PEPD - ECOLI - GREMLIN Contacts

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PEPD - Cytosol non-specific dipeptidase

UniProt:	P15288	Sequences: MSELSQLSPQPLWDIFAKICSIPHPSYHEEQLAEYIVGWAKEKGFHVERDQVGNILIRKPATAGMENRKPVVLQAHLDMVPQKNNDTVHDFTKDPIQPYIDGEWVKARGTTLGADNGIGMASALAVLADENVVHGPLEVLLTMTEEAGMDGAFGLQGNWLQADILINTDSEEEGEIYMGCAGGIDFTSNLHLDREAVPAGFETFKLTLKGLKGGHSGGEIHVGLGNANKLLVRFLAGHAEELDLRLIDFNGGTLRNAIPREAFATIAVAADKVDVLKSLVNTYQEILKNELAEKEKNLALLLDSVANDKAALIAKSRDTFIRLLNATPNGVIRNSDVAKGVVETSLNVGVVTMTDNNVEIHCLIRSLIDSGKDYVVSMLDSLGKLAGAKTEAKGAYPGWQPDANSPVMHLVRETYQRLFNKTPNIQIIHAGLECGLFKKPYPEMDMVSIGPTITGPHSPDEQVHIESVGHYWTLLTELLKEIPAK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10695
Length:	485 (471)
Sequences:	1631 (1262)
Seq/√Len:	58.1

ECOLI - PEPD
BACSU - YQJN ROCB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
416_Q	422_T	5.676	1.00
97_Q	108_R	4.927	1.00
133_V	480_K	3.887	1.00
90_D	93_K	3.843	1.00
99_Y	108_R	3.632	1.00
72_V	162_A	3.614	1.00
103_E	466_E	3.592	1.00
43_K	128_A	3.528	1.00
38_G	42_E	3.319	1.00
19_I	32_L	3.299	1.00
103_E	464_H	3.289	1.00
477_E	480_K	3.219	1.00
123_A	139_V	3.215	1.00
61_A	136_P	2.997	1.00
20_C	24_H	2.941	1.00
225_G	291_L	2.795	1.00
51_Q	156_Q	2.767	1.00
453_I	456_P	2.715	1.00
72_V	444_M	2.711	1.00
40_A	47_V	2.642	1.00
36_I	77_L	2.624	1.00
122_S	471_Y	2.611	1.00
37_V	41_K	2.585	1.00
469_G	473_T	2.585	1.00
30_E	34_E	2.581	1.00
164_I	407_V	2.572	1.00
15_I	128_A	2.539	1.00
11_P	128_A	2.454	1.00
45_F	57_I	2.446	1.00
166_I	449_I	2.429	1.00
33_A	49_R	2.417	1.00
203_T	267_A	2.408	1.00
341_V	427_I	2.396	1.00
463_V	468_V	2.354	1.00
89_H	95_P	2.324	1.00
69_K	163_D	2.291	1.00
27_Y	144_T	2.291	1.00
231_L	262_A	2.273	1.00
205_K	303_D	2.229	1.00
144_T	150_D	2.222	1.00
411_V	478_L	2.216	1.00
28_H	92_T	2.212	1.00
37_V	47_V	2.212	1.00
37_V	55_I	2.210	1.00
100_I	465_I	2.101	1.00
233_R	290_E	2.100	1.00
313_I	316_S	2.099	1.00
231_L	264_A	2.035	1.00
58_R	161_Q	2.027	1.00
372_K	395_A	2.006	1.00
179_G	427_I	2.003	1.00
77_L	141_L	1.980	1.00
25_P	28_H	1.975	1.00
205_K	263_F	1.952	1.00
380_D	384_K	1.915	1.00
414_T	477_E	1.909	1.00
52_V	143_M	1.904	1.00
71_V	479_L	1.895	1.00
75_A	119_G	1.888	1.00
413_E	417_R	1.877	1.00
99_Y	106_K	1.861	1.00
18_K	21_S	1.856	1.00
34_E	38_G	1.846	1.00
208_L	300_L	1.842	1.00
15_I	43_K	1.837	1.00
46_H	58_R	1.823	0.99
233_R	370_S	1.822	0.99
227_A	262_A	1.813	0.99
104_W	462_Q	1.778	0.99
185_D	255_R	1.777	0.99
225_G	230_L	1.761	0.99
163_D	443_E	1.753	0.99
52_V	154_G	1.739	0.99
