GREMLIN Database
MALQ - 4-alpha-glucanotransferase
UniProt: P15977 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10561
Length: 694 (660)
Sequences: 1145 (799)
Seq/√Len: 31.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
264_R340_D8.4551.00
303_A340_D4.7861.00
214_I350_L4.4761.00
439_M491_C4.4001.00
221_D277_Q4.3431.00
180_S368_P4.3311.00
80_L124_V4.1851.00
44_R50_A4.0931.00
352_Y441_N4.0671.00
320_E323_Q4.0021.00
172_V361_I3.6991.00
426_R430_P3.4901.00
285_V345_L3.4011.00
132_Y486_S3.3821.00
290_D294_W3.3721.00
82_T109_H3.3531.00
562_T580_Y3.3461.00
321_M329_E3.2901.00
146_A174_V3.2111.00
386_T393_Y3.1861.00
280_A353_S3.1521.00
174_V179_G3.1171.00
278_M282_R3.0781.00
165_G215_D3.0711.00
127_A480_S3.0671.00
333_F337_H3.0611.00
295_Q384_A3.0571.00
47_T51_V2.9091.00
360_E364_G2.8671.00
21_N25_K2.8661.00
188_H376_A2.8201.00
352_Y440_Q2.8131.00
429_E433_E2.7551.00
264_R303_A2.7051.00
110_T121_H2.6731.00
144_W179_G2.6351.00
155_S166_D2.6301.00
422_I425_A2.6191.00
78_W90_G2.6101.00
297_A334_C2.5351.00
445_L493_V2.5341.00
7_D34_K2.4740.99
108_Y125_I2.4620.99
158_N166_D2.4540.99
267_W342_D2.4470.99
260_M343_F2.4380.99
305_Q322_Y2.4350.99
588_Q592_D2.4090.99
181_F634_G2.4040.99
458_W471_V2.3220.99
412_N465_A2.2720.99
86_T90_G2.2710.99
18_N26_P2.2570.99
214_I351_A2.2400.99
533_P624_Y2.2320.99
284_F288_Q2.2230.99
13_A43_Q2.2220.99
60_Y126_V2.1960.99
293_F345_L2.1460.98
164_F351_A2.1390.98
593_A624_Y2.0990.98
105_P109_H2.0230.98
281_F345_L2.0220.98
82_T88_Y2.0110.97
643_M664_S2.0000.97
165_G218_A1.9890.97
251_D254_T1.9790.97
183_G372_Y1.9760.97
454_L505_I1.9720.97
112_T121_H1.9700.97
301_L322_Y1.9660.97
39_D45_T1.9570.97
666_T669_S1.9460.97
273_R278_M1.9220.97
79_L112_T1.9170.97
46_A50_A1.9090.97
125_I484_L1.9000.96
451_M501_V1.8950.96
16_S472_H1.8870.96
665_A670_M1.8870.96
439_M493_V1.8820.96
260_M264_R1.8810.96
463_E467_Q1.8780.96
234_L237_T1.8760.96
562_T566_T1.8560.96
152_T647_V1.8530.96
332_Q336_E1.8500.96
542_A630_S1.8500.96
79_L87_Q1.8450.96
432_I436_R1.8320.96
16_S469_A1.7980.95
680_L683_L1.7980.95
352_Y356_A1.7930.95
216_V266_A1.7910.95
35_R45_T1.7690.95
155_S158_N1.7600.94
209_L351_A1.7580.94
45_T51_V1.7510.94
157_K217_N1.7370.94
125_I481_I1.7300.94
304_Q336_E1.6990.93
37_L469_A1.6970.93
281_F342_D1.6860.93
530_F555_Y1.6700.93
456_L473_Y1.6670.93
540_S630_S1.6620.93
83_E488_R1.6450.92
504_E507_G1.6430.92
675_G679_L1.6420.92
61_T511_S1.6400.92
13_A38_L1.6370.92
314_G317_A1.6360.92
219_V350_L1.6330.92
419_D422_I1.6310.92
417_P458_W1.6020.91
164_F187_I1.5940.91
