GREMLIN Database
SYP - Proline--tRNA ligase
UniProt: P16659 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10770
Length: 572 (560)
Sequences: 2233 (1290)
Seq/√Len: 54.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
254_L365_I6.7411.00
186_S192_F4.0661.00
256_D368_K3.5471.00
456_I465_I3.4071.00
57_V448_V3.2321.00
164_H169_S3.1691.00
164_H173_T2.9701.00
455_A471_I2.9251.00
227_S399_G2.9071.00
292_P346_P2.8751.00
171_Q416_Q2.8641.00
256_D367_G2.8551.00
82_E119_R2.8501.00
227_S396_S2.7741.00
495_K499_E2.7191.00
224_S227_S2.7141.00
97_V103_P2.7131.00
487_F491_E2.6911.00
179_A183_K2.6771.00
62_N133_Y2.6631.00
77_A81_Q2.6551.00
51_K54_E2.6051.00
59_E187_R2.5961.00
224_S399_G2.5621.00
396_S399_G2.5131.00
63_N183_K2.4241.00
6_Y67_I2.3661.00
419_T423_E2.3521.00
543_D556_L2.3181.00
253_T371_F2.3101.00
390_V403_L2.2961.00
463_R521_A2.2921.00
14_T24_Q2.2801.00
264_A268_E2.2701.00
224_S396_S2.2671.00
2_R494_E2.2631.00
280_T295_A2.2581.00
52_K506_E2.2201.00
555_Q565_Y2.1501.00
358_D372_G2.1461.00
69_V114_I2.1271.00
254_L368_K2.1271.00
171_Q175_D2.1221.00
337_S367_G2.1141.00
175_D179_A2.0821.00
475_Q506_E2.0821.00
392_A404_L2.0711.00
323_T326_E2.0651.00
302_H352_T2.0411.00
282_L295_A2.0401.00
476_V505_I2.0391.00
88_Q420_K2.0281.00
169_S173_T2.0251.00
361_A373_I2.0231.00
296_L387_I2.0201.00
297_L349_I2.0041.00
530_H546_Y2.0011.00
284_K293_Q1.9971.00
66_A131_N1.9931.00
260_A266_L1.9891.00
491_E495_K1.9831.00
26_M31_M1.9661.00
516_P520_F1.9601.00
26_M149_V1.9451.00
6_Y474_F1.9451.00
53_V452_V1.9441.00
548_Y551_N1.9021.00
69_V117_L1.8850.99
295_A343_M1.8780.99
478_I509_L1.8740.99
488_R540_D1.8710.99
165_T429_V1.8560.99
169_S172_E1.8420.99
334_G366_D1.8360.99
172_E176_A1.8270.99
160_A177_M1.8110.99
492_L539_L1.8080.99
478_I496_L1.8060.99
48_R506_E1.8010.99
272_L360_A1.7930.99
278_V359_F1.7800.99
122_L130_L1.7770.99
370_Y373_I1.7560.99
494_E498_S1.7370.99
348_V385_A1.7310.99
427_A439_L1.7270.99
320_T326_E1.7060.99
538_N556_L1.6900.99
64_A180_A1.6890.99
358_D374_N1.6870.99
353_V356_M1.6750.99
543_D558_K1.6720.99
348_V387_I1.6700.99
131_N160_A1.6630.99
296_L309_A1.6600.99
86_W105_V1.6560.99
227_S398_D1.6440.99
469_D475_Q1.6340.99
428_S436_N1.6320.98
92_E95_R1.6310.98
285_A319_L1.6290.98
365_I368_K1.6240.98
170_L416_Q1.6180.98
497_Y501_R1.6160.98
222_V403_L1.6130.98
107_G110_H1.6080.98
178_Y208_H1.5980.98
304_L309_A1.5950.98
284_K326_E1.5930.98
270_F371_F1.5860.98
64_A131_N1.5850.98
558_K561_D1.5780.98
492_L495_K1.5780.98
419_T440_T1.5770.98
