RSTB - ECOLI - GREMLIN Contacts

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RSTB - Sensor protein RstB

UniProt:	P18392	Sequences: MKKLFIQFYLLLFVCFLVMSLLVGLVYKFTAERAGKQSLDDLMNSSLYLMRSELREIPPHDWGKTLKEMDLNLSFDLRVEPLSKYHLDDISMHRLRGGEIVALDDQYTFLQRIPRSHYVLAVGPVPYLYYLHQMRLLDIALIAFIAISLAFPVFIWMRPHWQDMLKLEAAAQRFGDGHLNERIHFDEGSSFERLGVAFNQMADNINALIASKKQLIDGIAHELRTPLVRLRYRLEMSDNLSAAESQALNRDISQLEALIEELLTYARLDRPQNELHLSEPDLPLWLSTHLADIQAVTPDKTVRIKTLVQGHYAALDMRLMERVLDNLLNNALRYCHSTVETSLLLSGNRATLIVEDDGPGIAPENREHIFEPFVRLDPSRDRSTGGCGLGLAIVHSIALAMGGTVNCDTSELGGARFSFSWPLWHNIPQFTSA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11233
Length:	433 (399)
Sequences:	50327 (42486)
Seq/√Len:	2126.9

ECOLI - RSTB BARA CPXA ENVZ BAES PHOQ GLRK CUSS TORS CREC YEDV QSEC RCSC RCSD ATOS ZRAS EVGS BASS DCUS ARCB NARX DPIB NARQ KDPD PHOR YPDA NTRB
BACSU - YCLK YKOH PHOR CSSS YYCG RESE YVRG YVCQ KINB DCTS YRKQ MALK CITS BCES YXDK KIND KINE YCBM YESM KINA GLNK LYTS KINC LIAS YBDK YWPD COMP NATK YFIJ DEGS
HALSA - Q9HQ15 Q9HQE9 Q9HQG5 Q9HQ16 Q9HRE4 Q9HR10 O51970 Q9HNM2 Q9HRG1 BAT Q9HNA6 Q9HQB9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
356_D	360_G	4.034	1.00
355_E	416_R	3.961	1.00
395_H	399_L	3.630	1.00
280_P	315_L	3.375	1.00
349_R	420_S	3.299	1.00
234_L	248_L	3.251	1.00
406_N	418_S	3.244	1.00
353_I	416_R	2.951	1.00
366_R	409_T	2.901	1.00
335_C	357_D	2.894	1.00
315_L	401_M	2.801	1.00
342_S	353_I	2.726	1.00
351_T	420_S	2.716	1.00
338_T	357_D	2.667	1.00
353_I	418_S	2.634	1.00
410_S	413_G	2.553	1.00
344_L	351_T	2.536	1.00
407_C	417_F	2.511	1.00
340_E	355_E	2.498	1.00
351_T	418_S	2.497	1.00
305_K	338_T	2.491	1.00
305_K	340_E	2.487	1.00
362_A	365_N	2.486	1.00
279_E	314_A	2.452	1.00
323_V	398_A	2.450	1.00
394_V	405_V	2.422	1.00
231_R	253_S	2.408	1.00
189_S	192_E	2.406	1.00
408_D	416_R	2.374	1.00
370_F	405_V	2.331	1.00
408_D	418_S	2.315	1.00
342_S	355_E	2.304	1.00
398_A	403_G	2.297	1.00
344_L	353_I	2.261	1.00
409_T	415_A	2.244	1.00
366_R	407_C	2.244	1.00
361_I	369_I	2.236	1.00
307_L	342_S	2.218	1.00
279_E	312_Y	2.161	1.00
365_N	368_H	2.125	1.00
281_D	284_L	2.108	1.00
288_T	321_E	2.063	1.00
231_R	252_I	2.054	1.00
404_T	420_S	2.032	1.00
278_S	317_M	2.031	1.00
307_L	340_E	2.003	1.00
398_A	419_F	2.003	1.00
187_E	192_E	1.990	1.00
368_H	371_E	1.966	1.00
303_R	338_T	1.950	1.00
238_D	249_N	1.927	1.00
323_V	397_I	1.908	1.00
231_R	256_E	1.900	1.00
118_Y	121_A	1.892	1.00
201_M	205_I	1.863	1.00
315_L	320_M	1.842	1.00
297_T	332_L	1.841	1.00
397_I	401_M	1.833	1.00
173_R	178_H	1.819	1.00
293_I	325_D	1.818	1.00
346_S	351_T	1.782	1.00
