CIRA - ECOLI - GREMLIN Contacts

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CIRA - Colicin I receptor

UniProt:	P17315	Sequences: MFRLNPFVRVGLCLSAISCAWPVLAVDDDGETMVVTASSVEQNLKDAPASISVITQEDLQRKPVQNLKDVLKEVPGVQLTNEGDNRKGVSIRGLDSSYTLILVDGKRVNSRNAVFRHNDFDLNWIPVDSIERIEVVRGPMSSLYGSDALGGVVNIITKKIGQKWSGTVTVDTTIQEHRDRGDTYNGQFFTSGPLIDGVLGMKAYGSLAKREKDDPQNSTTTDTGETPRIEGFSSRDGNVEFAWTPNQNHDFTAGYGFDRQDRDSDSLDKNRLERQNYSVSHNGRWDYGTSELKYYGEKVENKNPGNSSPITSESNTVDGKYTLPLTAINQFLTVGGEWRHDKLSDAVNLTGGTSSKTSASQYALFVEDEWRIFEPLALTTGVRMDDHETYGEHWSPRAYLVYNATDTVTVKGGWATAFKAPSLLQLSPDWTSNSCRGACKIVGSPDLKPETSESWELGLYYMGEEGWLEGVESSVTVFRNDVKDRISISRTSDVNAAPGYQNFVGFETGANGRRIPVFSYYNVNKARIQGVETELKIPFNDEWKLSINYTYNDGRDVSNGENKPLSDLPFHTANGTLDWKPLALEDWSFYVSGHYTGQKRADSATAKTPGGYTIWNTGAAWQVTKDVKLRAGVLNLGDKDLSRDDYSYNEDGRRYFMAVDYRF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10155
Length:	663 (578)
Sequences:	53061 (43761)
Seq/√Len:	1820.2

ECOLI - CIRA FHUE FHUA YNCD FEPA BTUB FIU YDDB FECA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
549_Y	571_H	4.009	1.00
199_L	243_W	3.780	1.00
593_G	613_T	3.711	1.00
382_V	394_W	3.474	1.00
479_R	529_Q	3.434	1.00
408_V	459_L	3.391	1.00
414_W	453_E	3.364	1.00
249_H	283_G	3.296	1.00
630_R	658_A	3.248	1.00
416_T	453_E	3.132	1.00
207_L	235_R	3.038	1.00
588_S	620_A	3.008	1.00
384_M	394_W	2.991	1.00
330_Q	368_D	2.927	1.00
546_S	576_T	2.712	1.00
408_V	461_Y	2.674	1.00
252_T	280_S	2.666	1.00
205_G	235_R	2.654	1.00
249_H	281_H	2.463	1.00
376_L	402_Y	2.438	1.00
479_R	527_R	2.437	1.00
471_V	537_I	2.402	1.00
257_F	275_Q	2.388	1.00
56_Q	60_Q	2.361	1.00
375_P	402_Y	2.355	1.00
615_W	637_G	2.334	1.00
250_D	282_N	2.333	1.00
384_M	392_E	2.284	1.00
132_R	156_I	2.265	1.00
461_Y	473_S	2.237	1.00
255_Y	275_Q	2.236	1.00
168_V	186_G	2.223	1.00
199_L	241_F	2.212	1.00
192_G	201_M	2.191	1.00
551_Y	571_H	2.186	1.00
248_N	283_G	2.169	1.00
593_G	615_W	2.166	1.00
633_V	636_L	2.161	1.00
170_V	186_G	2.160	1.00
130_I	155_I	2.149	1.00
335_G	365_F	2.139	1.00
543_W	577_L	2.136	1.00
595_Y	613_T	2.111	1.00
632_G	656_F	2.100	1.00
55_T	58_D	2.064	1.00
246_N	249_H	2.052	1.00
472_E	536_K	2.046	1.00
591_V	615_W	2.034	1.00
590_Y	618_G	2.028	1.00
209_K	233_S	2.024	1.00
404_A	410_V	1.987	1.00
200_G	242_A	1.985	1.00
620_A	628_K	1.979	1.00
474_S	534_E	1.970	1.00
628_K	660_D	1.923	1.00
166_G	190_T	1.900	1.00
401_V	409_T	1.897	1.00
340_H	360_S	1.891	1.00
416_T	451_T	1.887	1.00
259_R	273_E	1.878	1.00
169_T	187_Q	1.870	1.00
336_G	362_Y	1.851	1.00
414_W	455_W	1.842	1.00
622_Q	628_K	1.835	1.00
376_L	400_L	1.801	1.00
627_V	661_Y	1.775	1.00
203_A	239_V	1.770	1.00
598_Q	608_T	1.766	1.00
477_V	529_Q	1.763	1.00
404_A	408_V	1.754	1.00
377_A	403_N	1.744	1.00
