RECQ - ECOLI - GREMLIN Contacts

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RECQ - ATP-dependent DNA helicase RecQ

UniProt:	P15043	Sequences: MAQAEVLNLESGAKQVLQETFGYQQFRPGQEEIIDTVLSGRDCLVVMPTGGGKSLCYQIPALLLNGLTVVVSPLISLMKDQVDQLQANGVAAACLNSTQTREQQLEVMTGCRTGQIRLLYIAPERLMLDNFLEHLAHWNPVLLAVDEAHCISQWGHDFRPEYAALGQLRQRFPTLPFMALTATADDTTRQDIVRLLGLNDPLIQISSFDRPNIRYMLMEKFKPLDQLMRYVQEQRGKSGIIYCNSRAKVEDTAARLQSKGISAAAYHAGLENNVRADVQEKFQRDDLQIVVATVAFGMGINKPNVRFVVHFDIPRNIESYYQETGRAGRDGLPAEAMLFYDPADMAWLRRCLEEKPQGQLQDIERHKLNAMGAFAEAQTCRRLVLLNYFGEGRQEPCGNCDICLDPPKQYDGSTDAQIALSTIGRVNQRFGMGYVVEVIRGANNQRIRDYGHDKLKVYGMGRDKSHEHWVSVIRQLIHLGLVTQNIAQHSALQLTEAARPVLRGESSLQLAVPRIVALKPKAMQKSFGGNYDRKLFAKLRKLRKSIADESNVPPYVVFNDATLIEMAEQMPITASEMLSVNGVGMRKLERFGKPFMALIRAHVDGDDEE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10833
Length:	609 (516)
Sequences:	7127 (5156)
Seq/√Len:	227.0

ECOLI - RECQ DEAD RECG YFJK YEJH DBPA RHLE SRMB RAPA RHLB
BACSU - RECQ RECG YPRA CSHA RECS DBPA CSHB COMFA YWQA YFML
HALSA - HELS Q9HN80 Q9HNB2 RAD25 O52003 Q9HMW5
SULSO - Q981C8 Q97X74 HELS Q97YC4 Q97ZF9 HELX Q97Y93 Q97WW1 Q97WT0 Q97X64 Q980C0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
261_I	289_I	6.483	1.00
31_E	35_D	4.397	1.00
37_V	178_M	4.111	1.00
281_K	286_D	3.867	1.00
215_Y	324_T	3.668	1.00
18_Q	24_Q	3.533	1.00
277_D	281_K	3.519	1.00
423_I	482_V	3.423	1.00
544_K	548_D	3.302	1.00
414_T	418_I	3.217	1.00
243_C	249_V	3.138	1.00
552_V	556_V	3.039	1.00
414_T	417_Q	3.029	1.00
91_A	117_R	2.999	1.00
537_A	540_R	2.975	1.00
252_T	291_V	2.945	1.00
264_A	287_L	2.827	1.00
501_V	508_L	2.804	1.00
495_T	498_A	2.779	1.00
213_I	336_A	2.724	1.00
382_R	386_L	2.700	1.00
536_F	540_R	2.675	1.00
253_A	263_A	2.631	1.00
224_L	255_R	2.598	1.00
93_A	107_V	2.567	1.00
383_L	396_P	2.546	1.00
58_Q	85_L	2.539	1.00
542_L	546_I	2.506	1.00
227_L	309_V	2.478	1.00
228_M	259_K	2.421	1.00
231_V	261_I	2.416	1.00
100_T	103_Q	2.404	1.00
230_Y	337_M	2.397	1.00
419_A	473_I	2.384	1.00
270_L	274_V	2.370	1.00
243_C	252_T	2.366	1.00
434_Y	452_H	2.362	1.00
271_E	274_V	2.335	1.00
239_G	307_F	2.333	1.00
265_A	278_V	2.280	1.00
443_N	448_R	2.228	1.00
553_P	556_V	2.217	1.00
198_L	201_P	2.190	1.00
352_L	355_K	2.153	1.00
36_T	43_C	2.144	1.00
121_I	126_L	2.131	1.00
69_V	143_L	2.130	1.00
79_K	83_D	2.108	1.00
264_A	278_V	2.070	1.00
255_R	259_K	2.065	1.00
234_Q	237_K	2.055	1.00
262_S	288_Q	2.048	1.00
264_A	281_K	2.041	1.00
350_R	354_E	2.011	1.00
110_G	115_Q	1.996	1.00
