GREMLIN Database
KDPD - Sensor protein KdpD
UniProt: P21865 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10516
Length: 894 (848)
Sequences: 1127 (735)
Seq/√Len: 25.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
57_V72_L8.0671.00
98_A106_I7.3761.00
54_D101_R6.5841.00
413_T432_Y6.1991.00
93_F98_A5.4481.00
120_R130_E5.2191.00
785_L814_V5.0311.00
90_I116_A4.7721.00
96_D120_R4.6201.00
107_L141_T4.5831.00
284_V328_V4.5331.00
191_L196_V4.4701.00
852_C863_I4.2871.00
78_L93_F4.0441.00
821_L829_I3.8851.00
413_T462_F3.8221.00
309_A314_A3.7231.00
78_L98_A3.7021.00
412_I435_G3.6851.00
76_A101_R3.6261.00
58_G98_A3.5971.00
29_F144_V3.5461.00
93_F106_I3.4481.00
812_L877_V3.4211.00
856_V877_V3.3821.00
108_M131_L3.3821.00
56_V101_R3.3581.00
686_A707_I3.2421.00
85_Y116_A3.1171.00
58_G106_I3.0741.00
53_L105_L2.9801.00
49_R76_A2.9621.00
781_V856_V2.9451.00
80_L91_S2.9031.00
57_V77_V2.8601.00
785_L877_V2.8341.00
855_I859_H2.8041.00
535_S638_V2.7560.99
95_L121_H2.7180.99
247_W336_N2.6890.99
72_L77_V2.6300.99
823_P826_E2.6060.99
95_L131_L2.5960.99
562_T565_Q2.5850.99
342_L371_L2.5520.99
82_R91_S2.5330.99
853_R857_D2.5020.99
816_D820_G2.4960.99
56_V76_A2.4260.99
659_E662_Q2.4190.98
95_L99_L2.4090.98
773_V778_F2.3990.98
129_E133_E2.3810.98
185_D212_K2.3710.98
96_D130_E2.3390.98
57_V75_L2.3150.98
460_D464_I2.3110.98
782_L786_L2.3100.98
749_L760_I2.3080.98
825_Q828_T2.2990.98
264_E304_S2.2910.98
57_V369_Q2.2800.98
810_L881_Q2.2790.98
778_F877_V2.2760.98
160_I163_R2.2600.98
172_D225_R2.2490.98
257_I263_S2.2350.97
408_L435_G2.2350.97
317_A331_Y2.2350.97
328_V340_I2.2260.97
110_E164_E2.2210.97
781_V863_I2.2130.97
866_F874_C2.2110.97
237_W243_E2.1940.97
270_A283_A2.1820.97
781_V852_C2.1780.97
93_F131_L2.1590.97
744_V773_V2.1560.97
682_L711_V2.1520.97
143_N197_Y2.1210.96
827_Q853_R2.1090.96
54_D76_A2.1080.96
83_Q760_I2.0880.96
189_Q193_E2.0720.96
321_D327_A2.0690.96
48_L53_L2.0600.96
561_L564_P2.0450.96
773_V859_H2.0430.96
798_E817_N2.0270.95
826_E867_N2.0270.95
745_V812_L2.0240.95
271_A283_A2.0190.95
99_L131_L2.0070.95
121_H130_E1.9940.95
339_K370_V1.9910.95
238_R336_N1.9840.95
797_A817_N1.9450.94
69_A73_E1.9330.94
255_L266_L1.9240.94
93_F108_M1.9220.94
28_F139_F1.9090.94
198_I201_Q1.9050.94
48_L139_F1.9020.94
197_Y205_A1.8990.93
683_F712_L1.8930.93
85_Y90_I1.8930.93
815_W874_C1.8880.93
474_D477_Y1.8820.93
188_R206_I1.8710.93
864_T876_R1.8560.93
41_M107_L1.8530.93
213_G243_E1.8500.93
145_Q164_E1.8440.92
741_L803_A1.8360.92
480_T484_M1.8270.92
26_K178_V1.8270.92
655_R659_E1.8130.92
714_T725_A1.8100.92
92_E113_H1.8100.92
461_L469_T1.7840.91
456_V484_M1.7790.91
399_I403_V1.7780.91
256_C328_V1.7680.91
48_L105_L1.7660.91
822_P825_Q1.7460.90
441_L499_R1.7460.90
213_G237_W1.7410.90
231_D249_T1.7360.90
188_R192_K1.7360.90
738_W770_L1.7120.89
813_D876_R1.7050.89
528_P642_L1.6980.89
748_A801_I1.6920.89
437_V491_I1.6840.88
418_Q470_L1.6720.88
856_V863_I1.6670.88
402_C446_W1.6660.88
211_R237_W1.6500.87
745_V801_I1.6480.87
344_R357_A1.6430.87
867_N873_A1.6420.87
781_V877_V1.6380.87
243_E336_N1.6310.87
456_V477_Y1.6310.87
95_L108_M1.6300.87
527_S530_D1.6280.87
474_D791_K1.6220.86
57_V80_L1.6150.86
661_E682_L1.6130.86
202_A205_A1.6120.86
856_V861_G1.6080.86
787_E791_K1.5960.86
164_E197_Y1.5870.85
