1.00
67_L	70_R	1.443	1.00
414_I	431_V	1.441	1.00
110_S	226_F	1.440	1.00
458_C	462_I	1.437	1.00
88_A	92_W	1.437	1.00
247_S	251_L	1.435	1.00
99_L	126_L	1.429	1.00
243_L	304_H	1.421	1.00
92_W	129_A	1.416	1.00
107_E	119_V	1.414	1.00
215_C	228_T	1.410	1.00
138_N	224_G	1.401	1.00
314_A	318_L	1.401	1.00
102_I	457_K	1.389	1.00
275_I	279_F	1.389	1.00
406_Y	435_I	1.377	1.00
131_L	135_S	1.370	1.00
441_G	445_T	1.361	1.00
101_F	105_L	1.356	1.00
341_L	345_F	1.352	1.00
283_I	315_S	1.351	1.00
208_M	241_V	1.350	1.00
458_C	461_C	1.349	1.00
212_D	229_H	1.347	1.00
328_Y	339_L	1.336	1.00
422_Y	444_A	1.334	1.00
202_C	206_A	1.333	1.00
109_V	465_I	1.332	1.00
84_S	109_V	1.331	1.00
345_F	358_S	1.327	1.00
105_L	458_C	1.325	1.00
99_L	120_I	1.318	1.00
208_M	212_D	1.301	1.00
274_D	278_R	1.296	1.00
123_V	230_S	1.295	1.00
250_L	281_L	1.292	1.00
220_T	323_L	1.285	1.00
430_T	445_T	1.282	1.00
243_L	311_F	1.280	1.00
111_G	226_F	1.277	1.00
210_L	214_I	1.265	1.00
243_L	307_F	1.259	1.00
294_Q	335_T	1.257	1.00
313_L	325_T	1.255	1.00
422_Y	427_S	1.254	1.00
234_G	324_A	1.254	1.00
108_G	137_L	1.253	1.00
340_L	428_F	1.250	1.00
128_R	211_F	1.243	1.00
204_R	209_P	1.243	1.00
199_C	217_G	1.240	1.00
383_S	390_I	1.239	1.00
413_F	431_V	1.236	1.00
414_I	427_S	1.227	1.00
283_I	287_V	1.224	1.00
216_H	228_T	1.214	1.00
97_L	127_P	1.213	1.00
295_V	306_S	1.211	1.00
103_D	119_V	1.211	1.00
91_L	137_L	1.208	1.00
344_F	410_T	1.208	1.00
122_D	230_S	1.206	1.00
303_L	307_F	1.205	1.00
336_I	442_F	1.198	1.00
345_F	361_F	1.197	1.00
291_T	294_Q	1.190	1.00
84_S	105_L	1.188	1.00
462_I	466_L	1.176	1.00
234_G	327_D	1.174	1.00
126_L	134_R	1.172	1.00
70_R	74_I	1.167	1.00
121_D	230_S	1.163	1.00
328_Y	331_W	1.157	1.00
105_L	109_V	1.155	1.00
100_T	454_D	1.154	1.00
290_V	339_L	1.154	1.00
195_L	251_L	1.154	1.00
410_T	414_I	1.152	1.00
239_Y	242_E	1.149	1.00
431_V	463_A	1.147	1.00
286_G	314_A	1.142	1.00
367_Q	400_W	1.141	1.00
452_L	460_M	1.133	1.00
70_R	73_F	1.132	1.00
135_S	214_I	1.131	1.00
309_H	326_Q	1.126	1.00
237_N	242_E	1.124	1.00
182_A	186_R	1.121	1.00
275_I	278_R	1.118	1.00
242_E	246_G	1.116	1.00
135_S	211_F	1.111	1.00
249_S	315_S	1.110	1.00
309_H	313_L	1.102	1.00
363_I	396_M	1.101	1.00
305_G	309_H	1.097	1.00
328_Y	442_F	1.088	1.00
132_Y	136_Q	1.088	1.00
84_S	88_A	1.084	1.00
340_L	429_A	1.082	1.00
220_T	248_F	1.081	1.00
195_L	259_W	1.079	1.00
292_S	295_V	1.075	1.00
243_L	246_G	1.060	1.00
393_D	397_R	1.057	1.00
279_F	362_L	1.055	1.00
201_V	205_L	1.051	1.00
332_P	335_T	1.051	1.00
286_G	294_Q	1.049	1.00