171_L362_S1.5910.91
20_I26_P1.5900.91
212_I256_T1.5870.91
431_F435_L1.5830.91
240_T243_Q1.5820.91
624_Y628_S1.5810.91
163_D259_K1.5800.90
324_N327_S1.5780.90
109_H488_R1.5760.90
652_T655_Q1.5720.90
517_Y543_V1.5660.90
156_E666_T1.5610.90
267_W281_F1.5390.89
256_T260_M1.5370.89
619_R679_L1.5350.89
24_G506_V1.5320.89
565_K574_V1.5250.89
450_V495_G1.5170.89
82_T86_T1.5120.88
519_V543_V1.5100.88
301_L305_Q1.5090.88
181_F632_L1.5060.88
379_V385_E1.4990.88
390_R393_Y1.4960.88
171_L182_I1.4810.87
522_F549_L1.4770.87
372_Y444_A1.4510.86
114_T119_R1.4490.86
106_E484_L1.4490.86
477_D480_S1.4350.86
479_L509_L1.4340.86
615_P678_K1.4330.86
57_V427_A1.4310.85
361_I365_Y1.4300.85
476_D508_K1.4300.85
33_T37_L1.4210.85
619_R678_K1.4190.85
451_M495_G1.4180.85
444_A447_I1.4150.85
61_T480_S1.4150.85
518_K537_P1.4140.85
68_M111_L1.4130.85
431_F481_I1.4070.84
192_P299_D1.4050.84
77_S114_T1.3920.84
15_I471_V1.3710.83
59_V63_G1.3670.83
464_T467_Q1.3640.83
94_G98_F1.3620.82
478_L500_T1.3610.82
52_T425_A1.3570.82
85_G109_H1.3560.82
486_S490_R1.3490.82
18_N28_S1.3460.82
593_A596_K1.3450.82
250_V662_K1.3430.82
427_A430_P1.3420.82
431_F478_L1.3350.81
417_P471_V1.3330.81
156_E669_S1.3290.81
638_E661_R1.3270.81
396_K461_Y1.3170.80
285_V293_F1.3170.80
94_G97_A1.3120.80
156_E668_E1.3110.80
397_A458_W1.3080.80
318_W387_W1.3030.80
413_W648_N1.2930.79
622_Q683_L1.2820.78
54_V59_V1.2780.78
147_C634_G1.2770.78
168_K357_A1.2770.78
44_R48_K1.2730.78
264_R268_K1.2730.78
237_T244_A1.2730.78
485_E488_R1.2700.78
451_M506_V1.2620.77
83_E108_Y1.2600.77
185_N213_Y1.2550.77
432_I477_D1.2520.77
81_T112_T1.2490.77
9_A45_T1.2480.76
373_R442_C1.2460.76
35_R47_T1.2460.76
82_T103_K1.2420.76
300_A333_F1.2400.76
337_H340_D1.2400.76
300_A337_H1.2330.76
149_Q456_L1.2220.75
155_S354_Q1.2210.75
108_Y432_I1.2130.74
170_M667_L1.2120.74
87_Q92_V1.2000.74
8_N11_L1.1970.73
372_Y494_I1.1970.73
285_V342_D1.1940.73
538_E631_A1.1930.73
21_N500_T1.1910.73
533_P593_A1.1900.73
543_V634_G1.1890.73
284_F352_Y1.1880.73
218_A357_A1.1870.73
279_A283_Q1.1860.73
515_Y629_N1.1820.72
215_D218_A1.1810.72
189_A203_P1.1800.72
520_L590_L1.1770.72
177_R677_N1.1770.72
197_S380_A1.1750.72
88_Y103_K1.1710.72
315_W323_Q1.1690.72
399_V456_L1.1690.72
297_A341_V1.1670.71
205_S385_E1.1670.71
480_S483_A1.1660.71
114_T117_D1.1660.71
83_E109_H1.1630.71
551_T554_G1.1630.71
444_A494_I1.1630.71
63_G103_K1.1620.71
374_D496_E1.1610.71
392_L426_R1.1570.71
295_Q299_D1.1540.71
168_K171_L1.1510.70
143_L632_L1.1500.70
225_S229_Q1.1490.70
635_L640_W1.1480.70
524_N586_A1.1470.70