544_K	578_D	1.716	1.00
251_F	281_H	1.712	1.00
66_N	69_D	1.710	1.00
103_V	108_V	1.709	1.00
242_A	250_D	1.700	1.00
255_Y	277_Y	1.697	1.00
330_Q	370_W	1.692	1.00
542_E	579_W	1.680	1.00
169_T	660_D	1.675	1.00
573_A	595_Y	1.673	1.00
485_R	526_A	1.669	1.00
592_S	616_N	1.656	1.00
489_S	521_Y	1.655	1.00
206_S	236_D	1.644	1.00
473_S	535_L	1.641	1.00
543_W	579_W	1.637	1.00
396_P	416_T	1.621	1.00
587_W	621_W	1.613	1.00
453_E	483_K	1.613	1.00
488_I	520_Y	1.609	1.00
454_S	480_N	1.605	1.00
104_D	240_E	1.599	1.00
481_D	525_K	1.593	1.00
329_N	373_F	1.592	1.00
338_W	362_Y	1.580	1.00
481_D	527_R	1.566	1.00
53_V	134_E	1.562	1.00
478_F	552_N	1.561	1.00
460_Y	474_S	1.560	1.00
631_A	655_Y	1.556	1.00
131_E	158_K	1.555	1.00
201_M	241_F	1.554	1.00
475_V	533_T	1.541	1.00
74_V	135_V	1.539	1.00
627_V	659_V	1.538	1.00
403_N	407_T	1.536	1.00
595_Y	611_G	1.535	1.00
242_A	252_T	1.533	1.00
244_T	250_D	1.532	1.00
292_L	319_G	1.528	1.00
282_N	289_T	1.526	1.00
331_F	371_R	1.521	1.00
162_Q	200_G	1.517	1.00
641_L	650_E	1.513	1.00
201_M	205_G	1.509	1.00
411_K	458_G	1.507	1.00
167_T	662_R	1.503	1.00
633_V	655_Y	1.498	1.00
411_K	460_Y	1.495	1.00
470_G	537_I	1.493	1.00
282_N	291_E	1.492	1.00
536_K	546_S	1.490	1.00
545_L	577_L	1.484	1.00
405_T	408_V	1.478	1.00
57_E	61_R	1.478	1.00
253_A	277_Y	1.475	1.00
448_K	484_D	1.463	1.00
371_R	377_A	1.460	1.00
340_H	358_S	1.451	1.00
471_V	535_L	1.450	1.00
588_S	622_Q	1.448	1.00
134_E	154_N	1.446	1.00
18_S	21_W	1.443	1.00
56_Q	158_K	1.433	1.00
478_F	530_G	1.427	1.00
623_V	629_L	1.422	1.00
91_I	151_G	1.418	1.00
198_V	243_W	1.414	1.00
103_V	157_T	1.408	1.00
545_L	575_G	1.399	1.00
529_Q	553_D	1.398	1.00
363_A	385_D	1.397	1.00
396_P	400_L	1.396	1.00
43_N	46_D	1.395	1.00
363_A	383_R	1.392	1.00
410_V	459_L	1.387	1.00
487_S	523_V	1.385	1.00
576_T	592_S	1.383	1.00
617_T	636_L	1.380	1.00
92_R	532_E	1.376	1.00
462_M	469_E	1.376	1.00
451_T	484_D	1.368	1.00
462_M	472_E	1.366	1.00
171_D	185_N	1.365	1.00
20_A	23_V	1.364	1.00
377_A	401_V	1.356	1.00
131_E	159_K	1.351	1.00
627_V	631_A	1.350	1.00
633_V	653_R	1.346	1.00
475_V	531_V	1.343	1.00
58_D	61_R	1.338	1.00
203_A	237_G	1.337	1.00
456_E	476_T	1.331	1.00
399_Y	413_G	1.330	1.00
296_G	315_N	1.321	1.00
586_D	621_W	1.320	1.00
172_T	184_Y	1.312	1.00
251_F	279_V	1.311	1.00
578_D	590_Y	1.310	1.00
200_G	244_T	1.309	1.00
618_G	630_R	1.307	1.00
164_W	190_T	1.305	1.00
207_L	233_S	1.303	1.00
189_F	202_K	1.298	1.00
594_H	616_N	1.297	1.00
173_T	183_T	1.295	1.00
331_F	369_E	1.292	1.00
159_K	242_A	1.291	1.00
419_K	450_E	1.289	1.00
328_I	335_G	1.289	1.00
539_F	545_L	1.282	1.00
57_E	60_Q	1.279	1.00
166_G	170_V	1.279	1.00
62_K	73_E	1.278	1.00
629_L	659_V	1.278	1.00
548_N	574_N	1.276	1.00
250_D	284_R	1.274	1.00
