CYSI - ECOLI - GREMLIN Contacts

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CYSI - Sulfite reductase [NADPH] hemoprotein beta-component

UniProt:	P17846	Sequences: MSEKHPGPLVVEGKLTDAERMKHESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKFAGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPARPLKTGLLEIAKIHKGDFRITANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGNRIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDLWD	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10190
Length:	570 (493)
Sequences:	2505 (1319)
Seq/√Len:	59.4

ECOLI - CYSI
BACSU - CYSI
SULSO - Q97UT4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
104_G	377_T	4.871	1.00
318_T	321_A	4.580	1.00
322_E	325_R	4.292	1.00
101_K	105_E	4.107	1.00
248_G	276_Y	3.691	1.00
281_H	329_I	3.605	1.00
97_Q	384_K	3.585	1.00
546_E	554_R	3.501	1.00
321_A	325_R	3.478	1.00
314_V	318_T	3.308	1.00
278_P	281_H	3.036	1.00
105_E	136_M	3.023	1.00
298_N	304_N	3.009	1.00
404_P	407_E	2.982	1.00
235_M	289_V	2.936	1.00
237_F	286_A	2.871	1.00
477_T	484_G	2.828	1.00
368_L	371_P	2.779	1.00
379_L	398_L	2.776	1.00
237_F	251_L	2.697	1.00
389_D	402_G	2.677	1.00
317_E	320_K	2.617	1.00
126_L	129_N	2.610	1.00
403_V	411_I	2.536	1.00
114_L	398_L	2.520	1.00
216_F	290_V	2.508	1.00
537_R	541_E	2.433	1.00
98_A	136_M	2.430	1.00
114_L	392_I	2.409	1.00
523_T	526_E	2.395	1.00
97_Q	381_E	2.347	1.00
106_N	132_P	2.315	1.00
363_E	369_D	2.304	1.00
242_E	245_K	2.298	1.00
160_N	227_D	2.283	1.00
363_E	371_P	2.280	1.00
350_K	405_E	2.206	1.00
192_W	220_V	2.200	1.00
318_T	322_E	2.196	1.00
34_E	38_D	2.189	1.00
220_V	237_F	2.184	1.00
503_L	522_I	2.161	1.00
390_F	398_L	2.151	1.00
84_C	122_F	2.139	1.00
319_F	323_V	2.138	1.00
356_W	405_E	2.135	1.00
513_R	553_V	2.135	1.00
382_I	414_I	2.130	1.00
547_G	550_D	2.130	1.00
235_M	286_A	2.124	1.00
366_R	369_D	2.120	1.00
242_E	246_L	2.100	1.00
101_K	377_T	2.076	1.00
155_V	192_W	2.040	1.00
292_T	323_V	2.027	1.00
288_A	323_V	2.020	1.00
522_I	530_S	2.004	1.00
219_T	228_I	1.996	1.00
106_N	136_M	1.991	1.00
431_S	451_L	1.980	1.00
407_E	410_K	1.973	1.00
385_I	414_I	1.956	1.00
366_R	371_P	1.885	1.00
360_L	415_A	1.876	1.00
409_A	413_K	1.852	1.00
363_E	368_L	1.841	1.00
192_W	286_A	1.840	1.00
349_V	357_H	1.837	1.00
232_A	488_L	1.809	0.99
