GREMLIN Database
HYFB - Hydrogenase-4 component B
UniProt: P23482 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11282
Length: 672 (599)
Sequences: 7284 (4341)
Seq/√Len: 177.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
193_D196_S4.3481.00
303_L371_M4.1481.00
127_A140_L3.9941.00
78_D260_K3.9831.00
191_S196_S3.6501.00
368_T373_K3.4311.00
40_L93_V3.3261.00
384_T469_E3.2151.00
134_A261_V3.2001.00
385_A456_C3.1101.00
225_M285_I3.0101.00
298_Q372_E2.9311.00
212_L216_F2.8661.00
153_I164_G2.8471.00
354_L391_G2.8111.00
389_L451_Y2.7931.00
134_A197_F2.7891.00
371_M454_T2.7491.00
85_V126_V2.7381.00
317_L436_L2.6891.00
361_A470_V2.6461.00
258_I316_L2.6031.00
85_V130_V2.5841.00
170_I229_S2.5841.00
388_C450_M2.5401.00
393_L398_I2.5401.00
43_G90_L2.5251.00
378_A385_A2.4791.00
188_E210_V2.4321.00
609_K613_H2.4271.00
344_H406_S2.4241.00
166_L233_R2.3911.00
364_S468_Q2.3601.00
385_A451_Y2.3481.00
158_K236_P2.3461.00
131_M136_W2.3421.00
181_A217_G2.3041.00
184_L210_V2.2941.00
347_N402_N2.2831.00
472_N476_V2.2301.00
464_A467_A2.2191.00
15_L123_A2.2051.00
610_G614_V2.1891.00
87_V349_A2.1821.00
18_S21_S2.1311.00
18_S22_L2.1211.00
304_L359_A2.0991.00
392_C447_F2.0981.00
177_L216_F2.0681.00
251_V308_T2.0271.00
101_T473_T2.0031.00
343_F406_S2.0001.00
319_V341_A1.9821.00
88_I129_L1.9791.00
50_G54_L1.9631.00
191_S197_F1.9631.00
259_L319_V1.9581.00
220_A227_L1.9471.00
208_S274_W1.9421.00
609_K614_V1.9411.00
365_R381_M1.9231.00
205_G209_A1.9201.00
63_R72_D1.9111.00
43_G47_I1.9101.00
363_I369_H1.9071.00
258_I266_L1.9061.00
542_P546_G1.8821.00
198_R264_D1.8731.00
144_M250_M1.8551.00
160_S236_P1.8541.00
590_V595_F1.8401.00
411_W436_L1.8261.00
83_F346_L1.8201.00
40_L44_V1.8201.00
76_R79_S1.8091.00
17_A38_T1.7931.00
381_M384_T1.7871.00
255_I316_L1.7801.00
548_Y552_C1.7771.00
358_G388_C1.7551.00
283_G320_G1.7501.00
92_V122_I1.7391.00
134_A182_F1.7251.00
44_V48_I1.7191.00
180_I213_L1.7131.00
159_T162_N1.7071.00
595_F600_Q1.7061.00
298_Q370_D1.6991.00
43_G89_S1.6941.00
99_S114_M1.6931.00
502_I506_F1.6851.00
36_G97_L1.6831.00
434_V438_V1.6731.00
110_G113_A1.6571.00
375_G457_G1.6511.00
387_A479_L1.6501.00
93_V97_L1.6461.00
284_A435_M1.6441.00
392_C451_Y1.6371.00
532_S535_L1.6371.00
383_W479_L1.6361.00
46_G85_V1.6121.00
299_D369_H1.6021.00
505_A509_T1.5911.00
296_A591_F1.5911.00
376_A457_G1.5901.00
295_L445_M1.5891.00
448_V452_G1.5851.00
580_G584_M1.5841.00
219_G282_I1.5781.00
544_L548_Y1.5661.00
106_Y155_R1.5601.00
124_S143_M1.5581.00
212_L278_L1.5491.00
390_I482_A1.5421.00
63_R66_P1.5411.00
371_M453_I1.5371.00
165_M169_F1.5321.00
588_R592_S1.5311.00
39_S42_G1.5251.00
292_L595_F1.5221.00
430_P434_V1.5161.00
