GREMLIN Database
SYD - Aspartate--tRNA ligase
UniProt: P21889 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10097
Length: 590 (573)
Sequences: 3300 (1639)
Seq/√Len: 68.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
13_H16_Q5.1911.00
278_R291_E5.0211.00
151_F250_A4.2381.00
47_V96_A3.9791.00
488_V529_A3.9741.00
11_L91_E3.9381.00
324_P387_Q3.8801.00
148_V232_I3.7931.00
297_D383_R3.6721.00
146_S150_R3.6091.00
286_L426_A3.5001.00
17_Q72_T3.3001.00
106_D522_K3.1481.00
257_L263_D3.1231.00
412_K416_D3.0851.00
70_Q100_T3.0151.00
72_T98_S2.9051.00
145_T535_L2.7971.00
465_A468_N2.7951.00
252_V476_M2.7891.00
164_M213_V2.7641.00
421_D424_K2.7301.00
511_R519_D2.6871.00
155_H250_A2.6771.00
63_L69_I2.6421.00
10_R13_H2.6381.00
140_T543_T2.6251.00
241_A472_N2.5711.00
164_M216_F2.5131.00
160_I206_F2.4531.00
573_P577_A2.4501.00
432_D455_K2.4131.00
176_Y560_A2.3931.00
20_L94_V2.3611.00
461_E468_N2.3151.00
77_A83_I2.3071.00
463_K498_T2.2731.00
19_T72_T2.2501.00
320_A384_T2.2451.00
242_P269_V2.2431.00
17_Q97_S2.1931.00
444_L467_E2.1761.00
273_A470_V2.1651.00
147_L258_E2.1301.00
10_R88_A2.1181.00
271_T274_E2.0991.00
176_Y182_V2.0641.00
20_L45_V2.0621.00
268_P426_A2.0511.00
507_E511_R2.0461.00
279_Y291_E2.0421.00
488_V491_H2.0281.00
236_T239_M2.0271.00
83_I91_E2.0001.00
274_E278_R1.9991.00
286_L428_L1.9591.00
144_I539_T1.9571.00
14_V77_A1.9541.00
357_R388_D1.9521.00
273_A277_R1.9391.00
438_D441_E1.9341.00
320_A392_I1.9311.00
339_N342_K1.9271.00
146_S153_D1.9111.00
239_M244_V1.9051.00
271_T432_D1.8881.00
331_R335_D1.8881.00
17_Q74_T1.8781.00
281_S407_G1.8771.00
497_Q507_E1.8661.00
186_K570_F1.8611.00
142_A153_D1.8531.00
76_R95_L1.8421.00
288_N411_L1.8041.00
248_M533_F1.8011.00
21_C70_Q1.7981.00
153_D210_Y1.7941.00
356_E388_D1.7701.00
47_V71_V1.7661.00
139_K158_L1.7661.00
5_Y42_E1.7631.00
456_D472_N1.7571.00
234_V531_L1.7561.00
184_K580_S1.7471.00
42_E45_V1.7471.00
562_C565_T1.7461.00
270_M428_L1.7411.00
177_L571_A1.7401.00
373_N376_I1.7321.00
254_H258_E1.7281.00
138_L206_F1.7271.00
9_L92_I1.7111.00
74_T97_S1.7081.00
196_L516_F1.7051.00
11_L14_V1.7001.00
501_G507_E1.6981.00
427_P478_I1.6931.00
298_L383_R1.6911.00
438_D445_T1.6911.00
244_V529_A1.6891.00
335_D338_G1.6841.00
545_T550_D1.6790.99
292_L319_A1.6710.99
253_R265_G1.6610.99
506_N509_E1.6610.99
137_R545_T1.6530.99
45_V94_V1.6490.99
147_L254_H1.6470.99
9_L13_H1.6460.99
577_A584_V1.6320.99
323_V326_G1.6310.99
32_S51_P1.6260.99
159_D210_Y1.6260.99
75_V94_V1.5990.99
505_I513_K1.5970.99
154_D254_H1.5970.99
458_T470_V1.5920.99
