PARE - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

PARE - DNA topoisomerase 4 subunit B

UniProt:	P20083	Sequences: MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSVDEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHPEEGVPAVELILCRLHAGGKFSNKNYQFSGGLHGVGISVVNALSKRVEVNVRRDGQVYNIAFENGEKVQDLQVVGTCGKRNTGTSVHFWPDETFFDSPRFSVSRLTHVLKAKAVLCPGVEITFKDEINNTEQRWCYQDGLNDYLAEAVNGLPTLPEKPFIGNFAGDTEAVDWALLWLPEGGELLTESYVNLIPTMQGGTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVLSVKMQDPQFAGQTKERLSSRQCAAFVSGVVKDAFILWLNQNVQAAELLAEMAISSAQRRMRAAKKVVRKKLTSGPALPGKLADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEVSSDEVLASQEVHDISVAIGIDPDSDDLSQLRYGKICILADADSDGLHIATLLCALFVKHFRALVKHGHVYVALPPLYRIDLGKEVYYALTEEEKEGVLEQLKRKKGKPNVQRFKGLGEMNPMQLRETTLDPNTRRLVQLTIDDEDDQRTDAMMDMLLAKKRSEDRRNWLQEKGDMAEIEV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10687
Length:	630 (615)
Sequences:	4796 (2020)
Seq/√Len:	81.5

ECOLI - PARE GYRB
BACSU - GYRB PARE
HALSA - Q9HR30

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
53_K	70_D	6.509	1.00
135_Q	152_V	4.386	1.00
39_V	116_I	4.305	1.00
203_K	210_E	4.035	1.00
124_K	168_W	3.966	1.00
60_H	66_E	3.741	1.00
127_E	140_A	3.709	1.00
169_P	179_F	3.568	1.00
538_A	547_V	3.502	1.00
142_E	147_V	3.402	1.00
125_R	168_W	3.294	1.00
131_R	160_N	3.170	1.00
199_E	212_R	3.136	1.00
68_I	164_S	3.122	1.00
406_A	411_R	3.074	1.00
580_D	583_T	2.994	1.00
483_G	518_H	2.955	1.00
87_V	128_V	2.919	1.00
7_A	77_D	2.905	1.00
127_E	138_N	2.847	1.00
54_R	199_E	2.828	1.00
91_L	165_V	2.789	1.00
87_V	150_L	2.777	1.00
138_N	151_Q	2.700	1.00
82_E	89_L	2.676	1.00
36_G	184_L	2.650	1.00
192_A	215_Y	2.649	1.00
135_Q	155_T	2.647	1.00
125_R	140_A	2.641	1.00
60_H	205_E	2.622	1.00
480_L	518_H	2.618	1.00
296_E	306_K	2.615	1.00
408_D	411_R	2.588	1.00
66_E	166_H	2.549	1.00
129_N	164_S	2.545	1.00
196_P	241_N	2.540	1.00
128_V	165_V	2.500	1.00
101_S	104_N	2.500	1.00
54_R	70_D	2.479	1.00
60_H	166_H	2.474	1.00
148_Q	151_Q	2.411	1.00
87_V	130_V	2.378	1.00
76_V	137_Y	2.363	1.00
414_L	468_I	2.352	1.00
56_D	201_T	2.351	1.00
622_K	625_M	2.347	1.00
56_D	68_I	2.335	1.00
129_N	138_N	2.333	1.00
61_A	205_E	2.281	1.00
137_Y	152_V	2.275	1.00
36_G	65_L	2.266	1.00
59_L	65_L	2.258	1.00
124_K	171_E	2.240	1.00
527_Y	541_E	2.213	1.00
409_L	483_G	2.210	1.00
181_V	211_Q	2.198	1.00
84_V	88_E	2.187	1.00
199_E	214_C	2.179	1.00
129_N	136_V	2.170	1.00
44_V	198_V	2.149	1.00
57_V	188_L	2.125	1.00
7_A	86_A	2.123	1.00
464_I	468_I	2.119	1.00
523_L	587_V	2.116	1.00
52_A	70_D	2.088	1.00
127_E	166_H	2.080	1.00
251_W	320_L	2.073	1.00
617_N	621_E	2.072	1.00
14_T	81_E	2.072	1.00
143_N	172_T	2.069	1.00
290_A	351_K	2.068	1.00
511_R	515_K	2.061	1.00
512_A	515_K	2.059	1.00
293_E	297_Y	2.055	1.00
275_Q	335_E	2.047	1.00
530_D	535_V	2.040	1.00
66_E	164_S	2.029	1.00
152_V	155_T	2.023	1.00
