FADB - ECOLI - GREMLIN Contacts

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FADB - Fatty acid oxidation complex subunit alpha

UniProt:	P21177	Sequences: MLYKGDTLYLDWLEDGIAELVFDAPGSVNKLDTATVASLGEAIGVLEQQSDLKGLLLRSNKAAFIVGADITEFLSLFLVPEEQLSQWLHFANSVFNRLEDLPVPTIAAVNGYALGGGCECVLATDYRLATPDLRIGLPETKLGIMPGFGGSVRMPRMLGADSALEIIAAGKDVGADQALKIGLVDGVVKAEKLVEGAKAVLRQAINGDLDWKAKRQPKLEPLKLSKIEATMSFTIAKGMVAQTAGKHYPAPITAVKTIEAAARFGREEALNLENKSFVPLAHTNEARALVGIFLNDQYVKGKAKKLTKDVETPKQAAVLGAGIMGGGIAYQSAWKGVPVVMKDINDKSLTLGMTEAAKLLNKQLERGKIDGLKLAGVISTIHPTLDYAGFDRVDIVVEAVVENPKVKKAVLAETEQKVRQDTVLASNTSTIPISELANALERPENFCGMHFFNPVHRMPLVEIIRGEKSSDETIAKVVAWASKMGKTPIVVNDCPGFFVNRVLFPYFAGFSQLLRDGADFRKIDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVMAAGFPQRMQKDYRDAIDALFDANRFGQKNGLGFWRYKEDSKGKPKKEEDAAVEDLLAEVSQPKRDFSEEEIIARMMIPMVNEVVRCLEEGIIATPAEADMALVYGLGFPPFHGGAFRWLDTLGSAKYLDMAQQYQHLGPLYEVPEGLRNKARHNEPYYPPVEPARPVGDLKTA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10279
Length:	729 (686)
Sequences:	2597 (1550)
Seq/√Len:	59.2

ECOLI - FADB FADJ

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
346_D	350_T	5.985	1.00
688_Q	704_R	5.019	1.00
47_E	97_R	4.453	1.00
167_I	254_A	3.562	1.00
371_G	375_A	3.461	1.00
442_R	445_N	3.448	1.00
333_A	381_I	3.420	1.00
396_V	418_V	3.356	1.00
107_A	124_T	3.294	1.00
114_L	136_G	3.280	1.00
364_L	369_I	3.233	1.00
44_G	97_R	3.151	1.00
491_V	498_F	3.110	1.00
265_G	268_E	3.100	1.00
629_A	686_M	2.940	1.00
292_I	659_V	2.900	1.00
129_A	184_V	2.871	1.00
461_V	481_A	2.849	1.00
118_C	135_I	2.841	1.00
444_E	468_K	2.838	1.00
152_V	269_A	2.819	1.00
332_S	480_W	2.765	1.00
315_Q	392_R	2.691	1.00
418_V	422_T	2.670	1.00
705_N	709_H	2.662	1.00
317_A	390_F	2.655	1.00
522_K	624_E	2.650	1.00
95_F	123_A	2.624	1.00
409_A	413_E	2.595	1.00
434_S	467_E	2.593	1.00
612_L	619_K	2.541	1.00
701_E	705_N	2.499	1.00
364_L	374_L	2.489	1.00
23_D	60_N	2.450	1.00
404_P	435_E	2.426	1.00
400_V	410_V	2.415	1.00
253_T	279_P	2.339	1.00
481_A	488_P	2.324	1.00
257_T	276_S	2.314	1.00
164_L	258_I	2.313	1.00
384_T	389_G	2.304	1.00
636_V	674_W	2.283	1.00
361_N	374_L	2.273	1.00
264_F	272_L	2.270	1.00
145_M	254_A	2.253	1.00
426_S	433_I	2.241	1.00
550_H	576_F	2.232	1.00
131_P	189_K	2.230	1.00
154_M	183_L	2.199	1.00
54_G	201_L	2.174	1.00
639_V	672_F	2.172	1.00
65_I	120_C	2.154	1.00
134_R	172_D	2.146	1.00
316_A	395_I	2.143	1.00
623_S	626_E	2.112	1.00
158_L	162_S	2.102	1.00
317_A	393_V	2.102	1.00
435_E	438_N	2.100	1.00
415_E	440_L	2.099	1.00
625_E	629_A	2.098	1.00
16_G	53_K	2.050	1.00
316_A	332_S	2.040	1.00
158_L	181_I	2.032	1.00
186_G	203_Q	2.014	1.00
553_Q	573_D	2.009	1.00
412_A	439_A	2.006	1.00
644_E	702_G	2.005	1.00
286_A	290_V	1.998	1.00
330_Y	359_L	1.996	1.00
357_A	361_N	1.974	1.00
137_L	154_M	1.960	1.00
321_A	352_G	1.925	1.00
46_L	55_L	1.922	1.00
360_L	377_V	1.909	1.00
547_D	584_K	1.908	1.00
188_V	196_G	1.899	1.00
527_M	631_M	1.896	1.00
411_L	424_L	1.853	1.00
15_D	202_R	1.850	1.00
311_E	472_E	1.838	1.00
63_A	112_Y	1.838	1.00
266_R	270_L	1.830	1.00
167_I	258_I	1.830	1.00
684_L	707_A	1.828	1.00
338_P	380_T	1.814	0.99
109_V	135_I	1.804	0.99
408_K	439_A	1.803	0.99
593_K	596_S	1.799	0.99
643_L	654_A	1.767	0.99
