PUR4 - ECOLI - GREMLIN Contacts

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PUR4 - Phosphoribosylformylglycinamidine synthase

UniProt:	P15254	Sequences: MMEILRGSPALSAFRINKLLARFQAARLPVHNIYAEYVHFADLNAPLNDDEHAQLERLLKYGPALASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVNRLERGVAYYIEAGTLTNEQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTSVDLLGQGRQALIDANLRLGLALAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWVIDGEQQPKSLFKMIKNTFETTPDHVLSAYKDNAAVMEGSEVGRYFADHETGRYDFHQEPAHILMKVETHNHPTAISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIVTALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNIRADHVQKGEINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERRCQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELREILSDEPGMSPLEIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGEATEELHLSLHDRHFDNQPIDLPLDVLLGKTPKMTRDVQTLKAKGDALAREGITIADAVKRVLHLPTVAEKTFLVTIGDRSVTGMVARDQMVGPWQVPVANCAVTTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEALTNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMSMKTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLSTEDNALLLIDLGKGNNALGATALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAEMAFAGHCGIDADIATLGDDRLAALFNEELGAVIQVRAADREAVESVLAQHGLADCVHYVGQAVSGDRFVITANGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVKLSFDINEDVAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLTGRTGLEDFHALVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQMMSNLRELIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGRVEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRVTIMMPHPERVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10797
Length:	1295 (1209)
Sequences:	1748 (986)
Seq/√Len:	28.3

ECOLI - PUR4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
162_D	200_N	5.330	1.00
512_M	577_I	5.179	1.00
437_V	555_V	5.140	1.00
240_M	244_T	5.135	1.00
618_T	755_E	5.076	1.00
712_A	756_A	4.417	1.00
227_V	613_T	4.301	1.00
1087_A	1130_L	4.277	1.00
526_E	529_E	4.173	1.00
894_L	907_A	4.150	1.00
1075_L	1116_V	4.148	1.00
39_H	61_Y	3.977	1.00
596_Q	599_D	3.948	1.00
893_T	928_V	3.796	1.00
819_L	826_L	3.744	1.00
719_A	802_I	3.712	1.00
994_R	1003_D	3.605	1.00
903_C	958_A	3.587	1.00
167_G	170_A	3.580	1.00
163_L	166_Q	3.565	1.00
1003_D	1007_Q	3.557	1.00
1161_T	1200_R	3.510	1.00
241_I	244_T	3.426	1.00
703_V	714_L	3.399	1.00
564_D	568_K	3.369	1.00
680_C	726_T	3.355	1.00
120_T	123_Q	3.353	1.00
413_L	801_V	3.321	1.00
401_G	408_H	3.312	1.00
684_T	811_V	3.261	1.00
717_G	925_L	3.238	1.00
894_L	905_I	3.233	1.00
815_I	874_V	3.221	1.00
829_I	929_I	3.207	1.00
720_L	734_I	3.203	1.00
173_D	177_R	3.139	1.00
637_V	891_L	3.089	1.00
723_I	734_I	3.040	1.00
640_V	646_V	2.991	1.00
723_I	728_I	2.977	1.00
983_V	1010_S	2.932	1.00
1131_A	1254_V	2.914	1.00
413_L	697_I	2.913	1.00
1081_G	1119_E	2.893	1.00
1176_Q	1186_V	2.886	1.00
1206_A	1210_A	2.875	1.00
833_K	862_Q	2.862	1.00
963_R	975_S	2.855	1.00
731_I	734_I	2.845	1.00
1218_V	1244_I	2.794	1.00
1220_L	1246_A	2.793	1.00
906_D	957_Q	2.788	1.00
890_L	928_V	2.748	1.00
390_R	649_K	2.744	1.00
1213_E	1218_V	2.698	1.00
168_R	188_D	2.642	1.00
895_A	964_F	2.632	0.99
584_L	603_D	2.631	0.99
661_T	664_V	2.613	0.99
660_V	1052_S	2.613	0.99
237_L	241_I	2.598	0.99
879_L	929_I	2.591	0.99
233_Q	240_M	2.587	0.99
642_H	987_E	2.581	0.99
1041_K	1084_D	2.572	0.99
560_L	576_V	2.571	0.99
517_S	606_L	2.537	0.99
638_K	984_W	2.498	0.99
20_L	24_Q	2.479	0.99
164_L	200_N	2.450	0.99
1041_K	1066_D	2.446	0.99
367_T	992_M	2.424	0.99
735_K	771_T	2.417	0.99
561_P	564_D	2.415	0.99
233_Q	758_K	2.411	0.99
870_I	879_L	2.409	0.99
824_N	880_L	2.383	0.99
943_L	952_V	2.373	0.99
1104_E	1143_N	2.371	0.99
1083_E	1122_T	2.366	0.99
906_D	965_V	2.365	0.99
1122_T	1126_R	2.342	0.99
555_V	560_L	2.328	0.99
236_S	240_M	2.310	0.99
1173_E	1189_Q	2.305	0.99