170_M182_I1.1470.70
322_Y329_E1.1410.70
324_N390_R1.1370.69
31_A290_D1.1290.69
424_T477_D1.1290.69
359_W363_Q1.1190.68
478_L481_I1.1190.68
482_L656_Y1.1170.68
196_E253_S1.1150.68
205_S291_S1.1080.67
587_K591_L1.1070.67
73_S76_Y1.1060.67
284_F292_L1.1050.67
367_M370_G1.1030.67
301_L387_W1.1030.67
535_A593_A1.1020.67
493_V683_L1.1020.67
192_P207_R1.0990.67
325_V390_R1.0930.66
57_V123_R1.0900.66
153_L630_S1.0900.66
41_M85_G1.0840.66
58_M122_C1.0800.65
583_R586_A1.0770.65
374_D413_W1.0760.65
154_R451_M1.0750.65
92_V98_F1.0730.65
359_W362_S1.0680.65
675_G678_K1.0660.64
665_A669_S1.0610.64
413_W448_D1.0590.64
322_Y333_F1.0560.64
240_T261_T1.0540.63
187_I355_F1.0530.63
5_R31_A1.0520.63
572_D577_R1.0510.63
171_L365_Y1.0500.63
165_G217_N1.0490.63
72_G94_G1.0460.63
184_L187_I1.0460.63
267_W339_D1.0420.63
87_Q90_G1.0410.62
563_L656_Y1.0390.62
623_R682_D1.0380.62
501_V506_V1.0370.62
148_V170_M1.0370.62
30_S35_R1.0350.62
146_A635_L1.0330.62
201_Y455_R1.0320.62
108_Y488_R1.0300.62
19_Y27_Q1.0290.62
293_F297_A1.0250.61
214_I354_Q1.0240.61
323_Q327_S1.0210.61
647_V661_R1.0210.61
131_C477_D1.0200.61
315_W318_W1.0190.61
132_Y490_R1.0180.61
252_Y298_F1.0170.61
173_D671_F1.0160.61
175_A356_A1.0150.60
304_Q337_H1.0130.60
317_A511_S1.0060.60
394_C471_V1.0060.60
39_D46_A1.0060.60
155_S159_W1.0020.59
82_T105_P0.9990.59
411_Q648_N0.9980.59
134_P492_M0.9940.59
413_W496_E0.9890.58
545_A636_Q0.9890.58
6_L45_T0.9890.58
437_A628_S0.9870.58
413_W449_H0.9860.58
376_A443_G0.9830.58
241_L244_A0.9830.58
86_T89_K0.9790.58
282_R285_V0.9770.58
389_D426_R0.9740.57
374_D648_N0.9730.57
392_L430_P0.9710.57
29_I457_W0.9690.57
448_D648_N0.9680.57
585_L589_G0.9670.57
244_A431_F0.9650.57
252_Y516_S0.9650.57
176_K365_Y0.9630.56
458_W473_Y0.9620.56
297_A330_V0.9610.56
143_L368_P0.9590.56
161_I255_V0.9580.56
457_W679_L0.9560.56
530_F590_L0.9550.56
646_P653_S0.9540.56
615_P619_R0.9520.56
423_I428_Y0.9520.56
8_N459_I0.9520.56
62_S172_V0.9490.55
358_C361_I0.9480.55
592_D596_K0.9440.55
506_V518_K0.9430.55
150_L167_L0.9430.55
56_N466_D0.9420.55
602_K605_G0.9420.55
451_M456_L0.9410.55
588_Q595_H0.9410.55
5_R51_V0.9360.54
180_S406_L0.9360.54
15_I41_M0.9340.54
583_R590_L0.9330.54
374_D498_L0.9310.54
36_R463_E0.9310.54
389_D393_Y0.9310.54
113_L478_L0.9280.54
394_C458_W0.9280.54
180_S366_E0.9260.53
304_Q333_F0.9250.53
108_Y210_N0.9240.53
534_K597_Y0.9230.53
674_D678_K0.9230.53
372_Y517_Y0.9230.53
359_W366_E0.9200.53
413_W498_L0.9170.53
496_E648_N0.9170.53
340_D344_Y0.9150.53
328_P341_V0.9130.52
652_T658_N0.9110.52
411_Q449_H0.9080.52