505_I510_Q1.5840.99
277_R294_D1.5830.99
151_F155_H1.5790.99
152_M234_V1.5770.99
483_V538_L1.5650.99
341_V409_L1.5500.99
232_I535_L1.5470.99
455_K470_V1.5400.99
463_K501_G1.5370.99
270_M430_V1.5360.99
5_Y45_V1.5340.99
478_I483_V1.5330.99
150_R153_D1.5100.99
295_V380_I1.5070.99
42_E207_D1.5000.99
239_M243_Q1.4980.99
256_W425_W1.4960.99
256_W542_L1.4880.99
303_E308_A1.4870.99
240_T243_Q1.4810.99
353_K365_N1.4750.99
24_V69_I1.4730.99
437_E447_M1.4680.99
103_N525_T1.4650.99
378_E382_D1.4630.99
9_L18_V1.4540.99
129_L204_S1.4470.98
275_A281_S1.4440.98
20_L38_M1.4420.98
75_V92_I1.4170.98
148_V535_L1.4140.98
145_T232_I1.4130.98
510_Q518_L1.4020.98
379_D382_D1.4000.98
493_G522_K1.3920.98
59_L99_L1.3830.98
139_K143_K1.3810.98
18_V94_V1.3780.98
295_V299_L1.3780.98
323_V417_L1.3760.98
435_M499_V1.3670.98
15_G74_T1.3540.98
481_Y547_N1.3530.98
239_M488_V1.3380.97
399_K403_A1.3360.97
267_F427_P1.3350.97
234_V248_M1.3160.97
341_V405_A1.3150.97
441_E445_T1.3100.97
245_R269_V1.3060.97
260_K542_L1.3010.97
241_A245_R1.3010.97
9_L45_V1.3000.97
70_Q102_I1.3000.97
169_T516_F1.2920.97
317_R403_A1.2900.97
182_V560_A1.2880.97
476_M533_F1.2870.97
319_A403_A1.2820.97
166_T197_F1.2750.97
462_L469_A1.2670.96
493_G497_Q1.2660.96
2_R207_D1.2510.96
423_S544_G1.2500.96
144_I259_V1.2450.96
148_V251_L1.2360.96
301_S308_A1.2310.96
135_A206_F1.2250.96
144_I535_L1.2200.96
164_M214_K1.2170.95
5_Y207_D1.2140.95
242_P245_R1.2130.95
168_A571_A1.2080.95
267_F428_L1.2070.95
453_S495_M1.2070.95
239_M529_A1.2050.95
80_E83_I1.2030.95
150_R154_D1.2020.95
143_K146_S1.2000.95
167_K569_S1.1950.95
56_A99_L1.1910.95
374_A378_E1.1840.95
144_I255_L1.1750.95
11_L77_A1.1650.94
317_R399_K1.1610.94
270_M275_A1.1550.94
332_K336_E1.1540.94
295_V320_A1.1520.94
240_T472_N1.1500.94
27_R64_R1.1500.94
36_I49_F1.1470.94
304_F307_F1.1450.94
160_I201_L1.1440.94
133_E545_T1.1420.94
137_R543_T1.1410.94
376_I379_D1.1400.94
458_T461_E1.1340.93
350_A394_F1.1330.93
386_A392_I1.1310.93
542_L547_N1.1270.93
196_L565_T1.1260.93
96_A99_L1.1250.93
297_D300_K1.1220.93
305_A309_G1.1220.93
492_N495_M1.1210.93
135_A139_K1.1200.93
509_E513_K1.1110.93
299_L302_V1.1070.93
299_L318_V1.1030.92
77_A91_E1.1010.92
242_P246_E1.1010.92
4_E13_H1.1000.92
147_L259_V1.0990.92
155_H247_V1.0980.92
322_R392_I1.0960.92
439_D443_G1.0930.92
57_L61_S1.0900.92
79_D82_N1.0900.92
461_E464_A1.0840.92
459_A463_K1.0830.92
253_R266_D1.0780.92
438_D443_G1.0740.91
288_N414_G1.0710.91
144_I542_L1.0700.91
459_A495_M1.0680.91
132_P136_Q1.0680.91
4_E16_Q1.0670.91
152_M251_L1.0650.91
277_R319_A1.0640.91