827_L	954_Y	2.289	0.99
1174_V	1220_L	2.273	0.98
1121_A	1125_H	2.273	0.98
637_V	895_A	2.268	0.98
750_D	795_T	2.263	0.98
730_D	733_R	2.253	0.98
39_H	62_G	2.241	0.98
233_Q	244_T	2.232	0.98
990_W	1003_D	2.228	0.98
168_R	172_I	2.224	0.98
704_A	715_A	2.206	0.98
827_L	940_E	2.206	0.98
719_A	804_A	2.199	0.98
165_G	200_N	2.193	0.98
1210_A	1214_S	2.191	0.98
169_Q	172_I	2.190	0.98
78_T	140_F	2.182	0.98
1224_D	1228_K	2.182	0.98
706_L	854_P	2.179	0.98
562_L	565_E	2.178	0.98
661_T	1195_S	2.175	0.98
663_M	684_T	2.175	0.98
638_K	980_T	2.170	0.98
30_V	114_I	2.162	0.98
305_W	473_D	2.146	0.98
279_R	1066_D	2.125	0.98
236_S	244_T	2.123	0.98
709_A	756_A	2.118	0.98
634_A	980_T	2.117	0.98
991_Q	994_R	2.107	0.97
95_A	106_L	2.104	0.97
435_K	555_V	2.093	0.97
708_F	752_G	2.089	0.97
240_M	245_F	2.076	0.97
987_E	991_Q	2.076	0.97
869_A	943_L	2.068	0.97
237_L	240_M	2.061	0.97
241_I	245_F	2.045	0.97
564_D	574_Y	2.035	0.97
679_N	886_S	2.032	0.97
559_Q	562_L	2.029	0.97
682_V	814_T	2.028	0.97
680_C	696_A	2.028	0.97
526_E	591_R	2.027	0.97
870_I	929_I	2.027	0.97
686_S	689_S	2.022	0.97
253_L	425_V	2.021	0.97
239_K	246_E	2.015	0.97
1056_M	1089_V	2.013	0.97
432_V	582_E	2.010	0.97
642_H	984_W	2.008	0.97
588_L	598_I	1.996	0.96
267_E	286_P	1.975	0.96
690_Y	812_R	1.974	0.96
585_H	599_D	1.969	0.96
1007_Q	1010_S	1.963	0.96
163_L	200_N	1.960	0.96
818_Q	901_G	1.958	0.96
872_A	876_Q	1.958	0.96
23_F	30_V	1.953	0.96
238_F	241_I	1.948	0.96
435_K	579_E	1.943	0.96
237_L	244_T	1.938	0.96
1004_Q	1161_T	1.936	0.96
183_A	612_M	1.928	0.96
869_A	942_V	1.928	0.96
73_K	124_W	1.927	0.96
42_D	104_N	1.926	0.96
902_H	982_R	1.925	0.96
1008_A	1235_A	1.915	0.95
1231_E	1243_G	1.910	0.95
229_D	244_T	1.907	0.95
824_N	881_A	1.906	0.95
1213_E	1242_N	1.902	0.95
286_P	422_A	1.900	0.95
174_A	178_L	1.887	0.95
156_T	541_E	1.886	0.95
413_L	737_S	1.879	0.95
1181_L	1286_I	1.878	0.95
723_I	804_A	1.876	0.95
1184_G	1285_R	1.874	0.95
1166_E	1194_V	1.871	0.95
740_W	743_A	1.862	0.95
740_W	744_A	1.860	0.95
648_E	986_A	1.859	0.95
15_R	110_V	1.856	0.95
701_A	801_V	1.854	0.95
825_A	933_A	1.854	0.95
229_D	240_M	1.853	0.95
827_L	931_V	1.845	0.94
894_L	928_V	1.841	0.94
137_E	473_D	1.840	0.94
229_D	233_Q	1.837	0.94
813_H	875_A	1.833	0.94
825_A	954_Y	1.832	0.94
928_V	955_V	1.831	0.94
442_P	573_P	1.830	0.94
673_W	902_H	1.823	0.94
1165_F	1195_S	1.819	0.94
288_H	422_A	1.815	0.94
1011_N	1226_F	1.812	0.94
1015_P	1225_N	1.803	0.94
1039_R	1066_D	1.788	0.93
625_A	852_D	1.782	0.93
1114_D	1118_D	1.781	0.93
128_T	140_F	1.779	0.93
827_L	952_V	1.772	0.93
1083_E	1119_E	1.771	0.93
1225_N	1235_A	1.766	0.93
895_A	899_F	1.765	0.93
1169_F	1191_P	1.764	0.93
707_D	854_P	1.748	0.93
524_K	579_E	1.746	0.93
602_L	606_L	1.744	0.93
820_S	1275_E	1.743	0.93
364_D	368_E	1.738	0.92
394_E	705_L	1.732	0.92
823_D	933_A	1.725	0.92
737_S	801_V	1.724	0.92
763_E	767_A	1.723	0.92
898_A	905_I	1.720	0.92
742_A	753_L	1.718	0.92
272_F	290_L	1.717	0.92
1072_M	1110_I	1.712	0.92
517_S	584_L	1.707	0.92
1042_V	1065_F	1.702	0.92
72_G	115_E	1.694	0.91
526_E	589_H	1.689	0.91
1249_T	1254_V	1.687	0.91
197_L	601_P	1.687	0.91
666_R	816_T	1.685	0.91
898_A	964_F	1.681	0.91
225_D	613_T	1.680	0.91
1201_V	1247_V	1.678	0.91
89_S	93_D	1.675	0.91
696_A	803_S	1.665	0.91
727_Q	809_E	1.665	0.91
828_L	885_R	1.663	0.91
576_V	579_E	1.660	0.91
682_V	694_A	1.654	0.90
180_L	206_L	1.654	0.90
650_T	989_T	1.651	0.90
869_A	946_H	1.651	0.90
73_K	121_N	1.642	0.90
371_L	655_I	1.641	0.90
81_P	138_T	1.637	0.90
741_M	744_A	1.629	0.90
685_A	691_Y	1.625	0.90
7_G	34_Y	1.624	0.90
983_V	1007_Q	1.622	0.90
659_S	1193_A	1.622	0.90
1104_E	1108_K	1.620	0.89
866_F	927_A	1.616	0.89
906_D	959_V	1.614	0.89
745_G	750_D	1.613	0.89
709_A	712_A	1.609	0.89
243_N	761_G	1.603	0.89
366_M	993_Q	1.601	0.89
528_R	590_D	1.601	0.89
680_C	814_T	1.601	0.89
1184_G	1282_P	1.596	0.89
