GREMLIN Database
GGT - Gamma-glutamyltranspeptidase
UniProt: P18956 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10374
Length: 580 (518)
Sequences: 5246 (3656)
Seq/√Len: 160.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
178_R232_E7.0911.00
240_D244_K4.3361.00
309_N364_A4.2571.00
68_E168_K3.7691.00
249_E264_K3.7001.00
175_K179_D3.6011.00
50_M566_G3.5561.00
305_N360_A3.5501.00
53_S59_T3.1521.00
113_F153_G3.0541.00
53_S79_V2.9921.00
282_Y500_D2.7901.00
252_A264_K2.7681.00
327_A523_L2.7481.00
188_A218_K2.5241.00
305_N357_K2.5001.00
504_N507_E2.4121.00
283_R500_D2.3761.00
82_A176_L2.3721.00
308_E357_K2.3271.00
497_N503_L2.3041.00
505_V555_S2.2951.00
155_S159_D2.2771.00
62_G79_V2.2421.00
81_Y170_V2.2311.00
309_N361_K2.2311.00
214_E220_D2.2191.00
174_F235_A2.2091.00
536_L540_K2.2021.00
320_A536_L2.1971.00
111_I274_E2.1971.00
171_Q175_K2.1861.00
99_M157_A2.1751.00
51_V62_G2.1691.00
321_D540_K2.1661.00
155_S239_P2.1621.00
288_Y470_V2.1541.00
255_M260_G2.1351.00
156_L272_A2.1141.00
281_D286_Q2.1091.00
403_A478_V2.1001.00
303_I492_L2.0921.00
79_V394_Y2.0811.00
241_E247_I2.0791.00
109_T161_Y2.0721.00
535_K538_E2.0711.00
324_Q542_Q2.0641.00
279_S286_Q2.0031.00
48_Q399_K1.9921.00
160_K274_E1.9641.00
244_K268_A1.9501.00
233_M246_T1.9421.00
226_N422_E1.9391.00
509_T555_S1.9191.00
495_V499_I1.8991.00
237_N241_E1.8681.00
217_K220_D1.8551.00
64_D67_K1.8551.00
469_V495_V1.8471.00
107_N276_T1.8441.00
110_A290_M1.8391.00
368_D371_K1.8251.00
233_M237_N1.8181.00
273_V345_D1.8091.00
306_I329_A1.8081.00
397_V564_L1.8031.00
73_V157_A1.7921.00
232_E236_E1.7871.00
280_G301_V1.7841.00
59_T578_A1.7831.00
265_E269_A1.7781.00
152_A272_A1.7741.00
156_L159_D1.7671.00
77_V158_L1.7541.00
167_N236_E1.7521.00
233_M241_E1.7491.00
249_E253_Q1.7471.00
279_S288_Y1.7341.00
178_R229_K1.7281.00
119_A269_A1.7111.00
64_D68_E1.6911.00
250_Q423_S1.6901.00
397_V403_A1.6741.00
60_Q64_D1.6711.00
362_S365_D1.6651.00
506_A510_N1.6551.00
51_V79_V1.6381.00
151_V234_I1.6361.00
477_L557_M1.6361.00
395_S478_V1.6341.00
506_A567_A1.6291.00
86_T181_F1.6241.00
477_L498_S1.6231.00
510_N570_P1.6191.00
211_K216_L1.6151.00
252_A256_Q1.5881.00
163_T400_D1.5641.00
102_R108_T1.5631.00
325_I369_I1.5551.00
322_A501_Y1.5451.00
64_D175_K1.5401.00
403_A475_T1.5331.00
158_L169_V1.5311.00
116_M270_Y1.5081.00
233_M247_I1.5021.00
158_L166_L1.4951.00
79_V396_V1.4901.00
142_H255_M1.4881.00
252_A263_T1.4861.00
46_A579_G1.4831.00
496_V500_D1.4761.00
170_V174_F1.4751.00
534_L538_E1.4711.00
103_S402_N1.4671.00
65_I164_M1.4631.00
494_M553_T1.4581.00
120_K263_T1.4461.00
97_G153_G1.4461.00
300_I465_S1.4441.00
182_I221_T1.4431.00
409_T430_Q1.4411.00
311_D314_K1.4381.00
185_D218_K1.4361.00
552_S572_S1.4241.00