136_A	171_R	1.980	1.00
33_I	45_V	1.977	1.00
85_L	118_L	1.958	1.00
116_I	119_L	1.943	1.00
494_L	498_A	1.941	1.00
250_E	265_A	1.933	1.00
500_P	506_S	1.927	1.00
461_G	469_W	1.920	1.00
278_V	290_V	1.919	1.00
16_V	59_I	1.906	1.00
546_I	550_S	1.879	1.00
465_S	468_H	1.846	1.00
456_K	460_M	1.845	1.00
213_I	216_M	1.841	1.00
276_A	280_E	1.820	1.00
445_Q	449_D	1.812	1.00
501_V	504_G	1.810	1.00
348_L	352_L	1.799	1.00
38_L	63_L	1.781	1.00
355_K	358_G	1.772	1.00
246_R	269_G	1.772	1.00
215_Y	218_M	1.758	1.00
227_L	311_F	1.746	1.00
383_L	387_N	1.742	1.00
112_R	137_H	1.741	1.00
351_C	354_E	1.715	1.00
231_V	307_F	1.698	1.00
386_L	390_G	1.689	1.00
452_H	455_L	1.680	1.00
212_N	215_Y	1.652	1.00
72_S	81_Q	1.641	1.00
442_A	445_Q	1.621	1.00
538_K	541_K	1.620	1.00
36_T	41_R	1.620	1.00
364_E	367_K	1.611	1.00
347_W	351_C	1.605	1.00
232_Q	259_K	1.575	1.00
217_L	374_F	1.574	1.00
464_K	468_H	1.546	1.00
351_C	358_G	1.539	1.00
351_C	355_K	1.536	1.00
400_C	403_C	1.531	1.00
503_R	507_S	1.514	1.00
496_E	499_R	1.512	1.00
436_V	440_R	1.509	1.00
348_L	351_C	1.509	1.00
85_L	120_Y	1.506	1.00
61_A	68_T	1.500	1.00
148_A	179_A	1.499	1.00
382_R	385_L	1.495	1.00
334_A	338_L	1.485	1.00
224_L	252_T	1.470	1.00
93_A	116_I	1.466	1.00
543_R	547_A	1.455	1.00
498_A	502_L	1.452	1.00
421_S	425_R	1.450	1.00
435_V	439_I	1.443	1.00
442_A	458_Y	1.442	1.00
451_G	454_K	1.439	1.00
385_L	389_F	1.433	1.00
436_V	439_I	1.425	1.00
458_Y	461_G	1.422	1.00
102_E	105_L	1.415	1.00
324_T	336_A	1.399	1.00
247_A	251_D	1.383	1.00
222_K	225_D	1.381	1.00
185_D	188_T	1.375	1.00
497_A	506_S	1.369	1.00
476_L	480_G	1.367	1.00
413_S	416_A	1.367	1.00
29_G	45_V	1.364	1.00
316_N	319_S	1.353	1.00
352_L	356_P	1.350	1.00
505_E	509_Q	1.346	1.00
354_E	357_Q	1.341	1.00
487_A	490_S	1.320	1.00
41_R	202_L	1.314	1.00
386_L	389_F	1.313	1.00
296_F	300_I	1.311	1.00
388_Y	391_E	1.309	1.00
347_W	350_R	1.305	1.00
349_R	352_L	1.303	1.00
214_R	217_L	1.295	1.00
69_V	140_P	1.295	1.00
280_E	284_R	1.291	1.00
493_Q	496_E	1.281	1.00
127_M	161_E	1.281	1.00
213_I	217_L	1.277	1.00
532_D	535_L	1.270	1.00
535_L	539_L	1.265	1.00
457_V	460_M	1.253	1.00
544_K	554_P	1.247	1.00
538_K	542_L	1.246	1.00
209_D	382_R	1.242	1.00
536_F	539_L	1.234	1.00
160_P	164_A	1.231	1.00
65_N	139_N	1.231	1.00
248_K	312_D	1.216	1.00
36_T	202_L	1.216	1.00
223_P	312_D	1.203	1.00
190_Q	194_R	1.203	1.00
264_A	290_V	1.199	1.00
111_C	119_L	1.195	1.00
274_V	278_V	1.192	1.00
207_S	391_E	1.189	1.00
542_L	545_S	1.184	1.00