406_A450_V1.5820.85
46_Q73_E1.5780.85
595_V599_I1.5760.85
761_N798_E1.5650.84
243_E247_W1.5580.84
420_L467_R1.5540.84
238_R246_V1.5470.84
28_F519_S1.5460.84
460_D477_Y1.5360.83
53_L193_E1.5360.83
686_A704_A1.5350.83
863_I877_V1.5240.83
724_M845_V1.5160.82
231_D234_M1.5130.82
46_Q71_M1.5130.82
257_I283_A1.5110.82
576_Q580_D1.5090.82
67_D195_K1.5050.82
414_L418_Q1.5030.82
46_Q50_A1.4990.82
62_T69_A1.4980.82
794_G797_A1.4960.82
65_R197_Y1.4930.81
457_V470_L1.4900.81
690_T708_R1.4890.81
267_V436_V1.4870.81
29_F33_A1.4840.81
430_M484_M1.4770.81
696_E699_P1.4700.80
456_V855_I1.4560.80
282_H335_H1.4550.80
741_L812_L1.4550.80
685_Q706_E1.4530.80
91_S95_L1.4490.79
518_M638_V1.4460.79
402_C447_P1.4390.79
558_L564_P1.4330.79
407_A795_A1.4310.79
110_E143_N1.4190.78
53_L104_A1.4180.78
620_R623_M1.4180.78
48_L51_Q1.4160.78
257_I305_A1.4140.78
223_L226_T1.4120.78
604_S607_K1.4090.77
364_A367_L1.4010.77
472_V484_M1.4010.77
110_E197_Y1.3990.77
123_K143_N1.3970.77
470_L650_S1.3920.77
146_H164_E1.3870.76
560_P563_H1.3860.76
256_C791_K1.3850.76
151_N165_T1.3730.76
125_W711_V1.3670.75
83_Q90_I1.3660.75
652_E655_R1.3660.75
177_V226_T1.3630.75
464_I472_V1.3630.75
24_K745_V1.3550.75
809_N878_T1.3520.74
748_A781_V1.3470.74
344_R371_L1.3460.74
83_Q116_A1.3440.74
430_M481_F1.3440.74
57_V60_V1.3420.74
77_V80_L1.3410.74
211_R243_E1.3340.73
147_L342_L1.3330.73
323_A359_R1.3320.73
51_Q195_K1.3290.73
26_K183_P1.3240.73
176_D182_L1.3230.73
681_V706_E1.3190.73
283_A309_A1.3170.72
71_M74_G1.3080.72
84_A87_G1.3060.72
781_V785_L1.3060.72
763_S802_D1.3020.72
123_K145_Q1.2980.71
114_S123_K1.2960.71
811_Q878_T1.2920.71
866_F876_R1.2900.71
682_L707_I1.2870.71
97_A803_A1.2800.70
46_Q74_G1.2760.70
84_A827_Q1.2740.70
157_V336_N1.2710.70
59_V107_L1.2680.69
556_G860_G1.2670.69
429_V459_F1.2640.69
26_K139_F1.2610.69
65_R194_G1.2580.69
45_A107_L1.2560.69
145_Q205_A1.2500.68
82_R89_H1.2480.68
793_A797_A1.2480.68
257_I306_L1.2450.68
494_L797_A1.2400.68
844_G847_L1.2390.68
111_L140_T1.2380.68
807_G814_V1.2340.67
164_E205_A1.2330.67
66_K69_A1.2320.67
518_M817_N1.2300.67
21_H24_K1.2290.67
440_A448_S1.2260.67
251_D261_T1.2190.66
146_H205_A1.2190.66
460_D472_V1.2160.66
86_R90_I1.2140.66
106_I131_L1.2140.66
498_V502_A1.2130.66
254_L337_L1.2130.66
673_H677_T1.2110.66
404_V443_Y1.2110.66
267_V305_A1.2090.66
861_G879_L1.2030.65
208_H451_A1.1970.65
641_A680_T1.1970.65
83_Q119_S1.1960.65
246_V336_N1.1960.65
269_A372_V1.1940.65
676_R726_R1.1930.65
432_Y455_N1.1930.65
78_L106_I1.1920.65
524_V711_V1.1890.64
352_R362_R1.1830.64
92_E116_A1.1780.64
57_V319_L1.1780.64
143_N164_E1.1770.64
707_I711_V1.1770.64
113_H116_A1.1740.63
472_V477_Y1.1680.63
59_V62_T1.1670.63
273_L512_T1.1630.63
71_M688_I1.1630.63
670_A845_V1.1620.63
194_G205_A1.1620.63
271_A670_A1.1600.62
59_V373_A1.1550.62
263_S305_A1.1550.62
27_V320_S1.1530.62
56_V78_L1.1430.61
404_V442_F1.1410.61
105_L137_D1.1360.61
29_F171_F1.1320.60
341_I372_V1.1310.60
602_L610_G1.1290.60
123_K208_H1.1210.60
690_T705_S1.1170.59
140_T812_L1.1160.59
456_V480_T1.1130.59
102_R741_L1.1100.59
324_E356_F1.1090.59
256_C852_C1.1080.59
128_I767_P1.1080.59
192_K549_V1.1040.59
51_Q193_E1.1020.58
611_L614_V1.1020.58
49_R54_D1.0970.58
751_M780_R1.0960.58
233_Q724_M1.0960.58
672_S724_M1.0950.58
