SYD - ECOLI - GREMLIN Contacts

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SYD - Aspartate--tRNA ligase

UniProt:	P21889	Sequences: MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRADALKLASELRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTIINRADVLPLDSNHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAERRYGSDKPDLRNPMELTDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGASLTRKQIDEYGNFVKIYGAKGLAYIKVNERAKGLEGINSPVAKFLNAEIIEDILDRTAAQDGDMIFFGADNKKIVADAMGALRLKVGKDLGLTDESKWAPLWVIDFPMFEDDGEGGLTAMHHPFTSPKDMTAAELKAAPENAVANAYDMVINGYEVGGGSVRIHNGDMQQTVFGILGINEEEQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTEAPSFANPTALAELSIQVVKKAENN	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10097
Length:	590 (573)
Sequences:	3300 (1639)
Seq/√Len:	68.5

ECOLI - SYD
BACSU - SYDND

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
13_H	16_Q	5.191	1.00
278_R	291_E	5.021	1.00
151_F	250_A	4.238	1.00
47_V	96_A	3.979	1.00
488_V	529_A	3.974	1.00
11_L	91_E	3.938	1.00
324_P	387_Q	3.880	1.00
148_V	232_I	3.793	1.00
297_D	383_R	3.672	1.00
146_S	150_R	3.609	1.00
286_L	426_A	3.500	1.00
17_Q	72_T	3.300	1.00
106_D	522_K	3.148	1.00
257_L	263_D	3.123	1.00
412_K	416_D	3.085	1.00
70_Q	100_T	3.015	1.00
72_T	98_S	2.905	1.00
145_T	535_L	2.797	1.00
465_A	468_N	2.795	1.00
252_V	476_M	2.789	1.00
164_M	213_V	2.764	1.00
421_D	424_K	2.730	1.00
511_R	519_D	2.687	1.00
155_H	250_A	2.677	1.00
63_L	69_I	2.642	1.00
10_R	13_H	2.638	1.00
140_T	543_T	2.625	1.00
241_A	472_N	2.571	1.00
164_M	216_F	2.513	1.00
160_I	206_F	2.453	1.00
573_P	577_A	2.450	1.00
432_D	455_K	2.413	1.00
176_Y	560_A	2.393	1.00
20_L	94_V	2.361	1.00
461_E	468_N	2.315	1.00
77_A	83_I	2.307	1.00
463_K	498_T	2.273	1.00
19_T	72_T	2.250	1.00
320_A	384_T	2.245	1.00
242_P	269_V	2.243	1.00
17_Q	97_S	2.193	1.00
444_L	467_E	2.176	1.00
273_A	470_V	2.165	1.00
147_L	258_E	2.130	1.00
10_R	88_A	2.118	1.00
271_T	274_E	2.099	1.00
176_Y	182_V	2.064	1.00
20_L	45_V	2.062	1.00
268_P	426_A	2.051	1.00
507_E	511_R	2.046	1.00
279_Y	291_E	2.042	1.00
488_V	491_H	2.028	1.00
236_T	239_M	2.027	1.00
83_I	91_E	2.000	1.00
274_E	278_R	1.999	1.00
286_L	428_L	1.959	1.00
144_I	539_T	1.957	1.00
14_V	77_A	1.954	1.00
357_R	388_D	1.952	1.00
273_A	277_R	1.939	1.00
438_D	441_E	1.934	1.00
320_A	392_I	1.931	1.00
339_N	342_K	1.927	1.00
146_S	153_D	1.911	1.00
239_M	244_V	1.905	1.00
271_T	432_D	1.888	1.00
331_R	335_D	1.888	1.00
17_Q	74_T	1.878	1.00
281_S	407_G	1.877	1.00
497_Q	507_E	1.866	1.00
186_K	570_F	1.861	1.00
142_A	153_D	1.853	1.00
76_R	95_L	1.842	1.00
288_N	411_L	1.804	1.00
248_M	533_F	1.801	1.00
21_C	70_Q	1.798	1.00
153_D	210_Y	1.794	1.00