284_Q	288_K	1.729	0.99
312_L	358_V	1.723	0.99
20_C	98_P	1.684	0.99
37_V	49_R	1.683	0.99
411_V	447_V	1.681	0.99
201_F	267_A	1.662	0.99
84_N	261_E	1.651	0.99
70_P	162_A	1.637	0.99
353_M	358_V	1.633	0.99
132_V	476_T	1.630	0.99
84_N	87_T	1.625	0.99
343_E	371_G	1.624	0.99
82_Q	260_R	1.610	0.99
204_F	276_L	1.595	0.99
417_R	481_E	1.586	0.99
229_K	378_M	1.566	0.98
247_I	311_A	1.552	0.98
89_H	94_D	1.551	0.98
129_D	132_V	1.547	0.98
165_L	446_M	1.538	0.98
290_E	370_S	1.535	0.98
118_I	463_V	1.532	0.98
17_A	21_S	1.518	0.98
184_I	376_V	1.491	0.98
104_W	454_T	1.489	0.98
412_R	423_P	1.464	0.98
21_S	95_P	1.457	0.97
58_R	136_P	1.455	0.97
208_L	230_L	1.446	0.97
127_L	139_V	1.420	0.97
126_V	137_L	1.418	0.97
230_L	287_L	1.417	0.97
412_R	422_T	1.416	0.97
176_I	474_L	1.412	0.97
46_H	50_D	1.407	0.97
417_R	477_E	1.399	0.97
59_K	127_L	1.399	0.97
48_E	56_L	1.386	0.97
414_T	418_L	1.384	0.97
188_S	383_G	1.379	0.96
335_S	340_G	1.378	0.96
43_K	124_L	1.374	0.96
190_L	388_A	1.364	0.96
218_G	221_H	1.360	0.96
346_L	379_L	1.359	0.96
27_Y	150_D	1.356	0.96
28_H	31_Q	1.354	0.96
405_S	445_D	1.338	0.96
189_N	357_N	1.338	0.96
320_F	358_V	1.328	0.96
148_G	180_C	1.325	0.96
48_E	58_R	1.324	0.95
464_H	467_S	1.315	0.95
38_G	41_K	1.310	0.95
414_T	481_E	1.308	0.95
212_K	224_L	1.306	0.95
452_T	464_H	1.305	0.95
477_E	481_E	1.304	0.95
418_L	474_L	1.302	0.95
335_S	338_A	1.302	0.95
251_G	262_A	1.301	0.95
84_N	109_G	1.298	0.95
281_N	284_Q	1.294	0.95
24_H	32_L	1.290	0.95
48_E	159_W	1.288	0.95
86_D	109_G	1.284	0.95
260_R	459_P	1.271	0.94
27_Y	147_A	1.261	0.94
369_D	372_K	1.249	0.94
101_D	106_K	1.249	0.94
197_V	201_F	1.248	0.94
312_L	353_M	1.237	0.94
45_F	50_D	1.236	0.93
122_S	475_L	1.236	0.93
177_Y	426_Q	1.233	0.93
293_E	296_K	1.231	0.93
102_G	466_E	1.225	0.93
87_T	109_G	1.223	0.93
22_I	35_Y	1.222	0.93
203_T	308_D	1.210	0.93
204_F	302_L	1.205	0.93
467_S	470_H	1.204	0.93
173_E	470_H	1.203	0.93
91_F	94_D	1.202	0.92
293_E	337_V	1.202	0.92
402_D	445_D	1.202	0.92
226_N	259_P	1.200	0.92
34_E	49_R	1.189	0.92
211_L	230_L	1.188	0.92
473_T	476_T	1.188	0.92
95_P	98_P	1.179	0.92
376_V	392_A	1.177	0.92
14_D	18_K	1.170	0.91
191_H	316_S	1.161	0.91
129_D	472_W	1.156	0.91
35_Y	124_L	1.153	0.91
476_T	480_K	1.152	0.91
191_H	389_K	1.152	0.91
186_F	364_I	1.146	0.91
404_N	409_H	1.140	0.90
193_D	313_I	1.133	0.90
147_A	150_D	1.133	0.90
335_S	341_V	1.131	0.90
184_I	392_A	1.129	0.90
245_R	317_R	1.128	0.90
259_P	329_N	1.124	0.90
333_R	336_D	1.117	0.89
24_H	96_I	1.114	0.89
453_I	463_V	1.112	0.89
449_I	475_L	1.112	0.89
