RNE - ECOLI - GREMLIN Contacts

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RNE - Ribonuclease E

UniProt:	P21513	Sequences: MKRMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYKGKITRIEPSLEAAFVDYGAERHGFLPLKEIAREYFPANYSAHGRPNIKDVLREGQEVIVQIDKEERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIEGDDRTELKEALASLELPEGMGLIVRTAGVGKSAEALQWDLSFRLKHWEAIKKAAESRPAPFLIHQESNVIVRAFRDYLRQDIGEILIDNPKVLELARQHIAALGRPDFSSKIKLYTGEIPLFSHYQIESQIESAFQREVRLPSGGSIVIDSTEALTAIDINSARATRGGDIEETAFNTNLEAADEIARQLRLRDLGGLIVIDFIDMTPVRHQRAVENRLREAVRQDRARIQISHISRFGLLEMSRQRLSPSLGESSHHVCPRCSGTGTVRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIASYLLNEKRSAVNAIETRQDGVRCVIVPNDQMETPHYHVLRVRKGEETPTLSYMLPKLHEEAMALPSEEEFAERKRPEQPALATFAMPDVPPAPTPAEPAAPVVAPAPKAAPATPAAPAQPGLLSRFFGALKALFSGGEETKPTEQPAPKAEAKPERQQDRRKPRQNNRRDRNERRDTRSERTEGSDNREENRRNRRQAQQQTAETRESRQQAEVTEKARTADEQQAPRRERSRRRNDDKRQAQQEAKALNVEEQSVQETEQEERVRPVQPRRKQRQLNQKVRYEQSVAEEAVVAPVVEETVAAEPIVQEAPAPRTELVKVPLPVVAQTAPEQQEENNADNRDNGGMPRRSRRSPRHLRVSGQRRRRYRDERYPTQSPMPLTVACASPELASGKVWIRYPIVRPQDVQVEEQREQEEVHVQPMVTEVPVAAAIEPVVSAPVVEEVAGVVEAPVQVAEPQPEVVETTHPEVIAAAVTEQPQVITESDVAVAQEVAEQAEPVVEPQEETADIEEVVETAEVVVAEPEVVAQPAAPVVAEVAAEVETVAAVEPEVTVEHNHATAPMTRAPAPEYVPEAPRHSDWQRPTFAFEGKGAAGGHTATHHASAAPARPQPVE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10859
Length:	1061 (962)
Sequences:	747 (658)
Seq/√Len:	21.2

ECOLI - RNE

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
526_Q	530_A	9.220	1.00
720_R	723_R	5.407	1.00
49_I	94_L	5.042	1.00
527_P	530_A	4.893	1.00
639_N	642_N	4.795	1.00
694_A	697_L	4.424	1.00
648_Q	651_A	4.368	1.00
719_R	722_Q	4.014	1.00
328_D	362_R	3.900	1.00
527_P	532_F	3.880	1.00
78_F	119_F	3.729	1.00
524_P	527_P	3.595	1.00
680_S	684_N	3.516	1.00
525_E	530_A	3.465	1.00
571_L	574_F	3.431	1.00
688_R	691_Q	3.412	1.00
328_D	366_A	3.399	1.00
420_S	447_I	3.357	1.00
527_P	531_T	3.324	1.00
672_Q	675_P	3.219	1.00
645_Q	648_Q	3.180	1.00
651_A	654_R	3.133	1.00
279_F	385_L	3.111	1.00
104_I	377_S	3.032	0.99
682_R	688_R	3.012	0.99
801_S	804_H	2.970	0.99
569_G	573_R	2.967	0.99
136_A	165_G	2.891	0.99
705_Q	708_E	2.859	0.99
642_N	645_Q	2.793	0.99
691_Q	694_A	2.783	0.99
711_E	714_R	2.748	0.99
615_N	618_D	2.744	0.99
670_D	673_Q	2.712	0.99
526_Q	531_T	2.688	0.99
442_I	479_M	2.652	0.99
660_A	663_T	2.633	0.98
478_Q	506_H	2.620	0.98
741_V	744_V	2.594	0.98
401_H	410_T	2.579	0.98
797_R	800_R	2.557	0.98
73_I	94_L	2.544	0.98
442_I	476_N	2.542	0.98
616_R	619_R	2.527	0.98
676_R	679_R	2.509	0.98
529_L	532_F	2.506	0.98
186_F	246_A	2.501	0.98
700_E	703_S	2.477	0.98
725_L	728_K	2.461	0.98
729_V	732_E	2.455	0.98
719_R	725_L	2.416	0.97
657_R	660_A	2.415	0.97
738_E	741_V	2.348	0.97
803_R	806_R	2.303	0.96
570_L	573_R	2.286	0.96
619_R	622_R	2.267	0.96
524_P	531_T	2.246	0.96
439_V	493_E	2.232	0.96
646_A	649_Q	2.229	0.96
708_E	711_E	2.202	0.95
799_R	806_R	2.196	0.95
524_P	530_A	2.195	0.95
641_R	644_R	2.192	0.95
719_R	729_V	2.189	0.95
586_E	589_K	2.174	0.95
261_G	268_H	2.164	0.95
674_A	677_R	2.157	0.95
397_G	412_T	2.152	0.95
267_S	401_H	2.150	0.95
574_F	578_L	2.141	0.94
525_E	529_L	2.122	0.94
627_S	630_T	2.086	0.94
215_V	243_H	2.083	0.94
70_L	290_S	2.079	0.93
173_V	300_T	2.078	0.93
104_I	175_K	2.053	0.93
794_M	804_H	2.049	0.93
426_L	484_Y	2.048	0.93
682_R	685_D	2.046	0.93