188_Y	249_F	1.808	0.99
250_N	270_T	1.781	0.99
304_N	313_R	1.770	0.99
132_P	136_M	1.751	0.99
532_D	536_G	1.739	0.99
160_N	223_P	1.710	0.99
252_L	270_T	1.709	0.99
497_A	500_R	1.707	0.99
110_G	370_Y	1.707	0.99
99_I	122_F	1.706	0.99
457_N	529_A	1.706	0.99
219_T	233_N	1.703	0.99
112_I	376_K	1.702	0.99
272_S	277_L	1.687	0.99
98_A	101_K	1.683	0.99
156_L	394_A	1.683	0.99
358_L	411_I	1.678	0.99
322_E	326_R	1.668	0.99
98_A	139_S	1.665	0.99
179_E	350_K	1.642	0.99
42_G	78_H	1.637	0.99
266_T	269_R	1.637	0.99
98_A	140_V	1.632	0.99
307_T	319_F	1.618	0.99
281_H	284_A	1.599	0.99
237_F	249_F	1.593	0.99
464_K	532_D	1.588	0.99
135_Q	139_S	1.585	0.99
381_E	384_K	1.583	0.99
450_F	524_E	1.582	0.99
296_W	322_E	1.581	0.99
378_G	418_S	1.577	0.99
251_L	285_V	1.557	0.98
363_E	366_R	1.548	0.98
393_T	399_I	1.539	0.98
284_A	327_A	1.535	0.98
382_I	411_I	1.530	0.98
314_V	322_E	1.528	0.98
266_T	312_E	1.501	0.98
104_G	376_K	1.493	0.98
183_P	279_L	1.492	0.98
93_T	384_K	1.492	0.98
101_K	136_M	1.491	0.98
472_I	535_I	1.489	0.98
240_I	276_Y	1.472	0.98
489_A	507_G	1.462	0.98
428_R	459_D	1.460	0.98
237_F	282_T	1.454	0.98
58_Y	61_D	1.435	0.97
102_F	133_V	1.425	0.97
298_N	313_R	1.424	0.97
385_I	407_E	1.412	0.97
350_K	354_D	1.406	0.97
541_E	555_A	1.394	0.97
363_E	370_Y	1.386	0.97
461_L	532_D	1.383	0.97
223_P	227_D	1.378	0.97
231_H	252_L	1.373	0.97
253_V	319_F	1.369	0.97
386_H	414_I	1.361	0.96
155_V	189_A	1.357	0.96
114_L	362_I	1.344	0.96
324_E	330_K	1.326	0.96
409_A	412_E	1.323	0.96
32_I	35_D	1.314	0.96
508_N	512_T	1.313	0.96
96_W	376_K	1.310	0.95
67_A	71_E	1.309	0.95
333_P	336_P	1.306	0.95
35_D	48_N	1.303	0.95
93_T	383_A	1.297	0.95
188_Y	279_L	1.287	0.95
68_E	71_E	1.286	0.95
69_R	74_L	1.286	0.95
425_T	459_D	1.283	0.95
112_I	122_F	1.282	0.95
281_H	332_E	1.275	0.95
467_V	539_A	1.275	0.95
86_L	91_I	1.274	0.95
102_F	136_M	1.270	0.95
542_R	554_R	1.267	0.95
311_L	314_V	1.264	0.95
508_N	553_V	1.260	0.94
249_F	282_T	1.256	0.94
246_L	249_F	1.253	0.94
269_R	272_S	1.249	0.94
270_T	273_E	1.244	0.94
531_L	535_I	1.243	0.94
102_F	142_L	1.243	0.94
36_L	39_G	1.240	0.94
46_G	132_P	1.235	0.94
355_N	404_P	1.231	0.94
84_C	142_L	1.215	0.93
96_W	390_F	1.213	0.93
31_T	35_D	1.210	0.93
350_K	356_W	1.205	0.93
288_A	292_T	1.200	0.93
355_N	405_E	1.187	0.92
35_D	39_G	1.184	0.92
276_Y	279_L	1.179	0.92