426_V	438_V	1.184	1.00
34_I	59_I	1.183	1.00
243_C	291_V	1.181	1.00
372_G	376_E	1.180	1.00
540_R	545_S	1.179	1.00
369_N	373_A	1.175	1.00
363_I	367_K	1.172	1.00
500_P	504_G	1.167	1.00
348_L	355_K	1.167	1.00
546_I	549_E	1.166	1.00
214_R	218_M	1.166	1.00
209_D	217_L	1.166	1.00
410_Y	415_D	1.160	1.00
228_M	255_R	1.159	1.00
535_L	538_K	1.159	1.00
450_Y	453_D	1.153	1.00
443_N	453_D	1.152	1.00
101_R	105_L	1.151	1.00
475_Q	478_H	1.150	1.00
380_C	390_G	1.146	1.00
64_L	142_L	1.145	1.00
495_T	503_R	1.144	1.00
162_Y	165_L	1.143	1.00
501_V	505_E	1.142	1.00
256_L	291_V	1.133	1.00
189_R	205_I	1.133	1.00
108_M	112_R	1.132	1.00
413_S	420_L	1.131	1.00
334_A	341_D	1.131	1.00
500_P	505_E	1.130	1.00
459_G	462_R	1.130	1.00
461_G	464_K	1.126	1.00
534_K	538_K	1.121	1.00
248_K	251_D	1.121	1.00
231_V	241_I	1.117	1.00
400_C	404_L	1.116	1.00
502_L	508_L	1.114	1.00
486_I	489_H	1.112	1.00
462_R	466_H	1.112	1.00
382_R	389_F	1.111	1.00
547_A	554_P	1.110	1.00
224_L	259_K	1.110	1.00
497_A	501_V	1.108	1.00
535_L	546_I	1.105	1.00
94_C	98_T	1.102	1.00
418_I	421_S	1.099	1.00
531_Y	535_L	1.099	1.00
348_L	358_G	1.092	1.00
545_S	549_E	1.091	1.00
545_S	548_D	1.088	1.00
193_V	203_I	1.085	1.00
257_Q	263_A	1.084	1.00
67_L	117_R	1.081	1.00
361_Q	364_E	1.079	1.00
381_R	390_G	1.073	1.00
252_T	311_F	1.073	1.00
507_S	510_L	1.073	1.00
461_G	465_S	1.069	1.00
490_S	498_A	1.067	1.00
447_I	453_D	1.066	1.00
470_V	474_R	1.066	1.00
496_E	500_P	1.062	1.00
498_A	501_V	1.060	1.00
552_V	555_Y	1.057	1.00
385_L	390_G	1.051	1.00
504_G	508_L	1.051	1.00
500_P	503_R	1.051	1.00
236_G	288_Q	1.048	1.00
309_V	337_M	1.048	1.00
409_Q	412_G	1.045	1.00
382_R	390_G	1.038	1.00
537_A	545_S	1.036	1.00
474_R	478_H	1.035	1.00
430_F	452_H	1.035	1.00
485_N	489_H	1.033	1.00
225_D	229_R	1.032	1.00
438_V	441_G	1.030	1.00
379_T	389_F	1.028	1.00
71_V	121_I	1.025	1.00
61_A	118_L	1.024	1.00
132_L	171_R	1.020	1.00
334_A	340_Y	1.020	1.00
79_K	280_E	1.016	1.00
541_K	548_D	1.011	1.00
170_Q	197_G	1.008	1.00
16_V	20_T	1.008	1.00
439_I	442_A	1.006	1.00
474_R	479_L	1.003	1.00
465_S	470_V	1.003	1.00
71_V	126_L	1.001	1.00
163_A	195_L	1.001	1.00
249_V	265_A	0.999	1.00
545_S	553_P	0.999	1.00
82_V	92_A	0.997	1.00
385_L	388_Y	0.989	1.00
45_V	180_L	0.987	1.00
417_Q	425_R	0.981	1.00
422_T	426_V	0.981	1.00
20_T	90_V	0.980	1.00
106_E	110_G	0.978	1.00
539_L	546_I	0.976	1.00
432_M	474_R	0.975	1.00
220_K	223_P	0.975	1.00
416_A	423_I	0.975	1.00
491_A	495_T	0.972	1.00
350_R	357_Q	0.971	1.00
