PTOCB - ECOLI - GREMLIN Contacts

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PTOCB - PTS system maltose- and glucose-specific EIICB component

UniProt:	P19642	Sequences: MTAKTAPKVTLWEFFQQLGKTFMLPVALLSFCGIMLGIGSSLSSHDVITLIPVLGNPVLQAIFTWMSKIGSFAFSFLPVMFCIAIPLGLARENKGVAAFAGFIGYAVMNLAVNFWLTNKGILPTTDAAVLKANNIQSILGIQSIDTGILGAVIAGIIVWMLHERFHNIRLPDALAFFGGTRFVPIISSLVMGLVGLVIPLVWPIFAMGISGLGHMINSAGDFGPMLFGTGERLLLPFGLHHILVALIRFTDAGGTQEVCGQTVSGALTIFQAQLSCPTTHGFSESATRFLSQGKMPAFLGGLPGAALAMYHCARPENRHKIKGLLISGLIACVVGGTTEPLEFLFLFVAPVLYVIHALLTGLGFTVMSVLGVTIGNTDGNIIDFVVFGILHGLSTKWYMVPVVAAIWFVVYYVIFRFAITRFNLKTPGRDSEVASSIEKAVAGAPGKSGYNVPAILEALGGADNIVSLDNCITRLRLSVKDMSLVNVQALKDNRAIGVVQLNQHNLQVVIGPQVQSVKDEMAGLMHTVQA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10563
Length:	530 (486)
Sequences:	2312 (1239)
Seq/√Len:	56.2

ECOLI - PTOCB PTW3C PTGCB PTXC PTIBC
BACSU - PTG3C PTW3C PTOCB PTWCB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
304_G	408_F	5.324	1.00
311_H	416_R	5.119	1.00
487_V	500_Q	4.853	1.00
311_H	412_Y	4.825	1.00
416_R	420_T	4.536	1.00
83_I	102_F	3.856	1.00
425_K	431_S	3.802	1.00
466_V	480_K	3.726	1.00
71_S	75_S	3.630	1.00
401_P	405_A	3.525	1.00
104_G	187_S	3.411	1.00
317_N	320_K	3.267	1.00
33_G	376_N	3.208	1.00
317_N	432_E	3.200	1.00
314_R	431_S	3.187	1.00
359_L	414_I	3.104	1.00
405_A	409_V	3.050	1.00
306_A	341_L	3.041	1.00
468_L	525_M	3.032	1.00
312_C	420_T	3.018	1.00
309_M	325_L	2.868	1.00
300_G	404_A	2.776	1.00
354_V	358_L	2.774	1.00
312_C	416_R	2.724	1.00
470_N	514_V	2.674	1.00
481_D	484_L	2.631	1.00
418_A	422_F	2.572	1.00
370_L	403_V	2.555	1.00
486_N	489_A	2.523	1.00
168_I	182_F	2.504	1.00
231_E	294_K	2.485	1.00
459_L	508_V	2.452	1.00
449_G	520_E	2.406	1.00
299_L	333_V	2.395	1.00
228_G	364_F	2.293	1.00
157_I	194_V	2.275	1.00
355_I	359_L	2.269	1.00
356_H	411_Y	2.264	1.00
456_L	525_M	2.149	1.00
355_I	418_A	2.116	1.00
410_V	414_I	2.108	1.00
489_A	492_D	2.098	1.00
158_V	187_S	2.095	1.00
468_L	521_M	2.044	1.00
367_M	403_V	2.029	1.00
21_T	89_L	2.025	1.00
355_I	414_I	2.010	1.00
371_G	396_K	1.986	1.00
365_T	369_V	1.960	1.00
458_A	489_A	1.960	1.00
456_L	524_L	1.956	1.00
351_V	422_F	1.917	1.00
381_I	385_V	1.897	1.00
287_T	290_L	1.892	1.00
456_L	521_M	1.870	1.00
322_K	326_I	1.851	0.99
499_V	509_V	1.845	0.99
