HELD - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

HELD - Helicase IV

UniProt:	P15038	Sequences: MELKATTLGKRLAQHPYDRAVILNAGIKVSGDRHEYLIPFNQLLAIHCKRGLVWGELEFVLPDEKVVRLHGTEWGETQRFYHHLDAHWRRWSGEMSEIASGVLRQQLDLIATRTGENKWLTREQTSGVQQQIRQALSALPLPVNRLEEFDNCREAWRKCQAWLKDIESARLQHNQAYTEAMLTEYADFFRQVESSPLNPAQARAVVNGEHSLLVLAGAGSGKTSVLVARAGWLLARGEASPEQILLLAFGRKAAEEMDERIRERLHTEDITARTFHALALHIIQQGSKKVPIVSKLENDTAARHELFIAEWRKQCSEKKAQAKGWRQWLTEEMQWSVPEGNFWDDEKLQRRLASRLDRWVSLMRMHGGAQAEMIASAPEEIRDLFSKRIKLMAPLLKAWKGALKAENAVDFSGLIHQAIVILEKGRFISPWKHILVDEFQDISPQRAALLAALRKQNSQTTLFAVGDDWQAIYRFSGAQMSLTTAFHENFGEGERCDLDTTYRFNSRIGEVANRFIQQNPGQLKKPLNSLTNGDKKAVTLLDESQLDALLDKLSGYAKPEERILILARYHHMRPASLEKAATRWPKLQIDFMTIHASKGQQADYVIIVGLQEGSDGFPAAARESIMEEALLPPVEDFPDAEERRLMYVALTRARHRVWALFNKENPSPFVEILKNLDVPVARKP	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10426
Length:	684 (571)
Sequences:	2271 (1993)
Seq/√Len:	83.4

ECOLI - HELD UVRD
BACSU - HELD YJCD PCRA
HALSA - Q9HNB7 Q9HPR8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
567_A	573_R	4.577	1.00
417_Q	424_K	4.532	1.00
416_H	424_K	3.622	1.00
507_R	532_N	3.498	1.00
299_D	304_H	3.285	1.00
415_I	418_A	3.211	1.00
542_D	545_Q	3.143	1.00
311_W	315_C	3.095	1.00
418_A	422_L	2.940	1.00
413_G	417_Q	2.889	1.00
418_A	424_K	2.858	1.00
418_A	421_I	2.826	1.00
413_G	418_A	2.731	1.00
594_I	649_A	2.725	1.00
359_W	363_M	2.718	1.00
197_L	205_V	2.694	1.00
348_L	352_L	2.645	1.00
512_A	651_T	2.605	1.00
304_H	311_W	2.600	1.00
298_N	301_A	2.549	1.00
414_L	418_A	2.536	1.00
607_I	649_A	2.459	1.00
411_F	418_A	2.455	1.00
339_E	342_F	2.436	1.00
411_F	414_L	2.379	1.00
399_W	403_L	2.361	1.00
134_Q	137_S	2.333	1.00
420_V	423_E	2.329	1.00
198_N	502_Y	2.326	1.00
396_L	400_K	2.302	1.00
415_I	419_I	2.288	1.00
576_S	591_F	2.270	1.00
415_I	422_L	2.244	1.00
595_H	645_L	2.229	1.00
416_H	419_I	2.172	1.00
243_Q	432_K	2.143	1.00
553_L	565_I	2.135	1.00
233_L	433_H	2.106	1.00
340_G	345_D	2.102	1.00
562_R	603_D	2.072	1.00
409_V	414_L	2.063	1.00
441_D	598_K	2.001	1.00
336_S	340_G	1.996	1.00
344_D	348_L	1.966	1.00
419_I	424_K	1.964	1.00
414_L	419_I	1.957	1.00
336_S	339_E	1.946	1.00
487_H	490_F	1.942	1.00
420_V	424_K	1.919	1.00
204_A	214_V	1.887	1.00
299_D	311_W	1.886	1.00
