GREMLIN Database
GLGX - Glycogen debranching enzyme
UniProt: P15067 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10381
Length: 657 (538)
Sequences: 8177 (5472)
Seq/√Len: 235.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
177_K243_E4.2911.00
177_K246_D4.1911.00
250_A253_K4.0921.00
186_N254_A4.0331.00
553_A638_N3.9801.00
49_L59_G3.4911.00
190_Q552_A3.4381.00
189_K254_A3.3351.00
244_F248_I3.2881.00
196_L251_L3.1511.00
519_G547_L3.1111.00
245_R327_T3.0431.00
206_S217_N2.8551.00
138_W329_H2.8371.00
358_Q389_F2.8041.00
314_V352_P2.7581.00
556_H560_R2.7211.00
162_T183_V2.6541.00
505_L592_W2.6441.00
323_Y328_C2.5841.00
500_L551_T2.5681.00
25_L282_I2.5061.00
235_C243_E2.4901.00
250_A254_A2.4731.00
20_G60_Y2.4411.00
440_T516_D2.3841.00
246_D250_A2.3671.00
185_I254_A2.2741.00
576_N579_W2.2611.00
242_D245_R2.2571.00
325_V366_V2.2541.00
198_L201_V2.2161.00
244_F330_V2.1701.00
264_L320_C2.1561.00
156_A161_L2.1331.00
198_L247_A2.1331.00
32_R48_D2.0741.00
21_V64_A2.0521.00
505_L609_I2.0291.00
180_G246_D2.0181.00
47_Y59_G2.0151.00
36_C91_L1.9971.00
150_S565_V1.9761.00
267_S288_Y1.9741.00
533_N536_T1.9741.00
151_T195_A1.9581.00
181_H250_A1.9531.00
315_D319_A1.9491.00
488_L491_R1.9431.00
227_F320_C1.9091.00
177_K180_G1.9091.00
549_A552_A1.9041.00
247_A251_L1.8971.00
243_E246_D1.8671.00
518_H538_L1.8651.00
141_D329_H1.8591.00
64_A68_L1.8591.00
179_L247_A1.8441.00
24_T58_H1.8371.00
101_D105_K1.8341.00
326_E362_V1.8241.00
32_R75_H1.8151.00
34_E73_R1.8121.00
252_H331_D1.8041.00
201_V244_F1.7981.00
34_E75_H1.7961.00
357_I366_V1.7961.00
244_F247_A1.7761.00
14_A21_V1.7611.00
504_L555_I1.7551.00
529_Y532_D1.7551.00
553_A556_H1.7431.00
576_N581_N1.7411.00
557_L630_I1.7391.00
152_I555_I1.7351.00
190_Q548_T1.7351.00
158_V179_L1.7321.00
23_F72_Y1.7321.00
579_W582_R1.7271.00
523_H531_Q1.7161.00
65_R68_L1.7131.00
188_L196_L1.7131.00
629_A632_P1.7131.00
156_A188_L1.7031.00
44_E73_R1.6971.00
249_K253_K1.6941.00
545_S549_A1.6841.00
16_Y21_V1.6481.00
148_W151_T1.6481.00
269_E297_H1.6431.00
323_Y327_T1.6361.00
69_R101_D1.6321.00
33_V74_V1.6311.00
348_R351_A1.6301.00
584_A587_L1.6241.00
73_R91_L1.6181.00
548_T552_A1.6071.00
188_L256_I1.5981.00
25_L33_V1.5911.00
74_V282_I1.5801.00
31_E77_P1.5761.00
180_G250_A1.5711.00
17_D60_Y1.5611.00
241_L328_C1.5571.00
146_T151_T1.5551.00
489_V521_S1.5451.00
34_E48_D1.5221.00
570_W575_G1.5191.00
153_I437_N1.5161.00