253_A	265_A	0.971	1.00
136_A	172_F	0.969	1.00
498_A	508_L	0.967	1.00
278_V	287_L	0.965	1.00
481_L	484_Q	0.965	1.00
481_L	485_N	0.963	1.00
430_F	434_Y	0.955	1.00
495_T	504_G	0.955	1.00
476_L	482_V	0.950	1.00
346_A	349_R	0.950	1.00
416_A	420_L	0.948	1.00
434_Y	438_V	0.946	1.00
35_D	39_S	0.945	1.00
16_V	63_L	0.944	1.00
366_H	370_A	0.942	1.00
505_E	508_L	0.941	1.00
502_L	505_E	0.940	1.00
420_L	423_I	0.938	1.00
37_V	43_C	0.935	1.00
349_R	353_E	0.934	1.00
407_P	411_D	0.934	1.00
379_T	387_N	0.931	1.00
537_A	547_A	0.930	1.00
492_L	499_R	0.930	1.00
421_S	424_G	0.929	1.00
411_D	414_T	0.928	1.00
540_R	543_R	0.927	1.00
541_K	544_K	0.927	1.00
381_R	385_L	0.927	1.00
241_I	309_V	0.926	1.00
535_L	540_R	0.925	1.00
415_D	418_I	0.920	1.00
149_H	298_M	0.919	1.00
477_I	482_V	0.917	1.00
419_A	426_V	0.916	1.00
533_R	538_K	0.916	1.00
245_S	268_A	0.914	1.00
386_L	391_E	0.910	0.99
413_S	417_Q	0.909	0.99
218_M	226_Q	0.908	0.99
418_I	423_I	0.908	0.99
532_D	547_A	0.908	0.99
539_L	547_A	0.907	0.99
347_W	355_K	0.907	0.99
406_P	409_Q	0.907	0.99
355_K	360_L	0.904	0.99
399_N	404_L	0.900	0.99
466_H	470_V	0.899	0.99
374_F	378_Q	0.896	0.99
84_Q	301_N	0.895	0.99
488_Q	491_A	0.894	0.99
491_A	494_L	0.893	0.99
493_Q	498_A	0.892	0.99
425_R	457_V	0.892	0.99
477_I	484_Q	0.887	0.99
241_I	289_I	0.887	0.99
121_I	131_F	0.887	0.99
447_I	452_H	0.883	0.99
499_R	505_E	0.880	0.99
186_D	189_R	0.880	0.99
44_L	192_I	0.879	0.99
446_R	449_D	0.877	0.99
492_L	505_E	0.873	0.99
468_H	472_V	0.873	0.99
245_S	248_K	0.872	0.99
254_A	257_Q	0.872	0.99
434_Y	450_Y	0.872	0.99
551_N	556_V	0.872	0.99
497_A	500_P	0.871	0.99
543_R	546_I	0.870	0.99
367_K	372_G	0.868	0.99
220_K	312_D	0.868	0.99
539_L	542_L	0.865	0.99
371_M	375_A	0.861	0.99
381_R	384_V	0.860	0.99
158_F	161_E	0.857	0.99
384_V	390_G	0.854	0.99
407_P	412_G	0.854	0.99
478_H	481_L	0.853	0.99
159_R	162_Y	0.852	0.99
476_L	479_L	0.845	0.99
435_V	441_G	0.845	0.99
415_D	419_A	0.843	0.99
469_W	476_L	0.842	0.99
482_V	485_N	0.840	0.99
42_D	198_L	0.840	0.99
382_R	388_Y	0.839	0.99
477_I	480_G	0.838	0.99
380_C	384_V	0.837	0.99
381_R	388_Y	0.837	0.99
471_S	474_R	0.835	0.99
533_R	537_A	0.834	0.99
94_C	99_Q	0.834	0.99
161_E	164_A	0.833	0.99
547_A	553_P	0.833	0.99
491_A	503_R	0.833	0.99
534_K	545_S	0.831	0.99
486_I	490_S	0.830	0.99
470_V	477_I	0.830	0.99
472_V	479_L	0.829	0.99
430_F	450_Y	0.829	0.99
432_M	438_V	0.827	0.99
475_Q	480_G	0.827	0.99
381_R	386_L	0.824	0.99
93_A	119_L	0.824	0.99
159_R	163_A	0.824	0.99