299_D344_Y0.9060.52
249_W369_I0.9020.52
213_Y259_K0.9020.52
159_W222_F0.9010.51
342_D345_L0.8980.51
601_P616_T0.8970.51
497_D506_V0.8940.51
106_E127_A0.8940.51
521_Y552_L0.8940.51
474_P478_L0.8930.51
549_L628_S0.8920.51
53_P113_L0.8900.51
181_F646_P0.8900.51
379_V417_P0.8900.51
412_N461_Y0.8890.50
439_M489_H0.8890.50
428_Y477_D0.8890.50
541_M634_G0.8880.50
518_K523_E0.8860.50
89_K92_V0.8860.50
194_N197_S0.8860.50
48_K478_L0.8840.50
72_G76_Y0.8810.50
486_S489_H0.8730.49
73_S98_F0.8730.49
426_R429_E0.8710.49
613_M617_L0.8710.49
214_I346_W0.8650.49
41_M451_M0.8650.49
394_C416_P0.8640.48
450_V509_L0.8640.48
328_P332_Q0.8640.48
239_Q243_Q0.8620.48
175_A332_Q0.8610.48
52_T64_K0.8610.48
6_L31_A0.8610.48
250_V287_E0.8590.48
17_P29_I0.8580.48
545_A549_L0.8570.48
554_G646_P0.8530.48
57_V122_C0.8530.48
79_L89_K0.8530.48
638_E647_V0.8500.47
161_I250_V0.8440.47
616_T619_R0.8440.47
281_F284_F0.8420.47
412_N459_I0.8410.47
30_S467_Q0.8380.46
159_W262_A0.8380.46
456_L500_T0.8370.46
416_P505_I0.8360.46
546_T554_G0.8360.46
439_M486_S0.8350.46
452_S455_R0.8340.46
91_H117_D0.8340.46
560_D583_R0.8340.46
329_E332_Q0.8330.46
238_Q241_L0.8320.46
211_V260_M0.8310.46
7_D41_M0.8270.45
144_W210_N0.8270.45
414_G459_I0.8260.45
9_A43_Q0.8240.45
147_C450_V0.8240.45
438_N447_I0.8240.45
390_R395_L0.8220.45
505_I509_L0.8200.45
86_T341_V0.8200.45
495_G509_L0.8180.45
374_D446_R0.8180.45
57_V481_I0.8170.45
65_K99_N0.8170.45
238_Q242_Q0.8160.45
147_C183_G0.8160.45
161_I684_D0.8140.44
556_W587_K0.8130.44
82_T85_G0.8130.44
252_Y372_Y0.8120.44
619_R682_D0.8120.44
519_V542_A0.8110.44
38_L44_R0.8100.44
39_D88_Y0.8090.44
498_L522_F0.8080.44
356_A441_N0.8070.44
80_L88_Y0.8050.44
673_D676_V0.8050.44
645_E662_K0.8030.44
498_L648_N0.8030.44
553_R644_A0.8030.44
478_L561_L0.8010.43
9_A51_V0.8000.43
219_V598_G0.8000.43
225_S228_A0.7980.43
592_D595_H0.7940.43
625_I633_L0.7930.43
9_A42_H0.7930.43
12_A51_V0.7900.43
545_A552_L0.7890.42
223_H324_N0.7890.42
501_V536_Y0.7890.42
532_A535_A0.7870.42
32_E467_Q0.7860.42
449_H648_N0.7860.42
386_T390_R0.7850.42
561_L583_R0.7840.42
25_K465_A0.7830.42
411_Q448_D0.7830.42
54_V70_V0.7820.42
167_L213_Y0.7810.42
282_R342_D0.7790.42
546_T549_L0.7780.42
106_E487_K0.7770.41
246_D333_F0.7770.41
15_I37_L0.7760.41
646_P649_I0.7740.41
600_L620_G0.7730.41
22_A29_I0.7730.41
314_G382_G0.7710.41
415_L649_I0.7700.41
64_K129_K0.7690.41
561_L571_P0.7690.41
374_D411_Q0.7670.41
37_L397_A0.7660.41
454_L475_V0.7660.41
638_E643_M0.7650.41
305_Q312_R0.7650.41
453_M456_L0.7650.41
166_D354_Q0.7630.40
81_T87_Q0.7630.40
