GLMS - ECOLI - GREMLIN Contacts

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GLMS - Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

UniProt:	P17169	Sequences: MCGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMTRLRRLGKVQMLAQAAEEHPLHGGTGIAHTRWATHGEPSEVNAHPHVSEHIVVVHNGIIENHEPLREELKARGYTFVSETDTEVIAHLVNWELKQGGTLREAVLRAIPQLRGAYGTVIMDSRHPDTLLAARSGSPLVIGLGMGENFIASDQLALLPVTRRFIFLEEGDIAEITRRSVNIFDKTGAEVKRQDIESNLQYDAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILACGTSYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLSRLKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRGDQYPIALEGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRARGGQLYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRNLAKSVTVE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10382
Length:	609 (606)
Sequences:	3826 (2113)
Seq/√Len:	85.8

ECOLI - GLMS
BACSU - GLMS
HALSA - GLMS
SULSO - Q980D3 Q97YQ6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
111_E	152_Q	4.858	1.00
115_R	134_W	4.391	1.00
294_E	341_N	4.021	1.00
373_A	386_S	3.901	1.00
224_D	228_A	3.853	1.00
264_I	445_I	3.825	1.00
22_R	56_A	3.661	1.00
298_I	308_G	3.483	1.00
146_V	171_L	3.374	1.00
141_T	144_E	3.187	1.00
128_I	153_L	3.158	1.00
211_D	232_R	3.127	1.00
361_R	385_E	3.080	1.00
17_L	69_G	3.052	1.00
132_V	149_A	3.048	1.00
402_S	405_A	3.041	1.00
262_N	266_N	3.007	1.00
51_K	598_Q	2.980	1.00
446_E	450_S	2.900	1.00
452_D	587_H	2.817	1.00
203_R	236_E	2.702	1.00
264_I	411_T	2.695	1.00
48_R	58_A	2.661	1.00
93_H	165_R	2.656	1.00
172_A	190_I	2.615	1.00
117_Y	133_N	2.583	1.00
143_R	223_F	2.581	1.00
166_H	169_T	2.552	1.00
546_V	559_N	2.519	1.00
169_T	214_E	2.484	1.00
172_A	213_A	2.470	1.00
221_N	229_E	2.435	1.00
92_E	133_N	2.408	1.00
181_I	213_A	2.399	1.00
117_Y	134_W	2.375	1.00
128_I	159_T	2.362	1.00
135_E	152_Q	2.346	1.00
445_I	579_V	2.324	1.00
92_E	117_Y	2.311	1.00
347_L	413_L	2.309	1.00
96_V	129_A	2.233	1.00
181_I	220_V	2.222	1.00
53_Q	57_Q	2.211	1.00
117_Y	130_H	2.208	1.00
294_E	339_R	2.198	1.00
142_L	171_L	2.197	1.00
84_V	122_E	2.188	1.00
48_R	83_E	2.182	1.00
418_A	434_I	2.158	1.00
183_L	205_I	2.147	1.00
538_R	560_M	2.138	1.00
258_Y	452_D	2.133	1.00
132_V	161_I	2.118	1.00
484_A	495_A	2.077	1.00
441_L	575_I	2.049	1.00
184_G	187_E	2.039	1.00
461_D	561_H	2.032	1.00
308_G	347_L	2.028	1.00
19_E	199_P	2.000	1.00
315_F	420_L	1.976	1.00
188_N	220_V	1.964	1.00
315_F	417_V	1.959	1.00
315_F	323_C	1.947	1.00
109_R	113_K	1.926	1.00
154_R	528_E	1.922	1.00
160_V	170_L	1.911	1.00
142_L	163_D	1.907	1.00
267_T	392_T	1.906	1.00
430_I	433_D	1.902	1.00
590_L	596_V	1.891	1.00
422_R	431_E	1.890	1.00
327_I	499_A	1.881	1.00
551_D	564_E	1.880	1.00
519_V	534_I	1.878	1.00
96_V	125_T	1.877	1.00
143_R	214_E	1.833	1.00
160_V	190_I	1.822	1.00
203_R	234_D	1.818	1.00
135_E	148_R	1.818	1.00
500_A	530_L	1.818	1.00