154_E	168_S	1.885	1.00
534_D	656_R	1.867	1.00
572_M	609_G	1.861	1.00
552_K	555_G	1.855	1.00
358_R	362_L	1.850	1.00
256_E	260_R	1.845	1.00
305_E	309_A	1.839	1.00
415_I	421_I	1.823	1.00
335_W	339_E	1.803	1.00
533_G	536_K	1.803	1.00
299_D	308_I	1.785	1.00
347_K	350_R	1.759	1.00
344_D	347_K	1.753	1.00
156_W	163_L	1.750	1.00
415_I	424_K	1.749	1.00
385_F	389_I	1.743	1.00
299_D	302_A	1.740	1.00
356_L	360_V	1.738	1.00
381_I	385_F	1.731	1.00
444_P	485_A	1.727	1.00
419_I	423_E	1.718	1.00
593_T	596_A	1.704	1.00
390_K	393_A	1.687	1.00
301_A	304_H	1.682	1.00
421_I	424_K	1.679	1.00
564_L	602_A	1.675	1.00
311_W	316_S	1.673	1.00
551_D	554_S	1.670	1.00
346_E	349_Q	1.666	1.00
340_G	344_D	1.660	1.00
547_D	551_D	1.657	1.00
549_L	660_L	1.634	1.00
606_I	660_L	1.627	1.00
336_S	343_W	1.625	1.00
419_I	422_L	1.620	1.00
389_I	392_M	1.619	1.00
370_Q	373_M	1.601	1.00
296_L	299_D	1.591	1.00
345_D	348_L	1.586	1.00
548_A	551_D	1.586	1.00
336_S	344_D	1.584	1.00
345_D	349_Q	1.582	1.00
480_M	483_T	1.580	1.00
300_T	308_I	1.575	1.00
335_W	341_N	1.574	1.00
590_D	600_Q	1.571	1.00
343_W	351_R	1.569	1.00
56_E	62_P	1.559	1.00
348_L	351_R	1.558	1.00
416_H	420_V	1.557	1.00
414_L	423_E	1.551	1.00
569_Y	572_M	1.542	1.00
407_N	413_G	1.539	1.00
506_S	510_E	1.537	1.00
340_G	343_W	1.537	1.00
380_E	384_L	1.529	1.00
417_Q	422_L	1.527	1.00
384_L	387_K	1.513	0.99
100_S	150_D	1.510	0.99
63_D	66_V	1.510	0.99
302_A	305_E	1.506	0.99
396_L	399_W	1.506	0.99
339_E	343_W	1.503	0.99
304_H	307_F	1.501	0.99
511_V	650_L	1.499	0.99
416_H	421_I	1.497	0.99
304_H	316_S	1.496	0.99
509_G	512_A	1.486	0.99
534_D	537_A	1.483	0.99
483_T	489_N	1.481	0.99
357_D	364_R	1.467	0.99
61_L	64_E	1.467	0.99
508_I	653_A	1.464	0.99
341_N	344_D	1.464	0.99
604_Y	656_R	1.460	0.99
360_V	365_M	1.460	0.99
552_K	660_L	1.456	0.99
385_F	390_K	1.454	0.99
417_Q	423_E	1.454	0.99
340_G	348_L	1.453	0.99
300_T	312_R	1.453	0.99
417_Q	420_V	1.443	0.99
417_Q	421_I	1.439	0.99
360_V	364_R	1.438	0.99
501_T	504_F	1.431	0.99
207_N	494_E	1.426	0.99
395_L	399_W	1.426	0.99
60_V	66_V	1.423	0.99
311_W	314_Q	1.420	0.99
66_V	69_L	1.419	0.99
479_Q	483_T	1.409	0.99
410_D	414_L	1.401	0.99
46_I	50_R	1.391	0.99
295_K	298_N	1.391	0.99
419_I	425_G	1.388	0.99
483_T	487_H	1.386	0.99
