PUR2 - ECOLI - GREMLIN Contacts

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PUR2 - Phosphoribosylamine--glycine ligase

UniProt:	P15640	Sequences: MKVLVIGNGGREHALAWKAAQSPLVETVFVAPGNAGTALEPALQNVAIGVTDIPALLDFAQNEKIDLTIVGPEAPLVKGVVDTFRAAGLKIFGPTAGAAQLEGSKAFTKDFLARHKIPTAEYQNFTEVEPALAYLREKGAPIVIKADGLAAGKGVIVAMTLEEAEAAVHDMLAGNAFGDAGHRIVIEEFLDGEEASFIVMVDGEHVLPMATSQDHKRVGDKDTGPNTGGMGAYSPAPVVTDDVHQRTMERIIWPTVKGMAAEGNTYTGFLYAGLMIDKQGNPKVIEFNCRFGDPETQPIMLRMKSDLVELCLAACESKLDEKTSEWDERASLGVVMAAGGYPGDYRTGDVIHGLPLEEVAGGKVFHAGTKLADDEQVVTNGGRVLCVTALGHTVAEAQKRAYALMTDIHWDDCFCRKDIGWRAIEREQN	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10792
Length:	429 (382)
Sequences:	20925 (11624)
Seq/√Len:	594.7

ECOLI - PUR2 ACCC PURT PURK DDLB CARB
BACSU - PUR2 ACCC1 ACCC2 BACD PURT PURK DDL PYC
HALSA - Q9HQ67 Q9HRM3 Q9HPP8 CARB
SULSO - Q7LXR2 Q97VY6 PURT PURK

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
136_R	161_L	3.995	1.00
132_L	165_E	3.326	1.00
160_T	163_E	3.281	1.00
121_E	188_E	3.205	1.00
58_D	62_N	3.183	1.00
127_E	130_P	3.086	1.00
253_W	257_K	3.025	1.00
250_R	254_P	2.892	1.00
52_D	55_A	2.780	1.00
82_D	100_Q	2.724	1.00
140_A	161_L	2.663	1.00
393_T	396_E	2.645	1.00
82_D	86_A	2.600	1.00
246_R	250_R	2.526	1.00
391_G	396_E	2.478	1.00
159_M	163_E	2.363	1.00
114_R	258_G	2.335	1.00
61_Q	87_A	2.271	1.00
112_L	255_T	2.226	1.00
123_Q	137_E	2.223	1.00
27_T	44_Q	2.190	1.00
241_D	245_Q	2.142	1.00
77_V	103_G	2.108	1.00
240_T	243_V	2.093	1.00
83_T	87_A	2.056	1.00
203_G	267_T	2.046	1.00
110_D	114_R	2.016	1.00
309_E	313_A	2.012	1.00
134_Y	137_E	2.002	1.00
234_S	302_R	1.979	1.00
107_F	110_D	1.971	1.00
5_V	16_A	1.954	1.00
277_D	280_G	1.942	1.00
161_L	165_E	1.940	1.00
251_I	282_P	1.931	1.00
191_D	278_K	1.926	1.00
157_V	189_F	1.900	1.00
392_H	396_E	1.883	1.00
159_M	191_D	1.879	1.00
128_V	165_E	1.844	1.00
53_I	83_T	1.830	1.00
19_A	28_V	1.826	1.00
3_V	92_F	1.824	1.00
134_Y	138_K	1.808	1.00
304_K	325_E	1.768	1.00
57_L	87_A	1.758	1.00
57_L	61_Q	1.742	1.00
128_V	169_H	1.734	1.00
24_L	309_E	1.734	1.00
334_V	401_A	1.733	1.00
165_E	169_H	1.731	1.00
100_Q	107_F	1.728	1.00
111_F	258_G	1.713	1.00
128_V	132_L	1.701	1.00
55_A	58_D	1.700	1.00
132_L	161_L	1.693	1.00
350_V	376_Q	1.692	1.00
110_D	113_A	1.691	1.00
27_T	45_N	1.673	1.00
4_L	31_A	1.672	1.00
95_T	98_A	1.654	1.00
115_H	258_G	1.644	1.00
243_V	246_R	1.627	1.00
304_K	327_D	1.614	1.00
366_H	369_T	1.604	1.00
101_L	111_F	1.603	1.00
