GREMLIN Database
SPEA - Biosynthetic arginine decarboxylase
UniProt: P21170 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10959
Length: 658 (621)
Sequences: 706 (416)
Seq/√Len: 16.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
216_V264_D8.4871.00
56_H71_D6.3161.00
512_G515_Q5.9761.00
118_G356_T5.2421.00
204_A256_T5.2331.00
553_D556_N5.0251.00
307_F343_I4.4381.00
267_Q305_Q4.2681.00
195_L206_V4.1941.00
188_K637_L4.1821.00
348_E354_H4.0501.00
57_I508_L3.9791.00
48_Y98_H3.8851.00
333_N337_N3.7781.00
483_D519_R3.5931.00
343_I357_V3.5921.00
90_F373_V3.5911.00
221_V253_L3.5801.00
124_Y135_I3.4220.99
207_L262_R3.3290.99
197_I206_V3.2950.99
521_A549_M3.1470.99
518_E551_E3.0220.99
340_I357_V2.9520.98
338_N423_D2.9260.98
571_I613_V2.8880.98
197_I253_L2.8630.98
180_I206_V2.7700.97
539_D543_I2.7440.97
395_P399_Q2.6690.97
73_A77_K2.6620.97
263_L302_V2.5930.96
52_N71_D2.5240.96
298_H353_P2.5160.95
30_Q35_M2.5160.95
512_G550_P2.5020.95
581_D612_Y2.4500.95
160_A620_L2.4460.95
288_R345_D2.4190.94
216_V265_S2.4130.94
550_P558_P2.3360.93
79_R88_A2.3260.93
183_A195_L2.2950.93
539_D544_A2.2790.92
376_I487_V2.2750.92
187_E218_R2.2600.92
52_N56_H2.2570.92
50_D58_S2.2560.92
132_R136_E2.2450.92
434_G439_I2.2290.91
606_V648_G2.2260.91
35_M38_T2.1830.91
441_S444_E2.1650.90
32_A51_V2.1120.89
334_E423_D2.1040.89
30_Q38_T2.0820.88
309_V359_T2.0570.88
287_V339_I2.0250.87
170_V358_I2.0080.86
431_I448_A2.0050.86
73_A511_E1.9890.86
284_A338_N1.9870.86
51_V630_K1.9630.85
216_V262_R1.9590.85
570_E581_D1.9540.85
262_R265_S1.9050.83
648_G656_E1.9040.83
280_I423_D1.8990.83
49_Y59_V1.8990.83
117_N354_H1.8430.81
223_A269_L1.8390.81
60_C69_R1.8260.80
253_L256_T1.8170.80
210_A215_V1.7910.79
581_D604_D1.7860.79
223_A250_V1.7820.79
30_Q517_P1.7800.79
281_R651_G1.7800.79
76_V559_M1.7760.79
268_L308_D1.7640.78
493_Q581_D1.7560.78
314_G328_V1.7540.78
241_S273_L1.7460.77
191_H627_Q1.7400.77
539_D542_G1.7340.77
209_E212_R1.7190.76
318_E326_C1.7160.76
482_A546_T1.7130.76
229_G237_G1.7060.76
485_M550_P1.6970.75
309_V339_I1.6910.75
196_V308_D1.6860.75
255_E261_G1.6670.74
394_A398_L1.6660.74
211_E260_A1.6640.74
394_A447_W1.6570.73
36_L50_D1.6520.73
31_E34_K1.6480.73
71_D75_L1.6210.72
194_Y306_C1.6120.71
307_F357_V1.5970.71
495_M572_L1.5850.70
197_I219_L1.5730.69
45_G59_V1.5710.69
396_R399_Q1.5680.69
395_P398_L1.5630.69
177_R208_D1.5630.69
510_L561_G1.5500.68
63_P67_E1.5480.68
207_L260_A1.5450.68