439_I	443_N	0.823	0.99
464_K	467_E	0.823	0.99
42_D	169_R	0.823	0.99
37_V	180_L	0.822	0.99
254_A	258_S	0.822	0.99
67_L	119_L	0.819	0.99
411_D	420_L	0.818	0.99
435_V	438_V	0.818	0.99
266_Y	296_F	0.817	0.99
499_R	503_R	0.817	0.99
418_I	424_G	0.817	0.99
219_E	222_K	0.815	0.99
419_A	423_I	0.815	0.99
367_K	370_A	0.815	0.99
503_R	506_S	0.814	0.99
169_R	177_F	0.812	0.99
130_N	135_L	0.811	0.99
533_R	541_K	0.810	0.99
249_V	291_V	0.810	0.99
412_G	416_A	0.807	0.99
275_R	279_Q	0.804	0.99
432_M	436_V	0.801	0.99
531_Y	538_K	0.800	0.99
495_T	508_L	0.799	0.99
399_N	403_C	0.798	0.99
419_A	425_R	0.795	0.99
372_G	375_A	0.794	0.99
530_N	534_K	0.794	0.99
417_Q	420_L	0.791	0.99
537_A	543_R	0.791	0.99
495_T	502_L	0.791	0.99
532_D	537_A	0.789	0.99
469_W	473_I	0.789	0.99
420_L	424_G	0.788	0.99
347_W	352_L	0.787	0.99
497_A	508_L	0.786	0.98
504_G	510_L	0.783	0.98
29_G	33_I	0.781	0.98
548_D	551_N	0.779	0.98
409_Q	413_S	0.777	0.98
458_Y	464_K	0.776	0.98
502_L	510_L	0.772	0.98
56_C	60_P	0.771	0.98
371_M	374_F	0.770	0.98
433_G	436_V	0.768	0.98
467_E	470_V	0.768	0.98
491_A	496_E	0.767	0.98
41_R	200_D	0.764	0.98
189_R	193_V	0.762	0.98
275_R	282_F	0.760	0.98
463_D	468_H	0.760	0.98
127_M	164_A	0.759	0.98
142_L	178_M	0.758	0.98
374_F	380_C	0.758	0.98
57_Y	81_Q	0.756	0.98
373_A	378_Q	0.755	0.98
543_R	554_P	0.754	0.98
530_N	538_K	0.752	0.98
540_R	547_A	0.749	0.98
440_R	469_W	0.749	0.98
547_A	555_Y	0.747	0.98
367_K	373_A	0.745	0.98
79_K	276_A	0.744	0.98
477_I	485_N	0.743	0.98
506_S	509_Q	0.743	0.98
132_L	135_L	0.743	0.98
29_G	32_E	0.740	0.98
535_L	552_V	0.739	0.98
537_A	548_D	0.739	0.98
416_A	422_T	0.739	0.98
431_G	435_V	0.738	0.98
85_L	92_A	0.738	0.98
474_R	477_I	0.736	0.98
460_M	464_K	0.736	0.98
446_R	450_Y	0.736	0.98
104_Q	125_R	0.734	0.98
411_D	416_A	0.731	0.98
407_P	410_Y	0.731	0.98
30_Q	33_I	0.730	0.98
367_K	375_A	0.729	0.98
540_R	549_E	0.728	0.98
184_A	328_G	0.728	0.98
540_R	548_D	0.728	0.98
542_L	547_A	0.726	0.97
534_K	541_K	0.725	0.97
229_R	233_E	0.724	0.97
472_V	475_Q	0.723	0.97
104_Q	108_M	0.723	0.97
550_S	555_Y	0.722	0.97
158_F	162_Y	0.722	0.97
352_L	357_Q	0.720	0.97
449_D	453_D	0.720	0.97
484_Q	487_A	0.720	0.97
540_R	555_Y	0.719	0.97
473_I	477_I	0.718	0.97
536_F	541_K	0.717	0.97
444_N	448_R	0.714	0.97
469_W	475_Q	0.713	0.97
498_A	504_G	0.712	0.97
546_I	555_Y	0.708	0.97
382_R	391_E	0.707	0.97
444_N	447_I	0.707	0.97
33_I	204_Q	0.706	0.97
376_E	381_R	0.704	0.97
74_L	298_M	0.703	0.97
409_Q	416_A	0.703	0.97