156_I	160_M	1.840	0.99
229_T	354_V	1.834	0.99
510_I	514_V	1.834	0.99
417_F	421_R	1.831	0.99
479_V	482_M	1.825	0.99
302_L	305_A	1.823	0.99
40_S	67_S	1.801	0.99
455_I	510_I	1.784	0.99
409_V	413_V	1.765	0.99
189_L	193_L	1.763	0.99
414_I	418_A	1.747	0.99
168_I	178_G	1.746	0.99
79_V	102_F	1.740	0.99
307_L	311_H	1.737	0.99
451_N	513_Q	1.737	0.99
229_T	357_A	1.691	0.99
467_S	478_S	1.676	0.99
154_A	194_V	1.666	0.99
23_M	241_H	1.662	0.99
154_A	191_M	1.662	0.99
311_H	420_T	1.659	0.99
157_I	190_V	1.657	0.99
20_K	469_D	1.646	0.99
310_Y	322_K	1.637	0.99
196_L	200_L	1.606	0.98
402_V	406_I	1.604	0.98
15_F	18_L	1.599	0.98
186_I	190_V	1.598	0.98
230_G	243_L	1.595	0.98
435_S	438_E	1.591	0.98
138_I	141_I	1.584	0.98
398_Y	402_V	1.584	0.98
265_G	269_I	1.576	0.98
405_A	408_F	1.575	0.98
456_L	468_L	1.574	0.98
296_P	363_G	1.568	0.98
39_G	70_G	1.560	0.98
297_A	360_T	1.557	0.98
477_L	521_M	1.555	0.98
227_F	292_Q	1.536	0.98
233_L	357_A	1.535	0.98
482_M	506_L	1.525	0.98
169_R	172_D	1.516	0.98
490_L	508_V	1.510	0.98
222_F	226_L	1.507	0.98
285_S	290_L	1.496	0.98
77_L	148_I	1.491	0.98
495_A	498_V	1.490	0.98
479_V	485_V	1.489	0.98
426_T	429_R	1.476	0.97
161_L	182_F	1.466	0.97
256_Q	262_T	1.463	0.97
466_V	504_H	1.458	0.97
161_L	190_V	1.458	0.97
286_A	289_F	1.458	0.97
314_R	430_D	1.453	0.97
487_V	491_K	1.452	0.97
466_V	478_S	1.448	0.97
457_E	489_A	1.443	0.97
31_F	188_S	1.442	0.97
419_I	426_T	1.435	0.97
315_P	318_R	1.425	0.97
367_M	372_V	1.420	0.97
257_E	261_Q	1.416	0.97
385_V	389_I	1.412	0.97
319_H	322_K	1.407	0.96
459_L	477_L	1.403	0.96
269_I	273_Q	1.396	0.96
425_K	430_D	1.384	0.96
399_M	402_V	1.379	0.96
470_N	493_N	1.379	0.96
310_Y	318_R	1.376	0.96
518_K	522_A	1.376	0.96
161_L	186_I	1.375	0.96
182_F	186_I	1.373	0.96
417_F	422_F	1.360	0.96
458_A	493_N	1.357	0.96
261_Q	264_S	1.356	0.96
267_L	290_L	1.354	0.96
306_A	325_L	1.348	0.95
482_M	504_H	1.348	0.95
165_F	186_I	1.345	0.95
298_F	332_C	1.345	0.95
285_S	288_R	1.339	0.95
104_G	154_A	1.330	0.95
229_T	233_L	1.325	0.95
384_F	402_V	1.318	0.95
286_A	290_L	1.317	0.95
309_M	312_C	1.308	0.95
493_N	510_I	1.299	0.94
58_V	62_I	1.283	0.94
493_N	514_V	1.283	0.94
459_L	521_M	1.282	0.94
102_F	106_A	1.276	0.94
482_M	500_Q	1.264	0.94
321_I	325_L	1.262	0.94
372_V	399_M	1.256	0.93
472_I	514_V	1.250	0.93
259_C	276_C	1.242	0.93