363_P	366_R	1.773	1.00
256_E	260_E	1.766	1.00
365_N	374_V	1.747	1.00
214_Q	218_G	1.728	1.00
361_I	365_N	1.718	1.00
406_N	420_S	1.715	1.00
399_L	404_T	1.712	1.00
323_V	394_V	1.689	1.00
361_I	415_A	1.680	1.00
368_H	374_V	1.678	1.00
234_L	249_N	1.669	1.00
81_P	85_Y	1.661	1.00
238_D	246_Q	1.648	1.00
277_L	314_A	1.644	1.00
324_L	352_L	1.640	1.00
191_F	195_G	1.638	1.00
329_N	333_R	1.632	1.00
25_L	29_F	1.627	1.00
356_D	414_G	1.600	1.00
210_A	214_Q	1.587	1.00
202_A	205_I	1.571	1.00
188_G	192_E	1.565	1.00
352_L	419_F	1.559	1.00
326_N	394_V	1.548	1.00
283_P	287_S	1.544	1.00
235_E	249_N	1.534	1.00
335_C	339_V	1.531	1.00
316_D	319_L	1.529	1.00
340_E	357_D	1.473	1.00
174_F	202_A	1.461	1.00
153_V	157_M	1.459	1.00
168_E	193_R	1.453	1.00
365_N	376_L	1.445	1.00
230_L	252_I	1.441	1.00
199_N	202_A	1.441	1.00
206_N	209_I	1.441	1.00
370_F	407_C	1.432	1.00
212_K	216_I	1.427	1.00
319_L	322_R	1.420	1.00
195_G	199_N	1.413	1.00
222_E	322_R	1.411	1.00
323_V	419_F	1.409	1.00
398_A	405_V	1.401	1.00
409_T	412_L	1.397	1.00
366_R	370_F	1.397	1.00
334_Y	375_R	1.382	1.00
230_L	248_L	1.368	1.00
171_A	174_F	1.360	1.00
241_S	244_E	1.359	1.00
283_P	343_L	1.358	1.00
319_L	397_I	1.343	1.00
409_T	413_G	1.336	1.00
209_I	212_K	1.327	1.00
229_R	233_R	1.319	1.00
337_S	357_D	1.313	1.00
371_E	374_V	1.313	1.00
182_R	203_D	1.311	1.00
288_T	317_M	1.307	1.00
370_F	417_F	1.305	1.00
168_E	172_Q	1.304	1.00
249_N	253_S	1.301	1.00
317_M	321_E	1.299	1.00
281_D	312_Y	1.297	1.00
362_A	411_E	1.290	1.00
208_L	212_K	1.290	1.00
173_R	181_E	1.273	1.00
396_S	399_L	1.271	1.00
294_Q	298_P	1.263	1.00
218_G	372_P	1.247	1.00
229_R	251_D	1.234	1.00
292_D	321_E	1.233	1.00
231_R	249_N	1.227	1.00
215_L	219_I	1.226	1.00
403_G	421_W	1.212	1.00
275_L	316_D	1.198	1.00
234_L	252_I	1.195	1.00
283_P	308_V	1.190	1.00
349_R	404_T	1.186	1.00
290_L	306_T	1.184	1.00
207_A	211_S	1.173	1.00
198_F	201_M	1.169	1.00
407_C	415_A	1.162	1.00
319_L	400_A	1.154	1.00
369_I	407_C	1.142	1.00
285_W	289_H	1.141	1.00
355_E	410_S	1.138	1.00
157_M	161_W	1.138	1.00
136_L	140_A	1.136	1.00
191_F	194_L	1.132	1.00
370_F	395_H	1.123	1.00
257_A	318_R	1.121	1.00
206_N	210_A	1.120	1.00
178_H	181_E	1.113	1.00
171_A	198_F	1.108	1.00
308_V	343_L	1.095	1.00
287_S	306_T	1.094	1.00
233_R	247_A	1.093	1.00
246_Q	250_R	1.092	1.00
26_V	30_T	1.090	1.00
286_L	343_L	1.088	1.00
260_E	264_T	1.081	1.00
375_R	384_T	1.071	1.00
187_E	195_G	1.069	1.00
32_E	36_K	1.068	1.00
296_V	299_D	1.056	1.00
80_E	86_H	1.055	1.00
224_R	260_E	1.049	1.00
356_D	415_A	1.048	1.00
263_L	266_A	1.044	1.00
289_H	325_D	1.040	1.00
331_A	339_V	1.039	1.00