537_W540_W1.5051.00
561_I607_F1.5001.00
322_R356_A1.4951.00
306_L313_V1.4931.00
16_Y66_P1.4931.00
25_L74_V1.4841.00
100_I225_A1.4831.00
131_V249_K1.4831.00
291_R295_D1.4831.00
448_R496_I1.4741.00
38_F68_L1.4731.00
202_A320_C1.4641.00
172_I178_A1.4571.00
356_A359_N1.4511.00
578_R595_G1.4481.00
298_N301_G1.4461.00
76_G90_K1.4401.00
93_I100_I1.4391.00
31_E75_H1.4311.00
325_V357_I1.4291.00
553_A637_D1.4291.00
259_I369_I1.4151.00
550_F633_F1.4041.00
561_I605_D1.3961.00
322_R326_E1.3901.00
540_W543_A1.3901.00
161_L184_M1.3901.00
500_L512_L1.3891.00
354_F358_Q1.3821.00
321_L353_L1.3811.00
581_N591_E1.3791.00
203_Q231_P1.3781.00
307_N310_H1.3641.00
34_E46_R1.3641.00
396_F506_S1.3611.00
22_N60_Y1.3601.00
549_A553_A1.3581.00
496_I519_G1.3491.00
156_A179_L1.3441.00
229_L244_F1.3431.00
188_L192_G1.3381.00
412_G586_P1.3341.00
139_E249_K1.3311.00
195_A259_I1.3301.00
36_C73_R1.3251.00
353_L368_L1.3251.00
24_T56_I1.3251.00
156_A196_L1.3241.00
514_A538_L1.3191.00
539_D542_Q1.3171.00
402_R417_R1.3151.00
536_T540_W1.3131.00
159_K163_Y1.3131.00
203_Q230_H1.3121.00
185_I250_A1.3021.00
136_Y246_D1.3001.00
610_A620_I1.2991.00
398_D402_R1.2911.00
97_A100_I1.2791.00
147_P150_S1.2721.00
352_P356_A1.2691.00
593_Q608_L1.2591.00
421_S506_S1.2591.00
46_R73_R1.2561.00
158_V198_L1.2521.00
186_N190_Q1.2521.00
318_S353_L1.2471.00
497_H550_F1.2471.00
355_T383_G1.2451.00
76_G82_E1.2441.00
550_F554_L1.2391.00
404_W499_L1.2341.00
251_L256_I1.2331.00
414_F417_R1.2321.00
21_V65_R1.2311.00
51_G54_G1.2301.00
229_L324_W1.2271.00
100_I228_A1.2271.00
262_I321_L1.2261.00
175_T178_A1.2211.00
413_A416_G1.2161.00
512_L516_D1.2151.00
176_Y234_A1.2131.00
71_G91_L1.2131.00
279_L316_Y1.2111.00
168_I173_R1.2091.00
146_T195_A1.2061.00
22_N58_H1.2051.00
500_L554_L1.2041.00
312_A315_D1.2031.00
151_T194_T1.2031.00
448_R452_C1.2001.00
176_Y229_L1.1951.00
537_W541_S1.1921.00
151_T367_K1.1911.00
170_V173_R1.1901.00
450_C454_N1.1901.00
579_W584_A1.1861.00
535_L538_L1.1801.00
543_A548_T1.1761.00
11_P24_T1.1751.00
422_S432_P1.1731.00
47_Y61_L1.1731.00
352_P355_T1.1711.00
438_L441_A1.1711.00
325_V363_L1.1711.00
576_N580_L1.1671.00
530_C533_N1.1641.00
136_Y139_E1.1581.00
202_A223_P1.1541.00
96_C288_Y1.1521.00
557_L631_P1.1511.00
131_V134_D1.1511.00
552_A556_H1.1431.00
185_I251_L1.1421.00
195_A257_E1.1391.00
497_H546_G1.1381.00
38_F69_R1.1351.00
186_N189_K1.1351.00
197_E392_W1.1301.00
61_L64_A1.1251.00