1068_I	1081_G	1.590	0.89
600_L	606_L	1.586	0.88
827_L	929_I	1.586	0.88
289_I	693_E	1.585	0.88
277_T	286_P	1.581	0.88
367_T	371_L	1.580	0.88
162_D	165_G	1.577	0.88
1171_L	1189_Q	1.577	0.88
826_L	905_I	1.570	0.88
288_H	425_V	1.564	0.88
285_E	421_R	1.564	0.88
430_I	434_A	1.564	0.88
813_H	877_R	1.564	0.88
713_R	856_D	1.563	0.88
326_A	417_I	1.559	0.88
1131_A	1141_M	1.554	0.87
236_S	239_K	1.553	0.87
41_A	106_L	1.550	0.87
761_G	766_P	1.545	0.87
329_K	683_T	1.541	0.87
732_K	868_D	1.540	0.87
436_L	512_M	1.534	0.87
40_F	76_L	1.533	0.87
880_L	932_R	1.531	0.87
873_L	939_V	1.527	0.86
990_W	994_R	1.517	0.86
1028_D	1288_R	1.516	0.86
245_F	252_V	1.509	0.86
1159_R	1164_R	1.509	0.86
1004_Q	1230_T	1.508	0.86
235_K	762_E	1.507	0.86
885_R	928_V	1.506	0.86
438_V	512_M	1.506	0.86
76_L	111_A	1.499	0.85
965_V	975_S	1.495	0.85
829_I	870_I	1.493	0.85
1169_F	1270_N	1.491	0.85
1043_A	1070_V	1.490	0.85
119_L	124_W	1.487	0.85
635_D	639_R	1.485	0.85
401_G	407_Y	1.480	0.85
1088_L	1131_A	1.477	0.85
238_F	244_T	1.476	0.84
435_K	557_A	1.475	0.84
15_R	1163_D	1.474	0.84
225_D	611_K	1.474	0.84
445_N	541_E	1.473	0.84
190_L	209_F	1.472	0.84
226_W	614_R	1.471	0.84
162_D	166_Q	1.469	0.84
267_E	284_Q	1.468	0.84
676_P	817_P	1.463	0.84
1265_F	1269_S	1.463	0.84
942_V	946_H	1.455	0.84
1247_V	1256_I	1.454	0.84
342_I	388_Y	1.452	0.83
1189_Q	1227_G	1.448	0.83
524_K	589_H	1.446	0.83
401_G	406_G	1.445	0.83
192_D	196_K	1.440	0.83
632_T	635_D	1.439	0.83
160_S	202_N	1.439	0.83
990_W	995_L	1.437	0.83
1134_V	1220_L	1.436	0.83
1058_A	1265_F	1.433	0.83
522_G	584_L	1.428	0.82
767_A	860_V	1.422	0.82
1034_I	1037_G	1.421	0.82
435_K	560_L	1.419	0.82
51_E	102_Q	1.415	0.82
1190_M	1193_A	1.414	0.82
1015_P	1226_F	1.412	0.82
1052_S	1195_S	1.410	0.82
1175_T	1221_R	1.410	0.82
707_D	710_A	1.407	0.81
233_Q	241_I	1.400	0.81
528_R	591_R	1.399	0.81
878_K	942_V	1.398	0.81
487_R	566_L	1.395	0.81
821_T	824_N	1.394	0.81
976_E	981_L	1.393	0.81
819_L	905_I	1.389	0.81
648_E	989_T	1.388	0.81
720_L	770_L	1.387	0.81
172_I	176_L	1.387	0.81
345_F	366_M	1.384	0.80
696_A	726_T	1.383	0.80
566_L	569_R	1.381	0.80
12_S	1163_D	1.381	0.80
764_L	857_V	1.381	0.80
811_V	1267_T	1.378	0.80
524_K	583_E	1.374	0.80
1190_M	1278_G	1.370	0.80
1158_V	1202_E	1.366	0.79
699_E	704_A	1.359	0.79
1230_T	1235_A	1.358	0.79
1110_I	1120_F	1.358	0.79
982_R	1009_K	1.357	0.79
243_N	766_P	1.354	0.79
257_K	426_Q	1.354	0.79
895_A	905_I	1.352	0.79
1050_V	1091_C	1.351	0.79
349_W	988_T	1.351	0.79
157_P	591_R	1.351	0.79
512_M	516_V	1.350	0.79
1060_F	1089_V	1.349	0.79
1205_D	1208_H	1.345	0.78
242_K	245_F	1.343	0.78
744_A	750_D	1.341	0.78
760_V	802_I	1.340	0.78
157_P	595_N	1.338	0.78
692_G	811_V	1.337	0.78
386_N	696_A	1.337	0.78
1172_V	1245_T	1.335	0.78
905_I	956_G	1.335	0.78
587_S	599_D	1.330	0.78
487_R	569_R	1.327	0.77
290_L	325_G	1.325	0.77
525_F	577_I	1.325	0.77
530_I	577_I	1.321	0.77
679_N	883_H	1.318	0.77
272_F	421_R	1.317	0.77
324_R	428_G	1.317	0.77
1086_H	1130_L	1.317	0.77
824_N	958_A	1.313	0.77
371_L	1164_R	1.312	0.77
623_G	706_L	1.306	0.76
891_L	895_A	1.303	0.76
327_K	486_D	1.300	0.76
616_V	755_E	1.299	0.76
688_D	1058_A	1.296	0.76
275_H	289_I	1.294	0.76
443_A	532_S	1.292	0.75
254_S	438_V	1.291	0.75
1022_S	1188_S	1.288	0.75
231_E	244_T	1.288	0.75
233_Q	236_S	1.283	0.75
719_A	738_A	1.280	0.75
1212_L	1247_V	1.279	0.75
1168_R	1234_P	1.274	0.74
740_W	745_G	1.272	0.74
398_S	401_G	1.267	0.74
929_I	939_V	1.263	0.74
268_V	287_A	1.259	0.74
236_S	241_I	1.254	0.73
1267_T	1273_H	1.254	0.73
1223_V	1229_V	1.254	0.73
1270_N	1281_G	1.254	0.73
898_A	978_R	1.253	0.73
6_R	36_E	1.251	0.73
132_H	140_F	1.250	0.73
434_A	498_L	1.247	0.73
1244_I	1247_V	1.245	0.73
269_G	688_D	1.242	0.73
235_K	240_M	1.239	0.72
77_V	112_Y	1.237	0.72
160_S	595_N	1.237	0.72
905_I	955_V	1.236	0.72
678_A	817_P	1.235	0.72