89_L	156_I	1.240	0.93
310_Y	325_L	1.233	0.93
269_I	277_P	1.233	0.93
463_D	484_L	1.230	0.93
470_N	517_V	1.213	0.92
412_Y	416_R	1.202	0.92
454_A	489_A	1.200	0.92
307_L	408_F	1.200	0.92
366_V	369_V	1.200	0.92
346_L	353_Y	1.198	0.92
267_L	270_F	1.194	0.92
265_G	268_T	1.193	0.92
250_T	264_S	1.188	0.91
317_N	430_D	1.188	0.91
351_V	355_I	1.183	0.91
283_S	286_A	1.180	0.91
394_S	397_W	1.177	0.91
265_G	272_A	1.171	0.91
285_S	289_F	1.167	0.91
250_T	254_G	1.161	0.90
447_K	450_Y	1.159	0.90
104_G	191_M	1.158	0.90
111_A	195_G	1.157	0.90
24_L	87_L	1.155	0.90
87_L	98_A	1.144	0.90
419_I	429_R	1.143	0.90
38_I	42_L	1.141	0.90
254_G	258_V	1.140	0.90
351_V	354_V	1.129	0.89
418_A	424_L	1.125	0.89
326_I	329_L	1.124	0.89
231_E	360_T	1.118	0.89
266_A	290_L	1.114	0.88
313_A	426_T	1.112	0.88
451_N	517_V	1.099	0.88
305_A	309_M	1.099	0.88
413_V	417_F	1.098	0.88
515_Q	519_D	1.087	0.87
257_E	262_T	1.084	0.87
141_I	144_I	1.083	0.87
284_E	289_F	1.080	0.87
225_M	365_T	1.072	0.86
296_P	367_M	1.070	0.86
193_L	197_V	1.067	0.86
333_V	381_I	1.066	0.86
309_M	321_I	1.064	0.86
249_F	267_L	1.063	0.86
34_I	38_I	1.062	0.86
465_I	525_M	1.059	0.86
496_I	510_I	1.056	0.86
363_G	407_W	1.054	0.86
221_D	369_V	1.053	0.85
514_V	517_V	1.052	0.85
229_T	358_L	1.046	0.85
362_L	407_W	1.041	0.85
452_V	524_L	1.041	0.85
222_F	435_S	1.039	0.85
317_N	433_V	1.038	0.85
412_Y	420_T	1.038	0.85
220_G	223_G	1.031	0.84
374_I	400_V	1.030	0.84
224_P	288_R	1.024	0.84
256_Q	259_C	1.024	0.84
311_H	315_P	1.024	0.84
68_K	114_F	1.019	0.84
373_T	395_T	1.018	0.83
224_P	368_S	1.014	0.83
302_L	341_L	1.012	0.83
453_P	457_E	1.012	0.83
33_G	331_A	1.011	0.83
284_E	287_T	1.011	0.83
374_I	387_F	1.009	0.83
442_A	445_P	1.009	0.83
265_G	270_F	1.005	0.83
402_V	405_A	1.005	0.83
479_V	487_V	1.002	0.82
248_R	378_D	0.999	0.82
167_N	523_G	0.999	0.82
485_V	506_L	0.998	0.82
520_E	523_G	0.997	0.82
221_D	368_S	0.997	0.82
175_A	337_T	0.997	0.82
396_K	399_M	0.993	0.82
324_L	328_G	0.992	0.82
311_H	318_R	0.983	0.81
266_A	269_I	0.983	0.81
147_G	250_T	0.979	0.81
295_M	298_F	0.976	0.81
478_S	505_N	0.974	0.81
468_L	522_A	0.971	0.80
297_A	301_G	0.967	0.80
307_L	312_C	0.966	0.80
154_A	158_V	0.963	0.80
455_I	517_V	0.963	0.80
225_M	229_T	0.963	0.80
157_I	160_M	0.962	0.80
266_A	273_Q	0.958	0.80
255_T	264_S	0.956	0.79
36_L	74_F	0.955	0.79