181_V	202_F	2.015	1.00
131_R	136_V	1.991	1.00
486_C	586_L	1.979	1.00
221_D	224_A	1.960	1.00
129_N	166_H	1.950	1.00
239_I	250_D	1.947	1.00
405_T	432_R	1.945	1.00
60_H	64_S	1.936	1.00
140_A	147_V	1.912	1.00
307_L	372_A	1.909	1.00
74_M	90_I	1.908	1.00
156_C	160_N	1.901	1.00
402_A	427_K	1.896	1.00
139_I	146_K	1.869	1.00
425_S	571_P	1.867	1.00
513_L	519_V	1.865	1.00
598_R	601_A	1.861	1.00
266_S	280_V	1.856	1.00
468_I	485_I	1.853	1.00
268_V	324_M	1.844	1.00
416_L	440_L	1.836	1.00
416_L	464_I	1.807	1.00
18_P	95_H	1.799	1.00
243_A	248_A	1.794	1.00
531_L	557_K	1.757	1.00
189_K	225_E	1.754	1.00
540_T	543_E	1.750	1.00
291_M	358_L	1.748	1.00
84_V	93_R	1.742	1.00
343_A	347_S	1.740	1.00
8_D	80_P	1.738	1.00
242_F	349_V	1.735	1.00
58_I	68_I	1.733	1.00
266_S	273_T	1.730	1.00
56_D	203_K	1.728	1.00
136_V	156_C	1.720	1.00
54_R	201_T	1.709	1.00
58_I	205_E	1.697	1.00
91_L	116_I	1.695	1.00
37_Q	184_L	1.655	1.00
77_D	133_D	1.652	1.00
131_R	164_S	1.641	1.00
357_W	361_N	1.640	1.00
503_C	519_V	1.634	1.00
140_A	148_Q	1.631	1.00
136_V	154_G	1.625	1.00
220_N	224_A	1.623	1.00
14_T	82_E	1.611	1.00
468_I	480_L	1.580	1.00
65_L	179_F	1.572	1.00
201_T	212_R	1.562	1.00
185_T	211_Q	1.555	1.00
58_I	203_K	1.553	1.00
476_D	479_Q	1.552	1.00
138_N	153_V	1.538	0.99
283_L	318_Y	1.538	0.99
6_N	9_A	1.532	0.99
529_I	547_V	1.525	0.99
247_E	345_F	1.521	0.99
521_V	589_L	1.518	0.99
227_V	254_L	1.516	0.99
193_V	225_E	1.511	0.99
294_F	365_A	1.506	0.99
361_N	364_A	1.473	0.99
77_D	86_A	1.464	0.99
611_R	614_D	1.463	0.99
40_I	67_V	1.459	0.99
91_L	126_V	1.459	0.99
309_A	313_W	1.450	0.99
116_I	126_V	1.448	0.99
181_V	213_W	1.435	0.99
231_P	257_P	1.433	0.99
406_A	412_T	1.433	0.99
283_L	320_L	1.424	0.99
253_L	316_C	1.420	0.99
354_F	358_L	1.414	0.99
125_R	142_E	1.407	0.99
512_A	516_H	1.405	0.99
295_C	301_L	1.405	0.99
410_N	483_G	1.404	0.99
141_F	146_K	1.404	0.99
64_S	168_W	1.402	0.99
536_Y	550_Q	1.401	0.99
89_L	93_R	1.392	0.99
543_E	546_G	1.388	0.99
11_E	101_S	1.388	0.99
342_C	345_F	1.382	0.99
544_K	548_L	1.379	0.99
441_K	460_E	1.378	0.99
77_D	132_R	1.374	0.99
412_T	483_G	1.361	0.99
241_N	250_D	1.342	0.99
243_A	246_T	1.338	0.99
453_D	457_A	1.335	0.99
68_I	160_N	1.332	0.99
146_K	149_D	1.321	0.98
227_V	317_A	1.302	0.98
268_V	273_T	1.297	0.98
44_V	191_K	1.289	0.98
314_D	375_S	1.287	0.98
157_G	160_N	1.284	0.98
459_Q	463_D	1.280	0.98
414_L	464_I	1.277	0.98
536_Y	547_V	1.277	0.98
561_Q	573_Q	1.275	0.98
126_V	165_V	1.272	0.98
58_I	66_E	1.270	0.98
236_K	364_A	1.267	0.98
97_G	100_F	1.262	0.98
296_E	304_G	1.258	0.98
444_I	461_V	1.254	0.98
78_I	83_G	1.252	0.98
11_E	21_R	1.246	0.98
63_Q	178_R	1.241	0.98
502_L	506_F	1.241	0.98
131_R	161_T	1.236	0.98
528_R	535_V	1.232	0.98
460_E	463_D	1.220	0.97
485_I	506_F	1.215	0.97
409_L	412_T	1.212	0.97
91_L	128_V	1.211	0.97
220_N	239_I	1.203	0.97
546_G	550_Q	1.200	0.97
477_L	516_H	1.199	0.97
