GREMLIN Database
DNLJ - DNA ligase
UniProt: P15042 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10534
Length: 671 (655)
Sequences: 4363 (2849)
Seq/√Len: 111.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
7_Q41_E5.9371.00
621_L626_A4.4171.00
325_R344_E4.4051.00
661_D664_E4.1241.00
18_H30_I3.7091.00
475_F503_A3.3821.00
95_N110_W3.3511.00
526_A622_V3.2651.00
133_A149_V3.2341.00
109_T292_N3.1771.00
17_H21_L3.1301.00
21_L29_E3.1221.00
542_S545_E3.0891.00
601_K637_D3.0221.00
336_A423_V3.0151.00
258_T272_K2.9881.00
363_E366_R2.9511.00
476_K575_E2.8781.00
20_Y25_M2.8701.00
323_F344_E2.8121.00
4_I49_H2.7731.00
323_F374_K2.7701.00
17_H29_E2.7171.00
478_T481_K2.7141.00
129_V158_K2.6751.00
396_P399_T2.5571.00
272_K276_D2.5221.00
337_I415_V2.5081.00
85_V311_V2.4981.00
494_Q498_N2.4321.00
327_V402_V2.4211.00
8_L45_L2.4211.00
536_E577_L2.3701.00
326_D371_I2.3351.00
501_E504_K2.2631.00
95_N99_Q2.2601.00
543_I558_S2.2301.00
535_L583_W2.2281.00
20_Y24_V2.2241.00
53_I60_Q2.2041.00
328_E342_R2.2001.00
650_A654_E2.1961.00
238_T292_N2.1951.00
44_E48_K2.1861.00
127_N166_A2.1861.00
14_T18_H2.1701.00
126_E131_V2.1671.00
126_E167_R2.1571.00
18_H21_L2.1531.00
319_E378_R2.1511.00
476_K579_E2.1471.00
262_S265_E2.1471.00
361_A365_E2.1291.00
539_E570_R2.1211.00
7_Q10_E2.1061.00
574_S578_A2.0771.00
539_E574_S2.0731.00
10_E14_T2.0581.00
130_L149_V2.0551.00
370_R401_E2.0201.00
649_L653_Q2.0151.00
92_L264_E2.0131.00
449_M475_F2.0101.00
650_A653_Q2.0041.00
470_T575_E2.0021.00
479_A497_V1.9531.00
179_A281_G1.9531.00
121_V145_I1.9361.00
638_L660_I1.9121.00
351_V379_R1.9111.00
561_H565_A1.9071.00
196_F202_A1.8751.00
413_S427_T1.8721.00
8_L12_R1.8691.00
603_V638_L1.8671.00
342_R355_N1.8661.00
15_L19_E1.8631.00
610_S643_E1.8531.00
189_R195_V1.8331.00
237_D241_G1.8331.00
177_P180_G1.8261.00
240_L259_L1.8151.00
5_E9_T1.8051.00
641_A659_V1.8001.00
178_Q283_D1.7971.00
245_Q249_W1.7861.00
259_L292_N1.7851.00
12_R54_T1.7831.00
8_L52_L1.7761.00
96_K100_D1.7711.00
43_R59_T1.7671.00
71_S144_D1.7571.00
124_L132_S1.7451.00
18_H38_L1.7401.00
351_V383_V1.7361.00
109_T261_E1.7291.00
240_L244_L1.7271.00
276_D279_T1.7261.00
260_C265_E1.7041.00
641_A645_A1.7021.00
437_K460_D1.7021.00
197_A347_H1.6991.00
88_E271_H1.6971.00
180_G219_P1.6911.00
447_R522_E1.6911.00
154_A221_T1.6871.00
407_H414_D1.6831.00
378_R386_Q1.6821.00
605_L621_L1.6771.00
40_R43_R1.6601.00
376_V389_N1.6491.00
641_A649_L1.6451.00
645_A649_L1.6371.00
123_I155_I1.6301.00
88_E267_L1.6231.00
82_L310_A1.6221.00
329_F402_V1.6201.00