422_L	425_G	1.385	0.99
612_E	664_E	1.384	0.99
297_E	300_T	1.384	0.99
602_A	605_V	1.384	0.99
335_W	342_F	1.382	0.99
346_E	351_R	1.373	0.99
566_L	597_S	1.371	0.99
368_G	374_I	1.370	0.99
439_F	447_A	1.364	0.99
299_D	312_R	1.353	0.99
351_R	359_W	1.353	0.99
345_D	353_A	1.348	0.99
567_A	576_S	1.344	0.99
293_V	296_L	1.342	0.99
229_R	463_F	1.341	0.99
359_W	364_R	1.341	0.99
564_L	605_V	1.331	0.99
300_T	303_R	1.324	0.99
377_A	381_I	1.315	0.99
409_V	413_G	1.312	0.98
408_A	411_F	1.309	0.98
545_Q	660_L	1.308	0.98
60_V	63_D	1.303	0.98
336_S	341_N	1.294	0.98
386_S	389_I	1.293	0.98
349_Q	352_L	1.293	0.98
301_A	308_I	1.284	0.98
77_T	81_Y	1.283	0.98
387_K	392_M	1.283	0.98
415_I	420_V	1.279	0.98
344_D	349_Q	1.275	0.98
306_L	309_A	1.275	0.98
397_K	400_K	1.273	0.98
343_W	348_L	1.269	0.98
359_W	362_L	1.265	0.98
563_I	589_I	1.264	0.98
389_I	393_A	1.263	0.98
412_S	424_K	1.262	0.98
75_G	79_R	1.262	0.98
382_R	385_F	1.262	0.98
416_H	425_G	1.261	0.98
480_M	486_F	1.260	0.98
300_T	304_H	1.253	0.98
556_Y	604_Y	1.251	0.98
400_K	404_K	1.250	0.98
540_L	661_F	1.246	0.98
295_K	299_D	1.244	0.98
440_Q	647_Y	1.238	0.98
412_S	418_A	1.237	0.98
482_L	487_H	1.236	0.98
341_N	349_Q	1.233	0.98
607_I	610_L	1.231	0.98
231_G	235_A	1.231	0.98
371_A	377_A	1.230	0.98
246_L	257_M	1.228	0.98
363_M	367_G	1.224	0.98
295_K	300_T	1.222	0.98
412_S	416_H	1.221	0.98
335_W	340_G	1.218	0.98
273_R	278_L	1.217	0.98
337_V	344_D	1.215	0.97
299_D	303_R	1.208	0.97
388_R	391_L	1.206	0.97
412_S	417_Q	1.204	0.97
277_A	280_L	1.201	0.97
548_A	552_K	1.199	0.97
351_R	355_R	1.198	0.97
537_A	658_W	1.197	0.97
175_Q	178_T	1.197	0.97
447_A	464_A	1.195	0.97
413_G	416_H	1.194	0.97
598_K	647_Y	1.192	0.97
120_L	129_Q	1.192	0.97
335_W	348_L	1.192	0.97
296_L	304_H	1.187	0.97
420_V	425_G	1.187	0.97
307_F	316_S	1.187	0.97
370_Q	374_I	1.185	0.97
131_Q	141_L	1.184	0.97
293_V	297_E	1.177	0.97
299_D	305_E	1.167	0.97
418_A	423_E	1.165	0.97
563_I	604_Y	1.161	0.97
202_A	206_V	1.161	0.97
411_F	421_I	1.161	0.97
306_L	310_E	1.160	0.97
398_A	401_G	1.157	0.97
59_F	70_H	1.156	0.97
546_L	550_L	1.143	0.96
304_H	315_C	1.141	0.96
309_A	312_R	1.139	0.96
358_R	365_M	1.139	0.96
472_I	645_L	1.137	0.96
552_K	556_Y	1.136	0.96
52_L	56_E	1.133	0.96