356_E	388_D	1.770	1.00
47_V	71_V	1.766	1.00
139_K	158_L	1.766	1.00
5_Y	42_E	1.763	1.00
456_D	472_N	1.757	1.00
234_V	531_L	1.756	1.00
184_K	580_S	1.747	1.00
42_E	45_V	1.747	1.00
562_C	565_T	1.746	1.00
270_M	428_L	1.741	1.00
177_L	571_A	1.740	1.00
373_N	376_I	1.732	1.00
254_H	258_E	1.728	1.00
138_L	206_F	1.727	1.00
9_L	92_I	1.711	1.00
74_T	97_S	1.708	1.00
196_L	516_F	1.705	1.00
11_L	14_V	1.700	1.00
501_G	507_E	1.698	1.00
427_P	478_I	1.693	1.00
298_L	383_R	1.691	1.00
438_D	445_T	1.691	1.00
244_V	529_A	1.689	1.00
335_D	338_G	1.684	1.00
545_T	550_D	1.679	0.99
292_L	319_A	1.671	0.99
253_R	265_G	1.661	0.99
506_N	509_E	1.661	0.99
137_R	545_T	1.653	0.99
45_V	94_V	1.649	0.99
147_L	254_H	1.647	0.99
9_L	13_H	1.646	0.99
577_A	584_V	1.632	0.99
323_V	326_G	1.631	0.99
32_S	51_P	1.626	0.99
159_D	210_Y	1.626	0.99
75_V	94_V	1.599	0.99
505_I	513_K	1.597	0.99
154_D	254_H	1.597	0.99
458_T	470_V	1.592	0.99
505_I	510_Q	1.584	0.99
277_R	294_D	1.583	0.99
151_F	155_H	1.579	0.99
152_M	234_V	1.577	0.99
483_V	538_L	1.565	0.99
341_V	409_L	1.550	0.99
232_I	535_L	1.547	0.99
455_K	470_V	1.540	0.99
463_K	501_G	1.537	0.99
270_M	430_V	1.536	0.99
5_Y	45_V	1.534	0.99
478_I	483_V	1.533	0.99
150_R	153_D	1.510	0.99
295_V	380_I	1.507	0.99
42_E	207_D	1.500	0.99
239_M	243_Q	1.498	0.99
256_W	425_W	1.496	0.99
256_W	542_L	1.488	0.99
303_E	308_A	1.487	0.99
240_T	243_Q	1.481	0.99
353_K	365_N	1.475	0.99
24_V	69_I	1.473	0.99
437_E	447_M	1.468	0.99
103_N	525_T	1.465	0.99
378_E	382_D	1.463	0.99
9_L	18_V	1.454	0.99
129_L	204_S	1.447	0.98
275_A	281_S	1.444	0.98
20_L	38_M	1.442	0.98
75_V	92_I	1.417	0.98
148_V	535_L	1.414	0.98
145_T	232_I	1.413	0.98
510_Q	518_L	1.402	0.98
379_D	382_D	1.400	0.98
493_G	522_K	1.392	0.98
59_L	99_L	1.383	0.98
139_K	143_K	1.381	0.98
18_V	94_V	1.378	0.98
295_V	299_L	1.378	0.98
323_V	417_L	1.376	0.98
435_M	499_V	1.367	0.98
15_G	74_T	1.354	0.98
481_Y	547_N	1.353	0.98
239_M	488_V	1.338	0.97
399_K	403_A	1.336	0.97
267_F	427_P	1.335	0.97
234_V	248_M	1.316	0.97
341_V	405_A	1.315	0.97
441_E	445_T	1.310	0.97
245_R	269_V	1.306	0.97
260_K	542_L	1.301	0.97
241_A	245_R	1.301	0.97
9_L	45_V	1.300	0.97
70_Q	102_I	1.300	0.97
169_T	516_F	1.292	0.97
317_R	403_A	1.290	0.97
182_V	560_A	1.288	0.97
476_M	533_F	1.287	0.97
319_A	403_A	1.282	0.97
166_T	197_F	1.275	0.97
462_L	469_A	1.267	0.96
493_G	497_Q	1.266	0.96
2_R	207_D	1.251	0.96
423_S	544_G	1.250	0.96
144_I	259_V	1.245	0.96
148_V	251_L	1.236	0.96
301_S	308_A	1.231	0.96
135_A	206_F	1.225	0.96
144_I	535_L	1.220	0.96
164_M	214_K	1.217	0.95
5_Y	207_D	1.214	0.95
242_P	245_R	1.213	0.95
168_A	571_A	1.208	0.95
267_F	428_L	1.207	0.95
453_S	495_M	1.207	0.95