69_K	164_I	1.109	0.89
234_F	300_L	1.105	0.89
455_G	462_Q	1.103	0.89
30_E	53_G	1.102	0.89
272_K	275_V	1.099	0.89
274_D	277_K	1.096	0.89
202_E	304_S	1.087	0.88
234_F	283_Y	1.087	0.88
92_T	95_P	1.083	0.88
62_T	129_D	1.076	0.88
45_F	49_R	1.075	0.88
75_A	123_A	1.074	0.88
56_L	159_W	1.069	0.87
206_L	266_I	1.065	0.87
205_K	265_T	1.064	0.87
225_G	298_L	1.063	0.87
91_F	111_T	1.059	0.87
190_L	323_L	1.050	0.86
244_L	266_I	1.049	0.86
219_E	222_V	1.049	0.86
82_Q	111_T	1.045	0.86
73_L	123_A	1.043	0.86
322_R	384_K	1.042	0.86
204_F	304_S	1.042	0.86
30_E	49_R	1.038	0.86
374_Y	378_M	1.036	0.86
132_V	472_W	1.035	0.85
63_A	133_V	1.035	0.85
34_E	37_V	1.024	0.85
224_L	455_G	1.023	0.85
344_T	371_G	1.022	0.85
189_N	193_D	1.021	0.85
126_V	476_T	1.021	0.85
248_D	265_T	1.020	0.85
96_I	99_Y	1.018	0.85
40_A	43_K	1.005	0.84
255_R	363_L	1.005	0.84
11_P	14_D	1.001	0.84
84_N	460_D	1.000	0.83
274_D	278_S	0.999	0.83
273_V	277_K	0.998	0.83
149_M	363_L	0.997	0.83
116_N	456_P	0.995	0.83
201_F	269_A	0.992	0.83
60_P	136_P	0.990	0.83
410_L	478_L	0.989	0.83
411_V	474_L	0.986	0.83
402_D	438_K	0.983	0.82
39_W	124_L	0.983	0.82
455_G	460_D	0.982	0.82
311_A	317_R	0.981	0.82
129_D	133_V	0.979	0.82
332_I	375_V	0.979	0.82
289_N	400_Q	0.979	0.82
140_L	155_L	0.978	0.82
295_E	298_L	0.977	0.82
409_H	412_R	0.976	0.82
327_T	383_G	0.975	0.82
189_N	391_E	0.974	0.82
65_M	68_R	0.974	0.82
283_Y	287_L	0.973	0.82
183_G	396_Y	0.970	0.82
57_I	127_L	0.969	0.81
401_P	408_M	0.966	0.81
180_C	186_F	0.964	0.81
326_A	382_L	0.964	0.81
179_G	401_P	0.959	0.81
247_I	308_D	0.956	0.81
209_K	299_A	0.955	0.81
33_A	37_V	0.955	0.81
19_I	120_M	0.951	0.80
172_E	454_T	0.951	0.80
190_L	316_S	0.950	0.80
29_E	144_T	0.943	0.80
118_I	468_V	0.939	0.79
238_H	276_L	0.938	0.79
362_C	365_R	0.938	0.79
204_F	273_V	0.935	0.79
43_K	47_V	0.935	0.79
189_N	389_K	0.935	0.79
408_M	447_V	0.933	0.79
46_H	49_R	0.933	0.79
33_A	77_L	0.933	0.79
36_I	57_I	0.932	0.79
249_F	351_V	0.930	0.79
315_K	319_T	0.929	0.79
13_W	465_I	0.928	0.79
326_A	386_A	0.928	0.79
203_T	247_I	0.925	0.78
202_E	268_V	0.924	0.78
468_V	472_W	0.923	0.78
278_S	281_N	0.917	0.78
325_N	374_Y	0.913	0.77
323_L	383_G	0.912	0.77
85_N	263_F	0.911	0.77
196_A	200_G	0.908	0.77
277_K	281_N	0.906	0.77
178_M	403_A	0.904	0.77
287_L	290_E	0.903	0.77
351_V	360_I	0.897	0.76
175_E	426_Q	0.894	0.76
176_I	449_I	0.893	0.76
198_P	201_F	0.890	0.76
162_A	167_N	0.890	0.76
436_L	439_K	0.890	0.76
212_K	297_N	0.889	0.76
275_V	279_L	0.888	0.75
106_K	462_Q	0.888	0.75
166_I	475_L	0.887	0.75