187_Y548_T1.1231.00
402_R405_L1.1221.00
406_H410_P1.1191.00
354_F368_L1.1171.00
588_S614_T1.1161.00
581_N584_A1.1151.00
493_R497_H1.1101.00
550_F631_P1.1101.00
12_L56_I1.1071.00
201_V260_L1.1071.00
578_R582_R1.1051.00
35_L59_G1.1051.00
191_L548_T1.1041.00
591_E594_N1.1021.00
412_G415_A1.1021.00
168_I172_I1.1011.00
179_L198_L1.0981.00
400_A499_L1.0891.00
99_Q111_H1.0861.00
353_L357_I1.0861.00
411_L414_F1.0811.00
578_R581_N1.0811.00
153_I436_I1.0751.00
296_Y301_G1.0711.00
400_A502_T1.0691.00
308_L317_A1.0671.00
501_T550_F1.0621.00
184_M187_Y1.0581.00
227_F319_A1.0541.00
305_T340_V1.0501.00
452_C500_L1.0491.00
169_P172_I1.0481.00
26_F312_A1.0461.00
350_D354_F1.0441.00
181_H186_N1.0431.00
146_T150_S1.0351.00
161_L179_L1.0331.00
504_L512_L1.0321.00
399_A413_A1.0321.00
440_T499_L1.0311.00
622_L627_W1.0301.00
322_R363_L1.0301.00
244_F260_L1.0301.00
140_D329_H1.0291.00
12_L24_T1.0291.00
152_I559_K1.0261.00
229_L323_Y1.0251.00
14_A23_F1.0251.00
491_R495_S1.0201.00
555_I559_K1.0171.00
244_F328_C1.0171.00
436_I510_P1.0141.00
529_Y533_N1.0131.00
156_A514_A1.0111.00
169_P181_H1.0071.00
417_R423_D1.0061.00
139_E142_A1.0031.00
512_L551_T1.0021.00
93_I97_A1.0021.00
493_R496_I0.9971.00
403_F406_H0.9951.00
177_K181_H0.9901.00
383_G386_P0.9851.00
227_F316_Y0.9821.00
37_V47_Y0.9821.00
159_K233_Y0.9811.00
536_T539_D0.9761.00
498_A611_I0.9751.00
29_H285_R0.9741.00
297_H302_C0.9731.00
160_G218_Y0.9651.00
280_R304_N0.9611.00
545_S548_T0.9611.00
11_P22_N0.9591.00
147_P151_T0.9591.00
535_L540_W0.9591.00
226_M316_Y0.9591.00
225_A228_A0.9581.00
50_P58_H0.9571.00
295_D344_T0.9551.00
206_S222_N0.9521.00
322_R362_V0.9491.00
161_L187_Y0.9471.00
179_L251_L0.9451.00
393_N435_A0.9431.00
33_V282_I0.9431.00
148_W390_A0.9411.00
94_D97_A0.9401.00
573_G579_W0.9401.00
321_L333_F0.9371.00
547_L550_F0.9361.00
378_G381_Q0.9351.00
563_A607_F0.9351.00
576_N582_R0.9351.00
411_L420_A0.9341.00
348_R352_P0.9341.00
68_L110_L0.9321.00
357_I368_L0.9301.00
534_Q537_W0.9291.00
158_V176_Y0.9291.00
589_T593_Q0.9281.00
17_D22_N0.9261.00
181_H246_D0.9241.00
557_L561_I0.9191.00
298_N340_V0.9191.00
535_L543_A0.9191.00
531_Q535_L0.9111.00
532_D535_L0.9091.00
279_L282_I0.9081.00
162_T174_G0.9071.00
103_E207_E0.9041.00
223_P226_M0.9041.00
290_I295_D0.9031.00
23_F35_L0.9021.00
407_Y410_P0.9011.00
318_S322_R0.9001.00
226_M306_L0.9001.00
416_G420_A0.9001.00
39_D42_G0.9001.00
97_A107_N0.8981.00
326_E363_L0.8961.00