669_A	672_Q	2.045	0.93
243_H	249_R	2.045	0.93
697_L	700_E	2.040	0.93
125_S	249_R	2.035	0.93
804_H	807_V	2.029	0.93
720_R	726_N	2.028	0.93
675_P	683_R	2.023	0.93
722_Q	730_R	2.022	0.93
669_A	675_P	2.008	0.92
34_H	107_E	2.003	0.92
190_H	243_H	2.000	0.92
802_P	807_V	1.998	0.92
525_E	531_T	1.997	0.92
32_P	173_V	1.994	0.92
633_S	636_R	1.992	0.92
726_N	729_V	1.985	0.92
727_Q	730_R	1.970	0.91
612_R	615_N	1.968	0.91
295_S	301_A	1.967	0.91
27_L	279_F	1.964	0.91
697_L	703_S	1.958	0.91
79_P	95_R	1.953	0.91
635_N	638_E	1.949	0.91
798_S	804_H	1.936	0.91
606_Q	611_P	1.920	0.90
631_E	634_D	1.906	0.90
714_R	717_Q	1.903	0.90
573_R	582_F	1.898	0.90
922_V	933_D	1.889	0.90
725_L	729_V	1.887	0.90
667_R	670_D	1.887	0.90
614_N	618_D	1.880	0.89
911_E	917_V	1.878	0.89
941_A	944_A	1.878	0.89
503_P	506_H	1.876	0.89
799_R	804_H	1.864	0.89
722_Q	725_L	1.858	0.89
186_F	247_L	1.852	0.89
610_K	613_Q	1.849	0.89
320_F	355_H	1.839	0.88
639_N	643_R	1.838	0.88
526_Q	529_L	1.831	0.88
640_R	643_R	1.828	0.88
19_V	22_Q	1.821	0.88
717_Q	720_R	1.818	0.88
602_P	605_Q	1.812	0.88
801_S	808_S	1.812	0.88
679_R	682_R	1.808	0.87
626_R	629_R	1.796	0.87
914_H	931_E	1.787	0.87
601_K	604_R	1.778	0.87
797_R	801_S	1.775	0.86
921_A	924_E	1.770	0.86
802_P	805_L	1.764	0.86
415_D	432_L	1.753	0.86
722_Q	727_Q	1.749	0.86
443_V	449_S	1.747	0.86
946_P	955_A	1.743	0.85
186_F	243_H	1.741	0.85
732_E	735_V	1.740	0.85
625_T	628_E	1.739	0.85
506_H	511_A	1.738	0.85
186_F	190_H	1.721	0.85
522_K	526_Q	1.718	0.85
125_S	175_K	1.711	0.84
186_F	215_V	1.708	0.84
34_H	125_S	1.696	0.84
401_H	415_D	1.693	0.84
224_Q	387_M	1.692	0.84
579_K	582_F	1.690	0.84
607_D	610_K	1.690	0.84
974_V	980_P	1.687	0.83
672_Q	676_R	1.683	0.83
962_E	965_E	1.678	0.83
32_P	355_H	1.671	0.83
125_S	243_H	1.669	0.83
685_D	688_R	1.669	0.83
911_E	916_E	1.656	0.82
794_M	797_R	1.655	0.82
655_E	659_Q	1.650	0.82
621_E	624_D	1.647	0.82
609_R	612_R	1.632	0.81
719_R	730_R	1.631	0.81
654_R	657_R	1.627	0.81
668_T	672_Q	1.627	0.81
811_R	814_R	1.620	0.81
723_R	726_N	1.618	0.81
166_L	279_F	1.599	0.80
939_E	979_A	1.590	0.80
735_V	738_E	1.589	0.80
263_I	474_V	1.588	0.79
18_L	139_I	1.587	0.79
45_K	426_L	1.587	0.79
600_A	604_R	1.587	0.79
577_A	581_L	1.583	0.79
797_R	803_R	1.578	0.79
244_I	477_D	1.576	0.79
213_V	304_I	1.575	0.79
273_S	428_E	1.573	0.79
70_L	309_A	1.569	0.79
415_D	449_S	1.568	0.79
186_F	189_K	1.565	0.78
267_S	466_Q	1.558	0.78
578_L	582_F	1.556	0.78
105_D	307_A	1.554	0.78
962_E	967_V	1.552	0.78
593_Q	596_P	1.549	0.78
89_N	168_V	1.546	0.78
358_A	361_N	1.543	0.77
618_D	621_E	1.540	0.77
673_Q	676_R	1.538	0.77
723_R	727_Q	1.537	0.77
706_E	709_Q	1.536	0.77
168_V	304_I	1.529	0.77
155_L	195_K	1.527	0.77
229_I	435_N	1.524	0.77
613_Q	616_R	1.521	0.76
795_P	807_V	1.520	0.76
277_S	361_N	1.515	0.76
311_R	511_A	1.501	0.75
643_R	646_A	1.496	0.75
249_R	261_G	1.495	0.75
14_L	94_L	1.488	0.75
834_S	840_G	1.483	0.75
795_P	802_P	1.474	0.74
449_S	466_Q	1.472	0.74
34_H	249_R	1.468	0.74
32_P	300_T	1.460	0.73
809_G	814_R	1.459	0.73
190_H	218_F	1.452	0.73
49_I	224_Q	1.449	0.73
233_N	399_S	1.445	0.73
385_L	520_E	1.442	0.72
201_R	205_F	1.439	0.72
799_R	802_P	1.439	0.72
633_S	642_N	1.437	0.72
649_Q	653_T	1.434	0.72
241_R	245_A	1.433	0.72
725_L	731_Y	1.426	0.72
60_Y	229_I	1.424	0.71
801_S	809_G	1.422	0.71