263_V	272_A	0.951	0.79
384_F	391_H	0.951	0.79
301_G	411_Y	0.950	0.79
256_Q	260_G	0.949	0.79
451_N	493_N	0.948	0.79
370_L	399_M	0.948	0.79
215_M	219_A	0.947	0.79
458_A	490_L	0.944	0.79
104_G	158_V	0.942	0.78
14_F	160_M	0.941	0.78
86_P	101_G	0.936	0.78
197_V	201_V	0.935	0.78
68_K	71_S	0.934	0.78
208_G	211_G	0.932	0.78
135_I	142_Q	0.929	0.77
297_A	407_W	0.927	0.77
423_N	429_R	0.920	0.77
134_N	138_I	0.920	0.77
434_A	437_I	0.918	0.77
254_G	257_E	0.916	0.76
362_L	366_V	0.916	0.76
122_L	142_Q	0.914	0.76
186_I	189_L	0.913	0.76
168_I	186_I	0.912	0.76
351_V	418_A	0.910	0.76
270_F	273_Q	0.909	0.76
413_V	416_R	0.906	0.76
450_Y	453_P	0.905	0.76
423_N	426_T	0.903	0.75
337_T	472_I	0.903	0.75
463_D	480_K	0.901	0.75
113_N	117_T	0.900	0.75
419_I	428_G	0.898	0.75
310_Y	326_I	0.896	0.75
271_Q	290_L	0.894	0.75
298_F	379_G	0.892	0.75
334_V	382_I	0.889	0.74
480_K	484_L	0.889	0.74
410_V	413_V	0.889	0.74
270_F	277_P	0.888	0.74
375_G	383_D	0.886	0.74
482_M	502_N	0.885	0.74
36_L	382_I	0.883	0.74
255_T	258_V	0.880	0.73
11_L	14_F	0.879	0.73
161_L	165_F	0.878	0.73
482_M	501_L	0.876	0.73
313_A	318_R	0.873	0.73
521_M	524_L	0.872	0.73
358_L	436_S	0.871	0.73
254_G	264_S	0.869	0.73
146_T	150_G	0.867	0.72
190_V	194_V	0.863	0.72
470_N	518_K	0.861	0.72
229_T	361_G	0.861	0.72
171_P	174_L	0.856	0.71
304_G	409_V	0.856	0.71
488_Q	492_D	0.852	0.71
299_L	404_A	0.851	0.71
302_L	328_G	0.848	0.71
43_S	67_S	0.845	0.70
487_V	498_V	0.844	0.70
314_R	432_E	0.843	0.70
266_A	270_F	0.843	0.70
28_L	103_I	0.840	0.70
105_Y	109_N	0.837	0.70
225_M	362_L	0.837	0.70
64_T	67_S	0.836	0.70
359_L	362_L	0.835	0.70
207_M	211_G	0.833	0.69
253_G	260_G	0.832	0.69
307_L	310_Y	0.829	0.69
283_S	287_T	0.829	0.69
231_E	364_F	0.823	0.68
108_M	150_G	0.823	0.68
68_K	75_S	0.823	0.68
384_F	398_Y	0.822	0.68
462_A	525_M	0.821	0.68
228_G	361_G	0.820	0.68
317_N	438_E	0.819	0.68
502_N	505_N	0.817	0.68
316_E	432_E	0.814	0.68
516_S	519_D	0.814	0.68
14_F	18_L	0.813	0.67
79_V	139_L	0.810	0.67
301_G	356_H	0.809	0.67
157_I	191_M	0.807	0.67
366_V	407_W	0.806	0.67
470_N	516_S	0.805	0.67
83_I	98_A	0.802	0.66
307_L	416_R	0.801	0.66
401_P	406_I	0.800	0.66
477_L	501_L	0.800	0.66
384_F	397_W	0.799	0.66
214_H	218_S	0.797	0.66
43_S	46_D	0.797	0.66
138_I	144_I	0.797	0.66
13_E	505_N	0.797	0.66
367_M	371_G	0.796	0.66