522_Q539_D0.8940.99
28_A55_D0.8890.99
260_L330_V0.8880.99
577_V582_R0.8870.99
29_H283_D0.8860.99
493_R546_G0.8850.99
530_C536_T0.8850.99
546_G549_A0.8840.99
497_H547_L0.8840.99
172_I181_H0.8830.99
607_F630_I0.8810.99
415_A420_A0.8810.99
291_R297_H0.8800.99
532_D537_W0.8790.99
494_D497_H0.8770.99
501_T611_I0.8750.99
137_D249_K0.8740.99
202_A260_L0.8720.99
129_C132_V0.8720.99
39_D43_Q0.8720.99
15_H98_R0.8700.99
489_V492_R0.8700.99
573_G576_N0.8700.99
564_L607_F0.8690.99
285_R290_I0.8680.99
136_Y329_H0.8660.99
495_S498_A0.8660.99
152_I504_L0.8660.99
500_L516_D0.8630.99
220_G233_Y0.8600.99
419_A422_S0.8550.99
406_H417_R0.8540.99
549_A637_D0.8530.99
417_R420_A0.8520.99
76_G84_H0.8510.99
414_F420_A0.8510.99
548_T551_T0.8510.99
167_E170_V0.8480.99
580_L608_L0.8470.99
629_A635_G0.8470.99
311_P315_D0.8430.99
627_W630_I0.8410.99
37_V42_G0.8400.99
351_A355_T0.8380.99
489_V493_R0.8360.99
162_T184_M0.8350.99
134_D138_W0.8350.99
188_L193_I0.8340.99
290_I296_Y0.8330.99
537_W543_A0.8330.99
64_A110_L0.8320.99
14_A72_Y0.8310.99
251_L258_V0.8310.99
523_H535_L0.8310.99
296_Y300_T0.8300.99
50_P59_G0.8300.99
500_L547_L0.8300.99
381_Q385_F0.8290.99
505_L611_I0.8290.99
98_R323_Y0.8280.99
381_Q384_N0.8280.99
411_L419_A0.8270.99
36_C46_R0.8270.99
140_D143_P0.8260.99
138_W141_D0.8260.99
202_A330_V0.8260.99
66_P111_H0.8260.99
18_G60_Y0.8250.99
501_T633_F0.8220.99
493_R547_L0.8210.99
539_D543_A0.8190.99
135_H138_W0.8180.99
298_N305_T0.8180.99
349_Q353_L0.8180.99
576_N584_A0.8130.99
532_D540_W0.8050.99
300_T340_V0.8050.99
174_G183_V0.8030.99
412_G416_G0.8020.99
84_H285_R0.8020.99
180_G243_E0.8000.99
577_V580_L0.7980.99
246_D249_K0.7960.99
318_S356_A0.7940.99
242_D246_D0.7870.99
146_T149_G0.7840.99
575_G579_W0.7820.99
355_T359_N0.7820.99
130_V242_D0.7810.99
320_C323_Y0.7810.99
300_T303_G0.7800.99
579_W583_Y0.7780.99
259_I332_G0.7770.99
53_S58_H0.7770.99
227_F323_Y0.7770.99
136_Y249_K0.7750.99
496_I547_L0.7720.99
534_Q540_W0.7690.98
581_N585_Q0.7680.98
139_E253_K0.7650.98
414_F421_S0.7590.98
281_G286_S0.7570.98
402_R407_Y0.7550.98
21_V110_L0.7550.98
98_R327_T0.7520.98
538_L543_A0.7480.98
168_I178_A0.7480.98
589_T592_W0.7470.98
418_F590_D0.7440.98
411_L421_S0.7430.98
414_F611_I0.7410.98
321_L335_F0.7410.98
176_Y247_A0.7410.98
141_D249_K0.7390.98
382_V425_F0.7380.98
194_T256_I0.7380.98
518_H548_T0.7350.98
416_G419_A0.7340.98
371_E442_H0.7340.98
40_A47_Y0.7340.98