333_A338_L1.5760.98
225_D404_L1.5740.98
561_D564_E1.5620.98
254_L370_Y1.5600.98
260_A269_Q1.5590.98
283_V304_L1.5550.98
337_S366_D1.5550.98
167_Q440_T1.5470.98
166_S169_S1.5460.98
270_F360_A1.5400.98
480_P509_L1.5360.98
327_I335_P1.5350.98
396_S400_Q1.5230.98
293_Q330_V1.5180.98
250_Q253_T1.5160.98
356_M359_F1.5090.97
483_M494_E1.5070.97
174_Y208_H1.4950.97
50_L449_T1.4940.97
49_V452_V1.4930.97
477_A523_M1.4880.97
565_Y568_K1.4800.97
19_E23_H1.4730.97
152_S449_T1.4550.97
182_S192_F1.4520.97
508_L528_I1.4520.97
220_D405_I1.4490.97
173_T176_A1.4420.97
252_M370_Y1.4210.96
429_V437_Q1.4100.96
55_N59_E1.4030.96
431_G437_Q1.4020.96
97_V101_E1.4000.96
73_V106_L1.4000.96
284_K320_T1.3780.96
12_K518_V1.3770.96
114_I132_F1.3760.96
74_V96_F1.3750.96
253_T372_G1.3680.95
247_A276_K1.3670.95
71_M114_I1.3650.95
561_D565_Y1.3530.95
64_A177_M1.3520.95
238_A390_V1.3490.95
263_I274_I1.3480.95
429_V439_L1.3460.95
259_N367_G1.3420.95
257_T369_H1.3410.95
64_A176_A1.3400.95
267_V274_I1.3390.95
263_I277_T1.3390.95
226_T400_Q1.3350.95
178_Y414_I1.3340.95
74_V94_L1.3340.95
282_L338_L1.3290.95
298_V304_L1.3250.95
60_E187_R1.3180.94
250_Q372_G1.3140.94
505_I567_V1.3060.94
308_K386_D1.3020.94
265_E268_E1.3010.94
469_D530_H1.3000.94
281_L304_L1.2900.94
207_S413_H1.2780.93
283_V306_E1.2730.93
546_Y565_Y1.2660.93
428_S438_I1.2610.93
359_F375_W1.2580.93
227_S400_Q1.2560.93
514_E518_V1.2540.93
531_T554_K1.2510.93
176_A180_A1.2510.93
503_Q567_V1.2420.92
42_W46_G1.2410.92
349_I381_T1.2360.92
297_L353_V1.2330.92
433_D437_Q1.2290.92
524_E547_K1.2230.92
354_A384_V1.2210.92
278_V297_L1.2190.92
26_M456_I1.2180.92
219_D232_N1.2160.92
349_I384_V1.2160.92
422_S427_A1.2140.92
55_N62_N1.2130.92
185_F446_I1.2130.92
235_L311_K1.2000.91
255_V270_F1.1980.91
81_Q103_P1.1950.91
118_I132_F1.1950.91
21_I460_Y1.1930.91
17_D27_L1.1930.91
476_V500_L1.1930.91
229_Y403_L1.1920.91
57_V449_T1.1890.91
33_R121_E1.1790.90
297_L347_V1.1780.90
223_F406_K1.1690.90
223_F404_L1.1660.90
280_T297_L1.1620.90
267_V277_T1.1620.90
530_H548_Y1.1620.90
165_T432_E1.1620.90
459_N550_R1.1590.90
255_V266_L1.1570.90
497_Y509_L1.1550.89
58_R68_E1.1550.89
63_N501_R1.1540.89
82_E425_L1.1460.89
336_G369_H1.1460.89
81_Q87_E1.1400.89
50_L156_L1.1370.89
118_I122_L1.1320.88
312_L387_I1.1310.88
202_I443_C1.1310.88
328_R334_G1.1290.88
51_K62_N1.1290.88
261_K265_E1.1280.88
420_K424_A1.1270.88
115_T427_A1.1260.88
479_L533_V1.1220.88
475_Q505_I1.1190.88
224_S400_Q1.1180.88
376_D380_A1.1160.88
489_V539_L1.1100.87