454_A	493_N	0.795	0.66
294_K	353_Y	0.793	0.66
181_R	184_P	0.792	0.65
136_Q	145_D	0.790	0.65
468_L	477_L	0.788	0.65
22_F	180_T	0.787	0.65
108_M	198_I	0.787	0.65
452_V	520_E	0.786	0.65
171_P	177_F	0.785	0.65
417_F	424_L	0.782	0.64
384_F	389_I	0.781	0.64
366_V	403_V	0.781	0.64
149_L	246_L	0.780	0.64
106_A	139_L	0.777	0.64
122_L	135_I	0.773	0.64
262_T	265_G	0.772	0.63
314_R	425_K	0.770	0.63
496_I	513_Q	0.767	0.63
94_K	180_T	0.765	0.63
37_G	40_S	0.764	0.63
501_L	505_N	0.763	0.63
273_Q	277_P	0.762	0.62
342_E	345_F	0.761	0.62
455_I	490_L	0.758	0.62
454_A	524_L	0.758	0.62
470_N	515_Q	0.755	0.62
112_V	146_T	0.753	0.61
138_I	142_Q	0.751	0.61
132_A	138_I	0.749	0.61
454_A	492_D	0.748	0.61
140_G	143_S	0.745	0.61
389_I	397_W	0.743	0.60
135_I	140_G	0.743	0.60
253_G	269_I	0.741	0.60
315_P	412_Y	0.741	0.60
47_V	59_L	0.740	0.60
323_G	341_L	0.739	0.60
173_A	330_I	0.738	0.60
471_C	476_R	0.738	0.60
308_A	419_I	0.736	0.60
36_L	71_S	0.735	0.60
73_A	80_M	0.733	0.59
86_P	97_A	0.731	0.59
92_E	162_H	0.731	0.59
320_K	421_R	0.731	0.59
314_R	418_A	0.728	0.59
217_N	247_I	0.728	0.59
498_V	508_V	0.727	0.59
246_L	408_F	0.723	0.58
477_L	508_V	0.722	0.58
16_Q	19_G	0.722	0.58
13_E	451_N	0.722	0.58
453_P	524_L	0.719	0.58
470_N	510_I	0.718	0.58
302_L	411_Y	0.718	0.58
294_K	364_F	0.717	0.58
82_C	151_A	0.713	0.57
268_T	271_Q	0.713	0.57
17_Q	163_E	0.712	0.57
267_L	271_Q	0.711	0.57
137_S	142_Q	0.709	0.57
471_C	474_R	0.708	0.57
469_D	518_K	0.707	0.57
253_G	256_Q	0.707	0.57
446_G	520_E	0.706	0.57
465_I	479_V	0.705	0.56
221_D	365_T	0.703	0.56
260_G	263_V	0.702	0.56
335_G	380_N	0.701	0.56
448_S	514_V	0.701	0.56
213_G	254_G	0.698	0.56
514_V	521_M	0.698	0.56
219_A	226_L	0.698	0.56
144_I	206_A	0.697	0.56
362_L	396_K	0.697	0.56
311_H	413_V	0.696	0.55
329_L	333_V	0.696	0.55
17_Q	467_S	0.695	0.55
13_E	478_S	0.694	0.55
248_R	377_T	0.693	0.55
266_A	271_Q	0.692	0.55
317_N	509_V	0.691	0.55
508_V	514_V	0.691	0.55
259_C	262_T	0.690	0.55
248_R	298_F	0.688	0.55
457_E	509_V	0.688	0.55
108_M	154_A	0.686	0.54
398_Y	505_N	0.686	0.54
510_I	517_V	0.684	0.54
224_P	229_T	0.684	0.54
248_R	379_G	0.682	0.54
456_L	465_I	0.681	0.54
165_F	182_F	0.681	0.54
165_F	168_I	0.680	0.54
472_I	512_P	0.680	0.54
140_G	144_I	0.680	0.54
294_K	379_G	0.679	0.54
137_S	141_I	0.676	0.53
342_E	356_H	0.674	0.53
16_Q	88_G	0.673	0.53