37_V68_L0.7320.98
410_P413_A0.7310.98
156_A184_M0.7310.98
157_H199_L0.7280.98
448_R519_G0.7250.98
413_A417_R0.7240.98
567_N570_W0.7230.98
592_W595_G0.7230.98
355_T384_N0.7210.98
279_L284_N0.7210.98
248_I330_V0.7200.98
187_Y518_H0.7190.98
186_N250_A0.7180.98
505_L557_L0.7180.98
191_L555_I0.7170.98
523_H529_Y0.7160.98
35_L61_L0.7140.98
158_V201_V0.7140.98
618_T621_V0.7120.97
286_S289_W0.7110.97
523_H530_C0.7070.97
152_I193_I0.7060.97
441_A511_M0.7030.97
608_L622_L0.7020.97
133_V136_Y0.7010.97
96_C319_A0.6960.97
52_H58_H0.6960.97
241_L323_Y0.6960.97
172_I177_K0.6950.97
305_T308_L0.6940.97
70_Y75_H0.6940.97
522_Q536_T0.6930.97
540_W544_S0.6930.97
501_T505_L0.6920.97
37_V40_A0.6910.97
69_R107_N0.6900.97
325_V333_F0.6900.97
405_L450_C0.6870.97
72_Y75_H0.6870.97
590_D594_N0.6850.97
63_D66_P0.6850.97
134_D253_K0.6840.97
194_T559_K0.6840.97
496_I500_L0.6810.97
531_Q536_T0.6810.97
404_W613_A0.6810.97
580_L584_A0.6800.97
529_Y537_W0.6780.97
134_D249_K0.6780.97
267_S306_L0.6770.97
27_S30_A0.6770.97
441_A444_G0.6740.96
448_R451_V0.6720.96
75_H85_R0.6710.96
204_F207_E0.6710.96
453_F521_S0.6710.96
101_D108_P0.6700.96
168_I171_E0.6660.96
378_G385_F0.6650.96
396_F400_A0.6650.96
193_I256_I0.6650.96
136_Y140_D0.6650.96
416_G423_D0.6640.96
92_L95_P0.6640.96
141_D255_G0.6640.96
393_N437_N0.6620.96
575_G578_R0.6620.96
84_H90_K0.6620.96
440_T452_C0.6600.96
140_D253_K0.6600.96
608_L627_W0.6590.96
297_H300_T0.6590.96
529_Y534_Q0.6570.96
590_D593_Q0.6570.96
538_L542_Q0.6570.96
359_N362_V0.6560.96
11_P15_H0.6560.96
311_P314_V0.6550.96
141_D144_P0.6550.96
188_L251_L0.6540.96
245_R328_C0.6530.96
103_E173_R0.6500.96
415_A419_A0.6500.96
297_H301_G0.6490.96
77_P83_G0.6490.96
153_I259_I0.6480.96
266_H336_D0.6450.96
131_V135_H0.6430.95
15_H22_N0.6420.95
392_W511_M0.6410.95
43_Q46_R0.6400.95
284_N287_Y0.6380.95
453_F519_G0.6370.95
338_A370_A0.6370.95
531_Q534_Q0.6360.95
403_F613_A0.6350.95
36_C71_G0.6350.95
12_L96_C0.6350.95
52_H55_D0.6350.95
176_Y243_E0.6350.95
161_L540_W0.6340.95
632_P635_G0.6340.95
529_Y536_T0.6340.95
249_K329_H0.6340.95
174_G178_A0.6330.95
336_D371_E0.6330.95
196_L258_V0.6330.95
137_D140_D0.6330.95
439_V499_L0.6310.95
280_R285_R0.6310.95
502_T611_I0.6300.95
193_I517_E0.6300.95
155_E199_L0.6290.95
223_P320_C0.6290.95
150_S559_K0.6290.95
40_A43_Q0.6270.95
245_R323_Y0.6270.95
335_F368_L0.6260.95
317_A341_M0.6260.95
140_D249_K0.6250.95
499_L502_T0.6250.95