280_G305_N1.4211.00
156_L274_E1.4181.00
98_F293_P1.4151.00
165_P168_K1.4111.00
117_A457_N1.4061.00
73_V101_I1.4021.00
104_K402_N1.3991.00
204_N207_A1.3981.00
363_I366_Q1.3831.00
196_S200_P1.3811.00
324_Q328_E1.3791.00
120_K261_L1.3751.00
145_S427_L1.3711.00
315_Y325_I1.3711.00
174_F232_E1.3681.00
253_Q257_K1.3641.00
298_I341_L1.3581.00
361_K364_A1.3551.00
557_M565_Y1.3551.00
536_L539_A1.3541.00
65_I68_E1.3521.00
328_E331_K1.3491.00
310_F364_A1.3481.00
152_A239_P1.3431.00
155_S166_L1.3431.00
102_R106_G1.3401.00
63_V67_K1.3381.00
525_V534_L1.3331.00
152_A240_D1.3281.00
305_N308_E1.3271.00
287_V469_V1.3211.00
378_I381_G1.3211.00
255_M262_I1.3111.00
264_K268_A1.3091.00
141_S418_I1.3061.00
108_T288_Y1.3031.00
281_D284_G1.3031.00
558_V564_L1.2961.00
52_A554_Q1.2841.00
110_A291_P1.2811.00
522_E545_A1.2731.00
158_L163_T1.2721.00
497_N501_Y1.2691.00
246_T249_E1.2661.00
535_K539_A1.2611.00
97_G113_F1.2601.00
112_D275_R1.2581.00
269_A457_N1.2581.00
493_Q513_R1.2491.00
531_P535_K1.2471.00
63_V578_A1.2431.00
498_S557_M1.2391.00
559_G565_Y1.2321.00
534_L544_V1.2321.00
420_A423_S1.2301.00
285_Y476_W1.2211.00
65_I169_V1.2171.00
109_T160_K1.2141.00
323_M327_A1.2111.00
202_H205_S1.2081.00
100_L110_A1.2041.00
147_T262_I1.2031.00
119_A457_N1.2001.00
368_D372_A1.2001.00
73_V404_V1.1991.00
73_V402_N1.1991.00
61_V82_A1.1971.00
332_Y366_Q1.1931.00
503_L511_A1.1881.00
168_K171_Q1.1871.00
420_A427_L1.1821.00
497_N511_A1.1761.00
300_I492_L1.1631.00
211_K220_D1.1531.00
311_D315_Y1.1531.00
285_Y499_I1.1521.00
101_I157_A1.1511.00
303_I329_A1.1481.00
68_E164_M1.1421.00
346_F458_K1.1411.00
321_D369_I1.1411.00
111_I272_A1.1351.00
142_H258_N1.1341.00
303_I330_E1.1281.00
307_L492_L1.1281.00
498_S505_V1.1271.00
265_E268_A1.1241.00
203_E207_A1.1221.00
109_T274_E1.1211.00
111_I161_Y1.1161.00
102_R470_V1.1161.00
207_A226_N1.1131.00
244_K248_A1.1121.00
336_D363_I1.1111.00
43_P504_N1.1091.00
320_A540_K1.0991.00
310_F325_I1.0991.00
111_I157_A1.0961.00
71_N163_T1.0911.00
178_R225_A1.0880.99
336_D359_Y1.0870.99
116_M457_N1.0860.99
216_L220_D1.0800.99
476_W557_M1.0800.99
254_E420_A1.0790.99
156_L271_K1.0780.99
230_S425_I1.0760.99
470_V475_T1.0750.99
323_M533_T1.0740.99
357_K361_K1.0730.99
152_A156_L1.0700.99
328_E542_Q1.0680.99
76_A404_V1.0670.99
534_L546_L1.0650.99
280_G357_K1.0640.99
58_A83_L1.0590.99
102_R105_N1.0570.99
166_L169_V1.0570.99
353_A383_L1.0560.99
320_A533_T1.0550.99
394_Y406_V1.0500.99
65_I78_A1.0480.99
77_V154_F1.0480.99
171_Q174_F1.0460.99
287_V304_L1.0450.99
156_L160_K1.0430.99
119_A265_E1.0420.99
475_T478_V1.0420.99
77_V169_V1.0420.99
112_D293_P1.0420.99
166_L170_V1.0400.99
151_V239_P1.0400.99
64_D172_P1.0400.99
206_K210_W1.0400.99
286_Q470_V1.0330.99
