GREMLIN Database
DPO2 - DNA polymerase II
UniProt: P21189 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10747
Length: 783 (734)
Sequences: 2005 (1229)
Seq/√Len: 45.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
408_R540_D6.0321.00
647_Q681_R5.7011.00
672_K677_E5.2581.00
303_E341_Q5.2411.00
83_C92_Y4.6191.00
558_S561_E4.5251.00
668_E672_K3.9861.00
313_R316_E3.9231.00
463_K471_T3.6981.00
648_F669_T3.6951.00
42_V117_E3.6891.00
673_L682_L3.5081.00
196_E207_K3.4551.00
133_G138_A3.4411.00
155_I208_L3.3711.00
174_G233_L3.3581.00
561_E564_K3.3381.00
200_S203_Q3.2751.00
212_F220_I3.0891.00
651_E655_R2.9481.00
198_V207_K2.8201.00
207_K210_A2.8001.00
532_A536_A2.7981.00
314_M318_D2.7571.00
303_E334_K2.6631.00
201_R236_H2.6041.00
133_G136_V2.6021.00
177_I208_L2.5941.00
531_K535_E2.5651.00
664_E668_E2.5561.00
229_D335_D2.5481.00
384_A468_E2.5481.00
298_Q304_G2.5351.00
360_G379_P2.5341.00
598_F630_V2.4731.00
174_G178_V2.4611.00
68_L71_K2.4281.00
202_P206_E2.4061.00
224_N229_D2.4011.00
750_E754_T2.3841.00
380_R472_N2.3761.00
380_R383_R2.3721.00
83_C89_L2.3521.00
19_T41_S2.3441.00
81_L92_Y2.3331.00
70_L73_F2.2631.00
56_I59_G2.2551.00
537_Q572_H2.2471.00
708_L739_P2.2401.00
374_G509_R2.2171.00
150_L219_V2.2041.00
572_H575_A2.1721.00
720_L723_Q2.1641.00
564_K568_A2.1321.00
216_D248_R2.1201.00
53_A57_L2.1071.00
216_D272_R2.1011.00
165_L168_I2.0931.00
313_R317_I2.0881.00
650_Q654_L2.0871.00
156_D331_Y2.0520.99
174_G177_I2.0500.99
158_E335_D2.0290.99
471_T475_H2.0040.99
45_I81_L1.9990.99
714_Q719_P1.9940.99
571_Q575_A1.9860.99
103_V106_A1.9810.99
297_A338_L1.9760.99
63_F67_P1.9710.99
222_G225_V1.9590.99
618_A634_L1.9490.99
248_R272_R1.9400.99
53_A56_I1.9310.99
733_T748_D1.9310.99
314_M317_I1.9290.99
36_L114_Y1.9210.99
714_Q718_R1.9080.99
674_M750_E1.9030.99
334_K337_E1.8920.99
621_I628_R1.8880.99
568_A572_H1.8800.99
376_L495_I1.8720.99
654_L658_R1.8690.99
110_P117_E1.8650.99
704_R708_L1.8560.99
417_V550_F1.8550.99
235_K238_E1.8450.99
729_K732_W1.8280.99
175_Q178_V1.8280.99
172_G177_I1.8270.99
714_Q720_L1.8190.99
83_C86_H1.8170.99
93_E98_E1.8070.99
164_E167_C1.7980.99
500_Y516_A1.7970.99
317_I324_D1.7950.99
401_G404_V1.7940.98
158_E229_D1.7940.98
185_N188_A1.7930.98
167_C177_I1.7810.98
68_L73_F1.7770.98
92_Y95_R1.7570.98
152_W219_V1.7450.98
224_N228_F1.7390.98
219_V349_M1.7300.98
177_I184_E1.7260.98
86_H110_P1.7250.98
736_G739_P1.7200.98
452_E456_D1.7170.98
290_S295_T1.7100.98
47_A79_Y1.7040.98
479_E482_R1.6990.98
651_E654_L1.6960.98
172_G178_V1.6910.98
335_D520_T1.6880.98
540_D552_W1.6800.98