287_A439_T1.4921.00
611_L614_V1.4911.00
596_R600_Q1.4881.00
483_A487_L1.4661.00
211_F275_W1.4601.00
387_A482_A1.4581.00
215_F279_V1.4551.00
594_L599_Q1.4471.00
412_Q416_S1.4461.00
22_L25_L1.4451.00
132_D195_A1.4401.00
285_I431_I1.4361.00
291_V310_E1.4311.00
547_L551_W1.4251.00
377_L381_M1.4191.00
585_Q589_V1.4141.00
307_S446_C1.4141.00
536_L540_A1.4121.00
528_Q533_L1.4011.00
215_F275_W1.3911.00
189_S197_F1.3861.00
270_G274_W1.3861.00
74_T132_D1.3821.00
256_F260_K1.3811.00
538_L542_P1.3811.00
471_P474_M1.3781.00
533_L536_L1.3761.00
506_F509_T1.3761.00
505_A510_P1.3741.00
125_M250_M1.3741.00
366_L374_M1.3691.00
593_A600_Q1.3681.00
529_V533_L1.3671.00
83_F342_L1.3661.00
280_M432_A1.3601.00
71_A135_F1.3581.00
535_L539_L1.3551.00
185_M197_F1.3551.00
259_L342_L1.3551.00
39_S43_G1.3491.00
225_M289_L1.3491.00
411_W440_G1.3441.00
610_G613_H1.3401.00
600_Q604_T1.3291.00
451_Y456_C1.3131.00
81_S256_F1.3111.00
383_W475_I1.3101.00
89_S126_V1.3051.00
65_A71_A1.2971.00
321_V414_L1.2951.00
279_V320_G1.2941.00
546_G550_L1.2871.00
45_I49_S1.2861.00
288_L435_M1.2861.00
500_M504_H1.2851.00
211_F265_L1.2841.00
390_I486_V1.2831.00
596_R599_Q1.2821.00
532_S536_L1.2801.00
365_R468_Q1.2751.00
13_L17_A1.2731.00
194_F198_R1.2711.00
503_A507_T1.2661.00
44_V47_I1.2661.00
101_T471_P1.2661.00
14_Y18_S1.2631.00
344_H351_F1.2571.00
475_I479_L1.2571.00
594_L598_R1.2561.00
78_D81_S1.2541.00
77_M81_S1.2541.00
609_K612_A1.2511.00
184_L209_A1.2481.00
311_N443_A1.2451.00
650_G655_Y1.2441.00
601_L605_L1.2371.00
370_D373_K1.2331.00
380_R465_E1.2321.00
291_V439_T1.2321.00
376_A459_P1.2291.00
87_V346_L1.2281.00
395_I447_F1.2281.00
540_A544_L1.2271.00
43_G46_G1.2131.00
479_L483_A1.2101.00
351_F403_G1.2101.00
74_T193_D1.2091.00
211_F266_L1.2051.00
135_F192_L1.2041.00
400_P405_I1.2021.00
191_S194_F1.2021.00
281_A285_I1.1941.00
380_R467_A1.1921.00
30_L33_K1.1901.00
593_A596_R1.1881.00
580_G590_V1.1881.00
584_M590_V1.1871.00
543_L547_L1.1851.00
579_S583_V1.1831.00
358_G387_A1.1801.00
584_M588_R1.1781.00
15_L18_S1.1771.00
502_I507_T1.1721.00
438_V442_L1.1721.00
121_F148_S1.1701.00
507_T511_P1.1691.00
32_I36_G1.1671.00
498_K501_H1.1651.00
177_L213_L1.1631.00
259_L341_A1.1621.00
182_F192_L1.1601.00
120_I147_S1.1601.00
506_F510_P1.1561.00
544_L547_L1.1531.00
375_G460_R1.1511.00
602_D606_R1.1441.00
27_L30_L1.1431.00
8_T11_L1.1421.00
533_L537_L1.1411.00
389_L456_C1.1401.00
347_N406_S1.1381.00
39_S122_I1.1351.00
196_S200_L1.1331.00
31_A35_S1.1321.00
185_M210_V1.1251.00
398_I539_L1.1231.00
84_M345_L1.1191.00
505_A508_N1.1171.00
482_A485_C1.1161.00
300_I450_M1.1161.00
274_W277_I1.1131.00
181_A210_V1.1101.00
235_H243_S1.1001.00