109_G	271_I	1.198	0.97
594_E	599_T	1.197	0.97
470_I	475_D	1.195	0.97
274_M	335_E	1.193	0.97
47_A	198_V	1.189	0.97
219_L	239_I	1.187	0.97
168_W	171_E	1.185	0.97
411_R	433_E	1.184	0.97
324_M	342_C	1.182	0.97
295_C	369_A	1.181	0.97
180_S	183_R	1.181	0.97
441_K	444_I	1.180	0.97
331_G	338_S	1.180	0.97
59_L	63_Q	1.174	0.97
529_I	544_K	1.173	0.97
64_S	169_P	1.171	0.97
238_F	253_L	1.171	0.97
52_A	55_V	1.168	0.97
529_I	538_A	1.165	0.97
616_R	620_Q	1.164	0.97
275_Q	331_G	1.160	0.96
291_M	312_I	1.157	0.96
43_S	165_V	1.157	0.96
263_L	284_R	1.155	0.96
36_G	40_I	1.150	0.96
201_T	210_E	1.147	0.96
64_S	166_H	1.145	0.96
21_R	326_D	1.143	0.96
140_A	151_Q	1.142	0.96
353_A	356_L	1.142	0.96
428_Q	571_P	1.140	0.96
575_R	581_P	1.133	0.96
51_H	72_R	1.132	0.96
185_T	213_W	1.131	0.96
139_I	148_Q	1.131	0.96
411_R	434_Y	1.130	0.96
240_G	251_W	1.129	0.96
247_E	342_C	1.126	0.96
141_F	148_Q	1.124	0.96
535_V	538_A	1.118	0.96
536_Y	543_E	1.117	0.96
4_T	9_A	1.116	0.96
444_I	489_A	1.114	0.96
389_K	403_D	1.113	0.95
63_Q	168_W	1.108	0.95
545_E	549_E	1.108	0.95
544_K	558_P	1.101	0.95
452_S	456_L	1.100	0.95
416_L	460_E	1.100	0.95
60_H	63_Q	1.099	0.95
331_G	335_E	1.094	0.95
141_F	150_L	1.094	0.95
136_V	153_V	1.093	0.95
413_E	486_C	1.093	0.95
40_I	188_L	1.090	0.95
506_F	519_V	1.088	0.95
538_A	544_K	1.085	0.95
64_S	125_R	1.085	0.95
181_V	185_T	1.081	0.95
548_L	560_V	1.081	0.95
470_I	477_L	1.079	0.95
288_L	309_A	1.078	0.95
10_I	86_A	1.076	0.95
249_V	349_V	1.075	0.95
350_V	354_F	1.074	0.95
358_L	365_A	1.073	0.94
248_A	323_K	1.072	0.94
499_A	521_V	1.070	0.94
322_V	342_C	1.068	0.94
196_P	250_D	1.067	0.94
285_Q	347_S	1.066	0.94
470_I	480_L	1.065	0.94
135_Q	154_G	1.064	0.94
330_A	338_S	1.064	0.94
367_L	370_E	1.062	0.94
356_L	360_Q	1.061	0.94
538_A	543_E	1.059	0.94
405_T	433_E	1.053	0.94
133_D	137_Y	1.052	0.94
531_L	552_K	1.052	0.94
171_E	177_P	1.051	0.94
330_A	335_E	1.041	0.94
19_V	94_L	1.041	0.94
293_E	296_E	1.040	0.94
576_E	580_D	1.038	0.93
130_V	150_L	1.028	0.93
78_I	81_E	1.027	0.93
434_Y	581_P	1.021	0.93
604_D	611_R	1.015	0.93
286_G	290_A	1.014	0.93
480_L	516_H	1.012	0.93
132_R	161_T	1.010	0.92
268_V	322_V	1.006	0.92
189_K	215_Y	1.001	0.92
328_Q	338_S	1.001	0.92
487_I	506_F	1.001	0.92
79_H	86_A	1.001	0.92
441_K	459_Q	1.000	0.92
43_S	91_L	0.999	0.92
601_A	605_M	0.998	0.92
131_R	156_C	0.995	0.92
259_G	388_R	0.993	0.92
228_N	601_A	0.992	0.92
431_D	434_Y	0.991	0.92
273_T	338_S	0.987	0.92
225_E	601_A	0.986	0.92
68_I	131_R	0.982	0.91
143_N	170_D	0.980	0.91
255_W	312_I	0.979	0.91
371_M	388_R	0.976	0.91
217_D	220_N	0.973	0.91
311_D	379_R	0.973	0.91
193_V	215_Y	0.971	0.91
217_D	221_D	0.970	0.91
78_I	82_E	0.970	0.91
402_A	432_R	0.969	0.91
444_I	463_D	0.968	0.91
613_E	617_N	0.968	0.91
281_N	285_Q	0.964	0.91
444_I	460_E	0.962	0.91
273_T	331_G	0.960	0.90
136_V	160_N	0.959	0.90
249_V	345_F	0.955	0.90