865_G	946_H	1.233	0.72
531_L	575_A	1.233	0.72
680_C	725_A	1.232	0.72
192_D	195_T	1.230	0.72
52_H	55_L	1.229	0.72
1189_Q	1223_V	1.227	0.72
682_V	726_T	1.225	0.71
587_S	596_Q	1.224	0.71
266_S	429_E	1.222	0.71
742_A	750_D	1.216	0.71
75_L	114_I	1.215	0.71
603_D	606_L	1.213	0.71
634_A	638_K	1.212	0.71
524_K	587_S	1.211	0.71
487_R	1053_H	1.208	0.70
168_R	191_Q	1.206	0.70
1113_N	1116_V	1.204	0.70
266_S	499_F	1.203	0.70
633_I	637_V	1.203	0.70
23_F	33_I	1.203	0.70
1284_M	1288_R	1.201	0.70
12_S	15_R	1.201	0.70
902_H	962_D	1.198	0.70
740_W	750_D	1.196	0.70
870_I	943_L	1.195	0.70
717_G	863_L	1.195	0.70
229_D	232_Q	1.193	0.69
874_V	879_L	1.191	0.69
320_G	551_Y	1.191	0.69
1151_S	1154_W	1.190	0.69
243_N	247_T	1.189	0.69
532_S	537_M	1.188	0.69
1174_V	1246_A	1.188	0.69
905_I	964_F	1.187	0.69
878_K	938_A	1.187	0.69
660_V	1195_S	1.180	0.69
738_A	802_I	1.178	0.68
40_F	109_G	1.172	0.68
1211_A	1214_S	1.171	0.68
351_E	354_G	1.169	0.68
1118_D	1122_T	1.169	0.68
42_D	152_H	1.167	0.68
1056_M	1091_C	1.167	0.68
1041_K	1068_I	1.165	0.68
962_D	978_R	1.164	0.67
234_P	238_F	1.162	0.67
1159_R	1163_D	1.160	0.67
696_A	804_A	1.160	0.67
653_V	669_M	1.159	0.67
741_M	750_D	1.158	0.67
391_T	643_L	1.155	0.67
411_I	1056_M	1.155	0.67
1212_L	1217_L	1.151	0.67
78_T	109_G	1.150	0.67
1056_M	1134_V	1.148	0.66
517_S	602_L	1.147	0.66
937_E	940_E	1.147	0.66
15_R	1159_R	1.145	0.66
869_A	872_A	1.144	0.66
431_N	498_L	1.144	0.66
243_N	762_E	1.143	0.66
51_E	54_Q	1.142	0.66
1200_R	1222_Y	1.142	0.66
561_P	565_E	1.141	0.66
892_V	896_E	1.140	0.66
640_V	891_L	1.137	0.66
353_F	792_R	1.134	0.65
1280_D	1288_R	1.128	0.65
29_P	123_Q	1.127	0.65
252_V	443_A	1.126	0.65
1132_L	1219_A	1.126	0.65
430_I	473_D	1.125	0.65
1182_L	1255_T	1.125	0.65
437_V	955_V	1.124	0.65
1209_L	1213_E	1.123	0.65
977_S	980_T	1.122	0.65
357_E	463_A	1.121	0.65
659_S	1169_F	1.121	0.65
815_I	882_Y	1.120	0.64
245_F	771_T	1.120	0.64
873_L	878_K	1.117	0.64
1150_G	1154_W	1.116	0.64
553_L	563_F	1.115	0.64
1052_S	1134_V	1.114	0.64
661_T	1089_V	1.113	0.64
32_N	115_E	1.110	0.64
225_D	232_Q	1.109	0.64
1086_H	1128_Q	1.108	0.64
703_V	855_A	1.108	0.64
694_A	723_I	1.107	0.64
498_L	556_A	1.106	0.63
825_A	957_Q	1.106	0.63
461_S	468_A	1.106	0.63
626_L	849_Q	1.104	0.63
342_I	345_F	1.103	0.63
1217_L	1250_E	1.103	0.63
121_N	125_Q	1.101	0.63
679_N	884_D	1.099	0.63
1063_A	1281_G	1.098	0.63
435_K	576_V	1.096	0.63
287_A	685_A	1.096	0.63
445_N	1052_S	1.096	0.63
27_R	30_V	1.096	0.63
990_W	1006_H	1.095	0.63
529_E	591_R	1.094	0.63
227_V	615_D	1.093	0.63
891_L	966_I	1.090	0.62
959_V	962_D	1.089	0.62
633_I	920_L	1.088	0.62
137_E	463_A	1.087	0.62
274_D	422_A	1.082	0.62
1065_F	1284_M	1.079	0.61
824_N	932_R	1.079	0.61
643_L	988_T	1.078	0.61
679_N	726_T	1.077	0.61
358_R	1256_I	1.072	0.61
274_D	277_T	1.071	0.61
744_A	779_M	1.070	0.61
867_Y	870_I	1.070	0.61
436_L	525_F	1.070	0.61
1028_D	1285_R	1.069	0.61
48_N	51_E	1.068	0.61
240_M	243_N	1.068	0.61
263_M	289_I	1.068	0.61
871_Q	875_A	1.065	0.60
565_E	569_R	1.064	0.60
1223_V	1230_T	1.064	0.60
430_I	499_F	1.064	0.60
637_V	974_F	1.062	0.60
1089_V	1132_L	1.062	0.60
421_R	438_V	1.061	0.60
713_R	860_V	1.061	0.60
437_V	574_Y	1.055	0.60
289_I	685_A	1.054	0.60
438_V	461_S	1.054	0.60
974_F	981_L	1.053	0.60
565_E	568_K	1.052	0.59
1130_L	1180_L	1.052	0.59
302_I	1140_M	1.049	0.59
498_L	559_Q	1.047	0.59
1212_L	1218_V	1.046	0.59
746_H	782_K	1.045	0.59
430_I	498_L	1.045	0.59
249_P	771_T	1.044	0.59
1000_E	1004_Q	1.043	0.59
902_H	979_T	1.042	0.59
638_K	981_L	1.041	0.59
589_H	596_Q	1.038	0.58
1052_S	1192_I	1.038	0.58
976_E	980_T	1.038	0.58
1224_D	1230_T	1.037	0.58
533_D	547_S	1.037	0.58
1032_P	1037_G	1.037	0.58
251_H	264_E	1.036	0.58
261_A	326_A	1.035	0.58
898_A	903_C	1.035	0.58
189_Y	610_P	1.034	0.58
499_F	517_S	1.034	0.58
1026_N	1278_G	1.034	0.58
394_E	702_P	1.033	0.58
74_L	111_A	1.033	0.58