47_I90_L1.0981.00
507_T510_P1.0961.00
132_D193_D1.0941.00
484_L488_I1.0931.00
277_I281_A1.0911.00
362_I454_T1.0901.00
124_S147_S1.0871.00
292_L442_L1.0871.00
39_S45_I1.0861.00
500_M503_A1.0861.00
298_Q307_S1.0861.00
508_N511_P1.0821.00
77_M130_V1.0811.00
361_A384_T1.0811.00
42_G89_S1.0801.00
477_A480_L1.0791.00
100_L473_T1.0771.00
80_L342_L1.0771.00
536_L539_L1.0711.00
97_L476_V1.0701.00
578_P582_G1.0671.00
258_I319_V1.0671.00
364_S474_M1.0651.00
596_R601_L1.0651.00
179_M183_L1.0651.00
56_A60_L1.0651.00
37_I41_V1.0631.00
94_V477_A1.0621.00
39_S46_G1.0601.00
10_S45_I1.0591.00
547_L550_L1.0581.00
51_I54_L1.0581.00
235_H251_V1.0571.00
411_W538_L1.0571.00
505_A511_P1.0541.00
186_G192_L1.0541.00
278_L282_I1.0531.00
36_G93_V1.0531.00
40_L43_G1.0491.00
500_M506_F1.0481.00
417_L429_G1.0471.00
138_I179_M1.0461.00
497_P501_H1.0461.00
354_L478_M1.0451.00
387_A478_M1.0391.00
121_F125_M1.0381.00
591_F595_F1.0371.00
531_P535_L1.0360.99
288_L439_T1.0320.99
470_V475_I1.0300.99
541_M545_P1.0290.99
66_P69_E1.0210.99
17_A21_S1.0210.99
21_S35_S1.0210.99
618_A623_P1.0150.99
502_I505_A1.0130.99
548_Y551_W1.0120.99
208_S269_T1.0120.99
649_S654_L1.0110.99
409_Y412_Q1.0100.99
314_I436_L1.0040.99
361_A469_E1.0030.99
642_K645_Q1.0030.99
42_G46_G0.9990.99
39_S51_I0.9980.99
44_V51_I0.9960.99
13_L38_T0.9940.99
507_T512_A0.9920.99
539_L542_P0.9920.99
501_H504_H0.9860.99
616_A619_Q0.9850.99
188_E206_L0.9850.99
121_F250_M0.9840.99
43_G49_S0.9780.99
535_L546_G0.9770.99
593_A597_L0.9750.99
609_K616_A0.9750.99
578_P581_N0.9750.99
91_L353_G0.9740.99
651_D654_L0.9730.99
378_A382_P0.9700.99
612_A615_T0.9700.99
582_G585_Q0.9700.99
402_N485_C0.9680.99
497_P500_M0.9670.99
469_E475_I0.9620.99
613_H616_A0.9580.99
42_G49_S0.9570.99
504_H507_T0.9560.99
17_A119_N0.9540.99
11_L18_S0.9530.99
494_W497_P0.9530.99
39_S49_S0.9520.99
594_L597_L0.9490.99
639_R643_E0.9470.99
595_F598_R0.9460.99
87_V345_L0.9440.99
610_G615_T0.9440.99
504_H511_P0.9410.99
36_G100_L0.9410.99
527_T532_S0.9380.99
392_C396_S0.9380.99
531_P534_L0.9380.99
311_N344_H0.9380.99
96_S118_M0.9370.99
638_Q642_K0.9370.99
212_L275_W0.9370.99
291_V307_S0.9360.99
138_I182_F0.9340.99
317_L432_A0.9330.99
276_G280_M0.9320.99
625_W629_V0.9290.99
476_V480_L0.9250.99
385_A389_L0.9250.99
381_M469_E0.9250.99
140_L143_M0.9240.99
186_G189_S0.9210.99
116_F150_F0.9200.99
630_I633_I0.9190.99
470_V474_M0.9180.99
275_W279_V0.9180.99
364_S470_V0.9170.99
208_S275_W0.9150.99
52_T58_V0.9140.99
133_N136_W0.9120.99
111_A115_G0.9110.99
599_Q603_P0.9090.99
41_V44_V0.9090.99
590_V600_Q0.9050.99
10_S49_S0.9040.99
47_I51_I0.9030.99
337_G413_S0.9010.99
389_L392_C0.9000.99
593_A599_Q0.8990.99