313_A	429_R	0.671	0.53
86_P	159_W	0.670	0.53
466_V	479_V	0.670	0.53
477_L	518_K	0.670	0.53
149_L	200_L	0.669	0.53
302_L	356_H	0.668	0.52
43_S	63_F	0.668	0.52
419_I	427_P	0.662	0.52
458_A	470_N	0.662	0.52
231_E	297_A	0.661	0.52
508_V	517_V	0.661	0.52
448_S	516_S	0.661	0.52
115_W	196_L	0.660	0.52
174_L	377_T	0.660	0.52
516_S	520_E	0.660	0.52
27_A	176_F	0.658	0.51
272_A	276_C	0.657	0.51
64_T	68_K	0.656	0.51
40_S	44_S	0.656	0.51
304_G	384_F	0.652	0.51
162_H	180_T	0.650	0.51
67_S	71_S	0.650	0.51
283_S	289_F	0.649	0.50
87_L	94_K	0.648	0.50
227_F	353_Y	0.648	0.50
255_T	269_I	0.648	0.50
448_S	513_Q	0.647	0.50
135_I	138_I	0.647	0.50
454_A	457_E	0.645	0.50
153_I	198_I	0.643	0.50
84_A	99_F	0.643	0.50
159_W	163_E	0.642	0.50
472_I	496_I	0.641	0.50
162_H	266_A	0.640	0.49
515_Q	522_A	0.638	0.49
237_F	363_G	0.638	0.49
31_F	189_L	0.637	0.49
433_V	488_Q	0.637	0.49
69_I	111_A	0.636	0.49
305_A	415_F	0.635	0.49
448_S	520_E	0.633	0.49
224_P	230_G	0.631	0.48
306_A	329_L	0.631	0.48
142_Q	145_D	0.630	0.48
40_S	47_V	0.630	0.48
513_Q	516_S	0.629	0.48
188_S	191_M	0.628	0.48
443_G	463_D	0.626	0.48
367_M	400_V	0.626	0.48
149_L	153_I	0.625	0.48
474_R	507_Q	0.625	0.48
455_I	493_N	0.625	0.48
253_G	265_G	0.625	0.48
123_P	135_I	0.625	0.48
417_F	420_T	0.624	0.48
520_E	524_L	0.624	0.48
225_M	361_G	0.623	0.48
208_G	212_L	0.623	0.48
82_C	237_F	0.621	0.47
458_A	477_L	0.620	0.47
201_V	204_I	0.619	0.47
445_P	448_S	0.618	0.47
148_I	151_A	0.618	0.47
451_N	454_A	0.617	0.47
215_M	218_S	0.617	0.47
443_G	446_G	0.616	0.47
325_L	426_T	0.616	0.47
475_L	518_K	0.615	0.47
254_G	261_Q	0.613	0.46
512_P	516_S	0.613	0.46
13_E	521_M	0.613	0.46
19_G	22_F	0.612	0.46
213_G	346_L	0.612	0.46
362_L	369_V	0.612	0.46
257_E	265_G	0.610	0.46
201_V	205_F	0.610	0.46
305_A	411_Y	0.609	0.46
406_I	492_D	0.609	0.46
115_W	199_P	0.607	0.46
266_A	287_T	0.607	0.46
151_A	155_G	0.606	0.46
284_E	290_L	0.603	0.45
393_L	397_W	0.603	0.45
237_F	346_L	0.601	0.45
269_I	286_A	0.601	0.45
137_S	140_G	0.600	0.45
172_D	513_Q	0.599	0.45
73_A	525_M	0.598	0.45
189_L	192_G	0.598	0.45
359_L	417_F	0.597	0.45
485_V	508_V	0.596	0.45
273_Q	276_C	0.594	0.44
312_C	424_L	0.594	0.44
105_Y	150_G	0.592	0.44
108_M	195_G	0.592	0.44
409_V	442_A	0.591	0.44
458_A	486_N	0.591	0.44
26_V	40_S	0.589	0.44
299_L	356_H	0.587	0.44