929_I	932_S	1.421	0.71
569_G	574_F	1.420	0.71
798_S	801_S	1.418	0.71
6_I	378_H	1.415	0.71
632_G	635_N	1.415	0.71
37_K	428_E	1.412	0.71
637_E	640_R	1.409	0.71
25_Y	37_K	1.405	0.70
215_V	367_V	1.402	0.70
542_T	545_E	1.398	0.70
11_Q	34_H	1.388	0.69
11_Q	49_I	1.385	0.69
10_Q	500_Y	1.375	0.69
320_F	501_M	1.375	0.69
208_H	231_I	1.374	0.69
277_S	300_T	1.373	0.69
190_H	249_R	1.370	0.68
972_E	978_A	1.366	0.68
895_V	898_A	1.365	0.68
608_R	618_D	1.365	0.68
922_V	925_Q	1.363	0.68
614_N	620_N	1.363	0.68
644_R	648_Q	1.361	0.68
33_G	435_N	1.360	0.68
10_Q	14_L	1.358	0.68
718_P	722_Q	1.358	0.68
246_A	378_H	1.357	0.68
254_S	385_L	1.356	0.68
31_S	351_T	1.356	0.68
797_R	804_H	1.354	0.67
401_H	440_H	1.348	0.67
208_H	355_H	1.347	0.67
694_A	703_S	1.346	0.67
442_I	577_A	1.345	0.67
226_I	267_S	1.343	0.67
6_I	387_M	1.342	0.67
343_I	443_V	1.339	0.67
916_E	919_A	1.339	0.67
683_R	689_Q	1.338	0.66
719_R	728_K	1.337	0.66
215_V	308_R	1.334	0.66
76_E	442_I	1.333	0.66
309_A	535_P	1.333	0.66
49_I	376_I	1.332	0.66
16_V	28_D	1.331	0.66
796_R	800_R	1.323	0.66
374_I	437_Q	1.323	0.66
25_Y	428_E	1.322	0.66
242_Q	246_A	1.322	0.66
31_S	56_A	1.321	0.65
925_Q	941_A	1.317	0.65
249_R	268_H	1.312	0.65
795_P	800_R	1.311	0.65
629_R	632_G	1.308	0.65
895_V	905_P	1.306	0.65
843_W	847_P	1.301	0.64
403_V	408_S	1.294	0.64
935_A	959_E	1.293	0.64
711_E	717_Q	1.293	0.64
152_K	189_K	1.289	0.64
669_A	674_A	1.287	0.63
560_A	563_A	1.286	0.63
589_K	592_E	1.284	0.63
416_N	493_E	1.280	0.63
794_M	799_R	1.278	0.63
914_H	923_T	1.273	0.63
687_K	691_Q	1.272	0.62
89_N	351_T	1.270	0.62
87_R	486_V	1.269	0.62
794_M	801_S	1.269	0.62
905_P	908_E	1.262	0.62
783_E	897_E	1.261	0.62
925_Q	934_V	1.260	0.62
368_R	484_Y	1.259	0.62
933_D	936_V	1.259	0.62
175_K	300_T	1.259	0.62
608_R	611_P	1.258	0.62
417_E	436_T	1.256	0.61
805_L	808_S	1.255	0.61
959_E	963_T	1.253	0.61
680_S	683_R	1.250	0.61
897_E	971_P	1.248	0.61
753_P	756_Q	1.246	0.61
18_L	213_V	1.245	0.61
139_I	252_F	1.244	0.61
18_L	244_I	1.243	0.61
182_W	308_R	1.231	0.60
681_R	687_K	1.229	0.60
722_Q	731_Y	1.226	0.60
246_A	403_V	1.225	0.59
267_S	486_V	1.224	0.59
243_H	300_T	1.224	0.59
125_S	261_G	1.221	0.59
643_R	649_Q	1.220	0.59
32_P	527_P	1.218	0.59
573_R	578_L	1.217	0.59
14_L	263_I	1.216	0.59
207_I	231_I	1.216	0.59
640_R	645_Q	1.215	0.59
525_E	532_F	1.215	0.59
437_Q	498_L	1.211	0.59
798_S	802_P	1.211	0.59
125_S	268_H	1.211	0.59
258_L	461_A	1.208	0.58
397_G	403_V	1.208	0.58
973_V	979_A	1.206	0.58
521_R	524_P	1.200	0.58
146_D	420_S	1.198	0.58
125_S	300_T	1.198	0.58
690_A	693_E	1.197	0.58
726_N	732_E	1.195	0.58
186_F	308_R	1.195	0.58
526_Q	532_F	1.192	0.57
127_L	228_E	1.190	0.57
458_A	476_N	1.189	0.57
246_A	416_N	1.187	0.57
681_R	684_N	1.182	0.57
218_F	256_I	1.176	0.56
800_R	803_R	1.173	0.56
182_W	247_L	1.172	0.56
721_K	724_Q	1.172	0.56
243_H	268_H	1.170	0.56
611_P	615_N	1.169	0.56
601_K	605_Q	1.168	0.56
6_I	25_Y	1.168	0.56
186_F	461_A	1.160	0.55
958_E	967_V	1.160	0.55
792_G	807_V	1.160	0.55
684_N	690_A	1.159	0.55
573_R	581_L	1.158	0.55
725_L	730_R	1.156	0.55
484_Y	579_K	1.156	0.55
925_Q	929_I	1.154	0.55
155_L	385_L	1.154	0.55
880_I	951_Q	1.154	0.55
34_H	243_H	1.152	0.55
574_F	577_A	1.152	0.55
222_L	304_I	1.151	0.55
438_E	470_R	1.146	0.54
119_F	803_R	1.146	0.54
962_E	972_E	1.146	0.54
175_K	249_R	1.145	0.54
234_P	238_E	1.143	0.54