104_N122_L1.5330.67
249_Q284_A1.5330.67
603_G652_Y1.5320.67
257_L266_L1.5310.67
255_E443_Q1.5290.67
192_K218_R1.5260.67
500_G534_I1.5210.67
170_V196_V1.5170.66
374_S562_F1.5160.66
607_A617_P1.5070.66
170_V523_L1.4950.65
468_R542_G1.4830.65
419_E423_D1.4730.64
287_V343_I1.4660.64
223_A339_I1.4660.64
315_V564_M1.4600.63
180_I403_E1.4590.63
395_P444_E1.4540.63
229_G560_L1.4490.63
203_I207_L1.4380.62
373_V491_L1.4280.62
507_V534_I1.4210.61
515_Q550_P1.4200.61
128_V489_F1.4190.61
606_V651_G1.4090.61
385_T521_A1.4070.60
391_A394_A1.4050.60
177_R209_E1.4010.60
153_A609_M1.3930.60
463_L479_E1.3850.59
71_D74_Q1.3840.59
236_S286_G1.3800.59
451_L455_M1.3800.59
99_R328_V1.3720.58
90_F651_G1.3690.58
258_R263_L1.3650.58
485_M552_Y1.3640.58
203_I260_A1.3630.58
255_E258_R1.3590.58
185_I641_F1.3490.57
41_I57_I1.3460.57
431_I440_F1.3400.57
379_V552_Y1.3350.56
320_T504_L1.3350.56
111_R219_L1.3340.56
403_E591_P1.3320.56
188_K215_V1.3310.56
511_E550_P1.3240.56
570_E584_A1.3230.56
53_E212_R1.3220.56
35_M186_G1.3220.56
324_S542_G1.3190.55
324_S540_G1.3190.55
77_K80_E1.3150.55
261_G373_V1.3120.55
170_V308_D1.3050.55
586_D601_D1.3030.54
318_E324_S1.3030.54
332_L357_V1.2960.54
415_R542_G1.2900.54
611_Q617_P1.2890.54
491_L526_I1.2840.53
218_R267_Q1.2800.53
84_Q643_E1.2770.53
126_I157_A1.2730.53
242_K530_S1.2650.52
596_E636_E1.2580.52
97_Q137_S1.2480.51
206_V435_Y1.2470.51
544_A548_P1.2460.51
434_G444_E1.2380.51
486_Y584_A1.2360.50
280_I422_H1.2340.50
624_F645_F1.2310.50
255_E259_E1.2280.50
281_R415_R1.2200.50
254_V263_L1.1970.48
124_Y157_A1.1940.48
186_G193_V1.1930.48
128_V574_N1.1880.48
646_E650_Y1.1880.48
612_Y652_Y1.1870.48
38_T517_P1.1870.48
388_T396_R1.1820.47
353_P371_V1.1820.47
32_A70_V1.1820.47
483_D489_F1.1790.47
605_T608_D1.1710.47
189_M223_A1.1690.46
295_V346_A1.1660.46
82_Q629_K1.1660.46
517_P550_P1.1610.46
138_L552_Y1.1550.46
442_L500_G1.1530.46
402_W406_Q1.1510.45
254_V297_L1.1500.45
368_H579_F1.1460.45
424_S455_M1.1390.45
131_H582_T1.1370.45
470_H475_D1.1360.45
110_A336_A1.1320.44
508_L513_L1.1310.44
214_N398_L1.1290.44
162_A444_E1.1290.44
32_A35_M1.1260.44
56_H451_L1.1250.44
603_G653_T1.1240.44
189_M491_L1.1210.44
590_F596_E1.1200.44
512_G558_P1.1200.44
113_S605_T1.1180.44
570_E582_T1.1150.43
45_G359_T1.1120.43
249_Q286_G1.1110.43
103_I332_L1.1090.43
424_S500_G1.1060.43
521_A636_E1.0990.42
137_S609_M1.0970.42
604_D612_Y1.0930.42
261_G351_G1.0920.42
41_I203_I1.0890.42