456_D	460_N	1.177	0.92
165_Q	402_G	1.171	0.92
387_K	402_G	1.169	0.92
410_K	414_I	1.165	0.92
504_H	517_M	1.164	0.92
253_V	323_V	1.160	0.92
287_E	291_T	1.160	0.92
324_E	328_G	1.159	0.92
101_K	104_G	1.158	0.91
281_H	327_A	1.156	0.91
92_T	95_Q	1.151	0.91
104_G	369_D	1.148	0.91
33_A	37_N	1.146	0.91
505_L	534_L	1.146	0.91
230_L	238_V	1.144	0.91
316_V	320_K	1.144	0.91
526_E	529_A	1.141	0.91
382_I	386_H	1.141	0.91
504_H	515_P	1.137	0.91
314_V	319_F	1.132	0.91
129_N	132_P	1.131	0.90
89_G	154_N	1.129	0.90
71_E	130_V	1.128	0.90
315_G	318_T	1.124	0.90
278_P	332_E	1.122	0.90
453_S	456_D	1.122	0.90
408_K	412_E	1.120	0.90
392_I	398_L	1.115	0.90
384_K	388_G	1.113	0.90
457_N	532_D	1.109	0.90
364_N	369_D	1.109	0.90
454_F	524_E	1.108	0.90
269_R	312_E	1.105	0.89
134_H	144_A	1.101	0.89
183_P	247_V	1.095	0.89
104_G	110_G	1.094	0.89
289_V	319_F	1.093	0.89
450_F	476_V	1.089	0.89
285_V	327_A	1.089	0.89
204_E	208_G	1.082	0.88
537_R	555_A	1.080	0.88
94_K	354_D	1.076	0.88
100_D	377_T	1.075	0.88
217_K	256_G	1.073	0.88
542_R	546_E	1.072	0.88
414_I	418_S	1.069	0.88
295_D	326_R	1.069	0.88
400_I	411_I	1.068	0.88
122_F	133_V	1.061	0.87
267_Y	312_E	1.061	0.87
537_R	551_F	1.059	0.87
291_T	326_R	1.057	0.87
148_A	308_K	1.056	0.87
219_T	230_L	1.050	0.87
61_D	66_R	1.047	0.87
445_A	501_Y	1.044	0.87
353_D	402_G	1.037	0.86
50_L	54_F	1.032	0.86
496_K	500_R	1.032	0.86
496_K	499_G	1.028	0.86
482_G	486_A	1.028	0.86
414_I	417_E	1.028	0.86
444_M	496_K	1.024	0.86
269_R	316_V	1.023	0.85
311_L	316_V	1.022	0.85
161_P	393_T	1.021	0.85
49_F	52_I	1.019	0.85
379_L	390_F	1.017	0.85
103_A	122_F	1.015	0.85
482_G	487_M	1.015	0.85
442_L	481_N	1.014	0.85
34_E	141_G	1.004	0.84
37_N	40_L	1.003	0.84
413_K	417_E	1.002	0.84
348_W	408_K	1.002	0.84
52_I	80_M	1.001	0.84
508_N	513_R	0.998	0.84
86_L	119_T	0.997	0.84
149_N	256_G	0.995	0.84
104_G	370_Y	0.995	0.84
446_E	449_R	0.994	0.84
47_D	50_L	0.994	0.84
67_A	70_A	0.993	0.84
367_I	379_L	0.992	0.84
162_Y	357_H	0.992	0.84
381_E	385_I	0.988	0.83
457_N	528_L	0.986	0.83
87_P	154_N	0.985	0.83
156_L	233_N	0.984	0.83
551_F	555_A	0.982	0.83
157_C	185_T	0.980	0.83
125_I	133_V	0.980	0.83
84_C	99_I	0.979	0.83
242_E	247_V	0.978	0.83
241_A	244_G	0.978	0.83
35_D	38_D	0.976	0.83
348_W	412_E	0.976	0.83
161_P	359_T	0.975	0.83
93_T	400_I	0.974	0.83