130_V	163_T	0.953	0.90
47_A	52_A	0.953	0.90
545_E	548_L	0.950	0.90
35_L	119_V	0.950	0.90
347_S	351_K	0.948	0.90
296_E	301_L	0.945	0.90
74_M	165_V	0.944	0.90
74_M	91_L	0.944	0.90
344_A	348_G	0.939	0.89
398_P	403_D	0.932	0.89
462_H	466_V	0.927	0.89
80_P	83_G	0.925	0.89
85_P	89_L	0.924	0.89
444_I	458_S	0.918	0.88
412_T	518_H	0.917	0.88
124_K	172_T	0.915	0.88
79_H	84_V	0.915	0.88
76_V	132_R	0.913	0.88
39_V	91_L	0.911	0.88
116_I	128_V	0.910	0.88
575_R	580_D	0.908	0.88
563_F	573_Q	0.905	0.88
84_V	89_L	0.905	0.88
188_L	202_F	0.904	0.88
448_W	508_K	0.903	0.88
136_V	152_V	0.902	0.88
236_K	361_N	0.901	0.87
220_N	236_K	0.901	0.87
185_T	202_F	0.900	0.87
85_P	150_L	0.897	0.87
593_D	598_R	0.895	0.87
247_E	324_M	0.894	0.87
263_L	318_Y	0.893	0.87
217_D	224_A	0.886	0.87
281_N	347_S	0.885	0.87
295_C	307_L	0.884	0.86
234_P	364_A	0.882	0.86
48_L	52_A	0.881	0.86
268_V	338_S	0.880	0.86
465_S	505_L	0.877	0.86
102_N	326_D	0.877	0.86
4_T	7_A	0.877	0.86
460_E	489_A	0.876	0.86
352_D	356_L	0.875	0.86
464_I	489_A	0.871	0.86
78_I	84_V	0.871	0.86
299_N	303_R	0.870	0.86
301_L	306_K	0.869	0.85
191_K	195_C	0.867	0.85
6_N	77_D	0.864	0.85
11_E	81_E	0.859	0.85
531_L	556_G	0.859	0.85
301_L	304_G	0.857	0.85
156_C	161_T	0.849	0.84
458_S	463_D	0.849	0.84
54_R	212_R	0.848	0.84
139_I	150_L	0.848	0.84
366_E	370_E	0.847	0.84
389_K	393_S	0.847	0.84
116_I	165_V	0.845	0.84
203_K	208_N	0.845	0.84
572_M	580_D	0.843	0.84
86_A	89_L	0.843	0.84
9_A	104_N	0.842	0.84
13_L	21_R	0.839	0.83
48_L	202_F	0.837	0.83
289_D	347_S	0.834	0.83
415_F	434_Y	0.833	0.83
312_I	372_A	0.831	0.83
456_L	461_V	0.831	0.83
266_S	331_G	0.830	0.83
18_P	24_G	0.828	0.83
552_K	557_K	0.828	0.83
528_R	573_Q	0.827	0.83
403_D	481_R	0.823	0.82
617_N	620_Q	0.823	0.82
602_M	605_M	0.823	0.82
339_S	342_C	0.821	0.82
428_Q	570_N	0.820	0.82
57_V	202_F	0.817	0.82
184_L	188_L	0.817	0.82
478_S	516_H	0.816	0.82
292_R	296_E	0.814	0.82
143_N	173_F	0.813	0.81
70_D	160_N	0.812	0.81
263_L	280_V	0.811	0.81
53_K	199_E	0.811	0.81
275_Q	336_R	0.811	0.81
241_N	248_A	0.811	0.81
12_V	82_E	0.810	0.81
268_V	329_F	0.810	0.81
273_T	330_A	0.810	0.81
15_G	19_V	0.807	0.81
79_H	89_L	0.804	0.81
138_N	148_Q	0.803	0.81
499_A	523_L	0.803	0.81
51_H	145_E	0.800	0.80
427_K	573_Q	0.800	0.80
600_D	604_D	0.799	0.80
189_K	193_V	0.796	0.80
553_R	557_K	0.790	0.80
16_L	94_L	0.790	0.80
315_R	371_M	0.790	0.80
249_V	346_V	0.787	0.79
541_E	545_E	0.787	0.79
237_P	252_A	0.786	0.79
351_K	355_I	0.786	0.79
170_D	173_F	0.786	0.79
365_A	369_A	0.786	0.79
447_T	455_V	0.786	0.79
266_S	338_S	0.786	0.79
614_D	617_N	0.785	0.79
531_L	551_L	0.784	0.79
249_V	252_A	0.784	0.79
124_K	170_D	0.776	0.78
59_L	206_I	0.775	0.78
84_V	146_K	0.773	0.78
88_E	139_I	0.772	0.78
464_I	505_L	0.770	0.78
488_L	522_A	0.770	0.78
11_E	14_T	0.769	0.78
290_A	355_I	0.767	0.78
53_K	57_V	0.767	0.78
224_A	237_P	0.767	0.78