242_K369_H1.0850.42
118_G252_Q1.0810.41
158_V486_Y1.0780.41
393_D399_Q1.0750.41
142_G550_P1.0700.41
375_N557_P1.0680.41
123_V145_L1.0660.41
320_T331_G1.0660.41
158_V320_T1.0590.40
223_A293_F1.0580.40
284_A437_S1.0570.40
258_R267_Q1.0570.40
298_H305_Q1.0560.40
485_M558_P1.0550.40
634_D637_L1.0510.40
433_I510_L1.0490.40
555_E592_D1.0480.39
581_D613_V1.0470.39
74_Q590_F1.0450.39
287_V342_A1.0450.39
373_V433_I1.0450.39
90_F179_Y1.0400.39
157_A237_G1.0390.39
157_A369_H1.0380.39
98_H102_S1.0360.39
192_K307_F1.0320.39
390_P398_L1.0260.38
117_N348_E1.0260.38
273_L286_G1.0250.38
309_V347_C1.0240.38
291_A294_Y1.0230.38
322_S539_D1.0230.38
109_R333_N1.0230.38
103_I122_L1.0190.38
37_R197_I1.0170.38
606_V613_V1.0160.38
266_L409_H1.0130.38
188_K214_N1.0130.38
112_E264_D1.0120.37
226_A445_R1.0110.37
228_Q236_S1.0110.37
156_M443_Q1.0100.37
128_V487_V1.0080.37
540_G544_A1.0070.37
56_H73_A1.0070.37
430_D434_G1.0070.37
261_G515_Q1.0040.37
371_V601_D1.0020.37
53_E250_V1.0010.37
181_R209_E1.0000.37
259_E299_K1.0000.37
242_K655_L0.9990.37
466_Q470_H0.9950.37
35_M341_W0.9940.36
515_Q552_Y0.9930.36
124_Y214_N0.9910.36
487_V500_G0.9910.36
496_P572_L0.9910.36
136_E561_G0.9860.36
598_E637_L0.9840.36
159_L186_G0.9840.36
212_R514_D0.9810.36
338_N422_H0.9790.36
241_S546_T0.9790.36
496_P582_T0.9760.35
112_E115_G0.9760.35
523_L543_I0.9740.35
88_A293_F0.9730.35
390_P395_P0.9710.35
476_E482_A0.9690.35
314_G588_F0.9690.35
246_A605_T0.9690.35
483_D656_E0.9680.35
504_L538_I0.9680.35
103_I169_I0.9650.35
267_Q279_N0.9620.35
131_H570_E0.9610.35
491_L636_E0.9610.35
565_V570_E0.9600.35
315_V421_L0.9590.35
475_D542_G0.9590.35
314_G352_L0.9580.35
73_A526_I0.9490.34
389_A393_D0.9480.34
491_L562_F0.9460.34
304_I628_V0.9450.34
122_L343_I0.9440.34
143_E258_R0.9440.34
495_M562_F0.9430.34
579_F655_L0.9420.34
396_R400_S0.9410.34
450_Q616_D0.9360.33
625_R629_K0.9350.33
79_R521_A0.9340.33
110_A221_V0.9340.33
56_H75_L0.9320.33
138_L246_A0.9280.33
261_G296_E0.9270.33
139_I523_L0.9270.33
219_L616_D0.9270.33
206_V219_L0.9230.33
267_Q303_N0.9210.33
226_A491_L0.9210.33
269_L286_G0.9170.32
237_G278_A0.9160.32
38_T516_V0.9110.32
61_P95_I0.9100.32
458_E462_Q0.9080.32
169_I224_R0.9080.32
334_E422_H0.9070.32
256_T260_A0.9060.32
80_E375_N0.9050.32
124_Y366_T0.9050.32
199_K237_G0.9010.32
524_L584_A0.9000.31
296_E299_K0.8980.31
79_R587_V0.8980.31
534_I643_E0.8980.31
92_F242_K0.8980.31
211_E262_R0.8960.31
88_A606_V0.8950.31