420_M	456_A	1.048	1.00
71_D	74_I	1.047	1.00
301_Y	309_H	1.043	1.00
349_I	359_L	1.040	1.00
363_I	399_V	1.024	1.00
231_E	234_G	1.021	1.00
287_V	291_T	1.021	1.00
271_L	275_I	1.021	1.00
291_T	306_S	1.021	1.00
258_L	274_D	1.015	1.00
120_I	126_L	1.014	1.00
269_K	273_R	1.014	1.00
284_A	318_L	1.013	1.00
135_S	218_I	1.013	1.00
287_V	342_S	1.008	1.00
292_S	296_W	1.007	1.00
196_G	217_G	1.007	1.00
199_C	245_A	1.007	1.00
254_F	277_L	1.007	1.00
265_R	268_I	1.003	1.00
293_F	296_W	0.997	1.00
239_Y	243_L	0.994	1.00
282_L	294_Q	0.992	1.00
452_L	456_A	0.991	1.00
371_E	397_R	0.991	1.00
453_N	456_A	0.990	1.00
403_F	407_T	0.990	1.00
434_C	460_M	0.989	1.00
87_S	108_G	0.985	1.00
203_Y	244_V	0.985	1.00
288_I	292_S	0.984	1.00
431_V	460_M	0.976	0.99
272_I	276_E	0.976	0.99
209_P	213_A	0.973	0.99
239_Y	304_H	0.973	0.99
417_L	431_V	0.973	0.99
91_L	129_A	0.972	0.99
277_L	281_L	0.971	0.99
409_F	466_L	0.969	0.99
334_H	415_L	0.969	0.99
128_R	131_L	0.969	0.99
281_L	362_L	0.969	0.99
418_N	427_S	0.965	0.99
227_S	232_S	0.963	0.99
287_V	314_A	0.962	0.99
199_C	244_V	0.961	0.99
271_L	274_D	0.958	0.99
291_T	310_S	0.958	0.99
276_E	279_F	0.957	0.99
414_I	424_F	0.956	0.99
250_L	284_A	0.952	0.99
258_L	277_L	0.951	0.99
199_C	203_Y	0.951	0.99
122_D	126_L	0.951	0.99
336_I	426_T	0.950	0.99
274_D	387_G	0.949	0.99
77_V	465_I	0.942	0.99
309_H	325_T	0.941	0.99
273_R	276_E	0.933	0.99
203_Y	220_T	0.931	0.99
111_G	134_R	0.926	0.99
107_E	134_R	0.923	0.99
227_S	230_S	0.922	0.99
233_I	241_V	0.921	0.99
143_L	189_W	0.921	0.99
456_A	460_M	0.915	0.99
132_Y	211_F	0.915	0.99
365_F	369_K	0.913	0.99
93_I	98_N	0.913	0.99
417_L	460_M	0.912	0.99
216_H	229_H	0.911	0.99
93_I	99_L	0.908	0.99
329_A	336_I	0.907	0.99
119_V	122_D	0.907	0.99
237_N	301_Y	0.906	0.99
409_F	463_A	0.906	0.99
420_M	455_I	0.906	0.99
92_W	101_F	0.902	0.99
366_K	386_V	0.901	0.99
228_T	236_F	0.898	0.99
430_T	441_G	0.896	0.99
190_I	194_L	0.892	0.99
199_C	220_T	0.890	0.99
107_E	122_D	0.890	0.99
338_F	415_L	0.887	0.99
124_S	230_S	0.884	0.99
455_I	459_L	0.884	0.99
122_D	134_R	0.882	0.99
224_G	320_D	0.881	0.99
289_I	293_F	0.881	0.99
313_L	339_L	0.880	0.99
343_S	438_M	0.880	0.99
261_I	272_I	0.876	0.99
205_L	240_L	0.874	0.99
251_L	259_W	0.873	0.99
92_W	127_P	0.872	0.99
273_R	279_F	0.872	0.99
250_L	283_I	0.870	0.99
135_S	138_N	0.868	0.99
109_V	474_V	0.864	0.99
290_V	294_Q	0.858	0.99
94_D	127_P	0.855	0.99
279_F	358_S	0.851	0.99
89_F	93_I	0.848	0.99
344_F	406_Y	0.845	0.98
433_A	441_G	0.845	0.98
94_D	131_L	0.844	0.98
329_A	442_F	0.842	0.98