166_T564_M1.0630.91
4_E9_L1.0620.91
147_L255_L1.0540.91
400_K404_D1.0510.91
473_A485_G1.0500.90
183_H560_A1.0480.90
39_R66_E1.0450.90
50_D76_R1.0440.90
571_A576_L1.0430.90
355_N365_N1.0420.90
374_A377_I1.0390.90
322_R387_Q1.0380.90
168_A575_A1.0380.90
580_S583_V1.0340.90
8_Q13_H1.0300.90
295_V394_F1.0300.90
344_Y408_A1.0300.90
255_L259_V1.0300.90
166_T565_T1.0290.90
129_L206_F1.0240.89
45_V75_V1.0240.89
302_V376_I1.0240.89
85_R91_E1.0220.89
336_E339_N1.0220.89
354_V386_A1.0200.89
203_M521_L1.0180.89
333_Q416_D1.0180.89
397_D401_I1.0170.89
286_L424_K1.0150.89
261_G264_L1.0150.89
412_K415_K1.0080.89
149_R159_D1.0040.88
8_Q42_E1.0040.88
453_S472_N1.0020.88
398_N401_I1.0010.88
384_T392_I1.0000.88
246_E250_A1.0000.88
58_K61_S0.9990.88
201_L553_A0.9990.88
438_D442_G0.9970.88
557_T561_A0.9960.88
156_G208_R0.9960.88
290_M323_V0.9940.88
150_R258_E0.9940.88
147_L150_R0.9940.88
71_V96_A0.9930.88
573_P584_V0.9900.88
340_F412_K0.9860.87
432_D470_V0.9840.87
236_T244_V0.9820.87
449_H487_S0.9790.87
115_V133_E0.9740.87
62_E104_R0.9730.87
574_T578_E0.9710.87
329_L417_L0.9700.87
121_R128_D0.9700.87
10_R91_E0.9690.87
498_T501_G0.9650.86
49_F96_A0.9610.86
446_A499_V0.9610.86
347_K397_D0.9600.86
344_Y405_A0.9590.86
133_E137_R0.9560.86
203_M525_T0.9530.86
74_T95_L0.9520.86
322_R384_T0.9500.85
381_L386_A0.9500.85
244_V488_V0.9470.85
455_K472_N0.9460.85
364_I381_L0.9440.85
49_F99_L0.9430.85
539_T543_T0.9400.85
60_A99_L0.9360.85
464_A468_N0.9330.84
352_I369_A0.9320.84
7_G10_R0.9320.84
197_F565_T0.9270.84
301_S376_I0.9270.84
151_F251_L0.9250.84
126_Y564_M0.9200.84
274_E277_R0.9190.83
197_F562_C0.9160.83
27_R34_I0.9150.83
484_G533_F0.9120.83
64_R67_F0.9110.83
354_V392_I0.9090.83
557_T563_L0.9090.83
182_V188_Y0.9080.83
340_F344_Y0.9070.83
302_V308_A0.9060.83
148_V255_L0.9060.83
466_P469_A0.9050.83
415_K422_E0.9030.82
5_Y8_Q0.9030.82
145_T212_I0.9020.82
545_T548_I0.9010.82
310_P316_G0.8990.82
146_S210_Y0.8970.82
6_C207_D0.8950.82
155_H208_R0.8930.82
140_T259_V0.8920.82
289_P321_L0.8910.82
420_T424_K0.8900.81
358_A388_D0.8890.81
143_K153_D0.8890.81
9_L91_E0.8850.81
547_N550_D0.8850.81
457_M460_A0.8840.81
447_M471_A0.8820.81
268_P271_T0.8800.81
140_T144_I0.8800.81
8_Q45_V0.8800.81
160_I204_S0.8790.81
572_N575_A0.8790.81
433_F447_M0.8780.81
293_T384_T0.8780.81
252_V533_F0.8770.81
511_R522_K0.8770.81
260_K264_L0.8770.81
460_A463_K0.8750.80
38_M69_I0.8750.80
373_N377_I0.8740.80
112_S127_L0.8740.80
244_V247_V0.8730.80
248_M531_L0.8680.80
352_I366_S0.8660.80
161_E214_K0.8650.80
338_G342_K0.8630.79
