AROP - ECOLI - GREMLIN Contacts

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AROP - Aromatic amino acid transport protein AroP

UniProt:	P15993	Sequences: MMEGQQHGEQLKRGLKNRHIQLIALGGAIGTGLFLGSASVIQSAGPGIILGYAIAGFIAFLIMRQLGEMVVEEPVAGSFSHFAYKYWGSFAGFASGWNYWVLYVLVAMAELTAVGKYIQFWYPEIPTWVSAAVFFVVINAINLTNVKVFGEMEFWFAIIKVIAVVAMIIFGGWLLFSGNGGPQATVSNLWDQGGFLPHGFTGLVMMMAIIMFSFGGLELVGITAAEADNPEQSIPKATNQVIYRILIFYIGSLAVLLSLMPWTRVTADTSPFVLIFHELGDTFVANALNIVVLTAALSVYNSCVYCNSRMLFGLAQQGNAPKALASVDKRGVPVNTILVSALVTALCVLINYLAPESAFGLLMALVVSALVINWAMISLAHMKFRRAKQEQGVVTRFPALLYPLGNWICLLFMAAVLVIMLMTPGMAISVYLIPVWLIVLGIGYLFKEKTAKAVKAH	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10084
Length:	457 (423)
Sequences:	24764 (15871)
Seq/√Len:	771.7

ECOLI - AROP MMUP YIFK PROY PHEP GABP ANSP CYCA FRLA LYSP POTE PUUP PLAP YCAM GADC ADIC YGJI YJEM YBAT CADB ARCD YJEH TNAB
BACSU - ROCC HUTM AAPA YTNA YBXG YDGF YBGF GABP ROCE YVBW ASPP YBEC YHDG STET YFNA YCGH ARCD YECA YDAO GERBB GERAB YNDE GERKB YFKT
HALSA - Q9HHU7 Q9HQB3 Q9HSL5
SULSO - Q97X49 Q97WS3 Q97U05 Q97XM0 Q97ZB5 Q7LXI7 Q97Z63 Q97U33 Q97VA6 Q97WD4 Q97VA8 Q97VR4 Q97Y76 Q97YX9 Q97YN3 Q97U39

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
139_N	341_A	4.420	1.00
323_A	335_N	4.374	1.00
383_K	387_A	3.542	1.00
375_A	410_L	3.270	1.00
56_G	246_L	3.225	1.00
326_S	335_N	3.114	1.00
232_Q	236_K	2.944	1.00
16_K	228_D	2.878	1.00
227_A	233_S	2.695	1.00
96_G	314_L	2.654	1.00
80_S	317_Q	2.625	1.00
229_N	232_Q	2.593	1.00
21_Q	240_Q	2.579	1.00
315_A	325_A	2.574	1.00
171_G	255_V	2.573	1.00
328_D	334_V	2.526	1.00
323_A	326_S	2.472	1.00
132_A	345_A	2.471	1.00
283_F	287_A	2.401	1.00
17_N	240_Q	2.400	1.00
225_A	316_Q	2.345	1.00
169_I	173_W	2.302	1.00
378_S	409_C	2.261	1.00
431_Y	435_V	2.255	1.00
84_Y	92_G	2.253	1.00
68_E	385_R	2.187	1.00
226_E	309_R	2.164	1.00
140_A	144_T	2.140	1.00
274_L	277_H	2.126	1.00
338_L	342_L	2.121	1.00
312_F	316_Q	2.109	1.00
17_N	233_S	2.086	1.00
147_K	151_E	2.086	1.00
87_W	383_K	2.083	1.00
407_W	411_L	2.074	1.00
136_V	345_A	2.065	1.00
435_V	438_I	2.057	1.00
20_I	227_A	2.056	1.00
139_N	337_I	2.038	1.00
17_N	21_Q	2.013	1.00
143_L	334_V	1.997	1.00
441_G	445_L	1.984	1.00
158_I	162_I	1.982	1.00
236_K	240_Q	1.959	1.00
132_A	348_V	1.953	1.00
21_Q	244_R	1.922	1.00
65_Q	378_S	1.911	1.00
438_I	442_I	1.911	1.00