686_M	689_Q	1.760	0.99
376_G	380_T	1.756	0.99
55_L	103_V	1.747	0.99
658_L	671_A	1.738	0.99
129_A	135_I	1.734	0.99
470_S	473_T	1.734	0.99
145_M	257_T	1.725	0.99
249_P	285_E	1.711	0.99
421_D	445_N	1.696	0.99
640_V	675_L	1.692	0.99
526_V	628_I	1.683	0.99
47_E	101_L	1.681	0.99
415_E	441_E	1.678	0.99
21_V	58_R	1.677	0.99
162_S	165_E	1.676	0.99
105_T	125_D	1.669	0.99
702_G	706_K	1.663	0.99
109_V	113_A	1.651	0.99
35_T	39_L	1.650	0.99
22_F	65_I	1.637	0.99
681_A	685_D	1.632	0.99
509_G	516_D	1.629	0.99
423_V	473_T	1.624	0.99
684_L	704_R	1.604	0.99
370_D	373_K	1.603	0.99
118_C	183_L	1.597	0.99
534_P	540_L	1.592	0.99
216_Q	220_E	1.589	0.99
351_L	355_E	1.582	0.99
145_M	280_L	1.577	0.99
375_A	379_S	1.575	0.99
395_I	480_W	1.571	0.99
342_K	387_Y	1.567	0.99
416_Q	441_E	1.566	0.99
13_L	198_K	1.557	0.98
374_L	378_I	1.549	0.98
334_W	377_V	1.529	0.98
235_I	238_G	1.518	0.98
158_L	183_L	1.510	0.98
46_L	52_L	1.507	0.98
215_R	219_L	1.507	0.98
406_V	409_A	1.498	0.98
96_N	100_D	1.495	0.98
134_R	174_G	1.488	0.98
633_I	678_L	1.487	0.98
373_K	376_G	1.487	0.98
22_F	35_T	1.483	0.98
408_K	435_E	1.481	0.98
184_V	187_V	1.479	0.98
360_L	374_L	1.475	0.98
449_M	477_V	1.472	0.98
13_L	19_E	1.470	0.98
272_L	275_K	1.468	0.98
349_L	385_L	1.467	0.98
59_S	63_A	1.466	0.98
166_I	173_V	1.466	0.98
654_A	672_F	1.455	0.98
158_L	166_I	1.449	0.98
406_V	410_V	1.445	0.97
512_Q	515_R	1.445	0.97
494_C	647_I	1.444	0.97
259_E	263_R	1.443	0.97
166_I	181_I	1.439	0.97
503_L	540_L	1.433	0.97
40_G	97_R	1.433	0.97
704_R	708_R	1.433	0.97
211_W	214_K	1.433	0.97
154_M	158_L	1.430	0.97
171_K	177_Q	1.426	0.97
651_P	676_D	1.425	0.97
498_F	657_A	1.423	0.97
447_C	477_V	1.420	0.97
685_D	688_Q	1.418	0.97
465_R	471_D	1.411	0.97
85_S	89_H	1.410	0.97
177_Q	181_I	1.408	0.97
155_P	158_L	1.404	0.97
390_F	393_V	1.400	0.97
17_I	56_L	1.392	0.97
434_S	493_D	1.388	0.97
257_T	272_L	1.387	0.97
463_I	478_V	1.386	0.97
216_Q	219_L	1.384	0.97
98_L	105_T	1.382	0.97
466_G	469_S	1.377	0.97
514_L	523_I	1.375	0.97
550_H	577_D	1.370	0.96
648_I	654_A	1.355	0.96
301_G	304_K	1.354	0.96
193_L	197_A	1.353	0.96
371_G	374_L	1.349	0.96
301_G	305_K	1.348	0.96
404_P	436_L	1.347	0.96
131_P	176_D	1.347	0.96
215_R	218_K	1.343	0.96
489_I	657_A	1.341	0.96
108_A	197_A	1.335	0.96
408_K	412_A	1.335	0.96
354_T	358_K	1.332	0.96
95_F	120_C	1.327	0.96
587_L	603_E	1.325	0.96
449_M	481_A	1.319	0.96
684_L	688_Q	1.319	0.96
349_L	352_G	1.313	0.96
82_E	86_Q	1.311	0.95
531_F	674_W	1.309	0.95
140_T	251_P	1.308	0.95
516_D	630_R	1.307	0.95
513_L	518_A	1.306	0.95
21_V	60_N	1.305	0.95
502_V	635_M	1.304	0.95
211_W	216_Q	1.300	0.95
498_F	671_A	1.294	0.95
430_T	552_A	1.294	0.95
166_I	183_L	1.293	0.95
210_D	213_A	1.292	0.95
16_G	202_R	1.291	0.95
550_H	573_D	1.290	0.95
629_A	633_I	1.287	0.95
387_Y	417_K	1.285	0.95
491_V	657_A	1.285	0.95
81_E	279_P	1.284	0.95
382_H	389_G	1.282	0.95
43_I	98_L	1.277	0.95
636_V	675_L	1.276	0.95
313_P	483_K	1.273	0.95
386_D	389_G	1.269	0.95
264_F	268_E	1.267	0.95
518_A	522_K	1.267	0.95
609_E	612_L	1.266	0.95
186_G	196_G	1.265	0.94
40_G	94_V	1.265	0.94
528_E	539_Y	1.263	0.94
272_L	276_S	1.252	0.94
620_R	626_E	1.248	0.94
687_A	697_Y	1.248	0.94
99_E	153_R	1.246	0.94