95_P	101_D	0.885	0.75
82_Q	253_T	0.885	0.75
197_V	200_G	0.882	0.75
338_A	341_V	0.881	0.75
342_V	430_A	0.879	0.75
196_A	201_F	0.876	0.74
273_V	304_S	0.871	0.74
61_A	68_R	0.871	0.74
232_V	325_N	0.870	0.74
254_L	458_S	0.866	0.74
320_F	360_I	0.865	0.74
354_T	357_N	0.863	0.73
413_E	481_E	0.860	0.73
175_E	424_N	0.856	0.73
257_A	260_R	0.856	0.73
243_D	314_A	0.855	0.73
180_C	436_L	0.854	0.73
170_S	175_E	0.853	0.72
291_L	298_L	0.849	0.72
162_A	165_L	0.848	0.72
197_V	267_A	0.846	0.72
176_I	423_P	0.845	0.72
406_P	410_L	0.843	0.72
170_S	456_P	0.842	0.72
58_R	138_E	0.840	0.71
402_D	408_M	0.839	0.71
15_I	35_Y	0.839	0.71
144_T	147_A	0.838	0.71
269_A	272_K	0.836	0.71
209_K	301_L	0.834	0.71
191_H	357_N	0.833	0.71
281_N	285_E	0.832	0.71
454_T	462_Q	0.832	0.71
242_L	276_L	0.832	0.71
158_N	441_Y	0.832	0.71
377_S	380_D	0.827	0.70
408_M	445_D	0.825	0.70
104_W	455_G	0.825	0.70
25_P	92_T	0.824	0.70
419_F	470_H	0.824	0.70
335_S	427_I	0.823	0.70
178_M	182_G	0.822	0.70
341_V	367_L	0.817	0.69
197_V	311_A	0.815	0.69
17_A	20_C	0.813	0.69
89_H	96_I	0.812	0.69
283_Y	286_I	0.808	0.68
452_T	467_S	0.808	0.68
206_L	302_L	0.805	0.68
266_I	276_L	0.804	0.68
106_K	460_D	0.804	0.68
333_R	371_G	0.803	0.68
17_A	105_V	0.802	0.68
92_T	96_I	0.798	0.67
402_D	409_H	0.798	0.67
120_M	141_L	0.794	0.67
282_T	285_E	0.793	0.67
82_Q	254_L	0.792	0.67
87_T	261_E	0.790	0.67
61_A	133_V	0.790	0.67
85_N	261_E	0.789	0.67
396_Y	399_W	0.783	0.66
333_R	344_T	0.782	0.66
410_L	414_T	0.776	0.65
365_R	368_I	0.776	0.65
39_W	43_K	0.775	0.65
87_T	97_Q	0.772	0.65
209_K	261_E	0.772	0.65
75_A	120_M	0.772	0.65
116_N	172_E	0.771	0.65
30_E	33_A	0.770	0.65
94_D	97_Q	0.770	0.65
89_H	92_T	0.769	0.65
364_I	375_V	0.769	0.65
209_K	263_F	0.768	0.64
162_A	169_D	0.765	0.64
245_R	314_A	0.764	0.64
349_G	363_L	0.764	0.64
170_S	448_S	0.764	0.64
40_A	44_G	0.762	0.64
173_E	467_S	0.758	0.63
466_E	470_H	0.755	0.63
233_R	385_L	0.754	0.63
89_H	111_T	0.752	0.63
364_I	379_L	0.751	0.63
346_L	362_C	0.750	0.63
284_Q	299_A	0.749	0.62
322_R	385_L	0.747	0.62
354_T	359_E	0.745	0.62
202_E	270_A	0.745	0.62
312_L	316_S	0.744	0.62
102_G	464_H	0.743	0.62
179_G	186_F	0.736	0.61
268_V	276_L	0.736	0.61
381_S	385_L	0.736	0.61
176_I	411_V	0.735	0.61
126_V	479_L	0.734	0.61
373_D	376_V	0.731	0.61
20_C	32_L	0.731	0.61
282_T	286_I	0.730	0.60
164_I	445_D	0.729	0.60
267_A	307_N	0.727	0.60
208_L	211_L	0.726	0.60
182_G	186_F	0.725	0.60
203_T	307_N	0.725	0.60
9_P	12_L	0.724	0.60
172_E	175_E	0.721	0.60
32_L	77_L	0.721	0.60
10_Q	14_D	0.721	0.60
