GREMLIN Database
RNE - Ribonuclease E
UniProt: P21513 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10859
Length: 1061 (962)
Sequences: 747 (658)
Seq/√Len: 21.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
526_Q530_A9.2201.00
720_R723_R5.4071.00
49_I94_L5.0421.00
527_P530_A4.8931.00
639_N642_N4.7951.00
694_A697_L4.4241.00
648_Q651_A4.3681.00
719_R722_Q4.0141.00
328_D362_R3.9001.00
527_P532_F3.8801.00
78_F119_F3.7291.00
524_P527_P3.5951.00
680_S684_N3.5161.00
525_E530_A3.4651.00
571_L574_F3.4311.00
688_R691_Q3.4121.00
328_D366_A3.3991.00
420_S447_I3.3571.00
527_P531_T3.3241.00
672_Q675_P3.2191.00
645_Q648_Q3.1801.00
651_A654_R3.1331.00
279_F385_L3.1111.00
104_I377_S3.0320.99
682_R688_R3.0120.99
801_S804_H2.9700.99
569_G573_R2.9670.99
136_A165_G2.8910.99
705_Q708_E2.8590.99
642_N645_Q2.7930.99
691_Q694_A2.7830.99
711_E714_R2.7480.99
615_N618_D2.7440.99
670_D673_Q2.7120.99
526_Q531_T2.6880.99
442_I479_M2.6520.99
660_A663_T2.6330.98
478_Q506_H2.6200.98
741_V744_V2.5940.98
401_H410_T2.5790.98
797_R800_R2.5570.98
73_I94_L2.5440.98
442_I476_N2.5420.98
616_R619_R2.5270.98
676_R679_R2.5090.98
529_L532_F2.5060.98
186_F246_A2.5010.98
700_E703_S2.4770.98
725_L728_K2.4610.98
729_V732_E2.4550.98
719_R725_L2.4160.97
657_R660_A2.4150.97
738_E741_V2.3480.97
803_R806_R2.3030.96
570_L573_R2.2860.96
619_R622_R2.2670.96
524_P531_T2.2460.96
439_V493_E2.2320.96
646_A649_Q2.2290.96
708_E711_E2.2020.95
799_R806_R2.1960.95
524_P530_A2.1950.95
641_R644_R2.1920.95
719_R729_V2.1890.95
586_E589_K2.1740.95
261_G268_H2.1640.95
674_A677_R2.1570.95
397_G412_T2.1520.95
267_S401_H2.1500.95
574_F578_L2.1410.94
525_E529_L2.1220.94
627_S630_T2.0860.94
215_V243_H2.0830.94
70_L290_S2.0790.93
173_V300_T2.0780.93
104_I175_K2.0530.93
794_M804_H2.0490.93
426_L484_Y2.0480.93
682_R685_D2.0460.93
669_A672_Q2.0450.93
243_H249_R2.0450.93
697_L700_E2.0400.93
125_S249_R2.0350.93
804_H807_V2.0290.93
720_R726_N2.0280.93
675_P683_R2.0230.93
722_Q730_R2.0220.93
669_A675_P2.0080.92
34_H107_E2.0030.92
190_H243_H2.0000.92
802_P807_V1.9980.92
525_E531_T1.9970.92
32_P173_V1.9940.92
633_S636_R1.9920.92
726_N729_V1.9850.92
727_Q730_R1.9700.91
612_R615_N1.9680.91
295_S301_A1.9670.91
27_L279_F1.9640.91
697_L703_S1.9580.91
79_P95_R1.9530.91
635_N638_E1.9490.91
798_S804_H1.9360.91
606_Q611_P1.9200.90
631_E634_D1.9060.90
714_R717_Q1.9030.90
573_R582_F1.8980.90
922_V933_D1.8890.90
725_L729_V1.8870.90
667_R670_D1.8870.90
614_N618_D1.8800.89
911_E917_V1.8780.89
941_A944_A1.8780.89
503_P506_H1.8760.89
799_R804_H1.8640.89
722_Q725_L1.8580.89
186_F247_L1.8520.89
610_K613_Q1.8490.89