158_L165_P1.0330.99
123_R453_A1.0250.99
99_M153_G1.0250.99
478_V556_I1.0240.99
505_V567_A1.0220.99
49_G66_L1.0190.99
393_H405_A1.0180.99
479_T494_M1.0180.99
312_M315_Y1.0170.99
229_K232_E1.0150.99
455_G458_K1.0140.99
53_S62_G1.0140.99
65_I168_K1.0140.99
121_A125_M1.0120.99
322_A326_M1.0030.99
433_D485_S0.9980.99
262_I267_L0.9980.99
149_G270_Y0.9950.99
319_S322_A0.9940.99
45_R565_Y0.9910.99
65_I172_P0.9890.99
246_T250_Q0.9880.99
188_A217_K0.9860.99
302_Q336_D0.9850.99
410_L426_L0.9850.99
301_V355_T0.9850.99
250_Q253_Q0.9840.99
306_I309_N0.9810.99
114_R293_P0.9800.99
397_V556_I0.9790.99
80_G408_Y0.9790.99
55_D86_T0.9780.99
522_E543_K0.9740.99
247_I250_Q0.9710.99
230_S423_S0.9680.99
123_R455_G0.9680.99
285_Y471_K0.9620.99
316_G319_S0.9610.99
84_A227_L0.9590.99
303_I333_A0.9530.99
54_V87_H0.9500.99
347_V350_P0.9480.99
145_S418_I0.9480.99
224_Q425_I0.9460.99
248_A267_L0.9450.99
403_A468_I0.9430.99
474_K558_V0.9410.99
52_A568_S0.9370.98
60_Q67_K0.9340.98
152_A155_S0.9340.98
192_K217_K0.9330.98
214_E217_K0.9330.98
481_S490_T0.9320.98
50_M556_I0.9310.98
250_Q422_E0.9280.98
283_R310_F0.9260.98
304_L495_V0.9250.98
61_V173_A0.9250.98
76_A396_V0.9240.98
509_T553_T0.9230.98
332_Y363_I0.9230.98
566_G577_T0.9230.98
81_Y151_V0.9160.98
50_M564_L0.9150.98
230_S247_I0.9130.98
306_I364_A0.9120.98
486_R490_T0.9110.98
298_I351_W0.9100.98
229_K236_E0.9070.98
322_A496_V0.9050.98
312_M496_V0.9020.98
187_L191_L0.9010.98
178_R228_A0.9010.98
525_V544_V0.9010.98
323_M529_F0.8990.98
393_H480_G0.8980.98
82_A86_T0.8930.98
251_I427_L0.8920.98
164_M168_K0.8910.98
208_I224_Q0.8900.98
46_A50_M0.8890.98
57_T61_V0.8830.98
229_K233_M0.8820.98
127_L438_P0.8790.98
452_N458_K0.8790.98
158_L164_M0.8780.98
183_V188_A0.8770.98
117_A121_A0.8740.98
252_A255_M0.8740.98
61_V78_A0.8740.98
439_G453_A0.8730.98
113_F406_V0.8710.98
188_A192_K0.8700.98
398_D402_N0.8690.98
469_V477_L0.8690.98
392_T408_Y0.8630.97
211_K214_E0.8610.97
248_A264_K0.8600.97
52_A556_I0.8590.97
283_R308_E0.8570.97
145_S416_T0.8550.97
111_I156_L0.8520.97
321_D325_I0.8500.97
121_A261_L0.8500.97
435_S453_A0.8480.97
479_T555_S0.8450.97
125_M129_D0.8430.97
306_I367_I0.8420.97
530_S534_L0.8400.97
254_E257_K0.8400.97
281_D308_E0.8400.97
524_R545_A0.8370.97
91_G408_Y0.8350.97
59_T576_L0.8350.97
185_D189_D0.8350.97
357_K360_A0.8340.97
164_M169_V0.8340.97
43_P565_Y0.8330.97
227_L231_L0.8300.97
165_P169_V0.8290.97
143_L261_L0.8290.97
103_S106_G0.8290.97
525_V546_L0.8270.97
533_T536_L0.8230.97
530_S533_T0.8220.97
205_S426_L0.8200.96
538_E543_K0.8170.96
467_T479_T0.8150.96
397_V558_V0.8150.96
85_V173_A0.8140.96
85_V177_A0.8120.96
203_E206_K0.8120.96
342_G460_P0.8070.96
111_I160_K0.8050.96
254_E258_N0.8030.96
84_A231_L0.8020.96