364_R	367_G	1.133	0.96
304_H	308_I	1.126	0.96
368_G	375_A	1.125	0.96
355_R	363_M	1.124	0.96
411_F	415_I	1.110	0.96
343_W	352_L	1.107	0.96
385_F	392_M	1.104	0.96
337_V	343_W	1.103	0.96
371_A	374_I	1.101	0.96
307_F	310_E	1.098	0.95
75_G	78_Q	1.095	0.95
308_I	315_C	1.091	0.95
340_G	351_R	1.085	0.95
550_L	554_S	1.085	0.95
349_Q	355_R	1.084	0.95
386_S	391_L	1.084	0.95
413_G	424_K	1.083	0.95
226_L	435_L	1.082	0.95
50_R	53_V	1.082	0.95
64_E	67_V	1.081	0.95
360_V	363_M	1.078	0.95
418_A	425_G	1.076	0.95
362_L	367_G	1.076	0.95
347_K	351_R	1.076	0.95
293_V	300_T	1.075	0.95
395_L	403_L	1.075	0.95
339_E	348_L	1.074	0.95
307_F	311_W	1.074	0.95
305_E	311_W	1.071	0.95
421_I	425_G	1.070	0.95
553_L	557_A	1.070	0.95
352_L	356_L	1.067	0.95
468_D	471_A	1.066	0.95
228_A	256_E	1.063	0.95
412_S	421_I	1.063	0.95
346_E	352_L	1.063	0.95
301_A	309_A	1.062	0.95
607_I	646_M	1.062	0.95
400_K	403_L	1.061	0.95
574_P	578_E	1.061	0.95
341_N	345_D	1.057	0.94
566_L	592_M	1.056	0.94
385_F	393_A	1.056	0.94
300_T	311_W	1.053	0.94
46_I	53_V	1.050	0.94
414_L	417_Q	1.049	0.94
51_G	54_W	1.049	0.94
360_V	367_G	1.047	0.94
350_R	354_S	1.046	0.94
116_E	132_I	1.038	0.94
77_T	80_F	1.037	0.94
340_G	352_L	1.037	0.94
372_E	376_S	1.037	0.94
116_E	141_L	1.036	0.94
504_F	509_G	1.034	0.94
335_W	351_R	1.031	0.94
250_G	504_F	1.031	0.94
297_E	307_F	1.027	0.93
335_W	343_W	1.026	0.93
71_G	75_G	1.024	0.93
231_G	261_I	1.024	0.93
210_H	461_T	1.020	0.93
356_L	368_G	1.019	0.93
228_A	232_W	1.014	0.93
313_K	317_E	1.014	0.93
381_I	389_I	1.013	0.93
47_H	50_R	1.012	0.93
441_D	647_Y	1.011	0.93
369_A	372_E	1.004	0.93
67_V	71_G	1.002	0.93
554_S	558_K	1.001	0.93
88_W	91_W	0.998	0.93
472_I	644_R	0.996	0.92
298_N	304_H	0.994	0.92
339_E	351_R	0.992	0.92
218_A	472_I	0.991	0.92
356_L	362_L	0.991	0.92
373_M	378_P	0.983	0.92
368_G	371_A	0.980	0.92
214_V	463_F	0.978	0.92
440_Q	598_K	0.976	0.92
416_H	423_E	0.976	0.92
298_N	311_W	0.975	0.92
215_L	468_D	0.974	0.92
63_D	72_T	0.973	0.92
566_L	594_I	0.972	0.91
388_R	392_M	0.960	0.91
340_G	353_A	0.959	0.91
417_Q	425_G	0.958	0.91
253_A	260_R	0.956	0.91
483_T	490_F	0.956	0.91
367_G	376_S	0.953	0.91
300_T	315_C	0.952	0.91
220_S	500_T	0.952	0.91
50_R	54_W	0.950	0.91
312_R	316_S	0.949	0.90
386_S	390_K	0.947	0.90