294_Y	315_N	1.265	1.00
412_G	455_W	1.262	1.00
571_H	597_G	1.261	1.00
367_E	379_T	1.258	1.00
167_T	189_F	1.257	1.00
411_K	476_T	1.257	1.00
104_D	157_T	1.252	1.00
171_D	658_A	1.251	1.00
588_S	628_K	1.248	1.00
380_T	398_A	1.247	1.00
378_L	400_L	1.243	1.00
159_K	240_E	1.243	1.00
369_E	379_T	1.240	1.00
527_R	557_V	1.239	1.00
288_G	323_L	1.239	1.00
76_G	550_T	1.238	1.00
254_G	278_S	1.236	1.00
318_D	337_E	1.233	1.00
547_I	575_G	1.233	1.00
104_D	254_G	1.232	1.00
280_S	291_E	1.225	1.00
205_G	237_G	1.221	1.00
587_W	619_A	1.219	1.00
284_R	289_T	1.215	1.00
544_K	580_K	1.214	1.00
201_M	239_V	1.213	1.00
167_T	660_D	1.209	1.00
126_P	129_S	1.208	1.00
245_P	251_F	1.208	1.00
291_E	320_K	1.207	1.00
337_E	363_A	1.205	1.00
408_V	412_G	1.203	1.00
290_S	321_Y	1.202	1.00
321_Y	325_L	1.201	1.00
319_G	323_L	1.201	1.00
538_P	544_K	1.200	1.00
323_L	326_T	1.197	1.00
285_W	290_S	1.194	1.00
373_F	376_L	1.190	1.00
589_F	619_A	1.189	1.00
657_M	661_Y	1.188	1.00
385_D	395_S	1.186	1.00
257_F	273_E	1.185	1.00
164_W	168_V	1.182	1.00
616_N	634_L	1.173	1.00
248_N	284_R	1.173	1.00
290_S	319_G	1.172	1.00
324_P	331_F	1.170	1.00
634_L	654_R	1.169	1.00
455_W	481_D	1.167	1.00
457_L	477_V	1.166	1.00
92_R	456_E	1.164	1.00
458_G	476_T	1.163	1.00
477_V	531_V	1.161	1.00
455_W	479_R	1.156	1.00
165_S	191_S	1.156	1.00
620_A	630_R	1.154	1.00
338_W	360_S	1.153	1.00
170_V	184_Y	1.152	1.00
628_K	662_R	1.149	1.00
550_T	572_T	1.148	1.00
473_S	533_T	1.138	1.00
52_S	137_R	1.135	1.00
69_D	72_K	1.131	1.00
403_N	406_D	1.129	1.00
202_K	240_E	1.125	1.00
375_P	404_A	1.124	1.00
596_T	599_K	1.121	1.00
531_V	551_Y	1.119	1.00
75_P	534_E	1.115	1.00
252_T	282_N	1.115	1.00
164_W	192_G	1.109	1.00
204_Y	238_N	1.108	1.00
327_A	373_F	1.108	1.00
623_V	627_V	1.100	1.00
253_A	279_V	1.098	1.00
328_I	370_W	1.097	1.00
237_G	257_F	1.083	1.00
288_G	325_L	1.082	1.00
536_K	544_K	1.081	1.00
417_A	452_S	1.076	1.00
400_L	404_A	1.070	1.00
168_V	172_T	1.067	1.00
77_V	91_I	1.066	1.00
137_R	532_E	1.065	1.00
591_V	617_T	1.061	1.00
631_A	657_M	1.058	1.00
259_R	271_R	1.058	1.00
149_L	452_S	1.058	1.00
336_G	364_L	1.055	1.00
615_W	639_K	1.055	1.00
330_Q	335_G	1.053	1.00
580_K	588_S	1.053	1.00
540_N	543_W	1.050	1.00
318_D	323_L	1.048	1.00
412_G	457_L	1.047	1.00
573_A	597_G	1.040	1.00
329_N	370_W	1.040	1.00
407_T	461_Y	1.038	1.00
452_S	480_N	1.037	1.00
16_A	19_C	1.036	1.00
106_K	295_Y	1.034	1.00
528_I	554_G	1.034	1.00
577_L	591_V	1.031	1.00
78_Q	572_T	1.029	1.00
371_R	374_E	1.028	1.00
369_E	377_A	1.021	1.00
578_D	588_S	1.020	1.00
56_Q	131_E	1.018	1.00
379_T	399_Y	1.018	1.00
256_G	276_N	1.014	1.00
295_Y	316_T	1.014	1.00
483_K	525_K	1.012	1.00
393_H	451_T	1.011	1.00
134_E	156_I	1.008	1.00
378_L	398_A	1.008	1.00