233_R	236_A	0.721	0.60
314_A	318_D	0.721	0.60
156_Q	440_P	0.720	0.59
277_K	304_S	0.719	0.59
180_C	183_G	0.717	0.59
196_A	310_A	0.714	0.59
140_L	158_N	0.712	0.59
28_H	81_P	0.712	0.59
76_H	115_D	0.710	0.58
9_P	13_W	0.710	0.58
31_Q	93_K	0.709	0.58
208_L	231_L	0.709	0.58
337_V	403_A	0.708	0.58
69_K	406_P	0.708	0.58
102_G	106_K	0.704	0.58
170_S	173_E	0.703	0.58
418_L	477_E	0.703	0.58
106_K	458_S	0.703	0.58
223_G	336_D	0.702	0.57
268_V	273_V	0.701	0.57
177_Y	180_C	0.701	0.57
207_T	263_F	0.700	0.57
200_G	249_F	0.699	0.57
232_V	249_F	0.696	0.57
305_V	308_D	0.695	0.57
111_T	459_P	0.694	0.57
359_E	365_R	0.694	0.57
156_Q	159_W	0.693	0.56
116_N	218_G	0.693	0.56
196_A	404_N	0.692	0.56
87_T	108_R	0.691	0.56
33_A	55_I	0.691	0.56
36_I	124_L	0.691	0.56
176_I	478_L	0.691	0.56
437_F	444_M	0.690	0.56
83_K	86_D	0.686	0.56
70_P	136_P	0.685	0.56
77_L	143_M	0.684	0.56
218_G	456_P	0.684	0.56
20_C	96_I	0.684	0.56
186_F	392_A	0.683	0.55
123_A	168_T	0.683	0.55
100_I	105_V	0.682	0.55
62_T	131_N	0.681	0.55
84_N	260_R	0.681	0.55
18_K	35_Y	0.680	0.55
40_A	57_I	0.680	0.55
470_H	474_L	0.680	0.55
236_A	325_N	0.679	0.55
441_Y	444_M	0.679	0.55
244_L	321_I	0.676	0.55
378_M	382_L	0.675	0.55
122_S	126_V	0.672	0.54
170_S	177_Y	0.670	0.54
49_R	55_I	0.669	0.54
179_G	185_D	0.668	0.54
403_A	406_P	0.667	0.54
402_D	405_S	0.666	0.54
326_A	385_L	0.666	0.54
277_K	302_L	0.665	0.53
382_L	386_A	0.665	0.53
47_V	50_D	0.664	0.53
140_L	157_G	0.662	0.53
319_T	323_L	0.659	0.53
86_D	360_I	0.659	0.53
348_V	360_I	0.659	0.53
250_N	352_T	0.658	0.53
126_V	475_L	0.657	0.53
383_G	388_A	0.656	0.52
359_E	362_C	0.655	0.52
212_K	295_E	0.654	0.52
133_V	476_T	0.653	0.52
326_A	330_G	0.652	0.52
168_T	171_E	0.652	0.52
162_A	171_E	0.650	0.52
266_I	302_L	0.649	0.52
13_W	468_V	0.647	0.51
278_S	282_T	0.647	0.51
204_F	277_K	0.646	0.51
457_H	461_E	0.646	0.51
25_P	81_P	0.646	0.51
89_H	98_P	0.645	0.51
184_I	364_I	0.644	0.51
236_A	381_S	0.644	0.51
183_G	186_F	0.641	0.51
359_E	367_L	0.640	0.51
322_R	326_A	0.639	0.51
74_Q	142_T	0.638	0.50
63_A	318_D	0.638	0.50
45_F	127_L	0.637	0.50
464_H	468_V	0.637	0.50
33_A	53_G	0.635	0.50
438_K	446_M	0.635	0.50
45_F	59_K	0.633	0.50
179_G	182_G	0.632	0.50
223_G	294_K	0.631	0.50
169_D	172_E	0.631	0.50
212_K	225_G	0.630	0.50
410_L	413_E	0.630	0.50
82_Q	459_P	0.629	0.49
337_V	400_Q	0.629	0.49
476_T	479_L	0.628	0.49
62_T	133_V	0.627	0.49
287_L	300_L	0.626	0.49
126_V	133_V	0.626	0.49
108_R	447_V	0.626	0.49
105_V	206_L	0.624	0.49
96_I	101_D	0.624	0.49
323_L	386_A	0.622	0.49