357_V469_A0.8940.31
296_E350_N0.8940.31
502_D612_Y0.8930.31
341_W526_I0.8930.31
79_R357_V0.8900.31
53_E69_R0.8900.31
280_I338_N0.8890.31
574_N651_G0.8890.31
336_A347_C0.8880.31
337_N422_H0.8880.31
195_L623_Q0.8860.31
113_S472_P0.8840.31
388_T391_A0.8820.31
64_D67_E0.8820.31
112_E502_D0.8810.31
452_Y523_L0.8800.30
299_K510_L0.8790.30
215_V626_D0.8780.30
264_D596_E0.8760.30
463_L469_A0.8760.30
431_I495_M0.8740.30
74_Q299_K0.8720.30
309_V378_G0.8710.30
131_H581_D0.8700.30
136_E210_A0.8700.30
277_M421_L0.8690.30
280_I334_E0.8690.30
292_R448_A0.8680.30
246_A507_V0.8670.30
463_L468_R0.8670.30
394_A402_W0.8670.30
221_V504_L0.8660.30
511_E526_I0.8660.30
142_G500_G0.8660.30
398_L459_V0.8650.30
500_G540_G0.8650.30
104_N108_K0.8650.30
574_N613_V0.8640.30
179_Y655_L0.8600.29
338_N419_E0.8570.29
366_T484_K0.8570.29
90_F153_A0.8560.29
97_Q135_I0.8550.29
489_F656_E0.8540.29
196_V268_L0.8540.29
179_Y445_R0.8530.29
142_G633_L0.8530.29
452_Y456_C0.8510.29
210_A461_K0.8510.29
278_A366_T0.8500.29
553_D632_D0.8500.29
394_A399_Q0.8500.29
98_H507_V0.8480.29
625_R646_E0.8460.29
203_I652_Y0.8440.29
52_N58_S0.8440.29
316_D319_G0.8430.29
299_K398_L0.8430.29
89_L95_I0.8430.29
455_M507_V0.8410.29
468_R475_D0.8390.28
324_S543_I0.8370.28
314_G325_D0.8360.28
322_S540_G0.8350.28
90_F102_S0.8330.28
184_L215_V0.8320.28
294_Y298_H0.8300.28
57_I331_G0.8290.28
534_I585_V0.8260.28
337_N423_D0.8250.28
261_G441_S0.8240.28
207_L339_I0.8220.28
77_K81_A0.8220.28
374_S377_I0.8200.28
260_A518_E0.8170.27
344_G376_I0.8170.27
298_H352_L0.8160.27
139_I502_D0.8150.27
486_Y581_D0.8150.27
168_V358_I0.8120.27
608_D614_Q0.8120.27
606_V656_E0.8110.27
390_P556_N0.8090.27
120_Y359_T0.8090.27
75_L585_V0.8080.27
614_Q645_F0.8040.27
105_A303_N0.8030.27
486_Y582_T0.8030.27
184_L314_G0.8030.27
241_S582_T0.8020.27
339_I342_A0.8020.27
227_S430_D0.8020.27
267_Q523_L0.8020.27
561_G587_V0.7990.27
157_A648_G0.7990.27
284_A422_H0.7980.27
131_H575_M0.7970.26
179_Y250_V0.7970.26
496_P604_D0.7960.26
279_N323_Q0.7960.26
398_L514_D0.7950.26
221_V266_L0.7940.26
57_I472_P0.7900.26
100_L104_N0.7900.26
383_E457_H0.7870.26
609_M614_Q0.7850.26
153_A308_D0.7850.26
106_A332_L0.7840.26
523_L601_D0.7830.26
34_K114_Y0.7820.26
103_I345_D0.7820.26
292_R296_E0.7810.26
124_Y487_V0.7790.26
194_Y560_L0.7780.26
604_D611_Q0.7780.26
100_L459_V0.7760.26
184_L209_E0.7750.25
390_P399_Q0.7750.25
169_I277_M0.7740.25
169_I223_A0.7730.25
132_R229_G0.7720.25
