BETA - ECOLI - GREMLIN Contacts

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BETA - Oxygen-dependent choline dehydrogenase

UniProt:	P17444	Sequences: MQFDYIIIGAGSAGNVLATRLTEDPNTSVLLLEAGGPDYRFDFRTQMPAALAFPLQGKRYNWAYETEPEPFMNNRRMECGRGKGLGGSSLINGMCYIRGNALDLDNWAQEPGLENWSYLDCLPYYRKAETRDMGENDYHGGDGPVSVTTSKPGVNPLFEAMIEAGVQAGYPRTDDLNGYQQEGFGPMDRTVTPQGRRASTARGYLDQAKSRPNLTIRTHAMTDHIIFDGKRAVGVEWLEGDSTIPTRATANKEVLLCAGAIASPQILQRSGVGNAELLAEFDIPLVHELPGVGENLQDHLEMYLQYECKEPVSLYPALQWWNQPKIGAEWLFGGTGVGASNHFEAGGFIRSREEFAWPNIQYHFLPVAINYNGSNAVKEHGFQCHVGSMRSPSRGHVRIKSRDPHQHPAILFNYMSHEQDWQEFRDAIRITREIMHQPALDQYRGREISPGVECQTDEQLDEFVRNHAETAFHPCGTCKMGYDEMSVVDGEGRVHGLEGLRVVDASIMPQIITGNLNATTIMIGEKIADMIRGQEALPRSTAGYFVANGMPVRAKK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10109
Length:	556 (518)
Sequences:	11244 (8340)
Seq/√Len:	366.4

ECOLI - BETA
HALSA - Q9HQR8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
225_I	232_A	3.449	1.00
117_S	120_D	3.347	1.00
481_G	486_S	3.303	1.00
237_W	248_A	3.297	1.00
224_H	236_E	3.253	1.00
429_R	457_D	3.230	1.00
489_D	493_R	3.177	1.00
392_P	417_H	3.150	1.00
226_I	236_E	3.088	1.00
36_G	219_H	3.056	1.00
503_V	527_I	3.020	1.00
124_Y	529_D	3.019	1.00
130_T	142_D	2.994	1.00
456_T	459_Q	2.940	1.00
505_A	520_T	2.929	1.00
12_S	89_S	2.927	1.00
491_E	534_Q	2.884	1.00
263_S	478_C	2.865	1.00
121_C	522_M	2.850	1.00
265_Q	269_R	2.848	1.00
425_R	461_D	2.806	1.00
275_A	279_A	2.755	1.00
275_A	288_E	2.631	1.00
488_V	507_I	2.628	1.00
277_L	280_E	2.602	1.00
167_Q	439_A	2.595	1.00
253_E	501_R	2.516	1.00
294_E	396_H	2.511	1.00
403_D	406_Q	2.450	1.00
418_E	422_Q	2.328	1.00
401_S	406_Q	2.316	1.00
478_C	506_S	2.314	1.00
236_E	247_R	2.301	1.00
492_G	527_I	2.266	1.00
101_A	119_L	2.252	1.00
392_P	419_Q	2.232	1.00
520_T	524_G	2.213	1.00
3_F	30_L	2.201	1.00
268_Q	399_I	2.191	1.00
108_A	117_S	2.169	1.00
217_R	220_A	2.149	1.00
98_R	129_E	2.138	1.00
19_T	23_E	2.100	1.00
231_R	498_E	2.070	1.00
432_R	447_E	2.061	1.00
166_V	172_R	2.046	1.00
64_Y	262_A	2.038	1.00
6_I	248_A	2.037	1.00
526_K	530_M	2.029	1.00
231_R	499_G	2.004	1.00
226_I	234_G	1.994	1.00
430_I	433_E	1.978	1.00
24_D	532_R	1.966	1.00
30_L	248_A	1.965	1.00
220_A	237_W	1.925	1.00
508_M	523_I	1.923	1.00
32_L	220_A	1.921	1.00
491_E	533_G	1.915	1.00
462_E	466_N	1.910	1.00
400_K	409_A	1.910	1.00
268_Q	277_L	1.907	1.00
223_D	238_L	1.903	1.00
30_L	217_R	1.897	1.00
494_V	500_L	1.885	1.00