138_L160_I0.8620.79
203_M517_L0.8620.79
152_M210_Y0.8620.79
278_R292_L0.8610.79
41_R139_K0.8610.79
59_L62_E0.8610.79
268_P286_L0.8580.79
411_L414_G0.8580.79
142_A146_S0.8580.79
258_E261_G0.8570.79
260_K263_D0.8570.79
25_N113_N0.8560.79
29_D32_S0.8550.79
5_Y9_L0.8550.79
317_R402_V0.8550.79
293_T322_R0.8530.79
257_L261_G0.8510.79
266_D269_V0.8500.78
123_K566_E0.8500.78
236_T243_Q0.8500.78
455_K458_T0.8500.78
395_G406_M0.8490.78
435_M446_A0.8480.78
459_A462_L0.8470.78
58_K62_E0.8460.78
145_T159_D0.8450.78
490_I499_V0.8440.78
481_Y541_L0.8440.78
346_A349_L0.8420.78
49_F60_A0.8400.78
322_R385_A0.8380.77
457_M461_E0.8380.77
104_R494_D0.8370.77
421_D426_A0.8330.77
36_I63_L0.8280.77
271_T431_I0.8260.76
67_F101_I0.8250.76
299_L380_I0.8240.76
354_V364_I0.8240.76
25_N44_I0.8230.76
461_E466_P0.8190.76
322_R386_A0.8190.76
9_L20_L0.8180.76
382_D385_A0.8130.75
245_R485_G0.8100.75
274_E291_E0.8100.75
355_N358_A0.8090.75
354_V381_L0.8090.75
113_N116_N0.8080.75
431_I455_K0.8050.75
186_K561_A0.8040.74
38_M47_V0.8040.74
375_E378_E0.8030.74
71_V94_V0.8030.74
168_A189_A0.8030.74
30_L33_L0.8030.74
3_T19_T0.8000.74
418_G422_E0.7990.74
481_Y540_M0.7960.74
299_L376_I0.7950.74
510_Q517_L0.7900.73
413_V417_L0.7890.73
241_A455_K0.7890.73
349_L393_F0.7870.73
323_V329_L0.7870.73
10_R45_V0.7850.73
283_K407_G0.7820.72
293_T383_R0.7810.72
292_L403_A0.7800.72
457_M470_V0.7790.72
111_D116_N0.7790.72
21_C100_T0.7750.72
415_K420_T0.7740.72
411_L415_K0.7720.71
13_H45_V0.7710.71
175_D191_P0.7700.71
117_T120_A0.7700.71
50_D95_L0.7690.71
133_E550_D0.7680.71
249_E267_F0.7660.71
436_F499_V0.7650.71
135_A160_I0.7640.71
326_G329_L0.7640.71
577_A582_Q0.7620.70
166_T562_C0.7620.70
319_A406_M0.7610.70
183_H580_S0.7590.70
150_R254_H0.7570.70
13_H89_T0.7550.70
224_D481_Y0.7540.70
277_R403_A0.7510.69
461_E469_A0.7510.69
252_V538_L0.7500.69
42_E156_G0.7490.69
49_F63_L0.7480.69
30_L558_T0.7460.69
462_L466_P0.7460.69
37_D87_M0.7460.69
277_R399_K0.7460.69
248_M476_M0.7450.69
9_L94_V0.7450.69
158_L206_F0.7440.69
395_G402_V0.7430.68
375_E379_D0.7420.68
305_A308_A0.7410.68
485_G532_A0.7400.68
49_F53_R0.7390.68
330_T333_Q0.7380.68
436_F502_I0.7370.68
200_L564_M0.7350.68
441_E574_T0.7350.68
580_S584_V0.7350.68
186_K569_S0.7320.67
6_C89_T0.7300.67
143_K258_E0.7290.67
340_F409_L0.7270.67
294_D317_R0.7270.67
283_K481_Y0.7250.67
483_V533_F0.7230.66
45_V92_I0.7220.66
55_D58_K0.7220.66
377_I381_L0.7210.66
226_Q484_G0.7190.66
165_L178_V0.7170.66
407_G411_L0.7150.66
4_E8_Q0.7130.65
395_G405_A0.7130.65
146_S159_D0.7120.65
449_H473_A0.7110.65