526_V	624_E	1.244	0.94
212_K	215_R	1.241	0.94
404_P	431_I	1.241	0.94
509_G	696_L	1.241	0.94
550_H	554_A	1.239	0.94
629_A	674_W	1.239	0.94
502_V	639_V	1.239	0.94
675_L	683_Y	1.238	0.94
215_R	220_E	1.237	0.94
576_F	581_F	1.236	0.94
37_A	41_E	1.234	0.94
637_N	700_P	1.233	0.94
141_K	666_P	1.228	0.94
605_D	609_E	1.226	0.94
56_L	198_K	1.219	0.93
174_G	177_Q	1.217	0.93
363_Q	369_I	1.217	0.93
316_A	337_V	1.214	0.93
342_K	413_E	1.212	0.93
285_E	288_A	1.212	0.93
141_K	171_K	1.211	0.93
45_V	49_Q	1.209	0.93
52_L	103_V	1.207	0.93
436_L	446_F	1.206	0.93
459_P	487_T	1.205	0.93
234_T	238_G	1.204	0.93
268_E	271_N	1.204	0.93
233_F	237_K	1.201	0.93
302_K	305_K	1.197	0.93
411_L	440_L	1.195	0.93
361_N	364_L	1.194	0.93
350_T	354_T	1.193	0.93
18_A	55_L	1.193	0.93
123_A	153_R	1.190	0.92
198_K	202_R	1.188	0.92
52_L	55_L	1.182	0.92
56_L	201_L	1.179	0.92
165_E	169_A	1.178	0.92
211_W	215_R	1.178	0.92
212_K	219_L	1.176	0.92
346_D	385_L	1.175	0.92
99_E	125_D	1.173	0.92
474_I	490_V	1.171	0.92
518_A	622_F	1.171	0.92
478_V	490_V	1.166	0.92
541_L	549_A	1.162	0.92
311_E	445_N	1.162	0.92
487_T	660_Y	1.154	0.91
519_D	612_L	1.154	0.91
465_R	649_A	1.152	0.91
218_K	221_P	1.152	0.91
357_A	378_I	1.150	0.91
387_Y	410_V	1.150	0.91
81_E	85_S	1.147	0.91
89_H	93_S	1.147	0.91
361_N	365_E	1.146	0.91
106_I	201_L	1.143	0.91
353_M	383_P	1.142	0.91
215_R	221_P	1.141	0.91
550_H	581_F	1.132	0.90
413_E	416_Q	1.130	0.90
625_E	628_I	1.129	0.90
135_I	183_L	1.129	0.90
253_T	280_L	1.127	0.90
574_A	578_A	1.125	0.90
509_G	630_R	1.124	0.90
58_R	61_K	1.122	0.90
237_K	240_V	1.120	0.90
682_K	685_D	1.120	0.90
581_F	585_N	1.120	0.90
545_G	584_K	1.119	0.90
530_Q	624_E	1.117	0.90
405_K	408_K	1.117	0.90
551_H	555_V	1.116	0.90
363_Q	368_K	1.115	0.90
157_M	185_D	1.114	0.90
284_N	677_T	1.110	0.90
335_K	485_G	1.103	0.89
644_E	705_N	1.103	0.89
460_L	661_G	1.096	0.89
17_I	202_R	1.095	0.89
419_R	422_T	1.095	0.89
20_L	55_L	1.093	0.89
74_L	290_V	1.090	0.89
248_Y	666_P	1.086	0.89
561_P	564_M	1.085	0.88
699_V	704_R	1.081	0.88
560_F	563_R	1.081	0.88
395_I	449_M	1.080	0.88
519_D	522_K	1.080	0.88
607_A	610_D	1.078	0.88
89_H	274_N	1.078	0.88
253_T	256_K	1.077	0.88
401_V	453_N	1.074	0.88
361_N	371_G	1.073	0.88
337_V	480_W	1.071	0.88
73_F	281_A	1.071	0.88
314_K	483_K	1.066	0.88
363_Q	366_R	1.060	0.87
695_P	698_E	1.059	0.87
141_K	172_D	1.056	0.87
40_G	44_G	1.054	0.87
606_A	610_D	1.053	0.87
194_V	198_K	1.045	0.87
345_N	348_S	1.040	0.86
154_M	166_I	1.038	0.86
639_V	671_A	1.035	0.86
603_E	606_A	1.034	0.86
604_E	608_V	1.033	0.86
118_C	121_V	1.032	0.86
144_I	286_A	1.031	0.86
240_V	244_A	1.027	0.86
349_L	383_P	1.027	0.86
682_K	686_M	1.026	0.86
195_E	199_A	1.023	0.85
641_R	644_E	1.023	0.85
357_A	375_A	1.022	0.85
459_P	660_Y	1.021	0.85
494_C	500_N	1.019	0.85
499_V	662_L	1.016	0.85
33_T	37_A	1.016	0.85
188_V	193_L	1.016	0.85
214_K	220_E	1.015	0.85
216_Q	221_P	1.014	0.85
128_L	186_G	1.012	0.85
140_T	254_A	1.011	0.85
192_K	195_E	1.010	0.85
495_P	555_V	1.006	0.84
173_V	181_I	1.005	0.84
684_L	699_V	1.001	0.84
362_K	366_R	0.999	0.84
525_K	624_E	0.997	0.84
145_M	276_S	0.993	0.84
354_T	357_A	0.992	0.84
359_L	456_H	0.992	0.84
637_N	703_L	0.991	0.83
633_I	683_Y	0.991	0.83