596_S599_A1.6151.00
240_L292_N1.6151.00
454_M496_V1.6131.00
329_F337_I1.6071.00
605_L617_A1.5971.00
377_I387_V1.5901.00
93_A96_K1.5871.00
438_E441_K1.5851.00
266_V289_I1.5771.00
374_K394_E1.5641.00
150_R157_L1.5561.00
73_I132_S1.5511.00
611_Q666_L1.5461.00
40_R90_S1.5421.00
615_D618_K1.5331.00
326_D342_R1.5301.00
663_A667_R1.5291.00
379_R383_V1.5271.00
188_A193_G1.5271.00
214_I217_K1.5231.00
330_Q340_V1.5231.00
206_S215_T1.5041.00
519_E559_H1.5031.00
254_S282_F1.5011.00
612_M666_L1.5001.00
293_S296_Q1.4991.00
72_Q450_D1.4961.00
658_E664_E1.4941.00
31_P34_E1.4911.00
343_L375_V1.4901.00
221_T252_P1.4851.00
618_K622_V1.4811.00
479_A494_Q1.4791.00
321_M394_E1.4781.00
124_L167_R1.4771.00
74_R141_T1.4761.00
149_V174_V1.4751.00
16_R19_E1.4721.00
370_R399_T1.4701.00
440_L459_I1.4691.00
620_R624_L1.4661.00
520_V556_V1.4651.00
21_L25_M1.4601.00
611_Q663_A1.4591.00
524_T556_V1.4541.00
116_L175_F1.4491.00
98_V291_V1.4411.00
83_D306_A1.4391.00
543_I561_H1.4221.00
604_V636_T1.4121.00
39_M43_R1.4111.00
527_G549_V1.4061.00
649_L659_V1.4041.00
365_E401_E1.4021.00
85_V90_S1.4001.00
442_H513_Y1.3991.00
361_A404_F1.3981.00
620_R623_E1.3951.00
493_A497_V1.3931.00
264_E268_A1.3871.00
182_E186_E1.3831.00
61_R157_L1.3801.00
8_L42_L1.3761.00
505_E582_H1.3711.00
534_T537_A1.3691.00
121_V149_V1.3671.00
21_L27_A1.3651.00
567_E571_N1.3651.00
491_K495_N1.3641.00
619_A623_E1.3631.00
602_T627_K1.3611.00
92_L263_A1.3591.00
321_M374_K1.3501.00
92_L267_L1.3471.00
149_V152_I1.3431.00
241_G244_L1.3321.00
539_E564_F1.3281.00
88_E92_L1.3261.00
176_L184_I1.3231.00
458_I488_M1.3221.00
116_L223_F1.3211.00
187_D217_K1.3181.00
237_D293_S1.3171.00
175_F221_T1.3171.00
605_L639_V1.3140.99
543_I547_Q1.3140.99
508_F529_A1.3060.99
8_L59_T1.3010.99
43_R47_T1.2970.99
21_L30_I1.2950.99
490_P494_Q1.2940.99
268_A271_H1.2930.99
40_R44_E1.2900.99
267_L271_H1.2890.99
449_M503_A1.2880.99
403_V406_T1.2870.99
539_E573_I1.2810.99
601_K658_E1.2740.99
186_E190_R1.2710.99
527_G551_D1.2680.99
72_Q141_T1.2670.99
121_V222_F1.2660.99
245_Q248_K1.2660.99
406_T414_D1.2630.99
74_R140_T1.2610.99
261_E265_E1.2570.99
597_P624_L1.2550.99
367_L386_Q1.2520.99
187_D191_T1.2500.99
460_D464_E1.2500.99
87_D90_S1.2490.99
246_F251_L1.2450.99
180_G183_K1.2430.99
273_V287_V1.2420.99
660_I668_L1.2350.99
605_L665_M1.2330.99
18_H28_P1.2270.99
14_T17_H1.2260.99
284_I382_D1.2260.99
479_A483_T1.2240.99
289_I313_F1.2240.99
532_F541_A1.2200.99
155_I222_F1.2190.99
345_P352_L1.2100.99
18_H29_E1.2060.99
95_N263_A1.2050.99
664_E667_R1.2000.99
602_T629_A1.1980.99
