GREMLIN Database
RECQ - ATP-dependent DNA helicase RecQ
UniProt: P15043 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10833
Length: 609 (516)
Sequences: 7127 (5156)
Seq/√Len: 227.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
261_I289_I6.4831.00
31_E35_D4.3971.00
37_V178_M4.1111.00
281_K286_D3.8671.00
215_Y324_T3.6681.00
18_Q24_Q3.5331.00
277_D281_K3.5191.00
423_I482_V3.4231.00
544_K548_D3.3021.00
414_T418_I3.2171.00
243_C249_V3.1381.00
552_V556_V3.0391.00
414_T417_Q3.0291.00
91_A117_R2.9991.00
537_A540_R2.9751.00
252_T291_V2.9451.00
264_A287_L2.8271.00
501_V508_L2.8041.00
495_T498_A2.7791.00
213_I336_A2.7241.00
382_R386_L2.7001.00
536_F540_R2.6751.00
253_A263_A2.6311.00
224_L255_R2.5981.00
93_A107_V2.5671.00
383_L396_P2.5461.00
58_Q85_L2.5391.00
542_L546_I2.5061.00
227_L309_V2.4781.00
228_M259_K2.4211.00
231_V261_I2.4161.00
100_T103_Q2.4041.00
230_Y337_M2.3971.00
419_A473_I2.3841.00
270_L274_V2.3701.00
243_C252_T2.3661.00
434_Y452_H2.3621.00
271_E274_V2.3351.00
239_G307_F2.3331.00
265_A278_V2.2801.00
443_N448_R2.2281.00
553_P556_V2.2171.00
198_L201_P2.1901.00
352_L355_K2.1531.00
36_T43_C2.1441.00
121_I126_L2.1311.00
69_V143_L2.1301.00
79_K83_D2.1081.00
264_A278_V2.0701.00
255_R259_K2.0651.00
234_Q237_K2.0551.00
262_S288_Q2.0481.00
264_A281_K2.0411.00
350_R354_E2.0111.00
110_G115_Q1.9961.00
136_A171_R1.9801.00
33_I45_V1.9771.00
85_L118_L1.9581.00
116_I119_L1.9431.00
494_L498_A1.9411.00
250_E265_A1.9331.00
500_P506_S1.9271.00
461_G469_W1.9201.00
278_V290_V1.9191.00
16_V59_I1.9061.00
546_I550_S1.8791.00
465_S468_H1.8461.00
456_K460_M1.8451.00
213_I216_M1.8411.00
276_A280_E1.8201.00
445_Q449_D1.8121.00
501_V504_G1.8101.00
348_L352_L1.7991.00
38_L63_L1.7811.00
355_K358_G1.7721.00
246_R269_G1.7721.00
215_Y218_M1.7581.00
227_L311_F1.7461.00
383_L387_N1.7421.00
112_R137_H1.7411.00
351_C354_E1.7151.00
231_V307_F1.6981.00
386_L390_G1.6891.00
452_H455_L1.6801.00
212_N215_Y1.6521.00
72_S81_Q1.6411.00
442_A445_Q1.6211.00
538_K541_K1.6201.00
36_T41_R1.6201.00
364_E367_K1.6111.00
347_W351_C1.6051.00
232_Q259_K1.5751.00
217_L374_F1.5741.00
464_K468_H1.5461.00
351_C358_G1.5391.00
351_C355_K1.5361.00
400_C403_C1.5311.00
503_R507_S1.5141.00
496_E499_R1.5121.00
436_V440_R1.5091.00
348_L351_C1.5091.00
85_L120_Y1.5061.00
61_A68_T1.5001.00
148_A179_A1.4991.00
382_R385_L1.4951.00
334_A338_L1.4851.00
224_L252_T1.4701.00
93_A116_I1.4661.00
543_R547_A1.4551.00
498_A502_L1.4521.00
421_S425_R1.4501.00
435_V439_I1.4431.00
442_A458_Y1.4421.00
451_G454_K1.4391.00
385_L389_F1.4331.00
436_V439_I1.4251.00
458_Y461_G1.4221.00
102_E105_L1.4151.00
324_T336_A1.3991.00
247_A251_D1.3831.00
222_K225_D1.3811.00
185_D188_T1.3751.00
497_A506_S1.3691.00
476_L480_G1.3671.00