318_T410_A1.0950.58
556_G563_H1.0920.58
253_I281_W1.0880.57
778_F856_V1.0870.57
449_V743_E1.0870.57
84_A89_H1.0850.57
39_W71_M1.0850.57
765_P768_L1.0840.57
582_G603_K1.0830.57
427_N459_F1.0810.57
787_E851_I1.0810.57
254_L470_L1.0810.57
269_A368_D1.0800.57
140_T144_V1.0800.57
327_A330_R1.0770.57
194_G197_Y1.0730.56
197_Y210_F1.0660.56
284_V468_G1.0640.56
752_L811_Q1.0630.56
332_A340_I1.0590.55
27_V140_T1.0550.55
283_A305_A1.0520.55
434_L490_V1.0490.55
85_Y110_E1.0490.55
30_G35_V1.0470.54
28_F195_K1.0470.54
611_L615_E1.0450.54
644_R724_M1.0400.54
793_A817_N1.0400.54
672_S722_L1.0370.54
288_T295_P1.0370.54
738_W772_H1.0360.54
72_L83_Q1.0330.53
28_F44_E1.0290.53
284_V808_E1.0280.53
59_V64_G1.0280.53
173_A865_A1.0270.53
282_H337_L1.0260.53
401_G443_Y1.0260.53
452_T492_G1.0250.53
145_Q197_Y1.0230.53
76_A254_L1.0230.53
341_I786_L1.0210.53
100_A106_I1.0190.52
196_V267_V1.0120.52
781_V787_E1.0110.52
67_D71_M1.0080.52
429_V437_V1.0060.51
257_I853_R1.0040.51
29_F339_K1.0030.51
213_G247_W1.0030.51
585_A792_Y1.0020.51
43_A71_M1.0010.51
784_N788_N0.9980.51
668_L674_D0.9970.51
225_R228_D0.9970.51
811_Q876_R0.9960.51
314_A484_M0.9950.51
27_V142_V0.9940.51
423_F476_Q0.9920.50
751_M779_E0.9910.50
121_H126_Q0.9900.50
805_V881_Q0.9900.50
863_I875_F0.9880.50
150_L674_D0.9860.50
70_A73_E0.9860.50
520_K524_V0.9830.50
238_R247_W0.9830.50
237_W835_R0.9790.49
57_V84_A0.9780.49
697_G801_I0.9770.49
65_R205_A0.9760.49
349_R352_R0.9740.49
772_H882_Q0.9730.49
862_T881_Q0.9730.49
802_D815_W0.9720.49
743_E747_S0.9720.49
764_L771_I0.9710.49
400_Q403_V0.9710.49
518_M634_F0.9700.49
690_T696_E0.9690.49
250_R260_N0.9680.49
197_Y202_A0.9670.49
559_Q562_T0.9670.49
22_R25_L0.9640.48
745_V823_P0.9640.48
338_G537_Q0.9610.48
172_D875_F0.9590.48
514_H634_F0.9550.48
238_R245_K0.9550.48
411_V829_I0.9540.48
303_L488_G0.9540.48
182_L221_L0.9520.48
63_H197_Y0.9510.47
558_L562_T0.9500.47
46_Q49_R0.9500.47
182_L195_K0.9490.47
464_I477_Y0.9440.47
700_H703_Q0.9430.47
413_T463_F0.9430.47
562_T566_G0.9420.47
68_T146_H0.9420.47
502_A505_A0.9370.46
338_G370_V0.9370.46
793_A821_L0.9360.46
123_K164_E0.9360.46
704_A707_I0.9360.46
61_E151_N0.9350.46
366_D549_V0.9350.46
698_S775_G0.9340.46
85_Y201_Q0.9340.46
339_K368_D0.9330.46
186_D656_M0.9320.46
556_G562_T0.9310.46
538_F542_T0.9300.46
65_R68_T0.9290.46
63_H143_N0.9270.46
761_N800_G0.9260.46
481_F484_M0.9250.46
821_L873_A0.9240.45
61_E197_Y0.9220.45
133_E266_L0.9220.45
756_L790_V0.9200.45
745_V766_E0.9190.45
615_E618_N0.9190.45
288_T627_Q0.9160.45
530_D537_Q0.9160.45
438_V821_L0.9150.45
725_A780_R0.9140.45
95_L185_D0.9140.45
609_Y613_V0.9110.45
197_Y214_N0.9100.44
30_G34_G0.9080.44
20_P236_A0.9080.44
31_A62_T0.9030.44
407_A414_L0.9030.44
140_T712_L0.9000.44
46_Q419_W0.9000.44
114_S143_N0.8980.44
134_A676_R0.8970.44
599_I613_V0.8970.44
226_T508_R0.8960.43
868_R874_C0.8960.43
229_R283_A0.8950.43
201_Q456_V0.8950.43
411_V415_I0.8950.43
648_T853_R0.8950.43
97_A462_F0.8920.43
163_R375_D0.8900.43
50_A142_V0.8900.43
815_W868_R0.8880.43
429_V476_Q0.8880.43
56_V176_D0.8870.43
833_F847_L0.8840.43
612_V635_T0.8820.42
58_G133_E0.8810.42
27_V638_V0.8800.42
191_L469_T0.8800.42
328_V631_L0.8800.42
266_L342_L0.8770.42
23_G30_G0.8770.42
316_T552_P0.8770.42
778_F859_H0.8770.42
684_G780_R0.8720.42