46_D	403_N	1.006	1.00
410_V	457_L	1.006	1.00
364_L	384_M	1.005	1.00
551_Y	570_F	1.001	1.00
135_V	153_V	1.000	1.00
102_L	107_R	0.997	1.00
594_H	614_I	0.995	1.00
615_W	636_L	0.995	1.00
131_E	156_I	0.993	1.00
614_I	641_L	0.991	1.00
332_L	368_D	0.990	1.00
184_Y	209_K	0.989	1.00
292_L	317_V	0.986	1.00
404_A	459_L	0.985	1.00
362_Y	386_D	0.984	1.00
129_S	204_Y	0.978	1.00
231_G	263_D	0.978	1.00
280_S	293_K	0.978	1.00
48_P	399_Y	0.971	1.00
251_F	255_Y	0.970	1.00
337_E	365_F	0.969	1.00
403_N	409_T	0.969	1.00
618_G	632_G	0.968	1.00
419_K	425_Q	0.967	1.00
463_G	473_S	0.967	1.00
400_L	412_G	0.966	1.00
473_S	477_V	0.966	1.00
100_L	107_R	0.965	1.00
459_L	475_V	0.958	1.00
542_E	580_K	0.957	1.00
29_D	32_T	0.956	1.00
359_A	389_T	0.953	1.00
545_L	552_N	0.948	1.00
478_F	532_E	0.947	1.00
463_G	471_V	0.946	1.00
630_R	660_D	0.945	1.00
74_V	77_V	0.945	1.00
320_K	323_L	0.945	1.00
596_T	612_Y	0.945	1.00
186_G	207_L	0.944	1.00
452_S	482_V	0.944	1.00
162_Q	197_G	0.943	1.00
386_D	392_E	0.943	1.00
245_P	249_H	0.941	1.00
53_V	132_R	0.940	1.00
240_E	252_T	0.935	1.00
244_T	247_Q	0.933	1.00
629_L	657_M	0.933	1.00
622_Q	662_R	0.927	1.00
470_G	538_P	0.926	1.00
126_P	206_S	0.923	1.00
395_S	418_F	0.922	1.00
619_A	633_V	0.920	1.00
298_K	313_E	0.919	1.00
142_S	381_G	0.918	1.00
102_L	154_N	0.913	1.00
18_S	22_P	0.912	1.00
537_I	545_L	0.909	1.00
185_N	206_S	0.905	1.00
21_W	24_L	0.903	1.00
475_V	479_R	0.903	1.00
381_G	397_R	0.901	1.00
22_P	25_A	0.899	1.00
328_I	337_E	0.897	1.00
315_N	319_G	0.897	1.00
455_W	459_L	0.896	1.00
396_P	414_W	0.895	1.00
128_D	187_Q	0.894	1.00
164_W	201_M	0.893	1.00
48_P	401_V	0.889	1.00
370_W	380_T	0.889	1.00
187_Q	206_S	0.888	1.00
291_E	322_T	0.887	1.00
409_T	460_Y	0.886	1.00
169_T	658_A	0.884	1.00
168_V	188_F	0.882	1.00
198_V	245_P	0.882	1.00
597_G	611_G	0.881	1.00
61_R	578_D	0.881	1.00
64_V	70_V	0.880	1.00
102_L	152_V	0.880	1.00
144_Y	152_V	0.879	1.00
59_L	70_V	0.874	1.00
334_V	366_V	0.874	1.00
289_T	322_T	0.873	1.00
539_F	577_L	0.873	1.00
549_Y	573_A	0.871	1.00
372_I	378_L	0.869	1.00
526_A	565_L	0.867	1.00
284_R	287_Y	0.866	1.00
382_V	396_P	0.864	1.00
183_T	210_R	0.864	1.00
387_H	420_A	0.863	1.00
538_P	541_D	0.862	1.00
634_L	656_F	0.862	1.00
422_S	425_Q	0.862	1.00
75_P	548_N	0.861	1.00
614_I	650_E	0.861	1.00
129_S	238_N	0.859	1.00
253_A	257_F	0.859	1.00
101_I	153_V	0.857	1.00
58_D	73_E	0.856	1.00
329_N	371_R	0.854	1.00
261_D	271_R	0.853	1.00
290_S	294_Y	0.851	1.00
129_S	202_K	0.850	1.00
636_L	653_R	0.850	1.00
52_S	534_E	0.850	1.00
626_D	661_Y	0.849	1.00
186_G	190_T	0.846	1.00
598_Q	611_G	0.846	1.00
320_K	325_L	0.845	1.00
629_L	633_V	0.844	1.00
166_G	188_F	0.844	1.00
316_T	320_K	0.844	1.00
188_F	192_G	0.843	1.00
638_D	652_G	0.839	1.00