321_R458_E0.7700.25
45_G56_H0.7660.25
605_T620_L0.7650.25
470_H473_I0.7650.25
487_V562_F0.7650.25
601_D609_M0.7620.25
72_L371_V0.7620.25
470_H537_Y0.7620.25
135_I211_E0.7610.25
204_A208_D0.7610.25
31_E350_N0.7610.25
515_Q558_P0.7600.25
389_A518_E0.7600.25
407_E441_S0.7590.25
57_I88_A0.7560.25
123_V358_I0.7560.25
251_L321_R0.7550.25
300_L443_Q0.7550.25
340_I583_E0.7550.25
187_E193_V0.7540.25
445_R505_F0.7520.24
50_D476_E0.7520.24
242_K336_A0.7520.24
392_E514_D0.7520.24
234_Q487_V0.7520.24
219_L266_L0.7500.24
89_L582_T0.7490.24
186_G648_G0.7490.24
138_L441_S0.7490.24
169_I194_Y0.7460.24
538_I542_G0.7450.24
403_E407_E0.7450.24
79_R625_R0.7450.24
290_S550_P0.7440.24
421_L456_C0.7440.24
56_H526_I0.7430.24
31_E510_L0.7430.24
586_D609_M0.7430.24
235_S495_M0.7430.24
651_G656_E0.7420.24
236_S561_G0.7410.24
229_G530_S0.7410.24
122_L537_Y0.7400.24
536_H541_D0.7390.24
185_I644_E0.7380.24
390_P402_W0.7360.24
122_L418_R0.7360.24
336_A530_S0.7330.24
390_P394_A0.7320.24
104_N142_G0.7320.24
397_A400_S0.7310.24
131_H486_Y0.7290.23
287_V307_F0.7290.23
249_Q282_D0.7290.23
258_R261_G0.7290.23
449_E493_Q0.7270.23
591_P636_E0.7270.23
203_I219_L0.7260.23
591_P640_Q0.7250.23
296_E300_L0.7240.23
170_V215_V0.7230.23
302_V445_R0.7230.23
255_E365_V0.7220.23
540_G543_I0.7220.23
498_A534_I0.7220.23
379_V587_V0.7210.23
521_A543_I0.7210.23
507_V626_D0.7210.23
421_L584_A0.7200.23
258_R393_D0.7180.23
180_I226_A0.7170.23
197_I358_I0.7170.23
77_K180_I0.7170.23
633_L640_Q0.7160.23
351_G373_V0.7140.23
401_M424_S0.7130.23
239_E618_K0.7130.23
70_V630_K0.7120.23
144_P634_D0.7100.23
75_L333_N0.7090.23
340_I352_L0.7080.23
424_S459_V0.7080.23
170_V640_Q0.7070.23
171_C505_F0.7060.22
200_M514_D0.7050.22
118_G373_V0.7040.22
53_E388_T0.7040.22
227_S307_F0.7030.22
97_Q241_S0.7010.22
181_R232_K0.7010.22
134_V367_A0.7010.22
209_E537_Y0.7000.22
210_A562_F0.6990.22
31_E126_I0.6980.22
391_A398_L0.6960.22
442_L534_I0.6940.22
105_A266_L0.6930.22
517_P558_P0.6920.22
339_I470_H0.6910.22
92_F371_V0.6890.22
493_Q526_I0.6880.22
284_A423_D0.6860.22
255_E502_D0.6860.22
314_G586_D0.6860.22
178_E656_E0.6850.22
35_M511_E0.6830.22
33_S587_V0.6830.22
99_R120_Y0.6830.22
180_I211_E0.6820.22
128_V493_Q0.6820.22
329_N419_E0.6820.22
601_D608_D0.6810.21
128_V334_E0.6810.21
254_V302_V0.6790.21
543_I546_T0.6770.21
145_L524_L0.6770.21
67_E248_T0.6760.21
35_M180_I0.6760.21
291_A400_S0.6760.21
141_S570_E0.6760.21
388_T630_K0.6750.21