451_V500_L1.1980.99
543_I554_I1.1970.99
166_A231_E1.1940.99
13_T17_H1.1910.99
177_P221_T1.1870.99
574_S577_L1.1840.99
183_K187_D1.1800.99
151_T216_A1.1780.99
449_M506_T1.1770.99
76_E124_L1.1710.99
508_F512_L1.1690.99
532_F549_V1.1620.99
536_E540_A1.1590.99
437_K464_E1.1540.99
278_P318_Q1.1520.99
407_H412_G1.1480.99
472_A575_E1.1470.99
448_A513_Y1.1460.99
176_L180_G1.1430.99
7_Q14_T1.1390.99
149_V155_I1.1380.99
472_A572_V1.1370.99
435_Q439_S1.1360.99
80_L302_F1.1350.99
539_E577_L1.1320.98
605_L640_I1.1310.98
461_Q485_L1.1310.98
491_K494_Q1.1280.98
620_R669_L1.1270.98
109_T259_L1.1270.98
637_D658_E1.1210.98
326_D400_R1.1180.98
537_A545_E1.1160.98
638_L658_E1.1150.98
558_S562_N1.1130.98
112_C260_C1.1120.98
130_L155_I1.1110.98
444_V454_M1.1100.98
130_L146_T1.1100.98
9_T13_T1.1080.98
256_R276_D1.1080.98
482_L497_V1.1050.98
497_V501_E1.1030.98
570_R574_S1.0990.98
114_L269_F1.0980.98
466_E469_H1.0960.98
112_C269_F1.0950.98
39_M305_R1.0930.98
410_V433_G1.0890.98
238_T241_G1.0880.98
618_K628_V1.0850.98
443_F449_M1.0840.98
488_M492_S1.0830.98
611_Q662_E1.0820.98
571_N575_E1.0800.98
415_V424_A1.0770.98
437_K463_V1.0750.98
629_A636_T1.0720.98
546_L560_V1.0660.98
612_M617_A1.0660.98
184_I196_F1.0600.98
132_S144_D1.0600.98
19_E61_R1.0540.98
563_F569_N1.0510.98
133_A155_I1.0500.98
410_V434_A1.0480.98
575_E579_E1.0460.97
616_D619_A1.0440.97
14_T38_L1.0430.97
223_F282_F1.0410.97
487_R492_S1.0410.97
244_L247_K1.0370.97
321_M391_V1.0370.97
108_V291_V1.0340.97
603_V621_L1.0320.97
660_I664_E1.0320.97
76_E167_R1.0310.97
343_L377_I1.0250.97
410_V437_K1.0230.97
6_Q10_E1.0210.97
209_Q214_I1.0210.97
414_D566_E1.0200.97
268_A272_K1.0190.97
271_H274_E1.0140.97
114_L273_V1.0110.97
333_R516_G1.0100.97
531_Y545_E1.0100.97
618_K630_G1.0080.97
447_R615_D1.0070.97
340_V355_N1.0050.97
498_N502_K1.0040.97
536_E539_E1.0040.97
664_E668_L1.0000.97
242_R294_L0.9970.97
159_L251_L0.9960.97
378_R388_V0.9960.97
109_T293_S0.9940.97
319_E389_N0.9920.97
380_A386_Q0.9900.96
557_A561_H0.9900.96
353_V383_V0.9870.96
76_E229_V0.9810.96
534_T585_A0.9810.96
265_E268_A0.9810.96
609_L617_A0.9800.96
504_K579_E0.9780.96
320_Q348_V0.9780.96
418_V421_E0.9760.96
111_C240_L0.9760.96
512_L538_L0.9750.96
519_E555_V0.9720.96
440_L468_V0.9710.96
54_T60_Q0.9710.96
349_A379_R0.9690.96
79_M122_S0.9690.96
486_E492_S0.9680.96
361_A417_R0.9660.96
444_V496_V0.9650.96
444_V459_I0.9640.96
111_C239_H0.9630.96
322_T343_L0.9630.96
653_Q659_V0.9620.96
175_F223_F0.9600.96
425_R518_R0.9580.96
638_L668_L0.9540.96
30_I34_E0.9540.96
263_A266_V0.9510.96