223_D	236_E	1.881	1.00
22_T	211_R	1.875	1.00
84_G	90_L	1.863	1.00
234_G	254_V	1.858	1.00
478_C	487_V	1.857	1.00
277_L	399_I	1.851	1.00
7_I	17_L	1.851	1.00
227_F	272_V	1.849	1.00
23_E	532_R	1.840	1.00
222_T	266_I	1.838	1.00
226_I	247_R	1.826	1.00
238_L	405_H	1.825	1.00
277_L	281_F	1.807	1.00
3_F	215_T	1.795	1.00
168_A	437_Q	1.782	1.00
294_E	398_R	1.771	1.00
421_W	461_D	1.768	1.00
127_K	529_D	1.767	1.00
69_E	411_L	1.766	1.00
32_L	237_W	1.746	1.00
268_Q	398_R	1.735	1.00
13_A	520_T	1.731	1.00
413_N	416_S	1.721	1.00
20_R	525_E	1.718	1.00
274_N	288_E	1.712	1.00
96_Y	518_A	1.704	1.00
200_T	521_I	1.702	1.00
475_C	511_I	1.702	1.00
5_Y	27_T	1.701	1.00
6_I	30_L	1.698	1.00
221_M	405_H	1.691	1.00
262_A	265_Q	1.690	1.00
32_L	217_R	1.674	1.00
486_S	495_H	1.659	1.00
67_E	409_A	1.652	1.00
82_G	88_S	1.648	1.00
507_I	523_I	1.646	1.00
163_E	166_V	1.640	1.00
115_N	120_D	1.634	1.00
24_D	27_T	1.633	1.00
228_D	233_V	1.624	1.00
287_H	497_L	1.617	1.00
491_E	530_M	1.598	1.00
12_S	517_N	1.594	1.00
85_L	218_T	1.585	1.00
277_L	294_E	1.581	1.00
227_F	286_V	1.580	1.00
124_Y	127_K	1.577	1.00
288_E	496_G	1.564	1.00
296_L	477_T	1.563	1.00
99_G	104_L	1.556	1.00
400_K	406_Q	1.554	1.00
396_H	411_L	1.551	1.00
503_V	524_G	1.527	1.00
8_I	225_I	1.526	1.00
10_A	85_L	1.524	1.00
291_G	485_M	1.507	1.00
128_A	521_I	1.505	1.00
227_F	230_K	1.504	1.00
127_K	525_E	1.492	1.00
15_N	200_T	1.487	1.00
106_N	510_Q	1.480	1.00
85_L	216_I	1.479	1.00
239_E	242_S	1.477	1.00
32_L	235_V	1.453	1.00
277_L	398_R	1.441	1.00
130_T	146_S	1.440	1.00
517_N	521_I	1.427	1.00
122_L	126_R	1.404	1.00
17_L	503_V	1.395	1.00
328_A	332_F	1.394	1.00
297_Q	394_R	1.390	1.00
27_T	532_R	1.386	1.00
233_V	249_T	1.383	1.00
279_A	285_L	1.380	1.00
306_Y	435_M	1.374	1.00
263_S	502_V	1.371	1.00
162_I	166_V	1.369	1.00
483_D	486_S	1.358	1.00
422_Q	461_D	1.355	1.00
428_I	460_L	1.346	1.00
255_L	531_I	1.345	1.00
226_I	233_V	1.344	1.00
261_I	397_V	1.343	1.00
326_I	329_E	1.333	1.00
217_R	239_E	1.328	1.00
10_A	15_N	1.327	1.00
145_V	203_G	1.320	1.00
198_A	203_G	1.312	1.00
492_G	507_I	1.310	1.00
458_E	461_D	1.300	1.00
16_V	521_I	1.296	1.00
274_N	294_E	1.296	1.00
73_N	466_N	1.295	1.00
204_Y	525_E	1.289	1.00
34_A	62_W	1.285	1.00
230_K	498_E	1.269	1.00
113_L	490_G	1.265	1.00
114_E	490_G	1.264	1.00
329_E	333_G	1.262	1.00
31_L	214_L	1.258	1.00
459_Q	462_E	1.257	1.00
479_K	483_D	1.251	1.00
209_K	216_I	1.249	1.00
479_K	485_M	1.242	1.00