116_D119_R1.1090.87
156_L449_T1.1050.87
260_A337_S1.1010.87
492_L559_T1.0980.87
309_A387_I1.0910.87
83_S89_Y1.0900.87
324_E328_R1.0890.86
564_E568_K1.0860.86
52_K55_N1.0850.86
285_A313_P1.0840.86
333_A366_D1.0800.86
256_D365_I1.0800.86
480_P490_Q1.0760.86
36_A104_F1.0730.86
14_T27_L1.0710.86
419_T438_I1.0680.85
77_A103_P1.0670.85
263_I267_V1.0660.85
237_E351_R1.0660.85
562_I566_L1.0630.85
199_T207_S1.0630.85
228_D402_R1.0610.85
49_V467_W1.0570.85
47_V51_K1.0520.84
546_Y562_I1.0510.84
59_E63_N1.0480.84
430_Q435_R1.0470.84
197_A413_H1.0400.84
480_P493_A1.0370.84
266_L270_F1.0350.84
36_A39_L1.0340.83
70_S73_V1.0300.83
499_E502_A1.0290.83
56_I188_M1.0280.83
224_S398_D1.0270.83
263_I266_L1.0260.83
538_N543_D1.0250.83
21_I24_Q1.0240.83
164_H170_L1.0220.83
182_S186_S1.0210.83
538_N541_N1.0200.83
483_M490_Q1.0200.83
168_E171_Q1.0200.83
42_W50_L1.0140.82
31_M149_V1.0100.82
78_D81_Q1.0080.82
459_N466_V1.0070.82
116_D120_N1.0060.82
488_R492_L1.0020.81
252_M373_I1.0010.81
392_A405_I0.9990.81
43_L117_L0.9970.81
498_S502_A0.9950.81
532_I546_Y0.9900.81
537_R540_D0.9880.81
222_V405_I0.9870.80
199_T208_H0.9870.80
363_A368_K0.9840.80
74_V106_L0.9830.80
341_V370_Y0.9790.80
285_A316_A0.9790.80
546_Y557_I0.9790.80
225_D402_R0.9760.80
178_Y194_A0.9700.79
196_Q235_L0.9700.79
178_Y182_S0.9680.79
422_S438_I0.9670.79
246_A357_S0.9660.79
247_A358_D0.9620.79
530_H566_L0.9620.79
478_I493_A0.9580.78
79_L116_D0.9570.78
9_S43_L0.9560.78
212_V413_H0.9550.78
149_V152_S0.9550.78
299_R302_H0.9540.78
495_K559_T0.9530.78
280_T338_L0.9500.78
199_T235_L0.9460.78
532_I562_I0.9460.78
257_T336_G0.9450.78
423_E438_I0.9410.77
461_D549_R0.9390.77
476_V532_I0.9380.77
489_V492_L0.9380.77
346_P383_E0.9360.77
3_T477_A0.9340.77
480_P483_M0.9330.77
222_V390_V0.9330.77
461_D464_G0.9320.77
327_I333_A0.9310.76
479_L531_T0.9310.76
170_L206_A0.9290.76
279_K336_G0.9280.76
89_Y93_L0.9260.76
89_Y201_S0.9250.76
249_T357_S0.9230.76
501_R506_E0.9210.76
373_I379_V0.9190.76
3_T508_L0.9180.75
563_V567_V0.9160.75
296_L348_V0.9150.75
255_V269_Q0.9140.75
175_D178_Y0.9090.75
35_L41_T0.9070.75
312_L385_A0.9070.75
264_A274_I0.9060.74
488_R491_E0.9040.74
312_L348_V0.8990.74
110_H136_Q0.8920.73
353_V384_V0.8910.73
70_S136_Q0.8900.73
279_K369_H0.8870.73
179_A182_S0.8870.73
494_E509_L0.8860.73
170_L440_T0.8860.73
376_D379_V0.8840.73
300_G369_H0.8830.73
304_L387_I0.8820.72
250_Q371_F0.8790.72
293_Q322_A0.8780.72
558_K562_I0.8770.72
547_K554_K0.8720.72
422_S439_L0.8720.72
266_L269_Q0.8720.72