239_M	529_A	1.205	0.95
80_E	83_I	1.203	0.95
150_R	154_D	1.202	0.95
143_K	146_S	1.200	0.95
167_K	569_S	1.195	0.95
56_A	99_L	1.191	0.95
374_A	378_E	1.184	0.95
144_I	255_L	1.175	0.95
11_L	77_A	1.165	0.94
317_R	399_K	1.161	0.94
270_M	275_A	1.155	0.94
332_K	336_E	1.154	0.94
295_V	320_A	1.152	0.94
240_T	472_N	1.150	0.94
27_R	64_R	1.150	0.94
36_I	49_F	1.147	0.94
304_F	307_F	1.145	0.94
160_I	201_L	1.144	0.94
133_E	545_T	1.142	0.94
137_R	543_T	1.141	0.94
376_I	379_D	1.140	0.94
458_T	461_E	1.134	0.93
350_A	394_F	1.133	0.93
386_A	392_I	1.131	0.93
542_L	547_N	1.127	0.93
196_L	565_T	1.126	0.93
96_A	99_L	1.125	0.93
297_D	300_K	1.122	0.93
305_A	309_G	1.122	0.93
492_N	495_M	1.121	0.93
135_A	139_K	1.120	0.93
509_E	513_K	1.111	0.93
299_L	302_V	1.107	0.93
299_L	318_V	1.103	0.92
77_A	91_E	1.101	0.92
242_P	246_E	1.101	0.92
4_E	13_H	1.100	0.92
147_L	259_V	1.099	0.92
155_H	247_V	1.098	0.92
322_R	392_I	1.096	0.92
439_D	443_G	1.093	0.92
57_L	61_S	1.090	0.92
79_D	82_N	1.090	0.92
461_E	464_A	1.084	0.92
459_A	463_K	1.083	0.92
253_R	266_D	1.078	0.92
438_D	443_G	1.074	0.91
288_N	414_G	1.071	0.91
144_I	542_L	1.070	0.91
459_A	495_M	1.068	0.91
132_P	136_Q	1.068	0.91
4_E	16_Q	1.067	0.91
152_M	251_L	1.065	0.91
277_R	319_A	1.064	0.91
166_T	564_M	1.063	0.91
4_E	9_L	1.062	0.91
147_L	255_L	1.054	0.91
400_K	404_D	1.051	0.91
473_A	485_G	1.050	0.90
183_H	560_A	1.048	0.90
39_R	66_E	1.045	0.90
50_D	76_R	1.044	0.90
571_A	576_L	1.043	0.90
355_N	365_N	1.042	0.90
374_A	377_I	1.039	0.90
322_R	387_Q	1.038	0.90
168_A	575_A	1.038	0.90
580_S	583_V	1.034	0.90
8_Q	13_H	1.030	0.90
295_V	394_F	1.030	0.90
344_Y	408_A	1.030	0.90
255_L	259_V	1.030	0.90
166_T	565_T	1.029	0.90
129_L	206_F	1.024	0.89
45_V	75_V	1.024	0.89
302_V	376_I	1.024	0.89
85_R	91_E	1.022	0.89
336_E	339_N	1.022	0.89
354_V	386_A	1.020	0.89
203_M	521_L	1.018	0.89
333_Q	416_D	1.018	0.89
397_D	401_I	1.017	0.89
286_L	424_K	1.015	0.89
261_G	264_L	1.015	0.89
412_K	415_K	1.008	0.89
149_R	159_D	1.004	0.88
8_Q	42_E	1.004	0.88
453_S	472_N	1.002	0.88
398_N	401_I	1.001	0.88
384_T	392_I	1.000	0.88
246_E	250_A	1.000	0.88
58_K	61_S	0.999	0.88
201_L	553_A	0.999	0.88
438_D	442_G	0.997	0.88
557_T	561_A	0.996	0.88
156_G	208_R	0.996	0.88
290_M	323_V	0.994	0.88
150_R	258_E	0.994	0.88
147_L	150_R	0.994	0.88
71_V	96_A	0.993	0.88
573_P	584_V	0.990	0.88
340_F	412_K	0.986	0.87
432_D	470_V	0.984	0.87
236_T	244_V	0.982	0.87
449_H	487_S	0.979	0.87
115_V	133_E	0.974	0.87
62_E	104_R	0.973	0.87
574_T	578_E	0.971	0.87
329_L	417_L	0.970	0.87
121_R	128_D	0.970	0.87
10_R	91_E	0.969	0.87
498_T	501_G	0.965	0.86
49_F	96_A	0.961	0.86
446_A	499_V	0.961	0.86
347_K	397_D	0.960	0.86
344_Y	405_A	0.959	0.86