238_V	250_N	0.974	0.83
525_P	532_D	0.972	0.82
490_E	549_G	0.967	0.82
150_D	302_R	0.965	0.82
52_I	57_M	0.964	0.82
379_L	400_I	0.963	0.82
125_I	130_V	0.959	0.82
379_L	418_S	0.958	0.81
178_S	222_I	0.956	0.81
556_G	559_R	0.956	0.81
133_V	141_G	0.955	0.81
411_I	414_I	0.950	0.81
522_I	527_I	0.950	0.81
364_N	432_M	0.942	0.80
403_V	408_K	0.942	0.80
232_A	514_I	0.942	0.80
149_N	217_K	0.941	0.80
296_W	314_V	0.941	0.80
114_L	120_F	0.940	0.80
189_A	220_V	0.940	0.80
364_N	368_L	0.938	0.80
238_V	252_L	0.936	0.80
369_D	377_T	0.935	0.80
94_K	98_A	0.935	0.80
543_E	550_D	0.933	0.80
298_N	301_D	0.932	0.80
123_H	217_K	0.931	0.80
94_K	140_V	0.923	0.79
412_E	416_K	0.918	0.79
343_G	408_K	0.914	0.78
112_I	120_F	0.909	0.78
241_A	245_K	0.909	0.78
63_R	302_R	0.907	0.78
281_H	331_F	0.906	0.78
516_R	553_V	0.904	0.78
204_E	287_E	0.897	0.77
349_V	359_T	0.896	0.77
378_G	381_E	0.894	0.77
511_G	547_G	0.893	0.77
36_L	40_L	0.889	0.76
499_G	517_M	0.887	0.76
348_W	358_L	0.886	0.76
190_E	196_E	0.885	0.76
85_R	199_A	0.883	0.76
333_P	337_Y	0.882	0.76
387_K	407_E	0.881	0.76
470_E	538_W	0.879	0.76
110_G	501_Y	0.878	0.75
75_E	80_M	0.876	0.75
381_E	417_E	0.872	0.75
359_T	393_T	0.871	0.75
35_D	43_G	0.869	0.75
243_N	246_L	0.867	0.75
406_S	413_K	0.865	0.74
358_L	408_K	0.863	0.74
204_E	209_Q	0.862	0.74
344_D	429_E	0.857	0.74
378_G	420_L	0.857	0.74
457_N	461_L	0.856	0.74
317_E	541_E	0.853	0.73
44_F	59_Q	0.853	0.73
68_E	75_E	0.848	0.73
327_A	331_F	0.847	0.73
277_L	285_V	0.847	0.73
251_L	289_V	0.845	0.73
32_I	40_L	0.839	0.72
163_E	186_R	0.838	0.72
123_H	256_G	0.834	0.72
273_E	334_I	0.828	0.71
524_E	528_L	0.827	0.71
241_A	247_V	0.827	0.71
377_T	381_E	0.824	0.71
336_P	339_F	0.824	0.71
351_G	355_N	0.823	0.71
132_P	135_Q	0.823	0.71
395_N	488_L	0.822	0.71
183_P	239_A	0.821	0.70
90_V	389_D	0.821	0.70
536_G	540_K	0.821	0.70
415_A	420_L	0.820	0.70
156_L	219_T	0.816	0.70
472_I	491_V	0.814	0.70
123_H	149_N	0.813	0.70
439_T	447_A	0.813	0.70
505_L	518_Y	0.812	0.70
40_L	43_G	0.812	0.70
511_G	550_D	0.811	0.69
277_L	282_T	0.810	0.69
503_L	527_I	0.809	0.69
97_Q	380_L	0.804	0.69
535_I	538_W	0.804	0.69
265_K	301_D	0.804	0.69
146_A	151_M	0.803	0.69
163_E	181_L	0.802	0.69
386_H	400_I	0.801	0.69
513_R	550_D	0.800	0.68
109_Y	124_G	0.796	0.68
162_Y	359_T	0.796	0.68
58_Y	148_A	0.794	0.68