204_F223_P0.6240.95
298_N302_C0.6200.94
453_F456_K0.6200.94
291_R294_G0.6190.94
94_D103_E0.6190.94
299_W302_C0.6190.94
411_L415_A0.6170.94
154_Y517_E0.6160.94
367_K389_F0.6150.94
336_D443_D0.6140.94
348_R355_T0.6130.94
414_F418_F0.6130.94
574_D577_V0.6130.94
318_S352_P0.6110.94
27_S55_D0.6110.94
230_H233_Y0.6110.94
167_E171_E0.6090.94
541_S544_S0.6090.94
284_N289_W0.6090.94
580_L583_Y0.6080.94
48_D57_W0.6070.94
32_R73_R0.6070.94
529_Y540_W0.6070.94
436_I443_D0.6060.94
415_A418_F0.6060.94
532_D538_L0.6060.94
490_E494_D0.6040.94
349_Q354_F0.6040.94
183_V186_N0.6030.94
588_S591_E0.6020.94
414_F419_A0.6020.94
417_R421_S0.6010.93
168_I183_V0.6000.93
99_Q241_L0.6000.93
492_R521_S0.6000.93
157_H233_Y0.5980.93
296_Y299_W0.5980.93
554_L631_P0.5970.93
292_E295_D0.5960.93
618_T622_L0.5960.93
73_R85_R0.5960.93
411_L416_G0.5960.93
94_D99_Q0.5960.93
192_G556_H0.5940.93
556_H559_K0.5930.93
520_H536_T0.5930.93
447_L451_V0.5920.93
252_H258_V0.5910.93
205_A224_V0.5890.93
92_L282_I0.5880.93
172_I175_T0.5880.93
574_D582_R0.5870.93
179_L196_L0.5870.93
421_S425_F0.5870.93
532_D536_T0.5870.93
367_K390_A0.5870.93
306_L316_Y0.5860.93
141_D145_R0.5860.93
99_Q102_G0.5850.93
561_I565_V0.5850.93
415_A421_S0.5840.93
281_G284_N0.5840.93
133_V245_R0.5830.92
177_K235_C0.5830.92
440_T444_G0.5830.92
16_Y19_Q0.5820.92
412_G420_A0.5810.92
286_S310_H0.5800.92
416_G421_S0.5790.92
185_I189_K0.5790.92
582_R585_Q0.5780.92
286_S291_R0.5780.92
36_C44_E0.5770.92
518_H543_A0.5760.92
10_A327_T0.5760.92
422_S426_K0.5760.92
593_Q606_R0.5730.92
283_D289_W0.5730.92
298_N308_L0.5720.92
410_P414_F0.5700.92
257_E367_K0.5680.91
316_Y320_C0.5670.91
369_I511_M0.5670.91
279_L283_D0.5660.91
582_R586_P0.5660.91
66_P112_A0.5660.91
23_F61_L0.5650.91
199_L514_A0.5650.91
227_F264_L0.5650.91
251_L254_A0.5650.91
501_T554_L0.5630.91
529_Y535_L0.5620.91
394_D397_R0.5600.91
373_W397_R0.5580.91
551_T554_L0.5570.91
129_C133_V0.5560.91
334_R443_D0.5560.91
513_L520_H0.5550.91
72_Y96_C0.5550.91
204_F233_Y0.5530.90
533_N537_W0.5520.90
135_H329_H0.5510.90
298_N303_G0.5510.90
217_N535_L0.5500.90
43_Q47_Y0.5490.90
94_D100_I0.5480.90
27_S283_D0.5480.90
413_A422_S0.5480.90
618_T623_P0.5470.90
413_A420_A0.5460.90
502_T613_A0.5460.90
321_L357_I0.5460.90
72_Y76_G0.5450.90
299_W305_T0.5450.90
402_R410_P0.5440.90
95_P98_R0.5440.90
30_A283_D0.5440.90
169_P173_R0.5440.90
207_E268_A0.5440.90
93_I107_N0.5440.90
190_Q543_A0.5430.90