34_H	300_T	1.143	0.54
79_P	82_Y	1.143	0.54
810_Q	813_R	1.143	0.54
617_R	620_N	1.140	0.54
125_S	190_H	1.140	0.54
870_M	879_A	1.137	0.54
139_I	244_I	1.137	0.54
186_F	208_H	1.136	0.54
163_G	251_D	1.134	0.53
301_A	309_A	1.132	0.53
440_H	491_K	1.132	0.53
224_Q	255_K	1.126	0.53
229_I	368_R	1.125	0.53
679_R	683_R	1.124	0.53
378_H	428_E	1.119	0.53
229_I	339_L	1.119	0.53
932_S	935_A	1.118	0.52
649_Q	652_E	1.117	0.52
240_A	328_D	1.117	0.52
923_T	927_Q	1.116	0.52
724_Q	730_R	1.115	0.52
961_V	965_E	1.114	0.52
31_S	352_P	1.112	0.52
705_Q	711_E	1.112	0.52
603_E	606_Q	1.112	0.52
572_S	576_G	1.112	0.52
798_S	809_G	1.110	0.52
622_R	625_T	1.109	0.52
440_H	489_V	1.109	0.52
105_D	423_I	1.108	0.52
165_G	378_H	1.105	0.52
39_A	91_K	1.104	0.52
352_P	364_R	1.100	0.51
62_A	313_G	1.096	0.51
367_V	376_I	1.094	0.51
675_P	685_D	1.091	0.51
214_I	419_L	1.091	0.51
871_V	874_V	1.091	0.51
804_H	809_G	1.088	0.50
951_Q	963_T	1.086	0.50
320_F	330_I	1.083	0.50
623_R	627_S	1.083	0.50
416_N	501_M	1.082	0.50
70_L	222_L	1.078	0.50
6_I	152_K	1.077	0.50
917_V	926_P	1.076	0.50
91_K	395_S	1.075	0.50
928_V	944_A	1.073	0.49
628_E	631_E	1.072	0.49
343_I	438_E	1.071	0.49
33_G	251_D	1.069	0.49
399_S	465_R	1.067	0.49
277_S	435_N	1.066	0.49
653_T	659_Q	1.064	0.49
875_P	924_E	1.060	0.49
49_I	400_S	1.059	0.48
34_H	79_P	1.057	0.48
570_L	574_F	1.056	0.48
643_R	648_Q	1.053	0.48
235_K	354_R	1.053	0.48
604_R	608_R	1.053	0.48
295_S	432_L	1.052	0.48
965_E	968_V	1.052	0.48
802_P	806_R	1.050	0.48
816_R	819_R	1.050	0.48
369_Q	439_V	1.048	0.48
416_N	497_T	1.048	0.48
432_L	440_H	1.048	0.48
89_N	304_I	1.045	0.48
168_V	222_L	1.045	0.48
34_H	268_H	1.045	0.48
636_R	642_N	1.042	0.47
32_P	399_S	1.042	0.47
611_P	630_T	1.041	0.47
190_H	208_H	1.041	0.47
196_K	374_I	1.040	0.47
243_H	261_G	1.040	0.47
125_S	367_V	1.040	0.47
194_I	530_A	1.039	0.47
136_A	212_N	1.038	0.47
913_T	919_A	1.037	0.47
378_H	534_M	1.036	0.47
614_N	619_R	1.036	0.47
173_V	527_P	1.035	0.47
639_N	645_Q	1.034	0.47
59_D	403_V	1.032	0.47
809_G	812_R	1.031	0.47
339_L	401_H	1.030	0.47
466_Q	474_V	1.030	0.47
92_D	226_I	1.028	0.46
175_K	284_R	1.027	0.46
33_G	60_Y	1.027	0.46
730_R	733_Q	1.026	0.46
926_P	938_Q	1.025	0.46
10_Q	263_I	1.022	0.46
630_T	633_S	1.019	0.46
952_E	956_D	1.016	0.46
229_I	363_L	1.015	0.46
222_L	290_S	1.014	0.46
94_L	400_S	1.013	0.45
704_V	707_T	1.012	0.45
693_E	699_V	1.011	0.45
800_R	805_L	1.011	0.45
86_G	361_N	1.009	0.45
203_A	246_A	1.009	0.45
945_E	961_V	1.009	0.45
34_H	435_N	1.008	0.45
707_T	710_E	1.007	0.45
687_K	693_E	1.006	0.45
393_S	449_S	1.004	0.45
165_G	173_V	1.004	0.45
471_C	508_E	1.004	0.45
208_H	493_E	1.002	0.45
139_I	426_L	1.001	0.45
186_F	249_R	1.000	0.45
185_S	239_L	0.998	0.44
926_P	937_A	0.996	0.44
794_M	798_S	0.995	0.44
311_R	415_D	0.995	0.44
704_V	710_E	0.993	0.44
442_I	474_V	0.990	0.44
152_K	527_P	0.989	0.44
885_S	888_V	0.989	0.44
460_N	466_Q	0.988	0.44
34_H	487_L	0.986	0.44
6_I	37_K	0.986	0.44
921_A	928_V	0.985	0.44
912_T	929_I	0.985	0.44
215_V	261_G	0.984	0.44
915_P	920_A	0.982	0.43
971_P	974_V	0.978	0.43
75_R	135_R	0.977	0.43
267_S	469_V	0.977	0.43
358_A	378_H	0.976	0.43
606_Q	615_N	0.976	0.43
945_E	948_V	0.974	0.43
277_S	284_R	0.973	0.43
150_E	163_G	0.972	0.43
27_L	87_R	0.971	0.43
204_P	302_I	0.971	0.43
663_T	666_A	0.968	0.42
808_S	811_R	0.968	0.42