486_Y570_E0.6750.21
442_L498_A0.6730.21
224_R230_S0.6730.21
139_I421_L0.6720.21
88_A351_G0.6710.21
295_V352_L0.6710.21
253_L269_L0.6710.21
157_A199_K0.6670.21
299_K443_Q0.6670.21
315_V519_R0.6670.21
340_I358_I0.6650.21
89_L149_A0.6640.21
562_F587_V0.6640.21
511_E523_L0.6620.21
549_M640_Q0.6590.21
500_G550_P0.6590.21
613_V648_G0.6580.21
119_D203_I0.6580.21
75_L141_S0.6580.21
213_L300_L0.6570.21
575_M581_D0.6550.20
128_V234_Q0.6540.20
131_H574_N0.6530.20
36_L219_L0.6530.20
293_F321_R0.6530.20
319_G580_G0.6520.20
214_N250_V0.6500.20
385_T591_P0.6500.20
277_M514_D0.6500.20
571_I581_D0.6490.20
158_V304_I0.6470.20
621_L646_E0.6460.20
485_M544_A0.6460.20
334_E338_N0.6460.20
258_R389_A0.6440.20
247_A303_N0.6440.20
404_T408_M0.6440.20
581_D584_A0.6430.20
388_T474_I0.6430.20
419_E422_H0.6420.20
258_R332_L0.6410.20
64_D138_L0.6410.20
280_I493_Q0.6410.20
324_S539_D0.6400.20
37_R322_S0.6400.20
331_G417_L0.6390.20
500_G614_Q0.6380.20
80_E624_F0.6380.20
239_E321_R0.6370.20
359_T432_H0.6370.20
160_A365_V0.6370.20
169_I575_M0.6360.20
376_I551_E0.6360.20
160_A452_Y0.6350.20
99_R295_V0.6350.20
142_G512_G0.6340.20
251_L449_E0.6340.20
487_V523_L0.6320.20
145_L287_V0.6320.20
567_A578_L0.6300.20
357_V389_A0.6300.20
133_R597_V0.6300.20
485_M500_G0.6290.19
520_R546_T0.6280.19
101_R141_S0.6280.19
421_L458_E0.6280.19
90_F609_M0.6280.19
398_L502_D0.6270.19
218_R550_P0.6240.19
159_L446_A0.6220.19
477_L605_T0.6210.19
191_H249_Q0.6190.19
477_L620_L0.6180.19
88_A609_M0.6180.19
242_K271_F0.6180.19
199_K369_H0.6170.19
83_G373_V0.6160.19
49_Y294_Y0.6160.19
515_Q553_D0.6150.19
178_E651_G0.6140.19
486_Y604_D0.6140.19
535_D652_Y0.6140.19
132_R284_A0.6140.19
400_S418_R0.6130.19
237_G369_H0.6130.19
224_R380_E0.6120.19
210_A637_L0.6120.19
387_P441_S0.6120.19
196_V574_N0.6120.19
189_M203_I0.6120.19
184_L565_V0.6110.19
171_C225_L0.6110.19
484_K629_K0.6100.19
469_A475_D0.6100.19
119_D356_T0.6090.19
246_A487_V0.6080.19
370_T614_Q0.6080.19
476_E560_L0.6060.19
41_I534_I0.6060.19
145_L365_V0.6050.19
454_S602_E0.6050.19
165_T339_I0.6040.19
97_Q124_Y0.6030.19
75_L621_L0.6020.18
203_I265_S0.6010.18
82_Q608_D0.6010.18
521_A557_P0.6000.18
131_H638_Q0.5990.18
373_V465_P0.5990.18
446_A463_L0.5980.18
82_Q377_I0.5980.18
69_R83_G0.5950.18
405_W454_S0.5940.18
122_L422_H0.5930.18
552_Y637_L0.5930.18
570_E593_G0.5920.18
84_Q340_I0.5910.18
29_S33_S0.5900.18
104_N306_C0.5880.18
71_D526_I0.5880.18
96_L134_V0.5870.18