208_M	607_G	1.031	0.58
736_L	772_I	1.030	0.58
937_E	941_S	1.027	0.58
1145_R	1156_R	1.025	0.57
341_R	353_F	1.024	0.57
1169_F	1269_S	1.024	0.57
990_W	1007_Q	1.024	0.57
716_V	760_V	1.022	0.57
675_V	902_H	1.019	0.57
203_D	538_S	1.019	0.57
114_I	127_V	1.018	0.57
1070_V	1081_G	1.017	0.57
254_S	461_S	1.017	0.57
24_Q	28_L	1.017	0.57
342_I	988_T	1.014	0.57
1061_H	1067_A	1.012	0.56
1201_V	1241_P	1.011	0.56
411_I	799_S	1.008	0.56
1285_R	1288_R	1.007	0.56
348_P	639_R	1.004	0.56
1148_I	1254_V	1.004	0.56
341_R	346_E	0.998	0.55
137_E	1072_M	0.998	0.55
638_K	642_H	0.997	0.55
320_G	328_P	0.997	0.55
801_V	943_L	0.996	0.55
706_L	852_D	0.994	0.55
1061_H	1066_D	0.994	0.55
34_Y	113_Y	0.993	0.55
410_P	993_Q	0.991	0.55
431_N	556_A	0.990	0.55
160_S	200_N	0.988	0.55
234_P	244_T	0.987	0.55
1157_F	1201_V	0.987	0.55
196_K	603_D	0.986	0.54
1117_R	1121_A	0.986	0.54
36_E	113_Y	0.984	0.54
466_D	647_A	0.983	0.54
159_T	203_D	0.981	0.54
245_F	249_P	0.977	0.54
516_V	525_F	0.977	0.54
1209_L	1242_N	0.976	0.54
724_A	871_Q	0.976	0.54
1172_V	1190_M	0.976	0.54
370_P	655_I	0.976	0.54
1153_L	1205_D	0.974	0.54
251_H	733_R	0.974	0.54
743_A	750_D	0.974	0.54
42_D	148_Q	0.973	0.54
1042_V	1087_A	0.971	0.53
1274_P	1277_W	0.971	0.53
852_D	855_A	0.970	0.53
1143_N	1156_R	0.970	0.53
706_L	710_A	0.970	0.53
146_A	149_L	0.969	0.53
235_K	241_I	0.968	0.53
659_S	1167_A	0.968	0.53
1222_Y	1245_T	0.968	0.53
1281_G	1285_R	0.967	0.53
589_H	594_D	0.967	0.53
742_A	745_G	0.965	0.53
1172_V	1261_P	0.965	0.53
259_N	755_E	0.963	0.53
232_Q	241_I	0.962	0.53
1192_I	1261_P	0.961	0.53
829_I	943_L	0.960	0.53
234_P	240_M	0.958	0.52
153_H	156_T	0.957	0.52
879_L	948_L	0.956	0.52
720_L	768_L	0.955	0.52
796_S	803_S	0.953	0.52
443_A	547_S	0.953	0.52
883_H	893_T	0.953	0.52
420_I	424_H	0.949	0.52
727_Q	813_H	0.948	0.52
978_R	982_R	0.946	0.51
637_V	892_V	0.945	0.51
488_C	495_N	0.944	0.51
809_E	813_H	0.944	0.51
54_Q	59_L	0.943	0.51
263_M	291_M	0.942	0.51
1079_R	1083_E	0.940	0.51
646_V	718_E	0.940	0.51
1000_E	1003_D	0.937	0.51
665_A	684_T	0.935	0.51
940_E	954_Y	0.935	0.51
305_W	475_P	0.935	0.51
616_V	1152_E	0.935	0.51
883_H	985_W	0.935	0.51
64_A	145_D	0.934	0.50
369_G	645_T	0.934	0.50
366_M	410_P	0.934	0.50
869_A	876_Q	0.933	0.50
439_L	481_C	0.933	0.50
667_D	1167_A	0.932	0.50
363_L	367_T	0.931	0.50
702_P	705_L	0.930	0.50
438_V	468_A	0.928	0.50
1246_A	1256_I	0.928	0.50
738_A	772_I	0.928	0.50
232_Q	240_M	0.925	0.50
700_R	703_V	0.925	0.50
869_A	873_L	0.924	0.50
1174_V	1227_G	0.923	0.50
650_T	986_A	0.922	0.50
429_E	499_F	0.921	0.49
530_I	695_M	0.919	0.49
254_S	261_A	0.917	0.49
37_Y	110_V	0.916	0.49
938_A	941_S	0.915	0.49
436_L	516_V	0.914	0.49
229_D	241_I	0.914	0.49
865_G	947_G	0.914	0.49
235_K	246_E	0.913	0.49
1147_L	1249_T	0.913	0.49
1207_A	1210_A	0.913	0.49
341_R	352_D	0.912	0.49
648_E	982_R	0.911	0.49
445_N	1164_R	0.908	0.48
52_H	56_E	0.907	0.48
185_D	608_K	0.906	0.48
995_L	999_P	0.905	0.48
1072_M	1096_Y	0.905	0.48
1261_P	1278_G	0.904	0.48
646_V	888_G	0.904	0.48
31_H	115_E	0.901	0.48
473_D	533_D	0.901	0.48
663_M	687_L	0.900	0.48
98_C	1109_S	0.899	0.48
1151_S	1249_T	0.898	0.48
694_A	814_T	0.897	0.48
230_G	240_M	0.896	0.48
269_G	686_S	0.896	0.48
586_L	600_L	0.896	0.48
530_I	542_I	0.896	0.48
1023_F	1282_P	0.895	0.47
1131_A	1249_T	0.895	0.47
541_E	1193_A	0.894	0.47
399_H	1195_S	0.893	0.47
664_V	1165_F	0.892	0.47
1231_E	1245_T	0.891	0.47
1021_L	1188_S	0.890	0.47
833_K	859_D	0.890	0.47
24_Q	27_R	0.888	0.47
821_T	958_A	0.887	0.47
694_A	728_I	0.887	0.47
643_L	892_V	0.885	0.47
827_L	939_V	0.883	0.47
423_D	493_D	0.882	0.46
1032_P	1035_A	0.881	0.46
303_S	498_L	0.880	0.46
1046_R	1069_D	0.880	0.46
821_T	903_C	0.879	0.46
899_F	985_W	0.879	0.46
959_V	965_V	0.878	0.46
740_W	748_G	0.878	0.46
661_T	1165_F	0.877	0.46
849_Q	917_L	0.875	0.46
736_L	770_L	0.873	0.46