385_L	397_G	0.965	0.42
92_D	579_K	0.964	0.42
321_N	395_S	0.964	0.42
147_D	353_V	0.963	0.42
859_Q	869_P	0.963	0.42
11_Q	401_H	0.961	0.42
713_V	716_V	0.960	0.42
320_F	364_R	0.959	0.42
892_V	917_V	0.959	0.42
661_E	664_E	0.958	0.42
186_F	290_S	0.958	0.42
79_P	361_N	0.956	0.42
91_K	321_N	0.955	0.42
964_A	967_V	0.953	0.41
320_F	527_P	0.951	0.41
447_I	492_G	0.950	0.41
912_T	945_E	0.950	0.41
950_P	960_V	0.948	0.41
966_V	971_P	0.948	0.41
16_V	356_Q	0.947	0.41
307_A	484_Y	0.946	0.41
215_V	249_R	0.944	0.41
783_E	981_V	0.941	0.41
78_F	151_L	0.941	0.41
74_A	334_L	0.940	0.41
790_D	793_G	0.938	0.41
717_Q	722_Q	0.937	0.40
18_L	37_K	0.937	0.40
290_S	304_I	0.934	0.40
900_V	915_P	0.933	0.40
209_Q	246_A	0.929	0.40
649_Q	655_E	0.927	0.40
445_V	476_N	0.927	0.40
343_I	525_E	0.927	0.40
933_D	948_V	0.925	0.40
363_L	457_S	0.925	0.40
284_R	364_R	0.925	0.40
860_R	870_M	0.925	0.40
215_V	268_H	0.924	0.40
908_E	911_E	0.923	0.40
252_F	313_G	0.922	0.40
136_A	173_V	0.919	0.39
165_G	214_I	0.918	0.39
201_R	528_A	0.917	0.39
939_E	943_Q	0.916	0.39
279_F	330_I	0.915	0.39
591_T	594_P	0.913	0.39
213_V	244_I	0.912	0.39
284_R	399_S	0.912	0.39
420_S	446_P	0.911	0.39
969_A	972_E	0.911	0.39
672_Q	678_E	0.911	0.39
34_H	175_K	0.909	0.39
34_H	261_G	0.908	0.39
157_S	229_I	0.907	0.39
28_D	356_Q	0.906	0.38
874_V	886_A	0.905	0.38
74_A	381_R	0.905	0.38
801_S	806_R	0.904	0.38
217_A	230_L	0.904	0.38
215_V	247_L	0.904	0.38
478_Q	503_P	0.904	0.38
152_K	190_H	0.901	0.38
671_E	675_P	0.900	0.38
46_I	94_L	0.899	0.38
884_V	890_E	0.897	0.38
673_Q	679_R	0.896	0.38
89_N	321_N	0.896	0.38
689_Q	694_A	0.896	0.38
961_V	970_E	0.895	0.38
190_H	300_T	0.894	0.38
11_Q	400_S	0.893	0.38
943_Q	950_P	0.893	0.38
175_K	244_I	0.892	0.38
25_Y	434_E	0.892	0.38
358_A	377_S	0.892	0.38
867_V	945_E	0.891	0.38
523_R	527_P	0.891	0.38
837_L	840_G	0.891	0.38
916_E	925_Q	0.891	0.38
182_W	186_F	0.889	0.37
243_H	247_L	0.889	0.37
571_L	575_F	0.888	0.37
311_R	377_S	0.888	0.37
60_Y	256_I	0.888	0.37
104_I	483_H	0.888	0.37
93_V	152_K	0.887	0.37
304_I	330_I	0.887	0.37
900_V	913_T	0.886	0.37
610_K	614_N	0.886	0.37
11_Q	408_S	0.884	0.37
190_H	215_V	0.883	0.37
955_A	960_V	0.883	0.37
640_R	644_R	0.883	0.37
884_V	903_A	0.882	0.37
60_Y	368_R	0.881	0.37
906_Q	966_V	0.881	0.37
804_H	810_Q	0.878	0.37
5_L	12_E	0.878	0.37
5_L	13_E	0.878	0.37
7_N	12_E	0.878	0.37
7_N	13_E	0.878	0.37
881_E	895_V	0.878	0.37
666_A	673_Q	0.875	0.37
186_F	261_G	0.873	0.36
831_A	834_S	0.871	0.36
44_G	356_Q	0.871	0.36
439_V	443_V	0.871	0.36
33_G	339_L	0.869	0.36
788_N	793_G	0.869	0.36
10_Q	486_V	0.865	0.36
682_R	686_D	0.863	0.36
189_K	215_V	0.863	0.36
152_K	376_I	0.862	0.36
153_E	157_S	0.862	0.36
33_G	401_H	0.862	0.36
413_V	637_E	0.862	0.36
604_R	613_Q	0.861	0.36
218_F	255_K	0.860	0.36
866_H	870_M	0.859	0.36
914_H	917_V	0.859	0.36
666_A	669_A	0.859	0.36
608_R	612_R	0.857	0.35
893_A	940_V	0.854	0.35
233_N	491_K	0.854	0.35
280_Q	419_L	0.854	0.35
723_R	730_R	0.853	0.35
888_V	896_V	0.852	0.35
32_P	401_H	0.852	0.35
940_V	943_Q	0.851	0.35
952_E	968_V	0.851	0.35
166_L	330_I	0.849	0.35
104_I	504_K	0.849	0.35
262_E	489_V	0.849	0.35
884_V	933_D	0.848	0.35
940_V	946_P	0.847	0.35
721_K	725_L	0.847	0.35
39_A	63_E	0.845	0.35
806_R	812_R	0.844	0.35
423_I	487_L	0.844	0.35
893_A	899_P	0.844	0.35
139_I	470_R	0.842	0.35