85_R	96_A	1.592	1.00
172_L	182_H	1.577	1.00
133_A	137_E	1.576	1.00
200_M	310_L	1.561	1.00
13_H	42_A	1.561	1.00
245_Q	250_R	1.552	1.00
166_A	170_D	1.548	1.00
106_A	124_N	1.533	1.00
199_V	252_I	1.532	1.00
83_T	86_A	1.519	1.00
68_T	89_L	1.519	1.00
24_L	312_L	1.513	1.00
30_V	43_L	1.510	1.00
18_K	309_E	1.507	1.00
245_Q	248_M	1.497	1.00
243_V	276_I	1.496	1.00
37_T	45_N	1.496	1.00
34_N	48_I	1.492	1.00
58_D	61_Q	1.488	1.00
200_M	269_F	1.483	1.00
106_A	110_D	1.483	1.00
254_P	257_K	1.480	1.00
54_P	83_T	1.478	1.00
101_L	107_F	1.466	1.00
132_L	136_R	1.456	1.00
84_F	89_L	1.452	1.00
111_F	114_R	1.452	1.00
142_I	186_I	1.452	1.00
147_D	183_R	1.449	1.00
318_K	321_E	1.447	1.00
53_I	57_L	1.445	1.00
310_L	320_D	1.443	1.00
370_K	373_D	1.441	1.00
20_A	44_Q	1.437	1.00
59_F	63_E	1.429	1.00
197_F	247_T	1.407	1.00
85_R	95_T	1.406	1.00
111_F	115_H	1.403	1.00
126_T	130_P	1.402	1.00
123_Q	134_Y	1.402	1.00
3_V	19_A	1.395	1.00
200_M	314_A	1.394	1.00
97_G	101_L	1.390	1.00
403_A	407_D	1.386	1.00
135_L	140_A	1.384	1.00
109_K	187_E	1.368	1.00
301_L	388_T	1.365	1.00
346_R	349_D	1.363	1.00
129_E	133_A	1.352	1.00
130_P	133_A	1.339	1.00
188_E	283_K	1.329	1.00
244_H	248_M	1.329	1.00
301_L	390_L	1.329	1.00
248_M	253_W	1.326	1.00
133_A	136_R	1.325	1.00
126_T	183_R	1.323	1.00
199_V	256_V	1.320	1.00
128_V	168_V	1.319	1.00
113_A	121_E	1.314	1.00
104_S	147_D	1.309	1.00
90_K	316_E	1.309	1.00
190_L	285_I	1.295	1.00
135_L	142_I	1.295	1.00
125_F	134_Y	1.295	1.00
395_A	399_K	1.287	1.00
60_A	89_L	1.279	1.00
246_R	280_G	1.275	1.00
45_N	63_E	1.265	1.00
402_Y	406_T	1.257	1.00
16_A	42_A	1.251	1.00
169_H	173_A	1.242	1.00
108_T	112_L	1.242	1.00
252_I	272_A	1.237	1.00
201_V	256_V	1.229	1.00
319_L	322_K	1.224	1.00
140_A	160_T	1.221	1.00
26_E	316_E	1.220	1.00
23_P	309_E	1.220	1.00
396_E	400_R	1.218	1.00
129_E	132_L	1.213	1.00
242_D	246_R	1.212	1.00
362_G	389_A	1.211	1.00
110_D	122_Y	1.211	1.00
102_E	287_F	1.209	1.00
372_A	376_Q	1.207	1.00
195_A	276_I	1.206	1.00
350_V	375_E	1.192	1.00
118_P	251_I	1.190	1.00
201_V	207_L	1.189	1.00
124_N	183_R	1.184	1.00
82_D	97_G	1.176	1.00
84_F	91_I	1.174	1.00
112_L	284_V	1.173	1.00
166_A	169_H	1.162	1.00
359_V	362_G	1.160	1.00
333_G	386_C	1.159	1.00
361_G	400_R	1.157	1.00
143_V	157_V	1.156	1.00
337_A	382_G	1.147	1.00
391_G	400_R	1.146	1.00
71_G	75_P	1.144	1.00
24_L	313_A	1.142	1.00
329_R	390_L	1.141	1.00
3_V	26_E	1.140	1.00
333_G	336_M	1.138	1.00
330_A	333_G	1.131	1.00