133_E	137_R	0.956	0.86
203_M	525_T	0.953	0.86
74_T	95_L	0.952	0.86
322_R	384_T	0.950	0.85
381_L	386_A	0.950	0.85
244_V	488_V	0.947	0.85
455_K	472_N	0.946	0.85
364_I	381_L	0.944	0.85
49_F	99_L	0.943	0.85
539_T	543_T	0.940	0.85
60_A	99_L	0.936	0.85
464_A	468_N	0.933	0.84
352_I	369_A	0.932	0.84
7_G	10_R	0.932	0.84
197_F	565_T	0.927	0.84
301_S	376_I	0.927	0.84
151_F	251_L	0.925	0.84
126_Y	564_M	0.920	0.84
274_E	277_R	0.919	0.83
197_F	562_C	0.916	0.83
27_R	34_I	0.915	0.83
484_G	533_F	0.912	0.83
64_R	67_F	0.911	0.83
354_V	392_I	0.909	0.83
557_T	563_L	0.909	0.83
182_V	188_Y	0.908	0.83
340_F	344_Y	0.907	0.83
302_V	308_A	0.906	0.83
148_V	255_L	0.906	0.83
466_P	469_A	0.905	0.83
415_K	422_E	0.903	0.82
5_Y	8_Q	0.903	0.82
145_T	212_I	0.902	0.82
545_T	548_I	0.901	0.82
310_P	316_G	0.899	0.82
146_S	210_Y	0.897	0.82
6_C	207_D	0.895	0.82
155_H	208_R	0.893	0.82
140_T	259_V	0.892	0.82
289_P	321_L	0.891	0.82
420_T	424_K	0.890	0.81
358_A	388_D	0.889	0.81
143_K	153_D	0.889	0.81
9_L	91_E	0.885	0.81
547_N	550_D	0.885	0.81
457_M	460_A	0.884	0.81
447_M	471_A	0.882	0.81
268_P	271_T	0.880	0.81
140_T	144_I	0.880	0.81
8_Q	45_V	0.880	0.81
160_I	204_S	0.879	0.81
572_N	575_A	0.879	0.81
433_F	447_M	0.878	0.81
293_T	384_T	0.878	0.81
252_V	533_F	0.877	0.81
511_R	522_K	0.877	0.81
260_K	264_L	0.877	0.81
460_A	463_K	0.875	0.80
38_M	69_I	0.875	0.80
373_N	377_I	0.874	0.80
112_S	127_L	0.874	0.80
244_V	247_V	0.873	0.80
248_M	531_L	0.868	0.80
352_I	366_S	0.866	0.80
161_E	214_K	0.865	0.80
338_G	342_K	0.863	0.79
138_L	160_I	0.862	0.79
203_M	517_L	0.862	0.79
152_M	210_Y	0.862	0.79
278_R	292_L	0.861	0.79
41_R	139_K	0.861	0.79
59_L	62_E	0.861	0.79
268_P	286_L	0.858	0.79
411_L	414_G	0.858	0.79
142_A	146_S	0.858	0.79
258_E	261_G	0.857	0.79
260_K	263_D	0.857	0.79
25_N	113_N	0.856	0.79
29_D	32_S	0.855	0.79
5_Y	9_L	0.855	0.79
317_R	402_V	0.855	0.79
293_T	322_R	0.853	0.79
257_L	261_G	0.851	0.79
266_D	269_V	0.850	0.78
123_K	566_E	0.850	0.78
236_T	243_Q	0.850	0.78
455_K	458_T	0.850	0.78
395_G	406_M	0.849	0.78
435_M	446_A	0.848	0.78
459_A	462_L	0.847	0.78
58_K	62_E	0.846	0.78
145_T	159_D	0.845	0.78
490_I	499_V	0.844	0.78
481_Y	541_L	0.844	0.78
346_A	349_L	0.842	0.78
49_F	60_A	0.840	0.78
322_R	385_A	0.838	0.77
457_M	461_E	0.838	0.77
104_R	494_D	0.837	0.77
421_D	426_A	0.833	0.77
36_I	63_L	0.828	0.77
271_T	431_I	0.826	0.76
67_F	101_I	0.825	0.76
299_L	380_I	0.824	0.76
354_V	364_I	0.824	0.76
25_N	44_I	0.823	0.76
461_E	466_P	0.819	0.76
322_R	386_A	0.819	0.76
9_L	20_L	0.818	0.76
382_D	385_A	0.813	0.75
245_R	485_G	0.810	0.75
274_E	291_E	0.810	0.75
355_N	358_A	0.809	0.75
354_V	381_L	0.809	0.75
113_N	116_N	0.808	0.75