307_E	446_R	1.238	1.00
81_R	88_S	1.237	1.00
438_P	442_Q	1.233	1.00
441_D	444_R	1.229	1.00
79_C	261_I	1.229	1.00
291_G	295_N	1.228	1.00
266_I	269_R	1.215	1.00
268_Q	294_E	1.211	1.00
361_Q	515_N	1.204	1.00
275_A	285_L	1.199	1.00
22_T	214_L	1.197	1.00
67_E	400_K	1.195	1.00
128_A	204_Y	1.194	1.00
268_Q	274_N	1.189	1.00
67_E	411_L	1.188	1.00
300_L	468_A	1.186	1.00
223_D	405_H	1.182	1.00
255_L	503_V	1.182	1.00
12_S	521_I	1.181	1.00
482_Y	490_G	1.180	1.00
146_S	198_A	1.175	1.00
274_N	277_L	1.173	1.00
159_E	163_E	1.172	1.00
69_E	412_F	1.165	1.00
239_E	244_I	1.162	1.00
422_Q	425_R	1.162	1.00
89_S	200_T	1.162	1.00
225_I	256_L	1.142	1.00
295_N	479_K	1.139	1.00
34_A	83_K	1.139	1.00
329_E	335_T	1.138	1.00
475_C	516_L	1.138	1.00
65_E	76_R	1.137	1.00
421_W	465_R	1.134	1.00
232_A	254_V	1.133	1.00
260_A	264_P	1.131	1.00
108_A	115_N	1.129	1.00
104_L	519_T	1.126	1.00
272_V	497_L	1.126	1.00
163_E	167_Q	1.125	1.00
28_S	215_T	1.121	1.00
497_L	500_L	1.121	1.00
16_V	204_Y	1.119	1.00
227_F	497_L	1.117	1.00
529_D	533_G	1.113	1.00
422_Q	426_D	1.111	1.00
230_K	287_H	1.109	1.00
516_L	520_T	1.102	1.00
325_K	329_E	1.101	1.00
167_Q	437_Q	1.094	1.00
19_T	208_A	1.094	1.00
99_G	125_Y	1.093	1.00
10_A	31_L	1.093	1.00
28_S	213_N	1.078	1.00
289_L	495_H	1.075	1.00
398_R	409_A	1.066	1.00
27_T	252_K	1.066	1.00
37_P	209_K	1.065	1.00
176_L	185_G	1.064	1.00
236_E	243_T	1.063	1.00
196_R	334_G	1.062	1.00
237_W	246_T	1.056	1.00
66_T	79_C	1.053	1.00
120_D	526_K	1.053	1.00
426_D	429_R	1.053	1.00
146_S	193_P	1.045	1.00
106_N	111_P	1.042	1.00
15_N	31_L	1.040	1.00
139_H	143_G	1.039	1.00
488_V	502_V	1.038	1.00
198_A	202_R	1.037	1.00
17_L	524_G	1.034	1.00
235_V	254_V	1.029	1.00
463_F	467_H	1.024	1.00
206_D	209_K	1.023	1.00
7_I	18_A	1.022	1.00
319_Q	322_N	1.019	1.00
133_M	149_T	1.017	1.00
493_R	498_E	1.015	1.00
352_R	355_F	1.015	1.00
527_I	531_I	1.014	1.00
113_L	482_Y	1.013	1.00
125_Y	522_M	1.007	1.00
493_R	501_R	1.005	1.00
281_F	402_R	1.004	1.00
336_G	339_A	1.002	1.00
8_I	258_A	1.001	1.00
396_H	413_N	0.995	1.00
327_G	330_W	0.995	1.00
3_F	6_I	0.994	1.00
291_G	479_K	0.993	1.00
292_V	487_V	0.992	1.00
20_R	127_K	0.986	1.00
438_P	441_D	0.986	1.00
261_I	410_I	0.985	1.00
101_A	105_D	0.982	1.00
88_S	91_I	0.982	1.00
239_E	243_T	0.981	1.00
425_R	457_D	0.980	1.00
17_L	255_L	0.980	1.00
281_F	399_I	0.978	1.00
349_I	430_I	0.977	1.00
326_I	337_V	0.974	1.00
187_M	346_G	0.970	1.00
419_Q	422_Q	0.967	1.00