639_V	654_A	0.989	0.83
555_V	559_G	0.984	0.83
62_A	110_N	0.983	0.83
41_E	44_G	0.983	0.83
210_D	215_R	0.979	0.83
313_P	476_K	0.977	0.83
400_V	406_V	0.977	0.83
165_E	171_K	0.977	0.83
229_A	232_S	0.976	0.83
151_S	269_A	0.976	0.83
514_L	571_A	0.974	0.82
217_P	221_P	0.974	0.82
53_K	59_S	0.973	0.82
404_P	559_G	0.970	0.82
55_L	59_S	0.967	0.82
510_F	631_M	0.967	0.82
256_K	259_E	0.965	0.82
177_Q	180_K	0.963	0.82
96_N	267_E	0.962	0.82
350_T	385_L	0.961	0.82
447_C	474_I	0.960	0.81
593_K	602_K	0.957	0.81
387_Y	413_E	0.952	0.81
240_V	255_V	0.952	0.81
688_Q	699_V	0.952	0.81
49_Q	103_V	0.943	0.80
404_P	408_K	0.942	0.80
405_K	409_A	0.942	0.80
685_D	689_Q	0.941	0.80
257_T	261_A	0.939	0.80
369_I	377_V	0.939	0.80
705_N	708_R	0.937	0.80
503_L	635_M	0.936	0.80
605_D	608_V	0.933	0.80
313_P	316_A	0.929	0.79
210_D	214_K	0.928	0.79
127_R	157_M	0.928	0.79
233_F	240_V	0.927	0.79
644_E	700_P	0.925	0.79
61_K	110_N	0.925	0.79
338_P	382_H	0.923	0.79
418_V	424_L	0.923	0.79
57_L	120_C	0.923	0.79
33_T	72_E	0.921	0.79
159_G	162_S	0.919	0.79
315_Q	338_P	0.917	0.78
312_T	483_K	0.916	0.78
574_A	577_D	0.915	0.78
554_A	576_F	0.915	0.78
55_L	101_L	0.915	0.78
311_E	476_K	0.914	0.78
321_A	341_M	0.913	0.78
453_N	544_V	0.911	0.78
122_L	158_L	0.910	0.78
131_P	188_V	0.909	0.78
334_W	360_L	0.907	0.78
423_V	476_K	0.906	0.78
47_E	102_P	0.906	0.78
46_L	101_L	0.906	0.78
56_L	60_N	0.902	0.77
144_I	277_F	0.902	0.77
580_R	587_L	0.901	0.77
341_M	352_G	0.898	0.77
644_E	701_E	0.895	0.77
587_L	591_R	0.894	0.77
611_L	614_E	0.894	0.77
260_A	272_L	0.893	0.77
640_V	702_G	0.891	0.76
237_K	241_A	0.890	0.76
291_G	673_R	0.889	0.76
681_A	707_A	0.888	0.76
86_Q	89_H	0.886	0.76
675_L	680_S	0.886	0.76
289_L	666_P	0.885	0.76
315_Q	340_V	0.884	0.76
440_L	446_F	0.884	0.76
499_V	648_I	0.883	0.76
554_A	557_A	0.881	0.76
292_I	656_M	0.878	0.75
43_I	97_R	0.875	0.75
411_L	436_L	0.875	0.75
39_L	94_V	0.872	0.75
672_F	675_L	0.872	0.75
420_Q	441_E	0.872	0.75
463_I	488_P	0.871	0.75
50_S	103_V	0.871	0.75
321_A	343_D	0.870	0.75
212_K	220_E	0.869	0.75
274_N	278_V	0.868	0.74
237_K	256_K	0.867	0.74
445_N	470_S	0.863	0.74
241_A	252_I	0.863	0.74
527_M	537_P	0.862	0.74
44_G	48_Q	0.862	0.74
633_I	686_M	0.861	0.74
236_A	240_V	0.861	0.74
390_F	417_K	0.861	0.74
433_I	464_I	0.860	0.74
525_K	530_Q	0.857	0.74
70_I	142_L	0.857	0.74
425_A	447_C	0.856	0.73
357_A	374_L	0.856	0.73
59_S	112_Y	0.855	0.73
330_Y	456_H	0.855	0.73
684_L	687_A	0.854	0.73
444_E	470_S	0.853	0.73
521_R	605_D	0.851	0.73
126_Y	200_V	0.850	0.73
214_K	219_L	0.848	0.73
24_A	32_D	0.848	0.73
681_A	708_R	0.848	0.73
96_N	270_L	0.847	0.73
445_N	473_T	0.844	0.72
310_V	476_K	0.844	0.72
656_M	660_Y	0.844	0.72
106_I	128_L	0.843	0.72
554_A	558_A	0.843	0.72
680_S	710_N	0.841	0.72
287_R	677_T	0.841	0.72
629_A	690_Y	0.841	0.72
437_A	466_G	0.839	0.72
360_L	456_H	0.839	0.72
560_F	565_Q	0.838	0.72
211_W	220_E	0.838	0.72
210_D	216_Q	0.838	0.72
210_D	219_L	0.835	0.72
54_G	59_S	0.835	0.72
253_T	276_S	0.834	0.71
499_V	657_A	0.834	0.71
449_M	480_W	0.834	0.71
408_K	436_L	0.833	0.71
94_V	97_R	0.830	0.71
129_A	175_A	0.829	0.71
557_A	560_F	0.829	0.71
49_Q	52_L	0.829	0.71
581_F	584_K	0.829	0.71
353_M	357_A	0.828	0.71
108_A	193_L	0.826	0.71