128_D131_R0.7080.65
255_L542_L0.7080.65
34_I64_R0.7070.65
187_F581_I0.7070.65
274_E279_Y0.7070.65
62_E101_I0.7070.65
19_T70_Q0.7050.64
378_E381_L0.7050.64
418_G421_D0.7040.64
116_N131_R0.7030.64
500_F521_L0.7030.64
521_L525_T0.6990.64
574_T577_A0.6980.64
227_P230_T0.6980.64
295_V298_L0.6960.63
299_L308_A0.6950.63
461_E465_A0.6950.63
397_D402_V0.6950.63
398_N439_D0.6950.63
11_L83_I0.6940.63
110_L120_A0.6940.63
212_I535_L0.6920.63
334_I391_M0.6920.63
33_L395_G0.6910.63
476_M484_G0.6910.63
84_N90_G0.6900.63
253_R263_D0.6880.63
137_R547_N0.6870.62
151_F247_V0.6870.62
188_Y560_A0.6860.62
337_Y412_K0.6860.62
239_M491_H0.6850.62
252_V483_V0.6840.62
380_I384_T0.6820.62
333_Q336_E0.6820.62
278_R289_P0.6800.62
276_E281_S0.6790.62
293_T385_A0.6790.62
69_I99_L0.6790.62
262_V425_W0.6780.61
168_A171_E0.6770.61
152_M232_I0.6770.61
270_M278_R0.6760.61
36_I69_I0.6750.61
18_V75_V0.6740.61
122_L563_L0.6740.61
453_S456_D0.6740.61
459_A498_T0.6730.61
372_L377_I0.6720.61
326_G417_L0.6700.60
24_V63_L0.6700.60
478_I547_N0.6670.60
126_Y200_L0.6630.60
458_T462_L0.6630.60
24_V36_I0.6620.60
142_A210_Y0.6610.59
296_A317_R0.6610.59
79_D83_I0.6600.59
176_Y183_H0.6580.59
386_A389_G0.6580.59
322_R326_G0.6570.59
350_A368_V0.6560.59
409_L413_V0.6560.59
232_I248_M0.6550.59
438_D444_L0.6540.59
226_Q496_Q0.6490.58
186_K580_S0.6480.58
513_K572_N0.6480.58
457_M463_K0.6470.58
303_E376_I0.6450.58
102_I527_P0.6420.57
319_A399_K0.6420.57
294_D297_D0.6420.57
323_V393_F0.6410.57
381_L384_T0.6410.57
151_F254_H0.6400.57
339_N343_I0.6400.57
241_A431_I0.6390.57
152_M531_L0.6370.57
449_H452_T0.6360.57
462_L495_M0.6350.56
452_T473_A0.6350.56
196_L517_L0.6350.56
303_E373_N0.6350.56
176_Y227_P0.6330.56
44_I87_M0.6330.56
42_E139_K0.6320.56
502_I505_I0.6310.56
10_R89_T0.6300.56
300_K383_R0.6300.56
491_H521_L0.6290.56
253_R264_L0.6270.55
330_T336_E0.6270.55
472_N488_V0.6260.55
252_V264_L0.6260.55
508_E512_E0.6260.55
503_L506_N0.6260.55
116_N133_E0.6250.55
226_Q487_S0.6250.55
310_P318_V0.6250.55
166_T567_A0.6240.55
511_R518_L0.6240.55
306_V347_K0.6230.55
277_R317_R0.6230.55
105_A108_L0.6230.55
281_S408_A0.6230.55
450_P503_L0.6230.55
281_S428_L0.6220.55
84_N87_M0.6200.55
248_M251_L0.6200.55
327_A353_K0.6180.54
156_G207_D0.6170.54
214_K232_I0.6160.54
290_M419_L0.6160.54
171_E191_P0.6150.54
10_R14_V0.6150.54
256_W427_P0.6140.54
352_I364_I0.6140.54
497_Q501_G0.6140.54
161_E230_T0.6140.54
332_K335_D0.6130.54
301_S379_D0.6130.54
260_K544_G0.6120.54
234_V247_V0.6120.54
279_Y289_P0.6110.54
213_V472_N0.6100.53
288_N420_T0.6090.53