150_I	153_L	1.815	1.00
93_H	164_S	1.794	1.00
58_A	83_E	1.793	1.00
406_F	479_I	1.793	1.00
146_V	161_I	1.789	1.00
295_H	324_D	1.786	1.00
346_T	360_L	1.782	1.00
481_L	497_A	1.774	1.00
54_M	57_Q	1.770	1.00
183_L	220_V	1.765	1.00
208_E	232_R	1.763	1.00
518_I	584_L	1.763	1.00
326_E	334_R	1.761	1.00
91_S	117_Y	1.758	1.00
463_S	591_I	1.748	1.00
49_L	82_S	1.742	1.00
362_L	365_E	1.737	1.00
448_M	576_F	1.729	1.00
47_R	83_E	1.729	1.00
168_D	217_R	1.728	1.00
132_V	146_V	1.722	1.00
36_V	66_G	1.720	1.00
338_V	368_Y	1.710	1.00
90_V	95_V	1.699	1.00
135_E	149_A	1.675	1.00
483_G	581_L	1.660	1.00
371_S	386_S	1.657	1.00
11_R	187_E	1.652	1.00
427_D	430_I	1.647	1.00
303_T	402_S	1.640	1.00
214_E	221_N	1.637	1.00
437_G	444_R	1.637	1.00
183_L	188_N	1.636	1.00
144_E	147_L	1.628	1.00
222_I	232_R	1.624	1.00
293_V	343_L	1.620	1.00
8_I	217_R	1.613	1.00
447_Q	550_Q	1.613	1.00
317_S	335_K	1.612	1.00
43_M	95_V	1.610	1.00
339_R	342_S	1.604	1.00
188_N	219_S	1.598	1.00
565_M	577_Y	1.596	1.00
460_E	591_I	1.594	1.00
17_L	71_A	1.591	1.00
202_R	236_E	1.585	1.00
305_Y	309_M	1.580	1.00
8_I	68_T	1.572	1.00
263_A	408_T	1.571	1.00
94_I	163_D	1.570	1.00
344_M	368_Y	1.569	1.00
437_G	569_E	1.563	1.00
51_K	595_D	1.563	1.00
551_D	567_H	1.561	1.00
169_T	216_T	1.558	1.00
110_E	114_A	1.552	1.00
548_A	564_E	1.538	1.00
375_C	383_V	1.535	1.00
18_L	34_L	1.532	1.00
447_Q	450_S	1.529	1.00
320_G	335_K	1.527	1.00
14_A	34_L	1.519	1.00
149_A	153_L	1.517	1.00
172_A	181_I	1.505	1.00
587_H	591_I	1.505	1.00
249_Y	258_Y	1.503	1.00
94_I	136_L	1.499	0.99
96_V	128_I	1.493	0.99
216_T	219_S	1.480	0.99
91_S	133_N	1.475	0.99
392_T	408_T	1.471	0.99
320_G	337_A	1.459	0.99
35_A	95_V	1.456	0.99
348_S	382_L	1.454	0.99
453_K	456_E	1.448	0.99
107_P	154_R	1.438	0.99
419_K	423_L	1.437	0.99
440_A	444_R	1.436	0.99
251_H	586_Y	1.432	0.99
46_L	58_A	1.431	0.99
205_I	220_V	1.422	0.99
105_H	109_R	1.412	0.99
296_I	345_I	1.409	0.99
548_A	555_V	1.408	0.99
19_E	22_R	1.403	0.99
471_L	537_V	1.396	0.99
318_L	571_V	1.396	0.99
331_F	338_V	1.385	0.99
53_Q	56_A	1.385	0.99
378_P	391_M	1.381	0.99
462_F	561_H	1.380	0.99
477_Y	481_L	1.375	0.99
150_I	173_A	1.369	0.99
94_I	142_L	1.362	0.99
194_Q	206_F	1.360	0.99
175_S	210_G	1.360	0.99
471_L	519_V	1.351	0.99
9_A	13_V	1.325	0.99
205_I	222_I	1.324	0.99
143_R	147_L	1.321	0.99
147_L	223_F	1.319	0.99
444_R	568_V	1.309	0.99
38_D	42_H	1.307	0.99
35_A	43_M	1.306	0.99
109_R	119_F	1.306	0.99
357_L	361_R	1.304	0.99
534_I	544_L	1.303	0.99
145_A	149_A	1.302	0.99
364_K	387_D	1.300	0.99
250_R	590_L	1.298	0.99
433_D	569_E	1.296	0.99
548_A	562_I	1.295	0.99
110_E	113_K	1.294	0.98
383_V	389_A	1.288	0.98
49_L	81_P	1.281	0.98
418_A	431_E	1.272	0.98
312_R	324_D	1.267	0.98
265_K	446_E	1.264	0.98
479_I	578_T	1.254	0.98
421_S	426_L	1.248	0.98
314_W	414_L	1.247	0.98
462_F	584_L	1.245	0.98
161_I	171_L	1.240	0.98