183_K186_E0.9480.95
324_V390_V0.9450.95
30_I38_L0.9450.95
362_D422_A0.9430.95
188_A194_K0.9410.95
441_K456_D0.9400.95
186_E189_R0.9390.95
12_R16_R0.9380.95
506_T583_W0.9360.95
19_E39_M0.9340.95
347_H352_L0.9340.95
609_L662_E0.9310.95
170_V246_F0.9300.95
395_R399_T0.9300.95
84_N306_A0.9300.95
481_K484_G0.9290.95
244_L257_V0.9290.95
45_L52_L0.9260.95
102_L296_Q0.9210.95
247_K257_V0.9200.95
181_F199_P0.9200.95
421_E518_R0.9160.95
236_P245_Q0.9160.95
319_E376_V0.9150.95
341_A356_A0.9140.95
34_E37_R0.9140.95
14_T30_I0.9140.95
605_L613_S0.9130.94
89_E92_L0.9130.94
603_V626_A0.9110.94
404_F424_A0.9100.94
631_S636_T0.9090.94
271_H275_E0.9090.94
651_K654_E0.9090.94
640_I660_I0.9080.94
641_A644_A0.9070.94
440_L474_L0.9060.94
532_F545_E0.9060.94
291_V300_L0.9060.94
143_E208_R0.9030.94
479_A490_P0.9020.94
180_G221_T0.8990.94
321_M376_V0.8970.94
376_V391_V0.8940.94
639_V659_V0.8930.94
462_L482_L0.8920.94
519_E556_V0.8910.94
213_R216_A0.8910.94
504_K580_G0.8890.94
362_D417_R0.8880.94
474_L500_L0.8870.94
545_E548_K0.8860.94
10_E41_E0.8850.94
4_I52_L0.8840.93
26_D204_A0.8840.93
263_A267_L0.8830.93
89_E93_A0.8780.93
468_V473_D0.8770.93
99_Q110_W0.8760.93
244_L248_K0.8760.93
363_E367_L0.8720.93
361_A424_A0.8710.93
8_L54_T0.8710.93
530_A622_V0.8680.93
639_V657_I0.8670.93
608_S644_A0.8670.93
121_V174_V0.8650.93
66_P212_P0.8650.93
260_C266_V0.8640.93
49_H52_L0.8620.93
226_G297_Q0.8610.93
502_K505_E0.8610.93
621_L665_M0.8610.93
300_L308_R0.8600.93
324_V389_N0.8580.92
13_T16_R0.8580.92
367_L390_V0.8580.92
508_F538_L0.8560.92
6_Q9_T0.8510.92
601_K638_L0.8500.92
479_A493_A0.8460.92
98_V108_V0.8410.92
91_F270_Y0.8410.92
42_L54_T0.8400.92
577_L583_W0.8390.92
511_F583_W0.8380.92
562_N566_E0.8360.91
180_G184_I0.8360.91
417_R422_A0.8360.91
554_I558_S0.8350.91
502_K506_T0.8330.91
629_A633_S0.8330.91
461_Q486_E0.8310.91
638_L657_I0.8300.91
615_D619_A0.8270.91
547_Q554_I0.8220.91
348_V383_V0.8220.91
55_P129_V0.8210.91
19_E35_Y0.8190.91
159_L165_P0.8190.91
483_T489_G0.8170.90
467_Y481_K0.8170.90
154_A252_P0.8130.90
112_C266_V0.8110.90
506_T510_R0.8100.90
376_V388_V0.8100.90
389_N392_L0.8100.90
227_V242_R0.8080.90
303_V306_A0.8070.90
443_F475_F0.8060.90
470_T572_V0.8060.90
147_S215_T0.8050.90
122_S228_G0.8010.90
188_A191_T0.8000.90
613_S616_D0.7990.89
373_D395_R0.7980.89
634_K639_V0.7970.89
188_A195_V0.7960.89
112_C289_I0.7960.89
532_F546_L0.7950.89
116_L254_S0.7950.89
624_L669_L0.7910.89
119_L203_A0.7900.89
327_V370_R0.7900.89
448_A514_A0.7890.89
46_E57_S0.7890.89
483_T493_A0.7860.89