79_F	112_I	0.840	0.98
75_I	145_V	0.839	0.98
333_T	425_L	0.838	0.98
138_N	222_S	0.838	0.98
195_L	221_V	0.835	0.98
373_N	382_L	0.834	0.98
286_G	293_F	0.827	0.98
283_I	286_G	0.820	0.98
166_S	180_R	0.819	0.98
87_S	90_P	0.816	0.98
274_D	279_F	0.812	0.98
287_V	294_Q	0.811	0.98
180_R	183_D	0.811	0.98
278_R	281_L	0.810	0.98
117_A	433_A	0.800	0.98
268_I	271_L	0.800	0.98
135_S	219_S	0.796	0.98
200_I	204_R	0.791	0.98
370_H	384_V	0.790	0.98
405_L	472_Y	0.789	0.98
203_Y	233_I	0.789	0.98
366_K	384_V	0.789	0.98
270_P	273_R	0.789	0.98
368_S	405_L	0.789	0.98
96_E	127_P	0.785	0.98
197_I	201_V	0.785	0.98
238_N	242_E	0.783	0.98
80_W	112_I	0.783	0.98
271_L	277_L	0.782	0.97
435_I	463_A	0.781	0.97
148_L	189_W	0.779	0.97
201_V	204_R	0.779	0.97
101_F	458_C	0.779	0.97
259_W	271_L	0.777	0.97
209_P	212_D	0.777	0.97
349_I	358_S	0.775	0.97
301_Y	306_S	0.774	0.97
288_I	311_F	0.773	0.97
364_L	368_S	0.771	0.97
340_L	425_L	0.769	0.97
314_A	342_S	0.769	0.97
287_V	307_F	0.764	0.97
238_N	241_V	0.764	0.97
301_Y	305_G	0.761	0.97
288_I	295_V	0.760	0.97
272_I	275_I	0.757	0.97
194_L	198_A	0.752	0.97
223_L	319_T	0.751	0.97
246_G	250_L	0.750	0.97
273_R	278_R	0.743	0.97
212_D	216_H	0.743	0.97
209_P	236_F	0.742	0.97
285_L	288_I	0.741	0.97
367_Q	396_M	0.739	0.96
275_I	387_G	0.736	0.96
107_E	118_T	0.736	0.96
368_S	401_S	0.735	0.96
112_I	137_L	0.735	0.96
304_H	307_F	0.734	0.96
215_C	219_S	0.730	0.96
282_L	291_T	0.728	0.96
233_I	236_F	0.728	0.96
272_I	278_R	0.728	0.96
246_G	287_V	0.727	0.96
313_L	328_Y	0.725	0.96
343_S	433_A	0.724	0.96
291_T	303_L	0.719	0.96
471_I	475_I	0.718	0.96
187_T	260_Y	0.715	0.96
337_V	424_F	0.715	0.96
426_T	444_A	0.714	0.96
276_E	281_L	0.712	0.96
278_R	348_C	0.712	0.96
284_A	287_V	0.709	0.96
432_A	436_N	0.709	0.96
83_F	137_L	0.708	0.95
83_F	87_S	0.707	0.95
297_H	301_Y	0.707	0.95
277_L	362_L	0.705	0.95
364_L	404_F	0.703	0.95
283_I	358_S	0.703	0.95
418_N	424_F	0.699	0.95
183_D	186_R	0.698	0.95
427_S	444_A	0.697	0.95
253_A	347_G	0.695	0.95
272_I	279_F	0.693	0.95
288_I	294_Q	0.692	0.95
127_P	130_Y	0.691	0.95
331_W	335_T	0.690	0.95
444_A	447_S	0.687	0.95
117_A	434_C	0.686	0.95
80_W	109_V	0.686	0.95
216_H	245_A	0.685	0.95
85_V	105_L	0.685	0.95
326_Q	331_W	0.683	0.95
138_N	218_I	0.682	0.94
414_I	418_N	0.680	0.94
311_F	315_S	0.676	0.94
102_I	460_M	0.676	0.94
118_T	134_R	0.675	0.94
223_L	252_S	0.674	0.94
303_L	306_S	0.674	0.94
417_L	427_S	0.673	0.94
196_G	200_I	0.671	0.94
106_F	119_V	0.670	0.94
191_T	195_L	0.670	0.94
288_I	291_T	0.668	0.94
324_A	327_D	0.667	0.94