437_K440_V0.8000.96
319_S501_Y0.7970.96
116_M345_D0.7970.96
234_I239_P0.7970.96
255_M427_L0.7960.96
247_I425_I0.7960.96
356_N360_A0.7950.96
525_V529_F0.7920.96
346_F455_G0.7890.96
489_T515_H0.7870.96
280_G360_A0.7860.96
97_G406_V0.7850.95
146_G431_M0.7840.95
104_K400_D0.7840.95
115_E430_Q0.7820.95
50_M579_G0.7800.95
121_A126_F0.7760.95
538_E546_L0.7760.95
183_V222_L0.7720.95
283_R499_I0.7720.95
281_D357_K0.7710.95
210_W216_L0.7690.95
503_L507_E0.7680.95
224_Q227_L0.7680.95
57_T86_T0.7670.95
61_V65_I0.7660.95
411_N433_D0.7660.95
277_P288_Y0.7650.95
94_G425_I0.7650.95
85_V227_L0.7620.95
123_R127_L0.7620.95
124_D127_L0.7590.95
254_E418_I0.7590.95
116_M273_V0.7560.94
142_H254_E0.7550.94
326_M514_F0.7550.94
516_H520_P0.7550.94
323_M514_F0.7530.94
258_N418_I0.7520.94
278_I289_S0.7510.94
359_Y363_I0.7480.94
330_E492_L0.7470.94
285_Y469_V0.7470.94
80_G394_Y0.7460.94
66_L396_V0.7450.94
183_V187_L0.7450.94
183_V216_L0.7440.94
307_L312_M0.7430.94
556_I564_L0.7420.94
420_A425_I0.7410.94
120_K256_Q0.7390.94
435_S438_P0.7380.94
62_G396_V0.7370.94
57_T176_L0.7350.94
468_I475_T0.7330.94
289_S491_V0.7330.94
177_A228_A0.7320.93
437_K453_A0.7310.93
306_I360_A0.7300.93
300_I491_V0.7270.93
289_S467_T0.7260.93
47_K563_E0.7250.93
517_Q520_P0.7240.93
174_F178_R0.7240.93
101_I404_V0.7230.93
125_M261_L0.7220.93
368_D373_K0.7210.93
306_I363_I0.7200.93
225_A229_K0.7200.93
230_S233_M0.7170.93
324_Q367_I0.7160.93
321_D536_L0.7160.93
184_N574_D0.7160.93
157_A404_V0.7150.93
78_A169_V0.7150.93
412_T429_N0.7150.93
477_L505_V0.7150.93
275_R291_P0.7140.93
148_P427_L0.7120.93
100_L468_I0.7120.93
241_E246_T0.7110.92
79_V82_A0.7110.92
313_K502_G0.7100.92
361_K365_D0.7100.92
330_E489_T0.7070.92
411_N432_D0.7040.92
61_V176_L0.7030.92
255_M258_N0.7020.92
476_W498_S0.7020.92
469_V499_I0.7020.92
51_V66_L0.7000.92
505_V565_Y0.6980.92
57_T182_I0.6960.92
101_I402_N0.6950.92
529_F534_L0.6950.92
289_S300_I0.6940.92
96_G115_E0.6930.91
121_A454_V0.6930.91
59_T79_V0.6930.91
289_S465_S0.6930.91
226_N229_K0.6930.91
93_L151_V0.6930.91
251_I267_L0.6920.91
256_Q263_T0.6900.91
324_Q331_K0.6890.91
287_V467_T0.6880.91
138_S436_A0.6880.91
250_Q420_A0.6870.91
318_G322_A0.6850.91
46_A49_G0.6850.91
240_D268_A0.6850.91
498_S502_G0.6840.91
59_T63_V0.6830.91
55_D184_N0.6820.91
471_K474_K0.6820.91
80_G406_V0.6810.91
471_K476_W0.6800.91
126_F141_S0.6800.91
77_V170_V0.6770.91
57_T60_Q0.6740.90
554_Q568_S0.6720.90
342_G347_V0.6710.90
373_K378_I0.6710.90
87_H552_S0.6690.90
98_F294_S0.6690.90
98_F462_S0.6690.90
124_D128_D0.6680.90
397_V478_V0.6680.90
317_F503_L0.6680.90
173_A177_A0.6670.90
60_Q63_V0.6660.90
516_H523_L0.6660.90
141_S416_T0.6640.90
282_Y312_M0.6630.90
280_G308_E0.6610.89
81_Y166_L0.6610.89
205_S419_V0.6600.89