643_E647_L0.8980.99
224_M316_L0.8980.99
310_E443_A0.8970.99
18_S116_F0.8970.99
107_E110_G0.8970.99
207_A269_T0.8940.99
27_L31_A0.8880.98
661_A665_V0.8870.98
588_R595_F0.8870.98
580_G583_V0.8870.98
634_V638_Q0.8860.98
207_A211_F0.8830.98
611_L615_T0.8820.98
209_A212_L0.8790.98
208_S212_L0.8780.98
11_L75_L0.8700.98
289_L293_Y0.8690.98
114_M241_H0.8680.98
501_H507_T0.8680.98
534_L538_L0.8660.98
600_Q603_P0.8630.98
551_W554_S0.8620.98
13_L41_V0.8620.98
576_M580_G0.8600.98
148_S250_M0.8600.98
280_M317_L0.8530.98
598_R601_L0.8520.98
576_M579_S0.8500.98
589_V596_R0.8500.98
15_L22_L0.8490.98
627_E631_R0.8490.98
452_G546_G0.8480.98
472_N479_L0.8470.98
537_L541_M0.8460.98
641_A645_Q0.8430.98
81_S260_K0.8430.98
284_A432_A0.8430.98
363_I374_M0.8410.98
595_F599_Q0.8410.98
311_N446_C0.8410.98
184_L188_E0.8400.98
183_L187_R0.8390.98
209_A213_L0.8370.98
378_A456_C0.8350.98
297_E302_R0.8330.98
589_V593_A0.8330.98
611_L617_R0.8320.98
509_T512_A0.8300.98
300_I374_M0.8290.98
121_F251_V0.8270.98
597_L601_L0.8260.98
622_E626_D0.8260.98
631_R634_V0.8240.97
10_S14_Y0.8220.97
388_C451_Y0.8190.97
189_S200_L0.8190.97
35_S39_S0.8160.97
178_I257_G0.8160.97
76_R132_D0.8160.97
621_T625_W0.8140.97
94_V353_G0.8120.97
21_S25_L0.8110.97
28_D36_G0.8110.97
28_D32_I0.8100.97
549_W553_R0.8090.97
461_S464_A0.8080.97
49_S53_Q0.8070.97
9_W13_L0.8070.97
36_G39_S0.8050.97
269_T275_W0.8030.97
480_L484_L0.8020.97
400_P490_L0.8020.97
538_L546_G0.8000.97
600_Q605_L0.8000.97
42_G45_I0.8000.97
184_L206_L0.7990.97
527_T531_P0.7980.97
508_N512_A0.7980.97
593_A598_R0.7950.97
461_S467_A0.7940.97
13_L45_I0.7940.97
77_M82_A0.7930.97
504_H508_N0.7930.97
163_A236_P0.7920.97
30_L35_S0.7910.97
504_H509_T0.7910.97
380_R459_P0.7910.97
101_T474_M0.7870.97
49_S52_T0.7860.97
231_L243_S0.7860.97
95_C122_I0.7840.97
624_F627_E0.7820.97
222_A249_V0.7820.97
408_W412_Q0.7810.97
50_G53_Q0.7800.96
444_V543_L0.7800.96
640_L644_I0.7800.96
204_P207_A0.7790.96
102_Y240_S0.7780.96
441_G541_M0.7760.96
636_A640_L0.7740.96
267_A338_L0.7740.96
539_L549_W0.7740.96
498_K506_F0.7740.96
16_F20_A0.7730.96
174_G227_L0.7720.96
635_S639_R0.7700.96
303_L449_K0.7700.96
550_L554_S0.7690.96
579_S584_M0.7680.96
282_I285_I0.7640.96
500_M507_T0.7630.96
210_V214_A0.7600.96
579_S582_G0.7600.96
545_P548_Y0.7590.96
575_A578_P0.7590.96
76_R195_A0.7590.96
92_V95_C0.7570.96
537_L542_P0.7570.96
56_A59_T0.7550.96
620_S624_F0.7550.96
506_F511_P0.7550.96
503_A511_P0.7530.96
280_M436_L0.7510.96
501_H505_A0.7510.96
526_H532_S0.7460.95
102_Y369_H0.7460.95
125_M222_A0.7460.95
537_L544_L0.7450.95
498_K502_I0.7440.95
575_A580_G0.7430.95
235_H308_T0.7420.95
504_H510_P0.7400.95
542_P547_L0.7400.95