451_T	483_K	0.839	1.00
246_N	283_G	0.838	1.00
327_A	330_Q	0.835	1.00
73_E	592_S	0.835	1.00
556_D	559_N	0.833	1.00
334_V	338_W	0.832	1.00
67_L	155_I	0.829	1.00
584_L	587_W	0.827	1.00
159_K	252_T	0.827	1.00
450_E	482_V	0.827	1.00
274_R	297_E	0.826	1.00
463_G	469_E	0.823	1.00
547_I	573_A	0.823	1.00
315_N	318_D	0.821	1.00
425_Q	520_Y	0.821	1.00
489_S	492_S	0.820	1.00
285_W	288_G	0.818	1.00
107_R	147_D	0.818	1.00
398_A	414_W	0.817	1.00
580_K	622_Q	0.815	1.00
294_Y	317_V	0.814	1.00
165_S	662_R	0.814	1.00
161_G	165_S	0.814	1.00
185_N	208_A	0.813	1.00
54_I	74_V	0.812	1.00
164_W	193_P	0.812	1.00
552_N	568_L	0.811	1.00
599_K	610_G	0.809	1.00
245_P	281_H	0.808	1.00
364_L	368_D	0.807	1.00
191_S	202_K	0.806	1.00
318_D	322_T	0.805	1.00
76_G	137_R	0.804	1.00
89_V	101_I	0.803	1.00
237_G	241_F	0.803	1.00
161_G	191_S	0.802	1.00
89_V	153_V	0.802	1.00
160_I	200_G	0.800	1.00
106_K	293_K	0.799	1.00
625_K	661_Y	0.799	1.00
239_V	243_W	0.799	1.00
47_A	51_I	0.796	1.00
325_L	332_L	0.795	1.00
317_V	321_Y	0.794	1.00
91_I	135_V	0.794	1.00
52_S	74_V	0.794	1.00
488_I	518_F	0.794	1.00
533_T	537_I	0.793	1.00
171_D	656_F	0.792	1.00
319_G	322_T	0.790	1.00
30_G	33_M	0.789	1.00
51_I	134_E	0.788	1.00
586_D	622_Q	0.788	1.00
364_L	386_D	0.787	1.00
193_P	200_G	0.785	1.00
235_R	239_V	0.785	1.00
617_T	633_V	0.783	1.00
610_G	639_K	0.783	1.00
209_K	231_G	0.782	1.00
367_E	397_R	0.782	1.00
613_T	639_K	0.782	1.00
50_S	456_E	0.780	1.00
478_F	550_T	0.779	1.00
482_V	485_R	0.778	1.00
203_A	207_L	0.778	1.00
283_G	286_D	0.774	1.00
198_V	244_T	0.773	1.00
407_T	462_M	0.773	1.00
208_A	234_S	0.773	1.00
344_S	356_K	0.773	1.00
573_A	577_L	0.771	1.00
471_V	475_V	0.771	1.00
490_R	518_F	0.770	1.00
453_E	481_D	0.769	1.00
542_E	545_L	0.769	1.00
626_D	662_R	0.769	1.00
160_I	242_A	0.769	1.00
167_T	170_V	0.767	1.00
450_E	485_R	0.767	1.00
72_K	594_H	0.767	1.00
320_K	365_F	0.767	1.00
379_T	401_V	0.765	1.00
333_T	369_E	0.765	1.00
281_H	292_L	0.764	1.00
570_F	597_G	0.762	1.00
21_W	25_A	0.762	1.00
573_A	613_T	0.761	1.00
235_R	259_R	0.760	1.00
531_V	535_L	0.758	1.00
133_I	155_I	0.757	1.00
571_H	595_Y	0.756	1.00
79_L	89_V	0.756	1.00
535_L	547_I	0.753	1.00
30_G	34_V	0.750	1.00
426_L	429_D	0.750	1.00
238_N	256_G	0.750	1.00
361_Q	420_A	0.749	1.00
289_T	324_P	0.747	1.00
576_T	590_Y	0.747	1.00
261_D	269_K	0.746	1.00
318_D	325_L	0.745	1.00
546_S	578_D	0.743	1.00
425_Q	428_P	0.742	1.00
182_D	211_E	0.741	1.00
90_S	95_D	0.741	1.00
366_V	382_V	0.741	1.00
293_K	318_D	0.739	1.00
105_G	154_N	0.738	1.00
277_Y	296_G	0.738	1.00
213_D	652_G	0.737	1.00
600_R	609_P	0.734	1.00
189_F	204_Y	0.732	1.00
92_R	478_F	0.731	1.00
127_V	130_I	0.731	1.00
315_N	323_L	0.730	1.00
65_Q	69_D	0.729	1.00
326_T	329_N	0.728	1.00