283_T	286_A	0.826	0.71
694_G	697_Y	0.826	0.71
678_L	683_Y	0.824	0.71
56_L	194_V	0.823	0.70
415_E	442_R	0.822	0.70
228_E	231_M	0.821	0.70
54_G	60_N	0.820	0.70
463_I	514_L	0.819	0.70
546_I	576_F	0.819	0.70
35_T	38_S	0.819	0.70
102_P	125_D	0.818	0.70
388_A	391_D	0.818	0.70
472_E	476_K	0.818	0.70
282_H	286_A	0.818	0.70
342_K	384_T	0.817	0.70
178_A	184_V	0.817	0.70
58_R	194_V	0.816	0.70
684_L	703_L	0.816	0.70
271_N	275_K	0.814	0.70
531_F	636_V	0.813	0.70
162_S	181_I	0.812	0.69
233_F	236_A	0.808	0.69
449_M	461_V	0.807	0.69
535_M	543_V	0.802	0.68
317_A	340_V	0.801	0.68
515_R	569_R	0.800	0.68
438_N	468_K	0.799	0.68
41_E	45_V	0.799	0.68
316_A	484_M	0.798	0.68
46_L	103_V	0.797	0.68
214_K	218_K	0.795	0.68
498_F	648_I	0.794	0.68
13_L	16_G	0.792	0.68
500_N	648_I	0.792	0.68
507_F	541_L	0.791	0.67
66_V	114_L	0.790	0.67
465_R	490_V	0.789	0.67
554_A	573_D	0.789	0.67
326_G	359_L	0.789	0.67
203_Q	208_D	0.789	0.67
414_T	418_V	0.788	0.67
36_V	72_E	0.788	0.67
469_S	474_I	0.787	0.67
316_A	397_V	0.786	0.67
209_L	212_K	0.786	0.67
277_F	281_A	0.785	0.67
132_D	175_A	0.782	0.67
704_R	707_A	0.782	0.67
35_T	120_C	0.782	0.67
533_W	635_M	0.780	0.66
608_V	612_L	0.779	0.66
637_N	641_R	0.779	0.66
522_K	622_F	0.778	0.66
447_C	473_T	0.778	0.66
81_E	278_V	0.777	0.66
591_R	603_E	0.777	0.66
56_L	61_K	0.776	0.66
498_F	658_L	0.776	0.66
445_N	472_E	0.775	0.66
333_A	356_A	0.775	0.66
330_Y	356_A	0.774	0.66
229_A	233_F	0.772	0.66
318_V	329_A	0.772	0.66
642_C	654_A	0.770	0.65
32_D	35_T	0.770	0.65
210_D	221_P	0.770	0.65
418_V	436_L	0.770	0.65
238_G	241_A	0.769	0.65
573_D	577_D	0.769	0.65
310_V	482_S	0.769	0.65
364_L	375_A	0.769	0.65
593_K	597_K	0.767	0.65
518_A	620_R	0.767	0.65
698_E	701_E	0.766	0.65
91_A	148_F	0.765	0.65
528_E	536_G	0.764	0.65
702_G	705_N	0.764	0.65
579_N	585_N	0.764	0.65
629_A	682_K	0.760	0.64
356_A	381_I	0.758	0.64
226_K	230_T	0.758	0.64
19_E	56_L	0.757	0.64
113_A	182_G	0.754	0.64
196_G	199_A	0.753	0.64
101_L	152_V	0.752	0.63
622_F	627_I	0.751	0.63
17_I	54_G	0.751	0.63
519_D	609_E	0.749	0.63
228_E	232_S	0.747	0.63
192_K	196_G	0.747	0.63
19_E	58_R	0.746	0.63
89_H	271_N	0.744	0.63
505_P	508_A	0.741	0.62
168_A	254_A	0.741	0.62
311_E	470_S	0.740	0.62
260_A	264_F	0.740	0.62
128_L	196_G	0.738	0.62
213_A	216_Q	0.736	0.62
479_A	482_S	0.736	0.62
217_P	220_E	0.734	0.62
580_R	605_D	0.733	0.62
688_Q	691_Q	0.733	0.62
688_Q	708_R	0.733	0.62
92_N	274_N	0.732	0.61
85_S	278_V	0.731	0.61
212_K	216_Q	0.731	0.61
570_D	574_A	0.731	0.61
237_K	259_E	0.730	0.61
533_W	665_P	0.730	0.61
109_V	127_R	0.730	0.61
313_P	332_S	0.730	0.61
55_L	58_R	0.729	0.61
235_I	241_A	0.729	0.61
674_W	678_L	0.728	0.61
53_K	61_K	0.727	0.61
218_K	222_L	0.725	0.61
326_G	355_E	0.725	0.61
20_L	42_A	0.724	0.61
313_P	423_V	0.723	0.60
160_A	258_I	0.721	0.60
55_L	105_T	0.721	0.60
516_D	622_F	0.720	0.60
131_P	190_A	0.720	0.60
213_A	218_K	0.719	0.60
199_A	203_Q	0.719	0.60
358_K	361_N	0.718	0.60
248_Y	667_F	0.718	0.60
134_R	485_G	0.718	0.60
369_I	373_K	0.717	0.60
500_N	505_P	0.716	0.60
650_T	653_E	0.716	0.60
53_K	60_N	0.714	0.59
330_Y	334_W	0.713	0.59
113_A	133_L	0.711	0.59
427_N	452_F	0.709	0.59
10_L	18_A	0.709	0.59
225_S	228_E	0.707	0.59
503_L	544_V	0.707	0.59