556_S	564_E	1.239	0.98
297_Q	331_F	1.226	0.98
214_E	223_F	1.214	0.98
354_A	358_A	1.208	0.98
589_A	594_T	1.204	0.98
37_V	162_M	1.201	0.98
207_L	213_A	1.199	0.98
451_Q	454_R	1.191	0.97
7_A	13_V	1.190	0.97
547_F	565_M	1.189	0.97
163_D	166_H	1.179	0.97
452_D	456_E	1.179	0.97
374_I	413_L	1.178	0.97
139_G	144_E	1.175	0.97
223_F	229_E	1.173	0.97
344_M	363_S	1.172	0.97
443_S	446_E	1.171	0.97
239_L	244_G	1.170	0.97
93_H	133_N	1.169	0.97
18_L	56_A	1.162	0.97
111_E	134_W	1.162	0.97
267_T	412_V	1.160	0.97
143_R	212_I	1.160	0.97
373_A	382_L	1.157	0.97
119_F	127_V	1.155	0.97
342_S	368_Y	1.153	0.97
42_H	164_S	1.152	0.97
254_Q	258_Y	1.146	0.97
35_A	45_R	1.144	0.97
296_I	343_L	1.144	0.97
360_L	382_L	1.139	0.97
458_L	545_Y	1.139	0.97
92_E	130_H	1.139	0.97
568_V	576_F	1.134	0.97
511_I	542_G	1.132	0.96
135_E	138_Q	1.131	0.96
134_W	138_Q	1.128	0.96
311_S	413_L	1.121	0.96
184_G	188_N	1.120	0.96
527_L	552_A	1.118	0.96
183_L	234_D	1.111	0.96
296_I	321_I	1.109	0.96
390_L	412_V	1.108	0.96
444_R	576_F	1.102	0.96
332_R	358_A	1.099	0.96
448_M	451_Q	1.094	0.96
68_T	170_L	1.093	0.96
37_V	68_T	1.093	0.96
49_L	54_M	1.092	0.96
295_H	339_R	1.088	0.96
522_P	577_Y	1.085	0.96
142_L	146_V	1.084	0.95
461_D	543_Q	1.082	0.95
106_E	110_E	1.080	0.95
471_L	503_L	1.078	0.95
148_R	151_P	1.078	0.95
136_L	165_R	1.077	0.95
584_L	588_V	1.072	0.95
318_L	417_V	1.068	0.95
466_H	592_K	1.068	0.95
524_N	570_E	1.068	0.95
157_Y	175_S	1.062	0.95
346_T	371_S	1.061	0.95
474_G	526_L	1.061	0.95
144_E	148_R	1.057	0.95
430_I	434_I	1.057	0.95
517_V	542_G	1.057	0.95
139_G	148_R	1.056	0.95
306_N	309_M	1.056	0.95
345_I	416_L	1.055	0.95
182_G	201_T	1.053	0.95
392_T	409_Q	1.052	0.95
260_Q	407_T	1.052	0.95
93_H	163_D	1.050	0.95
246_K	598_Q	1.048	0.95
468_A	518_I	1.047	0.95
456_E	460_E	1.040	0.94
457_A	460_E	1.039	0.94
133_N	137_K	1.034	0.94
370_G	387_D	1.032	0.94
160_V	172_A	1.030	0.94
171_L	214_E	1.030	0.94
10_Q	217_R	1.028	0.94
109_R	127_V	1.027	0.94
46_L	63_P	1.027	0.94
49_L	80_E	1.023	0.94
426_L	431_E	1.015	0.94
521_A	527_L	1.013	0.94
272_I	439_Q	1.009	0.93
535_E	538_R	1.007	0.93
14_A	66_G	1.006	0.93
38_D	41_G	1.005	0.93
583_L	587_H	1.004	0.93
136_L	163_D	1.003	0.93
132_V	145_A	1.002	0.93
441_L	576_F	1.001	0.93
316_E	334_R	1.000	0.93
346_T	386_S	0.999	0.93
188_N	218_R	0.999	0.93
12_D	67_G	0.989	0.93
459_A	584_L	0.987	0.93
206_F	235_I	0.986	0.93
250_R	254_Q	0.983	0.92
595_D	598_Q	0.981	0.92
548_A	552_A	0.981	0.92
111_E	115_R	0.978	0.92
454_R	457_A	0.976	0.92
254_Q	452_D	0.974	0.92
160_V	215_I	0.974	0.92
273_S	276_Q	0.971	0.92
362_L	366_L	0.970	0.92
251_H	254_Q	0.969	0.92
147_L	212_I	0.965	0.92
271_R	415_M	0.964	0.92
430_I	569_E	0.962	0.92
346_T	363_S	0.962	0.92
311_S	315_F	0.961	0.92
550_Q	564_E	0.961	0.92
549_D	567_H	0.961	0.92
406_F	478_P	0.961	0.92
80_E	541_G	0.960	0.92
190_I	215_I	0.960	0.92