561_T	872_T	0.842	0.35
70_L	168_V	0.842	0.35
768_V	771_P	0.842	0.35
311_R	440_H	0.840	0.34
709_Q	713_V	0.838	0.34
928_V	931_E	0.837	0.34
320_F	410_T	0.837	0.34
942_E	961_V	0.835	0.34
27_L	426_L	0.833	0.34
410_T	413_V	0.833	0.34
85_H	368_R	0.832	0.34
931_E	934_V	0.832	0.34
671_E	677_R	0.832	0.34
438_E	443_V	0.831	0.34
81_N	438_E	0.831	0.34
933_D	959_E	0.830	0.34
31_S	224_Q	0.830	0.34
125_S	215_V	0.829	0.34
646_A	652_E	0.829	0.34
965_E	972_E	0.828	0.34
437_Q	489_V	0.827	0.34
965_E	969_A	0.827	0.34
861_E	866_H	0.827	0.34
968_V	974_V	0.827	0.34
946_P	950_P	0.826	0.34
18_L	304_I	0.825	0.34
101_I	441_A	0.824	0.33
876_V	967_V	0.824	0.33
870_M	954_T	0.824	0.33
521_R	526_Q	0.821	0.33
911_E	945_E	0.821	0.33
32_P	229_I	0.821	0.33
400_S	415_D	0.821	0.33
415_D	470_R	0.820	0.33
33_G	493_E	0.820	0.33
798_S	805_L	0.819	0.33
343_I	477_D	0.817	0.33
179_A	187_R	0.817	0.33
904_E	907_P	0.817	0.33
246_A	255_K	0.817	0.33
962_E	978_A	0.816	0.33
831_A	835_P	0.815	0.33
82_Y	125_S	0.815	0.33
651_A	660_A	0.814	0.33
416_N	432_L	0.814	0.33
267_S	410_T	0.812	0.33
27_L	330_I	0.810	0.33
32_P	339_L	0.810	0.33
936_V	944_A	0.810	0.33
950_P	962_E	0.808	0.33
667_R	673_Q	0.808	0.33
927_Q	931_E	0.807	0.32
89_N	92_D	0.806	0.32
437_Q	461_A	0.806	0.32
449_S	474_V	0.806	0.32
37_K	351_T	0.806	0.32
400_S	432_L	0.806	0.32
56_A	214_I	0.805	0.32
37_K	422_S	0.804	0.32
31_S	205_F	0.803	0.32
792_G	809_G	0.803	0.32
914_H	928_V	0.803	0.32
800_R	806_R	0.803	0.32
497_T	501_M	0.802	0.32
201_R	399_S	0.802	0.32
356_Q	431_A	0.800	0.32
239_L	246_A	0.800	0.32
918_I	937_A	0.800	0.32
434_E	496_P	0.799	0.32
209_Q	385_L	0.798	0.32
34_H	190_H	0.798	0.32
190_H	268_H	0.798	0.32
410_T	512_L	0.798	0.32
807_V	817_D	0.798	0.32
86_G	93_V	0.797	0.32
662_V	665_K	0.797	0.32
84_A	492_G	0.797	0.32
261_G	450_Y	0.796	0.32
902_V	930_T	0.796	0.32
165_G	273_S	0.795	0.32
229_I	440_H	0.793	0.32
31_S	412_T	0.793	0.32
273_S	378_H	0.793	0.32
25_Y	223_R	0.792	0.32
805_L	812_R	0.791	0.32
867_V	873_E	0.790	0.31
11_Q	60_Y	0.790	0.31
930_T	940_V	0.789	0.31
883_V	976_Q	0.789	0.31
32_P	417_E	0.789	0.31
364_R	466_Q	0.789	0.31
237_L	247_L	0.788	0.31
243_H	529_L	0.787	0.31
493_E	504_K	0.785	0.31
607_D	612_R	0.784	0.31
374_I	440_H	0.784	0.31
840_G	846_Y	0.783	0.31
522_K	527_P	0.783	0.31
711_E	724_Q	0.783	0.31
629_R	773_V	0.782	0.31
440_H	474_V	0.782	0.31
62_A	399_S	0.780	0.31
677_R	683_R	0.779	0.31
959_E	964_A	0.779	0.31
252_F	256_I	0.777	0.31
239_L	492_G	0.777	0.31
80_A	229_I	0.777	0.31
712_R	716_V	0.777	0.31
224_Q	438_E	0.776	0.31
277_S	401_H	0.776	0.31
805_L	810_Q	0.776	0.31
261_G	374_I	0.775	0.31
252_F	422_S	0.775	0.31
63_E	678_E	0.775	0.31
962_E	977_P	0.775	0.31
6_I	223_R	0.775	0.31
413_V	854_V	0.774	0.31
357_R	364_R	0.774	0.31
284_R	300_T	0.773	0.30
927_Q	934_V	0.773	0.30
894_G	917_V	0.772	0.30
98_Q	207_I	0.772	0.30
153_E	343_I	0.772	0.30
160_L	529_L	0.771	0.30
175_K	525_E	0.771	0.30
59_D	469_V	0.770	0.30
804_H	812_R	0.770	0.30
6_I	376_I	0.770	0.30
32_P	438_E	0.769	0.30
925_Q	928_V	0.768	0.30
393_S	498_L	0.767	0.30
691_Q	697_L	0.766	0.30
944_A	955_A	0.765	0.30
690_A	697_L	0.764	0.30
680_S	685_D	0.763	0.30
243_H	367_V	0.762	0.30
311_R	410_T	0.761	0.30
956_D	960_V	0.760	0.30
27_L	86_G	0.760	0.30
218_F	247_L	0.759	0.30
195_K	239_L	0.759	0.30
871_V	954_T	0.759	0.30
175_K	483_H	0.758	0.30