53_A58_Q1.6680.98
570_V574_N1.6560.97
313_R318_D1.6550.97
198_V204_L1.6520.97
637_V702_H1.6440.97
464_H467_P1.6430.97
672_K678_L1.6400.97
95_R98_E1.6390.97
723_Q747_L1.6370.97
173_C178_V1.6280.97
529_Q532_A1.6240.97
178_V182_G1.6190.97
119_F383_R1.6170.97
456_D518_S1.6160.97
671_D675_A1.6160.97
154_S339_V1.6140.97
156_D335_D1.6130.97
533_L576_W1.6080.97
432_L437_G1.6040.97
68_L72_D1.6020.97
109_R112_E1.5850.97
178_V187_D1.5850.97
69_A72_D1.5790.97
310_P313_R1.5760.97
728_I732_W1.5670.96
224_N278_I1.5670.96
596_T630_V1.5670.96
635_E763_G1.5590.96
708_L735_N1.5550.96
62_G66_T1.5420.96
82_Y85_A1.5410.96
421_K593_E1.5380.96
347_E350_P1.5360.96
178_V336_C1.5330.96
178_V181_L1.5320.96
735_N739_P1.5300.96
181_L184_E1.5210.96
41_S105_E1.5200.96
229_D305_K1.5140.96
665_Y669_T1.5120.96
46_P104_Y1.5100.96
516_A523_G1.5070.96
305_K335_D1.5010.95
156_D229_D1.4980.95
76_Q82_Y1.4890.95
544_G548_S1.4860.95
72_D76_Q1.4840.95
648_F665_Y1.4680.95
431_F526_I1.4580.95
202_P240_Y1.4570.95
174_G187_D1.4560.95
432_L464_H1.4510.94
78_V82_Y1.4510.94
708_L734_T1.4500.94
707_R710_D1.4470.94
21_V114_Y1.4460.94
92_Y98_E1.4450.94
482_R486_K1.4450.94
466_L503_L1.4450.94
117_E385_G1.4410.94
167_C174_G1.4340.94
545_D615_K1.4330.94
289_S646_Q1.4180.94
131_H134_T1.4170.94
401_G520_T1.4140.94
474_W496_M1.4060.94
535_E540_D1.3970.93
688_L703_V1.3950.93
355_R491_A1.3930.93
482_R485_N1.3790.93
686_K722_Y1.3770.93
60_E64_R1.3750.93
153_V212_F1.3680.93
294_E304_G1.3630.92
93_E96_L1.3620.92
81_L84_R1.3550.92
108_V378_F1.3520.92
75_R81_L1.3510.92
171_E178_V1.3500.92
352_L363_V1.3470.92
169_G172_G1.3440.92
596_T619_G1.3430.92
209_N213_A1.3390.92
158_E224_N1.3380.92
417_V619_G1.3380.92
771_N774_T1.3370.92
719_P723_Q1.3350.92
167_C170_L1.3320.92
64_R67_P1.3310.91
724_N728_I1.3180.91
73_F82_Y1.3120.91
80_G84_R1.3110.91
224_N335_D1.3090.91
84_R88_Q1.3080.91
381_M465_C1.3050.91
172_G176_R1.3040.91
180_M183_P1.3020.91
533_L573_V1.3010.91
306_S330_T1.3000.90
189_S192_D1.2980.90
362_P365_R1.2950.90
51_P59_G1.2950.90
218_D272_R1.2930.90
308_D335_D1.2920.90
82_Y89_L1.2910.90
80_G97_R1.2880.90
534_I549_T1.2860.90
72_D92_Y1.2850.90
337_E341_Q1.2850.90
70_L80_G1.2840.90
420_Y426_S1.2840.90
378_F388_A1.2820.90
158_E305_K1.2800.90
69_A73_F1.2770.90
381_M436_V1.2770.90
431_F590_L1.2720.90
158_E228_F1.2710.89
691_P694_E1.2690.89
228_F335_D1.2630.89
733_T736_G1.2590.89
158_E331_Y1.2540.89
206_E210_A1.2530.89
78_V81_L1.2480.89
528_R532_A1.2420.88
282_K291_F1.2420.88
449_H452_E1.2420.88
51_P55_H1.2410.88
75_R83_C1.2370.88
55_H220_I1.2360.88
43_A89_L1.2290.88