269_R	404_P	0.967	1.00
433_E	436_H	0.966	1.00
17_L	528_A	0.966	1.00
144_P	204_Y	0.963	1.00
238_L	243_T	0.963	1.00
126_R	140_G	0.962	1.00
488_V	495_H	0.961	1.00
132_D	146_S	0.955	1.00
418_E	421_W	0.955	1.00
16_V	19_T	0.944	1.00
527_I	530_M	0.943	1.00
22_T	29_V	0.943	1.00
337_V	340_S	0.941	1.00
276_E	279_A	0.939	1.00
124_Y	526_K	0.938	1.00
104_L	125_Y	0.937	1.00
228_D	249_T	0.936	1.00
258_A	266_I	0.936	1.00
258_A	262_A	0.934	1.00
217_R	237_W	0.934	1.00
482_Y	495_H	0.933	1.00
226_I	249_T	0.930	1.00
291_G	486_S	0.930	1.00
250_A	254_V	0.926	1.00
223_D	269_R	0.924	1.00
130_T	144_P	0.923	1.00
8_I	235_V	0.921	1.00
223_D	243_T	0.918	1.00
47_M	50_A	0.915	1.00
516_L	519_T	0.911	1.00
141_G	145_V	0.908	1.00
97_I	514_G	0.908	1.00
97_I	515_N	0.904	1.00
201_A	206_D	0.903	1.00
384_C	431_T	0.903	1.00
37_P	85_L	0.898	1.00
96_Y	190_T	0.896	1.00
529_D	532_R	0.896	1.00
512_I	519_T	0.893	1.00
6_I	250_A	0.888	1.00
6_I	235_V	0.888	1.00
295_N	394_R	0.888	1.00
473_H	515_N	0.885	1.00
135_E	141_G	0.885	1.00
170_Y	430_I	0.884	1.00
297_Q	511_I	0.884	1.00
386_V	427_A	0.883	1.00
492_G	530_M	0.883	1.00
101_A	118_Y	0.883	1.00
503_V	531_I	0.879	1.00
219_H	240_G	0.878	1.00
225_I	500_L	0.877	1.00
227_F	233_V	0.874	1.00
22_T	213_N	0.874	1.00
98_R	122_L	0.873	1.00
45_T	84_G	0.871	1.00
260_A	475_C	0.870	1.00
128_A	525_E	0.866	1.00
6_I	254_V	0.866	1.00
298_D	470_T	0.866	1.00
325_K	328_A	0.864	1.00
268_Q	292_V	0.863	1.00
384_C	435_M	0.861	1.00
38_D	90_L	0.852	1.00
124_Y	525_E	0.852	1.00
5_Y	255_L	0.850	1.00
337_V	341_N	0.848	1.00
418_E	461_D	0.847	1.00
493_R	534_Q	0.845	1.00
419_Q	423_E	0.843	1.00
34_A	221_M	0.840	1.00
425_R	464_V	0.839	1.00
19_T	22_T	0.839	1.00
365_L	369_I	0.836	1.00
161_M	165_G	0.836	1.00
105_D	109_Q	0.836	1.00
232_A	500_L	0.834	1.00
225_I	254_V	0.834	1.00
73_N	462_E	0.833	1.00
72_M	75_R	0.833	1.00
338_G	341_N	0.832	1.00
488_V	492_G	0.831	1.00
160_A	443_Y	0.831	1.00
220_A	239_E	0.828	1.00
190_T	517_N	0.827	1.00
260_A	505_A	0.826	1.00
98_R	125_Y	0.825	1.00
38_D	84_G	0.824	1.00
257_C	503_V	0.822	1.00
193_P	198_A	0.822	1.00
118_Y	122_L	0.820	1.00
108_A	113_L	0.820	1.00
55_L	58_K	0.820	1.00
424_F	427_A	0.816	1.00
264_P	477_T	0.814	1.00
90_L	199_S	0.810	1.00
43_F	46_Q	0.809	1.00
120_D	123_P	0.808	1.00
230_K	286_V	0.808	1.00
130_T	141_G	0.807	1.00
170_Y	184_F	0.807	1.00
285_L	288_E	0.805	1.00
181_Q	187_M	0.800	1.00
228_D	231_R	0.800	1.00
324_P	328_A	0.799	1.00
111_P	510_Q	0.797	1.00