46_E58_P0.7860.89
651_K655_L0.7860.89
243_L253_V0.7830.89
114_L256_R0.7830.89
69_A210_L0.7820.88
258_T269_F0.7810.88
39_M59_T0.7810.88
130_L133_A0.7800.88
329_F404_F0.7800.88
240_L257_V0.7800.88
95_N266_V0.7740.88
76_E132_S0.7730.88
509_A586_P0.7730.88
82_L288_V0.7720.88
44_E47_T0.7720.88
247_K255_D0.7710.88
174_V207_L0.7710.88
46_E59_T0.7700.88
511_F581_V0.7690.88
33_A37_R0.7690.88
9_T12_R0.7670.87
53_I56_D0.7640.87
461_Q487_R0.7630.87
660_I665_M0.7630.87
145_I174_V0.7620.87
531_Y548_K0.7610.87
602_T637_D0.7590.87
167_R229_V0.7590.87
203_A220_L0.7580.87
603_V660_I0.7530.87
16_R56_D0.7520.86
604_V629_A0.7510.86
483_T490_P0.7510.86
113_E290_K0.7500.86
269_F272_K0.7490.86
112_C287_V0.7490.86
91_F289_I0.7480.86
537_A540_A0.7480.86
224_C251_L0.7470.86
467_Y485_L0.7450.86
524_T552_V0.7440.86
481_K489_G0.7430.86
174_V220_L0.7430.86
483_T497_V0.7430.86
468_V474_L0.7420.86
463_V468_V0.7420.86
270_Y313_F0.7410.86
436_R463_V0.7400.86
183_K219_P0.7390.85
658_E668_L0.7370.85
595_D624_L0.7350.85
68_A210_L0.7350.85
207_L215_T0.7330.85
610_S663_A0.7320.85
73_I144_D0.7310.85
454_M474_L0.7310.85
520_V560_V0.7280.85
164_I249_W0.7280.85
123_I133_A0.7280.85
488_M493_A0.7270.85
328_E340_V0.7260.84
471_P572_V0.7260.84
182_E189_R0.7260.84
374_K391_V0.7240.84
8_L49_H0.7230.84
12_R53_I0.7230.84
99_Q108_V0.7220.84
296_Q299_Q0.7220.84
264_E267_L0.7220.84
492_S495_N0.7210.84
110_W263_A0.7210.84
617_A665_M0.7200.84
76_E122_S0.7170.84
67_L147_S0.7170.84
565_A570_R0.7170.84
297_Q309_W0.7160.84
40_R85_V0.7160.84
445_S448_A0.7160.84
368_G401_E0.7150.84
440_L471_P0.7150.84
392_L395_R0.7150.84
236_P241_G0.7140.83
442_H448_A0.7130.83
123_I130_L0.7110.83
461_Q488_M0.7110.83
621_L640_I0.7100.83
102_L106_E0.7090.83
320_Q377_I0.7060.83
595_D598_F0.7060.83
91_F266_V0.7060.83
348_V351_V0.7050.83
524_T560_V0.7040.83
495_N498_N0.7030.83
168_L249_W0.7030.83
413_S428_G0.7030.83
642_G646_G0.7000.82
168_L246_F0.7000.82
431_I568_S0.7000.82
324_V375_V0.7000.82
371_I400_R0.6990.82
77_V229_V0.6990.82
102_L108_V0.6990.82
348_V377_I0.6990.82
523_A527_G0.6980.82
568_S571_N0.6970.82
370_R400_R0.6960.82
178_Q281_G0.6950.82
111_C243_L0.6940.82
368_G395_R0.6920.82
605_L628_V0.6920.82
546_L552_V0.6910.81
319_E388_V0.6910.81
331_V337_I0.6910.81
274_E316_P0.6910.81
551_D556_V0.6880.81
566_E569_N0.6880.81
74_R134_A0.6870.81
603_V640_I0.6860.81
598_F668_L0.6860.81
315_F382_D0.6860.81
107_K261_E0.6850.81
126_E132_S0.6830.81
55_P60_Q0.6820.81
85_V91_F0.6800.80
211_D218_R0.6800.80
389_N393_S0.6800.80
239_H297_Q0.6780.80