17_P469_A0.7630.40
315_W319_P0.7610.40
133_E515_Y0.7610.40
495_G501_V0.7600.40
250_V255_V0.7590.40
374_D448_D0.7590.40
380_A414_G0.7580.40
599_C627_D0.7570.40
41_M70_V0.7560.40
329_E360_E0.7560.40
650_P659_W0.7560.40
259_K430_P0.7550.40
131_C486_S0.7540.40
218_A371_L0.7530.40
446_R496_E0.7510.39
544_A622_Q0.7510.39
516_S537_P0.7510.39
183_G252_Y0.7500.39
536_Y630_S0.7480.39
520_L546_T0.7480.39
262_A266_A0.7480.39
557_E644_A0.7460.39
15_I33_T0.7450.39
282_R286_A0.7440.39
193_A302_H0.7430.39
36_R254_T0.7430.39
11_L102_T0.7410.39
21_N27_Q0.7400.39
263_L343_F0.7390.39
159_W259_K0.7390.39
216_V341_V0.7390.39
394_C417_P0.7380.38
15_I394_C0.7370.38
564_G570_Y0.7350.38
474_P560_D0.7320.38
22_A405_I0.7290.38
336_E339_D0.7280.38
638_E646_P0.7280.38
259_K439_M0.7270.38
402_P446_R0.7270.38
157_K169_A0.7260.38
393_Y416_P0.7240.37
424_T474_P0.7240.37
553_R642_D0.7230.37
656_Y661_R0.7210.37
372_Y516_S0.7200.37
221_D537_P0.7180.37
156_E257_A0.7180.37
207_R385_E0.7180.37
283_Q287_E0.7170.37
452_S625_I0.7160.37
486_S560_D0.7160.37
533_P628_S0.7150.37
423_I430_P0.7150.37
362_S367_M0.7130.37
135_Q139_N0.7120.36
28_S42_H0.7110.36
216_V222_F0.7100.36
61_T129_K0.7100.36
377_V415_L0.7100.36
439_M444_A0.7080.36
600_L604_A0.7070.36
413_W446_R0.7050.36
212_I257_A0.7050.36
506_V509_L0.7050.36
412_N653_S0.7030.36
16_S452_S0.7020.36
151_Y377_V0.7020.36
459_I632_L0.7020.36
187_I242_Q0.7020.36
158_N183_G0.7000.36
150_L569_L0.6990.36
268_K335_E0.6990.36
55_P59_V0.6970.35
64_K116_D0.6960.35
591_L601_P0.6960.35
54_V74_G0.6960.35
373_R438_N0.6930.35
254_T526_H0.6920.35
355_F492_M0.6910.35
558_C587_K0.6910.35
349_W495_G0.6900.35
29_I490_R0.6880.35
70_V399_V0.6880.35
158_N662_K0.6880.35
237_T241_L0.6870.35
242_Q246_D0.6870.35
465_A628_S0.6860.35
504_E628_S0.6860.35
183_G636_Q0.6850.34
374_D547_H0.6850.34
161_I398_S0.6850.34
303_A344_Y0.6840.34
128_P484_L0.6840.34
47_T50_A0.6840.34
548_D648_N0.6830.34
134_P515_Y0.6830.34
318_W634_G0.6820.34
294_W334_C0.6800.34
380_A383_G0.6790.34
559_G645_E0.6790.34
253_S256_T0.6790.34
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171_L358_C0.6780.34
158_N372_Y0.6770.34
438_N445_L0.6770.34
447_I631_A0.6760.34
166_D471_V0.6760.34
142_K170_M0.6750.34
413_W548_D0.6750.34
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327_S330_V0.6730.34
591_L595_H0.6720.34
205_S437_A0.6710.33
174_V182_I0.6710.33
394_C419_D0.6710.33
365_Y668_E0.6710.33
148_V619_R0.6690.33
81_T86_T0.6690.33
411_Q496_E0.6690.33
572_D582_D0.6690.33
91_H99_N0.6670.33
85_G88_Y0.6650.33
481_I488_R0.6650.33