257_A	459_P	0.622	0.49
278_S	304_S	0.621	0.49
10_Q	469_G	0.621	0.49
12_L	122_S	0.618	0.48
186_F	197_V	0.617	0.48
236_A	321_I	0.616	0.48
223_G	255_R	0.615	0.48
178_M	401_P	0.615	0.48
418_L	473_T	0.613	0.48
297_N	301_L	0.612	0.48
13_W	401_P	0.612	0.48
104_W	452_T	0.611	0.47
320_F	324_L	0.609	0.47
365_R	369_D	0.609	0.47
265_T	305_V	0.609	0.47
419_F	474_L	0.609	0.47
105_V	465_I	0.606	0.47
177_Y	432_L	0.605	0.47
54_N	142_T	0.605	0.47
438_K	443_E	0.605	0.47
15_I	124_L	0.604	0.47
190_L	312_L	0.604	0.47
166_I	478_L	0.604	0.47
327_T	362_C	0.604	0.47
250_N	263_F	0.603	0.47
140_L	437_F	0.603	0.47
111_T	260_R	0.602	0.46
167_N	171_E	0.601	0.46
363_L	369_D	0.600	0.46
100_I	106_K	0.600	0.46
54_N	74_Q	0.599	0.46
39_W	45_F	0.598	0.46
239_A	318_D	0.597	0.46
189_N	359_E	0.597	0.46
429_H	433_E	0.597	0.46
12_L	125_A	0.596	0.46
324_L	437_F	0.596	0.46
76_H	80_V	0.596	0.46
419_F	473_T	0.595	0.46
144_T	148_G	0.595	0.46
77_L	120_M	0.593	0.45
247_I	265_T	0.592	0.45
247_I	267_A	0.592	0.45
164_I	169_D	0.591	0.45
249_F	353_M	0.591	0.45
126_V	472_W	0.590	0.45
12_L	468_V	0.590	0.45
245_R	311_A	0.590	0.45
203_T	265_T	0.589	0.45
414_T	478_L	0.589	0.45
326_A	381_S	0.588	0.45
447_V	470_H	0.588	0.45
89_H	97_Q	0.585	0.45
192_L	353_M	0.585	0.45
190_L	319_T	0.585	0.45
380_D	392_A	0.584	0.45
412_R	425_I	0.583	0.44
39_W	55_I	0.582	0.44
164_I	167_N	0.581	0.44
364_I	367_L	0.581	0.44
172_E	218_G	0.580	0.44
115_D	457_H	0.579	0.44
317_R	321_I	0.579	0.44
228_N	231_L	0.579	0.44
180_C	185_D	0.578	0.44
276_L	279_L	0.578	0.44
205_K	305_V	0.577	0.44
249_F	320_F	0.577	0.44
84_N	257_A	0.576	0.44
18_K	39_W	0.576	0.44
82_Q	91_F	0.576	0.44
363_L	367_L	0.574	0.43
59_K	134_H	0.573	0.43
78_D	145_E	0.573	0.43
41_K	47_V	0.573	0.43
14_D	21_S	0.572	0.43
369_D	398_G	0.572	0.43
20_C	349_G	0.571	0.43
106_K	109_G	0.571	0.43
218_G	437_F	0.571	0.43
373_D	395_A	0.570	0.43
156_Q	441_Y	0.570	0.43
167_N	217_G	0.569	0.43
238_H	244_L	0.569	0.43
367_L	427_I	0.567	0.43
356_N	365_R	0.567	0.43
163_D	441_Y	0.566	0.43
292_A	404_N	0.565	0.42
168_T	172_E	0.565	0.42
237_G	283_Y	0.564	0.42
279_L	282_T	0.564	0.42
188_S	388_A	0.564	0.42
239_A	244_L	0.563	0.42
59_K	139_V	0.563	0.42
250_N	278_S	0.562	0.42
275_V	278_S	0.562	0.42
12_L	471_Y	0.562	0.42
193_D	316_S	0.561	0.42
431_G	434_C	0.561	0.42
356_N	359_E	0.560	0.42
100_I	103_E	0.559	0.42
415_Y	421_K	0.558	0.42
51_Q	263_F	0.558	0.42
157_G	441_Y	0.558	0.42
15_I	18_K	0.557	0.42
160_L	168_T	0.556	0.41
192_L	358_V	0.556	0.41
92_T	98_P	0.556	0.41
352_T	359_E	0.556	0.41