620_R666_L0.6780.80
357_T383_V0.6780.80
456_D460_D0.6780.80
56_D158_K0.6760.80
323_F394_E0.6750.80
258_T265_E0.6740.80
165_P249_W0.6740.80
120_A225_Y0.6730.80
604_V628_V0.6730.80
628_V665_M0.6720.80
179_A183_K0.6720.80
629_A639_V0.6710.80
247_K253_V0.6710.80
24_V64_A0.6690.79
400_R403_V0.6690.79
17_H30_I0.6680.79
328_E355_N0.6670.79
605_L612_M0.6670.79
42_L45_L0.6670.79
571_N574_S0.6670.79
524_T551_D0.6660.79
632_V639_V0.6640.79
349_A382_D0.6640.79
238_T294_L0.6630.79
159_L166_A0.6620.79
449_M581_V0.6620.79
151_T215_T0.6620.79
266_V313_F0.6620.79
153_R157_L0.6600.78
594_I597_P0.6590.78
610_S662_E0.6580.78
12_R42_L0.6540.78
133_A145_I0.6530.78
591_A594_I0.6530.78
110_W289_I0.6530.78
577_L581_V0.6510.77
42_L59_T0.6510.77
98_V300_L0.6500.77
91_F313_F0.6500.77
98_V101_R0.6500.77
533_G537_A0.6500.77
365_E422_A0.6480.77
269_F287_V0.6480.77
439_S563_F0.6480.77
274_E315_F0.6470.77
508_F535_L0.6470.77
184_I219_P0.6450.77
417_R420_G0.6450.77
7_Q45_L0.6450.77
498_N501_E0.6440.77
84_N311_V0.6410.76
24_V154_A0.6400.76
16_R61_R0.6390.76
592_E596_S0.6370.76
392_L396_P0.6370.76
482_L493_A0.6350.76
189_R194_K0.6340.76
511_F514_A0.6340.76
531_Y549_V0.6330.75
534_T584_P0.6330.75
66_P69_A0.6320.75
429_G566_E0.6310.75
91_F95_N0.6300.75
224_C253_V0.6300.75
369_L390_V0.6300.75
20_Y160_H0.6300.75
617_A640_I0.6280.75
120_A226_G0.6260.75
223_F280_L0.6260.75
640_I665_M0.6260.75
179_A182_E0.6250.75
95_N98_V0.6240.74
111_C257_V0.6240.74
109_T238_T0.6240.74
610_S644_A0.6230.74
462_L466_E0.6230.74
636_T639_V0.6230.74
416_E427_T0.6230.74
506_T511_F0.6220.74
368_G392_L0.6220.74
471_P514_A0.6200.74
608_S613_S0.6200.74
450_D506_T0.6190.74
611_Q617_A0.6180.74
528_L538_L0.6180.74
507_T582_H0.6180.74
465_K485_L0.6170.74
606_T609_L0.6160.74
462_L474_L0.6160.74
304_A523_A0.6150.73
152_I155_I0.6150.73
160_H251_L0.6150.73
361_A402_V0.6130.73
153_R219_P0.6130.73
61_R154_A0.6120.73
284_I315_F0.6110.73
399_T402_V0.6110.73
431_I436_R0.6100.73
411_C434_A0.6080.73
140_T526_A0.6080.73
363_E369_L0.6070.72
93_A97_R0.6070.72
213_R217_K0.6060.72
4_I7_Q0.6050.72
14_T41_E0.6050.72
229_V232_G0.6050.72
31_P321_M0.6040.72
79_M134_A0.6030.72
223_F254_S0.6020.72
206_S209_Q0.6010.72
603_V637_D0.6010.72
127_N167_R0.6000.72
274_E382_D0.6000.72
537_A541_A0.6000.72
15_L39_M0.5990.71
452_D502_K0.5970.71
154_A175_F0.5970.71
336_A422_A0.5960.71
535_L539_E0.5960.71
447_R513_Y0.5960.71
480_G483_T0.5960.71
361_A415_V0.5960.71
374_K396_P0.5950.71
153_R216_A0.5950.71
325_R328_E0.5950.71
370_R402_V0.5940.71
602_T630_G0.5940.71