304_Q322_Y0.6650.33
260_M483_A0.6640.33
158_N516_S0.6630.33
450_V493_V0.6620.33
126_V478_L0.6610.33
202_S348_Q0.6610.33
191_Y383_G0.6610.33
453_M482_L0.6600.33
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339_D464_T0.6590.33
540_S684_D0.6590.33
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525_D535_A0.6500.32
142_K390_R0.6500.32
634_G646_P0.6500.32
378_G455_R0.6490.32
213_Y481_I0.6470.32
601_P604_A0.6470.32
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174_V671_F0.6450.32
289_G292_L0.6440.32
278_M445_L0.6440.32
35_R41_M0.6440.32
198_A655_Q0.6420.31
552_L583_R0.6420.31
327_S654_Y0.6390.31
281_F349_W0.6390.31
128_P485_E0.6380.31
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436_R484_L0.6370.31
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219_V266_A0.6360.31
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402_P496_E0.6350.31
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243_Q247_A0.6330.31
676_V680_L0.6330.31
268_K342_D0.6320.31
44_R437_A0.6320.31
201_Y402_P0.6320.31
22_A148_V0.6310.31
334_C337_H0.6300.31
636_Q643_M0.6290.31
496_E547_H0.6290.31
669_S685_R0.6280.30
375_L445_L0.6280.30
524_N589_G0.6280.30
312_R315_W0.6280.30
411_Q498_L0.6270.30
80_L83_E0.6250.30
268_K339_D0.6250.30
211_V347_L0.6250.30
76_Y113_L0.6240.30
185_N428_Y0.6230.30
149_Q377_V0.6220.30
86_T92_V0.6220.30
243_Q246_D0.6220.30
320_E335_E0.6210.30
88_Y93_T0.6210.30
479_L514_V0.6210.30
477_D486_S0.6210.30
188_H203_P0.6210.30
159_W166_D0.6200.30
252_Y354_Q0.6190.30
622_Q635_L0.6190.30
35_R48_K0.6190.30
55_P122_C0.6180.30
159_W245_R0.6180.30
171_L174_V0.6170.30
623_R685_R0.6170.30
33_T440_Q0.6160.30
245_R372_Y0.6160.30
201_Y446_R0.6150.30
536_Y542_A0.6150.30
23_H501_V0.6150.30
550_P621_L0.6150.30
239_Q592_D0.6140.30
563_L646_P0.6130.29
544_A621_L0.6130.29
130_R513_G0.6120.29
53_P112_T0.6120.29
30_S463_E0.6100.29
88_Y92_V0.6100.29
372_Y457_W0.6100.29
108_Y337_H0.6100.29
397_A459_I0.6090.29
397_A494_I0.6090.29
386_T389_D0.6080.29
255_V301_L0.6080.29
581_Q585_L0.6070.29
147_C380_A0.6070.29
62_S106_E0.6060.29
583_R638_E0.6060.29
104_L541_M0.6040.29
61_T112_T0.6040.29
448_D498_L0.6040.29
321_M326_D0.6030.29
552_L556_W0.6020.29
5_R8_N0.6010.29
254_T565_K0.6010.29
175_A323_Q0.6010.29
32_E35_R0.6000.29
544_A636_Q0.6000.29
439_M560_D0.5990.29
184_L371_L0.5990.29
65_K70_V0.5990.29
155_S160_G0.5980.28
379_V430_P0.5980.28
151_Y185_N0.5980.28
600_L603_R0.5980.28
448_D496_E0.5970.28
33_T460_P0.5960.28
289_G349_W0.5960.28
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171_L572_D0.5910.28