320_F355_H1.8390.88
639_N643_R1.8380.88
526_Q529_L1.8310.88
640_R643_R1.8280.88
19_V22_Q1.8210.88
717_Q720_R1.8180.88
602_P605_Q1.8120.88
801_S808_S1.8120.88
679_R682_R1.8080.87
626_R629_R1.7960.87
914_H931_E1.7870.87
601_K604_R1.7780.87
797_R801_S1.7750.86
921_A924_E1.7700.86
802_P805_L1.7640.86
415_D432_L1.7530.86
722_Q727_Q1.7490.86
443_V449_S1.7470.86
946_P955_A1.7430.85
186_F243_H1.7410.85
732_E735_V1.7400.85
625_T628_E1.7390.85
506_H511_A1.7380.85
186_F190_H1.7210.85
522_K526_Q1.7180.85
125_S175_K1.7110.84
186_F215_V1.7080.84
34_H125_S1.6960.84
401_H415_D1.6930.84
224_Q387_M1.6920.84
579_K582_F1.6900.84
607_D610_K1.6900.84
974_V980_P1.6870.83
672_Q676_R1.6830.83
962_E965_E1.6780.83
32_P355_H1.6710.83
125_S243_H1.6690.83
685_D688_R1.6690.83
911_E916_E1.6560.82
794_M797_R1.6550.82
655_E659_Q1.6500.82
621_E624_D1.6470.82
609_R612_R1.6320.81
719_R730_R1.6310.81
654_R657_R1.6270.81
668_T672_Q1.6270.81
811_R814_R1.6200.81
723_R726_N1.6180.81
166_L279_F1.5990.80
939_E979_A1.5900.80
735_V738_E1.5890.80
263_I474_V1.5880.79
18_L139_I1.5870.79
45_K426_L1.5870.79
600_A604_R1.5870.79
577_A581_L1.5830.79
797_R803_R1.5780.79
244_I477_D1.5760.79
213_V304_I1.5750.79
273_S428_E1.5730.79
70_L309_A1.5690.79
415_D449_S1.5680.79
186_F189_K1.5650.78
267_S466_Q1.5580.78
578_L582_F1.5560.78
105_D307_A1.5540.78
962_E967_V1.5520.78
593_Q596_P1.5490.78
89_N168_V1.5460.78
358_A361_N1.5430.77
618_D621_E1.5400.77
673_Q676_R1.5380.77
723_R727_Q1.5370.77
706_E709_Q1.5360.77
168_V304_I1.5290.77
155_L195_K1.5270.77
229_I435_N1.5240.77
613_Q616_R1.5210.76
795_P807_V1.5200.76
277_S361_N1.5150.76
311_R511_A1.5010.75
643_R646_A1.4960.75
249_R261_G1.4950.75
14_L94_L1.4880.75
834_S840_G1.4830.75
795_P802_P1.4740.74
449_S466_Q1.4720.74
34_H249_R1.4680.74
32_P300_T1.4600.73
809_G814_R1.4590.73
190_H218_F1.4520.73
49_I224_Q1.4490.73
233_N399_S1.4450.73
385_L520_E1.4420.72
201_R205_F1.4390.72
799_R802_P1.4390.72
633_S642_N1.4370.72
649_Q653_T1.4340.72
241_R245_A1.4330.72
725_L731_Y1.4260.72
60_Y229_I1.4240.71
801_S809_G1.4220.71
929_I932_S1.4210.71
569_G574_F1.4200.71
798_S801_S1.4180.71
6_I378_H1.4150.71
632_G635_N1.4150.71
37_K428_E1.4120.71
637_E640_R1.4090.71
25_Y37_K1.4050.70
215_V367_V1.4020.70
542_T545_E1.3980.70
11_Q34_H1.3880.69
11_Q49_I1.3850.69
10_Q500_Y1.3750.69
320_F501_M1.3750.69
208_H231_I1.3740.69
277_S300_T1.3730.69
190_H249_R1.3700.68
972_E978_A1.3660.68
895_V898_A1.3650.68
608_R618_D1.3650.68
922_V925_Q1.3630.68
614_N620_N1.3630.68
644_R648_Q1.3610.68
33_G435_N1.3600.68
10_Q14_L1.3580.68
718_P722_Q1.3580.68
246_A378_H1.3570.68
254_S385_L1.3560.68