326_M496_V0.6600.89
247_I251_I0.6580.89
109_T276_T0.6570.89
290_M294_S0.6550.89
275_R345_D0.6550.89
49_G63_V0.6550.89
208_I419_V0.6540.89
490_T553_T0.6510.89
117_A434_F0.6510.89
278_I341_L0.6500.89
568_S577_T0.6500.89
490_T551_G0.6490.89
378_I383_L0.6480.89
139_L412_T0.6460.88
310_F367_I0.6450.88
93_L234_I0.6450.88
364_A367_I0.6440.88
436_A454_V0.6420.88
353_A356_N0.6420.88
191_L216_L0.6410.88
155_S158_L0.6400.88
150_T408_Y0.6400.88
428_N431_M0.6400.88
479_T495_V0.6390.88
509_T567_A0.6380.88
171_Q235_A0.6370.88
104_K107_N0.6340.87
204_N421_G0.6330.87
316_G322_A0.6330.87
531_P546_L0.6330.87
286_Q473_G0.6330.87
140_T198_V0.6310.87
142_H418_I0.6310.87
202_H419_V0.6310.87
82_A173_A0.6300.87
369_I540_K0.6280.87
115_E146_G0.6280.87
242_F248_A0.6280.87
60_Q578_A0.6260.87
81_Y154_F0.6250.87
197_E200_P0.6250.87
125_M128_D0.6240.87
152_A270_Y0.6190.86
559_G563_E0.6180.86
108_T470_V0.6180.86
102_R475_T0.6180.86
368_D540_K0.6180.86
59_T577_T0.6160.86
202_H416_T0.6160.86
329_A367_I0.6160.86
98_F114_R0.6150.86
375_S380_P0.6150.86
256_Q262_I0.6140.86
87_H90_A0.6100.85
532_D535_K0.6100.85
247_I423_S0.6090.85
498_S508_A0.6070.85
337_R341_L0.6040.85
299_H333_A0.6040.85
358_A362_S0.6020.85
83_L392_T0.6010.85
332_Y373_K0.6000.84
302_Q306_I0.6000.84
72_A404_V0.5990.84
486_R515_H0.5980.84
80_G150_T0.5970.84
126_F144_A0.5960.84
568_S572_S0.5960.84
155_S238_G0.5960.84
181_F222_L0.5950.84
329_A333_A0.5950.84
191_L210_W0.5950.84
493_Q497_N0.5950.84
237_N246_T0.5930.84
505_V509_T0.5920.84
465_S491_V0.5910.84
190_D413_T0.5910.84
101_I109_T0.5900.83
307_L325_I0.5890.83
395_S556_I0.5890.83
328_E367_I0.5880.83
84_A92_N0.5880.83
116_M119_A0.5860.83
118_P121_A0.5860.83
397_V475_T0.5850.83
80_G154_F0.5850.83
163_T169_V0.5850.83
403_A558_V0.5840.83
77_V162_G0.5830.83
302_Q359_Y0.5830.83
99_M113_F0.5830.83
119_A263_T0.5820.83
467_T495_V0.5820.83
221_T563_E0.5820.83
241_E244_K0.5810.83
141_S144_A0.5800.82
430_Q463_S0.5790.82
303_I489_T0.5790.82
204_N254_E0.5780.82
255_M267_L0.5780.82
49_G399_K0.5770.82
393_H407_T0.5770.82
115_E463_S0.5770.82
61_V64_D0.5770.82
486_R550_M0.5770.82
62_G78_A0.5760.82
496_V501_Y0.5760.82
128_D135_S0.5740.82
317_F501_Y0.5740.82
71_N400_D0.5730.82
144_A416_T0.5730.82
315_Y319_S0.5730.82
209_F224_Q0.5720.82
84_A91_G0.5720.82
479_T491_V0.5710.81
526_E571_R0.5710.81
187_L222_L0.5700.81
313_K316_G0.5690.81
486_R489_T0.5680.81
252_A262_I0.5670.81
150_T409_T0.5670.81
303_I488_I0.5660.81
324_Q540_K0.5650.81
170_V235_A0.5640.81
251_I425_I0.5640.81
324_Q369_I0.5640.81
309_N357_K0.5640.81
73_V103_S0.5630.81
138_S141_S0.5630.81
307_L326_M0.5620.80
54_V392_T0.5620.80
114_R433_D0.5610.80
253_Q422_E0.5610.80
527_K546_L0.5600.80
90_A410_L0.5600.80