568_R	642_E	0.946	0.90
369_A	373_M	0.945	0.90
411_F	416_H	0.945	0.90
68_R	72_T	0.944	0.90
399_W	402_A	0.944	0.90
58_E	61_L	0.936	0.90
385_F	388_R	0.932	0.90
53_V	62_P	0.930	0.90
552_K	606_I	0.929	0.90
213_L	464_A	0.923	0.89
256_E	600_Q	0.922	0.89
336_S	348_L	0.922	0.89
116_E	137_S	0.921	0.89
383_D	386_S	0.919	0.89
569_Y	595_H	0.918	0.89
537_A	540_L	0.916	0.89
437_D	502_Y	0.916	0.89
451_A	455_K	0.915	0.89
372_E	378_P	0.915	0.89
440_Q	568_R	0.914	0.89
114_T	135_A	0.913	0.89
61_L	65_K	0.912	0.89
387_K	391_L	0.912	0.89
381_I	391_L	0.911	0.89
225_V	228_A	0.909	0.89
352_L	359_W	0.909	0.89
384_L	389_I	0.907	0.88
56_E	61_L	0.907	0.88
349_Q	353_A	0.906	0.88
361_S	367_G	0.906	0.88
348_L	353_A	0.905	0.88
339_E	345_D	0.902	0.88
357_D	367_G	0.902	0.88
441_D	472_I	0.897	0.88
76_E	79_R	0.897	0.88
304_H	310_E	0.897	0.88
205_V	228_A	0.896	0.88
295_K	301_A	0.895	0.88
395_L	400_K	0.894	0.88
345_D	350_R	0.894	0.88
232_W	256_E	0.892	0.88
592_M	597_S	0.889	0.87
642_E	646_M	0.889	0.87
61_L	66_V	0.886	0.87
347_K	355_R	0.886	0.87
374_I	377_A	0.885	0.87
546_L	579_K	0.883	0.87
387_K	390_K	0.882	0.87
304_H	312_R	0.880	0.87
413_G	419_I	0.878	0.87
335_W	338_P	0.878	0.87
63_D	67_V	0.876	0.87
478_A	483_T	0.871	0.86
49_K	53_V	0.869	0.86
193_E	197_L	0.869	0.86
84_L	88_W	0.868	0.86
439_F	464_A	0.866	0.86
411_F	420_V	0.864	0.86
335_W	345_D	0.863	0.86
86_A	90_R	0.863	0.86
340_G	349_Q	0.863	0.86
371_A	376_S	0.863	0.86
373_M	376_S	0.861	0.86
341_N	348_L	0.860	0.86
358_R	361_S	0.860	0.86
501_T	595_H	0.856	0.85
415_I	423_E	0.855	0.85
163_L	166_I	0.854	0.85
273_R	277_A	0.848	0.85
305_E	308_I	0.847	0.85
565_I	576_S	0.846	0.85
79_R	91_W	0.845	0.85
433_H	461_T	0.843	0.84
135_A	141_L	0.842	0.84
483_T	486_F	0.841	0.84
178_T	234_L	0.841	0.84
129_Q	132_I	0.838	0.84
46_I	49_K	0.838	0.84
336_S	352_L	0.838	0.84
73_E	77_T	0.837	0.84
217_G	512_A	0.837	0.84
53_V	60_V	0.837	0.84
573_R	591_F	0.835	0.84
409_V	418_A	0.835	0.84
395_L	398_A	0.833	0.84
539_T	658_W	0.833	0.84
138_A	142_P	0.832	0.84
300_T	305_E	0.831	0.84
53_V	57_L	0.830	0.84
295_K	307_F	0.830	0.84
382_R	388_R	0.830	0.84
415_I	425_G	0.829	0.83
365_M	369_A	0.828	0.83
55_G	59_F	0.828	0.83
95_M	99_A	0.827	0.83
386_S	394_P	0.826	0.83