131_A	348_V	1.899	1.00
84_Y	89_S	1.899	1.00
16_K	19_H	1.898	1.00
87_W	379_L	1.882	1.00
261_P	264_R	1.882	1.00
324_L	339_V	1.877	1.00
379_L	410_L	1.867	1.00
57_F	61_L	1.839	1.00
100_W	340_S	1.838	1.00
40_V	48_I	1.833	1.00
318_G	322_K	1.823	1.00
11_L	327_V	1.809	1.00
264_R	278_E	1.807	1.00
239_N	243_Y	1.805	1.00
274_L	278_E	1.765	1.00
404_L	408_I	1.757	1.00
83_A	95_S	1.709	1.00
136_V	341_A	1.709	1.00
47_G	203_L	1.707	1.00
186_V	189_L	1.698	1.00
328_D	332_V	1.697	1.00
229_N	233_S	1.695	1.00
411_L	415_A	1.694	1.00
95_S	376_M	1.683	1.00
19_H	154_F	1.677	1.00
24_A	241_V	1.657	1.00
330_R	334_V	1.650	1.00
135_F	344_T	1.641	1.00
58_I	412_F	1.636	1.00
107_A	344_T	1.632	1.00
143_L	338_L	1.631	1.00
142_N	301_N	1.624	1.00
51_G	206_M	1.609	1.00
436_W	440_L	1.608	1.00
126_P	129_V	1.606	1.00
383_K	386_R	1.601	1.00
111_L	300_Y	1.597	1.00
15_L	19_H	1.594	1.00
88_G	91_A	1.590	1.00
162_I	166_A	1.574	1.00
439_V	443_G	1.555	1.00
243_Y	247_I	1.555	1.00
435_V	439_V	1.514	1.00
437_L	441_G	1.501	1.00
335_N	339_V	1.500	1.00
118_I	130_S	1.500	1.00
277_H	285_A	1.493	1.00
440_L	443_G	1.485	1.00
163_A	291_V	1.478	1.00
311_L	336_T	1.461	1.00
55_A	210_I	1.458	1.00
312_F	327_V	1.452	1.00
307_N	340_S	1.452	1.00
223_T	305_Y	1.435	1.00
61_L	408_I	1.429	1.00
135_F	341_A	1.424	1.00
229_N	236_K	1.422	1.00
144_T	330_R	1.420	1.00
12_K	331_G	1.416	1.00
83_A	376_M	1.411	1.00
428_I	431_Y	1.404	1.00
76_A	225_A	1.402	1.00
63_M	242_I	1.396	1.00
57_F	408_I	1.394	1.00
111_L	135_F	1.390	1.00
427_A	430_V	1.384	1.00
379_L	383_K	1.382	1.00
426_M	429_S	1.381	1.00
11_L	312_F	1.381	1.00
139_N	338_L	1.378	1.00
114_V	293_L	1.377	1.00
132_A	136_V	1.365	1.00
322_K	325_A	1.364	1.00
172_G	255_V	1.359	1.00
326_S	334_V	1.348	1.00
434_P	438_I	1.340	1.00
161_V	165_V	1.336	1.00
308_S	337_I	1.336	1.00
247_I	251_G	1.335	1.00
322_K	326_S	1.334	1.00
114_V	134_F	1.327	1.00
268_D	274_L	1.307	1.00
175_L	258_S	1.306	1.00
286_N	290_I	1.301	1.00
87_W	91_A	1.300	1.00
389_Q	395_T	1.299	1.00
425_G	428_I	1.297	1.00
19_H	150_G	1.294	1.00
233_S	236_K	1.293	1.00
168_I	251_G	1.289	1.00
428_I	435_V	1.285	1.00
425_G	439_V	1.284	1.00
125_I	129_V	1.278	1.00
270_S	274_L	1.269	1.00
75_V	81_H	1.269	1.00
63_M	238_T	1.266	1.00
73_E	85_K	1.266	1.00
433_I	437_L	1.265	1.00
382_M	407_W	1.255	1.00
62_I	378_S	1.250	1.00
49_I	254_A	1.250	1.00
17_N	236_K	1.237	1.00