65_A68_F0.7400.95
402_N488_I0.7380.95
388_C392_C0.7380.95
578_P583_V0.7370.95
46_G50_G0.7360.95
362_I455_F0.7320.95
31_A34_L0.7290.95
476_V479_L0.7290.95
647_L658_Y0.7290.95
447_F450_M0.7280.95
30_L34_L0.7280.95
243_S301_K0.7280.95
261_V264_D0.7270.95
384_T470_V0.7270.95
638_Q664_V0.7270.95
503_A506_F0.7250.95
46_G49_S0.7240.95
174_G220_A0.7230.95
274_W278_L0.7210.95
491_S494_W0.7200.95
40_L46_G0.7200.95
285_I289_L0.7190.94
612_A616_A0.7180.94
584_M591_F0.7150.94
584_M592_S0.7140.94
269_T274_W0.7140.94
321_V337_G0.7140.94
11_L14_Y0.7130.94
528_Q531_P0.7130.94
280_M321_V0.7120.94
542_P554_S0.7120.94
284_A317_L0.7110.94
133_N193_D0.7110.94
197_F261_V0.7100.94
283_G313_G0.7100.94
457_G460_R0.7090.94
442_L445_M0.7080.94
215_F278_L0.7080.94
533_L540_A0.7070.94
654_L657_L0.7050.94
609_K615_T0.7040.94
365_R470_V0.7040.94
41_V45_I0.7020.94
383_W387_A0.7010.94
619_Q623_P0.7000.94
185_M189_S0.6990.94
577_A582_G0.6980.94
575_A579_S0.6960.93
624_F628_R0.6940.93
82_A86_L0.6940.93
121_F171_A0.6930.93
577_A580_G0.6930.93
584_M587_L0.6930.93
539_L543_L0.6920.93
14_Y21_S0.6920.93
537_L552_C0.6910.93
581_N585_Q0.6910.93
525_F528_Q0.6900.93
343_F405_I0.6900.93
314_I440_G0.6890.93
452_G456_C0.6890.93
47_I86_L0.6880.93
232_P306_W0.6880.93
134_A194_F0.6870.93
40_L51_I0.6850.93
255_I279_V0.6850.93
53_Q56_A0.6840.93
118_M242_A0.6830.93
528_Q532_S0.6830.93
43_G86_L0.6800.93
588_R596_R0.6790.93
95_C118_M0.6790.93
532_S542_P0.6790.93
28_D105_E0.6770.93
382_P385_A0.6770.93
214_A261_V0.6760.92
225_M290_G0.6760.92
137_F178_I0.6740.92
400_P404_F0.6740.92
580_G588_R0.6720.92
399_P536_L0.6720.92
492_A495_L0.6720.92
133_N192_L0.6710.92
459_P464_A0.6690.92
110_G156_Q0.6690.92
439_T442_L0.6690.92
529_V532_S0.6680.92
540_A546_G0.6670.92
390_I485_C0.6650.92
94_V480_L0.6650.92
36_G40_L0.6640.92
45_I48_I0.6640.92
592_S595_F0.6640.92
32_I100_L0.6640.92
231_L234_A0.6610.92
546_G549_W0.6600.92
646_H649_S0.6580.91
43_G50_G0.6560.91
614_V617_R0.6560.91
293_Y306_W0.6550.91
280_M320_G0.6550.91
505_A512_A0.6540.91
441_G545_P0.6540.91
639_R646_H0.6530.91
89_S93_V0.6530.91
361_A365_R0.6510.91
402_N406_S0.6510.91
499_I507_T0.6500.91
14_Y17_A0.6500.91
543_L546_G0.6500.91
378_A389_L0.6490.91
311_N314_I0.6490.91
474_M478_M0.6490.91
64_F69_E0.6470.91
43_G52_T0.6470.91
310_E446_C0.6470.91
343_F347_N0.6440.91
381_M467_A0.6440.91
224_M235_H0.6430.91
550_L553_R0.6430.91
643_E646_H0.6420.90
378_A386_A0.6400.90
279_V319_V0.6390.90
288_L292_L0.6380.90
303_L453_I0.6370.90
90_L95_C0.6370.90
98_Y357_L0.6360.90
12_I16_F0.6360.90
231_L235_H0.6360.90
74_T133_N0.6350.90
435_M439_T0.6340.90
532_S550_L0.6330.90
117_F150_F0.6320.90
621_T624_F0.6310.90