229_R	232_Y	1.039	1.00
363_P	409_T	1.033	1.00
240_L	245_S	1.033	1.00
172_Q	193_R	1.029	1.00
277_L	401_M	1.024	1.00
327_L	417_F	1.024	1.00
242_A	245_S	1.021	1.00
170_A	183_I	1.017	1.00
182_R	202_A	1.009	1.00
320_M	401_M	1.005	1.00
165_L	168_E	1.000	1.00
192_E	195_G	0.999	1.00
327_L	405_V	0.996	1.00
171_A	197_A	0.994	1.00
222_E	326_N	0.994	1.00
308_V	311_H	0.993	1.00
324_L	354_V	0.984	1.00
251_D	254_Q	0.982	1.00
7_Q	189_S	0.974	1.00
171_A	175_G	0.973	1.00
326_N	329_N	0.972	1.00
40_D	44_N	0.966	1.00
158_R	162_Q	0.966	1.00
182_R	199_N	0.962	1.00
168_E	197_A	0.957	1.00
184_H	199_N	0.957	1.00
240_L	243_A	0.956	1.00
200_Q	204_N	0.956	1.00
289_H	293_I	0.954	1.00
361_I	366_R	0.949	1.00
24_G	28_K	0.947	1.00
231_R	235_E	0.943	1.00
389_L	393_I	0.943	1.00
192_E	196_V	0.941	1.00
46_S	49_L	0.940	1.00
197_A	200_Q	0.939	1.00
398_A	421_W	0.938	1.00
285_W	315_L	0.935	1.00
221_H	326_N	0.934	1.00
369_I	417_F	0.933	1.00
132_H	136_L	0.932	1.00
309_Q	344_L	0.928	1.00
327_L	394_V	0.925	1.00
280_P	285_W	0.916	1.00
124_P	128_L	0.913	1.00
106_Q	110_L	0.912	1.00
214_Q	372_P	0.910	1.00
116_S	121_A	0.908	1.00
115_R	118_Y	0.907	1.00
247_A	251_D	0.906	1.00
150_A	154_F	0.906	1.00
114_P	118_Y	0.906	1.00
284_L	288_T	0.906	1.00
261_E	319_L	0.905	1.00
28_K	135_R	0.904	1.00
346_S	420_S	0.902	1.00
185_F	196_V	0.900	1.00
346_S	349_R	0.900	1.00
151_F	155_I	0.899	1.00
44_N	48_Y	0.899	1.00
160_H	163_D	0.899	1.00
187_E	191_F	0.897	1.00
174_F	201_M	0.893	1.00
289_H	321_E	0.890	1.00
361_I	367_E	0.889	1.00
325_D	329_N	0.889	1.00
51_R	55_R	0.887	1.00
236_M	239_N	0.883	1.00
360_G	415_A	0.882	1.00
334_Y	359_P	0.878	1.00
202_A	206_N	0.876	1.00
292_D	325_D	0.875	1.00
302_V	335_C	0.875	1.00
290_L	294_Q	0.871	1.00
117_H	121_A	0.871	1.00
170_A	181_E	0.868	1.00
372_P	396_S	0.867	1.00
324_L	328_L	0.866	1.00
327_L	419_F	0.861	1.00
361_I	407_C	0.860	1.00
39_L	43_M	0.860	1.00
47_L	51_R	0.857	1.00
29_F	32_E	0.857	1.00
293_I	328_L	0.855	1.00
63_G	67_K	0.853	1.00
323_V	401_M	0.853	1.00
286_L	324_L	0.850	1.00
222_E	226_P	0.849	1.00
248_L	252_I	0.847	1.00
250_R	288_T	0.845	1.00
198_F	202_A	0.843	1.00
289_H	328_L	0.842	1.00
43_M	47_L	0.842	1.00
287_S	291_A	0.840	1.00
252_I	256_E	0.839	1.00
253_S	256_E	0.837	1.00
38_S	42_L	0.828	1.00
257_A	261_E	0.827	1.00
296_V	329_N	0.821	1.00
341_T	354_V	0.820	1.00
36_K	40_D	0.818	1.00
135_R	139_I	0.817	1.00
225_T	229_R	0.812	1.00
175_G	200_Q	0.811	1.00
282_L	352_L	0.808	1.00
233_R	251_D	0.807	1.00
228_V	232_Y	0.807	1.00
276_H	316_D	0.805	1.00
318_R	321_E	0.802	1.00
155_I	159_P	0.802	1.00
255_L	259_I	0.799	1.00