269_E302_C0.5430.90
589_T594_N0.5430.90
203_Q228_A0.5430.90
493_R519_G0.5420.89
418_F421_S0.5420.89
189_K255_G0.5410.89
290_I294_G0.5390.89
306_L341_M0.5380.89
33_V49_L0.5370.89
28_A286_S0.5370.89
228_A241_L0.5370.89
406_H414_F0.5370.89
69_R72_Y0.5360.89
224_V268_A0.5350.89
582_R590_D0.5350.89
436_I442_H0.5350.89
132_V137_D0.5350.89
187_Y543_A0.5340.89
382_V385_F0.5340.89
418_F502_T0.5340.89
66_P130_V0.5340.89
536_T542_Q0.5340.89
131_V138_W0.5340.89
520_H538_L0.5330.89
261_D334_R0.5330.89
51_G58_H0.5330.89
537_W542_Q0.5330.89
265_N337_L0.5330.89
521_S542_Q0.5320.89
614_T618_T0.5320.89
26_F310_H0.5310.89
440_T446_T0.5300.88
100_I203_Q0.5300.88
266_H334_R0.5300.88
487_D490_E0.5300.88
181_H184_M0.5290.88
156_A198_L0.5290.88
354_F388_L0.5290.88
552_A555_I0.5280.88
142_A145_R0.5270.88
402_R406_H0.5270.88
413_A421_S0.5260.88
296_Y302_C0.5260.88
498_A613_A0.5250.88
436_I440_T0.5250.88
168_I184_M0.5240.88
629_A633_F0.5240.88
203_Q232_A0.5230.88
249_K252_H0.5230.88
222_N268_A0.5230.88
35_L72_Y0.5230.88
409_L413_A0.5230.88
206_S232_A0.5220.88
354_F357_I0.5220.88
38_F42_G0.5200.87
454_N492_R0.5200.87
358_Q388_L0.5190.87
108_P112_A0.5170.87
419_A423_D0.5170.87
573_G578_R0.5160.87
593_Q612_N0.5150.87
487_D491_R0.5140.87
133_V138_W0.5130.87
314_V318_S0.5130.87
379_G382_V0.5130.87
339_A374_D0.5130.87
295_D307_N0.5120.87
553_A631_P0.5110.87
579_W592_W0.5110.87
189_K256_I0.5100.86
284_N290_I0.5100.86
138_W142_A0.5100.86
314_V348_R0.5090.86
49_L72_Y0.5070.86
68_L72_Y0.5060.86
135_H139_E0.5060.86
60_Y63_D0.5060.86
217_N534_Q0.5060.86
592_W611_I0.5050.86
189_K559_K0.5050.86
551_T555_I0.5050.86
161_L188_L0.5040.86
266_H442_H0.5040.86
33_V72_Y0.5040.86
190_Q549_A0.5030.86
261_D336_D0.5030.86
415_A422_S0.5030.86
93_I108_P0.5020.86
344_T352_P0.5020.86
575_G586_P0.5020.86
414_F425_F0.5020.86
278_S281_G0.5010.86
264_L317_A0.5000.85
531_Q537_W0.5000.85
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2wskA 1 0.9909 100 0.252 Contact Map
2vr5A 5 0.997 100 0.256 Contact Map
4j7rA 2 0.9802 100 0.261 Contact Map
1bf2A 1 0.9741 100 0.269 Contact Map
3wdhA 1 0.8721 100 0.317 Contact Map
2wanA 1 0.8767 100 0.322 Contact Map
2e8yA 1 0.8828 100 0.324 Contact Map
4j3vA 1 0.9148 100 0.348 Contact Map
2fhfA 1 0.9148 100 0.351 Contact Map
3k1dA 1 0.8356 100 0.362 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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