52_K475_Q0.8690.71
3_T8_L0.8680.71
478_I507_V0.8670.71
212_V411_V0.8670.71
409_I454_A0.8660.71
375_W384_V0.8650.71
20_V216_S0.8640.71
1_M497_Y0.8630.71
266_L360_A0.8620.71
353_V359_F0.8600.71
252_M377_R0.8590.70
302_H388_R0.8590.70
183_K186_S0.8590.70
423_E428_S0.8560.70
498_S501_R0.8550.70
479_L519_M0.8540.70
283_V321_F0.8530.70
53_V451_V0.8500.70
252_M341_V0.8500.70
287_E292_P0.8490.70
131_N177_M0.8450.69
379_V382_P0.8440.69
487_F490_Q0.8440.69
249_T358_D0.8430.69
478_I534_L0.8420.69
77_A86_W0.8410.69
349_I353_V0.8390.69
110_H134_Q0.8390.69
250_Q374_N0.8380.69
312_L383_E0.8350.68
283_V296_L0.8350.68
466_V550_R0.8350.68
179_A414_I0.8330.68
481_M535_G0.8320.68
158_K181_Y0.8270.68
334_G337_S0.8250.67
150_M216_S0.8240.67
258_P336_G0.8230.67
48_R52_K0.8220.67
456_I459_N0.8210.67
73_V136_Q0.8200.67
225_D228_D0.8190.67
31_M465_I0.8180.67
225_D401_G0.8170.67
206_A416_Q0.8140.66
196_Q208_H0.8120.66
261_K280_T0.8120.66
32_I149_V0.8120.66
46_G53_V0.8110.66
3_T523_M0.8090.66
431_G436_N0.8080.66
524_E531_T0.8070.66
6_Y45_T0.8050.65
331_V338_L0.8040.65
220_D407_R0.8030.65
182_S194_A0.8020.65
477_A528_I0.8010.65
496_L562_I0.8010.65
166_S432_E0.8000.65
177_M202_I0.7990.65
250_Q358_D0.7980.65
539_L559_T0.7940.64
258_P369_H0.7930.64
476_V562_I0.7920.64
260_A265_E0.7910.64
285_A292_P0.7900.64
284_K287_E0.7900.64
277_T338_L0.7890.64
215_Q406_K0.7890.64
214_A409_I0.7870.64
114_I443_C0.7850.63
307_V311_K0.7830.63
61_M158_K0.7820.63
269_Q371_F0.7820.63
258_P337_S0.7820.63
238_A394_D0.7820.63
299_R352_T0.7790.63
490_Q494_E0.7790.63
194_A413_H0.7790.63
64_A179_A0.7790.63
91_P143_V0.7770.63
501_R507_V0.7770.63
398_D401_G0.7770.63
89_Y202_I0.7750.62
423_E426_K0.7750.62
273_P276_K0.7750.62
237_E397_P0.7740.62
564_E567_V0.7730.62
331_V343_M0.7730.62
63_N179_A0.7720.62
196_Q398_D0.7710.62
483_M509_L0.7700.62
212_V458_Q0.7670.62
49_V528_I0.7670.62
56_I470_A0.7650.61
167_Q419_T0.7620.61
254_L363_A0.7610.61
212_V455_A0.7600.61
114_I208_H0.7590.61
272_L277_T0.7590.61
283_V309_A0.7590.61
188_M471_I0.7590.61
33_R43_L0.7580.61
233_I405_I0.7520.60
197_A207_S0.7520.60
164_H172_E0.7520.60
219_D413_H0.7510.60
460_Y466_V0.7490.60
320_T323_T0.7490.60
257_T279_K0.7480.60
21_I216_S0.7480.60
5_Q176_A0.7450.59
79_L93_L0.7430.59
128_L429_V0.7400.59
267_V270_F0.7400.59
286_V316_A0.7400.59
33_R117_L0.7390.59
341_V373_I0.7390.59
9_S33_R0.7390.59
35_L76_P0.7390.59
557_I565_Y0.7370.59
261_K337_S0.7360.58
42_W452_V0.7350.58
8_L526_I0.7330.58
128_L439_L0.7330.58