391_G	397_A	1.130	1.00
241_D	244_H	1.127	1.00
199_V	272_A	1.127	1.00
109_K	119_T	1.126	1.00
113_A	119_T	1.115	1.00
398_Q	402_Y	1.109	1.00
95_T	267_T	1.098	1.00
60_A	68_T	1.095	1.00
163_E	166_A	1.088	1.00
291_F	307_L	1.085	1.00
389_A	401_A	1.084	1.00
192_G	278_K	1.081	1.00
305_S	310_L	1.078	1.00
4_L	60_A	1.078	1.00
77_V	80_V	1.075	1.00
239_V	243_V	1.074	1.00
156_I	171_M	1.074	1.00
156_I	170_D	1.073	1.00
106_A	147_D	1.073	1.00
329_R	392_H	1.069	1.00
313_A	318_K	1.066	1.00
121_E	138_K	1.057	1.00
387_V	408_I	1.049	1.00
400_R	403_A	1.047	1.00
3_V	312_L	1.047	1.00
16_A	28_V	1.046	1.00
362_G	404_L	1.038	1.00
31_A	56_L	1.037	1.00
32_P	37_T	1.025	1.00
207_L	253_W	1.023	1.00
143_V	189_F	1.019	1.00
57_L	83_T	1.014	1.00
387_V	404_L	1.013	1.00
399_K	403_A	1.009	1.00
310_L	313_A	1.005	1.00
68_T	84_F	1.000	1.00
156_I	167_A	0.994	1.00
128_V	172_L	0.994	1.00
138_K	142_I	0.993	1.00
41_P	370_K	0.990	1.00
168_V	172_L	0.988	1.00
199_V	270_L	0.985	1.00
336_M	405_M	0.981	1.00
97_G	100_Q	0.980	1.00
197_F	252_I	0.979	1.00
403_A	406_T	0.977	1.00
15_L	69_I	0.977	1.00
32_P	46_V	0.976	1.00
191_D	277_D	0.974	1.00
197_F	248_M	0.972	1.00
29_F	63_E	0.967	1.00
16_A	43_L	0.965	1.00
113_A	122_Y	0.963	1.00
140_A	164_A	0.958	1.00
238_V	276_I	0.955	1.00
136_R	165_E	0.954	1.00
276_I	282_P	0.950	1.00
90_K	203_G	0.950	1.00
208_P	321_E	0.949	1.00
162_E	166_A	0.947	1.00
31_A	49_G	0.947	1.00
332_L	398_Q	0.947	1.00
85_R	267_T	0.943	1.00
80_V	84_F	0.938	1.00
272_A	287_F	0.937	1.00
255_T	287_F	0.934	1.00
369_T	373_D	0.933	1.00
204_E	318_K	0.928	1.00
130_P	134_Y	0.927	1.00
54_P	58_D	0.927	1.00
252_I	274_L	0.924	1.00
201_V	206_V	0.922	1.00
144_I	184_I	0.921	1.00
331_S	334_V	0.919	1.00
113_A	123_Q	0.917	1.00
204_E	317_S	0.915	1.00
333_G	337_A	0.913	1.00
331_S	336_M	0.909	1.00
121_E	137_E	0.909	1.00
19_A	312_L	0.909	1.00
389_A	404_L	0.908	1.00
201_V	257_K	0.905	1.00
351_I	369_T	0.904	1.00
211_T	214_D	0.903	1.00
312_L	316_E	0.903	1.00
209_M	248_M	0.901	1.00
300_M	388_T	0.893	1.00
82_D	96_A	0.887	1.00
246_R	251_I	0.886	1.00
242_D	245_Q	0.885	1.00
47_A	63_E	0.882	1.00
81_V	91_I	0.881	1.00
206_V	257_K	0.880	1.00
74_A	78_K	0.877	1.00
240_T	280_G	0.872	1.00
131_A	164_A	0.867	1.00
148_G	181_G	0.866	1.00
135_L	164_A	0.864	1.00
162_E	165_E	0.863	1.00
95_T	265_T	0.859	1.00
131_A	168_V	0.857	1.00
20_A	42_A	0.857	1.00
404_L	407_D	0.856	1.00
168_V	184_I	0.853	1.00
329_R	333_G	0.852	1.00
338_A	341_Y	0.848	1.00