683_F708_R0.8710.42
156_G365_P0.8710.42
54_D104_A0.8700.42
248_H338_G0.8700.42
252_A280_V0.8680.41
612_V616_P0.8680.41
457_V482_A0.8660.41
690_T701_A0.8650.41
234_M237_W0.8640.41
478_L803_A0.8640.41
518_M787_E0.8630.41
228_D368_D0.8630.41
157_V247_W0.8610.41
696_E700_H0.8610.41
558_L563_H0.8610.41
788_N846_G0.8590.41
78_L170_F0.8590.41
751_M851_I0.8570.41
209_F589_T0.8570.41
32_C60_V0.8560.41
61_E68_T0.8560.41
559_Q563_H0.8560.41
478_L786_L0.8550.41
283_A469_T0.8550.41
586_G589_T0.8520.40
302_I510_Q0.8520.40
490_V641_A0.8520.40
359_R363_I0.8520.40
262_G374_L0.8520.40
147_L523_A0.8510.40
826_E865_A0.8510.40
739_L773_V0.8500.40
429_V484_M0.8490.40
157_V243_E0.8490.40
607_K821_L0.8480.40
557_K560_P0.8470.40
147_L457_V0.8460.40
134_A726_R0.8460.40
728_Q832_K0.8450.40
316_T494_L0.8440.40
89_H380_R0.8400.40
751_M783_I0.8400.40
24_K807_G0.8370.39
821_L824_G0.8360.39
44_E47_R0.8350.39
401_G429_V0.8340.39
271_A314_A0.8310.39
741_L810_L0.8300.39
252_A538_F0.8290.39
836_G873_A0.8280.39
478_L633_T0.8270.39
637_L640_N0.8270.39
782_L821_L0.8260.39
629_R633_T0.8260.39
252_A282_H0.8260.39
238_R249_T0.8250.38
221_L574_I0.8240.38
166_V711_V0.8220.38
550_L857_D0.8200.38
189_Q195_K0.8190.38
171_F177_V0.8190.38
640_N821_L0.8180.38
804_H813_D0.8140.38
95_L130_E0.8140.38
59_V80_L0.8130.38
666_A723_D0.8130.38
344_R492_G0.8110.38
486_T551_L0.8100.37
112_A141_T0.8100.37
554_D558_L0.8090.37
75_L147_L0.8090.37
90_I209_F0.8070.37
685_Q688_I0.8060.37
783_I852_C0.8060.37
510_Q732_F0.8050.37
515_L532_A0.8050.37
228_D670_A0.8040.37
243_E367_L0.8040.37
710_H725_A0.8040.37
99_L108_M0.8030.37
321_D367_L0.8020.37
411_V827_Q0.7970.37
410_A414_L0.7970.37
273_L276_R0.7960.36
98_A131_L0.7960.36
598_Q628_Q0.7960.36
840_S851_I0.7950.36
472_V478_L0.7950.36
69_A419_W0.7950.36
110_E151_N0.7950.36
196_V475_V0.7940.36
105_L139_F0.7940.36
470_L727_I0.7920.36
671_L714_T0.7900.36
182_L794_G0.7870.36
407_A747_S0.7840.36
734_L859_H0.7840.36
239_G471_A0.7840.36
432_Y451_A0.7830.36
305_A309_A0.7830.36
697_G700_H0.7830.36
257_I412_I0.7830.36
115_N120_R0.7820.36
55_I105_L0.7820.36
33_A574_I0.7810.35
125_W165_T0.7800.35
830_F833_F0.7790.35
61_E110_E0.7790.35
672_S677_T0.7780.35
832_K851_I0.7780.35
177_V469_T0.7770.35
216_I234_M0.7770.35
315_E335_H0.7770.35
85_Y197_Y0.7760.35
407_A410_A0.7750.35
416_A682_L0.7750.35
434_L484_M0.7750.35
820_G873_A0.7750.35
411_V414_L0.7730.35
479_L787_E0.7730.35
88_R116_A0.7710.35
637_L730_G0.7710.35
557_K562_T0.7710.35
479_L495_T0.7710.35
28_F189_Q0.7710.35
445_R449_V0.7700.35
820_G830_F0.7700.35
172_D271_A0.7680.35
432_Y655_R0.7670.35
48_L371_L0.7660.34
681_V768_L0.7660.34
105_L128_I0.7660.34
437_V638_V0.7650.34
553_D557_K0.7640.34
285_Y543_F0.7640.34
354_E372_V0.7640.34
741_L875_F0.7630.34
587_A616_P0.7630.34
477_Y484_M0.7620.34
156_G276_R0.7620.34
242_G831_D0.7620.34
661_E840_S0.7610.34
26_K532_A0.7610.34
58_G61_E0.7610.34
120_R601_P0.7610.34
578_S585_A0.7600.34
114_S771_I0.7600.34
256_C285_Y0.7600.34
475_V855_I0.7600.34
459_F484_M0.7600.34
61_E65_R0.7590.34
129_E479_L0.7590.34
61_E146_H0.7570.34
426_A429_V0.7560.34
486_T554_D0.7560.34
234_M336_N0.7560.34
459_F477_Y0.7550.34
243_E246_V0.7520.34
509_E661_E0.7520.34
307_R310_Q0.7520.34
102_R449_V0.7490.33
423_F663_I0.7490.33
93_F258_G0.7490.33