505_L	552_T	0.793	0.68
82_L	133_V	0.792	0.68
68_E	210_T	0.791	0.68
94_K	384_K	0.790	0.67
164_S	181_L	0.789	0.67
141_G	189_A	0.785	0.67
416_K	421_M	0.785	0.67
100_D	376_K	0.781	0.67
218_T	286_A	0.777	0.66
93_T	388_G	0.773	0.66
84_C	119_T	0.773	0.66
163_E	184_R	0.771	0.66
100_D	380_L	0.771	0.66
351_G	357_H	0.769	0.65
89_G	95_Q	0.769	0.65
289_V	307_T	0.767	0.65
461_L	465_H	0.766	0.65
356_W	408_K	0.765	0.65
481_N	495_G	0.761	0.65
386_H	410_K	0.761	0.65
242_E	248_G	0.759	0.64
113_R	366_R	0.757	0.64
366_R	370_Y	0.757	0.64
71_E	74_L	0.752	0.64
214_R	299_R	0.751	0.64
450_F	527_I	0.748	0.63
183_P	188_Y	0.748	0.63
311_L	319_F	0.745	0.63
34_E	37_N	0.744	0.63
136_M	139_S	0.743	0.63
281_H	336_P	0.741	0.62
267_Y	514_I	0.741	0.62
106_N	491_V	0.740	0.62
332_E	336_P	0.740	0.62
301_D	304_N	0.738	0.62
476_V	493_L	0.737	0.62
458_I	461_L	0.736	0.62
389_D	401_A	0.736	0.62
35_D	52_I	0.733	0.62
240_I	250_N	0.733	0.62
386_H	407_E	0.733	0.62
180_H	225_Q	0.729	0.61
253_V	316_V	0.729	0.61
364_N	433_A	0.728	0.61
444_M	497_A	0.727	0.61
437_F	446_E	0.727	0.61
354_D	405_E	0.726	0.61
148_A	442_L	0.725	0.61
224_P	227_D	0.725	0.61
253_V	311_L	0.723	0.61
232_A	267_Y	0.722	0.60
318_T	323_V	0.722	0.60
360_L	379_L	0.719	0.60
513_R	516_R	0.719	0.60
251_L	315_G	0.717	0.60
110_G	369_D	0.716	0.60
71_E	133_V	0.716	0.60
356_W	402_G	0.714	0.60
148_A	217_K	0.713	0.60
486_A	492_G	0.713	0.60
364_N	371_P	0.712	0.59
465_H	536_G	0.711	0.59
330_K	336_P	0.710	0.59
547_G	551_F	0.710	0.59
363_E	367_I	0.708	0.59
346_I	471_H	0.707	0.59
279_L	331_F	0.707	0.59
116_N	258_S	0.706	0.59
244_G	247_V	0.706	0.59
65_I	68_E	0.705	0.59
371_P	420_L	0.705	0.59
296_W	325_R	0.704	0.59
452_P	456_D	0.703	0.58
344_D	348_W	0.701	0.58
321_A	406_S	0.701	0.58
157_C	220_V	0.701	0.58
111_S	439_T	0.700	0.58
515_P	519_K	0.700	0.58
235_M	251_L	0.698	0.58
236_N	258_S	0.696	0.58
44_F	80_M	0.695	0.58
88_G	157_C	0.695	0.58
553_V	558_I	0.695	0.58
317_E	321_A	0.694	0.57
91_I	390_F	0.694	0.57
226_N	230_L	0.693	0.57
428_R	474_M	0.692	0.57
416_K	423_A	0.691	0.57
450_F	501_Y	0.691	0.57
86_L	95_Q	0.689	0.57
115_T	503_L	0.689	0.57
534_L	557_I	0.688	0.57
235_M	283_L	0.688	0.57
253_V	320_K	0.685	0.56
385_I	406_S	0.684	0.56
101_K	106_N	0.683	0.56
500_R	523_T	0.682	0.56
358_L	403_V	0.680	0.56