334_V	337_A	0.847	1.00
5_V	19_A	0.846	1.00
3_V	25_V	0.841	1.00
69_I	311_C	0.841	1.00
335_V	338_A	0.838	1.00
251_I	274_L	0.833	1.00
246_R	282_P	0.829	1.00
332_L	397_A	0.825	1.00
212_S	244_H	0.825	1.00
364_V	385_L	0.824	1.00
59_F	65_I	0.824	1.00
34_N	37_T	0.822	1.00
233_Y	394_V	0.819	1.00
205_H	257_K	0.819	1.00
190_L	283_K	0.819	1.00
117_I	284_V	0.814	1.00
82_D	85_R	0.810	1.00
81_V	85_R	0.809	1.00
143_V	155_V	0.809	1.00
193_E	276_I	0.804	1.00
20_A	28_V	0.802	1.00
142_I	158_A	0.801	1.00
144_I	158_A	0.801	1.00
79_G	83_T	0.800	1.00
106_A	183_R	0.799	1.00
102_E	259_M	0.796	1.00
396_E	399_K	0.794	1.00
125_F	131_A	0.794	1.00
56_L	84_F	0.789	1.00
202_D	206_V	0.788	1.00
330_A	335_V	0.787	1.00
332_L	335_V	0.787	1.00
352_H	355_P	0.786	1.00
256_V	270_L	0.786	1.00
247_T	282_P	0.786	1.00
318_K	322_K	0.785	1.00
170_D	174_G	0.784	1.00
206_V	256_V	0.783	1.00
158_A	167_A	0.782	1.00
73_E	76_L	0.780	1.00
92_F	312_L	0.780	1.00
29_F	59_F	0.778	1.00
337_A	341_Y	0.774	1.00
19_A	69_I	0.774	1.00
85_R	97_G	0.773	1.00
354_L	408_I	0.768	1.00
275_M	285_I	0.767	1.00
78_K	100_Q	0.767	1.00
57_L	86_A	0.763	1.00
331_S	335_V	0.763	1.00
29_F	65_I	0.761	1.00
367_A	370_K	0.761	1.00
104_S	183_R	0.757	1.00
79_G	100_Q	0.757	1.00
47_A	59_F	0.753	1.00
353_G	409_H	0.750	1.00
132_L	169_H	0.744	1.00
84_F	87_A	0.744	1.00
267_T	314_A	0.744	1.00
123_Q	130_P	0.740	1.00
79_G	82_D	0.740	1.00
234_S	298_P	0.737	1.00
254_P	258_G	0.731	1.00
389_A	397_A	0.728	1.00
179_D	182_H	0.727	1.00
53_I	80_V	0.725	1.00
98_A	265_T	0.722	1.00
311_C	315_C	0.721	1.00
135_L	139_G	0.720	1.00
34_N	47_A	0.718	1.00
110_D	124_N	0.717	1.00
60_A	84_F	0.716	1.00
328_E	392_H	0.711	1.00
156_I	174_G	0.710	1.00
170_D	173_A	0.710	1.00
255_T	258_G	0.709	1.00
395_A	398_Q	0.709	1.00
144_I	168_V	0.709	1.00
344_D	347_T	0.708	1.00
48_I	55_A	0.707	1.00
144_I	167_A	0.707	1.00
106_A	185_V	0.700	1.00
78_K	81_V	0.700	1.00
286_E	290_R	0.697	1.00
329_R	332_L	0.696	1.00
72_P	76_L	0.695	1.00
104_S	148_G	0.695	1.00
209_M	214_D	0.694	1.00
13_H	40_E	0.692	1.00
351_I	354_L	0.690	1.00
131_A	186_I	0.689	1.00
210_A	303_M	0.688	1.00
190_L	277_D	0.685	1.00
367_A	372_A	0.685	1.00
128_V	131_A	0.684	1.00
378_V	381_G	0.682	1.00
310_L	321_E	0.681	1.00
77_V	81_V	0.675	1.00
128_V	164_A	0.674	1.00
210_A	234_S	0.673	1.00
6_I	80_V	0.672	1.00
332_L	337_A	0.671	1.00
195_A	247_T	0.670	1.00
205_H	320_D	0.669	1.00
72_P	75_P	0.669	1.00
368_G	371_L	0.666	1.00