55_H59_G1.2190.87
173_C179_Y1.2180.87
182_G187_D1.2160.87
172_G175_Q1.2120.87
172_G179_Y1.2070.87
83_C90_M1.2020.87
473_I492_L1.2000.87
316_E319_R1.1940.86
553_L565_I1.1890.86
724_N727_T1.1860.86
81_L85_A1.1830.86
53_A59_G1.1790.86
335_D401_G1.1790.86
85_A92_Y1.1780.86
52_R55_H1.1770.85
86_H92_Y1.1760.85
422_S494_I1.1750.85
105_E108_V1.1730.85
81_L86_H1.1690.85
526_I530_T1.1690.85
618_A657_F1.1680.85
723_Q730_Y1.1680.85
758_Q773_A1.1650.85
697_R700_P1.1640.85
151_K215_Y1.1580.85
453_G456_D1.1510.84
502_V508_C1.1490.84
70_L78_V1.1470.84
157_I224_N1.1440.84
616_R635_E1.1420.84
73_F78_V1.1420.84
447_P451_T1.1390.84
168_I177_I1.1330.83
555_G562_A1.1300.83
173_C181_L1.1300.83
761_A765_L1.1280.83
185_N189_S1.1270.83
563_A594_Y1.1230.83
123_P353_L1.1230.83
663_Q771_N1.1200.82
71_K75_R1.1190.82
84_R92_Y1.1180.82
179_Y185_N1.1130.82
640_D686_K1.1130.82
504_G702_H1.1110.82
404_V614_K1.1090.82
648_F652_L1.1080.82
78_V83_C1.1040.82
167_C172_G1.0980.81
81_L95_R1.0950.81
40_E64_R1.0910.81
86_H117_E1.0880.81
79_Y82_Y1.0830.80
42_V80_G1.0820.80
78_V84_R1.0790.80
477_R489_S1.0770.80
331_Y335_D1.0750.80
177_I181_L1.0740.80
481_K485_N1.0740.80
427_I526_I1.0730.80
690_R694_E1.0710.80
89_L93_E1.0670.79
75_R84_R1.0670.79
170_L235_K1.0660.79
480_A492_L1.0650.79
305_K331_Y1.0630.79
572_H576_W1.0630.79
635_E638_R1.0590.79
277_G339_V1.0570.79
454_F518_S1.0550.79
273_L378_F1.0520.78
182_G185_N1.0520.78
574_N586_L1.0500.78
700_P703_V1.0500.78
251_S270_K1.0460.78
301_L338_L1.0440.78
178_V189_S1.0440.78
533_L536_A1.0420.78
93_E106_A1.0420.78
168_I174_G1.0370.77
186_G190_S1.0360.77
79_Y83_C1.0340.77
26_A246_L1.0330.77
642_T756_Q1.0310.77
232_M236_H1.0280.77
623_E628_R1.0270.77
228_F278_I1.0260.77
651_E665_Y1.0260.77
172_G185_N1.0260.77
631_F634_L1.0250.76
45_I103_V1.0240.76
68_L78_V1.0240.76
154_S336_C1.0210.76
173_C182_G1.0210.76
276_D401_G1.0210.76
417_V596_T1.0210.76
527_M549_T1.0170.76
273_L363_V1.0160.76
167_C171_E1.0160.76
178_V184_E1.0160.76
479_E483_Q1.0140.76
60_E65_L1.0120.76
86_H90_M1.0090.75
76_Q85_A1.0090.75
409_P613_S1.0080.75
170_L177_I1.0070.75
437_G464_H1.0070.75
602_L618_A1.0050.75
310_P314_M1.0050.75
637_V640_D1.0030.75
751_H763_G0.9990.75
85_A91_N0.9980.75
70_L76_Q0.9980.75
68_L85_A0.9910.74
305_K338_L0.9900.74
464_H468_E0.9900.74
225_V274_I0.9880.74
173_C177_I0.9870.74
312_D317_I0.9860.74
354_E357_T0.9840.73
415_V542_I0.9840.73
86_H95_R0.9810.73
216_D360_G0.9800.73
242_L560_E0.9770.73
22_S35_T0.9770.73
398_A506_T0.9760.73
488_L496_M0.9750.73
86_H98_E0.9750.73
601_F619_G0.9740.73
82_Y88_Q0.9740.73