273_R349_W0.5910.28
414_G500_T0.5910.28
190_L560_D0.5890.28
524_N529_T0.5870.28
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172_V248_D0.5840.28
381_E541_M0.5830.27
459_I589_G0.5830.27
39_D44_R0.5830.27
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304_Q422_I0.5810.27
63_G129_K0.5810.27
451_M594_L0.5800.27
155_S471_V0.5800.27
402_P413_W0.5790.27
547_H648_N0.5780.27
159_W354_Q0.5780.27
300_A344_Y0.5770.27
31_A41_M0.5770.27
358_C441_N0.5770.27
379_V386_T0.5760.27
214_I284_F0.5750.27
78_W255_V0.5750.27
244_A254_T0.5740.27
455_R509_L0.5740.27
331_R476_D0.5730.27
536_Y590_L0.5730.27
206_R420_P0.5720.27
55_P68_M0.5720.27
413_W547_H0.5720.27
111_L462_G0.5720.27
216_V347_L0.5710.27
643_M662_K0.5710.27
253_S662_K0.5710.27
418_M458_W0.5710.27
226_E229_Q0.5700.27
154_R348_Q0.5700.27
446_R648_N0.5700.27
409_L569_L0.5700.27
648_N659_W0.5700.27
84_E105_P0.5690.27
598_G625_I0.5690.27
185_N376_A0.5680.27
539_Q631_A0.5680.27
65_K79_L0.5680.27
528_K565_K0.5660.26
257_A369_I0.5660.26
290_D293_F0.5660.26
486_S491_C0.5660.26
573_E576_L0.5660.26
374_D449_H0.5660.26
190_L372_Y0.5650.26
276_E284_F0.5650.26
73_S94_G0.5640.26
164_F481_I0.5640.26
144_W387_W0.5640.26
567_L570_Y0.5630.26
475_V508_K0.5630.26
188_H367_M0.5610.26
131_C556_W0.5610.26
125_I625_I0.5610.26
337_H369_I0.5610.26
50_A478_L0.5600.26
220_E385_E0.5600.26
357_A601_P0.5600.26
446_R498_L0.5590.26
531_R628_S0.5590.26
411_Q547_H0.5590.26
253_S298_F0.5580.26
132_Y487_K0.5580.26
191_Y583_R0.5570.26
207_R288_Q0.5570.26
91_H236_T0.5570.26
60_Y135_Q0.5570.26
241_L258_L0.5570.26
121_H321_M0.5560.26
35_R46_A0.5560.26
172_V603_R0.5550.26
438_N636_Q0.5550.26
192_P388_C0.5540.26
172_V176_K0.5540.26
369_I632_L0.5540.26
23_H26_P0.5540.26
34_K632_L0.5540.26
30_S33_T0.5530.26
144_W635_L0.5530.26
203_P443_G0.5530.26
75_E79_L0.5530.26
379_V416_P0.5530.26
362_S365_Y0.5520.26
183_G191_Y0.5510.25
108_Y481_I0.5510.25
159_W277_Q0.5510.25
31_A219_V0.5500.25
76_Y98_F0.5490.25
324_N360_E0.5490.25
538_E603_R0.5480.25
212_I255_V0.5480.25
618_N679_L0.5470.25
580_Y584_E0.5470.25
351_A519_V0.5470.25
259_K354_Q0.5470.25
152_T638_E0.5460.25
45_T50_A0.5460.25
67_P97_A0.5450.25
59_V238_Q0.5450.25
515_Y545_A0.5440.25
74_G129_K0.5440.25
166_D259_K0.5430.25
398_S459_I0.5430.25
166_D667_L0.5430.25
481_I485_E0.5420.25
12_A620_G0.5420.25
519_V540_S0.5420.25
500_T522_F0.5420.25
201_Y374_D0.5420.25
654_Y660_R0.5410.25
285_V483_A0.5410.25
404_D496_E0.5410.25
214_I392_L0.5410.25
202_S551_T0.5410.25
70_V73_S0.5410.25
377_V652_T0.5410.25
351_A494_I0.5400.25