212_S	236_A	0.660	1.00
107_F	111_F	0.660	1.00
359_V	400_R	0.660	1.00
19_A	26_E	0.658	1.00
200_M	209_M	0.657	1.00
201_V	267_T	0.657	1.00
116_K	254_P	0.655	1.00
350_V	353_G	0.654	1.00
239_V	244_H	0.652	1.00
85_R	91_I	0.651	1.00
211_T	326_W	0.650	1.00
198_I	269_F	0.650	1.00
104_S	107_F	0.649	1.00
375_E	378_V	0.648	1.00
193_E	238_V	0.648	1.00
358_E	361_G	0.646	1.00
16_A	30_V	0.645	1.00
138_K	188_E	0.645	1.00
352_H	397_A	0.644	1.00
98_A	267_T	0.643	1.00
195_A	236_A	0.642	1.00
330_A	334_V	0.642	1.00
276_I	279_Q	0.641	1.00
368_G	373_D	0.640	1.00
328_E	390_L	0.640	1.00
90_K	267_T	0.638	1.00
158_A	164_A	0.638	1.00
277_D	283_K	0.638	1.00
135_L	168_V	0.636	1.00
252_I	256_V	0.634	1.00
67_L	315_C	0.633	1.00
385_L	408_I	0.632	1.00
372_A	378_V	0.631	1.00
369_T	372_A	0.628	1.00
338_A	349_D	0.626	1.00
266_Y	270_L	0.623	1.00
355_P	409_H	0.623	1.00
232_A	298_P	0.621	1.00
171_M	184_I	0.621	1.00
336_M	408_I	0.620	1.00
323_T	326_W	0.620	1.00
210_A	214_D	0.620	1.00
167_A	171_M	0.619	1.00
359_V	407_D	0.618	1.00
211_T	302_R	0.616	1.00
224_G	229_G	0.616	1.00
197_F	212_S	0.615	1.00
210_A	302_R	0.614	1.00
212_S	215_H	0.613	1.00
229_G	232_A	0.612	1.00
134_Y	186_I	0.612	1.00
81_V	84_F	0.612	1.00
246_R	254_P	0.610	1.00
26_E	66_D	0.610	1.00
96_A	100_Q	0.609	1.00
147_D	185_V	0.608	1.00
42_A	45_N	0.606	1.00
251_I	254_P	0.606	1.00
352_H	409_H	0.604	1.00
18_K	24_L	0.604	1.00
55_A	59_F	0.602	1.00
3_V	28_V	0.600	1.00
30_V	37_T	0.600	1.00
360_A	363_K	0.600	1.00
195_A	239_V	0.600	1.00
355_P	371_L	0.599	1.00
197_F	274_L	0.597	1.00
353_G	371_L	0.596	1.00
350_V	354_L	0.595	1.00
135_L	138_K	0.595	1.00
90_K	93_G	0.593	1.00
29_F	46_V	0.591	1.00
213_Q	233_Y	0.591	1.00
57_L	89_L	0.591	1.00
368_G	372_A	0.591	1.00
243_V	280_G	0.589	1.00
279_Q	283_K	0.587	1.00
243_V	282_P	0.587	1.00
361_G	364_V	0.586	1.00
321_E	325_E	0.585	1.00
109_K	120_A	0.583	1.00
349_D	353_G	0.583	1.00
339_G	346_R	0.582	1.00
330_A	394_V	0.581	1.00
25_V	308_V	0.580	1.00
101_L	114_R	0.578	1.00
195_A	274_L	0.578	1.00
300_M	306_D	0.577	1.00
401_A	405_M	0.577	1.00
204_E	257_K	0.576	1.00
366_H	371_L	0.576	1.00
259_M	265_T	0.575	1.00
231_G	334_V	0.573	1.00
337_A	340_G	0.573	1.00
105_K	145_K	0.573	1.00
61_Q	86_A	0.571	1.00
297_Q	300_M	0.571	1.00
136_R	140_A	0.571	1.00
60_A	65_I	0.570	1.00
157_V	227_T	0.569	1.00
49_G	52_D	0.568	1.00
172_L	184_I	0.567	1.00
214_D	236_A	0.567	1.00
92_F	315_C	0.567	1.00
48_I	59_F	0.564	1.00
397_A	401_A	0.563	1.00