146_S	149_T	0.797	1.00
80_G	472_F	0.794	1.00
81_R	265_Q	0.791	1.00
184_F	347_G	0.791	1.00
256_L	263_S	0.791	1.00
8_I	256_L	0.790	1.00
19_T	207_Q	0.789	1.00
296_L	397_V	0.788	1.00
4_D	27_T	0.788	1.00
32_L	248_A	0.786	1.00
112_G	115_N	0.785	1.00
217_R	248_A	0.783	1.00
425_R	429_R	0.782	1.00
432_R	436_H	0.782	1.00
71_F	416_S	0.782	1.00
8_I	266_I	0.779	1.00
3_F	217_R	0.778	1.00
494_V	497_L	0.776	1.00
501_R	530_M	0.775	1.00
461_D	465_R	0.775	1.00
382_F	435_M	0.773	1.00
128_A	518_A	0.773	1.00
138_Y	178_G	0.772	1.00
160_A	163_E	0.771	1.00
309_K	445_G	0.770	1.00
136_N	141_G	0.766	1.00
106_N	109_Q	0.765	1.00
421_W	425_R	0.765	1.00
97_I	176_L	0.763	1.00
89_S	517_N	0.763	1.00
483_D	495_H	0.761	1.00
99_G	512_I	0.760	1.00
225_I	235_V	0.758	1.00
323_Q	326_I	0.756	1.00
370_N	373_G	0.752	1.00
274_N	398_R	0.752	1.00
398_R	411_L	0.751	1.00
145_V	150_S	0.750	1.00
140_G	145_V	0.749	1.00
505_A	508_M	0.748	1.00
148_T	151_K	0.747	1.00
167_Q	438_P	0.745	1.00
415_M	468_A	0.744	1.00
227_F	232_A	0.744	1.00
501_R	531_I	0.743	1.00
286_V	289_L	0.742	1.00
267_L	272_V	0.741	1.00
487_V	494_V	0.741	1.00
61_N	64_Y	0.739	1.00
435_M	440_L	0.738	1.00
44_R	48_P	0.738	1.00
66_T	69_E	0.736	1.00
84_G	91_I	0.736	1.00
261_I	474_P	0.735	1.00
5_Y	253_E	0.734	1.00
323_Q	327_G	0.734	1.00
327_G	331_L	0.734	1.00
145_V	149_T	0.733	1.00
297_Q	475_C	0.733	1.00
265_Q	399_I	0.731	1.00
286_V	494_V	0.731	1.00
20_R	528_A	0.730	1.00
202_R	206_D	0.727	1.00
20_R	23_E	0.727	1.00
387_G	471_A	0.725	1.00
224_H	286_V	0.725	1.00
102_L	105_D	0.725	1.00
139_H	175_D	0.725	1.00
175_D	178_G	0.724	1.00
162_I	172_R	0.723	1.00
165_G	184_F	0.722	1.00
129_E	139_H	0.721	1.00
278_L	285_L	0.720	1.00
114_E	482_Y	0.719	1.00
79_C	412_F	0.719	1.00
310_E	442_Q	0.718	1.00
253_E	531_I	0.717	1.00
36_G	218_T	0.717	1.00
111_P	115_N	0.717	1.00
31_L	205_L	0.717	1.00
267_L	478_C	0.716	1.00
134_G	141_G	0.716	1.00
18_A	31_L	0.714	0.99
462_E	465_R	0.713	0.99
426_D	430_I	0.712	0.99
480_M	488_V	0.712	0.99
131_R	188_D	0.712	0.99
309_K	441_D	0.711	0.99
263_S	504_D	0.711	0.99
24_D	211_R	0.708	0.99
154_V	159_E	0.705	0.99
165_G	170_Y	0.704	0.99
82_G	91_I	0.702	0.99
341_N	344_E	0.701	0.99
457_D	460_L	0.701	0.99
408_P	412_F	0.701	0.99
44_R	50_A	0.698	0.99
7_I	255_L	0.698	0.99
295_N	476_G	0.698	0.99
340_S	344_E	0.697	0.99
475_C	505_A	0.696	0.99
479_K	486_S	0.696	0.99
390_R	513_T	0.696	0.99
165_G	434_I	0.695	0.99
330_W	334_G	0.693	0.99