878_K	943_L	0.872	0.46
20_L	32_N	0.871	0.46
223_N	255_A	0.870	0.46
623_G	852_D	0.868	0.45
290_L	735_K	0.866	0.45
269_G	272_F	0.866	0.45
154_Q	157_P	0.866	0.45
230_G	233_Q	0.865	0.45
1082_L	1088_L	0.865	0.45
230_G	244_T	0.865	0.45
204_I	540_L	0.863	0.45
991_Q	1003_D	0.863	0.45
1031_A	1034_I	0.863	0.45
159_T	178_L	0.863	0.45
646_V	892_V	0.862	0.45
1035_A	1038_A	0.862	0.45
499_F	515_L	0.862	0.45
228_I	231_E	0.860	0.45
1044_V	1091_C	0.860	0.45
373_G	478_E	0.860	0.45
944_A	949_A	0.860	0.45
1217_L	1249_T	0.859	0.45
741_M	745_G	0.858	0.45
387_G	1144_L	0.858	0.45
458_S	468_A	0.858	0.45
941_S	945_Q	0.857	0.45
122_E	125_Q	0.856	0.44
556_A	559_Q	0.854	0.44
815_I	879_L	0.852	0.44
350_E	400_N	0.852	0.44
871_Q	874_V	0.851	0.44
700_R	718_E	0.851	0.44
22_R	26_A	0.850	0.44
1225_N	1229_V	0.848	0.44
228_I	233_Q	0.848	0.44
820_S	956_G	0.847	0.44
857_V	863_L	0.844	0.44
782_K	793_E	0.843	0.44
1059_A	1265_F	0.842	0.43
462_D	540_L	0.841	0.43
388_Y	697_I	0.841	0.43
715_A	772_I	0.839	0.43
421_R	468_A	0.838	0.43
568_K	574_Y	0.838	0.43
600_L	796_S	0.837	0.43
9_P	34_Y	0.837	0.43
1021_L	1025_I	0.836	0.43
539_P	590_D	0.835	0.43
6_R	34_Y	0.835	0.43
672_P	901_G	0.835	0.43
1267_T	1278_G	0.835	0.43
1206_A	1214_S	0.834	0.43
902_H	1009_K	0.833	0.43
254_S	421_R	0.833	0.43
231_E	240_M	0.832	0.43
238_F	242_K	0.832	0.43
326_A	1257_M	0.831	0.43
390_R	677_V	0.831	0.43
873_L	929_I	0.830	0.43
248_T	732_K	0.829	0.42
387_G	683_T	0.828	0.42
270_R	486_D	0.828	0.42
905_I	958_A	0.828	0.42
74_L	113_Y	0.826	0.42
825_A	931_V	0.825	0.42
1089_V	1195_S	0.825	0.42
261_A	606_L	0.825	0.42
221_I	744_A	0.824	0.42
919_A	953_H	0.822	0.42
675_V	982_R	0.822	0.42
857_V	860_V	0.821	0.42
261_A	712_A	0.821	0.42
287_A	1141_M	0.820	0.42
1132_L	1283_W	0.819	0.42
245_F	248_T	0.815	0.41
711_S	756_A	0.813	0.41
228_I	244_T	0.813	0.41
1111_L	1120_F	0.811	0.41
19_L	131_L	0.810	0.41
443_A	523_G	0.810	0.41
350_E	354_G	0.809	0.41
81_P	140_F	0.809	0.41
345_F	991_Q	0.809	0.41
169_Q	173_D	0.809	0.41
862_Q	869_A	0.808	0.41
428_G	498_L	0.808	0.41
872_A	946_H	0.807	0.41
247_T	250_D	0.807	0.41
386_N	1195_S	0.807	0.41
282_F	1061_H	0.806	0.41
287_A	419_N	0.806	0.41
1130_L	1181_L	0.806	0.41
658_R	664_V	0.803	0.40
539_P	597_P	0.802	0.40
14_F	1163_D	0.801	0.40
41_A	95_A	0.800	0.40
232_Q	244_T	0.799	0.40
863_L	867_Y	0.798	0.40
413_L	602_L	0.797	0.40
1211_A	1250_E	0.797	0.40
899_F	982_R	0.797	0.40
265_G	271_Y	0.796	0.40
202_N	567_C	0.795	0.40
680_C	1109_S	0.795	0.40
734_I	981_L	0.794	0.40
1131_A	1251_S	0.794	0.40
1079_R	1115_R	0.794	0.40
582_E	1192_I	0.793	0.40
1080_T	1084_D	0.792	0.40
49_D	53_A	0.791	0.40
939_V	948_L	0.791	0.40
607_G	610_P	0.789	0.39
1182_L	1286_I	0.788	0.39
399_H	406_G	0.787	0.39
1170_S	1237_P	0.786	0.39
1169_F	1268_V	0.784	0.39
1173_E	1221_R	0.784	0.39
252_V	771_T	0.783	0.39
387_G	681_A	0.783	0.39
1052_S	1281_G	0.782	0.39
708_F	756_A	0.782	0.39
227_V	606_L	0.782	0.39
1136_N	1139_Q	0.782	0.39
475_P	712_A	0.781	0.39
619_L	749_E	0.781	0.39
823_D	958_A	0.780	0.39
499_F	540_L	0.780	0.39
1087_A	1181_L	0.780	0.39
1043_A	1082_L	0.780	0.39
727_Q	874_V	0.780	0.39
269_G	689_S	0.780	0.39
400_N	408_H	0.779	0.39
12_S	1159_R	0.778	0.39
724_A	731_I	0.778	0.39
861_A	868_D	0.778	0.39
1178_P	1217_L	0.775	0.38
1191_P	1259_P	0.775	0.38
192_D	1118_D	0.775	0.38
186_E	220_K	0.774	0.38
879_L	882_Y	0.774	0.38
867_Y	871_Q	0.772	0.38
517_S	603_D	0.772	0.38
1268_V	1273_H	0.771	0.38
700_R	887_D	0.770	0.38
445_N	648_E	0.770	0.38
149_L	536_G	0.769	0.38
254_S	435_K	0.769	0.38
263_M	1052_S	0.768	0.38
577_I	691_Y	0.768	0.38
994_R	1007_Q	0.766	0.38
494_A	829_I	0.765	0.38
257_K	260_A	0.765	0.38
164_L	167_G	0.765	0.38
235_K	244_T	0.765	0.38
675_V	985_W	0.764	0.38
128_T	132_H	0.762	0.37
1192_I	1278_G	0.761	0.37
248_T	251_H	0.761	0.37
1006_H	1010_S	0.760	0.37
499_F	779_M	0.760	0.37