301_L	363_K	0.561	1.00
167_A	170_D	0.558	0.99
202_D	317_S	0.556	0.99
324_S	327_D	0.553	0.99
276_I	280_G	0.552	0.99
211_T	215_H	0.551	0.99
117_I	251_I	0.550	0.99
153_K	174_G	0.549	0.99
354_L	377_V	0.548	0.99
58_D	87_A	0.547	0.99
159_M	189_F	0.546	0.99
112_L	117_I	0.543	0.99
25_V	28_V	0.541	0.99
109_K	113_A	0.541	0.99
364_V	408_I	0.540	0.99
406_T	409_H	0.539	0.99
118_P	283_K	0.538	0.99
188_E	277_D	0.537	0.99
4_L	65_I	0.536	0.99
333_G	338_A	0.535	0.99
307_L	311_C	0.534	0.99
68_T	91_I	0.533	0.99
332_L	336_M	0.533	0.99
272_A	284_V	0.533	0.99
210_A	213_Q	0.533	0.99
359_V	363_K	0.533	0.99
329_R	335_V	0.531	0.99
329_R	334_V	0.530	0.99
35_A	377_V	0.530	0.99
345_Y	348_G	0.529	0.99
144_I	164_A	0.529	0.99
202_D	319_L	0.529	0.99
240_T	276_I	0.528	0.99
209_M	253_W	0.528	0.99
370_K	378_V	0.527	0.99
250_R	253_W	0.526	0.99
255_T	284_V	0.526	0.99
364_V	367_A	0.525	0.99
394_V	398_Q	0.525	0.99
312_L	315_C	0.524	0.99
74_A	77_V	0.523	0.99
213_Q	236_A	0.522	0.99
330_A	393_T	0.522	0.99
310_L	322_K	0.522	0.99
97_G	107_F	0.521	0.99
139_G	161_L	0.520	0.99
373_D	376_Q	0.519	0.99
71_G	76_L	0.519	0.99
198_I	212_S	0.519	0.99
310_L	314_A	0.518	0.99
144_I	186_I	0.518	0.99
204_E	267_T	0.518	0.99
163_E	167_A	0.517	0.99
56_L	68_T	0.516	0.99
347_T	350_V	0.516	0.99
17_W	23_P	0.515	0.99
132_L	164_A	0.515	0.99
120_A	285_I	0.515	0.99
208_P	248_M	0.515	0.99
41_P	44_Q	0.514	0.99
366_H	373_D	0.514	0.99
269_F	291_F	0.514	0.99
46_V	59_F	0.513	0.99
18_K	306_D	0.513	0.99
5_V	30_V	0.513	0.99
226_N	229_G	0.513	0.99
120_A	190_L	0.513	0.99
158_A	163_E	0.512	0.99
19_A	308_V	0.512	0.99
247_T	274_L	0.511	0.99
328_E	331_S	0.509	0.99
49_G	55_A	0.509	0.99
129_E	165_E	0.509	0.99
198_I	271_Y	0.508	0.99
297_Q	333_G	0.506	0.99
117_I	254_P	0.506	0.99
266_Y	289_C	0.506	0.99
40_E	370_K	0.506	0.99
313_A	320_D	0.506	0.99
225_P	230_M	0.504	0.99
99_A	289_C	0.503	0.99
366_H	372_A	0.503	0.99
298_P	301_L	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3mjfA	1	0.9837	100	0.295	Contact Map
3lp8A	1	0.965	100	0.299	Contact Map
2ip4A	1	0.9627	100	0.301	Contact Map
2yw2A	2	0.9837	100	0.307	Contact Map
2qk4A	1	0.972	100	0.308	Contact Map
2yrxA	1	0.9557	100	0.316	Contact Map
2xclA	1	0.9744	100	0.318	Contact Map
3n6rA	1	0.8019	100	0.346	Contact Map
4rcnA	6	0.8741	100	0.347	Contact Map
3u9tA	3	0.9277	100	0.348	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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