770_L880_P0.7480.33
285_Y294_L0.7470.33
688_I704_A0.7470.33
76_A105_L0.7470.33
627_Q851_I0.7460.33
599_I611_L0.7460.33
555_N564_P0.7460.33
233_Q279_S0.7450.33
44_E139_F0.7450.33
102_R407_A0.7440.33
260_N372_V0.7440.33
56_V642_L0.7440.33
146_H197_Y0.7430.33
574_I717_L0.7430.33
763_S800_G0.7430.33
512_T516_Y0.7420.33
229_R233_Q0.7410.33
229_R644_R0.7410.33
819_P853_R0.7400.33
759_P798_E0.7390.33
191_L440_A0.7380.33
637_L714_T0.7370.33
626_E671_L0.7370.33
733_N752_L0.7360.33
250_R276_R0.7360.33
791_K799_I0.7350.32
868_R871_G0.7350.32
774_D835_R0.7340.32
133_E418_Q0.7340.32
450_V782_L0.7340.32
414_L417_M0.7340.32
557_K565_Q0.7330.32
250_R409_C0.7330.32
450_V825_Q0.7330.32
817_N871_G0.7320.32
35_V68_T0.7320.32
563_H566_G0.7320.32
65_R164_E0.7320.32
456_V481_F0.7300.32
685_Q704_A0.7300.32
432_Y779_E0.7300.32
310_Q665_N0.7290.32
114_S197_Y0.7290.32
110_E209_F0.7290.32
348_R352_R0.7280.32
670_A728_Q0.7280.32
285_Y303_L0.7270.32
56_V270_A0.7250.32
649_A652_E0.7250.32
113_H123_K0.7250.32
113_H197_Y0.7240.32
658_S718_V0.7230.32
144_V845_V0.7220.32
51_Q863_I0.7220.32
558_L565_Q0.7210.32
160_I214_N0.7210.32
352_R358_D0.7210.32
86_R110_E0.7210.32
334_E492_G0.7210.32
61_E90_I0.7190.31
162_V209_F0.7190.31
40_A43_A0.7180.31
507_Y812_L0.7180.31
705_S709_Q0.7180.31
690_T859_H0.7170.31
664_R668_L0.7160.31
284_V337_L0.7160.31
461_L470_L0.7160.31
91_S116_A0.7150.31
45_A75_L0.7140.31
347_S355_T0.7130.31
492_G517_E0.7120.31
438_V490_V0.7120.31
47_R50_A0.7110.31
431_L585_A0.7110.31
248_H680_T0.7090.31
183_P476_Q0.7080.31
61_E145_Q0.7080.31
156_G166_V0.7080.31
486_T489_L0.7070.31
213_G238_R0.7060.31
27_V308_L0.7060.31
39_W391_F0.7050.31
196_V745_V0.7040.31
114_S662_Q0.7030.30
280_V479_L0.7020.30
106_I828_T0.7010.30
104_A742_E0.7000.30
709_Q770_L0.6990.30
449_V749_L0.6980.30
778_F801_I0.6950.30
452_T556_G0.6950.30
539_I590_D0.6940.30
414_L709_Q0.6930.30
464_I467_R0.6930.30
578_S581_K0.6920.30
784_N846_G0.6910.30
284_V319_L0.6910.30
467_R480_T0.6900.30
357_A492_G0.6900.30
249_T328_V0.6900.30
205_A214_N0.6900.30
798_E814_V0.6900.30
484_M713_N0.6890.30
102_R795_A0.6880.30
659_E720_N0.6880.30
347_S357_A0.6880.30
110_E194_G0.6880.30
344_R354_E0.6870.29
449_V485_L0.6870.29
283_A314_A0.6870.29
814_V860_G0.6860.29
27_V469_T0.6860.29
356_F655_R0.6820.29
409_C458_S0.6820.29
175_D183_P0.6810.29
110_E214_N0.6810.29
43_A267_V0.6800.29
169_P173_A0.6800.29
485_L612_V0.6800.29
73_E371_L0.6800.29
669_A842_V0.6800.29
783_I851_I0.6790.29
194_G210_F0.6780.29
33_A209_F0.6780.29
480_T674_D0.6770.29
484_M743_E0.6770.29
857_D862_T0.6770.29
107_L503_R0.6760.29
25_L30_G0.6760.29
90_I314_A0.6750.29
256_C343_G0.6740.29
63_H205_A0.6740.29
802_D813_D0.6740.29
653_Q814_V0.6740.29
57_V815_W0.6740.29
123_K197_Y0.6730.29
81_K119_S0.6730.29
424_D472_V0.6730.29
749_L794_G0.6720.29
670_A780_R0.6720.29
131_L287_E0.6720.29
180_V411_V0.6710.29
314_A543_F0.6710.29
61_E164_E0.6690.28
31_A183_P0.6690.28
58_G481_F0.6690.28
414_L801_I0.6690.28
682_L687_E0.6680.28
432_Y463_F0.6680.28
655_R658_S0.6680.28
111_L142_V0.6660.28
27_V79_P0.6660.28
508_R832_K0.6660.28
142_V189_Q0.6650.28
524_V539_I0.6650.28
110_E146_H0.6650.28
760_I783_I0.6650.28
633_T827_Q0.6640.28
389_R681_V0.6630.28
153_V548_Q0.6630.28
185_D704_A0.6610.28
333_R366_D0.6600.28