301_A	477_D	0.757	0.30
966_V	969_A	0.755	0.29
864_E	909_V	0.755	0.29
932_S	938_Q	0.754	0.29
964_A	977_P	0.754	0.29
37_K	273_S	0.753	0.29
760_A	763_T	0.753	0.29
896_V	899_P	0.751	0.29
339_L	435_N	0.750	0.29
362_R	365_E	0.750	0.29
49_I	410_T	0.749	0.29
267_S	504_K	0.746	0.29
926_P	934_V	0.745	0.29
78_F	90_I	0.745	0.29
888_V	904_E	0.745	0.29
886_A	890_E	0.745	0.29
675_P	678_E	0.744	0.29
967_V	974_V	0.744	0.29
911_E	914_H	0.743	0.29
269_Y	369_Q	0.742	0.29
899_P	904_E	0.742	0.29
165_G	212_N	0.741	0.29
942_E	967_V	0.741	0.29
269_Y	279_F	0.740	0.29
946_P	962_E	0.739	0.29
205_F	466_Q	0.739	0.29
882_P	948_V	0.738	0.29
25_Y	399_S	0.738	0.29
208_H	402_H	0.738	0.29
311_R	535_P	0.737	0.28
911_E	924_E	0.737	0.28
31_S	387_M	0.737	0.28
175_K	243_H	0.736	0.28
269_Y	525_E	0.736	0.28
883_V	906_Q	0.735	0.28
378_H	419_L	0.735	0.28
427_I	458_A	0.735	0.28
624_D	628_E	0.735	0.28
955_A	972_E	0.734	0.28
706_E	712_R	0.734	0.28
369_Q	399_S	0.733	0.28
609_R	617_R	0.733	0.28
175_K	215_V	0.732	0.28
143_I	176_S	0.731	0.28
5_L	8_A	0.731	0.28
8_A	12_E	0.731	0.28
8_A	13_E	0.731	0.28
239_L	416_N	0.731	0.28
764_E	768_V	0.730	0.28
27_L	31_S	0.730	0.28
70_L	100_V	0.730	0.28
435_N	491_K	0.730	0.28
165_G	300_T	0.730	0.28
401_H	416_N	0.729	0.28
11_Q	403_V	0.729	0.28
726_N	730_R	0.728	0.28
267_S	415_D	0.727	0.28
721_K	730_R	0.727	0.28
736_A	788_N	0.727	0.28
208_H	268_H	0.727	0.28
249_R	300_T	0.726	0.28
759_P	762_R	0.726	0.28
229_I	491_K	0.725	0.28
949_E	952_E	0.725	0.28
656_S	662_V	0.724	0.28
4_M	151_L	0.723	0.28
720_R	730_R	0.723	0.28
890_E	896_V	0.721	0.28
446_P	462_I	0.721	0.28
27_L	441_A	0.720	0.28
961_V	969_A	0.720	0.28
136_A	273_S	0.719	0.28
223_R	422_S	0.719	0.28
895_V	902_V	0.719	0.28
624_D	627_S	0.718	0.27
160_L	523_R	0.718	0.27
185_S	255_K	0.717	0.27
157_S	267_S	0.715	0.27
895_V	911_E	0.715	0.27
960_V	963_T	0.715	0.27
869_P	902_V	0.714	0.27
241_R	253_S	0.714	0.27
828_L	836_E	0.713	0.27
955_A	959_E	0.713	0.27
242_Q	245_A	0.713	0.27
263_I	378_H	0.713	0.27
844_I	848_I	0.712	0.27
399_S	527_P	0.712	0.27
18_L	222_L	0.711	0.27
27_L	149_T	0.711	0.27
363_L	435_N	0.711	0.27
154_A	527_P	0.710	0.27
374_I	532_F	0.710	0.27
558_A	867_V	0.708	0.27
234_P	258_L	0.707	0.27
136_A	378_H	0.706	0.27
471_C	484_Y	0.706	0.27
671_E	674_A	0.705	0.27
86_G	212_N	0.705	0.27
378_H	486_V	0.704	0.27
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721_K	727_Q	0.702	0.27
915_P	965_E	0.701	0.27
589_K	594_P	0.701	0.27
205_F	246_A	0.700	0.27
85_H	397_G	0.700	0.27
732_E	738_E	0.699	0.26
422_S	466_Q	0.699	0.26
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262_E	468_G	0.699	0.26
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376_I	449_S	0.697	0.26
957_I	978_A	0.696	0.26
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60_Y	163_G	0.695	0.26
152_K	438_E	0.695	0.26
737_E	743_P	0.694	0.26
623_R	628_E	0.693	0.26
354_R	361_N	0.693	0.26
155_L	432_L	0.692	0.26
604_R	607_D	0.691	0.26
913_T	921_A	0.691	0.26
208_H	243_H	0.691	0.26
778_P	782_E	0.690	0.26
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965_E	977_P	0.687	0.26
439_V	474_V	0.686	0.26
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163_G	173_V	0.685	0.26
918_I	921_A	0.684	0.26
242_Q	253_S	0.684	0.26
228_E	277_S	0.683	0.26
49_I	73_I	0.683	0.26
724_Q	727_Q	0.682	0.26