508_V	521_M	0.585	0.43
478_S	504_H	0.584	0.43
406_I	436_S	0.582	0.43
178_G	495_A	0.582	0.43
430_D	433_V	0.582	0.43
134_N	137_S	0.582	0.43
30_S	232_R	0.581	0.43
294_K	346_L	0.580	0.43
305_A	425_K	0.579	0.43
457_E	466_V	0.578	0.43
189_L	483_S	0.578	0.43
169_R	513_Q	0.578	0.43
197_V	200_L	0.578	0.43
70_G	301_G	0.578	0.43
258_V	262_T	0.577	0.43
490_L	495_A	0.577	0.43
261_Q	268_T	0.577	0.43
210_S	214_H	0.577	0.43
95_G	304_G	0.576	0.43
202_W	350_P	0.576	0.43
450_Y	454_A	0.575	0.42
319_H	417_F	0.574	0.42
27_A	248_R	0.574	0.42
498_V	506_L	0.574	0.42
341_L	344_L	0.574	0.42
85_I	152_V	0.574	0.42
254_G	262_T	0.572	0.42
43_S	60_Q	0.571	0.42
74_F	337_T	0.570	0.42
444_A	449_G	0.570	0.42
451_N	499_V	0.570	0.42
181_R	293_G	0.569	0.42
349_A	424_L	0.568	0.42
268_T	326_I	0.568	0.42
90_A	93_N	0.568	0.42
331_A	344_L	0.568	0.42
366_V	370_L	0.567	0.42
207_M	358_L	0.566	0.41
187_S	191_M	0.566	0.41
295_M	387_F	0.565	0.41
112_V	198_I	0.564	0.41
178_G	182_F	0.563	0.41
98_A	101_G	0.563	0.41
138_I	145_D	0.561	0.41
444_A	523_G	0.560	0.41
246_L	376_N	0.560	0.41
421_R	523_G	0.560	0.41
372_V	403_V	0.560	0.41
512_P	519_D	0.559	0.41
501_L	508_V	0.559	0.41
297_A	304_G	0.559	0.41
295_M	378_D	0.558	0.41
133_N	137_S	0.558	0.41
230_G	361_G	0.558	0.41
453_P	483_S	0.557	0.41
16_Q	469_D	0.555	0.40
88_G	247_I	0.555	0.40
305_A	356_H	0.555	0.40
31_F	325_L	0.553	0.40
294_K	360_T	0.552	0.40
483_S	492_D	0.551	0.40
133_N	141_I	0.550	0.40
96_V	518_K	0.550	0.40
48_I	59_L	0.549	0.40
109_N	141_I	0.548	0.40
490_L	498_V	0.547	0.39
434_A	438_E	0.547	0.39
499_V	521_M	0.547	0.39
316_E	433_V	0.546	0.39
486_N	490_L	0.546	0.39
265_G	273_Q	0.546	0.39
448_S	451_N	0.545	0.39
135_I	139_L	0.545	0.39
301_G	305_A	0.544	0.39
446_G	449_G	0.543	0.39
465_I	468_L	0.543	0.39
203_P	241_H	0.542	0.39
228_G	360_T	0.542	0.39
315_P	319_H	0.541	0.39
256_Q	273_Q	0.540	0.39
112_V	199_P	0.539	0.39
31_F	187_S	0.538	0.39
216_I	223_G	0.538	0.39
328_G	332_C	0.538	0.39
445_P	449_G	0.537	0.38
42_L	63_F	0.537	0.38
288_R	292_Q	0.537	0.38
265_G	271_Q	0.536	0.38
216_I	253_G	0.536	0.38
91_R	163_E	0.535	0.38
269_I	397_W	0.535	0.38
383_D	386_V	0.534	0.38
312_C	318_R	0.533	0.38
438_E	445_P	0.532	0.38
205_F	208_G	0.531	0.38
276_C	283_S	0.531	0.38
157_I	186_I	0.530	0.38
16_Q	20_K	0.529	0.38
49_T	62_I	0.529	0.38