458_Y	465_S	0.703	0.97
379_T	386_L	0.702	0.97
455_L	460_M	0.702	0.97
310_H	338_L	0.700	0.97
546_I	552_V	0.699	0.97
406_P	419_A	0.699	0.97
380_C	389_F	0.698	0.97
422_T	425_R	0.697	0.97
103_Q	107_V	0.696	0.97
387_N	390_G	0.695	0.97
430_F	435_V	0.694	0.97
104_Q	107_V	0.693	0.97
502_L	506_S	0.693	0.97
457_V	461_G	0.689	0.97
531_Y	537_A	0.688	0.97
542_L	550_S	0.688	0.97
476_L	481_L	0.688	0.97
461_G	466_H	0.686	0.96
496_E	501_V	0.685	0.96
406_P	411_D	0.684	0.96
438_V	447_I	0.683	0.96
431_G	434_Y	0.683	0.96
502_L	509_Q	0.683	0.96
490_S	501_V	0.681	0.96
499_R	506_S	0.681	0.96
223_P	339_F	0.681	0.96
473_I	476_L	0.680	0.96
469_W	477_I	0.680	0.96
240_I	292_A	0.680	0.96
485_N	488_Q	0.680	0.96
193_V	198_L	0.679	0.96
230_Y	307_F	0.678	0.96
494_L	500_P	0.675	0.96
397_C	400_C	0.674	0.96
536_F	549_E	0.673	0.96
539_L	543_R	0.672	0.96
536_F	547_A	0.671	0.96
74_L	124_E	0.671	0.96
142_L	180_L	0.669	0.96
438_V	452_H	0.668	0.96
406_P	412_G	0.668	0.96
371_M	380_C	0.667	0.96
223_P	226_Q	0.666	0.96
385_L	391_E	0.666	0.96
406_P	410_Y	0.664	0.96
541_K	545_S	0.664	0.96
442_A	448_R	0.663	0.96
382_R	387_N	0.663	0.96
422_T	457_V	0.663	0.96
538_K	545_S	0.663	0.96
485_N	493_Q	0.663	0.96
439_I	448_R	0.662	0.96
224_L	228_M	0.661	0.96
371_M	378_Q	0.661	0.96
484_Q	488_Q	0.659	0.96
532_D	539_L	0.659	0.96
253_A	257_Q	0.658	0.96
232_Q	261_I	0.658	0.96
535_L	543_R	0.655	0.95
545_S	550_S	0.653	0.95
440_R	443_N	0.652	0.95
548_D	553_P	0.651	0.95
381_R	391_E	0.651	0.95
454_K	458_Y	0.650	0.95
539_L	549_E	0.650	0.95
377_A	384_V	0.648	0.95
273_N	277_D	0.648	0.95
387_N	392_G	0.647	0.95
218_M	339_F	0.647	0.95
416_A	476_L	0.647	0.95
437_E	444_N	0.645	0.95
505_E	510_L	0.645	0.95
481_L	487_A	0.645	0.95
501_V	510_L	0.644	0.95
437_E	442_A	0.643	0.95
231_V	239_G	0.643	0.95
482_V	486_I	0.642	0.95
498_A	506_S	0.642	0.95
367_K	371_M	0.640	0.95
541_K	553_P	0.640	0.95
411_D	421_S	0.638	0.95
17_L	55_L	0.638	0.95
459_G	464_K	0.638	0.95
534_K	537_A	0.638	0.95
458_Y	462_R	0.637	0.95
408_K	411_D	0.634	0.95
210_R	213_I	0.633	0.94
381_R	401_D	0.633	0.94
188_T	191_D	0.632	0.94
546_I	554_P	0.631	0.94
495_T	501_V	0.630	0.94
531_Y	534_K	0.629	0.94
238_S	306_R	0.628	0.94
549_E	553_P	0.627	0.94
429_R	434_Y	0.624	0.94
542_L	549_E	0.624	0.94
367_K	376_E	0.624	0.94
86_Q	93_A	0.621	0.94
542_L	555_Y	0.621	0.94
439_I	446_R	0.620	0.94
373_A	376_E	0.619	0.94
411_D	422_T	0.619	0.94
405_D	411_D	0.618	0.94
540_R	544_K	0.618	0.94
430_F	436_V	0.618	0.94
131_F	135_L	0.618	0.94