295_H	322_P	0.958	0.92
370_G	388_L	0.958	0.92
112_L	119_F	0.954	0.91
445_I	575_I	0.953	0.91
235_I	379_G	0.950	0.91
277_V	280_S	0.948	0.91
451_Q	563_I	0.947	0.91
319_A	417_V	0.944	0.91
11_R	189_F	0.944	0.91
553_G	556_S	0.944	0.91
306_N	481_L	0.944	0.91
6_G	190_I	0.943	0.91
279_L	390_L	0.941	0.91
321_I	424_K	0.936	0.91
310_V	479_I	0.936	0.91
142_L	161_I	0.935	0.90
319_A	424_K	0.931	0.90
476_Q	520_V	0.930	0.90
47_R	90_V	0.929	0.90
419_K	422_R	0.927	0.90
195_L	198_L	0.925	0.90
22_R	52_V	0.925	0.90
136_L	139_G	0.921	0.90
296_I	323_C	0.918	0.90
543_Q	560_M	0.918	0.90
23_R	199_P	0.918	0.90
411_T	575_I	0.917	0.90
503_L	508_L	0.917	0.90
537_V	544_L	0.914	0.89
113_K	118_T	0.913	0.89
437_G	440_A	0.912	0.89
467_H	515_M	0.911	0.89
297_Q	342_S	0.911	0.89
135_E	145_A	0.911	0.89
38_D	44_T	0.909	0.89
537_V	542_G	0.909	0.89
469_L	515_M	0.908	0.89
156_A	176_G	0.908	0.89
174_R	361_R	0.907	0.89
421_S	431_E	0.904	0.89
80_E	122_E	0.903	0.89
162_M	170_L	0.903	0.89
68_T	168_D	0.899	0.89
394_A	408_T	0.898	0.89
357_L	381_S	0.895	0.88
174_R	209_E	0.895	0.88
185_M	203_R	0.895	0.88
205_I	234_D	0.894	0.88
14_A	36_V	0.893	0.88
292_K	341_N	0.893	0.88
520_V	581_L	0.890	0.88
213_A	220_V	0.890	0.88
201_T	236_E	0.888	0.88
130_H	133_N	0.888	0.88
293_V	370_G	0.887	0.88
268_L	438_L	0.885	0.88
95_V	162_M	0.885	0.88
122_E	535_E	0.884	0.88
295_H	342_S	0.882	0.88
45_R	90_V	0.880	0.88
470_F	487_L	0.880	0.88
128_I	149_A	0.879	0.88
383_V	391_M	0.879	0.88
49_L	83_E	0.879	0.88
415_M	435_V	0.878	0.88
84_V	120_V	0.877	0.87
315_F	416_L	0.870	0.87
285_N	288_E	0.868	0.87
51_K	246_K	0.867	0.87
187_E	201_T	0.866	0.87
466_H	512_D	0.866	0.87
274_H	439_Q	0.864	0.87
258_Y	449_L	0.864	0.87
103_E	529_K	0.862	0.87
8_I	168_D	0.860	0.86
298_I	323_C	0.859	0.86
251_H	590_L	0.858	0.86
478_P	507_P	0.858	0.86
467_H	494_H	0.858	0.86
300_A	304_S	0.855	0.86
48_R	54_M	0.854	0.86
138_Q	141_T	0.853	0.86
399_G	405_A	0.852	0.86
245_D	252_Y	0.852	0.86
52_V	71_A	0.848	0.86
12_D	15_E	0.846	0.86
433_D	437_G	0.842	0.85
543_Q	561_H	0.836	0.85
533_N	536_E	0.835	0.85
143_R	221_N	0.834	0.85
52_V	59_A	0.834	0.85
16_I	200_V	0.833	0.85
18_L	59_A	0.832	0.85
120_V	130_H	0.831	0.84
550_Q	567_H	0.831	0.84
451_Q	455_I	0.830	0.84
56_A	60_E	0.828	0.84
294_E	342_S	0.827	0.84
194_Q	198_L	0.825	0.84
11_R	16_I	0.822	0.84
94_I	129_A	0.820	0.84
470_F	581_L	0.820	0.84
525_E	570_E	0.820	0.84
159_T	173_A	0.817	0.83
374_I	416_L	0.817	0.83
576_F	580_P	0.816	0.83
529_K	609_E	0.816	0.83
157_Y	225_K	0.815	0.83
130_H	134_W	0.810	0.83
191_A	196_A	0.808	0.83
253_M	399_G	0.808	0.83
181_I	207_L	0.807	0.83
336_S	362_L	0.807	0.83
399_G	507_P	0.807	0.83
222_I	230_V	0.807	0.83
190_I	213_A	0.806	0.83
36_V	64_L	0.806	0.83
298_I	413_L	0.805	0.83
437_G	572_I	0.804	0.82
478_P	497_A	0.802	0.82
428_A	432_H	0.802	0.82
46_L	62_H	0.800	0.82
290_L	420_L	0.798	0.82