31_S351_T1.3560.68
797_R804_H1.3540.67
401_H440_H1.3480.67
208_H355_H1.3470.67
694_A703_S1.3460.67
442_I577_A1.3450.67
226_I267_S1.3430.67
6_I387_M1.3420.67
343_I443_V1.3390.67
916_E919_A1.3390.67
683_R689_Q1.3380.66
719_R728_K1.3370.66
215_V308_R1.3340.66
76_E442_I1.3330.66
309_A535_P1.3330.66
49_I376_I1.3320.66
16_V28_D1.3310.66
796_R800_R1.3230.66
374_I437_Q1.3230.66
25_Y428_E1.3220.66
242_Q246_A1.3220.66
31_S56_A1.3210.65
925_Q941_A1.3170.65
249_R268_H1.3120.65
795_P800_R1.3110.65
629_R632_G1.3080.65
895_V905_P1.3060.65
843_W847_P1.3010.64
403_V408_S1.2940.64
935_A959_E1.2930.64
711_E717_Q1.2930.64
152_K189_K1.2890.64
669_A674_A1.2870.63
560_A563_A1.2860.63
589_K592_E1.2840.63
416_N493_E1.2800.63
794_M799_R1.2780.63
914_H923_T1.2730.63
687_K691_Q1.2720.62
89_N351_T1.2700.62
87_R486_V1.2690.62
794_M801_S1.2690.62
905_P908_E1.2620.62
783_E897_E1.2610.62
925_Q934_V1.2600.62
368_R484_Y1.2590.62
933_D936_V1.2590.62
175_K300_T1.2590.62
608_R611_P1.2580.62
417_E436_T1.2560.61
805_L808_S1.2550.61
959_E963_T1.2530.61
680_S683_R1.2500.61
897_E971_P1.2480.61
753_P756_Q1.2460.61
18_L213_V1.2450.61
139_I252_F1.2440.61
18_L244_I1.2430.61
182_W308_R1.2310.60
681_R687_K1.2290.60
722_Q731_Y1.2260.60
246_A403_V1.2250.59
267_S486_V1.2240.59
243_H300_T1.2240.59
125_S261_G1.2210.59
643_R649_Q1.2200.59
32_P527_P1.2180.59
573_R578_L1.2170.59
14_L263_I1.2160.59
207_I231_I1.2160.59
640_R645_Q1.2150.59
525_E532_F1.2150.59
437_Q498_L1.2110.59
798_S802_P1.2110.59
125_S268_H1.2110.59
258_L461_A1.2080.58
397_G403_V1.2080.58
973_V979_A1.2060.58
521_R524_P1.2000.58
146_D420_S1.1980.58
125_S300_T1.1980.58
690_A693_E1.1970.58
726_N732_E1.1950.58
186_F308_R1.1950.58
526_Q532_F1.1920.57
127_L228_E1.1900.57
458_A476_N1.1890.57
246_A416_N1.1870.57
681_R684_N1.1820.57
218_F256_I1.1760.56
800_R803_R1.1730.56
182_W247_L1.1720.56
721_K724_Q1.1720.56
243_H268_H1.1700.56
611_P615_N1.1690.56
601_K605_Q1.1680.56
6_I25_Y1.1680.56
186_F461_A1.1600.55
958_E967_V1.1600.55
792_G807_V1.1600.55
684_N690_A1.1590.55
573_R581_L1.1580.55
725_L730_R1.1560.55
484_Y579_K1.1560.55
925_Q929_I1.1540.55
155_L385_L1.1540.55
880_I951_Q1.1540.55
34_H243_H1.1520.55
574_F577_A1.1520.55
222_L304_I1.1510.55
438_E470_R1.1460.54
119_F803_R1.1460.54
962_E972_E1.1460.54
175_K249_R1.1450.54
234_P238_E1.1430.54
34_H300_T1.1430.54
79_P82_Y1.1430.54
810_Q813_R1.1430.54
617_R620_N1.1400.54
125_S190_H1.1400.54
870_M879_A1.1370.54
139_I244_I1.1370.54
186_F208_H1.1360.54
163_G251_D1.1340.53
301_A309_A1.1320.53
440_H491_K1.1320.53
224_Q255_K1.1260.53
229_I368_R1.1250.53
679_R683_R1.1240.53
378_H428_E1.1190.53