295_A299_Q0.5940.71
86_F208_R0.5930.71
619_A622_V0.5920.71
42_L58_P0.5910.70
184_I202_A0.5900.70
629_A635_K0.5900.70
141_T510_R0.5890.70
212_P216_A0.5890.70
474_L493_A0.5880.70
145_I149_V0.5880.70
284_I383_V0.5880.70
43_R83_D0.5870.70
575_E578_A0.5870.70
508_F583_W0.5870.70
639_V655_L0.5870.70
61_R151_T0.5860.70
449_M583_W0.5860.70
188_A210_L0.5840.70
41_E44_E0.5840.70
147_S212_P0.5840.70
123_I251_L0.5840.70
507_T584_P0.5840.70
243_L257_V0.5830.69
531_Y537_A0.5820.69
274_E284_I0.5820.69
19_E53_I0.5820.69
79_M120_A0.5810.69
505_E584_P0.5810.69
197_A352_L0.5810.69
40_R84_N0.5810.69
12_R56_D0.5790.69
341_A387_V0.5780.69
70_F148_N0.5780.69
23_H39_M0.5780.69
539_E542_S0.5770.69
17_H20_Y0.5770.69
329_F361_A0.5770.69
206_S218_R0.5770.69
533_G587_I0.5760.68
293_S297_Q0.5760.68
495_N499_A0.5760.68
483_T494_Q0.5750.68
5_E52_L0.5750.68
86_F378_R0.5750.68
538_L564_F0.5750.68
487_R493_A0.5740.68
602_T635_K0.5740.68
605_L609_L0.5730.68
567_E570_R0.5720.68
151_T219_P0.5720.68
458_I496_V0.5700.68
449_M514_A0.5700.68
478_T493_A0.5690.68
509_A526_A0.5690.68
7_Q38_L0.5680.67
370_R397_E0.5680.67
330_Q342_R0.5680.67
461_Q465_K0.5670.67
374_K395_R0.5650.67
236_P242_R0.5640.67
485_L488_M0.5640.67
487_R551_D0.5630.67
94_F551_D0.5620.67
16_R53_I0.5620.67
605_L618_K0.5610.66
83_D311_V0.5610.66
67_L210_L0.5600.66
209_Q215_T0.5600.66
12_R45_L0.5590.66
478_T501_E0.5590.66
357_T363_E0.5580.66
275_E278_P0.5580.66
122_S134_A0.5570.66
547_Q552_V0.5570.66
270_Y274_E0.5570.66
486_E489_G0.5570.66
549_V552_V0.5560.66
18_H31_P0.5560.66
511_F576_L0.5560.66
123_I149_V0.5550.66
103_K108_V0.5550.66
477_L497_V0.5550.66
227_V246_F0.5550.66
408_C426_C0.5540.65
437_K459_I0.5540.65
596_S603_V0.5530.65
176_L219_P0.5530.65
225_Y282_F0.5500.65
147_S150_R0.5500.65
353_V377_I0.5500.65
261_E292_N0.5500.65
19_E23_H0.5490.65
189_R192_G0.5490.65
86_F270_Y0.5490.65
603_V668_L0.5490.65
329_F415_V0.5480.65
462_L465_K0.5480.65
472_A579_E0.5480.65
596_S624_L0.5480.65
79_M169_E0.5480.65
547_Q561_H0.5470.65
633_S655_L0.5470.65
347_H351_V0.5470.65
177_P202_A0.5470.65
42_L46_E0.5470.65
73_I131_V0.5470.65
277_R382_D0.5450.64
546_L551_D0.5450.64
242_R246_F0.5450.64
349_A383_V0.5450.64
122_S169_E0.5440.64
444_V451_V0.5440.64
160_H248_K0.5430.64
86_F316_P0.5430.64
386_Q404_F0.5430.64
489_G492_S0.5430.64
197_A349_A0.5420.64
330_Q338_T0.5420.64
155_I252_P0.5410.64
654_E657_I0.5400.64
26_D208_R0.5390.63
476_K578_A0.5390.63
374_K399_T0.5390.63
665_M669_L0.5380.63
325_R342_R0.5380.63
364_I404_F0.5380.63
47_T53_I0.5380.63
5_E8_L0.5370.63