535_E	558_D	0.797	0.82
36_V	69_G	0.797	0.82
511_I	517_V	0.796	0.82
298_I	325_V	0.795	0.82
119_F	131_L	0.795	0.82
487_L	493_I	0.795	0.82
456_E	587_H	0.795	0.82
279_L	282_L	0.792	0.82
128_I	150_I	0.791	0.81
47_R	84_V	0.789	0.81
407_T	579_V	0.785	0.81
237_S	379_G	0.784	0.81
320_G	336_S	0.782	0.81
299_L	331_F	0.780	0.81
406_F	578_T	0.779	0.80
399_G	406_F	0.778	0.80
440_A	443_S	0.778	0.80
393_N	396_T	0.777	0.80
92_E	118_T	0.773	0.80
262_N	446_E	0.773	0.80
188_N	215_I	0.771	0.80
312_R	316_E	0.771	0.80
328_A	537_V	0.771	0.80
7_A	16_I	0.771	0.80
309_M	325_V	0.767	0.79
462_F	468_A	0.766	0.79
468_A	487_L	0.765	0.79
360_L	386_S	0.765	0.79
293_V	342_S	0.764	0.79
305_Y	327_I	0.764	0.79
434_I	572_I	0.764	0.79
141_T	169_T	0.763	0.79
309_M	481_L	0.763	0.79
299_L	344_M	0.761	0.79
575_I	580_P	0.761	0.79
487_L	491_S	0.760	0.79
303_T	307_S	0.759	0.79
57_Q	61_E	0.757	0.79
444_R	448_M	0.756	0.78
163_D	171_L	0.756	0.78
172_A	207_L	0.752	0.78
68_T	162_M	0.751	0.78
92_E	134_W	0.750	0.78
264_I	392_T	0.750	0.78
249_Y	254_Q	0.749	0.78
471_L	480_A	0.749	0.78
343_L	372_L	0.749	0.78
288_E	370_G	0.747	0.78
254_Q	586_Y	0.747	0.78
476_Q	573_A	0.744	0.77
436_H	440_A	0.743	0.77
43_M	90_V	0.737	0.77
378_P	383_V	0.737	0.77
484_A	497_A	0.737	0.77
140_G	148_R	0.737	0.77
335_K	366_L	0.734	0.76
410_L	575_I	0.732	0.76
138_Q	148_R	0.732	0.76
57_Q	60_E	0.730	0.76
588_V	592_K	0.730	0.76
267_T	408_T	0.729	0.76
181_I	205_I	0.727	0.76
378_P	389_A	0.726	0.76
277_V	415_M	0.726	0.76
112_L	131_L	0.726	0.76
212_I	223_F	0.725	0.75
311_S	417_V	0.725	0.75
198_L	239_L	0.722	0.75
519_V	530_L	0.721	0.75
141_T	166_H	0.721	0.75
254_Q	587_H	0.721	0.75
186_G	218_R	0.721	0.75
93_H	136_L	0.721	0.75
112_L	116_G	0.719	0.75
373_A	389_A	0.718	0.75
548_A	551_D	0.717	0.75
559_N	562_I	0.717	0.75
197_L	204_F	0.716	0.75
455_I	583_L	0.714	0.74
168_D	216_T	0.714	0.74
170_L	190_I	0.714	0.74
208_E	211_D	0.709	0.74
136_L	145_A	0.708	0.74
277_V	281_E	0.708	0.74
483_G	578_T	0.708	0.74
426_L	430_I	0.708	0.74
237_S	244_G	0.706	0.74
207_L	211_D	0.706	0.74
291_S	423_L	0.706	0.74
148_R	152_Q	0.704	0.73
80_E	84_V	0.704	0.73
434_I	437_G	0.704	0.73
169_T	172_A	0.704	0.73
111_E	114_A	0.703	0.73
498_Y	507_P	0.702	0.73
263_A	267_T	0.701	0.73
483_G	490_I	0.700	0.73
314_W	417_V	0.699	0.73
462_F	588_V	0.697	0.73
407_T	575_I	0.697	0.73
8_I	215_I	0.695	0.72
422_R	428_A	0.694	0.72
332_R	529_K	0.694	0.72
307_S	413_L	0.693	0.72
364_K	385_E	0.693	0.72
469_L	512_D	0.693	0.72
314_W	410_L	0.692	0.72
346_T	356_T	0.691	0.72
181_I	222_I	0.691	0.72
455_I	584_L	0.690	0.72
211_D	224_D	0.690	0.72
338_V	342_S	0.689	0.72
254_Q	583_L	0.689	0.72
59_A	63_P	0.689	0.72
320_G	323_C	0.688	0.72
94_I	165_R	0.688	0.72
410_L	414_L	0.688	0.72
154_R	175_S	0.687	0.72
589_A	596_V	0.686	0.71
436_H	439_Q	0.685	0.71
298_I	345_I	0.685	0.71
136_L	141_T	0.684	0.71