81_H	85_K	1.234	1.00
15_L	20_I	1.233	1.00
401_L	405_G	1.232	1.00
18_R	22_L	1.231	1.00
230_P	235_P	1.230	1.00
90_F	444_Y	1.226	1.00
429_S	433_I	1.226	1.00
277_H	282_T	1.225	1.00
415_A	419_I	1.224	1.00
65_Q	406_N	1.223	1.00
392_G	395_T	1.217	1.00
35_L	113_A	1.212	1.00
64_R	239_N	1.210	1.00
193_G	197_P	1.204	1.00
28_A	245_I	1.201	1.00
86_Y	380_A	1.196	1.00
110_E	299_V	1.195	1.00
173_W	178_G	1.195	1.00
75_V	85_K	1.190	1.00
186_V	190_W	1.183	1.00
138_I	300_Y	1.183	1.00
47_G	196_L	1.177	1.00
187_S	190_W	1.173	1.00
141_I	152_M	1.169	1.00
426_M	430_V	1.168	1.00
15_L	150_G	1.163	1.00
375_A	414_A	1.158	1.00
176_F	179_N	1.158	1.00
262_W	265_V	1.157	1.00
20_I	237_A	1.151	1.00
171_G	259_L	1.149	1.00
311_L	320_A	1.138	1.00
404_L	407_W	1.136	1.00
172_G	176_F	1.133	1.00
167_M	171_G	1.130	1.00
83_A	91_A	1.127	1.00
128_W	132_A	1.125	1.00
100_W	311_L	1.124	1.00
401_L	404_L	1.115	1.00
24_A	220_V	1.110	1.00
386_R	389_Q	1.106	1.00
66_L	79_F	1.103	1.00
335_N	338_L	1.099	1.00
439_V	445_L	1.093	1.00
23_I	223_T	1.080	1.00
424_P	427_A	1.079	1.00
152_M	156_F	1.078	1.00
228_D	233_S	1.077	1.00
425_G	431_Y	1.077	1.00
41_I	48_I	1.075	1.00
431_Y	438_I	1.072	1.00
316_Q	325_A	1.072	1.00
14_G	228_D	1.068	1.00
85_K	388_K	1.068	1.00
133_V	137_V	1.065	1.00
70_V	82_F	1.063	1.00
386_R	403_P	1.062	1.00
93_F	97_W	1.053	1.00
166_A	170_F	1.046	1.00
25_L	244_R	1.045	1.00
403_P	407_W	1.043	1.00
327_V	331_G	1.041	1.00
72_E	395_T	1.040	1.00
414_A	418_V	1.039	1.00
440_L	444_Y	1.039	1.00
151_E	155_W	1.035	1.00
425_G	429_S	1.034	1.00
118_I	122_Y	1.031	1.00
389_Q	392_G	1.025	1.00
115_G	130_S	1.020	1.00
25_L	245_I	1.016	1.00
381_H	406_N	1.016	1.00
153_E	301_N	1.012	1.00
402_Y	406_N	1.011	1.00
424_P	428_I	1.005	1.00
80_S	313_G	1.005	1.00
385_R	389_Q	1.003	1.00
136_V	140_A	1.003	1.00
68_E	71_V	0.996	1.00
53_A	250_I	0.995	1.00
342_L	346_L	0.991	1.00
425_G	438_I	0.989	1.00
388_K	393_V	0.988	1.00
118_I	293_L	0.988	1.00
261_P	278_E	0.986	1.00
410_L	414_A	0.981	1.00
165_V	169_I	0.981	1.00
139_N	143_L	0.981	1.00
146_V	305_Y	0.979	1.00
143_L	332_V	0.976	1.00
129_V	133_V	0.973	1.00
204_V	415_A	0.973	1.00
156_F	298_S	0.968	1.00
224_A	234_I	0.963	1.00
393_V	396_R	0.950	1.00
215_G	370_L	0.948	1.00
435_V	440_L	0.944	1.00
418_V	422_M	0.943	1.00
378_S	410_L	0.938	1.00
168_I	255_V	0.932	1.00
22_L	154_F	0.924	1.00