18_P	94_L	0.766	0.77
234_P	254_L	0.764	0.77
18_P	21_R	0.763	0.77
357_W	364_A	0.763	0.77
76_V	87_V	0.762	0.77
224_A	236_K	0.762	0.77
134_G	157_G	0.758	0.77
378_R	383_A	0.757	0.77
63_Q	179_F	0.756	0.77
133_D	152_V	0.754	0.76
374_S	377_Q	0.752	0.76
167_F	179_F	0.752	0.76
281_N	343_A	0.751	0.76
426_A	437_I	0.751	0.76
488_L	579_L	0.749	0.76
77_D	137_Y	0.748	0.76
399_G	467_A	0.747	0.76
62_D	166_H	0.747	0.76
509_H	539_L	0.747	0.76
185_T	209_T	0.747	0.76
590_T	594_E	0.746	0.76
12_V	89_L	0.746	0.76
242_F	353_A	0.746	0.76
14_T	18_P	0.746	0.76
126_V	139_I	0.745	0.75
124_K	143_N	0.744	0.75
535_V	576_E	0.743	0.75
514_V	519_V	0.740	0.75
573_Q	576_E	0.739	0.75
251_W	283_L	0.739	0.75
153_V	156_C	0.738	0.75
409_L	518_H	0.735	0.75
378_R	387_V	0.735	0.75
470_I	510_F	0.734	0.74
80_P	86_A	0.733	0.74
234_P	237_P	0.732	0.74
547_V	550_Q	0.731	0.74
406_A	433_E	0.731	0.74
181_V	209_T	0.730	0.74
363_Q	367_L	0.728	0.74
415_F	575_R	0.728	0.74
223_L	319_V	0.727	0.74
37_Q	183_R	0.727	0.74
374_S	388_R	0.726	0.74
285_Q	343_A	0.726	0.74
273_T	328_Q	0.725	0.73
266_S	328_Q	0.725	0.73
328_Q	339_S	0.724	0.73
16_L	95_H	0.723	0.73
459_Q	462_H	0.723	0.73
249_V	258_E	0.722	0.73
259_G	371_M	0.721	0.73
7_A	133_D	0.720	0.73
404_C	481_R	0.720	0.73
44_V	200_I	0.719	0.73
135_Q	153_V	0.719	0.73
370_E	374_S	0.718	0.73
14_T	145_E	0.718	0.73
398_P	481_R	0.716	0.73
463_D	466_V	0.715	0.72
387_V	390_K	0.713	0.72
283_L	350_V	0.712	0.72
468_I	483_G	0.712	0.72
266_S	320_L	0.711	0.72
275_Q	340_R	0.710	0.72
90_I	165_V	0.708	0.72
136_V	155_T	0.705	0.71
530_D	559_N	0.704	0.71
82_E	93_R	0.700	0.71
542_E	545_E	0.699	0.71
171_E	178_R	0.699	0.71
618_W	623_G	0.698	0.71
5_Y	10_I	0.697	0.71
397_L	432_R	0.697	0.71
431_D	581_P	0.696	0.70
363_Q	366_E	0.692	0.70
190_A	222_Y	0.692	0.70
415_F	484_K	0.692	0.70
618_W	622_K	0.691	0.70
16_L	19_V	0.691	0.70
412_T	480_L	0.690	0.70
587_V	626_A	0.690	0.70
447_T	461_V	0.690	0.70
290_A	354_F	0.690	0.70
441_K	461_V	0.688	0.70
275_Q	330_A	0.687	0.69
289_D	351_K	0.686	0.69
500_T	603_M	0.685	0.69
272_P	280_V	0.685	0.69
125_R	147_V	0.683	0.69
280_V	290_A	0.683	0.69
170_D	273_T	0.681	0.69
96_A	117_S	0.681	0.69
81_E	145_E	0.681	0.69
496_L	573_Q	0.681	0.69
386_V	389_K	0.680	0.69
57_V	207_N	0.678	0.68
485_I	519_V	0.677	0.68
137_Y	161_T	0.676	0.68
27_T	30_T	0.676	0.68
477_L	480_L	0.675	0.68
415_F	586_L	0.674	0.68
335_E	339_S	0.674	0.68
410_N	518_H	0.673	0.68
93_R	141_F	0.673	0.68
96_A	100_F	0.673	0.68
373_I	377_Q	0.672	0.68
314_D	371_M	0.671	0.68
191_K	270_L	0.668	0.67
82_E	85_P	0.666	0.67
284_R	313_W	0.664	0.67
259_G	387_V	0.664	0.67
89_L	222_Y	0.663	0.67
593_D	597_Q	0.663	0.67
9_A	103_K	0.662	0.67
125_R	166_H	0.662	0.67
62_D	168_W	0.661	0.66
85_P	146_K	0.660	0.66
127_E	142_E	0.660	0.66
512_A	591_I	0.660	0.66
197_G	214_C	0.659	0.66
598_R	602_M	0.659	0.66
265_E	597_Q	0.659	0.66
244_G	345_F	0.657	0.66