187_A	191_I	0.680	0.56
214_R	492_G	0.678	0.56
249_F	400_I	0.675	0.55
493_L	503_L	0.674	0.55
288_A	327_A	0.672	0.55
32_I	38_D	0.671	0.55
378_G	414_I	0.670	0.55
450_F	453_S	0.670	0.55
103_A	376_K	0.670	0.55
558_I	561_V	0.668	0.55
300_T	313_R	0.668	0.55
95_Q	154_N	0.668	0.55
474_M	536_G	0.667	0.54
383_A	388_G	0.666	0.54
296_W	318_T	0.666	0.54
351_G	402_G	0.666	0.54
98_A	105_E	0.664	0.54
552_T	557_I	0.664	0.54
249_F	279_L	0.663	0.54
222_I	239_A	0.662	0.54
52_I	480_P	0.662	0.54
516_R	556_G	0.661	0.54
91_I	120_F	0.660	0.54
376_K	390_F	0.660	0.54
491_V	531_L	0.660	0.54
432_M	475_R	0.659	0.54
511_G	553_V	0.656	0.53
214_R	217_K	0.654	0.53
76_P	444_M	0.652	0.53
473_V	490_E	0.650	0.53
218_T	235_M	0.649	0.52
90_V	401_A	0.649	0.52
138_H	144_A	0.648	0.52
320_K	324_E	0.648	0.52
251_L	277_L	0.648	0.52
82_L	134_H	0.648	0.52
240_I	248_G	0.647	0.52
33_A	40_L	0.643	0.52
137_L	144_A	0.643	0.52
455_I	459_D	0.642	0.52
60_Q	63_R	0.641	0.52
324_E	331_F	0.641	0.52
58_Y	217_K	0.640	0.51
71_E	75_E	0.639	0.51
105_E	132_P	0.639	0.51
377_T	380_L	0.637	0.51
105_E	129_N	0.634	0.51
272_S	324_E	0.633	0.51
81_L	214_R	0.632	0.51
446_E	482_G	0.632	0.51
90_V	402_G	0.630	0.50
292_T	326_R	0.630	0.50
123_H	148_A	0.628	0.50
405_E	408_K	0.627	0.50
35_D	40_L	0.627	0.50
457_N	524_E	0.626	0.50
345_R	357_H	0.626	0.50
350_K	355_N	0.625	0.50
349_V	400_I	0.625	0.50
358_L	415_A	0.624	0.50
537_R	542_R	0.624	0.50
498_P	534_L	0.623	0.50
33_A	38_D	0.622	0.49
387_K	400_I	0.618	0.49
462_M	535_I	0.617	0.49
465_H	532_D	0.617	0.49
165_Q	358_L	0.617	0.49
66_R	70_A	0.615	0.49
220_V	239_A	0.614	0.49
333_P	338_E	0.614	0.49
116_N	154_N	0.614	0.49
94_K	388_G	0.613	0.48
123_H	147_T	0.612	0.48
161_P	399_I	0.612	0.48
272_S	320_K	0.611	0.48
32_I	447_A	0.610	0.48
154_N	389_D	0.610	0.48
80_M	480_P	0.610	0.48
47_D	51_L	0.609	0.48
419_G	422_N	0.609	0.48
246_L	278_P	0.608	0.48
280_E	333_P	0.608	0.48
239_A	247_V	0.605	0.48
534_L	560_P	0.605	0.48
130_V	302_R	0.604	0.47
183_P	222_I	0.603	0.47
114_L	367_I	0.603	0.47
356_W	404_P	0.601	0.47
147_T	217_K	0.601	0.47
129_N	133_V	0.600	0.47
362_I	397_N	0.597	0.47
332_E	335_R	0.596	0.47
233_N	447_A	0.596	0.47
162_Y	389_D	0.596	0.47
341_G	345_R	0.595	0.46
324_E	329_I	0.594	0.46
473_V	489_A	0.594	0.46
35_D	44_F	0.594	0.46
247_V	335_R	0.594	0.46