229_I339_L1.1190.53
932_S935_A1.1180.52
649_Q652_E1.1170.52
240_A328_D1.1170.52
923_T927_Q1.1160.52
724_Q730_R1.1150.52
961_V965_E1.1140.52
31_S352_P1.1120.52
705_Q711_E1.1120.52
603_E606_Q1.1120.52
572_S576_G1.1120.52
798_S809_G1.1100.52
622_R625_T1.1090.52
440_H489_V1.1090.52
105_D423_I1.1080.52
165_G378_H1.1050.52
39_A91_K1.1040.52
352_P364_R1.1000.51
62_A313_G1.0960.51
367_V376_I1.0940.51
675_P685_D1.0910.51
214_I419_L1.0910.51
871_V874_V1.0910.51
804_H809_G1.0880.50
951_Q963_T1.0860.50
320_F330_I1.0830.50
623_R627_S1.0830.50
416_N501_M1.0820.50
70_L222_L1.0780.50
6_I152_K1.0770.50
917_V926_P1.0760.50
91_K395_S1.0750.50
928_V944_A1.0730.49
628_E631_E1.0720.49
343_I438_E1.0710.49
33_G251_D1.0690.49
399_S465_R1.0670.49
277_S435_N1.0660.49
653_T659_Q1.0640.49
875_P924_E1.0600.49
49_I400_S1.0590.48
34_H79_P1.0570.48
570_L574_F1.0560.48
643_R648_Q1.0530.48
235_K354_R1.0530.48
604_R608_R1.0530.48
295_S432_L1.0520.48
965_E968_V1.0520.48
802_P806_R1.0500.48
816_R819_R1.0500.48
369_Q439_V1.0480.48
416_N497_T1.0480.48
432_L440_H1.0480.48
89_N304_I1.0450.48
168_V222_L1.0450.48
34_H268_H1.0450.48
636_R642_N1.0420.47
32_P399_S1.0420.47
611_P630_T1.0410.47
190_H208_H1.0410.47
196_K374_I1.0400.47
243_H261_G1.0400.47
125_S367_V1.0400.47
194_I530_A1.0390.47
136_A212_N1.0380.47
913_T919_A1.0370.47
378_H534_M1.0360.47
614_N619_R1.0360.47
173_V527_P1.0350.47
639_N645_Q1.0340.47
59_D403_V1.0320.47
809_G812_R1.0310.47
339_L401_H1.0300.47
466_Q474_V1.0300.47
92_D226_I1.0280.46
175_K284_R1.0270.46
33_G60_Y1.0270.46
730_R733_Q1.0260.46
926_P938_Q1.0250.46
10_Q263_I1.0220.46
630_T633_S1.0190.46
952_E956_D1.0160.46
229_I363_L1.0150.46
222_L290_S1.0140.46
94_L400_S1.0130.45
704_V707_T1.0120.45
693_E699_V1.0110.45
800_R805_L1.0110.45
86_G361_N1.0090.45
203_A246_A1.0090.45
945_E961_V1.0090.45
34_H435_N1.0080.45
707_T710_E1.0070.45
687_K693_E1.0060.45
393_S449_S1.0040.45
165_G173_V1.0040.45
471_C508_E1.0040.45
208_H493_E1.0020.45
139_I426_L1.0010.45
186_F249_R1.0000.45
185_S239_L0.9980.44
926_P937_A0.9960.44
794_M798_S0.9950.44
311_R415_D0.9950.44
704_V710_E0.9930.44
442_I474_V0.9900.44
152_K527_P0.9890.44
885_S888_V0.9890.44
460_N466_Q0.9880.44
34_H487_L0.9860.44
6_I37_K0.9860.44
921_A928_V0.9850.44
912_T929_I0.9850.44
215_V261_G0.9840.44
915_P920_A0.9820.43
971_P974_V0.9780.43
75_R135_R0.9770.43
267_S469_V0.9770.43
358_A378_H0.9760.43
606_Q615_N0.9760.43
945_E948_V0.9740.43
277_S284_R0.9730.43
150_E163_G0.9720.43
27_L87_R0.9710.43
204_P302_I0.9710.43
663_T666_A0.9680.42
808_S811_R0.9680.42
385_L397_G0.9650.42
92_D579_K0.9640.42
321_N395_S0.9640.42