584_E616_T0.5390.25
293_F334_C0.5380.25
573_E577_R0.5380.25
178_G206_R0.5380.25
436_R485_E0.5370.25
423_I577_R0.5360.25
405_I524_N0.5360.25
199_S413_W0.5350.24
202_S415_L0.5350.24
90_G100_L0.5340.24
334_C634_G0.5340.24
268_K422_I0.5340.24
229_Q239_Q0.5330.24
244_A368_P0.5330.24
110_T562_T0.5320.24
195_P213_Y0.5310.24
351_A502_P0.5300.24
145_G420_P0.5300.24
149_Q185_N0.5300.24
164_F275_D0.5290.24
389_D392_L0.5290.24
275_D279_A0.5290.24
393_Y505_I0.5290.24
204_S350_L0.5270.24
78_W98_F0.5270.24
252_Y517_Y0.5270.24
80_L336_E0.5260.24
74_G116_D0.5260.24
406_L564_G0.5260.24
225_S516_S0.5250.24
257_A493_V0.5250.24
318_W660_R0.5250.24
108_Y554_G0.5240.24
218_A283_Q0.5240.24
486_S516_S0.5240.24
359_W516_S0.5230.24
28_S84_E0.5230.24
149_Q399_V0.5220.24
267_W667_L0.5220.24
242_Q585_L0.5220.24
123_R459_I0.5220.24
41_M427_A0.5220.24
198_A253_S0.5220.24
381_E414_G0.5220.24
175_A365_Y0.5210.24
49_V282_R0.5210.24
96_K102_T0.5210.24
261_T510_R0.5200.24
125_I134_P0.5190.24
455_R470_Y0.5190.24
167_L184_L0.5190.24
446_R449_H0.5180.23
236_T239_Q0.5180.23
603_R620_G0.5170.23
158_N633_L0.5160.23
41_M419_D0.5160.23
681_K685_R0.5150.23
74_G371_L0.5150.23
335_E685_R0.5150.23
183_G517_Y0.5150.23
335_E681_K0.5140.23
287_E440_Q0.5140.23
11_L29_I0.5140.23
444_A465_A0.5140.23
159_W221_D0.5130.23
318_W504_E0.5130.23
622_Q640_W0.5130.23
64_K511_S0.5130.23
595_H620_G0.5130.23
114_T514_V0.5120.23
638_E641_L0.5120.23
197_S486_S0.5110.23
75_E602_K0.5110.23
339_D342_D0.5110.23
617_L681_K0.5110.23
252_Y662_K0.5110.23
7_D31_A0.5100.23
179_G367_M0.5100.23
359_W457_W0.5100.23
108_Y556_W0.5090.23
228_A323_Q0.5090.23
182_I459_I0.5090.23
201_Y547_H0.5070.23
446_R547_H0.5060.23
242_Q602_K0.5060.23
69_V433_E0.5060.23
615_P675_G0.5060.23
33_T459_I0.5060.23
457_W543_V0.5050.23
647_V664_S0.5040.23
295_Q348_Q0.5030.23
375_L447_I0.5030.23
41_M471_V0.5030.23
165_G261_T0.5020.23
84_E248_D0.5020.23
433_E436_R0.5020.23
293_F476_D0.5010.23
178_G355_F0.5010.23
641_L647_V0.5000.22
518_K551_T0.5000.22
637_P666_T0.5000.22
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4s3qA 1 0.987 100 0.168 Contact Map
1eswA 1 0.7003 100 0.421 Contact Map
1x1nA 2 0.7305 100 0.421 Contact Map
1tz7A 4 0.6888 100 0.426 Contact Map
4bzyA 1 0.6686 97 0.97 Contact Map
1ht6A 1 0.5086 96 0.973 Contact Map
1ud2A 1 0.4885 95.7 0.974 Contact Map
4e2oA 1 0.4741 95.1 0.975 Contact Map
3edfA 2 0.6239 94.4 0.976 Contact Map
3amlA 1 0.7118 93.8 0.976 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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