437_I	579_L	0.656	0.66
389_K	412_T	0.656	0.66
468_I	519_V	0.655	0.66
515_K	594_E	0.655	0.66
251_W	257_P	0.655	0.66
380_M	383_A	0.655	0.66
136_V	141_F	0.655	0.66
100_F	112_H	0.654	0.66
56_D	66_E	0.654	0.66
507_V	599_T	0.652	0.65
537_Y	573_Q	0.651	0.65
414_L	485_I	0.651	0.65
404_C	618_W	0.650	0.65
395_P	454_E	0.650	0.65
19_V	117_S	0.649	0.65
27_T	31_R	0.649	0.65
234_P	255_W	0.648	0.65
22_R	111_L	0.648	0.65
543_E	585_R	0.648	0.65
465_S	472_P	0.647	0.65
577_T	584_R	0.646	0.65
57_V	200_I	0.646	0.65
124_K	140_A	0.645	0.65
248_A	251_W	0.645	0.65
394_G	466_V	0.645	0.65
58_I	64_S	0.644	0.64
399_G	432_R	0.644	0.64
529_I	548_L	0.643	0.64
250_D	257_P	0.643	0.64
196_P	239_I	0.643	0.64
76_V	135_Q	0.643	0.64
54_R	68_I	0.641	0.64
405_T	412_T	0.641	0.64
542_E	546_G	0.640	0.64
35_L	273_T	0.640	0.64
268_V	331_G	0.639	0.64
86_A	104_N	0.639	0.64
91_L	139_I	0.638	0.64
21_R	135_Q	0.638	0.64
327_P	447_T	0.638	0.64
160_N	164_S	0.638	0.64
312_I	457_A	0.637	0.64
278_T	340_R	0.636	0.64
452_S	455_V	0.635	0.63
539_L	547_V	0.635	0.63
187_V	191_K	0.635	0.63
563_F	576_E	0.633	0.63
229_G	604_D	0.633	0.63
251_W	350_V	0.631	0.63
9_A	101_S	0.631	0.63
78_I	85_P	0.630	0.63
140_A	168_W	0.630	0.63
406_A	409_L	0.630	0.63
138_N	154_G	0.630	0.63
561_Q	575_R	0.630	0.63
552_K	558_P	0.628	0.63
240_G	464_I	0.627	0.62
505_L	510_F	0.627	0.62
11_E	102_N	0.626	0.62
227_V	256_L	0.625	0.62
83_G	145_E	0.625	0.62
91_L	163_T	0.625	0.62
39_V	118_V	0.624	0.62
441_K	489_A	0.624	0.62
251_W	259_G	0.622	0.62
441_K	464_I	0.622	0.62
221_D	463_D	0.621	0.62
295_C	299_N	0.621	0.62
381_R	385_K	0.620	0.62
549_E	553_R	0.619	0.61
232_T	254_L	0.618	0.61
9_A	102_N	0.617	0.61
256_L	259_G	0.616	0.61
523_L	585_R	0.616	0.61
63_Q	177_P	0.616	0.61
609_K	614_D	0.615	0.61
90_I	272_P	0.614	0.61
137_Y	141_F	0.614	0.61
551_L	558_P	0.613	0.61
220_N	237_P	0.613	0.61
293_E	351_K	0.612	0.61
43_S	55_V	0.612	0.61
445_L	455_V	0.612	0.61
414_L	480_L	0.612	0.61
54_R	203_K	0.611	0.60
168_W	179_F	0.611	0.60
91_L	146_K	0.611	0.60
12_V	18_P	0.610	0.60
85_P	149_D	0.610	0.60
597_Q	601_A	0.609	0.60
594_E	597_Q	0.609	0.60
373_I	381_R	0.607	0.60
544_K	560_V	0.607	0.60
608_A	612_S	0.607	0.60
445_L	450_V	0.607	0.60
4_T	8_D	0.606	0.60
465_S	471_D	0.604	0.60
65_L	202_F	0.603	0.59
87_V	126_V	0.603	0.59
68_I	129_N	0.602	0.59
471_D	475_D	0.602	0.59
105_Y	325_Q	0.601	0.59
87_V	139_I	0.600	0.59
455_V	461_V	0.600	0.59
46_E	50_G	0.600	0.59
216_Q	236_K	0.599	0.59
403_D	408_D	0.599	0.59
412_T	433_E	0.599	0.59
480_L	513_L	0.599	0.59
504_A	607_L	0.598	0.59
237_P	240_G	0.598	0.59
250_D	258_E	0.598	0.59
253_L	287_L	0.597	0.59
548_L	551_L	0.597	0.59
40_I	57_V	0.596	0.59
74_M	87_V	0.595	0.58
514_V	591_I	0.595	0.58
613_E	616_R	0.594	0.58
411_R	483_G	0.594	0.58
275_Q	339_S	0.594	0.58
523_L	626_A	0.593	0.58
300_I	373_I	0.592	0.58
427_K	432_R	0.592	0.58