147_D353_V0.9630.42
859_Q869_P0.9630.42
11_Q401_H0.9610.42
713_V716_V0.9600.42
320_F364_R0.9590.42
892_V917_V0.9590.42
661_E664_E0.9580.42
186_F290_S0.9580.42
79_P361_N0.9560.42
91_K321_N0.9550.42
964_A967_V0.9530.41
320_F527_P0.9510.41
447_I492_G0.9500.41
912_T945_E0.9500.41
950_P960_V0.9480.41
966_V971_P0.9480.41
16_V356_Q0.9470.41
307_A484_Y0.9460.41
215_V249_R0.9440.41
783_E981_V0.9410.41
78_F151_L0.9410.41
74_A334_L0.9400.41
790_D793_G0.9380.41
717_Q722_Q0.9370.40
18_L37_K0.9370.40
290_S304_I0.9340.40
900_V915_P0.9330.40
209_Q246_A0.9290.40
649_Q655_E0.9270.40
445_V476_N0.9270.40
343_I525_E0.9270.40
933_D948_V0.9250.40
363_L457_S0.9250.40
284_R364_R0.9250.40
860_R870_M0.9250.40
215_V268_H0.9240.40
908_E911_E0.9230.40
252_F313_G0.9220.40
136_A173_V0.9190.39
165_G214_I0.9180.39
201_R528_A0.9170.39
939_E943_Q0.9160.39
279_F330_I0.9150.39
591_T594_P0.9130.39
213_V244_I0.9120.39
284_R399_S0.9120.39
420_S446_P0.9110.39
969_A972_E0.9110.39
672_Q678_E0.9110.39
34_H175_K0.9090.39
34_H261_G0.9080.39
157_S229_I0.9070.39
28_D356_Q0.9060.38
874_V886_A0.9050.38
74_A381_R0.9050.38
801_S806_R0.9040.38
217_A230_L0.9040.38
215_V247_L0.9040.38
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82_Y268_H0.5970.22
636_R639_N0.5970.22
6_I73_I0.5960.21
895_V977_P0.5950.21
269_Y412_T0.5950.21
795_P798_S0.5950.21
25_Y273_S0.5940.21
917_V923_T0.5940.21
677_R684_N0.5940.21
801_S814_R0.5940.21
810_Q814_R0.5940.21
880_I899_P0.5930.21
222_L280_Q0.5930.21
883_V887_P0.5930.21
422_S428_E0.5930.21
561_T883_V0.5930.21
652_E655_E0.5930.21
91_K135_R0.5930.21
223_R419_L0.5930.21
793_G807_V0.5920.21
320_F352_P0.5920.21
182_W215_V0.5920.21
888_V957_I0.5920.21
633_S637_E0.5920.21
345_I387_M0.5910.21
601_K946_P0.5900.21
913_T928_V0.5900.21
957_I962_E0.5900.21
437_Q459_V0.5900.21
152_K582_F0.5890.21
125_S529_L0.5890.21
49_I472_V0.5890.21
655_E658_Q0.5890.21
218_F246_A0.5880.21
284_R410_T0.5880.21
465_R528_A0.5880.21
810_Q817_D0.5860.21
212_N410_T0.5860.21
364_R369_Q0.5860.21
457_S464_T0.5850.21
31_S263_I0.5830.21
401_H493_E0.5830.21
647_Q650_T0.5830.21
18_L252_F0.5820.21
898_A922_V0.5820.21
474_V478_Q0.5820.21
917_V922_V0.5810.21
239_L263_I0.5810.21
186_F268_H0.5810.21
267_S503_P0.5810.21
125_S208_H0.5810.21
873_E926_P0.5800.21
321_N410_T0.5800.21
592_E595_A0.5790.21
948_V961_V0.5790.21
282_E290_S0.5790.21
893_A901_Q0.5790.21
741_V756_Q0.5780.21
168_V352_P0.5780.21
563_A875_P0.5770.21
861_E865_V0.5770.21
941_A959_E0.5770.21
802_P814_R0.5760.21
784_N787_D0.5760.21
127_L410_T0.5760.21
100_V227_G0.5760.21
881_E904_E0.5760.21
930_T936_V0.5760.21
86_G224_Q0.5750.21