319_L819_P0.6590.28
497_G501_Q0.6580.28
133_E532_A0.6580.28
113_H143_N0.6580.28
347_S354_E0.6580.28
690_T703_Q0.6570.28
85_Y88_R0.6570.28
106_I485_L0.6570.28
128_I445_R0.6570.28
279_S338_G0.6560.28
58_G256_C0.6560.28
229_R366_D0.6550.28
40_A182_L0.6540.28
314_A724_M0.6540.28
128_I395_W0.6530.27
713_N769_T0.6520.27
673_H788_N0.6510.27
63_H209_F0.6500.27
746_G801_I0.6490.27
702_R705_S0.6490.27
687_E691_L0.6480.27
61_E80_L0.6480.27
177_V624_I0.6480.27
560_P565_Q0.6480.27
633_T825_Q0.6480.27
97_A100_A0.6470.27
33_A739_L0.6470.27
337_L452_T0.6470.27
113_H164_E0.6470.27
806_E811_Q0.6460.27
95_L273_L0.6460.27
252_A637_L0.6460.27
682_L852_C0.6460.27
622_L862_T0.6450.27
267_V558_L0.6450.27
378_P453_V0.6440.27
713_N751_M0.6440.27
251_D681_V0.6430.27
516_Y851_I0.6430.27
412_I415_I0.6430.27
344_R352_R0.6430.27
261_T439_V0.6420.27
598_Q792_Y0.6420.27
748_A783_I0.6410.27
137_D482_A0.6410.27
724_M850_A0.6410.27
26_K169_P0.6410.27
650_S653_Q0.6400.27
85_Y196_V0.6380.27
59_V110_E0.6380.27
469_T599_I0.6380.27
63_H146_H0.6380.27
641_A666_A0.6380.27
162_V204_R0.6370.27
27_V43_A0.6370.27
586_G591_T0.6370.27
342_L381_T0.6360.26
331_Y875_F0.6350.26
333_R853_R0.6350.26
553_D642_L0.6350.26
48_L195_K0.6350.26
143_N210_F0.6340.26
253_I364_A0.6340.26
160_I631_L0.6340.26
431_L479_L0.6340.26
197_Y208_H0.6330.26
379_A415_I0.6330.26
347_S727_I0.6330.26
229_R358_D0.6320.26
199_A423_F0.6300.26
633_T698_S0.6290.26
177_V583_L0.6290.26
399_I792_Y0.6290.26
327_A582_G0.6290.26
251_D331_Y0.6290.26
98_A140_T0.6290.26
590_D594_G0.6290.26
681_V875_F0.6280.26
441_L449_V0.6280.26
147_L344_R0.6270.26
460_D677_T0.6270.26
659_E665_N0.6270.26
56_V251_D0.6250.26
161_Q743_E0.6240.26
706_E724_M0.6240.26
91_S472_V0.6240.26
250_R368_D0.6230.26
110_E145_Q0.6230.26
652_E821_L0.6220.26
85_Y362_R0.6220.26
415_I618_N0.6210.26
297_K479_L0.6200.26
287_E299_R0.6200.26
448_S501_Q0.6190.26
65_R110_E0.6180.25
816_D873_A0.6180.25
734_L795_A0.6180.25
41_M136_I0.6180.25
486_T864_T0.6180.25
28_F193_E0.6180.25
809_N862_T0.6180.25
122_P593_P0.6180.25
764_L829_I0.6170.25
164_E210_F0.6170.25
63_H110_E0.6160.25
304_S369_Q0.6160.25
68_T145_Q0.6160.25
273_L508_R0.6150.25
498_V656_M0.6150.25
91_S462_F0.6150.25
580_D814_V0.6140.25
507_Y510_Q0.6140.25
70_A853_R0.6130.25
329_V363_I0.6120.25
115_N130_E0.6120.25
32_C488_G0.6120.25
105_L802_D0.6110.25
661_E736_K0.6110.25
644_R880_P0.6100.25
473_S582_G0.6100.25
664_R858_V0.6100.25
717_L774_D0.6100.25
634_F724_M0.6090.25
395_W399_I0.6080.25
800_G817_N0.6080.25
55_I414_L0.6070.25
68_T164_E0.6070.25
424_D498_V0.6070.25
626_E814_V0.6070.25
215_L668_L0.6060.25
182_L191_L0.6050.25
413_T461_L0.6050.25
106_I437_V0.6040.25
133_E173_A0.6040.25
250_R728_Q0.6040.25
765_P829_I0.6040.25
595_V598_Q0.6040.25
325_E356_F0.6030.25
429_V472_V0.6030.25
599_I741_L0.6020.25
144_V814_V0.6020.25
561_L565_Q0.6010.25
233_Q787_E0.6010.25
429_V478_L0.5990.24
792_Y835_R0.5990.24
84_A462_F0.5980.24
441_L491_I0.5980.24
336_N632_E0.5980.24
420_L811_Q0.5980.24
718_V747_S0.5980.24
370_V487_V0.5980.24
57_V107_L0.5970.24
237_W247_W0.5970.24
84_A482_A0.5970.24
93_F356_F0.5970.24
197_Y209_F0.5970.24
172_D522_L0.5960.24
446_W732_F0.5960.24
157_V249_T0.5950.24
217_A234_M0.5950.24
433_L634_F0.5950.24
644_R845_V0.5950.24
247_W835_R0.5950.24