196_L	203_L	0.924	1.00
427_A	431_Y	0.924	1.00
109_A	212_F	0.923	1.00
29_I	32_G	0.921	1.00
161_V	248_F	0.918	1.00
173_W	177_S	0.916	1.00
77_G	81_H	0.915	1.00
246_L	250_I	0.911	1.00
437_L	440_L	0.903	1.00
200_F	203_L	0.900	1.00
282_T	286_N	0.896	1.00
137_V	297_L	0.896	1.00
375_A	413_M	0.892	1.00
61_L	405_G	0.890	1.00
49_I	257_L	0.888	1.00
240_Q	244_R	0.886	1.00
143_L	328_D	0.885	1.00
432_L	435_V	0.884	1.00
280_G	284_V	0.878	1.00
218_E	222_I	0.878	1.00
130_S	133_V	0.877	1.00
175_L	178_G	0.875	1.00
191_D	194_G	0.875	1.00
62_I	413_M	0.874	1.00
429_S	435_V	0.874	1.00
160_K	295_A	0.874	1.00
254_A	258_S	0.869	1.00
138_I	301_N	0.863	1.00
431_Y	442_I	0.862	1.00
18_R	154_F	0.859	1.00
14_G	147_K	0.857	1.00
84_Y	317_Q	0.857	1.00
199_G	202_G	0.854	1.00
109_A	363_M	0.854	1.00
415_A	418_V	0.853	1.00
115_G	131_A	0.852	1.00
324_L	335_N	0.847	1.00
304_V	341_A	0.846	1.00
168_I	172_G	0.841	1.00
431_Y	434_P	0.841	1.00
334_V	338_L	0.840	1.00
72_E	393_V	0.838	1.00
119_Q	123_P	0.838	1.00
19_H	151_E	0.838	1.00
375_A	379_L	0.837	1.00
11_L	226_E	0.833	1.00
115_G	127_T	0.832	1.00
11_L	309_R	0.832	1.00
409_C	413_M	0.831	1.00
60_F	64_R	0.831	1.00
90_F	94_A	0.829	1.00
188_N	191_D	0.827	1.00
53_A	57_F	0.826	1.00
441_G	444_Y	0.823	1.00
114_V	297_L	0.821	1.00
50_L	203_L	0.820	1.00
382_M	406_N	0.820	1.00
328_D	331_G	0.819	1.00
56_G	214_F	0.818	1.00
196_L	199_G	0.818	1.00
388_K	392_G	0.816	1.00
112_T	362_L	0.811	1.00
426_M	439_V	0.810	1.00
97_W	320_A	0.810	1.00
91_A	376_M	0.810	1.00
114_V	296_A	0.810	1.00
320_A	324_L	0.807	1.00
259_L	275_I	0.807	1.00
205_M	209_I	0.805	1.00
438_I	441_G	0.802	1.00
128_W	348_V	0.801	1.00
425_G	442_I	0.799	1.00
151_E	154_F	0.799	1.00
428_I	438_I	0.798	1.00
219_L	306_C	0.793	1.00
341_A	345_A	0.793	1.00
77_G	80_S	0.787	1.00
413_M	416_V	0.786	1.00
430_V	434_P	0.786	1.00
442_I	445_L	0.785	1.00
60_F	239_N	0.782	1.00
175_L	179_N	0.782	1.00
140_A	143_L	0.780	1.00
173_W	176_F	0.777	1.00
382_M	386_R	0.770	1.00
172_G	251_G	0.770	1.00
436_W	439_V	0.766	1.00
194_G	197_P	0.766	1.00
69_M	381_H	0.765	1.00
17_N	237_A	0.764	1.00
429_S	434_P	0.763	1.00
83_A	380_A	0.759	1.00
439_V	444_Y	0.759	1.00
88_G	445_L	0.757	1.00
268_D	271_P	0.754	1.00
61_L	65_Q	0.753	1.00
281_D	284_V	0.753	1.00
135_F	348_V	0.752	1.00
189_L	193_G	0.751	1.00
365_L	369_A	0.751	1.00
431_Y	436_W	0.747	1.00
425_G	435_V	0.747	1.00