503_L	537_V	0.684	0.71
275_G	432_H	0.684	0.71
465_K	543_Q	0.684	0.71
468_A	588_V	0.684	0.71
402_S	509_A	0.684	0.71
513_A	541_G	0.683	0.71
47_R	120_V	0.683	0.71
417_V	421_S	0.681	0.71
202_R	240_Q	0.681	0.71
45_R	95_V	0.680	0.71
416_L	420_L	0.679	0.71
239_L	379_G	0.679	0.71
15_E	56_A	0.679	0.71
512_D	542_G	0.677	0.70
435_V	439_Q	0.676	0.70
303_T	509_A	0.671	0.70
456_E	591_I	0.670	0.70
263_A	394_A	0.670	0.70
422_R	426_L	0.668	0.69
32_A	55_L	0.667	0.69
6_G	160_V	0.666	0.69
462_F	518_I	0.666	0.69
458_L	462_F	0.665	0.69
361_R	381_S	0.665	0.69
327_I	501_G	0.664	0.69
7_A	187_E	0.664	0.69
143_R	171_L	0.663	0.69
198_L	201_T	0.662	0.69
275_G	439_Q	0.661	0.69
480_A	520_V	0.661	0.69
268_L	411_T	0.661	0.69
199_P	202_R	0.659	0.68
136_L	140_G	0.658	0.68
374_I	392_T	0.658	0.68
97_V	180_V	0.658	0.68
311_S	314_W	0.658	0.68
405_A	605_S	0.657	0.68
12_D	65_H	0.657	0.68
139_G	145_A	0.655	0.68
39_A	42_H	0.654	0.68
568_V	572_I	0.654	0.68
48_R	52_V	0.653	0.68
470_F	500_A	0.652	0.68
363_S	368_Y	0.652	0.68
312_R	325_V	0.651	0.67
1_M	4_I	0.650	0.67
177_S	354_A	0.645	0.67
521_A	534_I	0.645	0.67
470_F	585_A	0.641	0.66
544_L	559_N	0.640	0.66
101_I	532_S	0.639	0.66
90_V	130_H	0.639	0.66
468_A	495_A	0.639	0.66
390_L	416_L	0.638	0.66
266_N	392_T	0.637	0.66
206_F	399_G	0.637	0.66
469_L	596_V	0.637	0.66
14_A	64_L	0.636	0.66
180_V	194_Q	0.636	0.66
67_G	217_R	0.636	0.66
418_A	421_S	0.635	0.66
306_N	375_C	0.635	0.66
382_L	391_M	0.634	0.65
523_N	527_L	0.633	0.65
94_I	145_A	0.632	0.65
431_E	435_V	0.632	0.65
546_V	562_I	0.631	0.65
407_T	578_T	0.630	0.65
455_I	580_P	0.630	0.65
467_H	498_Y	0.630	0.65
561_H	564_E	0.629	0.65
448_M	455_I	0.629	0.65
253_M	490_I	0.628	0.65
270_G	393_N	0.627	0.65
315_F	319_A	0.627	0.65
96_V	159_T	0.627	0.65
459_A	591_I	0.626	0.64
327_I	503_L	0.625	0.64
180_V	197_L	0.625	0.64
304_S	347_L	0.624	0.64
346_T	373_A	0.624	0.64
21_L	32_A	0.624	0.64
180_V	357_L	0.623	0.64
554_F	557_S	0.623	0.64
381_S	385_E	0.622	0.64
175_S	225_K	0.621	0.64
280_S	283_G	0.620	0.64
478_P	481_L	0.620	0.64
154_R	279_L	0.619	0.64
304_S	503_L	0.619	0.64
189_F	200_V	0.617	0.63
272_I	435_V	0.616	0.63
13_V	16_I	0.615	0.63
555_V	564_E	0.614	0.63
345_I	372_L	0.613	0.63
279_L	286_A	0.611	0.63
147_L	227_G	0.610	0.62
239_L	378_P	0.609	0.62
134_W	137_K	0.609	0.62
290_L	293_V	0.608	0.62
304_S	375_C	0.606	0.62
198_L	202_R	0.606	0.62
186_G	189_F	0.606	0.62
128_I	161_I	0.606	0.62
448_M	563_I	0.604	0.62
414_L	434_I	0.603	0.62
310_V	574_P	0.601	0.61
209_E	361_R	0.601	0.61
15_E	19_E	0.600	0.61
437_G	441_L	0.600	0.61
444_R	447_Q	0.600	0.61
406_F	507_P	0.599	0.61
147_L	151_P	0.599	0.61
249_Y	452_D	0.599	0.61
98_H	177_S	0.597	0.61
411_T	441_L	0.595	0.60
183_L	203_R	0.595	0.60
153_L	157_Y	0.594	0.60
166_H	171_L	0.594	0.60
288_E	292_K	0.594	0.60
406_F	476_Q	0.593	0.60
281_E	284_P	0.593	0.60