674_W	683_Y	0.707	0.59
418_V	421_D	0.707	0.59
20_L	57_L	0.703	0.58
430_T	495_P	0.703	0.58
531_F	632_M	0.702	0.58
92_N	148_F	0.701	0.58
513_L	516_D	0.701	0.58
227_I	231_M	0.699	0.58
640_V	706_K	0.699	0.58
14_E	202_R	0.698	0.58
84_L	278_V	0.694	0.57
317_A	384_T	0.693	0.57
63_A	66_V	0.693	0.57
214_K	217_P	0.692	0.57
43_I	101_L	0.687	0.57
356_A	359_L	0.687	0.57
326_G	333_A	0.686	0.56
154_M	163_A	0.685	0.56
130_T	190_A	0.684	0.56
152_V	261_A	0.682	0.56
638_E	645_E	0.681	0.56
109_V	184_V	0.681	0.56
594_E	597_K	0.681	0.56
545_G	549_A	0.679	0.56
340_V	389_G	0.679	0.56
90_F	93_S	0.676	0.55
424_L	440_L	0.676	0.55
522_K	627_I	0.676	0.55
17_I	205_I	0.675	0.55
198_K	201_L	0.674	0.55
260_A	276_S	0.673	0.55
424_L	535_M	0.672	0.55
640_V	680_S	0.672	0.55
422_T	442_R	0.671	0.55
70_I	73_F	0.671	0.55
16_G	52_L	0.671	0.55
137_L	166_I	0.671	0.55
175_A	184_V	0.671	0.55
547_D	581_F	0.669	0.55
140_T	168_A	0.668	0.54
156_R	261_A	0.667	0.54
657_A	660_Y	0.667	0.54
560_F	564_M	0.666	0.54
101_L	105_T	0.665	0.54
18_A	46_L	0.664	0.54
518_A	523_I	0.664	0.54
430_T	548_T	0.664	0.54
82_E	85_S	0.663	0.54
243_T	246_K	0.662	0.54
235_I	239_M	0.661	0.54
676_D	680_S	0.661	0.54
522_K	526_V	0.661	0.54
83_Q	86_Q	0.660	0.54
680_S	683_Y	0.660	0.54
689_Q	692_H	0.659	0.53
211_W	218_K	0.659	0.53
519_D	619_K	0.658	0.53
58_R	110_N	0.658	0.53
132_D	176_D	0.658	0.53
219_L	222_L	0.658	0.53
672_F	676_D	0.657	0.53
140_T	170_G	0.657	0.53
152_V	155_P	0.657	0.53
275_K	279_P	0.656	0.53
109_V	121_V	0.656	0.53
333_A	353_M	0.655	0.53
241_A	244_A	0.655	0.53
31_L	121_V	0.655	0.53
393_V	423_V	0.654	0.53
212_K	218_K	0.652	0.53
308_K	472_E	0.652	0.53
114_L	118_C	0.650	0.52
668_H	677_T	0.649	0.52
364_L	371_G	0.648	0.52
164_L	254_A	0.648	0.52
205_I	210_D	0.648	0.52
678_L	686_M	0.647	0.52
299_V	656_M	0.647	0.52
332_S	484_M	0.646	0.52
280_L	284_N	0.646	0.52
250_A	280_L	0.646	0.52
31_L	120_C	0.645	0.52
609_E	613_A	0.645	0.52
89_H	92_N	0.643	0.52
610_D	614_E	0.643	0.52
17_I	201_L	0.641	0.51
35_T	94_V	0.641	0.51
227_I	230_T	0.640	0.51
502_V	642_C	0.639	0.51
211_W	221_P	0.636	0.51
609_E	619_K	0.636	0.51
352_G	383_P	0.636	0.51
54_G	58_R	0.636	0.51
20_L	105_T	0.635	0.51
38_S	41_E	0.634	0.51
387_Y	546_I	0.634	0.51
11_D	18_A	0.634	0.51
319_L	414_T	0.634	0.51
319_L	342_K	0.633	0.51
680_S	707_A	0.633	0.51
189_K	192_K	0.633	0.51
232_S	236_A	0.633	0.51
387_Y	390_F	0.632	0.50
130_T	193_L	0.630	0.50
21_V	485_G	0.630	0.50
344_I	406_V	0.629	0.50
554_A	577_D	0.629	0.50
451_F	484_M	0.629	0.50
141_K	170_G	0.628	0.50
390_F	513_L	0.628	0.50
680_S	706_K	0.628	0.50
280_L	283_T	0.627	0.50
626_E	693_L	0.627	0.50
579_N	587_L	0.626	0.50
637_N	640_V	0.625	0.50
31_L	65_I	0.624	0.50
164_L	235_I	0.624	0.50
664_F	668_H	0.623	0.49
524_D	671_A	0.623	0.49
324_M	427_N	0.622	0.49
356_A	456_H	0.622	0.49
283_T	549_A	0.622	0.49
330_Y	360_L	0.622	0.49
687_A	690_Y	0.622	0.49
213_A	220_E	0.620	0.49
507_F	511_S	0.620	0.49
162_S	177_Q	0.620	0.49
367_G	371_G	0.620	0.49
626_E	692_H	0.618	0.49
643_L	672_F	0.617	0.49
541_L	589_F	0.616	0.49
604_E	607_A	0.616	0.49
160_A	262_A	0.616	0.49
461_V	488_P	0.616	0.49
632_M	668_H	0.614	0.48
36_V	94_V	0.614	0.48
691_Q	698_E	0.613	0.48
377_V	380_T	0.611	0.48