413_S416_A1.3671.00
29_G45_V1.3641.00
316_N319_S1.3531.00
352_L356_P1.3501.00
505_E509_Q1.3461.00
354_E357_Q1.3411.00
487_A490_S1.3201.00
41_R202_L1.3141.00
386_L389_F1.3131.00
296_F300_I1.3111.00
388_Y391_E1.3091.00
347_W350_R1.3051.00
349_R352_L1.3031.00
214_R217_L1.2951.00
69_V140_P1.2951.00
280_E284_R1.2911.00
493_Q496_E1.2811.00
127_M161_E1.2811.00
213_I217_L1.2771.00
532_D535_L1.2701.00
535_L539_L1.2651.00
457_V460_M1.2531.00
544_K554_P1.2471.00
538_K542_L1.2461.00
209_D382_R1.2421.00
536_F539_L1.2341.00
160_P164_A1.2311.00
65_N139_N1.2311.00
248_K312_D1.2161.00
36_T202_L1.2161.00
223_P312_D1.2031.00
190_Q194_R1.2031.00
264_A290_V1.1991.00
111_C119_L1.1951.00
274_V278_V1.1921.00
207_S391_E1.1891.00
542_L545_S1.1841.00
426_V438_V1.1841.00
34_I59_I1.1831.00
243_C291_V1.1811.00
372_G376_E1.1801.00
540_R545_S1.1791.00
369_N373_A1.1751.00
363_I367_K1.1721.00
500_P504_G1.1671.00
348_L355_K1.1671.00
546_I549_E1.1661.00
214_R218_M1.1661.00
209_D217_L1.1661.00
410_Y415_D1.1601.00
228_M255_R1.1591.00
535_L538_K1.1591.00
450_Y453_D1.1531.00
443_N453_D1.1521.00
101_R105_L1.1511.00
475_Q478_H1.1501.00
380_C390_G1.1461.00
64_L142_L1.1451.00
495_T503_R1.1441.00
162_Y165_L1.1431.00
501_V505_E1.1421.00
256_L291_V1.1331.00
189_R205_I1.1331.00
108_M112_R1.1321.00
413_S420_L1.1311.00
334_A341_D1.1311.00
500_P505_E1.1301.00
459_G462_R1.1301.00
461_G464_K1.1261.00
534_K538_K1.1211.00
248_K251_D1.1211.00
231_V241_I1.1171.00
400_C404_L1.1161.00
502_L508_L1.1141.00
486_I489_H1.1121.00
462_R466_H1.1121.00
382_R389_F1.1111.00
547_A554_P1.1101.00
224_L259_K1.1101.00
497_A501_V1.1081.00
535_L546_I1.1051.00
94_C98_T1.1021.00
418_I421_S1.0991.00
531_Y535_L1.0991.00
348_L358_G1.0921.00
545_S549_E1.0911.00
545_S548_D1.0881.00
193_V203_I1.0851.00
257_Q263_A1.0841.00
67_L117_R1.0811.00
361_Q364_E1.0791.00
381_R390_G1.0731.00
252_T311_F1.0731.00
507_S510_L1.0731.00
461_G465_S1.0691.00
490_S498_A1.0671.00
447_I453_D1.0661.00
470_V474_R1.0661.00
496_E500_P1.0621.00
498_A501_V1.0601.00
552_V555_Y1.0571.00
385_L390_G1.0511.00
504_G508_L1.0511.00
500_P503_R1.0511.00
236_G288_Q1.0481.00
309_V337_M1.0481.00
409_Q412_G1.0451.00
382_R390_G1.0381.00
537_A545_S1.0361.00
474_R478_H1.0351.00
430_F452_H1.0351.00
485_N489_H1.0331.00
225_D229_R1.0321.00
438_V441_G1.0301.00
379_T389_F1.0281.00
71_V121_I1.0251.00
61_A118_L1.0241.00
132_L171_R1.0201.00
334_A340_Y1.0201.00
79_K280_E1.0161.00
541_K548_D1.0111.00
170_Q197_G1.0081.00
16_V20_T1.0081.00
439_I442_A1.0061.00
474_R479_L1.0031.00
465_S470_V1.0031.00
71_V126_L1.0011.00
163_A195_L1.0011.00
249_V265_A0.9991.00
545_S553_P0.9991.00
82_V92_A0.9971.00
385_L388_Y0.9891.00
45_V180_L0.9871.00
417_Q425_R0.9811.00
422_T426_V0.9811.00