252_A	258_E	0.591	0.58
79_H	82_E	0.591	0.58
61_A	208_N	0.590	0.58
426_A	488_L	0.590	0.58
78_I	87_V	0.590	0.58
84_V	149_D	0.589	0.58
139_I	149_D	0.589	0.58
445_L	458_S	0.588	0.58
429_A	575_R	0.588	0.58
413_E	484_K	0.587	0.57
29_T	338_S	0.585	0.57
66_E	125_R	0.585	0.57
407_Q	546_G	0.584	0.57
391_L	396_A	0.584	0.57
550_Q	556_G	0.583	0.57
496_L	499_A	0.583	0.57
129_N	153_V	0.581	0.57
209_T	621_E	0.581	0.57
129_N	202_F	0.581	0.57
508_K	600_D	0.580	0.56
247_E	325_Q	0.580	0.56
240_G	350_V	0.580	0.56
389_K	392_T	0.578	0.56
142_E	145_E	0.577	0.56
322_V	346_V	0.577	0.56
237_P	364_A	0.576	0.56
286_G	354_F	0.576	0.56
60_H	203_K	0.575	0.56
67_V	165_V	0.575	0.56
284_R	309_A	0.574	0.56
327_P	481_R	0.574	0.56
569_M	574_L	0.574	0.56
268_V	325_Q	0.573	0.56
272_P	335_E	0.573	0.56
461_V	505_L	0.573	0.56
489_A	499_A	0.572	0.55
296_E	539_L	0.572	0.55
529_I	551_L	0.571	0.55
42_N	45_D	0.571	0.55
398_P	467_A	0.570	0.55
441_K	456_L	0.569	0.55
240_G	244_G	0.569	0.55
15_G	95_H	0.568	0.55
503_C	603_M	0.568	0.55
231_P	611_R	0.567	0.55
441_K	463_D	0.567	0.55
246_T	325_Q	0.567	0.55
402_A	437_I	0.567	0.55
440_L	502_L	0.567	0.55
590_T	602_M	0.565	0.55
24_G	102_N	0.565	0.55
249_V	256_L	0.565	0.55
191_K	327_P	0.565	0.55
539_L	585_R	0.565	0.55
550_Q	553_R	0.565	0.55
406_A	410_N	0.564	0.54
299_N	369_A	0.562	0.54
594_E	602_M	0.561	0.54
291_M	369_A	0.561	0.54
142_E	148_Q	0.561	0.54
195_C	270_L	0.561	0.54
149_D	152_V	0.561	0.54
280_V	394_G	0.561	0.54
43_S	163_T	0.559	0.54
552_K	556_G	0.559	0.54
608_A	619_L	0.557	0.54
244_G	247_E	0.557	0.54
132_R	249_V	0.556	0.53
98_G	108_S	0.554	0.53
145_E	236_K	0.554	0.53
548_L	552_K	0.553	0.53
199_E	216_Q	0.553	0.53
280_V	284_R	0.553	0.53
244_G	348_G	0.552	0.53
59_L	202_F	0.552	0.53
562_R	568_E	0.551	0.53
412_T	481_R	0.551	0.53
87_V	273_T	0.550	0.53
38_E	42_N	0.550	0.53
478_S	483_G	0.550	0.53
92_C	146_K	0.550	0.53
127_E	147_V	0.549	0.52
548_L	558_P	0.549	0.52
536_Y	551_L	0.548	0.52
12_V	189_K	0.548	0.52
448_W	604_D	0.547	0.52
515_K	591_I	0.547	0.52
511_R	616_R	0.546	0.52
63_Q	169_P	0.546	0.52
598_R	621_E	0.545	0.52
373_I	376_A	0.545	0.52
489_A	496_L	0.545	0.52
395_P	459_Q	0.544	0.52
44_V	195_C	0.544	0.52
377_Q	451_S	0.544	0.52
157_G	236_K	0.544	0.52
185_T	267_Y	0.543	0.52
44_V	344_A	0.541	0.51
261_E	313_W	0.541	0.51
585_R	602_M	0.541	0.51
76_V	79_H	0.541	0.51
398_P	463_D	0.540	0.51
591_I	609_K	0.540	0.51
546_G	549_E	0.540	0.51
394_G	462_H	0.539	0.51
330_A	336_R	0.539	0.51
148_Q	152_V	0.539	0.51
455_V	489_A	0.539	0.51
251_W	260_G	0.539	0.51
428_Q	432_R	0.539	0.51
66_E	205_E	0.538	0.51
178_R	202_F	0.538	0.51
240_G	353_A	0.538	0.51
300_I	369_A	0.537	0.51
370_E	617_N	0.537	0.51
414_L	470_I	0.537	0.51
101_S	296_E	0.537	0.51
106_Q	270_L	0.536	0.51
47_A	50_G	0.536	0.51
24_G	487_I	0.534	0.51
384_K	465_S	0.534	0.51
363_Q	381_R	0.534	0.51
157_G	560_V	0.534	0.51