21_H701_A0.5940.24
108_M621_Q0.5940.24
83_Q403_V0.5940.24
184_P519_S0.5940.24
62_T72_L0.5940.24
598_Q603_K0.5930.24
331_Y508_R0.5930.24
345_P357_A0.5920.24
479_L810_L0.5920.24
748_A795_A0.5920.24
114_S205_A0.5920.24
116_A129_E0.5910.24
403_V478_L0.5900.24
95_L104_A0.5900.24
393_D401_G0.5900.24
436_V748_A0.5900.24
95_L653_Q0.5890.24
230_V234_M0.5890.24
278_G314_A0.5880.24
276_R373_A0.5880.24
71_M798_E0.5880.24
414_L808_E0.5880.24
549_V727_I0.5880.24
45_A628_Q0.5880.24
287_E481_F0.5880.24
544_H805_V0.5880.24
862_T877_V0.5870.24
773_V781_V0.5870.24
125_W188_R0.5860.24
328_V368_D0.5860.24
142_V775_G0.5860.24
508_R660_R0.5860.24
425_A700_H0.5850.24
166_V745_V0.5850.24
304_S405_A0.5830.24
480_T494_L0.5830.24
362_R460_D0.5830.24
136_I720_N0.5810.23
786_L880_P0.5810.23
205_A209_F0.5800.23
603_K606_E0.5790.23
271_A450_V0.5790.23
39_W585_A0.5780.23
95_L862_T0.5780.23
371_L878_T0.5780.23
44_E48_L0.5770.23
165_T626_E0.5770.23
518_M637_L0.5770.23
131_L426_A0.5760.23
68_T205_A0.5750.23
573_A584_P0.5750.23
832_K835_R0.5750.23
110_E113_H0.5750.23
312_L440_A0.5750.23
63_H68_T0.5740.23
364_A374_L0.5740.23
27_V464_I0.5730.23
411_V555_N0.5730.23
39_W160_I0.5730.23
566_G814_V0.5730.23
35_V205_A0.5720.23
57_V631_L0.5720.23
337_L516_Y0.5720.23
344_R851_I0.5720.23
788_N848_G0.5720.23
480_T668_L0.5720.23
764_L768_L0.5700.23
40_A228_D0.5700.23
230_V787_E0.5700.23
718_V792_Y0.5690.23
781_V859_H0.5690.23
446_W630_L0.5690.23
361_A438_V0.5690.23
626_E737_E0.5680.23
431_L483_V0.5680.23
512_T740_T0.5680.23
633_T665_N0.5680.23
116_A316_T0.5670.23
235_R543_F0.5670.23
669_A713_N0.5660.23
685_Q703_Q0.5660.23
804_H811_Q0.5660.23
61_E143_N0.5660.23
45_A520_K0.5660.23
101_R104_A0.5650.23
412_I452_T0.5650.23
63_H123_K0.5650.23
241_P425_A0.5650.23
444_G670_A0.5650.23
223_L774_D0.5640.23
110_E114_S0.5640.23
744_V748_A0.5640.23
483_V677_T0.5640.23
147_L779_E0.5640.23
352_R450_V0.5640.23
144_V766_E0.5640.23
49_R116_A0.5630.23
601_P867_N0.5630.23
274_A745_V0.5630.23
546_R766_E0.5620.23
735_K877_V0.5620.23
540_A548_Q0.5620.23
309_A663_I0.5610.22
207_E864_T0.5610.22
484_M715_T0.5610.22
392_K453_V0.5590.22
555_N558_L0.5580.22
804_H878_T0.5580.22
48_L671_L0.5570.22
810_L862_T0.5570.22
341_I681_V0.5570.22
257_I316_T0.5570.22
184_P255_L0.5560.22
488_G792_Y0.5560.22
227_A847_L0.5560.22
682_L842_V0.5550.22
448_S493_N0.5550.22
201_Q368_D0.5550.22
254_L803_A0.5540.22
661_E855_I0.5540.22
633_T671_L0.5530.22
257_I404_V0.5530.22
49_R75_L0.5530.22
179_L329_V0.5530.22
100_A144_V0.5530.22
257_I364_A0.5530.22
416_A489_L0.5520.22
741_L771_I0.5520.22
284_V811_Q0.5510.22
560_P564_P0.5500.22
35_V61_E0.5500.22
40_A661_E0.5500.22
30_G65_R0.5500.22
67_D140_T0.5490.22
368_D372_V0.5490.22
288_T294_L0.5490.22
505_A670_A0.5490.22
48_L189_Q0.5480.22
405_A799_I0.5480.22
287_E434_L0.5470.22
373_A443_Y0.5470.22
58_G740_T0.5460.22
78_L403_V0.5460.22
25_L34_G0.5460.22
470_L519_S0.5460.22
664_R674_D0.5450.22
793_A826_E0.5450.22
79_P264_E0.5440.22
201_Q208_H0.5440.22
407_A702_R0.5440.22
267_V488_G0.5440.22
202_A592_L0.5430.22
269_A339_K0.5430.22
283_A306_L0.5430.22
53_L856_V0.5420.22
97_A347_S0.5420.22
170_F363_I0.5420.22
723_D854_A0.5410.21
73_E102_R0.5410.21
250_R638_V0.5410.21
277_L832_K0.5410.21
37_K143_N0.5410.21
108_M221_L0.5400.21