20_T90_V0.9801.00
106_E110_G0.9781.00
539_L546_I0.9761.00
432_M474_R0.9751.00
220_K223_P0.9751.00
416_A423_I0.9751.00
491_A495_T0.9721.00
350_R357_Q0.9711.00
253_A265_A0.9711.00
136_A172_F0.9691.00
498_A508_L0.9671.00
278_V287_L0.9651.00
481_L484_Q0.9651.00
481_L485_N0.9631.00
430_F434_Y0.9551.00
495_T504_G0.9551.00
476_L482_V0.9501.00
346_A349_R0.9501.00
416_A420_L0.9481.00
434_Y438_V0.9461.00
35_D39_S0.9451.00
16_V63_L0.9441.00
366_H370_A0.9421.00
505_E508_L0.9411.00
502_L505_E0.9401.00
420_L423_I0.9381.00
37_V43_C0.9351.00
349_R353_E0.9341.00
407_P411_D0.9341.00
379_T387_N0.9311.00
537_A547_A0.9301.00
492_L499_R0.9301.00
421_S424_G0.9291.00
411_D414_T0.9281.00
540_R543_R0.9271.00
541_K544_K0.9271.00
381_R385_L0.9271.00
241_I309_V0.9261.00
535_L540_R0.9251.00
415_D418_I0.9201.00
149_H298_M0.9191.00
477_I482_V0.9171.00
419_A426_V0.9161.00
533_R538_K0.9161.00
245_S268_A0.9141.00
386_L391_E0.9100.99
413_S417_Q0.9090.99
218_M226_Q0.9080.99
418_I423_I0.9080.99
532_D547_A0.9080.99
539_L547_A0.9070.99
347_W355_K0.9070.99
406_P409_Q0.9070.99
355_K360_L0.9040.99
399_N404_L0.9000.99
466_H470_V0.8990.99
374_F378_Q0.8960.99
84_Q301_N0.8950.99
488_Q491_A0.8940.99
491_A494_L0.8930.99
493_Q498_A0.8920.99
425_R457_V0.8920.99
477_I484_Q0.8870.99
241_I289_I0.8870.99
121_I131_F0.8870.99
447_I452_H0.8830.99
499_R505_E0.8800.99
186_D189_R0.8800.99
44_L192_I0.8790.99
446_R449_D0.8770.99
492_L505_E0.8730.99
468_H472_V0.8730.99
245_S248_K0.8720.99
254_A257_Q0.8720.99
434_Y450_Y0.8720.99
551_N556_V0.8720.99
497_A500_P0.8710.99
543_R546_I0.8700.99
367_K372_G0.8680.99
220_K312_D0.8680.99
539_L542_L0.8650.99
371_M375_A0.8610.99
381_R384_V0.8600.99
158_F161_E0.8570.99
384_V390_G0.8540.99
407_P412_G0.8540.99
478_H481_L0.8530.99
159_R162_Y0.8520.99
476_L479_L0.8450.99
435_V441_G0.8450.99
415_D419_A0.8430.99
469_W476_L0.8420.99
482_V485_N0.8400.99
42_D198_L0.8400.99
382_R388_Y0.8390.99
477_I480_G0.8380.99
380_C384_V0.8370.99
381_R388_Y0.8370.99
471_S474_R0.8350.99
533_R537_A0.8340.99
94_C99_Q0.8340.99
161_E164_A0.8330.99
547_A553_P0.8330.99
491_A503_R0.8330.99
534_K545_S0.8310.99
486_I490_S0.8300.99
470_V477_I0.8300.99
472_V479_L0.8290.99
430_F450_Y0.8290.99
432_M438_V0.8270.99
475_Q480_G0.8270.99
381_R386_L0.8240.99
93_A119_L0.8240.99
159_R163_A0.8240.99
439_I443_N0.8230.99
464_K467_E0.8230.99
42_D169_R0.8230.99
37_V180_L0.8220.99
254_A258_S0.8220.99
67_L119_L0.8190.99
411_D420_L0.8180.99
435_V438_V0.8180.99
266_Y296_F0.8170.99
499_R503_R0.8170.99
418_I424_G0.8170.99
219_E222_K0.8150.99
419_A423_I0.8150.99
367_K370_A0.8150.99
503_R506_S0.8140.99
169_R177_F0.8120.99
130_N135_L0.8110.99
533_R541_K0.8100.99
249_V291_V0.8100.99
412_G416_A0.8070.99
275_R279_Q0.8040.99
432_M436_V0.8010.99