553_D	570_F	0.728	1.00
92_R	530_G	0.727	1.00
589_F	617_T	0.725	1.00
622_Q	626_D	0.725	1.00
395_S	416_T	0.725	1.00
16_A	20_A	0.725	1.00
199_L	203_A	0.724	1.00
56_Q	59_L	0.722	1.00
342_K	356_K	0.722	1.00
200_G	250_D	0.721	1.00
175_Q	183_T	0.717	1.00
316_T	319_G	0.715	1.00
202_K	238_N	0.715	1.00
556_D	560_G	0.715	1.00
342_K	358_S	0.714	1.00
19_C	22_P	0.713	1.00
564_P	570_F	0.712	1.00
52_S	75_P	0.711	1.00
128_D	169_T	0.711	1.00
136_V	144_Y	0.710	1.00
78_Q	569_P	0.710	1.00
298_K	311_T	0.708	1.00
480_N	528_I	0.708	1.00
624_T	627_V	0.708	1.00
469_E	473_S	0.707	1.00
100_L	148_A	0.705	1.00
333_T	337_E	0.705	1.00
482_V	526_A	0.704	1.00
243_W	246_N	0.704	1.00
472_E	538_P	0.702	1.00
534_E	546_S	0.702	1.00
285_W	321_Y	0.700	1.00
580_K	586_D	0.699	1.00
106_K	278_S	0.698	1.00
396_P	399_Y	0.696	1.00
67_L	70_V	0.695	1.00
375_P	406_D	0.692	1.00
545_L	550_T	0.691	1.00
147_D	361_Q	0.691	1.00
321_Y	326_T	0.691	1.00
535_L	539_F	0.689	1.00
600_R	608_T	0.688	1.00
136_V	152_V	0.687	1.00
100_L	152_V	0.686	1.00
333_T	367_E	0.686	1.00
26_V	29_D	0.686	1.00
199_L	245_P	0.684	1.00
143_L	333_T	0.684	1.00
61_R	588_S	0.684	1.00
193_P	196_D	0.683	1.00
168_V	661_Y	0.682	1.00
375_P	403_N	0.680	1.00
128_D	167_T	0.679	1.00
139_P	415_A	0.679	1.00
275_Q	298_K	0.678	1.00
296_G	313_E	0.678	1.00
332_L	366_V	0.678	1.00
545_L	548_N	0.678	1.00
557_V	560_G	0.676	1.00
527_R	555_R	0.675	1.00
316_T	323_L	0.674	1.00
632_G	658_A	0.674	1.00
283_G	287_Y	0.674	1.00
50_S	476_T	0.674	1.00
17_I	20_A	0.674	1.00
60_Q	660_D	0.672	1.00
368_D	380_T	0.672	1.00
44_L	53_V	0.670	1.00
173_T	656_F	0.669	1.00
19_C	23_V	0.669	1.00
240_E	254_G	0.669	1.00
397_R	413_G	0.669	1.00
423_L	426_L	0.668	1.00
405_T	461_Y	0.668	1.00
175_Q	654_R	0.668	1.00
544_K	547_I	0.668	1.00
637_G	640_D	0.667	1.00
94_L	150_G	0.664	1.00
638_D	653_R	0.663	1.00
360_S	388_E	0.662	1.00
18_S	23_V	0.662	1.00
330_Q	334_V	0.662	1.00
320_K	324_P	0.661	1.00
425_Q	429_D	0.661	1.00
260_Q	272_L	0.661	1.00
537_I	540_N	0.660	1.00
372_I	400_L	0.657	1.00
212_K	230_E	0.656	1.00
651_D	654_R	0.655	1.00
327_A	332_L	0.655	1.00
579_W	589_F	0.654	1.00
172_T	182_D	0.654	1.00
528_I	552_N	0.647	1.00
361_Q	387_H	0.645	1.00
470_G	539_F	0.645	1.00
64_V	69_D	0.644	1.00
248_N	285_W	0.643	1.00
131_E	161_G	0.643	1.00
545_L	549_Y	0.643	1.00
457_L	461_Y	0.642	1.00
628_K	631_A	0.642	1.00
275_Q	279_V	0.641	1.00
94_L	482_V	0.640	1.00
31_E	34_V	0.640	1.00
101_I	155_I	0.637	1.00
588_S	591_V	0.637	1.00
585_E	621_W	0.636	1.00
532_E	550_T	0.635	1.00
570_F	598_Q	0.635	1.00
321_Y	324_P	0.634	1.00
139_P	417_A	0.633	1.00
281_H	285_W	0.633	1.00
233_S	261_D	0.632	1.00
209_K	235_R	0.632	1.00
463_G	470_G	0.631	1.00
190_T	193_P	0.629	1.00
171_D	630_R	0.629	1.00