431_I	455_K	0.805	0.75
186_K	561_A	0.804	0.74
38_M	47_V	0.804	0.74
375_E	378_E	0.803	0.74
71_V	94_V	0.803	0.74
168_A	189_A	0.803	0.74
30_L	33_L	0.803	0.74
3_T	19_T	0.800	0.74
418_G	422_E	0.799	0.74
481_Y	540_M	0.796	0.74
299_L	376_I	0.795	0.74
510_Q	517_L	0.790	0.73
413_V	417_L	0.789	0.73
241_A	455_K	0.789	0.73
349_L	393_F	0.787	0.73
323_V	329_L	0.787	0.73
10_R	45_V	0.785	0.73
283_K	407_G	0.782	0.72
293_T	383_R	0.781	0.72
292_L	403_A	0.780	0.72
457_M	470_V	0.779	0.72
111_D	116_N	0.779	0.72
21_C	100_T	0.775	0.72
415_K	420_T	0.774	0.72
411_L	415_K	0.772	0.71
13_H	45_V	0.771	0.71
175_D	191_P	0.770	0.71
117_T	120_A	0.770	0.71
50_D	95_L	0.769	0.71
133_E	550_D	0.768	0.71
249_E	267_F	0.766	0.71
436_F	499_V	0.765	0.71
135_A	160_I	0.764	0.71
326_G	329_L	0.764	0.71
577_A	582_Q	0.762	0.70
166_T	562_C	0.762	0.70
319_A	406_M	0.761	0.70
183_H	580_S	0.759	0.70
150_R	254_H	0.757	0.70
13_H	89_T	0.755	0.70
224_D	481_Y	0.754	0.70
277_R	403_A	0.751	0.69
461_E	469_A	0.751	0.69
252_V	538_L	0.750	0.69
42_E	156_G	0.749	0.69
49_F	63_L	0.748	0.69
30_L	558_T	0.746	0.69
462_L	466_P	0.746	0.69
37_D	87_M	0.746	0.69
277_R	399_K	0.746	0.69
248_M	476_M	0.745	0.69
9_L	94_V	0.745	0.69
158_L	206_F	0.744	0.69
395_G	402_V	0.743	0.68
375_E	379_D	0.742	0.68
305_A	308_A	0.741	0.68
485_G	532_A	0.740	0.68
49_F	53_R	0.739	0.68
330_T	333_Q	0.738	0.68
436_F	502_I	0.737	0.68
200_L	564_M	0.735	0.68
441_E	574_T	0.735	0.68
580_S	584_V	0.735	0.68
186_K	569_S	0.732	0.67
6_C	89_T	0.730	0.67
143_K	258_E	0.729	0.67
340_F	409_L	0.727	0.67
294_D	317_R	0.727	0.67
283_K	481_Y	0.725	0.67
483_V	533_F	0.723	0.66
45_V	92_I	0.722	0.66
55_D	58_K	0.722	0.66
377_I	381_L	0.721	0.66
226_Q	484_G	0.719	0.66
165_L	178_V	0.717	0.66
407_G	411_L	0.715	0.66
4_E	8_Q	0.713	0.65
395_G	405_A	0.713	0.65
146_S	159_D	0.712	0.65
449_H	473_A	0.711	0.65
128_D	131_R	0.708	0.65
255_L	542_L	0.708	0.65
34_I	64_R	0.707	0.65
187_F	581_I	0.707	0.65
274_E	279_Y	0.707	0.65
62_E	101_I	0.707	0.65
19_T	70_Q	0.705	0.64
378_E	381_L	0.705	0.64
418_G	421_D	0.704	0.64
116_N	131_R	0.703	0.64
500_F	521_L	0.703	0.64
521_L	525_T	0.699	0.64
574_T	577_A	0.698	0.64
227_P	230_T	0.698	0.64
295_V	298_L	0.696	0.63
299_L	308_A	0.695	0.63
461_E	465_A	0.695	0.63
397_D	402_V	0.695	0.63
398_N	439_D	0.695	0.63
11_L	83_I	0.694	0.63
110_L	120_A	0.694	0.63
212_I	535_L	0.692	0.63
334_I	391_M	0.692	0.63
33_L	395_G	0.691	0.63
476_M	484_G	0.691	0.63
84_N	90_G	0.690	0.63
253_R	263_D	0.688	0.63
137_R	547_N	0.687	0.62
151_F	247_V	0.687	0.62
188_Y	560_A	0.686	0.62
337_Y	412_K	0.686	0.62
239_M	491_H	0.685	0.62
252_V	483_V	0.684	0.62
380_I	384_T	0.682	0.62
333_Q	336_E	0.682	0.62