531_Y538_K0.8000.99
495_T508_L0.7990.99
399_N403_C0.7980.99
419_A425_R0.7950.99
372_G375_A0.7940.99
530_N534_K0.7940.99
417_Q420_L0.7910.99
537_A543_R0.7910.99
495_T502_L0.7910.99
532_D537_A0.7890.99
469_W473_I0.7890.99
420_L424_G0.7880.99
347_W352_L0.7870.99
497_A508_L0.7860.98
504_G510_L0.7830.98
29_G33_I0.7810.98
548_D551_N0.7790.98
409_Q413_S0.7770.98
458_Y464_K0.7760.98
502_L510_L0.7720.98
56_C60_P0.7710.98
371_M374_F0.7700.98
433_G436_V0.7680.98
467_E470_V0.7680.98
491_A496_E0.7670.98
41_R200_D0.7640.98
189_R193_V0.7620.98
275_R282_F0.7600.98
463_D468_H0.7600.98
127_M164_A0.7590.98
142_L178_M0.7580.98
374_F380_C0.7580.98
57_Y81_Q0.7560.98
373_A378_Q0.7550.98
543_R554_P0.7540.98
530_N538_K0.7520.98
540_R547_A0.7490.98
440_R469_W0.7490.98
547_A555_Y0.7470.98
367_K373_A0.7450.98
79_K276_A0.7440.98
477_I485_N0.7430.98
506_S509_Q0.7430.98
132_L135_L0.7430.98
29_G32_E0.7400.98
535_L552_V0.7390.98
537_A548_D0.7390.98
416_A422_T0.7390.98
431_G435_V0.7380.98
85_L92_A0.7380.98
474_R477_I0.7360.98
460_M464_K0.7360.98
446_R450_Y0.7360.98
104_Q125_R0.7340.98
411_D416_A0.7310.98
407_P410_Y0.7310.98
30_Q33_I0.7300.98
367_K375_A0.7290.98
540_R549_E0.7280.98
184_A328_G0.7280.98
540_R548_D0.7280.98
542_L547_A0.7260.97
534_K541_K0.7250.97
229_R233_E0.7240.97
472_V475_Q0.7230.97
104_Q108_M0.7230.97
550_S555_Y0.7220.97
158_F162_Y0.7220.97
352_L357_Q0.7200.97
449_D453_D0.7200.97
484_Q487_A0.7200.97
540_R555_Y0.7190.97
473_I477_I0.7180.97
536_F541_K0.7170.97
444_N448_R0.7140.97
469_W475_Q0.7130.97
498_A504_G0.7120.97
546_I555_Y0.7080.97
382_R391_E0.7070.97
444_N447_I0.7070.97
33_I204_Q0.7060.97
376_E381_R0.7040.97
74_L298_M0.7030.97
409_Q416_A0.7030.97
458_Y465_S0.7030.97
379_T386_L0.7020.97
455_L460_M0.7020.97
310_H338_L0.7000.97
546_I552_V0.6990.97
406_P419_A0.6990.97
380_C389_F0.6980.97
422_T425_R0.6970.97
103_Q107_V0.6960.97
387_N390_G0.6950.97
430_F435_V0.6940.97
104_Q107_V0.6930.97
502_L506_S0.6930.97
457_V461_G0.6890.97
531_Y537_A0.6880.97
542_L550_S0.6880.97
476_L481_L0.6880.97
461_G466_H0.6860.96
496_E501_V0.6850.96
406_P411_D0.6840.96
438_V447_I0.6830.96
431_G434_Y0.6830.96
502_L509_Q0.6830.96
490_S501_V0.6810.96
499_R506_S0.6810.96
223_P339_F0.6810.96
473_I476_L0.6800.96
469_W477_I0.6800.96
240_I292_A0.6800.96
485_N488_Q0.6800.96
193_V198_L0.6790.96
230_Y307_F0.6780.96
494_L500_P0.6750.96
397_C400_C0.6740.96
536_F549_E0.6730.96
539_L543_R0.6720.96
536_F547_A0.6710.96
74_L124_E0.6710.96
142_L180_L0.6690.96
438_V452_H0.6680.96
406_P412_G0.6680.96
371_M380_C0.6670.96
223_P226_Q0.6660.96
385_L391_E0.6660.96
406_P410_Y0.6640.96
541_K545_S0.6640.96
442_A448_R0.6630.96
382_R387_N0.6630.96
422_T457_V0.6630.96
538_K545_S0.6630.96
485_N493_Q0.6630.96