544_K	547_A	0.617	0.94
368_L	375_A	0.617	0.94
67_L	141_V	0.616	0.94
493_Q	501_V	0.616	0.94
384_V	389_F	0.615	0.94
383_L	389_F	0.615	0.94
483_T	495_T	0.614	0.94
457_V	464_K	0.614	0.94
472_V	481_L	0.612	0.93
141_V	175_L	0.611	0.93
541_K	549_E	0.609	0.93
460_M	465_S	0.609	0.93
415_D	425_R	0.608	0.93
149_H	322_Q	0.607	0.93
417_Q	422_T	0.607	0.93
351_C	359_Q	0.606	0.93
191_D	195_L	0.605	0.93
365_R	374_F	0.605	0.93
327_A	334_A	0.605	0.93
499_R	502_L	0.604	0.93
439_I	461_G	0.604	0.93
533_R	539_L	0.604	0.93
199_N	202_L	0.602	0.93
430_F	438_V	0.602	0.93
422_T	427_N	0.602	0.93
459_G	463_D	0.602	0.93
471_S	477_I	0.601	0.93
396_P	399_N	0.600	0.93
462_R	465_S	0.600	0.93
317_I	374_F	0.598	0.93
434_Y	446_R	0.597	0.93
470_V	487_A	0.597	0.93
87_A	550_S	0.597	0.93
482_V	487_A	0.596	0.93
285_D	288_Q	0.594	0.92
249_V	253_A	0.594	0.92
457_V	465_S	0.594	0.92
494_L	501_V	0.594	0.92
441_G	444_N	0.593	0.92
536_F	543_R	0.592	0.92
536_F	544_K	0.591	0.92
416_A	426_V	0.590	0.92
538_K	547_A	0.589	0.92
443_N	447_I	0.589	0.92
436_V	444_N	0.589	0.92
490_S	510_L	0.588	0.92
152_S	191_D	0.588	0.92
470_V	489_H	0.588	0.92
448_R	453_D	0.588	0.92
532_D	540_R	0.586	0.92
529_G	533_R	0.586	0.92
495_T	499_R	0.585	0.92
472_V	480_G	0.584	0.92
352_L	358_G	0.583	0.92
497_A	502_L	0.582	0.92
539_L	555_Y	0.582	0.92
379_T	383_L	0.579	0.91
501_V	507_S	0.579	0.91
155_G	158_F	0.579	0.91
57_Y	180_L	0.578	0.91
533_R	552_V	0.575	0.91
406_P	413_S	0.574	0.91
192_I	195_L	0.574	0.91
411_D	417_Q	0.573	0.91
371_M	376_E	0.571	0.91
537_A	541_K	0.570	0.91
539_L	553_P	0.570	0.91
544_K	549_E	0.569	0.91
230_Y	339_F	0.568	0.91
379_T	384_V	0.567	0.91
434_Y	439_I	0.567	0.91
265_A	274_V	0.566	0.91
224_L	251_D	0.566	0.91
23_Y	55_L	0.565	0.90
535_L	542_L	0.565	0.90
547_A	552_V	0.564	0.90
368_L	376_E	0.563	0.90
212_N	218_M	0.563	0.90
74_L	149_H	0.561	0.90
207_S	210_R	0.561	0.90
419_A	422_T	0.561	0.90
499_R	504_G	0.560	0.90
429_R	436_V	0.560	0.90
423_I	426_V	0.559	0.90
500_P	508_L	0.558	0.90
408_K	418_I	0.558	0.90
442_A	447_I	0.558	0.90
492_L	503_R	0.556	0.90
547_A	550_S	0.556	0.90
398_G	401_D	0.556	0.90
548_D	555_Y	0.556	0.90
432_M	435_V	0.555	0.90
425_R	428_Q	0.555	0.90
492_L	502_L	0.555	0.90
338_L	341_D	0.555	0.90
306_R	332_L	0.554	0.90
224_L	311_F	0.554	0.90
425_R	460_M	0.553	0.89
408_K	416_A	0.553	0.89
347_W	356_P	0.551	0.89
531_Y	549_E	0.551	0.89
414_T	423_I	0.550	0.89
472_V	478_H	0.549	0.89
110_G	116_I	0.549	0.89
539_L	544_K	0.548	0.89
446_R	452_H	0.545	0.89