278_R	289_P	0.680	0.62
276_E	281_S	0.679	0.62
293_T	385_A	0.679	0.62
69_I	99_L	0.679	0.62
262_V	425_W	0.678	0.61
168_A	171_E	0.677	0.61
152_M	232_I	0.677	0.61
270_M	278_R	0.676	0.61
36_I	69_I	0.675	0.61
18_V	75_V	0.674	0.61
122_L	563_L	0.674	0.61
453_S	456_D	0.674	0.61
459_A	498_T	0.673	0.61
372_L	377_I	0.672	0.61
326_G	417_L	0.670	0.60
24_V	63_L	0.670	0.60
478_I	547_N	0.667	0.60
126_Y	200_L	0.663	0.60
458_T	462_L	0.663	0.60
24_V	36_I	0.662	0.60
142_A	210_Y	0.661	0.59
296_A	317_R	0.661	0.59
79_D	83_I	0.660	0.59
176_Y	183_H	0.658	0.59
386_A	389_G	0.658	0.59
322_R	326_G	0.657	0.59
350_A	368_V	0.656	0.59
409_L	413_V	0.656	0.59
232_I	248_M	0.655	0.59
438_D	444_L	0.654	0.59
226_Q	496_Q	0.649	0.58
186_K	580_S	0.648	0.58
513_K	572_N	0.648	0.58
457_M	463_K	0.647	0.58
303_E	376_I	0.645	0.58
102_I	527_P	0.642	0.57
319_A	399_K	0.642	0.57
294_D	297_D	0.642	0.57
323_V	393_F	0.641	0.57
381_L	384_T	0.641	0.57
151_F	254_H	0.640	0.57
339_N	343_I	0.640	0.57
241_A	431_I	0.639	0.57
152_M	531_L	0.637	0.57
449_H	452_T	0.636	0.57
462_L	495_M	0.635	0.56
452_T	473_A	0.635	0.56
196_L	517_L	0.635	0.56
303_E	373_N	0.635	0.56
176_Y	227_P	0.633	0.56
44_I	87_M	0.633	0.56
42_E	139_K	0.632	0.56
502_I	505_I	0.631	0.56
10_R	89_T	0.630	0.56
300_K	383_R	0.630	0.56
491_H	521_L	0.629	0.56
253_R	264_L	0.627	0.55
330_T	336_E	0.627	0.55
472_N	488_V	0.626	0.55
252_V	264_L	0.626	0.55
508_E	512_E	0.626	0.55
503_L	506_N	0.626	0.55
116_N	133_E	0.625	0.55
226_Q	487_S	0.625	0.55
310_P	318_V	0.625	0.55
166_T	567_A	0.624	0.55
511_R	518_L	0.624	0.55
306_V	347_K	0.623	0.55
277_R	317_R	0.623	0.55
105_A	108_L	0.623	0.55
281_S	408_A	0.623	0.55
450_P	503_L	0.623	0.55
281_S	428_L	0.622	0.55
84_N	87_M	0.620	0.55
248_M	251_L	0.620	0.55
327_A	353_K	0.618	0.54
156_G	207_D	0.617	0.54
214_K	232_I	0.616	0.54
290_M	419_L	0.616	0.54
171_E	191_P	0.615	0.54
10_R	14_V	0.615	0.54
256_W	427_P	0.614	0.54
352_I	364_I	0.614	0.54
497_Q	501_G	0.614	0.54
161_E	230_T	0.614	0.54
332_K	335_D	0.613	0.54
301_S	379_D	0.613	0.54
260_K	544_G	0.612	0.54
234_V	247_V	0.612	0.54
279_Y	289_P	0.611	0.54
213_V	472_N	0.610	0.53
288_N	420_T	0.609	0.53
9_L	88_A	0.609	0.53
4_E	45_V	0.608	0.53
573_P	582_Q	0.608	0.53
168_A	175_D	0.607	0.53
428_L	476_M	0.606	0.53
7_G	45_V	0.605	0.53
147_L	151_F	0.604	0.53
446_A	503_L	0.603	0.53
183_H	561_A	0.602	0.52
30_L	37_D	0.602	0.52
513_K	581_I	0.600	0.52
160_I	553_A	0.599	0.52
354_V	388_D	0.599	0.52
59_L	100_T	0.598	0.52
453_S	488_V	0.598	0.52
449_H	490_I	0.596	0.52
145_T	148_V	0.596	0.52
249_E	269_V	0.596	0.52
226_Q	556_K	0.595	0.52
63_L	99_L	0.594	0.52
316_G	396_A	0.594	0.52
239_M	247_V	0.592	0.51
256_W	260_K	0.592	0.51