439_I448_R0.6620.96
224_L228_M0.6610.96
371_M378_Q0.6610.96
484_Q488_Q0.6590.96
532_D539_L0.6590.96
253_A257_Q0.6580.96
232_Q261_I0.6580.96
535_L543_R0.6550.95
545_S550_S0.6530.95
440_R443_N0.6520.95
548_D553_P0.6510.95
381_R391_E0.6510.95
454_K458_Y0.6500.95
539_L549_E0.6500.95
377_A384_V0.6480.95
273_N277_D0.6480.95
387_N392_G0.6470.95
218_M339_F0.6470.95
416_A476_L0.6470.95
437_E444_N0.6450.95
505_E510_L0.6450.95
481_L487_A0.6450.95
501_V510_L0.6440.95
437_E442_A0.6430.95
231_V239_G0.6430.95
482_V486_I0.6420.95
498_A506_S0.6420.95
367_K371_M0.6400.95
541_K553_P0.6400.95
411_D421_S0.6380.95
17_L55_L0.6380.95
459_G464_K0.6380.95
534_K537_A0.6380.95
458_Y462_R0.6370.95
408_K411_D0.6340.95
210_R213_I0.6330.94
381_R401_D0.6330.94
188_T191_D0.6320.94
546_I554_P0.6310.94
495_T501_V0.6300.94
531_Y534_K0.6290.94
238_S306_R0.6280.94
549_E553_P0.6270.94
429_R434_Y0.6240.94
542_L549_E0.6240.94
367_K376_E0.6240.94
86_Q93_A0.6210.94
542_L555_Y0.6210.94
439_I446_R0.6200.94
373_A376_E0.6190.94
411_D422_T0.6190.94
405_D411_D0.6180.94
540_R544_K0.6180.94
430_F436_V0.6180.94
131_F135_L0.6180.94
544_K547_A0.6170.94
368_L375_A0.6170.94
67_L141_V0.6160.94
493_Q501_V0.6160.94
384_V389_F0.6150.94
383_L389_F0.6150.94
483_T495_T0.6140.94
457_V464_K0.6140.94
472_V481_L0.6120.93
141_V175_L0.6110.93
541_K549_E0.6090.93
460_M465_S0.6090.93
415_D425_R0.6080.93
149_H322_Q0.6070.93
417_Q422_T0.6070.93
351_C359_Q0.6060.93
191_D195_L0.6050.93
365_R374_F0.6050.93
327_A334_A0.6050.93
499_R502_L0.6040.93
439_I461_G0.6040.93
533_R539_L0.6040.93
199_N202_L0.6020.93
430_F438_V0.6020.93
422_T427_N0.6020.93
459_G463_D0.6020.93
471_S477_I0.6010.93
396_P399_N0.6000.93
462_R465_S0.6000.93
317_I374_F0.5980.93
434_Y446_R0.5970.93
470_V487_A0.5970.93
87_A550_S0.5970.93
482_V487_A0.5960.93
285_D288_Q0.5940.92
249_V253_A0.5940.92
457_V465_S0.5940.92
494_L501_V0.5940.92
441_G444_N0.5930.92
536_F543_R0.5920.92
536_F544_K0.5910.92
416_A426_V0.5900.92
538_K547_A0.5890.92
443_N447_I0.5890.92
436_V444_N0.5890.92
490_S510_L0.5880.92
152_S191_D0.5880.92
470_V489_H0.5880.92
448_R453_D0.5880.92
532_D540_R0.5860.92
529_G533_R0.5860.92
495_T499_R0.5850.92
472_V480_G0.5840.92
352_L358_G0.5830.92
497_A502_L0.5820.92
539_L555_Y0.5820.92
379_T383_L0.5790.91
501_V507_S0.5790.91
155_G158_F0.5790.91
57_Y180_L0.5780.91
533_R552_V0.5750.91
406_P413_S0.5740.91
192_I195_L0.5740.91
411_D417_Q0.5730.91
371_M376_E0.5710.91
537_A541_K0.5700.91
539_L553_P0.5700.91
544_K549_E0.5690.91
230_Y339_F0.5680.91
379_T384_V0.5670.91
434_Y439_I0.5670.91
265_A274_V0.5660.91
224_L251_D0.5660.91
23_Y55_L0.5650.90
535_L542_L0.5650.90
547_A552_V0.5640.90
368_L376_E0.5630.90
212_N218_M0.5630.90
74_L149_H0.5610.90
207_S210_R0.5610.90