282_L322_A0.7320.58
478_I497_Y0.7310.58
300_G336_G0.7310.58
503_Q563_V0.7290.58
31_M456_I0.7280.58
302_H391_V0.7260.57
189_G459_N0.7250.57
35_L113_V0.7210.57
243_E355_A0.7200.57
39_L152_S0.7200.57
354_A375_W0.7150.56
257_T300_G0.7140.56
551_N555_Q0.7130.56
349_I354_A0.7120.56
57_V446_I0.7110.56
96_F106_L0.7100.56
56_I471_I0.7100.56
381_T384_V0.7100.56
303_E391_V0.7090.56
74_V105_V0.7070.55
328_R333_A0.7060.55
5_Q65_G0.7060.55
82_E116_D0.7050.55
324_E335_P0.7050.55
114_I202_I0.7040.55
279_K300_G0.7030.55
51_K55_N0.7010.55
396_S401_G0.7010.55
474_F506_E0.7000.55
41_T71_M0.7000.55
126_K435_R0.6990.55
326_E329_A0.6990.55
188_M451_V0.6960.54
47_V54_E0.6960.54
376_D381_T0.6950.54
395_P402_R0.6940.54
191_D458_Q0.6930.54
86_W103_P0.6920.54
533_V554_K0.6900.54
108_P207_S0.6890.54
259_N337_S0.6890.54
480_P489_V0.6870.53
165_T169_S0.6870.53
459_N465_I0.6860.53
375_W379_V0.6860.53
231_A236_A0.6850.53
256_D259_N0.6840.53
293_Q326_E0.6840.53
216_S220_D0.6830.53
281_L335_P0.6820.53
469_D546_Y0.6800.53
171_Q206_A0.6800.53
482_N516_P0.6790.52
535_G541_N0.6780.52
98_D102_R0.6780.52
278_V361_A0.6770.52
118_I130_L0.6770.52
118_I513_K0.6760.52
477_A508_L0.6760.52
351_R354_A0.6740.52
360_A371_F0.6730.52
83_S191_D0.6730.52
12_K521_A0.6720.52
341_V379_V0.6680.51
255_V371_F0.6670.51
59_E183_K0.6670.51
481_M516_P0.6660.51
81_Q86_W0.6660.51
328_R366_D0.6650.51
53_V471_I0.6630.51
94_L106_L0.6630.51
164_H443_C0.6620.51
460_Y465_I0.6610.51
93_L202_I0.6600.50
256_D337_S0.6600.50
316_A319_L0.6590.50
20_V34_K0.6550.50
299_R388_R0.6540.50
351_R384_V0.6540.50
75_Q113_V0.6530.50
71_M113_V0.6520.50
149_V449_T0.6520.50
64_A173_T0.6510.49
415_F445_G0.6510.49
495_K502_A0.6490.49
413_H451_V0.6480.49
94_L105_V0.6480.49
99_R141_D0.6460.49
67_I130_L0.6460.49
493_A509_L0.6450.49
263_I279_K0.6450.49
15_P23_H0.6450.49
532_I566_L0.6450.49
262_T265_E0.6430.49
262_T300_G0.6430.49
463_R552_G0.6410.48
455_A459_N0.6400.48
548_Y555_Q0.6400.48
557_I562_I0.6390.48
531_T551_N0.6380.48
62_N65_G0.6360.48
551_N554_K0.6360.48
410_E415_F0.6360.48
75_Q114_I0.6350.48
216_S455_A0.6340.48
353_V375_W0.6330.48
211_Q233_I0.6330.48
74_V139_F0.6330.48
73_V137_T0.6330.48
541_N556_L0.6320.47
540_D543_D0.6320.47
430_Q436_N0.6310.47
222_V233_I0.6310.47
45_T526_I0.6310.47
333_A337_S0.6280.47
37_S147_F0.6270.47
426_K438_I0.6260.47
278_V356_M0.6260.47
143_V150_M0.6250.47
149_V453_A0.6240.47
19_E34_K0.6220.46
237_E398_D0.6220.46
256_D260_A0.6210.46
309_A385_A0.6210.46
353_V379_V0.6200.46
286_V314_Q0.6200.46