166_V	184_F	0.690	0.99
58_K	61_N	0.688	0.99
366_P	370_N	0.688	0.99
123_P	529_D	0.687	0.99
508_M	520_T	0.685	0.99
298_D	414_Y	0.685	0.99
272_V	286_V	0.685	0.99
291_G	487_V	0.685	0.99
238_L	241_D	0.685	0.99
139_H	147_V	0.683	0.99
361_Q	366_P	0.680	0.99
117_S	123_P	0.680	0.99
421_W	464_V	0.680	0.99
415_M	421_W	0.680	0.99
46_Q	196_R	0.679	0.99
358_P	361_Q	0.678	0.99
223_D	266_I	0.678	0.99
72_M	77_M	0.678	0.99
3_F	28_S	0.678	0.99
199_S	202_R	0.676	0.99
138_Y	179_Y	0.675	0.99
508_M	516_L	0.673	0.99
135_E	139_H	0.673	0.99
64_Y	410_I	0.673	0.99
429_R	432_R	0.669	0.99
15_N	205_L	0.669	0.99
428_I	464_V	0.669	0.99
66_T	412_F	0.669	0.99
96_Y	128_A	0.669	0.99
124_Y	128_A	0.668	0.99
201_A	205_L	0.668	0.99
105_D	108_A	0.668	0.99
352_R	426_D	0.667	0.99
324_P	327_G	0.667	0.99
388_S	423_E	0.667	0.99
307_E	379_E	0.666	0.99
19_T	211_R	0.665	0.99
46_Q	202_R	0.665	0.99
100_N	181_Q	0.664	0.99
322_N	325_K	0.663	0.99
336_G	341_N	0.662	0.99
182_E	350_R	0.660	0.99
154_V	158_F	0.660	0.99
209_K	212_P	0.659	0.99
280_E	398_R	0.659	0.99
350_R	354_E	0.659	0.99
436_H	441_D	0.657	0.99
65_E	78_E	0.657	0.99
307_E	445_G	0.657	0.99
178_G	181_Q	0.657	0.99
67_E	70_P	0.655	0.99
102_L	356_A	0.654	0.99
164_A	439_A	0.654	0.99
118_Y	179_Y	0.654	0.99
140_G	143_G	0.652	0.99
234_G	247_R	0.651	0.99
457_D	461_D	0.651	0.99
149_T	188_D	0.649	0.99
23_E	211_R	0.648	0.99
296_L	474_P	0.647	0.99
264_P	292_V	0.647	0.99
104_L	512_I	0.647	0.99
142_D	146_S	0.646	0.99
386_V	431_T	0.645	0.99
265_Q	281_F	0.644	0.99
287_H	495_H	0.644	0.99
163_E	172_R	0.642	0.99
26_N	29_V	0.642	0.99
388_S	391_S	0.641	0.99
43_F	47_M	0.640	0.99
299_H	515_N	0.640	0.99
220_A	248_A	0.639	0.99
108_A	114_E	0.638	0.99
121_C	125_Y	0.637	0.99
29_V	214_L	0.637	0.99
530_M	534_Q	0.637	0.99
162_I	184_F	0.637	0.99
489_D	495_H	0.635	0.99
104_L	121_C	0.635	0.99
113_L	120_D	0.634	0.99
136_N	139_H	0.634	0.99
508_M	512_I	0.632	0.99
143_G	146_S	0.632	0.99
281_F	285_L	0.632	0.99
274_N	285_L	0.632	0.99
492_G	523_I	0.631	0.99
48_P	51_L	0.631	0.99
145_V	148_T	0.631	0.99
139_H	145_V	0.630	0.99
187_M	191_V	0.629	0.99
224_H	270_S	0.629	0.99
62_W	83_K	0.627	0.99
5_Y	21_L	0.627	0.99
335_T	339_A	0.627	0.99
351_S	355_F	0.626	0.99
57_G	61_N	0.626	0.99
283_I	399_I	0.625	0.99
7_I	14_G	0.624	0.99
425_R	460_L	0.624	0.99
326_I	330_W	0.621	0.99
223_D	404_P	0.620	0.99
142_D	145_V	0.620	0.99
44_R	47_M	0.618	0.99
351_S	360_I	0.618	0.99
292_V	478_C	0.617	0.99