328_L	341_T	0.799	1.00
209_I	213_K	0.795	1.00
208_L	211_S	0.795	1.00
98_G	103_L	0.794	1.00
29_F	33_R	0.794	1.00
293_I	329_N	0.793	1.00
194_L	198_F	0.792	1.00
363_P	367_E	0.791	1.00
106_Q	112_R	0.791	1.00
168_E	171_A	0.790	1.00
163_D	167_L	0.786	1.00
42_L	45_S	0.786	1.00
223_L	255_L	0.785	1.00
282_L	350_A	0.785	1.00
396_S	400_A	0.785	1.00
297_T	339_V	0.780	1.00
275_L	319_L	0.780	1.00
321_E	325_D	0.779	1.00
362_A	376_L	0.777	1.00
107_Y	110_L	0.776	1.00
81_P	87_L	0.775	1.00
302_V	306_T	0.774	1.00
154_F	158_R	0.774	1.00
78_R	86_H	0.771	1.00
277_L	315_L	0.769	1.00
157_M	160_H	0.768	1.00
403_G	419_F	0.768	1.00
395_H	404_T	0.767	1.00
181_E	185_F	0.766	1.00
136_L	139_I	0.766	1.00
283_P	310_G	0.766	1.00
183_I	195_G	0.765	1.00
188_G	191_F	0.765	1.00
159_P	162_Q	0.763	1.00
394_V	398_A	0.762	1.00
110_L	113_I	0.761	1.00
131_L	135_R	0.760	1.00
169_A	173_R	0.759	1.00
193_R	196_V	0.756	1.00
171_A	194_L	0.754	1.00
261_E	322_R	0.753	1.00
15_C	19_M	0.753	1.00
114_P	117_H	0.752	1.00
277_L	402_G	0.752	1.00
216_I	219_I	0.747	1.00
43_M	46_S	0.747	1.00
227_L	259_I	0.747	1.00
35_G	38_S	0.746	1.00
240_L	244_E	0.746	1.00
53_E	56_E	0.745	1.00
375_R	386_G	0.744	1.00
361_I	409_T	0.741	1.00
48_Y	51_R	0.738	1.00
105_D	108_T	0.737	1.00
265_Y	392_A	0.735	1.00
296_V	300_K	0.734	1.00
37_Q	40_D	0.733	1.00
264_T	322_R	0.732	1.00
118_Y	122_V	0.731	1.00
171_A	201_M	0.731	1.00
73_L	76_D	0.729	1.00
39_L	42_L	0.728	1.00
183_I	199_N	0.727	1.00
167_L	171_A	0.724	1.00
356_D	359_P	0.722	1.00
355_E	412_L	0.721	1.00
40_D	107_Y	0.721	1.00
322_R	397_I	0.717	1.00
333_R	384_T	0.715	1.00
210_A	213_K	0.713	1.00
21_L	25_L	0.713	1.00
406_N	419_F	0.712	1.00
221_H	225_T	0.711	1.00
38_S	41_D	0.710	1.00
363_P	410_S	0.710	1.00
81_P	84_K	0.707	1.00
319_L	323_V	0.706	1.00
124_P	127_Y	0.706	1.00
222_E	393_I	0.706	1.00
366_R	417_F	0.705	1.00
195_G	198_F	0.704	1.00
311_H	345_L	0.704	1.00
280_P	317_M	0.703	1.00
224_R	256_E	0.702	1.00
42_L	46_S	0.701	1.00
233_R	248_L	0.700	1.00
108_T	112_R	0.698	1.00
287_S	290_L	0.694	1.00
47_L	50_M	0.693	1.00
175_G	204_N	0.692	1.00
247_A	250_R	0.690	1.00
345_L	350_A	0.689	1.00
366_R	408_D	0.688	1.00
264_T	319_L	0.687	1.00
361_I	417_F	0.687	1.00
172_Q	197_A	0.687	1.00
219_I	262_L	0.686	1.00
52_S	56_E	0.685	1.00
34_A	38_S	0.683	1.00
196_V	200_Q	0.683	1.00
228_V	231_R	0.681	1.00
246_Q	249_N	0.679	1.00
371_E	395_H	0.678	1.00
132_H	135_R	0.677	1.00
218_G	222_E	0.677	1.00
327_L	398_A	0.675	1.00
303_R	306_T	0.674	1.00
393_I	397_I	0.673	1.00
286_L	341_T	0.673	1.00
107_Y	112_R	0.673	1.00
36_K	39_L	0.672	1.00
163_D	189_S	0.672	1.00
189_S	193_R	0.671	1.00