88_Q201_S0.6190.46
89_Y95_R0.6180.46
64_A160_A0.6180.46
281_L295_A0.6170.46
89_Y152_S0.6160.46
119_R425_L0.6150.46
264_A303_E0.6140.46
23_H34_K0.6140.46
238_A386_D0.6130.45
259_N542_D0.6120.45
199_T206_A0.6120.45
179_A186_S0.6110.45
448_V485_K0.6110.45
7_L67_I0.6100.45
126_K513_K0.6100.45
280_T327_I0.6090.45
184_I446_I0.6080.45
534_L539_L0.6070.45
240_A351_R0.6070.45
298_V352_T0.6060.45
54_E58_R0.6060.45
79_L113_V0.6050.45
152_S156_L0.6040.44
325_E328_R0.6020.44
277_T327_I0.6010.44
279_K362_G0.6010.44
482_N485_K0.6010.44
482_N486_S0.6010.44
233_I389_N0.6000.44
426_K436_N0.6000.44
47_V489_V0.6000.44
313_P346_P0.5990.44
164_H176_A0.5990.44
336_G339_G0.5980.44
322_A327_I0.5980.44
544_I559_T0.5970.44
73_V105_V0.5970.44
150_M214_A0.5970.44
58_R62_N0.5960.44
427_A438_I0.5960.44
151_R415_F0.5960.44
193_R213_L0.5930.43
52_K56_I0.5920.43
278_V375_W0.5910.43
295_A331_V0.5910.43
475_Q528_I0.5900.43
282_L331_V0.5890.43
258_P300_G0.5860.43
7_L152_S0.5850.42
241_P355_A0.5850.42
436_N524_E0.5850.42
160_A443_C0.5840.42
53_V57_V0.5830.42
245_R357_S0.5820.42
82_E426_K0.5820.42
35_L137_T0.5820.42
49_V456_I0.5820.42
7_L132_F0.5810.42
295_A345_I0.5810.42
166_S440_T0.5800.42
46_G452_V0.5800.42
331_V334_G0.5790.42
83_S95_R0.5790.42
168_E172_E0.5780.42
390_V393_G0.5770.42
246_A276_K0.5770.42
499_E503_Q0.5770.42
274_I277_T0.5770.42
548_Y552_G0.5760.42
499_E563_V0.5760.42
280_T346_P0.5760.42
292_P344_P0.5720.41
262_T266_L0.5720.41
63_N180_A0.5720.41
296_L304_L0.5720.41
496_L534_L0.5720.41
333_A361_A0.5710.41
89_Y108_P0.5710.41
199_T211_Q0.5700.41
456_I460_Y0.5700.41
327_I338_L0.5690.41
157_M415_F0.5690.41
294_V319_L0.5690.41
171_Q440_T0.5670.41
108_P197_A0.5660.40
346_P382_P0.5650.40
547_K552_G0.5640.40
499_E564_E0.5620.40
261_K338_L0.5620.40
151_R410_E0.5620.40
303_E389_N0.5610.40
199_T311_K0.5610.40
483_M486_S0.5610.40
228_D401_G0.5610.40
157_M445_G0.5600.40
7_L282_L0.5590.40
71_M75_Q0.5590.40
375_W382_P0.5590.40
335_P338_L0.5580.40
325_E329_A0.5580.40
42_W152_S0.5570.40
18_A23_H0.5570.40
40_Y409_I0.5560.39
419_T422_S0.5560.39
257_T263_I0.5560.39
474_F508_L0.5550.39
201_S307_V0.5550.39
326_E330_V0.5550.39
354_A381_T0.5540.39
416_Q440_T0.5530.39
324_E334_G0.5530.39
199_T205_S0.5520.39
263_I369_H0.5520.39
280_T345_I0.5510.39
280_T335_P0.5510.39
348_V383_E0.5500.39
34_K143_V0.5500.39
276_K358_D0.5480.39
232_N413_H0.5480.39
59_E81_Q0.5470.39
200_G415_F0.5470.39
62_N66_A0.5470.39
55_N63_N0.5460.38
535_G543_D0.5460.38
229_Y236_A0.5450.38