273_V284_I0.5370.63
92_L96_K0.5370.63
612_M665_M0.5370.63
319_E386_Q0.5370.63
365_E368_G0.5360.63
283_D318_Q0.5360.63
514_A529_A0.5350.63
610_S624_L0.5340.63
124_L134_A0.5340.63
70_F151_T0.5330.63
91_F263_A0.5320.62
465_K486_E0.5320.62
598_F669_L0.5320.62
351_V382_D0.5320.62
441_K460_D0.5320.62
397_E400_R0.5320.62
209_Q316_P0.5310.62
270_Y287_V0.5310.62
518_R559_H0.5310.62
108_V296_Q0.5300.62
395_R400_R0.5300.62
130_L157_L0.5290.62
336_A425_R0.5290.62
436_R439_S0.5280.62
408_C411_C0.5280.62
509_A585_A0.5280.62
552_V560_V0.5270.62
471_P576_L0.5270.62
405_P424_A0.5260.62
14_T34_E0.5240.61
602_T638_L0.5240.61
540_A570_R0.5240.61
443_F581_V0.5240.61
621_L628_V0.5240.61
24_V66_P0.5230.61
448_A510_R0.5230.61
499_A502_K0.5230.61
291_V296_Q0.5220.61
371_I399_T0.5220.61
8_L53_I0.5220.61
501_E505_E0.5210.61
646_G649_L0.5210.61
114_L287_V0.5200.61
15_L42_L0.5200.61
209_Q380_A0.5190.61
267_L270_Y0.5190.61
634_K645_A0.5180.60
135_T145_I0.5180.60
8_L15_L0.5170.60
446_R452_D0.5160.60
556_V559_H0.5160.60
469_H473_D0.5150.60
620_R665_M0.5150.60
392_L397_E0.5150.60
367_L370_R0.5150.60
415_V427_T0.5150.60
119_L209_Q0.5150.60
15_L30_I0.5140.60
225_Y254_S0.5140.60
239_H242_R0.5140.60
164_I245_Q0.5140.60
278_P284_I0.5140.60
459_I496_V0.5130.60
31_P37_R0.5120.59
228_G242_R0.5120.59
596_S637_D0.5120.59
227_V236_P0.5120.59
436_R440_L0.5110.59
610_S665_M0.5110.59
116_L255_D0.5100.59
84_N90_S0.5100.59
35_Y39_M0.5100.59
26_D143_E0.5090.59
543_I557_A0.5090.59
506_T582_H0.5080.59
223_F253_V0.5080.59
457_K460_D0.5080.59
594_I599_A0.5080.59
73_I134_A0.5070.59
175_F252_P0.5070.59
485_L489_G0.5060.59
535_L538_L0.5060.59
572_V575_E0.5060.59
362_D365_E0.5060.59
138_D141_T0.5050.58
270_Y379_R0.5050.58
112_C273_V0.5050.58
457_K461_Q0.5040.58
14_T21_L0.5040.58
441_K459_I0.5030.58
593_E623_E0.5030.58
626_A665_M0.5020.58
567_E574_S0.5020.58
415_V428_G0.5020.58
511_F535_L0.5020.58
595_D599_A0.5020.58
513_Y522_E0.5010.58
164_I167_R0.5010.58
357_T386_Q0.5010.58
532_F538_L0.5010.58
370_R392_L0.5000.58
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2owoA 1 0.8733 100 0.02 Contact Map
1dgsA 1 0.8569 100 0.047 Contact Map
3sgiA 1 0.5991 100 0.141 Contact Map
4glxA 1 0.8539 100 0.182 Contact Map
3uq8A 1 0.4784 100 0.527 Contact Map
3jslA 2 0.459 100 0.537 Contact Map
1zauA 1 0.4694 100 0.537 Contact Map
4lh6A 1 0.4709 100 0.541 Contact Map
1b04A 1 0.4605 100 0.546 Contact Map
4glwA 2 0.4203 100 0.551 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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