346_L492_A0.6310.90
623_P626_D0.6290.90
350_L402_N0.6280.89
630_I634_V0.6280.89
219_G278_L0.6270.89
344_H347_N0.6270.89
459_P467_A0.6270.89
208_S278_L0.6260.89
610_G618_A0.6260.89
537_L549_W0.6260.89
49_S82_A0.6260.89
581_N584_M0.6260.89
52_T57_G0.6250.89
236_P302_R0.6250.89
598_R602_D0.6250.89
300_I363_I0.6240.89
218_F257_G0.6240.89
644_I665_V0.6240.89
300_I454_T0.6220.89
97_L477_A0.6220.89
315_I345_L0.6210.89
351_F446_C0.6210.89
128_L253_I0.6210.89
386_A390_I0.6200.89
125_M129_L0.6190.89
350_L484_L0.6170.89
117_F147_S0.6170.89
67_P70_F0.6160.89
14_Y22_L0.6150.88
380_R461_S0.6150.88
81_S85_V0.6140.88
583_V586_P0.6130.88
392_C395_I0.6130.88
222_A253_I0.6110.88
302_R354_L0.6100.88
228_H306_W0.6100.88
652_F656_C0.6090.88
287_A317_L0.6070.88
202_L207_A0.6060.88
161_I164_G0.6060.88
472_N475_I0.6060.88
353_G481_L0.6060.88
549_W554_S0.6050.88
134_A185_M0.6050.88
13_L21_S0.6050.88
664_V668_I0.6040.88
540_A547_L0.6030.88
215_F219_G0.6030.88
35_S38_T0.6030.88
584_M596_R0.6030.88
24_L30_L0.6010.87
386_A389_L0.6010.87
527_T533_L0.6000.87
178_I217_G0.6000.87
531_P536_L0.5990.87
642_K661_A0.5990.87
172_H175_S0.5980.87
616_A620_S0.5970.87
539_L546_G0.5970.87
80_L259_L0.5960.87
348_H352_K0.5960.87
622_E627_E0.5950.87
50_G82_A0.5940.87
577_A584_M0.5940.87
124_S127_A0.5930.87
492_A496_A0.5930.87
41_V58_V0.5920.87
119_N123_A0.5920.87
36_G43_G0.5920.87
25_L31_A0.5920.87
222_A235_H0.5920.87
594_L601_L0.5900.86
281_A435_M0.5900.86
28_D31_A0.5900.86
374_M377_L0.5890.86
90_L94_V0.5880.86
27_L32_I0.5870.86
81_S130_V0.5870.86
532_S539_L0.5860.86
57_G60_L0.5860.86
64_F67_P0.5850.86
190_G193_D0.5850.86
628_R631_R0.5840.86
613_H618_A0.5840.86
578_P584_M0.5830.86
544_L552_C0.5820.86
634_V637_T0.5810.86
499_I505_A0.5800.85
443_A446_C0.5800.85
32_I40_L0.5800.85
580_G595_F0.5800.85
150_F164_G0.5800.85
537_L548_Y0.5790.85
36_G49_S0.5780.85
648_Q653_R0.5780.85
194_F197_F0.5780.85
102_Y125_M0.5780.85
379_K459_P0.5770.85
535_L538_L0.5760.85
127_A139_V0.5760.85
255_I319_V0.5750.85
577_A583_V0.5740.85
125_M148_S0.5740.85
498_K507_T0.5720.85
243_S308_T0.5710.85
51_I55_H0.5710.85
201_S204_P0.5710.85
96_S119_N0.5700.84
535_L544_L0.5690.84
75_L130_V0.5680.84
281_A431_I0.5680.84
86_L90_L0.5670.84
121_F235_H0.5670.84
534_L541_M0.5660.84
82_A85_V0.5660.84
590_V593_A0.5650.84
576_M583_V0.5640.84
11_L123_A0.5640.84
191_S200_L0.5630.84
31_A112_A0.5620.84
314_I439_T0.5620.84
78_D256_F0.5620.84
620_S629_V0.5620.84
102_Y121_F0.5610.84
52_T55_H0.5610.84
40_L49_S0.5610.84
308_T312_V0.5610.84
32_I35_S0.5610.84
596_R603_P0.5600.83
499_I503_A0.5600.83
270_G276_G0.5590.83
243_S251_V0.5580.83
530_T533_L0.5570.83
587_L591_F0.5570.83