521_A565_V0.5870.18
286_G320_T0.5860.18
370_T473_I0.5860.18
408_M433_I0.5850.18
258_R514_D0.5850.18
604_D629_K0.5850.18
53_E392_E0.5850.18
204_A236_S0.5840.18
170_V464_D0.5840.18
484_K524_L0.5830.18
361_S365_V0.5830.18
178_E522_V0.5830.18
571_I574_N0.5830.18
51_V296_E0.5820.18
158_V199_K0.5820.18
207_L210_A0.5820.18
191_H215_V0.5820.18
526_I586_D0.5810.18
184_L342_A0.5810.18
131_H584_A0.5800.18
249_Q271_F0.5800.18
229_G422_H0.5800.18
242_K524_L0.5800.18
99_R368_H0.5790.18
167_S435_Y0.5790.18
34_K59_V0.5780.18
636_E641_F0.5770.18
287_V599_L0.5770.18
315_V367_A0.5770.18
331_G487_V0.5750.18
194_Y218_R0.5750.18
250_V257_L0.5750.18
108_K353_P0.5750.18
307_F524_L0.5750.18
536_H539_D0.5750.18
31_E269_L0.5740.18
106_A339_I0.5740.18
400_S403_E0.5740.18
60_C277_M0.5740.18
251_L444_E0.5730.17
279_N430_D0.5730.17
145_L378_G0.5730.17
574_N581_D0.5720.17
280_I284_A0.5720.17
84_Q88_A0.5720.17
207_L227_S0.5710.17
69_R111_R0.5710.17
53_E607_A0.5710.17
32_A36_L0.5700.17
138_L388_T0.5700.17
288_R435_Y0.5690.17
171_C319_G0.5690.17
236_S646_E0.5690.17
520_R548_P0.5670.17
250_V264_D0.5670.17
597_V600_S0.5650.17
77_K211_E0.5650.17
357_V640_Q0.5630.17
489_F651_G0.5620.17
193_V359_T0.5620.17
174_Y184_L0.5610.17
290_S526_I0.5610.17
181_R644_E0.5610.17
99_R571_I0.5600.17
68_A109_R0.5600.17
138_L339_I0.5600.17
498_A507_V0.5590.17
89_L237_G0.5590.17
209_E565_V0.5590.17
648_G651_G0.5580.17
39_Y55_G0.5580.17
159_L406_Q0.5580.17
390_P560_L0.5580.17
207_L254_V0.5580.17
103_I340_I0.5580.17
169_I199_K0.5570.17
32_A161_H0.5570.17
320_T324_S0.5570.17
486_Y625_R0.5570.17
189_M538_I0.5560.17
94_Q153_A0.5550.17
101_R375_N0.5550.17
200_M253_L0.5550.17
170_V315_V0.5540.17
228_Q498_A0.5530.17
89_L124_Y0.5520.17
430_D623_Q0.5520.17
570_E612_Y0.5520.17
112_E458_E0.5510.17
31_E626_D0.5510.17
211_E258_R0.5500.17
524_L615_L0.5490.17
76_V278_A0.5490.17
88_A652_Y0.5480.17
491_L656_E0.5480.17
187_E216_V0.5470.17
122_L538_I0.5470.17
257_L547_M0.5450.17
327_S335_Y0.5440.17
373_V515_Q0.5430.16
357_V642_L0.5430.16
137_S574_N0.5430.16
249_Q655_L0.5420.16
304_I486_Y0.5410.16
338_N453_L0.5410.16
53_E246_A0.5410.16
400_S631_T0.5410.16
126_I226_A0.5410.16
89_L570_E0.5410.16
426_M432_H0.5400.16
600_S611_Q0.5400.16
305_Q356_T0.5400.16
235_S627_Q0.5400.16
208_D221_V0.5390.16
109_R210_A0.5380.16
117_N393_D0.5380.16
253_L318_E0.5380.16
178_E249_Q0.5380.16
391_A514_D0.5380.16
45_G69_R0.5380.16
463_L474_I0.5370.16
65_V300_L0.5370.16