86_D	92_T	0.556	0.41
226_N	329_N	0.555	0.41
313_I	317_R	0.554	0.41
179_G	183_G	0.554	0.41
47_V	58_R	0.553	0.41
228_N	246_L	0.553	0.41
126_V	132_V	0.553	0.41
207_T	303_D	0.553	0.41
137_L	266_I	0.553	0.41
250_N	353_M	0.552	0.41
106_K	455_G	0.552	0.41
192_L	356_N	0.551	0.41
418_L	470_H	0.551	0.41
416_Q	423_P	0.551	0.41
408_M	437_F	0.549	0.41
218_G	222_V	0.549	0.41
39_W	42_E	0.548	0.41
54_N	429_H	0.547	0.41
180_C	435_G	0.547	0.41
230_L	291_L	0.544	0.40
43_K	130_E	0.543	0.40
414_T	474_L	0.542	0.40
319_T	386_A	0.540	0.40
70_P	161_Q	0.539	0.40
367_L	371_G	0.539	0.40
164_I	171_E	0.539	0.40
474_L	478_L	0.538	0.40
418_L	439_K	0.537	0.39
223_G	334_N	0.537	0.39
338_A	427_I	0.537	0.39
98_P	101_D	0.536	0.39
287_L	298_L	0.534	0.39
98_P	254_L	0.534	0.39
206_L	285_E	0.534	0.39
9_P	469_G	0.533	0.39
23_P	79_M	0.533	0.39
53_G	143_M	0.532	0.39
24_H	75_A	0.531	0.39
122_S	177_Y	0.531	0.39
192_L	196_A	0.530	0.39
58_R	70_P	0.530	0.39
169_D	173_E	0.530	0.39
243_D	272_K	0.528	0.38
18_K	42_E	0.528	0.38
218_G	453_I	0.528	0.38
11_P	130_E	0.527	0.38
33_A	143_M	0.527	0.38
171_E	174_G	0.527	0.38
184_I	255_R	0.526	0.38
237_G	286_I	0.526	0.38
241_E	275_V	0.526	0.38
193_D	197_V	0.526	0.38
26_S	29_E	0.525	0.38
334_N	342_V	0.525	0.38
344_T	366_S	0.524	0.38
401_P	405_S	0.524	0.38
236_A	322_R	0.523	0.38
65_M	133_V	0.523	0.38
171_E	256_N	0.520	0.38
165_L	169_D	0.520	0.38
83_K	91_F	0.519	0.38
231_L	266_I	0.517	0.37
207_T	301_L	0.517	0.37
74_Q	167_N	0.515	0.37
203_T	305_V	0.515	0.37
454_T	458_S	0.514	0.37
253_T	350_V	0.514	0.37
200_G	269_A	0.514	0.37
116_N	219_E	0.513	0.37
334_N	340_G	0.511	0.37
188_S	323_L	0.510	0.37
409_H	413_E	0.510	0.37
115_D	461_E	0.510	0.37
39_W	57_I	0.510	0.37
43_K	57_I	0.510	0.37
87_T	91_F	0.509	0.37
379_L	392_A	0.508	0.36
237_G	289_N	0.507	0.36
24_H	346_L	0.506	0.36
332_I	346_L	0.506	0.36
284_Q	298_L	0.506	0.36
256_N	431_G	0.505	0.36
326_A	335_S	0.504	0.36
202_E	273_V	0.502	0.36
293_E	336_D	0.502	0.36
153_F	440_P	0.500	0.36
191_H	276_L	0.500	0.36

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2qyvA	2	0.967	100	0.399	Contact Map
3mruA	1	1	100	0.414	Contact Map
3rzaA	2	0.7299	100	0.613	Contact Map
3pfoA	2	0.7567	100	0.613	Contact Map
3ifeA	2	0.7443	100	0.62	Contact Map
3gb0A	2	0.7299	100	0.621	Contact Map
3khxA	1	0.8	100	0.627	Contact Map
4g1pA	2	0.7546	100	0.63	Contact Map
2pokA	2	0.868	100	0.632	Contact Map
3pfeA	2	0.7505	100	0.632	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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