476_Q	577_Y	0.593	0.60
549_D	573_A	0.592	0.60
462_F	546_V	0.592	0.60
119_F	130_H	0.591	0.60
464_D	592_K	0.591	0.60
181_I	190_I	0.590	0.60
250_R	598_Q	0.590	0.60
282_L	290_L	0.590	0.60
264_I	448_M	0.588	0.60
273_S	278_D	0.588	0.60
491_S	594_T	0.586	0.59
276_Q	431_E	0.586	0.59
402_S	511_I	0.586	0.59
411_T	438_L	0.585	0.59
91_S	402_S	0.585	0.59
478_P	484_A	0.585	0.59
547_F	563_I	0.585	0.59
282_L	390_L	0.584	0.59
136_L	142_L	0.584	0.59
441_L	572_I	0.583	0.59
399_G	509_A	0.583	0.59
70_I	160_V	0.583	0.59
448_M	565_M	0.582	0.59
329_S	501_G	0.581	0.59
507_P	585_A	0.580	0.59
421_S	425_G	0.579	0.58
514_D	541_G	0.578	0.58
405_A	511_I	0.578	0.58
487_L	588_V	0.578	0.58
82_S	86_A	0.577	0.58
10_Q	186_G	0.577	0.58
206_F	383_V	0.576	0.58
555_V	559_N	0.576	0.58
23_R	245_D	0.576	0.58
201_T	234_D	0.575	0.58
103_E	358_A	0.575	0.58
6_G	367_G	0.574	0.58
431_E	434_I	0.574	0.58
278_D	281_E	0.573	0.58
271_R	393_N	0.572	0.58
524_N	567_H	0.572	0.58
21_L	71_A	0.572	0.58
211_D	230_V	0.572	0.58
216_T	220_V	0.571	0.57
546_V	555_V	0.570	0.57
34_L	71_A	0.569	0.57
13_V	17_L	0.568	0.57
333_Y	358_A	0.568	0.57
105_H	535_E	0.568	0.57
143_R	169_T	0.568	0.57
177_S	537_V	0.567	0.57
240_Q	243_A	0.567	0.57
92_E	137_K	0.566	0.57
398_I	598_Q	0.566	0.57
44_T	62_H	0.565	0.57
283_G	388_L	0.565	0.57
440_A	568_V	0.565	0.57
296_I	315_F	0.565	0.57
17_L	34_L	0.565	0.57
179_L	190_I	0.564	0.56
508_L	512_D	0.563	0.56
364_K	371_S	0.563	0.56
34_L	59_A	0.563	0.56
379_G	389_A	0.563	0.56
313_Y	478_P	0.563	0.56
292_K	340_R	0.560	0.56
382_L	386_S	0.560	0.56
106_E	109_R	0.560	0.56
379_G	383_V	0.559	0.56
469_L	511_I	0.559	0.56
151_P	225_K	0.559	0.56
409_Q	413_L	0.558	0.56
603_A	607_T	0.558	0.56
109_R	129_A	0.558	0.56
306_N	409_Q	0.557	0.56
523_N	549_D	0.557	0.56
309_M	474_G	0.557	0.56
283_G	286_A	0.557	0.56
476_Q	524_N	0.557	0.56
94_I	133_N	0.556	0.55
137_K	140_G	0.554	0.55
279_L	422_R	0.554	0.55
379_G	391_M	0.554	0.55
299_L	346_T	0.553	0.55
399_G	478_P	0.553	0.55
304_S	325_V	0.551	0.55
478_P	522_P	0.551	0.55
427_D	431_E	0.550	0.55
415_M	418_A	0.550	0.55
523_N	552_A	0.550	0.55
377_V	392_T	0.549	0.54
135_E	140_G	0.549	0.54
547_F	577_Y	0.548	0.54
484_A	509_A	0.547	0.54
468_A	493_I	0.547	0.54
42_H	118_T	0.547	0.54
375_C	542_G	0.547	0.54
176_G	209_E	0.546	0.54
83_E	86_A	0.546	0.54
517_V	537_V	0.546	0.54
576_F	579_V	0.546	0.54
529_K	532_S	0.545	0.54
131_L	153_L	0.544	0.54
463_S	588_V	0.544	0.54
146_V	149_A	0.544	0.54
476_Q	522_P	0.544	0.54
508_L	542_G	0.543	0.54
465_K	516_P	0.543	0.54
421_S	427_D	0.543	0.54
176_G	524_N	0.543	0.54
184_G	201_T	0.542	0.54
222_I	467_H	0.542	0.54
346_T	382_L	0.542	0.54
187_E	334_R	0.542	0.54
146_V	173_A	0.541	0.53
335_K	525_E	0.541	0.53
447_Q	451_Q	0.541	0.53
8_I	170_L	0.540	0.53
189_F	197_L	0.540	0.53
260_Q	579_V	0.539	0.53
299_L	558_D	0.539	0.53
97_V	290_L	0.539	0.53