218_T	237_F	0.594	0.46
459_D	557_I	0.592	0.46
186_R	401_A	0.592	0.46
428_R	456_D	0.591	0.46
493_L	531_L	0.591	0.46
86_L	140_V	0.590	0.46
256_G	308_K	0.590	0.46
503_L	530_S	0.590	0.46
237_F	240_I	0.590	0.46
504_H	514_I	0.589	0.46
246_L	280_E	0.586	0.45
105_E	555_A	0.586	0.45
548_F	551_F	0.585	0.45
84_C	103_A	0.585	0.45
542_R	545_G	0.584	0.45
474_M	493_L	0.584	0.45
181_L	184_R	0.582	0.45
502_N	521_N	0.582	0.45
385_I	410_K	0.582	0.45
321_A	324_E	0.580	0.45
87_P	205_P	0.580	0.45
137_L	140_V	0.579	0.45
334_I	337_Y	0.577	0.44
454_F	474_M	0.576	0.44
236_N	268_A	0.575	0.44
508_N	549_G	0.573	0.44
33_A	39_G	0.573	0.44
134_H	138_H	0.573	0.44
237_F	253_V	0.572	0.44
102_F	137_L	0.572	0.44
389_D	403_V	0.572	0.44
449_R	452_P	0.572	0.44
435_V	448_E	0.570	0.44
108_I	122_F	0.570	0.44
69_R	75_E	0.569	0.44
530_S	533_E	0.568	0.43
32_I	84_C	0.568	0.43
65_I	69_R	0.568	0.43
385_I	544_A	0.568	0.43
57_M	91_I	0.567	0.43
253_V	289_V	0.567	0.43
318_T	325_R	0.564	0.43
85_R	143_D	0.562	0.43
248_G	313_R	0.561	0.43
92_T	550_D	0.561	0.43
103_A	112_I	0.561	0.43
395_N	475_R	0.560	0.43
307_T	310_T	0.559	0.42
52_I	447_A	0.559	0.42
254_G	311_L	0.558	0.42
509_R	547_G	0.556	0.42
477_T	486_A	0.556	0.42
383_A	390_F	0.555	0.42
220_V	304_N	0.554	0.42
115_T	446_E	0.554	0.42
155_V	286_A	0.553	0.42
125_I	144_A	0.553	0.42
114_L	156_L	0.552	0.42
505_L	528_L	0.552	0.42
297_G	305_A	0.551	0.42
105_E	245_K	0.551	0.42
325_R	350_K	0.550	0.41
451_L	476_V	0.550	0.41
34_E	39_G	0.550	0.41
293_Q	310_T	0.549	0.41
352_I	355_N	0.549	0.41
165_Q	353_D	0.549	0.41
245_K	278_P	0.546	0.41
227_D	345_R	0.546	0.41
400_I	403_V	0.546	0.41
447_A	552_T	0.545	0.41
126_L	133_V	0.544	0.41
256_G	514_I	0.544	0.41
352_I	386_H	0.544	0.41
245_K	355_N	0.543	0.41
67_A	492_G	0.542	0.41
260_E	308_K	0.541	0.41
400_I	544_A	0.540	0.40
288_A	326_R	0.540	0.40
330_K	333_P	0.539	0.40
39_G	44_F	0.539	0.40
86_L	390_F	0.539	0.40
462_M	467_V	0.537	0.40
427_Q	535_I	0.536	0.40
335_R	550_D	0.535	0.40
125_I	391_R	0.533	0.40
433_A	451_L	0.533	0.40
328_G	331_F	0.532	0.40
415_A	419_G	0.531	0.39
81_L	217_K	0.531	0.39
258_S	297_G	0.530	0.39
271_A	316_V	0.529	0.39
540_K	543_E	0.528	0.39
257_L	487_M	0.528	0.39
239_A	249_F	0.527	0.39
43_G	48_N	0.527	0.39
230_L	531_L	0.526	0.39
381_E	414_I	0.524	0.39
94_K	523_T	0.524	0.39