419_A422_T0.5610.90
499_R504_G0.5600.90
429_R436_V0.5600.90
423_I426_V0.5590.90
500_P508_L0.5580.90
408_K418_I0.5580.90
442_A447_I0.5580.90
492_L503_R0.5560.90
547_A550_S0.5560.90
398_G401_D0.5560.90
548_D555_Y0.5560.90
432_M435_V0.5550.90
425_R428_Q0.5550.90
492_L502_L0.5550.90
338_L341_D0.5550.90
306_R332_L0.5540.90
224_L311_F0.5540.90
425_R460_M0.5530.89
408_K416_A0.5530.89
347_W356_P0.5510.89
531_Y549_E0.5510.89
414_T423_I0.5500.89
472_V478_H0.5490.89
110_G116_I0.5490.89
539_L544_K0.5480.89
446_R452_H0.5450.89
496_E505_E0.5450.89
83_D280_E0.5450.89
465_S469_W0.5450.89
220_K226_Q0.5450.89
448_R458_Y0.5440.89
380_C388_Y0.5430.89
380_C386_L0.5420.89
440_R445_Q0.5420.89
541_K547_A0.5420.89
480_G483_T0.5410.88
470_V486_I0.5410.88
418_I425_R0.5400.88
468_H471_S0.5400.88
447_I458_Y0.5390.88
471_S475_Q0.5380.88
372_G378_Q0.5380.88
539_L554_P0.5370.88
76_S124_E0.5370.88
348_L356_P0.5360.88
533_R544_K0.5360.88
413_S419_A0.5350.88
547_A556_V0.5340.88
438_V442_A0.5340.88
480_G485_N0.5330.88
546_I553_P0.5330.88
491_A498_A0.5310.88
469_W474_R0.5300.87
405_D410_Y0.5290.87
363_I374_F0.5290.87
95_L131_F0.5290.87
65_N117_R0.5290.87
474_R484_Q0.5270.87
418_I463_D0.5260.87
369_N376_E0.5240.87
431_G436_V0.5240.87
432_M473_I0.5240.87
326_R329_R0.5240.87
541_K551_N0.5230.87
28_P32_E0.5230.87
471_S485_N0.5220.87
160_P163_A0.5220.87
349_R355_K0.5210.87
417_Q421_S0.5210.87
50_G53_K0.5200.86
410_Y414_T0.5200.86
399_N402_I0.5200.86
375_A378_Q0.5200.86
464_K471_S0.5190.86
350_R355_K0.5180.86
475_Q481_L0.5180.86
432_M437_E0.5170.86
454_K457_V0.5160.86
414_T422_T0.5160.86
539_L551_N0.5160.86
424_G427_N0.5160.86
251_D255_R0.5160.86
535_L544_K0.5150.86
481_L501_V0.5150.86
193_V199_N0.5140.86
414_T428_Q0.5140.86
143_L169_R0.5130.86
420_L428_Q0.5120.86
542_L553_P0.5120.86
270_L278_V0.5110.85
64_L68_T0.5110.85
418_I460_M0.5090.85
396_P400_C0.5090.85
540_R551_N0.5080.85
470_V480_G0.5080.85
442_A446_R0.5070.85
534_K546_I0.5070.85
407_P413_S0.5060.85
478_H482_V0.5060.85
347_W358_G0.5060.85
538_K543_R0.5050.85
538_K544_K0.5050.85
363_I378_Q0.5050.85
537_A542_L0.5040.85
550_S556_V0.5030.85
497_A504_G0.5030.85
99_Q107_V0.5020.84
414_T425_R0.5000.84
490_S499_R0.5000.84
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1oywA 1 0.8473 100 0.262 Contact Map
4q48A 1 0.8194 100 0.282 Contact Map
4o3mA 1 0.9557 100 0.283 Contact Map
2v1xA 1 0.8194 100 0.318 Contact Map
4pxaA 1 0.5977 100 0.386 Contact Map
4nhoA 1 0.5846 100 0.392 Contact Map
4ljyA 1 0.6076 100 0.395 Contact Map
2db3A 1 0.5895 100 0.395 Contact Map
4d25A 1 0.5862 100 0.409 Contact Map
4w7sA 2 0.6174 100 0.411 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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