194_Q	204_F	0.539	0.53
333_Y	532_S	0.538	0.53
12_D	38_D	0.538	0.53
507_P	520_V	0.538	0.53
32_A	50_G	0.537	0.53
108_L	153_L	0.536	0.53
534_I	546_V	0.536	0.53
599_P	604_K	0.535	0.53
90_V	120_V	0.533	0.52
179_L	207_L	0.533	0.52
508_L	511_I	0.532	0.52
520_V	577_Y	0.532	0.52
538_R	544_L	0.532	0.52
297_Q	324_D	0.532	0.52
246_K	368_Y	0.532	0.52
94_I	161_I	0.531	0.52
72_H	87_H	0.531	0.52
93_H	117_Y	0.530	0.52
534_I	559_N	0.529	0.52
521_A	530_L	0.529	0.52
284_P	287_D	0.529	0.52
311_S	434_I	0.528	0.52
16_I	189_F	0.528	0.52
8_I	169_T	0.527	0.52
538_R	559_N	0.527	0.52
538_R	558_D	0.527	0.52
371_S	387_D	0.526	0.51
6_G	490_I	0.526	0.51
299_L	363_S	0.526	0.51
26_Y	193_D	0.526	0.51
317_S	430_I	0.526	0.51
90_V	164_S	0.525	0.51
240_Q	379_G	0.523	0.51
132_V	159_T	0.523	0.51
402_S	542_G	0.523	0.51
13_V	69_G	0.522	0.51
91_S	112_L	0.522	0.51
448_M	566_P	0.522	0.51
271_R	391_M	0.522	0.51
478_P	495_A	0.522	0.51
49_L	159_T	0.521	0.51
251_H	594_T	0.521	0.51
77_T	89_H	0.520	0.51
495_A	522_P	0.520	0.51
454_R	561_H	0.519	0.50
113_K	122_E	0.519	0.50
408_T	411_T	0.519	0.50
524_N	549_D	0.518	0.50
216_T	221_N	0.518	0.50
547_F	581_L	0.517	0.50
316_E	325_V	0.517	0.50
414_L	572_I	0.516	0.50
455_I	563_I	0.516	0.50
130_H	135_E	0.515	0.50
574_P	580_P	0.513	0.50
476_Q	523_N	0.513	0.50
342_S	347_L	0.513	0.50
286_A	291_S	0.513	0.50
460_E	463_S	0.512	0.50
546_V	560_M	0.512	0.50
202_R	379_G	0.512	0.50
270_G	415_M	0.511	0.49
110_E	557_S	0.511	0.49
297_Q	339_R	0.511	0.49
66_G	69_G	0.510	0.49
260_Q	509_A	0.510	0.49
93_H	137_K	0.510	0.49
156_A	354_A	0.509	0.49
267_T	374_I	0.509	0.49
405_A	537_V	0.509	0.49
535_E	539_A	0.509	0.49
250_R	456_E	0.508	0.49
277_V	431_E	0.508	0.49
180_V	195_L	0.508	0.49
454_R	458_L	0.507	0.49
282_L	285_N	0.507	0.49
111_E	135_E	0.507	0.49
242_D	250_R	0.507	0.49
503_L	515_M	0.506	0.49
206_F	542_G	0.506	0.49
277_V	283_G	0.505	0.49
173_A	210_G	0.505	0.49
471_L	530_L	0.505	0.49
511_I	537_V	0.505	0.49
304_S	405_A	0.505	0.49
597_D	604_K	0.504	0.48
469_L	542_G	0.503	0.48
298_I	315_F	0.503	0.48
375_C	509_A	0.503	0.48
276_Q	422_R	0.503	0.48
468_A	515_M	0.503	0.48
193_D	605_S	0.502	0.48
578_T	581_L	0.502	0.48
360_L	371_S	0.501	0.48
238_N	241_Y	0.500	0.48

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
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HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4amvA	2	0.9967	100	0.314	Contact Map
2zj3A	2	0.5961	100	0.578	Contact Map
1moqA	2	0.5993	100	0.583	Contact Map
3tbfA	2	0.5846	100	0.585	Contact Map
2pocA	4	0.5731	100	0.589	Contact Map
4s1wA	2	0.5599	100	0.594	Contact Map
3knzA	2	0.5205	100	0.643	Contact Map
2amlA	2	0.5813	100	0.645	Contact Map
1j5xA	2	0.5189	100	0.648	Contact Map
3g68A	3	0.5599	100	0.65	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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