269_G	282_F	0.759	0.37
638_K	976_E	0.759	0.37
125_Q	128_T	0.759	0.37
1004_Q	1232_T	0.757	0.37
75_L	127_V	0.757	0.37
96_H	101_Q	0.754	0.37
202_N	1088_L	0.754	0.37
962_D	977_S	0.753	0.37
634_A	976_E	0.753	0.37
906_D	918_A	0.753	0.37
762_E	770_L	0.753	0.37
265_G	270_R	0.753	0.37
1196_H	1238_N	0.753	0.37
661_T	1052_S	0.753	0.37
174_A	700_R	0.751	0.37
438_V	533_D	0.750	0.37
660_V	1193_A	0.750	0.37
437_V	560_L	0.749	0.37
1149_P	1155_P	0.746	0.36
175_N	187_I	0.744	0.36
1116_V	1119_E	0.744	0.36
1038_A	1174_V	0.744	0.36
712_A	1175_T	0.743	0.36
621_A	706_L	0.743	0.36
485_I	500_I	0.742	0.36
1086_H	1195_S	0.742	0.36
254_S	260_A	0.741	0.36
894_L	955_V	0.740	0.36
1182_L	1246_A	0.740	0.36
137_E	606_L	0.740	0.36
406_G	699_E	0.739	0.36
1104_E	1156_R	0.739	0.36
81_P	1116_V	0.738	0.36
360_V	779_M	0.738	0.36
432_V	865_G	0.737	0.36
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184_E	188_D	0.737	0.36
355_K	359_I	0.736	0.36
320_G	482_Q	0.736	0.36
1229_V	1243_G	0.734	0.35
172_I	970_G	0.733	0.35
704_A	757_V	0.732	0.35
704_A	711_S	0.732	0.35
473_D	803_S	0.732	0.35
8_S	39_H	0.731	0.35
691_Y	809_E	0.730	0.35
716_V	802_I	0.730	0.35
1206_A	1242_N	0.730	0.35
1209_L	1244_I	0.729	0.35
1172_V	1220_L	0.729	0.35
537_M	577_I	0.728	0.35
273_A	305_W	0.728	0.35
1135_C	1139_Q	0.728	0.35
718_E	886_S	0.727	0.35
692_G	808_V	0.726	0.35
827_L	864_K	0.725	0.35
461_S	533_D	0.724	0.35
865_G	869_A	0.724	0.35
124_W	128_T	0.724	0.35
47_L	51_E	0.723	0.35
720_L	728_I	0.723	0.35
26_A	30_V	0.722	0.35
727_Q	875_A	0.722	0.35
823_D	903_C	0.722	0.35
850_L	1053_H	0.722	0.35
9_P	36_E	0.722	0.35
661_T	687_L	0.722	0.35
190_L	607_G	0.722	0.35
931_V	954_Y	0.722	0.35
261_A	756_A	0.722	0.35
153_H	598_I	0.721	0.35
928_V	932_R	0.721	0.35
537_M	744_A	0.721	0.35
169_Q	558_D	0.719	0.34
374_A	782_K	0.719	0.34
517_S	540_L	0.718	0.34
630_G	849_Q	0.718	0.34
724_A	927_A	0.718	0.34
368_E	371_L	0.718	0.34
903_C	984_W	0.718	0.34
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1044_V	1247_V	0.715	0.34
1172_V	1278_G	0.713	0.34
646_V	887_D	0.713	0.34
233_Q	245_F	0.712	0.34
1175_T	1245_T	0.712	0.34
726_T	874_V	0.712	0.34
58_L	801_V	0.712	0.34
324_R	804_A	0.711	0.34
585_H	601_P	0.710	0.34
872_A	942_V	0.710	0.34
303_S	733_R	0.709	0.34
120_T	659_S	0.708	0.34
257_K	326_A	0.708	0.34
1111_L	1144_L	0.708	0.34
615_D	955_V	0.708	0.34
908_D	970_G	0.707	0.34
437_V	567_C	0.707	0.34
457_A	475_P	0.707	0.34
1025_I	1278_G	0.706	0.34
1192_I	1259_P	0.705	0.33
742_A	779_M	0.705	0.33
653_V	985_W	0.705	0.33
1209_L	1218_V	0.705	0.33
1126_R	1129_T	0.702	0.33
456_M	461_S	0.702	0.33
714_L	925_L	0.702	0.33
628_R	631_I	0.702	0.33
1224_D	1235_A	0.702	0.33
723_I	880_L	0.702	0.33
609_T	612_M	0.701	0.33
466_D	476_E	0.701	0.33
421_R	461_S	0.701	0.33
54_Q	61_Y	0.700	0.33
461_S	481_C	0.700	0.33
1142_S	1148_I	0.700	0.33
808_V	814_T	0.700	0.33
33_I	39_H	0.699	0.33
312_S	376_F	0.698	0.33
534_E	572_A	0.698	0.33
567_C	574_Y	0.698	0.33
666_R	678_A	0.698	0.33
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439_L	567_C	0.697	0.33
1089_V	1194_V	0.697	0.33
562_L	566_L	0.696	0.33
166_Q	169_Q	0.695	0.33
725_A	814_T	0.695	0.33
567_C	575_A	0.695	0.33
1096_Y	1110_I	0.694	0.33
650_T	808_V	0.694	0.33
861_A	864_K	0.694	0.33
285_E	1246_A	0.693	0.33
796_S	1246_A	0.693	0.33
475_P	961_G	0.693	0.33
826_L	931_V	0.693	0.33
1178_P	1249_T	0.692	0.33
239_K	243_N	0.691	0.33
720_L	863_L	0.691	0.33
436_L	503_V	0.691	0.33
457_A	782_K	0.691	0.33
1003_D	1006_H	0.691	0.33
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1168_R	1233_Y	0.690	0.32
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512_M	525_F	0.688	0.32
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516_V	523_G	0.687	0.32
1094_F	1135_C	0.687	0.32
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943_L	946_H	0.662	0.31