499_V	540_L	0.611	0.48
151_S	277_F	0.610	0.48
334_W	363_Q	0.609	0.48
425_A	449_M	0.609	0.48
212_K	217_P	0.608	0.48
479_A	483_K	0.606	0.48
648_I	672_F	0.606	0.48
355_E	358_K	0.606	0.48
13_L	51_D	0.606	0.48
381_I	538_A	0.606	0.48
414_T	424_L	0.605	0.47
656_M	659_V	0.605	0.47
681_A	710_N	0.605	0.47
495_P	556_M	0.604	0.47
678_L	682_K	0.603	0.47
347_K	351_L	0.603	0.47
249_P	283_T	0.603	0.47
364_L	378_I	0.602	0.47
200_V	204_A	0.602	0.47
640_V	700_P	0.602	0.47
337_V	380_T	0.602	0.47
261_A	264_F	0.601	0.47
56_L	59_S	0.601	0.47
213_A	219_L	0.600	0.47
578_A	607_A	0.600	0.47
56_L	108_A	0.600	0.47
640_V	703_L	0.600	0.47
342_K	406_V	0.599	0.47
345_N	385_L	0.599	0.47
59_S	65_I	0.599	0.47
459_P	661_G	0.599	0.47
46_L	49_Q	0.598	0.47
434_S	466_G	0.598	0.47
346_D	397_V	0.598	0.47
501_R	638_E	0.595	0.46
332_S	397_V	0.595	0.46
236_A	259_E	0.594	0.46
212_K	221_P	0.594	0.46
241_A	245_G	0.592	0.46
165_E	168_A	0.592	0.46
527_M	628_I	0.592	0.46
373_K	380_T	0.590	0.46
53_K	202_R	0.590	0.46
412_A	441_E	0.589	0.46
32_D	65_I	0.588	0.46
687_A	699_V	0.588	0.46
94_V	98_L	0.587	0.45
46_L	152_V	0.587	0.45
347_K	350_T	0.586	0.45
513_L	622_F	0.586	0.45
603_E	607_A	0.585	0.45
536_G	542_D	0.584	0.45
521_R	525_K	0.584	0.45
396_V	423_V	0.584	0.45
498_F	654_A	0.584	0.45
531_F	668_H	0.583	0.45
176_D	180_K	0.583	0.45
376_G	379_S	0.583	0.45
323_I	453_N	0.583	0.45
261_A	265_G	0.582	0.45
210_D	220_E	0.582	0.45
15_D	19_E	0.582	0.45
252_I	256_K	0.582	0.45
394_D	419_R	0.581	0.45
353_M	381_I	0.581	0.45
99_E	106_I	0.581	0.45
126_Y	204_A	0.581	0.45
624_E	628_I	0.581	0.45
210_D	218_K	0.581	0.45
189_K	196_G	0.580	0.45
234_T	240_V	0.580	0.45
285_E	660_Y	0.580	0.45
110_N	130_T	0.580	0.45
315_Q	393_V	0.580	0.45
271_N	274_N	0.579	0.45
427_N	497_F	0.579	0.45
305_K	308_K	0.579	0.45
209_L	213_A	0.579	0.45
20_L	46_L	0.578	0.44
701_E	704_R	0.577	0.44
332_S	337_V	0.577	0.44
644_E	706_K	0.577	0.44
440_L	445_N	0.576	0.44
321_A	383_P	0.576	0.44
629_A	678_L	0.576	0.44
524_D	604_E	0.576	0.44
562_Q	565_Q	0.576	0.44
19_E	194_V	0.576	0.44
370_D	641_R	0.575	0.44
471_D	649_A	0.575	0.44
240_V	243_T	0.574	0.44
39_L	98_L	0.574	0.44
333_A	377_V	0.573	0.44
505_P	638_E	0.572	0.44
409_A	412_A	0.572	0.44
240_V	251_P	0.572	0.44
249_P	280_L	0.571	0.44
690_Y	693_L	0.570	0.44
349_L	353_M	0.569	0.43
342_K	389_G	0.568	0.43
693_L	697_Y	0.568	0.43
225_S	229_A	0.567	0.43
503_L	531_F	0.566	0.43
634_P	664_F	0.566	0.43
214_K	221_P	0.565	0.43
640_V	676_D	0.565	0.43
393_V	396_V	0.565	0.43
151_S	155_P	0.564	0.43
324_M	452_F	0.564	0.43
544_V	666_P	0.564	0.43
38_S	55_L	0.564	0.43
289_L	293_F	0.563	0.43
313_P	395_I	0.563	0.43
642_C	648_I	0.563	0.43
505_P	552_A	0.562	0.43
428_T	497_F	0.561	0.43
129_A	133_L	0.560	0.42
200_V	207_G	0.559	0.42
173_V	183_L	0.559	0.42
36_V	91_A	0.558	0.42
348_S	351_L	0.558	0.42
397_V	484_M	0.558	0.42
209_L	216_Q	0.558	0.42
506_Y	534_P	0.558	0.42
164_L	168_A	0.556	0.42
47_E	318_V	0.555	0.42
513_L	523_I	0.555	0.42
547_D	585_N	0.555	0.42
304_K	307_T	0.553	0.42
244_A	251_P	0.553	0.42
543_V	583_Q	0.552	0.42
425_A	481_A	0.551	0.42
701_E	709_H	0.550	0.41
364_L	379_S	0.549	0.41
604_E	609_E	0.549	0.41
635_M	662_L	0.548	0.41
232_S	235_I	0.548	0.41