84_R89_L0.9720.73
170_L185_N0.9720.73
157_I177_I0.9720.73
526_I590_L0.9710.72
641_W645_A0.9710.72
186_G191_L0.9700.72
536_A564_K0.9680.72
664_E667_R0.9660.72
180_M185_N0.9660.72
50_V195_L0.9650.72
60_E63_F0.9600.72
349_M634_L0.9570.71
293_L335_D0.9550.71
328_L358_V0.9550.71
409_P521_M0.9540.71
96_L101_V0.9540.71
56_I63_F0.9520.71
721_Q737_P0.9470.71
46_P76_Q0.9450.70
131_H138_A0.9450.70
354_E488_L0.9440.70
645_A760_V0.9430.70
156_D228_F0.9420.70
311_W314_M0.9420.70
451_T456_D0.9420.70
530_T549_T0.9420.70
81_L89_L0.9410.70
324_D327_A0.9390.70
498_A520_T0.9380.70
122_S360_G0.9350.70
83_C88_Q0.9330.69
292_S297_A0.9300.69
85_A89_L0.9300.69
183_P186_G0.9290.69
19_T22_S0.9260.69
718_R721_Q0.9260.69
175_Q185_N0.9240.69
718_R723_Q0.9240.69
167_C178_V0.9230.69
209_N237_A0.9230.69
382_H385_G0.9210.68
706_A748_D0.9210.68
374_G502_V0.9200.68
19_T86_H0.9190.68
84_R95_R0.9170.68
550_F619_G0.9160.68
76_Q84_R0.9160.68
34_V128_G0.9150.68
52_R66_T0.9140.68
380_R469_I0.9120.68
92_Y97_R0.9100.67
389_P410_G0.9090.67
213_A246_L0.9070.67
174_G192_D0.9070.67
293_L401_G0.9030.67
476_G479_E0.9020.67
161_R318_D0.9000.67
135_I138_A0.9000.67
269_A348_I0.8990.67
229_D331_Y0.8980.66
162_H171_E0.8980.66
43_A92_Y0.8980.66
75_R95_R0.8970.66
81_L98_E0.8950.66
254_E260_F0.8940.66
51_P57_L0.8930.66
88_Q92_Y0.8930.66
557_H561_E0.8920.66
155_I220_I0.8900.66
83_C96_L0.8870.65
370_V511_F0.8870.65
406_D429_R0.8850.65
277_G343_F0.8850.65
113_R117_E0.8830.65
59_G63_F0.8820.65
280_A349_M0.8810.65
94_K98_E0.8790.65
277_G773_A0.8770.65
130_M133_G0.8770.65
421_K591_E0.8770.65
132_N135_I0.8750.64
570_V573_V0.8750.64
85_A88_Q0.8750.64
81_L88_Q0.8750.64
500_Y523_G0.8740.64
421_K467_P0.8740.64
88_Q91_N0.8740.64
257_E260_F0.8710.64
45_I77_P0.8710.64
685_R719_P0.8710.64
384_A465_C0.8700.64
703_V706_A0.8680.64
332_N336_C0.8680.64
509_R635_E0.8670.64
673_L753_L0.8660.64
635_E649_Q0.8660.64
174_G189_S0.8650.64
416_L551_V0.8650.64
333_L592_L0.8640.63
638_R695_Y0.8620.63
700_P704_R0.8610.63
53_A60_E0.8590.63
82_Y95_R0.8580.63
335_D338_L0.8570.63
573_V592_L0.8560.63
158_E332_N0.8550.63
712_E735_N0.8540.63
493_K501_G0.8530.62
79_Y88_Q0.8530.62
289_S295_T0.8530.62
573_V576_W0.8530.62
309_N317_I0.8520.62
120_I647_Q0.8520.62
42_V113_R0.8520.62
526_I586_L0.8510.62
529_Q533_L0.8490.62
180_M246_L0.8480.62
502_V510_F0.8470.62
55_H63_F0.8460.62
279_E282_K0.8440.62
72_D78_V0.8410.61
78_V98_E0.8400.61
559_E599_C0.8390.61
89_L94_K0.8380.61
220_I303_E0.8350.61
186_G192_D0.8340.61
68_L80_G0.8330.61
751_H755_R0.8320.60
631_F653_Y0.8320.60
69_A78_V0.8300.60
643_P647_Q0.8290.60