552_N	572_T	0.628	1.00
98_Y	450_E	0.628	1.00
170_V	173_T	0.628	1.00
486_I	522_N	0.628	1.00
77_V	89_V	0.627	1.00
378_L	382_V	0.626	1.00
533_T	549_Y	0.626	1.00
314_S	341_D	0.626	1.00
159_K	254_G	0.625	1.00
58_D	62_K	0.624	1.00
158_K	189_F	0.624	1.00
162_Q	244_T	0.624	1.00
615_W	633_V	0.623	1.00
365_F	383_R	0.623	1.00
232_F	260_Q	0.622	1.00
199_L	239_V	0.622	1.00
330_Q	337_E	0.620	1.00
422_S	447_L	0.620	1.00
137_R	534_E	0.620	1.00
422_S	426_L	0.619	1.00
164_W	167_T	0.617	1.00
380_T	384_M	0.617	1.00
242_A	245_P	0.617	1.00
48_P	379_T	0.616	1.00
163_K	193_P	0.615	1.00
317_V	320_K	0.614	1.00
318_D	321_Y	0.612	1.00
36_T	39_S	0.612	1.00
17_I	21_W	0.611	1.00
572_T	596_T	0.610	1.00
316_T	321_Y	0.610	1.00
447_L	486_I	0.608	1.00
554_G	568_L	0.608	1.00
175_Q	210_R	0.607	1.00
330_Q	333_T	0.607	1.00
411_K	474_S	0.606	1.00
554_G	565_L	0.605	1.00
174_I	655_Y	0.605	1.00
318_D	339_R	0.605	1.00
331_F	334_V	0.604	1.00
23_V	26_V	0.604	1.00
278_S	295_Y	0.603	1.00
322_T	325_L	0.603	1.00
359_A	420_A	0.601	1.00
393_H	418_F	0.600	1.00
45_K	462_M	0.599	1.00
543_W	551_Y	0.598	1.00
190_T	201_M	0.598	1.00
377_A	380_T	0.597	1.00
613_T	637_G	0.597	1.00
70_V	127_V	0.595	1.00
589_F	593_G	0.595	1.00
295_Y	318_D	0.594	1.00
138_G	456_E	0.594	1.00
597_G	613_T	0.594	1.00
575_G	613_T	0.593	1.00
188_F	205_G	0.593	1.00
234_S	260_Q	0.591	1.00
162_Q	193_P	0.590	1.00
326_T	331_F	0.590	1.00
183_T	208_A	0.589	1.00
472_E	475_V	0.588	1.00
94_L	98_Y	0.587	1.00
75_P	137_R	0.587	1.00
193_P	197_G	0.586	1.00
69_D	634_L	0.586	1.00
328_I	333_T	0.583	1.00
424_L	427_S	0.581	1.00
94_L	480_N	0.581	1.00
486_I	520_Y	0.581	1.00
543_W	547_I	0.580	1.00
335_G	339_R	0.579	1.00
323_L	334_V	0.579	1.00
545_L	551_Y	0.577	1.00
324_P	333_T	0.577	1.00
538_P	542_E	0.577	1.00
569_P	596_T	0.577	1.00
591_V	636_L	0.576	1.00
593_G	637_G	0.575	1.00
67_L	130_I	0.575	1.00
101_I	122_L	0.573	1.00
407_T	463_G	0.573	1.00
160_I	202_K	0.572	1.00
198_V	246_N	0.571	1.00
50_S	137_R	0.570	1.00
289_T	292_L	0.568	1.00
136_V	140_M	0.567	1.00
172_T	186_G	0.566	1.00
314_S	320_K	0.565	1.00
61_R	580_K	0.565	1.00
315_N	325_L	0.563	1.00
408_V	463_G	0.563	1.00
159_K	250_D	0.562	1.00
317_V	323_L	0.562	1.00
332_L	336_G	0.562	1.00
484_D	522_N	0.562	1.00
371_R	403_N	0.561	1.00
248_N	286_D	0.561	1.00
448_K	451_T	0.561	1.00
459_L	473_S	0.561	1.00
539_F	542_E	0.560	1.00
319_G	325_L	0.559	1.00
91_I	99_T	0.558	1.00
198_V	247_Q	0.557	1.00
325_L	328_I	0.556	1.00
413_G	456_E	0.556	1.00
367_E	381_G	0.556	1.00
94_L	528_I	0.555	1.00
172_T	657_M	0.555	1.00
160_I	201_M	0.551	1.00
283_G	290_S	0.550	1.00
175_Q	182_D	0.549	1.00
128_D	204_Y	0.548	1.00
99_T	150_G	0.548	1.00
17_I	23_V	0.548	1.00
317_V	338_W	0.548	1.00
418_F	451_T	0.548	1.00