331_A	354_V	0.671	1.00
291_A	294_Q	0.671	1.00
127_Y	130_Y	0.671	1.00
164_M	194_L	0.669	1.00
297_T	304_I	0.669	1.00
162_Q	166_K	0.667	1.00
343_L	352_L	0.665	1.00
254_Q	321_E	0.665	1.00
165_L	169_A	0.665	1.00
133_Q	137_L	0.664	1.00
359_P	384_T	0.662	1.00
50_M	53_E	0.661	1.00
185_F	195_G	0.659	1.00
193_R	197_A	0.658	1.00
72_N	75_F	0.658	1.00
215_L	222_E	0.658	1.00
328_L	339_V	0.658	1.00
201_M	204_N	0.657	1.00
229_R	247_A	0.656	1.00
213_K	269_D	0.655	1.00
280_P	314_A	0.653	1.00
275_L	400_A	0.653	1.00
133_Q	136_L	0.652	1.00
41_D	44_N	0.651	1.00
343_L	350_A	0.651	1.00
139_I	143_A	0.650	1.00
123_G	127_Y	0.648	1.00
295_A	299_D	0.648	1.00
269_D	372_P	0.648	1.00
109_F	113_I	0.647	1.00
40_D	43_M	0.647	1.00
293_I	332_L	0.646	1.00
353_I	408_D	0.645	1.00
204_N	207_A	0.645	1.00
170_A	173_R	0.644	1.00
205_I	208_L	0.643	1.00
123_G	126_P	0.642	1.00
207_A	210_A	0.641	1.00
28_K	32_E	0.641	1.00
263_L	267_R	0.641	1.00
394_V	397_I	0.640	1.00
223_L	226_P	0.640	1.00
181_E	184_H	0.640	1.00
282_L	313_A	0.639	1.00
179_L	202_A	0.637	1.00
297_T	300_K	0.637	1.00
67_K	71_L	0.636	1.00
298_P	301_T	0.635	1.00
365_N	378_P	0.634	1.00
290_L	304_I	0.633	1.00
45_S	48_Y	0.630	1.00
194_L	197_A	0.630	1.00
128_L	132_H	0.627	1.00
302_V	332_L	0.627	1.00
25_L	28_K	0.625	1.00
291_A	295_A	0.624	1.00
307_L	344_L	0.624	1.00
84_K	88_D	0.624	1.00
33_R	37_Q	0.623	1.00
188_G	195_G	0.622	1.00
65_T	68_E	0.620	1.00
285_W	320_M	0.619	1.00
211_S	214_Q	0.619	1.00
284_L	287_S	0.619	1.00
403_G	422_P	0.618	1.00
107_Y	111_Q	0.616	1.00
405_V	417_F	0.614	1.00
295_A	298_P	0.614	1.00
33_R	36_K	0.614	1.00
164_M	191_F	0.614	1.00
360_G	414_G	0.613	1.00
333_R	386_G	0.609	1.00
166_K	169_A	0.606	1.00
159_P	163_D	0.606	1.00
273_N	319_L	0.605	1.00
265_Y	396_S	0.605	1.00
30_T	33_R	0.604	1.00
309_Q	342_S	0.604	1.00
328_L	332_L	0.603	1.00
22_L	26_V	0.601	1.00
149_L	153_V	0.601	1.00
172_Q	176_D	0.600	1.00
112_R	121_A	0.599	1.00
48_Y	52_S	0.598	1.00
287_S	308_V	0.597	1.00
64_K	67_K	0.596	1.00
366_R	415_A	0.596	1.00
288_T	292_D	0.595	1.00
14_V	21_L	0.594	1.00
216_I	220_A	0.593	1.00
349_R	422_P	0.593	1.00
414_G	417_F	0.592	1.00
104_D	108_T	0.591	1.00
262_L	373_F	0.590	1.00
108_T	111_Q	0.590	1.00
167_L	198_F	0.589	1.00
78_R	84_K	0.587	1.00
127_Y	131_L	0.586	1.00
194_L	199_N	0.585	1.00
169_A	172_Q	0.585	1.00
251_D	292_D	0.585	1.00
289_H	292_D	0.582	1.00
106_Q	109_F	0.581	1.00
367_E	371_E	0.580	1.00
297_T	301_T	0.580	1.00
265_Y	372_P	0.580	1.00
339_V	354_V	0.580	1.00
232_Y	252_I	0.580	1.00
309_Q	343_L	0.579	1.00
14_V	17_L	0.579	1.00
12_L	153_V	0.578	1.00
369_I	374_V	0.578	1.00