105_E117_E0.8260.60
50_V54_Q0.8260.60
28_D146_Y0.8260.60
56_I60_E0.8230.60
172_G181_L0.8220.60
737_P740_L0.8190.59
51_P56_I0.8190.59
131_H135_I0.8190.59
134_T138_A0.8190.59
316_E323_E0.8180.59
753_L758_Q0.8160.59
234_Q238_E0.8150.59
655_R658_R0.8140.59
641_W759_P0.8140.59
430_T589_A0.8140.59
167_C181_L0.8120.59
38_P88_Q0.8120.59
86_H89_L0.8110.58
173_C187_D0.8090.58
730_Y751_H0.8090.58
420_Y473_I0.8090.58
176_R329_A0.8070.58
83_C87_R0.8070.58
380_R384_A0.8060.58
156_D224_N0.8060.58
167_C176_R0.8060.58
603_M632_K0.8060.58
293_L331_Y0.8050.58
229_D520_T0.8050.58
496_M639_T0.8050.58
179_Y182_G0.8040.58
177_I187_D0.8030.58
181_L185_N0.8030.58
93_E97_R0.8010.58
448_E451_T0.7990.57
705_A734_T0.7990.57
21_V573_V0.7980.57
85_A90_M0.7970.57
157_I338_L0.7970.57
169_G180_M0.7950.57
433_I450_S0.7940.57
205_L233_L0.7910.57
748_D760_V0.7910.57
669_T672_K0.7900.56
178_V183_P0.7890.56
634_L649_Q0.7890.56
228_F331_Y0.7890.56
28_D49_Q0.7880.56
156_D520_T0.7860.56
182_G188_A0.7840.56
288_F296_V0.7830.56
130_M242_L0.7820.56
34_V126_V0.7820.56
75_R80_G0.7810.56
271_G422_S0.7810.56
181_L192_D0.7800.56
97_R120_I0.7790.55
354_E485_N0.7790.55
172_G180_M0.7790.55
69_A79_Y0.7780.55
79_Y92_Y0.7780.55
281_L284_A0.7770.55
55_H58_Q0.7770.55
209_N245_R0.7760.55
75_R78_V0.7760.55
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434_D437_G0.7140.49
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435_P503_L0.7000.48
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175_Q180_M0.6960.47
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401_G615_K0.6910.47
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69_A84_R0.6890.47
418_L569_L0.6860.46
237_A682_L0.6860.46
68_L81_L0.6850.46
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355_R369_S0.6800.46
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670_I674_M0.6300.41
426_S543_Y0.6300.41
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548_S551_V0.6260.41
63_F127_E0.6260.41
317_I327_A0.6260.41
79_Y84_R0.6250.41
59_G65_L0.6250.41
119_F382_H0.6250.41
130_M138_A0.6250.41
70_L83_C0.6250.41
544_G551_V0.6250.41
692_L707_R0.6240.40
127_E195_L0.6240.40
276_D293_L0.6230.40
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447_P455_L0.6220.40
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52_R65_L0.6200.40
229_D401_G0.6190.40
409_P412_Y0.6190.40
288_F291_F0.6190.40
168_I178_V0.6180.40
63_F66_T0.6170.40
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619_G635_E0.6130.39
179_Y186_G0.6130.39
728_I733_T0.6130.39
62_G91_N0.6130.39