309_A	315_R	0.533	0.50
430_R	435_Q	0.533	0.50
444_I	459_Q	0.533	0.50
403_D	434_Y	0.533	0.50
63_Q	125_R	0.533	0.50
103_K	106_Q	0.532	0.50
335_E	338_S	0.532	0.50
291_M	354_F	0.532	0.50
90_I	335_E	0.531	0.50
77_D	80_P	0.531	0.50
330_A	339_S	0.530	0.50
8_D	79_H	0.530	0.50
288_L	292_R	0.530	0.50
415_F	499_A	0.529	0.50
259_G	381_R	0.529	0.50
171_E	175_D	0.529	0.50
16_L	121_A	0.528	0.50
362_V	365_A	0.528	0.50
408_D	412_T	0.528	0.50
452_S	472_P	0.528	0.50
328_Q	331_G	0.527	0.50
36_G	59_L	0.527	0.50
579_L	620_Q	0.527	0.50
12_V	93_R	0.527	0.50
454_E	618_W	0.527	0.50
484_K	586_L	0.527	0.50
184_L	200_I	0.526	0.49
307_L	373_I	0.526	0.49
407_Q	483_G	0.526	0.49
3_Q	6_N	0.526	0.49
293_E	355_I	0.525	0.49
79_H	428_Q	0.525	0.49
572_M	576_E	0.525	0.49
88_E	141_F	0.525	0.49
275_Q	338_S	0.524	0.49
424_G	430_R	0.524	0.49
391_L	412_T	0.524	0.49
300_I	304_G	0.524	0.49
230_L	604_D	0.524	0.49
570_N	573_Q	0.524	0.49
364_A	367_L	0.523	0.49
527_Y	561_Q	0.521	0.49
52_A	71_G	0.521	0.49
252_A	257_P	0.521	0.49
403_D	493_S	0.520	0.49
575_R	582_N	0.520	0.49
233_L	364_A	0.520	0.49
426_A	574_L	0.520	0.49
15_G	21_R	0.519	0.49
605_M	611_R	0.518	0.48
242_F	256_L	0.518	0.48
229_G	232_T	0.518	0.48
369_A	372_A	0.518	0.48
13_L	19_V	0.518	0.48
226_A	317_A	0.517	0.48
574_L	577_T	0.515	0.48
327_P	412_T	0.515	0.48
12_V	15_G	0.514	0.48
539_L	543_E	0.514	0.48
136_V	157_G	0.514	0.48
145_E	151_Q	0.514	0.48
130_V	165_V	0.514	0.48
396_A	466_V	0.514	0.48
414_L	519_V	0.513	0.48
15_G	18_P	0.513	0.48
185_T	222_Y	0.513	0.48
544_K	557_K	0.512	0.48
191_K	335_E	0.512	0.48
77_D	89_L	0.511	0.47
191_K	499_A	0.511	0.47
295_C	306_K	0.511	0.47
227_V	234_P	0.511	0.47
484_K	520_Y	0.511	0.47
8_D	77_D	0.511	0.47
288_L	313_W	0.511	0.47
416_L	420_D	0.510	0.47
415_F	581_P	0.509	0.47
102_N	268_V	0.509	0.47
549_E	552_K	0.508	0.47
267_Y	302_P	0.507	0.47
13_L	24_G	0.507	0.47
3_Q	210_E	0.506	0.47
463_D	489_A	0.506	0.47
392_T	499_A	0.506	0.47
181_V	206_I	0.506	0.47
3_Q	207_N	0.505	0.47
291_M	368_L	0.505	0.47
145_E	170_D	0.505	0.47
326_D	339_S	0.505	0.47
175_D	340_R	0.505	0.47
539_L	544_K	0.505	0.47
325_Q	345_F	0.504	0.47
268_V	328_Q	0.503	0.46
38_E	45_D	0.503	0.46
55_V	312_I	0.503	0.46
19_V	23_P	0.503	0.46
190_A	272_P	0.503	0.46
450_V	455_V	0.502	0.46
221_D	303_R	0.502	0.46
16_L	21_R	0.501	0.46
14_T	93_R	0.500	0.46
144_G	173_F	0.500	0.46
222_Y	441_K	0.500	0.46

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4i3hA	2	0.8857	100	0.092	Contact Map
4gfhA	2	0.919	100	0.152	Contact Map
3zkbA	5	0.6016	100	0.543	Contact Map
3lnuA	1	0.5444	100	0.548	Contact Map
1s16A	2	0.6032	100	0.557	Contact Map
1zxmA	2	0.5508	100	0.559	Contact Map
4wubA	2	0.5984	100	0.564	Contact Map
1pvgA	2	0.5492	100	0.568	Contact Map
4urlA	1	0.5635	100	0.569	Contact Map
2xkjE	2	0.3762	100	0.571	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0161 seconds.