118_T	123_V	0.667	0.94
274_D	277_L	0.666	0.94
300_M	306_S	0.663	0.94
445_T	452_L	0.663	0.94
124_S	229_H	0.662	0.94
286_G	290_V	0.660	0.93
120_I	125_S	0.659	0.93
406_Y	436_N	0.658	0.93
429_A	440_L	0.658	0.93
223_L	352_T	0.657	0.93
240_L	243_L	0.655	0.93
74_I	78_M	0.653	0.93
216_H	323_L	0.653	0.93
289_I	292_S	0.651	0.93
257_T	350_G	0.651	0.93
454_D	457_K	0.649	0.93
370_H	393_D	0.649	0.93
210_L	213_A	0.646	0.93
199_C	202_C	0.645	0.93
457_K	461_C	0.643	0.93
419_G	453_N	0.643	0.93
368_S	404_F	0.642	0.93
68_R	73_F	0.641	0.92
366_K	369_K	0.641	0.92
73_F	465_I	0.639	0.92
254_F	259_W	0.637	0.92
425_L	442_F	0.636	0.92
89_F	129_A	0.634	0.92
410_T	428_F	0.634	0.92
295_V	303_L	0.634	0.92
292_S	307_F	0.632	0.92
93_I	125_S	0.632	0.92
271_L	276_E	0.631	0.92
242_E	313_L	0.631	0.92
138_N	323_L	0.631	0.92
205_L	213_A	0.630	0.92
424_F	427_S	0.630	0.92
441_G	446_A	0.628	0.92
259_W	263_I	0.628	0.92
466_L	474_V	0.628	0.92
234_G	237_N	0.627	0.92
286_G	296_W	0.625	0.92
94_D	130_Y	0.624	0.91
280_F	387_G	0.624	0.91
307_F	311_F	0.624	0.91
333_T	336_I	0.623	0.91
268_I	272_I	0.622	0.91
211_F	215_C	0.621	0.91
104_A	108_G	0.619	0.91
286_G	289_I	0.619	0.91
324_A	440_L	0.618	0.91
313_L	316_S	0.618	0.91
191_T	259_W	0.617	0.91
77_V	81_I	0.616	0.91
85_V	101_F	0.615	0.91
277_L	366_K	0.614	0.91
117_A	441_G	0.613	0.91
67_L	74_I	0.612	0.91
287_V	310_S	0.612	0.91
429_A	441_G	0.611	0.91
207_G	211_F	0.611	0.91
282_L	287_V	0.609	0.90
428_F	432_A	0.606	0.90
422_Y	452_L	0.604	0.90
117_A	440_L	0.599	0.90
337_V	414_I	0.599	0.90
123_V	131_L	0.599	0.90
329_A	447_S	0.597	0.90
232_S	438_M	0.596	0.90
287_V	295_V	0.596	0.90
192_Y	222_S	0.596	0.90
217_G	248_F	0.595	0.89
364_L	400_W	0.595	0.89
223_L	321_N	0.594	0.89
197_I	200_I	0.592	0.89
100_T	104_A	0.592	0.89
234_G	325_T	0.591	0.89
233_I	242_E	0.589	0.89
196_G	218_I	0.589	0.89
410_T	431_V	0.588	0.89
316_S	440_L	0.585	0.89
196_G	221_V	0.578	0.88
258_L	278_R	0.575	0.88
114_T	320_D	0.575	0.88
320_D	354_G	0.572	0.88
80_W	113_T	0.572	0.88
89_F	92_W	0.572	0.88
212_D	228_T	0.569	0.87
77_V	474_V	0.569	0.87
275_I	362_L	0.568	0.87
356_I	403_F	0.568	0.87
430_T	440_L	0.568	0.87
312_F	323_L	0.568	0.87
371_E	401_S	0.567	0.87
408_L	412_F	0.565	0.87
262_V	271_L	0.565	0.87
288_I	296_W	0.565	0.87
156_L	159_G	0.564	0.87
381_L	385_N	0.563	0.87
88_A	98_N	0.563	0.87
195_L	252_S	0.562	0.87
255_N	276_E	0.562	0.87
290_V	334_H	0.560	0.86
314_A	339_L	0.560	0.86
337_V	341_L	0.559	0.86
114_T	223_L	0.558	0.86
283_I	318_L	0.558	0.86
118_T	219_S	0.557	0.86
347_G	358_S	0.556	0.86