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213_A388_A0.6080.39
241_R665_Y0.6070.39
438_L512_D0.6060.39
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701_P705_A0.6050.39
675_A680_A0.6040.39
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532_A535_E0.6040.39
42_V110_P0.6040.39
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731_V736_G0.6020.38
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399_S504_G0.5990.38
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332_N765_L0.5730.36
615_K638_R0.5730.36
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512_D630_V0.5730.36
25_L432_L0.5720.36
645_A756_Q0.5720.36
415_V718_R0.5720.36
64_R385_G0.5710.36
186_G189_S0.5700.35
420_Y512_D0.5700.35
331_Y338_L0.5690.35
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373_F502_V0.5680.35
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172_G183_P0.5660.35
701_P759_P0.5660.35
173_C176_R0.5650.35
22_S36_L0.5650.35
106_A390_N0.5650.35
493_K548_S0.5640.35
246_L415_V0.5640.35
398_A720_L0.5640.35
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545_D614_K0.5630.35
180_M187_D0.5630.35
224_N331_Y0.5630.35
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402_G520_T0.5630.35
538_G557_H0.5620.35
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652_L720_L0.5600.35
342_I346_T0.5590.34
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38_P181_L0.5590.34
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733_T739_P0.5580.34
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540_D554_K0.5560.34
134_T137_N0.5560.34
382_H388_A0.5560.34
351_F634_L0.5550.34
411_L767_F0.5550.34
80_G85_A0.5550.34
636_T760_V0.5540.34
372_A435_P0.5530.34
180_M192_D0.5530.34
533_L572_H0.5530.34
241_R302_G0.5520.34
713_N718_R0.5510.34
546_T615_K0.5500.34
505_T600_R0.5500.34
221_I428_I0.5490.34
115_L122_S0.5490.34
224_N297_A0.5490.34
404_V520_T0.5490.34
662_Y666_V0.5480.34
501_G548_S0.5470.33
21_V111_P0.5460.33
596_T621_I0.5460.33
616_R682_L0.5440.33
250_N253_L0.5440.33
54_Q66_T0.5430.33
168_I172_G0.5430.33
723_Q743_Q0.5430.33
52_R56_I0.5430.33
80_G86_H0.5430.33
709_A736_G0.5430.33
182_G191_L0.5420.33
480_A483_Q0.5420.33
704_R707_R0.5420.33
316_E322_A0.5420.33
130_M571_Q0.5410.33
83_C95_R0.5410.33
618_A653_Y0.5410.33
41_S85_A0.5400.33
401_G498_A0.5390.33
147_R353_L0.5390.33
44_F250_N0.5390.33
55_H203_Q0.5390.33
48_D63_F0.5390.33
241_R542_I0.5380.33
642_T645_A0.5360.32
568_A571_Q0.5360.32
57_L532_A0.5360.32
86_H93_E0.5360.32
519_I669_T0.5360.32
421_K509_R0.5360.32
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410_G491_A0.5350.32