156_I	159_K	0.548	1.00
277_Y	281_H	0.547	1.00
142_S	367_E	0.547	1.00
657_M	660_D	0.547	1.00
600_R	605_T	0.547	1.00
169_T	185_N	0.547	1.00
599_K	609_P	0.546	1.00
455_W	477_V	0.545	1.00
316_T	325_L	0.544	1.00
45_K	409_T	0.544	1.00
404_A	407_T	0.542	1.00
387_H	390_Y	0.541	1.00
20_A	24_L	0.541	1.00
164_W	170_V	0.540	1.00
534_E	548_N	0.539	1.00
161_G	200_G	0.538	1.00
574_N	592_S	0.536	1.00
25_A	28_D	0.535	1.00
183_T	191_S	0.535	1.00
249_H	253_A	0.535	1.00
210_R	232_F	0.534	1.00
339_R	361_Q	0.534	1.00
143_L	365_F	0.533	1.00
126_P	185_N	0.532	1.00
655_Y	659_V	0.531	1.00
605_T	609_P	0.528	1.00
617_T	631_A	0.527	1.00
129_S	236_D	0.527	1.00
254_G	280_S	0.526	1.00
58_D	546_S	0.525	1.00
45_K	403_N	0.525	1.00
398_A	402_Y	0.525	1.00
126_P	187_Q	0.524	1.00
239_V	242_A	0.524	1.00
322_T	331_F	0.524	1.00
322_T	333_T	0.523	1.00
614_I	638_D	0.523	1.00
327_A	335_G	0.523	1.00
292_L	296_G	0.522	1.00
293_K	320_K	0.522	1.00
287_Y	325_L	0.522	1.00
575_G	593_G	0.522	1.00
572_T	594_H	0.521	1.00
413_G	454_S	0.521	1.00
284_R	288_G	0.521	1.00
418_F	449_P	0.521	1.00
417_A	454_S	0.520	1.00
456_E	532_E	0.520	1.00
402_Y	405_T	0.519	1.00
577_L	589_F	0.519	1.00
72_K	616_N	0.518	1.00
90_S	98_Y	0.518	1.00
320_K	337_E	0.518	1.00
491_T	519_S	0.518	1.00
586_D	623_V	0.518	1.00
70_V	74_V	0.518	1.00
619_A	631_A	0.517	1.00
337_E	340_H	0.517	1.00
426_L	430_W	0.516	1.00
606_A	609_P	0.515	1.00
619_A	623_V	0.515	1.00
322_T	326_T	0.515	1.00
554_G	564_P	0.515	1.00
450_E	484_D	0.514	1.00
252_T	291_E	0.512	1.00
470_G	540_N	0.512	1.00
211_E	231_G	0.512	1.00
574_N	594_H	0.512	1.00
333_T	336_G	0.512	1.00
45_K	406_D	0.512	1.00
397_R	415_A	0.511	1.00
16_A	23_V	0.511	1.00
341_D	359_A	0.511	1.00
328_I	332_L	0.511	1.00
278_S	293_K	0.510	1.00
527_R	553_D	0.509	1.00
359_A	387_H	0.508	1.00
319_G	338_W	0.507	1.00
88_G	98_Y	0.507	1.00
453_E	479_R	0.506	1.00
149_L	419_K	0.506	1.00
49_A	397_R	0.505	1.00
539_F	543_W	0.505	1.00
108_V	276_N	0.505	1.00
623_V	626_D	0.504	1.00
370_W	378_L	0.503	1.00
547_I	551_Y	0.503	1.00
444_S	521_Y	0.503	1.00
330_Q	371_R	0.502	1.00
555_R	562_N	0.502	1.00
422_S	428_P	0.502	1.00
380_T	400_L	0.502	1.00
577_L	593_G	0.502	1.00
166_G	174_I	0.501	1.00
447_L	522_N	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2hdiA	1	0.902	100	0.185	Contact Map
3qlbA	1	0.8296	100	0.228	Contact Map
3efmA	1	0.8235	100	0.228	Contact Map
1xkwA	1	0.8477	100	0.23	Contact Map
2gufA	1	0.8115	100	0.245	Contact Map
4cu4A	1	0.8627	100	0.25	Contact Map
1kmoA	1	0.8567	100	0.251	Contact Map
2w16A	1	0.9035	100	0.252	Contact Map
3v8xA	1	0.8748	100	0.253	Contact Map
4b7oA	1	0.8597	100	0.258	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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