673_R	676_D	0.547	0.41
506_Y	635_M	0.547	0.41
236_A	239_M	0.546	0.41
355_E	362_K	0.546	0.41
30_K	66_V	0.546	0.41
179_L	184_V	0.545	0.41
533_W	538_A	0.545	0.41
515_R	571_A	0.544	0.41
692_H	698_E	0.544	0.41
683_Y	687_A	0.543	0.41
241_A	246_K	0.542	0.41
239_M	243_T	0.542	0.41
326_G	352_G	0.542	0.41
495_P	551_H	0.539	0.40
429_S	458_M	0.538	0.40
546_I	581_F	0.538	0.40
526_V	634_P	0.537	0.40
36_V	89_H	0.537	0.40
140_T	145_M	0.537	0.40
42_A	46_L	0.536	0.40
44_G	47_E	0.536	0.40
13_L	49_Q	0.536	0.40
64_F	107_A	0.536	0.40
388_A	417_K	0.535	0.40
205_I	208_D	0.534	0.40
145_M	253_T	0.534	0.40
607_A	612_L	0.534	0.40
32_D	57_L	0.534	0.40
257_T	260_A	0.532	0.39
507_F	553_Q	0.532	0.39
99_E	105_T	0.531	0.39
299_V	652_A	0.531	0.39
391_D	412_A	0.531	0.39
633_I	690_Y	0.530	0.39
106_I	470_S	0.529	0.39
430_T	500_N	0.529	0.39
161_D	164_L	0.529	0.39
539_Y	543_V	0.528	0.39
54_G	61_K	0.528	0.39
431_I	435_E	0.527	0.39
703_L	707_A	0.527	0.39
87_W	91_A	0.527	0.39
185_D	213_A	0.526	0.39
350_T	357_A	0.525	0.39
313_P	337_V	0.523	0.39
326_G	349_L	0.523	0.39
499_V	503_L	0.522	0.38
63_A	110_N	0.522	0.38
374_L	377_V	0.521	0.38
406_V	551_H	0.521	0.38
618_P	621_D	0.521	0.38
352_G	466_G	0.521	0.38
169_A	243_T	0.520	0.38
271_N	625_E	0.520	0.38
473_T	477_V	0.520	0.38
228_E	233_F	0.519	0.38
46_L	269_A	0.518	0.38
605_D	612_L	0.518	0.38
658_L	662_L	0.518	0.38
540_L	544_V	0.517	0.38
704_R	709_H	0.517	0.38
296_D	459_P	0.517	0.38
173_V	177_Q	0.517	0.38
108_A	580_R	0.516	0.38
113_A	121_V	0.516	0.38
40_G	90_F	0.515	0.38
641_R	700_P	0.515	0.38
106_I	200_V	0.514	0.38
321_A	418_V	0.513	0.37
533_W	552_A	0.512	0.37
401_V	406_V	0.512	0.37
372_L	376_G	0.512	0.37
505_P	634_P	0.512	0.37
126_Y	250_A	0.512	0.37
574_A	614_E	0.511	0.37
131_P	187_V	0.511	0.37
328_I	496_G	0.511	0.37
56_L	197_A	0.511	0.37
329_A	341_M	0.510	0.37
473_T	510_F	0.510	0.37
570_D	573_D	0.510	0.37
31_L	250_A	0.509	0.37
265_G	269_A	0.509	0.37
31_L	35_T	0.509	0.37
416_Q	419_R	0.509	0.37
624_E	627_I	0.508	0.37
31_L	60_N	0.508	0.37
122_L	166_I	0.508	0.37
548_T	552_A	0.508	0.37
602_K	605_D	0.508	0.37
452_F	458_M	0.507	0.37
461_V	464_I	0.506	0.37
391_D	420_Q	0.506	0.37
59_S	110_N	0.506	0.37
298_Y	650_T	0.506	0.37
362_K	365_E	0.505	0.37
204_A	211_W	0.505	0.37
68_A	584_K	0.505	0.37
525_K	528_E	0.505	0.37
580_R	592_Y	0.505	0.37
179_L	186_G	0.505	0.37
324_M	497_F	0.504	0.37
355_E	359_L	0.504	0.37
73_F	290_V	0.503	0.36
288_A	677_T	0.502	0.36
126_Y	635_M	0.502	0.36
636_V	678_L	0.502	0.36
305_K	479_A	0.502	0.36
681_A	684_L	0.501	0.36
135_I	174_G	0.501	0.36
77_F	83_Q	0.501	0.36
452_F	497_F	0.501	0.36
92_N	430_T	0.501	0.36
491_V	649_A	0.500	0.36
326_G	385_L	0.500	0.36

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1wdkA	2	0.9739	100	0.294	Contact Map
2wtbA	1	0.915	100	0.313	Contact Map
3zwcA	1	0.9671	100	0.34	Contact Map
4b3hA	1	0.952	100	0.342	Contact Map
1zcjA	1	0.6036	100	0.578	Contact Map
3k6jA	1	0.5748	100	0.596	Contact Map
3mogA	3	0.546	100	0.66	Contact Map
4j0eA	2	0.3964	100	0.735	Contact Map
1f0yA	2	0.3896	100	0.744	Contact Map
4r1nA	2	0.3855	100	0.746	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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