272_R618_A0.5340.32
198_V203_Q0.5340.32
603_M630_V0.5340.32
329_A334_K0.5340.32
223_W381_M0.5330.32
62_G67_P0.5330.32
152_W221_I0.5330.32
511_F719_P0.5330.32
616_R638_R0.5330.32
569_L592_L0.5330.32
356_A570_V0.5320.32
233_L676_G0.5310.32
204_L678_L0.5310.32
351_F376_L0.5310.32
646_Q770_D0.5310.32
486_K764_I0.5310.32
120_I342_I0.5310.32
27_T30_G0.5300.32
324_D330_T0.5300.32
527_M598_F0.5290.32
293_L404_V0.5290.32
332_N335_D0.5290.32
368_G511_F0.5290.32
170_L179_Y0.5280.32
90_M94_K0.5280.32
505_T619_G0.5270.32
504_G543_Y0.5270.32
757_L770_D0.5260.32
21_V726_G0.5260.32
217_P635_E0.5260.32
669_T678_L0.5250.32
120_I588_S0.5250.32
44_F204_L0.5240.31
407_S524_H0.5240.31
306_S327_A0.5230.31
371_A402_G0.5230.31
173_C189_S0.5230.31
297_A364_D0.5230.31
69_A94_K0.5210.31
448_E456_D0.5210.31
150_L446_D0.5200.31
422_S474_W0.5200.31
54_Q625_D0.5190.31
200_S533_L0.5190.31
431_F527_M0.5190.31
132_N136_V0.5180.31
223_W277_G0.5180.31
425_P633_G0.5170.31
76_Q89_L0.5170.31
539_Y622_Q0.5170.31
444_Q449_H0.5170.31
278_I292_S0.5170.31
655_R665_Y0.5170.31
498_A593_E0.5160.31
598_F645_A0.5150.31
399_S489_S0.5150.31
272_R640_D0.5150.31
547_D615_K0.5150.31
53_A64_R0.5140.31
509_R638_R0.5140.31
491_A523_G0.5140.31
710_D720_L0.5140.31
735_N738_E0.5140.31
699_V707_R0.5130.31
497_N523_G0.5130.31
602_L767_F0.5130.31
467_P496_M0.5120.30
571_Q754_T0.5120.30
450_S456_D0.5120.30
476_G485_N0.5120.30
69_A83_C0.5110.30
254_E258_H0.5100.30
489_S639_T0.5100.30
49_Q55_H0.5100.30
618_A656_I0.5090.30
157_I166_Y0.5090.30
215_Y345_K0.5090.30
18_G39_Q0.5090.30
156_D276_D0.5080.30
112_E371_A0.5080.30
420_Y541_V0.5070.30
280_A284_A0.5070.30
222_G271_G0.5070.30
276_D399_S0.5060.30
342_I404_V0.5050.30
435_P604_P0.5050.30
155_I348_I0.5050.30
453_G525_Q0.5050.30
431_F512_D0.5040.30
152_W668_E0.5040.30
645_A759_P0.5040.30
655_R661_P0.5040.30
52_R59_G0.5030.30
158_E338_L0.5030.30
177_I192_D0.5030.30
390_N509_R0.5030.30
135_I664_E0.5020.30
176_R180_M0.5010.30
78_V92_Y0.5010.30
205_L416_L0.5000.29
168_I183_P0.5000.29
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3k59A 1 0.9757 100 0.176 Contact Map
3iayA 1 0.954 100 0.184 Contact Map
4qclA 1 0.9502 100 0.213 Contact Map
1qhtA 1 0.8544 100 0.222 Contact Map
2gv9A 1 0.9553 100 0.223 Contact Map
4fvmA 1 0.9119 100 0.239 Contact Map
4m8oA 1 0.9579 100 0.27 Contact Map
1s5jA 1 0.8008 100 0.293 Contact Map
3qexA 1 0.917 100 0.302 Contact Map
2py5A 2 0.5722 100 0.672 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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