29_I	34_F	0.741	1.00
119_Q	127_T	0.741	1.00
14_G	146_V	0.741	1.00
193_G	196_L	0.740	1.00
215_G	374_W	0.738	1.00
329_K	334_V	0.738	1.00
429_S	438_I	0.734	1.00
417_L	420_M	0.733	1.00
342_L	345_A	0.733	1.00
270_S	273_V	0.733	1.00
69_M	82_F	0.728	1.00
167_M	276_F	0.726	1.00
426_M	433_I	0.726	1.00
394_V	398_P	0.725	1.00
168_I	252_S	0.723	1.00
104_V	343_V	0.720	1.00
402_Y	405_G	0.717	1.00
144_T	148_V	0.716	1.00
143_L	330_R	0.716	1.00
426_M	431_Y	0.715	1.00
29_I	160_K	0.714	1.00
433_I	436_W	0.713	1.00
18_R	151_E	0.713	1.00
99_Y	103_Y	0.713	1.00
200_F	204_V	0.712	1.00
324_L	336_T	0.710	1.00
176_F	180_G	0.710	1.00
276_F	279_L	0.709	1.00
235_P	238_T	0.708	1.00
138_I	304_V	0.708	1.00
50_L	54_I	0.706	1.00
195_F	198_H	0.704	1.00
30_G	34_F	0.702	1.00
368_S	417_L	0.699	1.00
59_A	217_L	0.697	1.00
87_W	380_A	0.696	1.00
323_A	339_V	0.696	1.00
124_E	127_T	0.693	1.00
28_A	241_V	0.693	1.00
50_L	53_A	0.691	1.00
14_G	18_R	0.691	1.00
428_I	439_V	0.690	1.00
406_N	410_L	0.688	1.00
431_Y	443_G	0.688	1.00
229_N	235_P	0.687	1.00
40_V	44_A	0.687	1.00
64_R	405_G	0.685	1.00
381_H	385_R	0.683	1.00
380_A	384_F	0.683	1.00
399_A	402_Y	0.681	1.00
432_L	436_W	0.680	1.00
397_F	400_L	0.678	1.00
142_N	337_I	0.676	1.00
382_M	403_P	0.676	1.00
429_S	440_L	0.675	1.00
108_M	362_L	0.671	1.00
49_I	53_A	0.668	1.00
33_L	252_S	0.667	1.00
333_P	336_T	0.666	1.00
438_I	445_L	0.664	1.00
106_V	366_V	0.664	1.00
308_S	336_T	0.663	1.00
240_Q	243_Y	0.660	1.00
311_L	339_V	0.658	1.00
425_G	440_L	0.658	1.00
244_R	248_F	0.658	1.00
428_I	441_G	0.657	1.00
66_L	377_I	0.657	1.00
148_V	151_E	0.657	1.00
271_P	276_F	0.657	1.00
142_N	305_Y	0.655	1.00
54_I	207_M	0.654	1.00
138_I	297_L	0.652	1.00
21_Q	237_A	0.652	1.00
115_G	118_I	0.651	1.00
105_L	365_L	0.650	1.00
427_A	441_G	0.650	1.00
80_S	84_Y	0.649	1.00
283_F	286_N	0.649	1.00
202_G	205_M	0.649	1.00
369_A	373_N	0.647	1.00
431_Y	440_L	0.646	1.00
48_I	253_L	0.645	1.00
304_V	308_S	0.643	1.00
37_S	253_L	0.642	1.00
309_R	312_F	0.641	1.00
128_W	131_A	0.640	1.00
430_V	433_I	0.640	1.00
132_A	349_L	0.636	1.00
244_R	247_I	0.636	1.00
65_Q	409_C	0.636	1.00
136_V	139_N	0.635	1.00
170_F	174_L	0.634	1.00
46_P	257_L	0.634	1.00
39_S	360_G	0.633	1.00
120_F	289_N	0.633	1.00
26_G	157_A	0.632	1.00
175_L	255_V	0.632	1.00
407_W	410_L	0.630	1.00
418_V	421_L	0.630	1.00
52_Y	213_S	0.629	1.00