42_L	48_I	0.529	0.38
244_V	267_L	0.529	0.38
18_L	166_H	0.528	0.38
243_L	294_K	0.527	0.37
212_L	230_G	0.526	0.37
296_P	400_V	0.526	0.37
45_H	49_T	0.526	0.37
91_R	462_A	0.526	0.37
78_P	136_Q	0.525	0.37
385_V	455_I	0.524	0.37
478_S	482_M	0.524	0.37
109_N	144_I	0.523	0.37
303_P	408_F	0.523	0.37
462_A	509_V	0.522	0.37
270_F	387_F	0.522	0.37
244_V	360_T	0.522	0.37
263_V	267_L	0.522	0.37
30_S	35_M	0.522	0.37
247_I	298_F	0.521	0.37
161_L	191_M	0.521	0.37
473_T	509_V	0.521	0.37
301_G	359_L	0.520	0.37
391_H	397_W	0.520	0.37
31_F	322_K	0.520	0.37
312_C	412_Y	0.520	0.37
90_A	243_L	0.520	0.37
449_G	465_I	0.520	0.37
48_I	58_V	0.519	0.37
103_I	185_I	0.519	0.37
380_N	383_D	0.518	0.36
206_A	210_S	0.517	0.36
105_Y	149_L	0.517	0.36
165_F	183_V	0.517	0.36
454_A	462_A	0.517	0.36
248_R	295_M	0.516	0.36
298_F	378_D	0.516	0.36
154_A	198_I	0.515	0.36
245_A	248_R	0.515	0.36
250_T	255_T	0.515	0.36
58_V	61_A	0.515	0.36
162_H	287_T	0.514	0.36
233_L	346_L	0.514	0.36
35_M	159_W	0.514	0.36
292_Q	367_M	0.513	0.36
196_L	199_P	0.513	0.36
119_K	122_L	0.513	0.36
94_K	162_H	0.512	0.36
448_S	456_L	0.511	0.36
451_N	455_I	0.511	0.36
381_I	398_Y	0.510	0.36
362_L	486_N	0.510	0.36
134_N	141_I	0.509	0.36
299_L	384_F	0.508	0.35
32_C	377_T	0.508	0.35
371_G	395_T	0.508	0.35
325_L	344_L	0.508	0.35
521_M	525_M	0.508	0.35
415_F	428_G	0.508	0.35
378_D	383_D	0.508	0.35
92_E	518_K	0.507	0.35
288_R	373_T	0.507	0.35
174_L	186_I	0.507	0.35
442_A	447_K	0.506	0.35
158_V	183_V	0.504	0.35
456_L	498_V	0.504	0.35
466_V	524_L	0.504	0.35
330_I	512_P	0.503	0.35
463_D	523_G	0.503	0.35
118_N	122_L	0.503	0.35
104_G	184_P	0.502	0.35
79_V	106_A	0.502	0.35
288_R	368_S	0.500	0.35
43_S	59_L	0.500	0.35
146_T	202_W	0.500	0.35
476_R	507_Q	0.500	0.35
358_L	417_F	0.500	0.35
355_I	410_V	0.500	0.35

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3qnqA	2	0.7528	100	0.7	Contact Map
1ibaA	1	0.1472	99.9	0.844	Contact Map
3bp3A	1	0.1528	99.9	0.846	Contact Map
3ipjA	1	0.1604	99.9	0.857	Contact Map
4ea3A	2	0.1623	49.6	0.975	Contact Map
3wdoA	1	0.8019	44.3	0.976	Contact Map
4pypA	1	0.6774	25.1	0.979	Contact Map
4cbcA	3	0.166	18.4	0.98	Contact Map
2b1eA	1	0.1623	18.3	0.98	Contact Map
3hjlA	1	0.1623	15.2	0.981	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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