270_P	276_E	0.555	0.86
435_I	471_I	0.554	0.86
117_A	445_T	0.553	0.86
318_L	342_S	0.552	0.86
430_T	460_M	0.551	0.86
84_S	108_G	0.550	0.85
143_L	188_L	0.550	0.85
206_A	236_F	0.549	0.85
184_T	351_S	0.548	0.85
282_L	295_V	0.546	0.85
430_T	433_A	0.546	0.85
132_Y	135_S	0.545	0.85
429_A	433_A	0.545	0.85
283_I	345_F	0.545	0.85
272_I	277_L	0.544	0.85
320_D	323_L	0.544	0.85
113_T	354_G	0.544	0.85
81_I	84_S	0.543	0.85
313_L	331_W	0.542	0.85
340_L	344_F	0.542	0.85
298_I	301_Y	0.541	0.85
427_S	431_V	0.540	0.84
352_T	357_K	0.540	0.84
145_V	185_S	0.538	0.84
194_L	197_I	0.537	0.84
98_N	119_V	0.536	0.84
393_D	396_M	0.535	0.84
287_V	311_F	0.534	0.84
409_F	435_I	0.534	0.84
178_T	184_T	0.533	0.84
232_S	236_F	0.533	0.84
75_I	79_F	0.533	0.84
340_L	442_F	0.532	0.84
422_Y	426_T	0.531	0.83
233_I	312_F	0.530	0.83
78_M	82_L	0.530	0.83
99_L	103_D	0.530	0.83
454_D	458_C	0.529	0.83
218_I	222_S	0.528	0.83
443_G	447_S	0.528	0.83
96_E	99_L	0.528	0.83
177_L	184_T	0.527	0.83
316_S	321_N	0.527	0.83
120_I	123_V	0.527	0.83
343_S	436_N	0.526	0.83
409_F	413_F	0.525	0.83
254_F	280_F	0.525	0.83
100_T	457_K	0.524	0.83
372_I	479_S	0.524	0.83
341_L	411_V	0.523	0.82
203_Y	323_L	0.522	0.82
76_I	80_W	0.521	0.82
249_S	314_A	0.520	0.82
117_A	430_T	0.520	0.82
230_S	234_G	0.519	0.82
267_T	270_P	0.519	0.82
324_A	328_Y	0.517	0.82
269_K	274_D	0.517	0.82
189_W	193_S	0.517	0.82
215_C	221_V	0.516	0.82
269_K	272_I	0.516	0.82
85_V	88_A	0.516	0.82
205_L	209_P	0.515	0.82
161_A	182_A	0.514	0.81
334_H	419_G	0.514	0.81
320_D	435_I	0.514	0.81
192_Y	196_G	0.513	0.81
139_F	218_I	0.512	0.81
283_I	294_Q	0.512	0.81
406_Y	410_T	0.511	0.81
153_L	477_L	0.509	0.81
277_L	280_F	0.508	0.81
219_S	438_M	0.508	0.81
284_A	295_V	0.507	0.81
286_G	295_V	0.506	0.80
146_I	452_L	0.506	0.80
125_S	128_R	0.505	0.80
169_P	181_L	0.504	0.80
405_L	409_F	0.504	0.80
230_S	235_Y	0.502	0.80
363_I	367_Q	0.502	0.80
120_I	134_R	0.502	0.80
119_V	457_K	0.502	0.80
419_G	456_A	0.501	0.80
400_W	404_F	0.500	0.80

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3pjzA	2	0.9588	100	0.087	Contact Map
4j7cI	2	0.8206	100	0.307	Contact Map
3ukmA	2	0.4701	93	0.953	Contact Map
4bw5A	2	0.4866	91.3	0.955	Contact Map
3vouA	4	0.268	82.7	0.961	Contact Map
4twkA	2	0.4845	81.3	0.961	Contact Map
2a9hA	4	0.1794	79.4	0.962	Contact Map
1lnqA	6	0.1629	78.8	0.962	Contact Map
2ih3C	4	0.1773	77.4	0.963	Contact Map
2q67A	3	0.2144	76.6	0.963	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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