393_S	416_S	0.615	0.98
220_A	246_T	0.615	0.98
145_V	204_Y	0.614	0.98
54_P	58_K	0.614	0.98
42_D	60_Y	0.613	0.98
141_G	146_S	0.612	0.98
274_N	290_P	0.612	0.98
100_N	513_T	0.612	0.98
94_M	191_V	0.610	0.98
299_H	473_H	0.610	0.98
268_Q	397_V	0.610	0.98
143_G	147_V	0.610	0.98
458_E	462_E	0.610	0.98
66_T	70_P	0.609	0.98
302_M	463_F	0.607	0.98
250_A	500_L	0.606	0.98
156_P	160_A	0.606	0.98
396_H	409_A	0.605	0.98
322_N	326_I	0.605	0.98
83_K	221_M	0.605	0.98
108_A	120_D	0.604	0.98
79_C	474_P	0.604	0.98
481_G	485_M	0.604	0.98
67_E	76_R	0.603	0.98
205_L	208_A	0.602	0.98
108_A	112_G	0.602	0.98
54_P	57_G	0.600	0.98
7_I	29_V	0.599	0.98
360_I	427_A	0.597	0.98
336_G	340_S	0.597	0.98
340_S	343_F	0.597	0.98
184_F	187_M	0.596	0.98
221_M	265_Q	0.595	0.98
328_A	333_G	0.595	0.98
171_P	180_Q	0.594	0.98
166_V	171_P	0.594	0.98
159_E	186_P	0.592	0.98
105_D	119_L	0.591	0.98
107_W	508_M	0.590	0.98
302_M	424_F	0.590	0.98
23_E	525_E	0.589	0.98
131_R	149_T	0.587	0.98
434_I	437_Q	0.587	0.98
482_Y	485_M	0.585	0.98
478_C	488_V	0.584	0.98
323_Q	328_A	0.584	0.98
429_R	460_L	0.583	0.98
168_A	433_E	0.583	0.98
39_Y	43_F	0.582	0.98
233_V	247_R	0.582	0.98
422_Q	457_D	0.580	0.98
276_E	280_E	0.580	0.98
289_L	497_L	0.579	0.98
305_Q	383_Q	0.579	0.98
69_E	72_M	0.578	0.98
105_D	118_Y	0.577	0.98
73_N	465_R	0.577	0.98
526_K	529_D	0.576	0.98
439_A	442_Q	0.576	0.98
45_T	48_P	0.576	0.98
104_L	107_W	0.575	0.98
7_I	22_T	0.575	0.98
105_D	117_S	0.572	0.98
367_V	370_N	0.572	0.98
174_D	178_G	0.571	0.98
407_H	410_I	0.571	0.98
38_D	46_Q	0.571	0.98
141_G	144_P	0.570	0.98
456_T	460_L	0.570	0.98
427_A	431_T	0.568	0.97
118_Y	121_C	0.568	0.97
366_P	369_I	0.567	0.97
115_N	490_G	0.566	0.97
301_E	471_A	0.565	0.97
24_D	213_N	0.565	0.97
530_M	533_G	0.564	0.97
102_L	357_W	0.563	0.97
10_A	13_A	0.563	0.97
39_Y	42_D	0.563	0.97
482_Y	486_S	0.562	0.97
256_L	266_I	0.562	0.97
135_E	138_Y	0.562	0.97
158_F	162_I	0.562	0.97
325_K	330_W	0.562	0.97
147_V	150_S	0.559	0.97
232_A	497_L	0.559	0.97
262_A	266_I	0.559	0.97
50_A	54_P	0.558	0.97
45_T	60_Y	0.558	0.97
368_A	372_N	0.558	0.97
295_N	477_T	0.558	0.97
56_Q	59_R	0.558	0.97
137_D	141_G	0.557	0.97
304_L	428_I	0.557	0.97
358_P	363_H	0.556	0.97
22_T	208_A	0.556	0.97
346_G	349_I	0.555	0.97
321_W	324_P	0.555	0.97
181_Q	191_V	0.554	0.97
141_G	147_V	0.553	0.97
14_G	257_C	0.553	0.97
302_M	464_V	0.550	0.97
7_I	19_T	0.550	0.97
45_T	90_L	0.550	0.97
511_I	516_L	0.548	0.97