631_E639_N0.5750.21
878_A920_A0.5750.21
868_Q886_A0.5750.21
597_K600_A0.5750.21
400_S416_N0.5740.20
880_I896_V0.5730.20
898_A912_T0.5730.20
152_K252_F0.5730.20
352_P441_A0.5730.20
14_L189_K0.5720.20
104_I398_E0.5710.20
273_S486_V0.5700.20
173_V311_R0.5690.20
904_E937_A0.5690.20
18_L56_A0.5690.20
902_V981_V0.5690.20
412_T441_A0.5690.20
205_F352_P0.5680.20
247_L461_A0.5680.20
400_S431_A0.5670.20
935_A946_P0.5660.20
435_N440_H0.5660.20
238_E408_S0.5650.20
800_R809_G0.5650.20
127_L277_S0.5650.20
195_K434_E0.5650.20
401_H408_S0.5650.20
125_S186_F0.5640.20
313_G387_M0.5640.20
766_V781_Q0.5640.20
155_L279_F0.5640.20
423_I495_T0.5640.20
399_S458_A0.5640.20
670_D677_R0.5630.20
888_V891_E0.5630.20
301_A377_S0.5630.20
400_S408_S0.5630.20
965_E976_Q0.5630.20
230_L267_S0.5620.20
799_R805_L0.5620.20
914_H929_I0.5620.20
881_E963_T0.5610.20
173_V458_A0.5610.20
733_Q737_E0.5610.20
806_R814_R0.5590.20
79_P152_K0.5590.20
471_C524_P0.5590.20
955_A965_E0.5590.20
181_Q224_Q0.5580.20
718_P724_Q0.5580.20
168_V428_E0.5580.20
592_E596_P0.5570.20
908_E912_T0.5570.20
923_T933_D0.5570.20
864_E869_P0.5560.20
768_V776_T0.5560.20
25_Y32_P0.5560.20
107_E393_S0.5550.20
509_A512_L0.5550.20
737_E909_V0.5550.20
190_H261_G0.5540.20
946_P949_E0.5540.20
646_A651_A0.5540.20
885_S960_V0.5540.20
928_V946_P0.5540.20
884_V887_P0.5540.20
953_E961_V0.5530.20
595_A902_V0.5530.20
197_A368_R0.5520.20
806_R810_Q0.5520.20
111_N308_R0.5520.20
888_V920_A0.5500.19
919_A965_E0.5500.19
436_T439_V0.5480.19
500_Y800_R0.5480.19
233_N304_I0.5460.19
564_A880_I0.5450.19
34_H367_V0.5450.19
163_G339_L0.5450.19
635_N639_N0.5450.19
958_E963_T0.5450.19
60_Y435_N0.5440.19
44_G204_P0.5440.19
45_K239_L0.5440.19
249_R367_V0.5440.19
719_R731_Y0.5430.19
485_H504_K0.5430.19
932_S944_A0.5430.19
80_A403_V0.5430.19
228_E310_T0.5420.19
39_A213_V0.5420.19
924_E978_A0.5420.19
88_P190_H0.5420.19
135_R218_F0.5420.19
176_S486_V0.5420.19
209_Q252_F0.5420.19
39_A155_L0.5400.19
399_S440_H0.5400.19
107_E415_D0.5390.19
32_P224_Q0.5380.19
807_V811_R0.5380.19
18_L330_I0.5380.19
631_E975_A0.5380.19
127_L310_T0.5360.19
205_F241_R0.5360.19
924_E934_V0.5360.19
921_A925_Q0.5350.19
624_D767_K0.5350.19
173_V277_S0.5350.19
623_R921_A0.5350.19
546_P658_Q0.5340.19
420_S470_R0.5340.19
222_L428_E0.5330.19
727_Q731_Y0.5330.19
27_L364_R0.5330.19
236_V401_H0.5320.19
524_P532_F0.5320.19
631_E675_P0.5310.19
886_A941_A0.5300.19
896_V938_Q0.5300.19
23_R477_D0.5300.19
471_C583_S0.5300.19
88_P93_V0.5300.19
364_R423_I0.5300.19
104_I146_D0.5290.19
32_P79_P0.5290.19
592_E597_K0.5290.19
890_E926_P0.5280.19
208_H246_A0.5280.19
397_G422_S0.5280.19