107_G212_V0.5450.38
20_V453_A0.5420.38
435_R513_K0.5420.38
41_T72_P0.5410.38
63_N502_A0.5410.38
106_L152_S0.5400.38
532_I544_I0.5400.38
260_A361_A0.5400.38
89_Y449_T0.5400.38
127_Q477_A0.5390.38
277_T360_A0.5390.38
501_R505_I0.5380.38
151_R200_G0.5380.38
107_G134_Q0.5380.38
431_G435_R0.5370.38
188_M211_Q0.5370.38
435_R524_E0.5360.37
19_E102_R0.5360.37
202_I422_S0.5360.37
263_I336_G0.5360.37
310_E318_P0.5360.37
198_D311_K0.5350.37
180_A184_I0.5340.37
75_Q202_I0.5340.37
143_V214_A0.5340.37
126_K429_V0.5330.37
239_I400_Q0.5330.37
313_P348_V0.5320.37
67_I519_M0.5320.37
46_G156_L0.5320.37
339_G364_N0.5310.37
362_G369_H0.5310.37
11_L514_E0.5310.37
137_T219_D0.5300.37
192_F411_V0.5290.37
250_Q276_K0.5280.37
122_L128_L0.5280.37
89_Y143_V0.5280.37
238_A351_R0.5280.37
285_A294_V0.5270.37
149_V456_I0.5270.37
463_R524_E0.5270.37
306_E403_L0.5270.37
21_I459_N0.5260.36
280_T333_A0.5260.36
211_Q440_T0.5260.36
48_R62_N0.5250.36
35_L116_D0.5230.36
475_Q501_R0.5230.36
562_I567_V0.5220.36
336_G340_P0.5220.36
185_F534_L0.5220.36
107_G136_Q0.5220.36
80_W84_G0.5210.36
202_I439_L0.5210.36
9_S45_T0.5200.36
126_K433_D0.5200.36
269_Q360_A0.5200.36
190_L454_A0.5190.36
375_W381_T0.5190.36
27_L221_V0.5180.36
20_V212_V0.5180.36
421_Y445_G0.5170.36
222_V235_L0.5170.36
246_A249_T0.5170.36
50_L70_S0.5160.35
364_N369_H0.5160.35
92_E100_G0.5160.35
266_L369_H0.5150.35
89_Y92_E0.5140.35
15_P18_A0.5140.35
31_M303_E0.5130.35
248_A372_G0.5130.35
383_E387_I0.5130.35
147_F408_G0.5120.35
339_G362_G0.5120.35
469_D550_R0.5110.35
176_A179_A0.5110.35
73_V219_D0.5100.35
115_T443_C0.5090.35
464_G549_R0.5090.35
425_L439_L0.5080.35
6_Y31_M0.5070.35
267_V272_L0.5070.35
282_L333_A0.5070.35
532_I557_I0.5070.35
510_D519_M0.5060.34
182_S414_I0.5050.34
293_Q524_E0.5050.34
84_G180_A0.5040.34
228_D400_Q0.5040.34
13_E459_N0.5040.34
147_F214_A0.5030.34
92_E104_F0.5020.34
66_A133_Y0.5020.34
167_Q171_Q0.5020.34
397_P400_Q0.5010.34
26_M51_K0.5000.34
93_L443_C0.5000.34
41_T449_T0.5000.34
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2j3lA 2 0.9878 100 0.45 Contact Map
2i4lA 2 0.7657 100 0.537 Contact Map
4phcA 2 0.7762 100 0.65 Contact Map
4hvcA 2 0.6573 100 0.674 Contact Map
2zt5A 2 0.7238 100 0.677 Contact Map
1qf6A 1 0.7028 100 0.685 Contact Map
1nj8A 2 0.6434 100 0.691 Contact Map
3ialA 2 0.6538 100 0.692 Contact Map
1nj1A 2 0.6399 100 0.699 Contact Map
4ncxA 2 0.6084 100 0.702 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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