129_E807_G0.5400.21
697_G767_P0.5400.21
680_T708_R0.5400.21
816_D872_G0.5400.21
361_A431_L0.5400.21
60_V450_V0.5400.21
33_A781_V0.5400.21
35_V179_L0.5390.21
163_R714_T0.5390.21
513_R863_I0.5390.21
68_T110_E0.5380.21
454_I746_G0.5380.21
461_L641_A0.5380.21
427_N477_Y0.5370.21
130_E577_W0.5370.21
445_R713_N0.5360.21
35_V65_R0.5360.21
151_N469_T0.5360.21
122_P423_F0.5360.21
85_Y164_E0.5360.21
128_I768_L0.5350.21
56_V59_V0.5350.21
137_D742_E0.5350.21
253_I264_E0.5340.21
126_Q209_F0.5340.21
191_L202_A0.5340.21
801_I805_V0.5340.21
656_M859_H0.5340.21
303_L356_F0.5340.21
682_L751_M0.5330.21
606_E609_Y0.5330.21
377_P482_A0.5330.21
319_L327_A0.5330.21
666_A826_E0.5320.21
24_K737_E0.5310.21
440_A453_V0.5310.21
412_I416_A0.5310.21
830_F872_G0.5300.21
40_A859_H0.5300.21
469_T472_V0.5300.21
372_V814_V0.5300.21
27_V417_M0.5300.21
35_V194_G0.5300.21
130_E738_W0.5300.21
851_I865_A0.5290.21
666_A713_N0.5290.21
186_D734_L0.5290.21
513_R517_E0.5280.21
234_M252_A0.5270.21
399_I520_K0.5260.21
415_I881_Q0.5250.21
200_G203_E0.5250.21
484_M680_T0.5240.21
698_S828_T0.5240.21
273_L353_R0.5240.21
286_V343_G0.5240.21
241_P283_A0.5240.21
771_I882_Q0.5230.21
72_L173_A0.5230.21
454_I464_I0.5230.21
577_W586_G0.5230.21
206_I458_S0.5230.21
724_M851_I0.5230.21
82_R142_V0.5220.21
453_V485_L0.5220.21
68_T143_N0.5220.21
470_L697_G0.5220.21
499_R832_K0.5210.20
199_A203_E0.5210.20
105_L491_I0.5210.20
321_D431_L0.5210.20
170_F175_D0.5200.20
110_E162_V0.5200.20
335_H356_F0.5200.20
147_L188_R0.5200.20
347_S356_F0.5200.20
314_A534_T0.5190.20
243_E280_V0.5190.20
90_I197_Y0.5190.20
183_P441_L0.5180.20
162_V197_Y0.5180.20
516_Y776_P0.5180.20
157_V166_V0.5180.20
110_E123_K0.5170.20
354_E362_R0.5170.20
805_V808_E0.5170.20
196_V356_F0.5170.20
677_T680_T0.5160.20
175_D264_E0.5160.20
238_R243_E0.5150.20
579_F582_G0.5150.20
314_A436_V0.5140.20
723_D726_R0.5130.20
152_D721_L0.5130.20
26_K212_K0.5130.20
288_T329_V0.5120.20
271_A275_S0.5120.20
432_Y538_F0.5120.20
480_T669_A0.5120.20
33_A80_L0.5110.20
28_F630_L0.5110.20
599_I602_L0.5110.20
63_H194_G0.5100.20
348_R361_A0.5090.20
57_V690_T0.5080.20
99_L617_G0.5080.20
258_G343_G0.5080.20
558_L561_L0.5070.20
656_M661_E0.5060.20
69_A199_A0.5060.20
736_K772_H0.5060.20
447_P776_P0.5060.20
285_Y635_T0.5050.20
323_A856_V0.5050.20
150_L664_R0.5050.20
461_L502_A0.5050.20
234_M538_F0.5050.20
144_V480_T0.5050.20
147_L319_L0.5040.20
673_H784_N0.5030.20
267_V300_R0.5030.20
285_Y302_I0.5020.20
164_E194_G0.5020.20
640_N663_I0.5020.20
63_H210_F0.5020.20
415_I560_P0.5020.20
685_Q862_T0.5020.20
250_R370_V0.5020.20
99_L489_L0.5020.20
348_R351_W0.5020.20
77_V199_A0.5010.20
48_L199_A0.5010.20
309_A316_T0.5010.20
81_K99_L0.5010.20
226_T659_E0.5010.20
252_A337_L0.5010.20
539_I681_V0.5010.20
488_G510_Q0.5000.20
220_E272_R0.5000.20
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4i5sA 2 0.4206 100 0.859 Contact Map
4gczA 2 0.3993 100 0.87 Contact Map
3jz3A 2 0.1779 100 0.87 Contact Map
4q20A 2 0.255 100 0.871 Contact Map
2c2aA 2 0.2595 100 0.872 Contact Map
3a0rA 2 0.3647 100 0.872 Contact Map
4mpcA 2 0.3367 100 0.873 Contact Map
3d36A 2 0.2461 100 0.874 Contact Map
4e01A 3 0.3143 100 0.875 Contact Map
4ctiA 2 0.255 100 0.877 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0204 seconds.