214_I458_A0.5280.19
612_R619_R0.5280.19
634_D640_R0.5270.19
881_E885_S0.5270.19
903_A913_T0.5260.18
18_L212_N0.5260.18
37_K56_A0.5260.18
828_L906_Q0.5260.18
95_R708_E0.5260.18
224_Q241_R0.5260.18
82_Y243_H0.5250.18
23_R368_R0.5240.18
88_P213_V0.5240.18
45_K229_I0.5240.18
159_E193_A0.5240.18
25_Y442_I0.5240.18
91_K577_A0.5230.18
187_R218_F0.5230.18
929_I945_E0.5230.18
625_T636_R0.5230.18
637_E647_Q0.5230.18
102_V439_V0.5220.18
223_R426_L0.5220.18
62_A213_V0.5220.18
724_Q729_V0.5210.18
79_P277_S0.5210.18
801_S807_V0.5210.18
73_I143_I0.5210.18
84_A255_K0.5210.18
311_R506_H0.5210.18
32_P435_N0.5210.18
32_P166_L0.5200.18
397_G462_I0.5200.18
385_L510_M0.5200.18
176_S415_D0.5190.18
62_A422_S0.5190.18
119_F135_R0.5190.18
708_E714_R0.5180.18
212_N304_I0.5180.18
403_V419_L0.5180.18
566_A658_Q0.5180.18
198_A203_A0.5180.18
233_N239_L0.5180.18
798_S808_S0.5180.18
139_I282_E0.5170.18
209_Q423_I0.5170.18
311_R320_F0.5160.18
864_E954_T0.5160.18
249_R402_H0.5160.18
31_S423_I0.5150.18
79_P125_S0.5150.18
653_T656_S0.5150.18
33_G218_F0.5140.18
37_K165_G0.5140.18
104_I224_Q0.5140.18
877_A884_V0.5130.18
950_P964_A0.5130.18
73_I387_M0.5130.18
868_Q874_V0.5130.18
27_L422_S0.5120.18
925_Q935_A0.5120.18
206_L230_L0.5120.18
666_A670_D0.5120.18
187_R247_L0.5110.18
659_Q662_V0.5110.18
610_K618_D0.5110.18
887_P892_V0.5110.18
492_G506_H0.5100.18
81_N385_L0.5100.18
671_E684_N0.5090.18
896_V906_Q0.5090.18
203_A490_R0.5080.18
918_I930_T0.5080.18
460_N506_H0.5080.18
641_R647_Q0.5080.18
62_A282_E0.5070.18
354_R805_L0.5070.18
94_L410_T0.5070.18
660_A908_E0.5070.18
716_V719_R0.5060.18
82_Y88_P0.5050.18
376_I460_N0.5050.18
878_A923_T0.5050.18
889_V957_I0.5050.18
76_E255_K0.5050.18
523_R530_A0.5050.18
136_A214_I0.5040.18
157_S189_K0.5040.18
901_Q948_V0.5040.18
934_V942_E0.5040.18
978_A981_V0.5030.18
630_T634_D0.5030.18
93_V256_I0.5020.18
689_Q693_E0.5020.18
802_P809_G0.5020.18
37_K473_I0.5020.18
182_W307_A0.5020.18
182_W364_R0.5010.17
401_H423_I0.5010.17
965_E971_P0.5010.17
930_T937_A0.5010.17
872_T939_E0.5000.17
949_E965_E0.5000.17
710_E714_R0.5000.17
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2bx2L 3 0.4637 100 0.588 Contact Map
4oxpA 1 0.1678 100 0.843 Contact Map
3cw2C 1 0.2177 100 0.92 Contact Map
1kl9A 2 0.1423 99.8 0.951 Contact Map
3aevA 1 0.1376 98.8 0.974 Contact Map
4nngA 1 0.147 98.7 0.975 Contact Map
2cqoA 1 0.1008 98.3 0.978 Contact Map
4aidA 3 0.0047 98.1 0.979 Contact Map
2khjA 1 0.0829 98 0.979 Contact Map
4toiA 2 0.0735 98 0.98 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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