287_A314_I0.5570.83
125_M249_V0.5560.83
446_C449_K0.5550.83
626_D631_R0.5550.83
401_L486_V0.5540.83
54_L57_G0.5540.83
547_L552_C0.5540.83
33_K36_G0.5500.82
586_P590_V0.5490.82
51_I56_A0.5490.82
575_A583_V0.5480.82
10_S18_S0.5480.82
542_P550_L0.5480.82
648_Q655_Y0.5470.82
261_V265_L0.5460.82
362_I377_L0.5460.82
148_S446_C0.5460.82
546_G553_R0.5460.82
235_H248_G0.5440.82
583_V596_R0.5440.82
500_M505_A0.5430.82
665_V669_A0.5430.82
528_Q534_L0.5420.81
49_S54_L0.5420.81
644_I647_L0.5410.81
105_E367_H0.5400.81
576_M591_F0.5400.81
589_V592_S0.5400.81
440_G538_L0.5380.81
33_K40_L0.5380.81
310_E407_E0.5370.81
581_N592_S0.5370.81
396_S543_L0.5360.81
384_T467_A0.5360.81
207_A266_L0.5340.80
576_M584_M0.5340.80
411_W534_L0.5340.80
344_H402_N0.5330.80
660_V664_V0.5320.80
62_A73_L0.5310.80
642_K646_H0.5310.80
380_R464_A0.5300.80
651_D656_C0.5300.80
251_V254_G0.5300.80
372_E453_I0.5300.80
578_P586_P0.5290.80
91_L349_A0.5290.80
231_L251_V0.5270.80
541_M548_Y0.5270.80
634_V644_I0.5270.80
102_Y243_S0.5260.79
381_M470_V0.5250.79
29_R33_K0.5250.79
530_T537_L0.5230.79
297_E306_W0.5220.79
595_F601_L0.5220.79
547_L554_S0.5210.79
582_G586_P0.5210.79
645_Q650_G0.5200.79
55_H59_T0.5190.79
467_A470_V0.5180.78
27_L35_S0.5170.78
499_I502_I0.5170.78
591_F594_L0.5170.78
590_V598_R0.5160.78
352_K356_F0.5160.78
219_G227_L0.5160.78
461_S465_E0.5160.78
340_G409_Y0.5160.78
35_S119_N0.5150.78
525_F530_T0.5150.78
384_T475_I0.5130.78
338_L342_L0.5130.78
632_P637_T0.5130.78
95_C357_L0.5120.78
539_L548_Y0.5110.77
102_Y301_K0.5110.77
581_N588_R0.5100.77
121_F151_L0.5100.77
620_S623_P0.5090.77
300_I359_A0.5090.77
196_S199_T0.5090.77
475_I478_M0.5090.77
92_V169_F0.5080.77
545_P551_W0.5070.77
25_L112_A0.5070.77
635_S642_K0.5070.77
310_E351_F0.5060.77
134_A265_L0.5060.77
167_Y235_H0.5060.77
545_P553_R0.5060.77
13_L18_S0.5050.77
542_P549_W0.5040.77
307_S449_K0.5040.77
374_M454_T0.5030.76
586_P597_L0.5030.76
248_G308_T0.5020.76
300_I362_I0.5020.76
170_I223_G0.5020.76
622_E625_W0.5020.76
656_C663_L0.5010.76
96_S122_I0.5010.76
620_S625_W0.5010.76
577_A581_N0.5000.76
152_V167_Y0.5000.76
24_L27_L0.5000.76
50_G55_H0.5000.76
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3rkoL 1 0.8854 100 0.292 Contact Map
4he8L 1 0.8839 100 0.297 Contact Map
3rkoM 1 0.7158 100 0.387 Contact Map
4he8M 1 0.686 100 0.417 Contact Map
3rkoN 1 0.683 100 0.436 Contact Map
4he8N 1 0.6324 100 0.479 Contact Map
4he8K 1 0.1369 51.1 0.975 Contact Map
3rkoK 1 0.1429 45.9 0.976 Contact Map
3bz1X 1 0.0536 3.1 0.986 Contact Map
2mofA 1 0.0536 2.5 0.987 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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