200_M252_Q0.5370.16
168_V537_Y0.5360.16
252_Q259_E0.5360.16
601_D614_Q0.5360.16
586_D614_Q0.5360.16
346_A514_D0.5350.16
151_S579_F0.5350.16
293_F365_V0.5340.16
334_E526_I0.5330.16
169_I191_H0.5330.16
485_M549_M0.5330.16
51_V83_G0.5330.16
416_S549_M0.5320.16
290_S512_G0.5310.16
334_E341_W0.5310.16
131_H496_P0.5310.16
575_M609_M0.5300.16
566_G577_N0.5300.16
568_Y577_N0.5300.16
92_F309_V0.5290.16
292_R604_D0.5290.16
418_R422_H0.5280.16
70_V589_V0.5280.16
510_L544_A0.5280.16
204_A376_I0.5280.16
179_Y347_C0.5280.16
199_K368_H0.5270.16
255_E575_M0.5270.16
167_S197_I0.5270.16
44_W55_G0.5260.16
111_R552_Y0.5250.16
86_L457_H0.5250.16
36_L42_A0.5250.16
149_A281_R0.5240.16
523_L534_I0.5240.16
609_M653_T0.5240.16
224_R237_G0.5230.16
426_M430_D0.5230.16
32_A514_D0.5230.16
358_I498_A0.5230.16
51_V649_L0.5220.16
343_I356_T0.5220.16
189_M552_Y0.5220.16
124_Y459_V0.5210.16
385_T390_P0.5190.16
137_S241_S0.5190.16
179_Y316_D0.5190.16
261_G358_I0.5190.16
46_N75_L0.5180.16
394_A406_Q0.5180.16
582_T612_Y0.5170.16
85_R583_E0.5170.16
431_I519_R0.5170.16
476_E480_R0.5170.16
68_A74_Q0.5170.16
367_A565_V0.5160.16
241_S606_V0.5150.16
178_E208_D0.5150.16
284_A287_V0.5150.16
621_L650_Y0.5150.16
271_F318_E0.5150.16
105_A109_R0.5140.16
389_A447_W0.5140.16
103_I250_V0.5120.15
440_F454_S0.5120.15
159_L193_V0.5120.15
30_Q34_K0.5120.15
364_A523_L0.5120.15
377_I484_K0.5120.15
35_M52_N0.5110.15
287_V376_I0.5100.15
607_A650_Y0.5100.15
42_A607_A0.5100.15
581_D652_Y0.5100.15
188_K551_E0.5090.15
472_P479_E0.5060.15
103_I315_V0.5060.15
181_R366_T0.5050.15
166_R656_E0.5040.15
295_V350_N0.5040.15
318_E338_N0.5030.15
178_E296_E0.5030.15
72_L570_E0.5020.15
464_D540_G0.5020.15
131_H604_D0.5020.15
280_I419_E0.5020.15
369_H655_L0.5020.15
402_W405_W0.5010.15
95_I619_T0.5010.15
74_Q78_T0.5010.15
230_S282_D0.5010.15
523_L620_L0.5010.15
299_K395_P0.5000.15
618_K639_Q0.5000.15
300_L435_Y0.5000.15
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3nzqA 2 0.9498 100 0.388 Contact Map
3n2oA 2 0.9498 100 0.398 Contact Map
3nzpA 2 0.8754 100 0.472 Contact Map
1twiA 4 0.652 100 0.842 Contact Map
3btnA 2 0.5912 100 0.844 Contact Map
3n2bA 2 0.6383 100 0.844 Contact Map
2o0tA 2 0.6596 100 0.849 Contact Map
2j66A 2 0.5881 100 0.858 Contact Map
1knwA 2 0.6246 100 0.858 Contact Map
2qghA 2 0.5957 100 0.862 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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