497_Q	511_R	0.592	0.51
120_A	123_K	0.591	0.51
200_L	521_L	0.591	0.51
277_R	292_L	0.591	0.51
68_C	105_A	0.591	0.51
548_I	552_I	0.591	0.51
571_A	575_A	0.590	0.51
122_L	557_T	0.590	0.51
325_G	390_D	0.590	0.51
251_L	254_H	0.589	0.51
166_T	196_L	0.589	0.51
367_P	394_F	0.588	0.51
30_L	81_K	0.587	0.51
159_D	197_F	0.587	0.51
286_L	289_P	0.587	0.51
447_M	453_S	0.586	0.51
21_C	366_S	0.586	0.51
244_V	248_M	0.586	0.51
45_V	89_T	0.586	0.51
259_V	270_M	0.585	0.50
460_A	498_T	0.585	0.50
49_F	69_I	0.584	0.50
161_E	226_Q	0.584	0.50
26_R	30_L	0.583	0.50
9_L	42_E	0.583	0.50
12_S	16_Q	0.583	0.50
249_E	266_D	0.582	0.50
114_H	133_E	0.582	0.50
561_A	566_E	0.582	0.50
139_K	206_F	0.582	0.50
462_L	498_T	0.581	0.50
320_A	350_A	0.581	0.50
232_I	251_L	0.581	0.50
136_Q	139_K	0.580	0.50
379_D	383_R	0.579	0.50
404_D	408_A	0.579	0.50
241_A	488_V	0.578	0.50
184_K	583_V	0.578	0.50
326_G	391_M	0.578	0.50
250_A	253_R	0.575	0.49
322_R	390_D	0.575	0.49
421_D	544_G	0.575	0.49
404_D	407_G	0.575	0.49
34_I	57_L	0.574	0.49
450_P	485_G	0.573	0.49
302_V	380_I	0.572	0.49
181_R	220_D	0.572	0.49
323_V	413_V	0.570	0.49
104_R	492_N	0.570	0.49
193_S	496_Q	0.570	0.49
519_D	564_M	0.570	0.49
50_D	53_R	0.569	0.49
332_K	353_K	0.568	0.48
447_M	473_A	0.568	0.48
364_I	369_A	0.567	0.48
221_L	484_G	0.566	0.48
422_E	546_D	0.566	0.48
449_H	496_Q	0.565	0.48
452_T	485_G	0.564	0.48
340_F	343_I	0.564	0.48
425_W	479_N	0.563	0.48
234_V	533_F	0.563	0.48
136_Q	143_K	0.563	0.48
548_I	551_V	0.562	0.48
298_L	376_I	0.562	0.48
411_L	428_L	0.562	0.48
41_R	158_L	0.561	0.48
18_V	45_V	0.561	0.48
481_Y	484_G	0.560	0.47
27_R	67_F	0.560	0.47
264_L	427_P	0.559	0.47
460_A	464_A	0.559	0.47
323_V	327_A	0.558	0.47
20_L	75_V	0.558	0.47
16_Q	74_T	0.558	0.47
77_A	80_E	0.557	0.47
368_V	371_F	0.555	0.47
344_Y	404_D	0.555	0.47
517_L	521_L	0.554	0.47
519_D	523_Y	0.554	0.47
252_V	531_L	0.554	0.47
175_D	189_A	0.553	0.47
275_A	430_V	0.553	0.47
518_L	522_K	0.553	0.47
341_V	344_Y	0.553	0.47
334_I	353_K	0.553	0.47
160_I	214_K	0.552	0.47
517_L	525_T	0.552	0.47
258_E	263_D	0.550	0.46
401_I	405_A	0.550	0.46
230_T	556_K	0.550	0.46
570_F	583_V	0.549	0.46
78_R	90_G	0.549	0.46
296_A	318_V	0.549	0.46
65_N	111_D	0.548	0.46
161_E	169_T	0.548	0.46
497_Q	522_K	0.546	0.46
310_P	315_K	0.546	0.46
258_E	262_V	0.546	0.46
140_T	260_K	0.545	0.46
366_S	369_A	0.544	0.46
436_F	447_M	0.544	0.46
12_S	91_E	0.543	0.45
30_L	82_N	0.542	0.45
267_F	476_M	0.542	0.45
334_I	393_F	0.542	0.45
193_S	226_Q	0.542	0.45
139_K	160_I	0.541	0.45
174_R	220_D	0.541	0.45
245_R	248_M	0.541	0.45
307_F	350_A	0.540	0.45
329_L	333_Q	0.540	0.45
457_M	462_L	0.539	0.45
171_E	514_F	0.539	0.45
365_N	521_L	0.539	0.45