9_L88_A0.6090.53
4_E45_V0.6080.53
573_P582_Q0.6080.53
168_A175_D0.6070.53
428_L476_M0.6060.53
7_G45_V0.6050.53
147_L151_F0.6040.53
446_A503_L0.6030.53
183_H561_A0.6020.52
30_L37_D0.6020.52
513_K581_I0.6000.52
160_I553_A0.5990.52
354_V388_D0.5990.52
59_L100_T0.5980.52
453_S488_V0.5980.52
449_H490_I0.5960.52
145_T148_V0.5960.52
249_E269_V0.5960.52
226_Q556_K0.5950.52
63_L99_L0.5940.52
316_G396_A0.5940.52
239_M247_V0.5920.51
256_W260_K0.5920.51
497_Q511_R0.5920.51
120_A123_K0.5910.51
200_L521_L0.5910.51
277_R292_L0.5910.51
68_C105_A0.5910.51
548_I552_I0.5910.51
571_A575_A0.5900.51
122_L557_T0.5900.51
325_G390_D0.5900.51
251_L254_H0.5890.51
166_T196_L0.5890.51
367_P394_F0.5880.51
30_L81_K0.5870.51
159_D197_F0.5870.51
286_L289_P0.5870.51
447_M453_S0.5860.51
21_C366_S0.5860.51
244_V248_M0.5860.51
45_V89_T0.5860.51
259_V270_M0.5850.50
460_A498_T0.5850.50
49_F69_I0.5840.50
161_E226_Q0.5840.50
26_R30_L0.5830.50
9_L42_E0.5830.50
12_S16_Q0.5830.50
249_E266_D0.5820.50
114_H133_E0.5820.50
561_A566_E0.5820.50
139_K206_F0.5820.50
462_L498_T0.5810.50
320_A350_A0.5810.50
232_I251_L0.5810.50
136_Q139_K0.5800.50
379_D383_R0.5790.50
404_D408_A0.5790.50
241_A488_V0.5780.50
184_K583_V0.5780.50
326_G391_M0.5780.50
250_A253_R0.5750.49
322_R390_D0.5750.49
421_D544_G0.5750.49
404_D407_G0.5750.49
34_I57_L0.5740.49
450_P485_G0.5730.49
302_V380_I0.5720.49
181_R220_D0.5720.49
323_V413_V0.5700.49
104_R492_N0.5700.49
193_S496_Q0.5700.49
519_D564_M0.5700.49
50_D53_R0.5690.49
332_K353_K0.5680.48
447_M473_A0.5680.48
364_I369_A0.5670.48
221_L484_G0.5660.48
422_E546_D0.5660.48
449_H496_Q0.5650.48
452_T485_G0.5640.48
340_F343_I0.5640.48
425_W479_N0.5630.48
234_V533_F0.5630.48
136_Q143_K0.5630.48
548_I551_V0.5620.48
298_L376_I0.5620.48
411_L428_L0.5620.48
41_R158_L0.5610.48
18_V45_V0.5610.48
481_Y484_G0.5600.47
27_R67_F0.5600.47
264_L427_P0.5590.47
460_A464_A0.5590.47
323_V327_A0.5580.47
20_L75_V0.5580.47
16_Q74_T0.5580.47
77_A80_E0.5570.47
368_V371_F0.5550.47
344_Y404_D0.5550.47
517_L521_L0.5540.47
519_D523_Y0.5540.47
252_V531_L0.5540.47
175_D189_A0.5530.47
275_A430_V0.5530.47
518_L522_K0.5530.47
341_V344_Y0.5530.47
334_I353_K0.5530.47
160_I214_K0.5520.47
517_L525_T0.5520.47
258_E263_D0.5500.46
401_I405_A0.5500.46
230_T556_K0.5500.46
570_F583_V0.5490.46
78_R90_G0.5490.46
296_A318_V0.5490.46
65_N111_D0.5480.46
161_E169_T0.5480.46
497_Q522_K0.5460.46
310_P315_K0.5460.46
258_E262_V0.5460.46
140_T260_K0.5450.46
366_S369_A0.5440.46
436_F447_M0.5440.46
12_S91_E0.5430.45
30_L82_N0.5420.45
267_F476_M0.5420.45