221_G	238_T	0.627	1.00
315_A	324_L	0.626	1.00
86_Y	383_K	0.625	1.00
267_A	270_S	0.623	1.00
27_G	303_C	0.622	1.00
49_I	250_I	0.622	1.00
18_R	21_Q	0.621	1.00
416_V	420_M	0.621	1.00
29_I	248_F	0.619	1.00
399_A	405_G	0.618	1.00
400_L	404_L	0.617	1.00
411_L	414_A	0.615	1.00
150_G	154_F	0.615	1.00
435_V	442_I	0.615	1.00
63_M	217_L	0.614	1.00
434_P	437_L	0.614	1.00
177_S	180_G	0.614	1.00
295_A	298_S	0.613	1.00
433_I	438_I	0.611	1.00
79_F	218_E	0.611	1.00
27_G	302_S	0.610	1.00
36_G	363_M	0.608	1.00
121_W	290_I	0.608	1.00
395_T	398_P	0.607	1.00
76_A	312_F	0.607	1.00
21_Q	24_A	0.607	1.00
431_Y	437_L	0.606	1.00
439_V	442_I	0.605	1.00
80_S	96_G	0.604	1.00
215_G	218_E	0.601	1.00
252_S	256_L	0.601	1.00
425_G	430_V	0.601	1.00
98_N	373_N	0.598	1.00
86_Y	384_F	0.598	1.00
55_A	211_M	0.598	1.00
102_L	370_L	0.596	1.00
225_A	312_F	0.594	1.00
434_P	440_L	0.592	1.00
61_L	409_C	0.591	1.00
145_N	148_V	0.589	1.00
424_P	431_Y	0.588	1.00
430_V	440_L	0.588	1.00
307_N	311_L	0.587	1.00
170_F	281_D	0.586	1.00
191_D	195_F	0.586	1.00
69_M	86_Y	0.585	1.00
431_Y	441_G	0.585	1.00
159_I	291_V	0.584	1.00
234_I	238_T	0.582	1.00
113_A	117_Y	0.582	1.00
70_V	234_I	0.581	1.00
192_Q	195_F	0.581	1.00
70_V	221_G	0.580	1.00
72_E	389_Q	0.580	1.00
65_Q	399_A	0.578	1.00
67_G	71_V	0.578	1.00
436_W	444_Y	0.577	1.00
106_V	110_E	0.575	1.00
106_V	109_A	0.575	1.00
146_V	223_T	0.575	1.00
371_V	413_M	0.574	1.00
433_I	444_Y	0.573	1.00
134_F	300_Y	0.572	1.00
159_I	163_A	0.572	1.00
436_W	442_I	0.572	1.00
143_L	337_I	0.572	1.00
427_A	436_W	0.571	1.00
63_M	67_G	0.571	1.00
110_E	300_Y	0.569	1.00
139_N	304_V	0.569	1.00
98_N	372_I	0.569	1.00
403_P	406_N	0.567	1.00
118_I	134_F	0.567	1.00
227_A	234_I	0.566	1.00
222_I	306_C	0.565	1.00
135_F	345_A	0.565	1.00
187_S	191_D	0.564	1.00
108_M	347_C	0.564	1.00
231_E	394_V	0.564	1.00
117_Y	292_V	0.563	1.00
428_I	433_I	0.563	1.00
267_A	271_P	0.563	1.00
157_A	160_K	0.562	1.00
149_F	305_Y	0.562	1.00
251_G	255_V	0.560	1.00
427_A	438_I	0.559	1.00
148_V	152_M	0.559	1.00
427_A	445_L	0.559	1.00
272_F	276_F	0.559	1.00
425_G	436_W	0.558	1.00
83_A	92_G	0.558	1.00
78_S	221_G	0.557	1.00
426_M	436_W	0.557	1.00
162_I	165_V	0.557	1.00
428_I	437_L	0.556	1.00
55_A	214_F	0.555	1.00
24_A	28_A	0.554	1.00
103_Y	303_C	0.554	1.00
110_E	113_A	0.554	1.00
401_L	406_N	0.554	1.00
110_E	296_A	0.550	1.00