400_K	407_H	0.548	0.97
417_H	421_W	0.547	0.97
320_W	323_Q	0.546	0.97
294_E	393_S	0.546	0.97
122_L	138_Y	0.546	0.97
153_G	156_P	0.545	0.97
281_F	401_S	0.544	0.97
333_G	339_A	0.544	0.97
147_V	151_K	0.543	0.97
328_A	334_G	0.543	0.97
281_F	284_P	0.542	0.97
476_G	479_K	0.541	0.97
43_F	50_A	0.541	0.97
155_N	158_F	0.541	0.97
365_L	368_A	0.541	0.97
279_A	284_P	0.541	0.97
12_S	200_T	0.538	0.97
475_C	508_M	0.538	0.97
61_N	91_I	0.538	0.97
291_G	495_H	0.538	0.97
227_F	287_H	0.537	0.96
68_P	71_F	0.535	0.96
240_G	243_T	0.534	0.96
145_V	190_T	0.534	0.96
291_G	294_E	0.533	0.96
139_H	144_P	0.533	0.96
4_D	252_K	0.533	0.96
131_R	139_H	0.532	0.96
277_L	288_E	0.532	0.96
67_E	71_F	0.531	0.96
503_V	528_A	0.531	0.96
181_Q	196_R	0.531	0.96
260_A	474_P	0.530	0.96
127_K	528_A	0.530	0.96
42_D	45_T	0.530	0.96
23_E	127_K	0.529	0.96
328_A	331_L	0.529	0.96
113_L	116_W	0.528	0.96
433_E	437_Q	0.526	0.96
283_I	290_P	0.526	0.96
79_C	414_Y	0.526	0.96
19_T	144_P	0.526	0.96
222_T	258_A	0.525	0.96
115_N	526_K	0.525	0.96
106_N	390_R	0.525	0.96
95_C	187_M	0.523	0.96
324_P	332_F	0.523	0.96
322_N	328_A	0.523	0.96
249_T	252_K	0.523	0.96
98_R	126_R	0.522	0.96
403_D	408_P	0.521	0.96
203_G	207_Q	0.521	0.96
164_A	167_Q	0.519	0.96
359_N	362_Y	0.518	0.96
17_L	527_I	0.517	0.96
239_E	246_T	0.516	0.96
359_N	364_F	0.515	0.96
330_W	333_G	0.515	0.96
502_V	506_S	0.515	0.96
269_R	399_I	0.513	0.95
421_W	424_F	0.512	0.95
481_G	495_H	0.512	0.95
59_R	63_A	0.512	0.95
261_I	265_Q	0.512	0.95
361_Q	365_L	0.510	0.95
492_G	503_V	0.510	0.95
272_V	292_V	0.509	0.95
208_A	214_L	0.507	0.95
330_W	336_G	0.506	0.95
123_P	526_K	0.506	0.95
272_V	287_H	0.505	0.95
210_S	213_N	0.505	0.95
238_L	242_S	0.505	0.95
232_A	499_G	0.504	0.95
308_C	382_F	0.503	0.95
358_P	366_P	0.502	0.95
297_Q	476_G	0.502	0.95
502_V	507_I	0.502	0.95
5_Y	532_R	0.501	0.95
258_A	263_S	0.501	0.95
447_E	450_P	0.500	0.95
12_S	31_L	0.500	0.95

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3fimB	1	0.955	100	0.214	Contact Map
4h7uA	1	0.946	100	0.221	Contact Map
4udqA	1	0.8885	100	0.246	Contact Map
1gpeA	2	0.9496	100	0.247	Contact Map
2jbvA	1	0.9119	100	0.25	Contact Map
3qvpA	1	0.9514	100	0.252	Contact Map
4ha6A	2	0.9029	100	0.257	Contact Map
3q9tA	2	0.9442	100	0.258	Contact Map
4z24A	2	0.9371	100	0.315	Contact Map
1ju2A	1	0.8615	100	0.327	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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