165_Q	401_A	0.524	0.39
555_A	558_I	0.524	0.39
360_L	378_G	0.523	0.39
55_H	62_D	0.523	0.39
81_L	255_G	0.522	0.38
247_V	279_L	0.522	0.38
165_Q	179_E	0.522	0.38
409_A	414_I	0.522	0.38
363_E	451_L	0.522	0.38
232_A	257_L	0.521	0.38
433_A	484_G	0.521	0.38
229_D	232_A	0.521	0.38
46_G	49_F	0.521	0.38
81_L	116_N	0.521	0.38
151_M	182_L	0.520	0.38
38_D	141_G	0.519	0.38
514_I	517_M	0.519	0.38
89_G	118_Q	0.516	0.38
252_L	271_A	0.516	0.38
221_V	230_L	0.516	0.38
497_A	522_I	0.516	0.38
391_R	420_L	0.516	0.38
125_I	322_E	0.516	0.38
232_A	509_R	0.516	0.38
557_I	561_V	0.515	0.38
213_P	255_G	0.515	0.38
476_V	528_L	0.515	0.38
245_K	276_Y	0.514	0.38
79_A	124_G	0.514	0.38
192_W	400_I	0.514	0.38
257_L	486_A	0.513	0.38
357_H	364_N	0.513	0.38
214_R	297_G	0.513	0.38
236_N	297_G	0.512	0.37
191_I	196_E	0.512	0.37
315_G	322_E	0.512	0.37
52_I	59_Q	0.511	0.37
289_V	482_G	0.511	0.37
36_L	43_G	0.511	0.37
209_Q	291_T	0.511	0.37
99_I	112_I	0.510	0.37
94_K	387_K	0.509	0.37
70_A	492_G	0.509	0.37
311_L	427_Q	0.509	0.37
378_G	382_I	0.509	0.37
269_R	420_L	0.509	0.37
77_R	80_M	0.509	0.37
362_I	398_L	0.508	0.37
219_T	232_A	0.508	0.37
46_G	50_L	0.507	0.37
453_S	528_L	0.506	0.37
49_F	80_M	0.506	0.37
328_G	379_L	0.505	0.37
406_S	544_A	0.505	0.37
220_V	287_E	0.505	0.37
311_L	392_I	0.505	0.37
491_V	505_L	0.505	0.37
302_R	441_P	0.504	0.37
96_W	398_L	0.504	0.37
94_K	139_S	0.504	0.37
84_C	189_A	0.504	0.37
406_S	557_I	0.504	0.37
62_D	477_T	0.504	0.37
472_I	538_W	0.504	0.37
217_K	481_N	0.503	0.37
155_V	283_L	0.503	0.37
350_K	385_I	0.503	0.37
56_G	150_D	0.503	0.37
162_Y	349_V	0.503	0.37
250_N	344_D	0.503	0.37
162_Y	399_I	0.502	0.36
52_I	75_E	0.502	0.36
385_I	417_E	0.502	0.36
133_V	189_A	0.501	0.36
91_I	142_L	0.501	0.36
458_I	528_L	0.500	0.36
250_N	272_S	0.500	0.36

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4g38A	1	0.7877	100	0.239	Contact Map
1zj8A	1	0.9158	100	0.289	Contact Map
3b0gA	1	0.8719	100	0.345	Contact Map
2akjA	1	0.8719	100	0.349	Contact Map
3or1A	2	0.5561	100	0.749	Contact Map
3mm5A	1	0.5123	100	0.759	Contact Map
3or1B	2	0.5351	100	0.765	Contact Map
3mm5B	2	0.5105	100	0.785	Contact Map
3noyA	2	0.5719	98.8	0.937	Contact Map
4s39A	2	0.614	91.6	0.97	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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