409_C	412_F	0.549	1.00
290_I	294_T	0.549	1.00
419_I	423_T	0.549	1.00
215_G	366_V	0.548	1.00
31_T	212_F	0.547	1.00
266_T	270_S	0.545	1.00
134_F	297_L	0.545	1.00
431_Y	439_V	0.544	1.00
384_F	388_K	0.544	1.00
163_A	287_A	0.542	1.00
255_V	258_S	0.542	1.00
430_V	435_V	0.542	1.00
111_L	115_G	0.542	1.00
27_G	219_L	0.542	1.00
385_R	402_Y	0.540	1.00
287_A	291_V	0.539	1.00
204_V	419_I	0.539	1.00
426_M	435_V	0.539	1.00
116_K	127_T	0.539	1.00
271_P	279_L	0.538	1.00
345_A	348_V	0.538	1.00
155_W	159_I	0.537	1.00
428_I	432_L	0.536	1.00
40_V	206_M	0.536	1.00
276_F	281_D	0.535	1.00
137_V	141_I	0.534	1.00
80_S	92_G	0.532	1.00
25_L	157_A	0.532	1.00
360_G	363_M	0.532	1.00
95_S	373_N	0.531	1.00
226_E	333_P	0.531	1.00
308_S	340_S	0.530	1.00
190_W	193_G	0.529	1.00
150_G	301_N	0.529	1.00
429_S	432_L	0.529	1.00
327_V	330_R	0.528	1.00
72_E	384_F	0.527	1.00
323_A	327_V	0.527	1.00
72_E	396_R	0.526	1.00
79_F	222_I	0.526	1.00
375_A	417_L	0.526	1.00
426_M	444_Y	0.526	1.00
13_R	228_D	0.524	1.00
121_W	289_N	0.524	1.00
155_W	158_I	0.524	1.00
97_W	435_V	0.523	1.00
413_M	417_L	0.521	1.00
384_F	389_Q	0.520	1.00
23_I	26_G	0.520	1.00
16_K	147_K	0.517	1.00
29_I	36_G	0.516	1.00
114_V	118_I	0.516	1.00
71_V	396_R	0.515	1.00
244_R	251_G	0.514	1.00
230_P	233_S	0.514	1.00
433_I	440_L	0.514	1.00
231_E	236_K	0.514	1.00
40_V	210_I	0.513	1.00
392_G	396_R	0.512	1.00
256_L	272_F	0.512	1.00
52_Y	253_L	0.511	1.00
39_S	42_Q	0.511	1.00
334_V	337_I	0.511	1.00
220_V	234_I	0.510	1.00
218_E	374_W	0.509	1.00
174_L	177_S	0.508	1.00
52_Y	249_Y	0.508	1.00
104_V	340_S	0.508	1.00
49_I	52_Y	0.507	1.00
175_L	259_L	0.507	1.00
20_I	220_V	0.507	1.00
188_N	192_Q	0.506	1.00
438_I	443_G	0.505	1.00
133_V	136_V	0.504	1.00
102_L	369_A	0.503	1.00
189_L	192_Q	0.501	1.00
227_A	237_A	0.500	1.00
406_N	420_M	0.500	1.00
430_V	439_V	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3l1lA	2	0.9059	100	0.294	Contact Map
4djkA	2	0.8972	100	0.349	Contact Map
3giaA	1	0.9212	100	0.35	Contact Map
3dh4A	3	0.9212	99.2	0.841	Contact Map
2xq2A	2	0.9278	99.1	0.847	Contact Map
2jlnA	1	0.9103	98.8	0.864	Contact Map
4wgvA	2	0.8118	97.7	0.899	Contact Map
2a65A	2	0.9344	97.3	0.907	Contact Map
4xp4A	1	0.9409	97.1	0.91	Contact Map
4us3A	1	0.8731	96.9	0.913	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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