143_V	148_E	0.826	0.83
45_A	57_L	0.825	0.83
131_Q	135_A	0.823	0.83
386_S	393_A	0.820	0.83
131_Q	137_S	0.820	0.83
412_S	422_L	0.820	0.83
352_L	355_R	0.818	0.83
338_P	342_F	0.818	0.83
356_L	378_P	0.818	0.83
391_L	394_P	0.817	0.83
59_F	62_P	0.817	0.83
441_D	512_A	0.816	0.82
103_L	151_N	0.815	0.82
347_K	353_A	0.814	0.82
97_E	141_L	0.813	0.82
248_A	253_A	0.810	0.82
370_Q	375_A	0.809	0.82
475_F	478_A	0.807	0.82
54_W	60_V	0.805	0.82
73_E	85_D	0.805	0.82
336_S	347_K	0.805	0.82
337_V	342_F	0.803	0.81
408_A	413_G	0.802	0.81
208_G	236_R	0.801	0.81
57_L	62_P	0.800	0.81
308_I	311_W	0.798	0.81
296_L	300_T	0.798	0.81
294_S	298_N	0.797	0.81
314_Q	317_E	0.796	0.81
373_M	377_A	0.791	0.80
49_K	52_L	0.790	0.80
344_D	353_A	0.790	0.80
54_W	57_L	0.789	0.80
335_W	352_L	0.788	0.80
371_A	378_P	0.787	0.80
352_L	364_R	0.786	0.80
563_I	606_I	0.784	0.80
501_T	509_G	0.784	0.80
345_D	352_L	0.784	0.80
406_E	410_D	0.783	0.80
556_Y	563_I	0.781	0.80
293_V	298_N	0.781	0.80
414_L	420_V	0.781	0.80
361_S	364_R	0.780	0.80
78_Q	82_H	0.780	0.80
301_A	311_W	0.779	0.79
50_R	57_L	0.777	0.79
350_R	361_S	0.777	0.79
381_I	384_L	0.777	0.79
132_I	135_A	0.777	0.79
368_G	373_M	0.774	0.79
120_L	139_L	0.773	0.79
95_M	98_I	0.771	0.79
359_W	366_H	0.770	0.79
229_R	440_Q	0.770	0.79
501_T	598_K	0.770	0.79
384_L	392_M	0.769	0.79
561_E	587_L	0.768	0.78
407_N	414_L	0.768	0.78
85_D	88_W	0.768	0.78
336_S	346_E	0.767	0.78
45_A	51_G	0.767	0.78
603_D	655_H	0.766	0.78
445_Q	448_A	0.766	0.78
550_L	556_Y	0.763	0.78
362_L	365_M	0.761	0.78
488_E	491_G	0.761	0.78
53_V	59_F	0.758	0.78
411_F	422_L	0.756	0.77
56_E	59_F	0.756	0.77
128_V	135_A	0.756	0.77
358_R	363_M	0.755	0.77
390_K	394_P	0.755	0.77
106_Q	110_I	0.754	0.77
357_D	365_M	0.753	0.77
340_G	346_E	0.751	0.77
297_E	301_A	0.750	0.77
297_E	303_R	0.749	0.77
114_T	132_I	0.748	0.77
60_V	65_K	0.748	0.77
340_G	350_R	0.747	0.77
360_V	373_M	0.745	0.76
395_L	401_G	0.745	0.76
231_G	267_T	0.744	0.76
228_A	260_R	0.743	0.76
404_K	413_G	0.741	0.76
407_N	410_D	0.741	0.76
338_P	341_N	0.737	0.76
67_V	72_T	0.735	0.75
45_A	48_C	0.734	0.75
355_R	359_W	0.733	0.75
229_R	647_Y	0.733	0.75
313_K	316_S	0.733	0.75
293_V	299_D	0.732	0.75
471_A	645_L	0.731	0.75
305_E	316_S	0.729	0.75
66_V	72_T	0.728	0.75