334_Y488_I0.5590.80
218_K221_T0.5580.80
299_H341_L0.5580.80
326_M329_A0.5580.80
112_D273_V0.5580.80
419_V426_L0.5570.80
355_T360_A0.5570.80
155_S169_V0.5570.80
83_L394_Y0.5570.80
65_I79_V0.5560.80
197_E201_N0.5550.80
362_S366_Q0.5540.79
317_F322_A0.5520.79
407_T487_I0.5510.79
124_D438_P0.5510.79
62_G82_A0.5490.79
96_G114_R0.5480.79
100_L290_M0.5470.79
299_H337_R0.5440.78
315_Y322_A0.5440.78
152_A244_K0.5430.78
139_L432_D0.5430.78
89_Q187_L0.5430.78
114_R462_S0.5420.78
100_L277_P0.5420.78
117_A455_G0.5410.78
498_S555_S0.5400.78
146_G428_N0.5390.78
71_N164_M0.5390.78
122_T125_M0.5390.78
312_M501_Y0.5390.78
99_M404_V0.5380.77
242_F247_I0.5380.77
223_V226_N0.5370.77
101_I161_Y0.5350.77
43_P567_A0.5350.77
118_P260_G0.5350.77
116_M459_R0.5340.77
481_S551_G0.5340.77
114_R430_Q0.5340.77
87_H91_G0.5340.77
278_I301_V0.5330.77
228_A232_E0.5320.77
359_Y381_G0.5320.77
430_Q487_I0.5310.77
179_D232_E0.5300.76
78_A173_A0.5300.76
407_T462_S0.5300.76
514_F529_F0.5290.76
433_D463_S0.5290.76
475_T558_V0.5270.76
73_V99_M0.5270.76
153_G272_A0.5270.76
97_G150_T0.5270.76
96_G462_S0.5260.76
396_V404_V0.5260.76
93_L425_I0.5250.76
275_R290_M0.5240.76
302_Q360_A0.5240.76
52_A577_T0.5240.76
205_S210_W0.5230.75
61_V172_P0.5220.75
61_V86_T0.5220.75
87_H92_N0.5210.75
261_L454_V0.5210.75
123_R454_V0.5200.75
254_E421_G0.5200.75
289_S488_I0.5190.75
283_R311_D0.5190.75
95_G428_N0.5190.75
326_M330_E0.5190.75
395_S405_A0.5170.75
47_K221_T0.5170.75
136_K139_L0.5160.75
137_K143_L0.5160.75
232_E235_A0.5160.75
234_I241_E0.5150.74
226_N419_V0.5150.74
280_G355_T0.5140.74
316_G501_Y0.5140.74
188_A215_P0.5140.74
299_H338_S0.5130.74
189_D193_T0.5120.74
482_P572_S0.5120.74
192_K215_P0.5120.74
210_W215_P0.5120.74
100_L108_T0.5110.74
199_L205_S0.5100.74
105_N108_T0.5100.74
477_L555_S0.5090.74
89_Q190_D0.5090.74
58_A82_A0.5090.74
312_M325_I0.5080.73
116_M269_A0.5080.73
476_W558_V0.5060.73
515_H520_P0.5060.73
294_S464_M0.5060.73
317_F497_N0.5050.73
452_N461_L0.5030.73
145_S255_M0.5030.73
411_N517_Q0.5030.73
101_I274_E0.5030.73
500_D503_L0.5020.73
306_I365_D0.5020.73
295_S488_I0.5020.73
490_T550_M0.5020.73
297_G341_L0.5010.72
315_Y321_D0.5010.72
101_I111_I0.5000.72
161_Y274_E0.5000.72
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2e0wA 1 0.8638 100 0.037 Contact Map
2nlzA 4 0.9034 100 0.087 Contact Map
2i3oA 2 0.8724 100 0.106 Contact Map
3whrA 1 0.6155 100 0.372 Contact Map
2dg5A 1 0.6034 100 0.404 Contact Map
2qmcA 1 0.5983 100 0.413 Contact Map
4gdxA 1 0.5759 100 0.422 Contact Map
3g9kL 1 0.4897 100 0.457 Contact Map
2dg5B 1 0.3276 100 0.648 Contact Map
4gdxB 1 0.3224 100 0.655 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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