311_R	792_G	0.681	0.26
434_E	485_H	0.681	0.26
230_L	269_Y	0.681	0.26
415_D	461_A	0.680	0.25
263_I	439_V	0.680	0.25
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157_S	177_A	0.676	0.25
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273_S	419_L	0.674	0.25
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634_D	641_R	0.673	0.25
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415_D	502_L	0.670	0.25
263_I	438_E	0.670	0.25
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253_S	256_I	0.666	0.25
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529_L	534_M	0.663	0.25
831_A	837_L	0.663	0.25
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300_T	527_P	0.656	0.24
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187_R	218_F	0.523	0.18
929_I	945_E	0.523	0.18
625_T	636_R	0.523	0.18
637_E	647_Q	0.523	0.18
102_V	439_V	0.522	0.18
223_R	426_L	0.522	0.18
62_A	213_V	0.522	0.18
724_Q	729_V	0.521	0.18
79_P	277_S	0.521	0.18
801_S	807_V	0.521	0.18
73_I	143_I	0.521	0.18
84_A	255_K	0.521	0.18
311_R	506_H	0.521	0.18
32_P	435_N	0.521	0.18
32_P	166_L	0.520	0.18
397_G	462_I	0.520	0.18
385_L	510_M	0.520	0.18
176_S	415_D	0.519	0.18
62_A	422_S	0.519	0.18
119_F	135_R	0.519	0.18
708_E	714_R	0.518	0.18
212_N	304_I	0.518	0.18
403_V	419_L	0.518	0.18
566_A	658_Q	0.518	0.18
198_A	203_A	0.518	0.18
233_N	239_L	0.518	0.18
798_S	808_S	0.518	0.18
139_I	282_E	0.517	0.18
209_Q	423_I	0.517	0.18
311_R	320_F	0.516	0.18
864_E	954_T	0.516	0.18
249_R	402_H	0.516	0.18
31_S	423_I	0.515	0.18
79_P	125_S	0.515	0.18
653_T	656_S	0.515	0.18
33_G	218_F	0.514	0.18
37_K	165_G	0.514	0.18
104_I	224_Q	0.514	0.18
877_A	884_V	0.513	0.18
950_P	964_A	0.513	0.18
73_I	387_M	0.513	0.18
868_Q	874_V	0.513	0.18
27_L	422_S	0.512	0.18
925_Q	935_A	0.512	0.18
206_L	230_L	0.512	0.18
666_A	670_D	0.512	0.18
187_R	247_L	0.511	0.18
659_Q	662_V	0.511	0.18
610_K	618_D	0.511	0.18
887_P	892_V	0.511	0.18
492_G	506_H	0.510	0.18
81_N	385_L	0.510	0.18
671_E	684_N	0.509	0.18
896_V	906_Q	0.509	0.18
203_A	490_R	0.508	0.18
918_I	930_T	0.508	0.18
460_N	506_H	0.508	0.18
641_R	647_Q	0.508	0.18
62_A	282_E	0.507	0.18
354_R	805_L	0.507	0.18
94_L	410_T	0.507	0.18
660_A	908_E	0.507	0.18
716_V	719_R	0.506	0.18
82_Y	88_P	0.505	0.18
376_I	460_N	0.505	0.18
878_A	923_T	0.505	0.18
889_V	957_I	0.505	0.18
76_E	255_K	0.505	0.18
523_R	530_A	0.505	0.18
136_A	214_I	0.504	0.18
157_S	189_K	0.504	0.18
901_Q	948_V	0.504	0.18
934_V	942_E	0.504	0.18
978_A	981_V	0.503	0.18
630_T	634_D	0.503	0.18
93_V	256_I	0.502	0.18
689_Q	693_E	0.502	0.18
802_P	809_G	0.502	0.18
37_K	473_I	0.502	0.18
182_W	307_A	0.502	0.18
182_W	364_R	0.501	0.17
401_H	423_I	0.501	0.17
965_E	971_P	0.501	0.17
930_T	937_A	0.501	0.17
872_T	939_E	0.500	0.17
949_E	965_E	0.500	0.17
710_E	714_R	0.500	0.17

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2bx2L	3	0.4637	100	0.588	Contact Map
4oxpA	1	0.1678	100	0.843	Contact Map
3cw2C	1	0.2177	100	0.92	Contact Map
1kl9A	2	0.1423	99.8	0.951	Contact Map
3aevA	1	0.1376	98.8	0.974	Contact Map
4nngA	1	0.147	98.7	0.975	Contact Map
2cqoA	1	0.1008	98.3	0.978	Contact Map
4aidA	3	0.0047	98.1	0.979	Contact Map
2khjA	1	0.0829	98	0.979	Contact Map
4toiA	2	0.0735	98	0.98	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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