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1035_A	1039_R	0.653	0.30
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726_T	817_P	0.647	0.30
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532_S	535_P	0.645	0.29
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755_E	758_K	0.645	0.29
1153_L	1208_H	0.645	0.29
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288_H	420_I	0.644	0.29
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194_F	1207_A	0.644	0.29
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327_K	1053_H	0.643	0.29
681_A	1144_L	0.643	0.29
168_R	184_E	0.643	0.29
849_Q	852_D	0.643	0.29
637_V	966_I	0.642	0.29
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430_I	803_S	0.641	0.29
147_E	154_Q	0.640	0.29
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399_H	699_E	0.639	0.29
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648_E	752_G	0.638	0.29
821_T	906_D	0.638	0.29
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1193_A	1259_P	0.633	0.29
532_S	542_I	0.633	0.29
417_I	805_F	0.633	0.29
106_L	1275_E	0.633	0.29
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1212_L	1216_G	0.629	0.28
1169_F	1273_H	0.628	0.28
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1192_I	1246_A	0.627	0.28
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1042_V	1060_F	0.627	0.28
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251_H	807_R	0.626	0.28
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1052_S	1165_F	0.626	0.28
706_L	850_L	0.625	0.28
418_G	439_L	0.625	0.28
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400_N	406_G	0.624	0.28
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498_L	517_S	0.615	0.28
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515_L	525_F	0.615	0.28
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916_R	973_V	0.613	0.27
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743_A	748_G	0.602	0.27
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516_V	794_M	0.600	0.27
1238_N	1258_M	0.599	0.27
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526_E	815_I	0.598	0.27
621_A	855_A	0.598	0.27
230_G	241_I	0.598	0.27
1130_L	1222_Y	0.597	0.26
49_D	558_D	0.597	0.26
239_K	242_K	0.596	0.26
617_Q	747_P	0.595	0.26
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280_Y	283_H	0.592	0.26
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269_G	752_G	0.588	0.26
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1186_V	1190_M	0.505	0.21
399_H	534_E	0.505	0.21
1043_A	1081_G	0.505	0.21
737_S	1194_V	0.505	0.21
437_V	475_P	0.504	0.21
24_Q	732_K	0.504	0.21
20_L	33_I	0.504	0.21
418_G	496_P	0.504	0.21
585_H	796_S	0.503	0.21
939_V	942_V	0.503	0.21
740_W	896_E	0.503	0.21
860_V	864_K	0.503	0.21
347_Q	798_L	0.503	0.21
872_A	944_A	0.503	0.21
1092_G	1196_H	0.503	0.21
826_L	955_V	0.503	0.21
908_D	963_R	0.503	0.21
229_D	236_S	0.503	0.21
235_K	239_K	0.503	0.21
418_G	732_K	0.503	0.21
97_N	1229_V	0.503	0.21
349_W	991_Q	0.502	0.21
292_K	547_S	0.502	0.21
350_E	1126_R	0.502	0.21
253_L	286_P	0.502	0.21
206_L	209_F	0.502	0.21
31_H	118_T	0.501	0.21
1000_E	1183_Q	0.501	0.21
647_A	745_G	0.501	0.21
681_A	695_M	0.501	0.21
161_V	481_C	0.501	0.21
892_V	1054_V	0.501	0.21
51_E	929_I	0.501	0.21
873_L	876_Q	0.500	0.21
661_T	761_G	0.500	0.21
1232_T	1235_A	0.500	0.21

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3viuA	1	0.5382	100	0.716	Contact Map
1vk3A	1	0.4486	100	0.775	Contact Map
3fd5A	2	0.2394	100	0.947	Contact Map
3d54D	1	0.1629	100	0.948	Contact Map
3u0oA	2	0.2247	100	0.949	Contact Map
2zodA	2	0.2263	100	0.95	Contact Map
2v9yA	2	0.2154	99.9	0.95	Contact Map
3vtiC	2	0.2263	99.9	0.951	Contact Map
2rb9A	2	0.2324	99.9	0.951	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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