496_E	505_E	0.545	0.89
83_D	280_E	0.545	0.89
465_S	469_W	0.545	0.89
220_K	226_Q	0.545	0.89
448_R	458_Y	0.544	0.89
380_C	388_Y	0.543	0.89
380_C	386_L	0.542	0.89
440_R	445_Q	0.542	0.89
541_K	547_A	0.542	0.89
480_G	483_T	0.541	0.88
470_V	486_I	0.541	0.88
418_I	425_R	0.540	0.88
468_H	471_S	0.540	0.88
447_I	458_Y	0.539	0.88
471_S	475_Q	0.538	0.88
372_G	378_Q	0.538	0.88
539_L	554_P	0.537	0.88
76_S	124_E	0.537	0.88
348_L	356_P	0.536	0.88
533_R	544_K	0.536	0.88
413_S	419_A	0.535	0.88
547_A	556_V	0.534	0.88
438_V	442_A	0.534	0.88
480_G	485_N	0.533	0.88
546_I	553_P	0.533	0.88
491_A	498_A	0.531	0.88
469_W	474_R	0.530	0.87
405_D	410_Y	0.529	0.87
363_I	374_F	0.529	0.87
95_L	131_F	0.529	0.87
65_N	117_R	0.529	0.87
474_R	484_Q	0.527	0.87
418_I	463_D	0.526	0.87
369_N	376_E	0.524	0.87
431_G	436_V	0.524	0.87
432_M	473_I	0.524	0.87
326_R	329_R	0.524	0.87
541_K	551_N	0.523	0.87
28_P	32_E	0.523	0.87
471_S	485_N	0.522	0.87
160_P	163_A	0.522	0.87
349_R	355_K	0.521	0.87
417_Q	421_S	0.521	0.87
50_G	53_K	0.520	0.86
410_Y	414_T	0.520	0.86
399_N	402_I	0.520	0.86
375_A	378_Q	0.520	0.86
464_K	471_S	0.519	0.86
350_R	355_K	0.518	0.86
475_Q	481_L	0.518	0.86
432_M	437_E	0.517	0.86
454_K	457_V	0.516	0.86
414_T	422_T	0.516	0.86
539_L	551_N	0.516	0.86
424_G	427_N	0.516	0.86
251_D	255_R	0.516	0.86
535_L	544_K	0.515	0.86
481_L	501_V	0.515	0.86
193_V	199_N	0.514	0.86
414_T	428_Q	0.514	0.86
143_L	169_R	0.513	0.86
420_L	428_Q	0.512	0.86
542_L	553_P	0.512	0.86
270_L	278_V	0.511	0.85
64_L	68_T	0.511	0.85
418_I	460_M	0.509	0.85
396_P	400_C	0.509	0.85
540_R	551_N	0.508	0.85
470_V	480_G	0.508	0.85
442_A	446_R	0.507	0.85
534_K	546_I	0.507	0.85
407_P	413_S	0.506	0.85
478_H	482_V	0.506	0.85
347_W	358_G	0.506	0.85
538_K	543_R	0.505	0.85
538_K	544_K	0.505	0.85
363_I	378_Q	0.505	0.85
537_A	542_L	0.504	0.85
550_S	556_V	0.503	0.85
497_A	504_G	0.503	0.85
99_Q	107_V	0.502	0.84
414_T	425_R	0.500	0.84
490_S	499_R	0.500	0.84

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1oywA	1	0.8473	100	0.262	Contact Map
4q48A	1	0.8194	100	0.282	Contact Map
4o3mA	1	0.9557	100	0.283	Contact Map
2v1xA	1	0.8194	100	0.318	Contact Map
4pxaA	1	0.5977	100	0.386	Contact Map
4nhoA	1	0.5846	100	0.392	Contact Map
4ljyA	1	0.6076	100	0.395	Contact Map
2db3A	1	0.5895	100	0.395	Contact Map
4d25A	1	0.5862	100	0.409	Contact Map
4w7sA	2	0.6174	100	0.411	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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