37_Q	41_D	0.577	1.00
369_I	392_A	0.577	1.00
379_S	385_G	0.576	1.00
197_A	201_M	0.576	1.00
67_K	70_D	0.575	1.00
302_V	357_D	0.575	1.00
16_F	19_M	0.573	1.00
351_T	406_N	0.573	1.00
54_L	58_P	0.572	1.00
189_S	195_G	0.571	1.00
233_R	252_I	0.570	1.00
225_T	263_L	0.569	1.00
336_H	357_D	0.569	1.00
284_L	317_M	0.567	1.00
137_L	140_A	0.567	1.00
137_L	141_L	0.567	1.00
203_D	207_A	0.566	1.00
78_R	81_P	0.566	1.00
375_R	385_G	0.566	1.00
290_L	341_T	0.564	1.00
86_H	89_D	0.563	1.00
392_A	396_S	0.561	1.00
195_G	202_A	0.559	1.00
190_S	194_L	0.558	1.00
41_D	45_S	0.558	1.00
187_E	190_S	0.558	1.00
11_L	15_C	0.558	1.00
162_Q	165_L	0.557	1.00
319_L	401_M	0.555	1.00
172_Q	175_G	0.555	1.00
255_L	263_L	0.554	1.00
297_T	302_V	0.553	1.00
163_D	187_E	0.552	1.00
214_Q	396_S	0.549	1.00
264_T	267_R	0.549	1.00
30_T	34_A	0.547	1.00
138_D	141_L	0.545	1.00
249_N	252_I	0.545	1.00
166_K	170_A	0.544	1.00
224_R	255_L	0.542	1.00
275_L	401_M	0.540	1.00
362_A	366_R	0.539	1.00
143_A	147_I	0.539	1.00
253_S	257_A	0.538	1.00
322_R	325_D	0.538	1.00
313_A	350_A	0.538	1.00
280_P	320_M	0.536	1.00
333_R	377_D	0.536	1.00
223_L	227_L	0.536	1.00
345_L	349_R	0.534	1.00
164_M	168_E	0.534	1.00
285_W	321_E	0.532	1.00
340_E	343_L	0.531	1.00
222_E	225_T	0.531	1.00
13_F	16_F	0.530	1.00
6_I	10_L	0.530	1.00
45_S	49_L	0.529	1.00
163_D	166_K	0.528	1.00
114_P	121_A	0.528	1.00
187_E	194_L	0.528	1.00
225_T	232_Y	0.527	1.00
166_K	184_H	0.526	1.00
213_K	216_I	0.525	1.00
78_R	89_D	0.524	1.00
194_L	201_M	0.521	1.00
222_E	258_L	0.520	1.00
12_L	15_C	0.518	1.00
49_L	53_E	0.518	1.00
215_L	218_G	0.518	1.00
52_S	55_R	0.517	1.00
241_S	245_S	0.517	1.00
163_D	171_A	0.516	1.00
180_N	202_A	0.516	1.00
217_D	220_A	0.515	1.00
10_L	13_F	0.512	1.00
213_K	217_D	0.512	1.00
167_L	195_G	0.512	1.00
223_L	259_I	0.512	1.00
330_N	390_G	0.511	1.00
131_L	134_M	0.511	1.00
300_K	335_C	0.509	1.00
53_E	57_I	0.509	1.00
232_Y	236_M	0.508	1.00
116_S	119_V	0.507	1.00
220_A	225_T	0.506	1.00
117_H	120_L	0.502	1.00
199_N	203_D	0.502	1.00
359_P	415_A	0.501	1.00
331_A	335_C	0.501	1.00
213_K	218_G	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4i5sA	2	0.6097	100	0.354	Contact Map
4bixA	2	0.5196	100	0.371	Contact Map
4ctiA	2	0.5266	100	0.389	Contact Map
4q20A	2	0.515	100	0.464	Contact Map
4gczA	2	0.8106	100	0.479	Contact Map
4mpcA	2	0.6813	100	0.483	Contact Map
2c2aA	2	0.5173	100	0.487	Contact Map
3jz3A	2	0.3603	100	0.487	Contact Map
3a0rA	2	0.7367	100	0.492	Contact Map
3d36A	2	0.4919	100	0.495	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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