337_Y	393_F	0.538	0.45
76_R	79_D	0.538	0.45
446_A	510_Q	0.538	0.45
446_A	485_G	0.538	0.45
352_I	394_F	0.537	0.45
166_T	175_D	0.537	0.45
27_R	33_L	0.537	0.45
32_S	50_D	0.537	0.45
23_W	238_F	0.535	0.44
364_I	377_I	0.535	0.44
325_G	387_Q	0.534	0.44
189_A	514_F	0.533	0.44
245_R	476_M	0.533	0.44
253_R	267_F	0.532	0.44
197_F	567_A	0.532	0.44
427_P	483_V	0.532	0.44
330_T	339_N	0.532	0.44
325_G	389_G	0.532	0.44
56_A	63_L	0.531	0.44
460_A	468_N	0.531	0.44
224_D	549_R	0.530	0.44
315_K	319_A	0.529	0.44
484_G	487_S	0.528	0.44
331_R	370_K	0.528	0.44
68_C	525_T	0.527	0.44
545_T	551_V	0.527	0.44
226_Q	230_T	0.527	0.44
33_L	48_F	0.526	0.43
169_T	226_Q	0.526	0.43
126_Y	519_D	0.526	0.43
138_L	553_A	0.525	0.43
372_L	376_I	0.524	0.43
443_G	485_G	0.524	0.43
414_G	420_T	0.524	0.43
352_I	365_N	0.523	0.43
485_G	531_L	0.522	0.43
230_T	496_Q	0.522	0.43
108_L	111_D	0.522	0.43
281_S	411_L	0.521	0.43
111_D	114_H	0.521	0.43
288_N	419_L	0.520	0.43
257_L	264_L	0.520	0.43
227_P	556_K	0.519	0.43
143_K	156_G	0.518	0.42
292_L	402_V	0.517	0.42
13_H	92_I	0.517	0.42
110_L	113_N	0.517	0.42
260_K	425_W	0.516	0.42
420_T	423_S	0.516	0.42
281_S	403_A	0.514	0.42
15_G	77_A	0.514	0.42
196_L	510_Q	0.514	0.42
543_T	551_V	0.513	0.42
353_K	364_I	0.513	0.42
112_S	521_L	0.513	0.42
8_Q	88_A	0.512	0.42
10_R	92_I	0.512	0.42
123_K	519_D	0.512	0.42
4_E	18_V	0.511	0.42
308_A	376_I	0.510	0.42
397_D	406_M	0.510	0.42
354_V	391_M	0.510	0.42
254_H	257_L	0.510	0.42
435_M	466_P	0.509	0.41
478_I	481_Y	0.509	0.41
337_Y	416_D	0.509	0.41
36_I	96_A	0.509	0.41
452_T	496_Q	0.508	0.41
166_T	216_F	0.508	0.41
539_T	545_T	0.507	0.41
79_D	87_M	0.507	0.41
157_F	208_R	0.507	0.41
297_D	382_D	0.507	0.41
504_G	507_E	0.505	0.41
347_K	350_A	0.505	0.41
221_L	227_P	0.505	0.41
299_L	377_I	0.505	0.41
346_A	405_A	0.504	0.41
136_Q	140_T	0.504	0.41
119_E	183_H	0.504	0.41
131_R	335_D	0.504	0.41
230_T	484_G	0.503	0.41
487_S	496_Q	0.503	0.41
29_D	51_P	0.503	0.41
366_S	377_I	0.502	0.41
426_A	478_I	0.502	0.41
68_C	103_N	0.502	0.41
402_V	405_A	0.502	0.41
509_E	512_E	0.502	0.41
183_H	186_K	0.501	0.40
63_L	67_F	0.500	0.40
535_L	539_T	0.500	0.40

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4rmfA	2	0.9627	100	0.24	Contact Map
1c0aA	1	0.9915	100	0.256	Contact Map
4wj4A	2	0.9864	100	0.261	Contact Map
1l0wA	2	0.9644	100	0.273	Contact Map
4ah6A	2	0.961	100	0.339	Contact Map
4up7A	2	0.7814	100	0.51	Contact Map
3i7fA	2	0.7085	100	0.519	Contact Map
1eovA	2	0.7475	100	0.527	Contact Map
4ex5A	2	0.7271	100	0.53	Contact Map
1e1oA	2	0.7169	100	0.537	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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