334_I393_F0.5420.45
193_S226_Q0.5420.45
139_K160_I0.5410.45
174_R220_D0.5410.45
245_R248_M0.5410.45
307_F350_A0.5400.45
329_L333_Q0.5400.45
457_M462_L0.5390.45
171_E514_F0.5390.45
365_N521_L0.5390.45
337_Y393_F0.5380.45
76_R79_D0.5380.45
446_A510_Q0.5380.45
446_A485_G0.5380.45
352_I394_F0.5370.45
166_T175_D0.5370.45
27_R33_L0.5370.45
32_S50_D0.5370.45
23_W238_F0.5350.44
364_I377_I0.5350.44
325_G387_Q0.5340.44
189_A514_F0.5330.44
245_R476_M0.5330.44
253_R267_F0.5320.44
197_F567_A0.5320.44
427_P483_V0.5320.44
330_T339_N0.5320.44
325_G389_G0.5320.44
56_A63_L0.5310.44
460_A468_N0.5310.44
224_D549_R0.5300.44
315_K319_A0.5290.44
484_G487_S0.5280.44
331_R370_K0.5280.44
68_C525_T0.5270.44
545_T551_V0.5270.44
226_Q230_T0.5270.44
33_L48_F0.5260.43
169_T226_Q0.5260.43
126_Y519_D0.5260.43
138_L553_A0.5250.43
372_L376_I0.5240.43
443_G485_G0.5240.43
414_G420_T0.5240.43
352_I365_N0.5230.43
485_G531_L0.5220.43
230_T496_Q0.5220.43
108_L111_D0.5220.43
281_S411_L0.5210.43
111_D114_H0.5210.43
288_N419_L0.5200.43
257_L264_L0.5200.43
227_P556_K0.5190.43
143_K156_G0.5180.42
292_L402_V0.5170.42
13_H92_I0.5170.42
110_L113_N0.5170.42
260_K425_W0.5160.42
420_T423_S0.5160.42
281_S403_A0.5140.42
15_G77_A0.5140.42
196_L510_Q0.5140.42
543_T551_V0.5130.42
353_K364_I0.5130.42
112_S521_L0.5130.42
8_Q88_A0.5120.42
10_R92_I0.5120.42
123_K519_D0.5120.42
4_E18_V0.5110.42
308_A376_I0.5100.42
397_D406_M0.5100.42
354_V391_M0.5100.42
254_H257_L0.5100.42
435_M466_P0.5090.41
478_I481_Y0.5090.41
337_Y416_D0.5090.41
36_I96_A0.5090.41
452_T496_Q0.5080.41
166_T216_F0.5080.41
539_T545_T0.5070.41
79_D87_M0.5070.41
157_F208_R0.5070.41
297_D382_D0.5070.41
504_G507_E0.5050.41
347_K350_A0.5050.41
221_L227_P0.5050.41
299_L377_I0.5050.41
346_A405_A0.5040.41
136_Q140_T0.5040.41
119_E183_H0.5040.41
131_R335_D0.5040.41
230_T484_G0.5030.41
487_S496_Q0.5030.41
29_D51_P0.5030.41
366_S377_I0.5020.41
426_A478_I0.5020.41
68_C103_N0.5020.41
402_V405_A0.5020.41
509_E512_E0.5020.41
183_H186_K0.5010.40
63_L67_F0.5000.40
535_L539_T0.5000.40
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4rmfA 2 0.9627 100 0.24 Contact Map
1c0aA 1 0.9915 100 0.256 Contact Map
4wj4A 2 0.9864 100 0.261 Contact Map
1l0wA 2 0.9644 100 0.273 Contact Map
4ah6A 2 0.961 100 0.339 Contact Map
4up7A 2 0.7814 100 0.51 Contact Map
3i7fA 2 0.7085 100 0.519 Contact Map
1eovA 2 0.7475 100 0.527 Contact Map
4ex5A 2 0.7271 100 0.53 Contact Map
1e1oA 2 0.7169 100 0.537 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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