611_Q	661_F	0.727	0.75
46_I	54_W	0.727	0.75
231_G	266_H	0.727	0.75
392_M	407_N	0.726	0.74
217_G	220_S	0.725	0.74
398_A	402_A	0.723	0.74
228_A	440_Q	0.722	0.74
59_F	63_D	0.722	0.74
226_L	465_V	0.722	0.74
544_S	547_D	0.719	0.74
131_Q	140_P	0.719	0.74
56_E	63_D	0.718	0.74
413_G	553_L	0.718	0.74
50_R	56_E	0.717	0.74
286_G	300_T	0.717	0.74
65_K	69_L	0.716	0.73
66_V	71_G	0.716	0.73
343_W	350_R	0.715	0.73
597_S	602_A	0.715	0.73
342_F	345_D	0.715	0.73
340_G	347_K	0.713	0.73
348_L	355_R	0.712	0.73
396_L	408_A	0.711	0.73
436_V	464_A	0.711	0.73
357_D	360_V	0.711	0.73
205_V	225_V	0.707	0.73
342_F	348_L	0.706	0.72
51_G	58_E	0.704	0.72
156_W	166_I	0.704	0.72
597_S	605_V	0.703	0.72
367_G	371_A	0.703	0.72
377_A	380_E	0.702	0.72
440_Q	600_Q	0.701	0.72
304_H	309_A	0.699	0.72
403_L	406_E	0.699	0.72
360_V	369_A	0.697	0.71
356_L	361_S	0.696	0.71
368_G	372_E	0.695	0.71
568_R	645_L	0.695	0.71
504_F	512_A	0.693	0.71
349_Q	354_S	0.692	0.71
481_S	485_A	0.692	0.71
301_A	305_E	0.692	0.71
303_R	308_I	0.691	0.71
215_L	603_D	0.691	0.71
609_G	662_N	0.691	0.71
335_W	344_D	0.689	0.71
392_M	395_L	0.688	0.70
88_W	92_S	0.687	0.70
66_V	80_F	0.685	0.70
345_D	355_R	0.685	0.70
216_A	439_F	0.685	0.70
414_L	424_K	0.685	0.70
374_I	380_E	0.682	0.70
357_D	366_H	0.682	0.70
155_A	163_L	0.682	0.70
403_L	408_A	0.678	0.69
247_L	278_L	0.677	0.69
133_R	141_L	0.677	0.69
356_L	364_R	0.676	0.69
73_E	86_A	0.676	0.69
440_Q	472_I	0.676	0.69
218_A	568_R	0.674	0.69
509_G	523_L	0.674	0.69
81_Y	86_A	0.672	0.69
61_L	67_V	0.670	0.68
356_L	359_W	0.670	0.68
359_W	378_P	0.670	0.68
248_A	512_A	0.669	0.68
57_L	60_V	0.669	0.68
249_F	253_A	0.669	0.68
307_F	315_C	0.669	0.68
410_D	415_I	0.668	0.68
227_V	257_M	0.667	0.68
75_G	81_Y	0.667	0.68
78_Q	81_Y	0.666	0.68
482_L	485_A	0.666	0.68
47_H	51_G	0.666	0.68
217_G	469_W	0.665	0.68
131_Q	163_L	0.664	0.68
198_N	206_V	0.664	0.68
585_P	588_Q	0.664	0.68
64_E	68_R	0.664	0.68
365_M	565_I	0.663	0.68
438_E	470_Q	0.661	0.67
69_L	77_T	0.661	0.67
72_T	80_F	0.661	0.67
363_M	370_Q	0.661	0.67
229_R	433_H	0.658	0.67
116_E	133_R	0.655	0.67
484_T	612_E	0.655	0.67
427_F	430_P	0.655	0.67
373_M	379_E	0.655	0.67
409_V	412_S	0.654	0.67
116_E	135_A	0.654	0.67
72_T	77_T	0.653	0.66
59_F	65_K	0.651	0.66
131_Q	134_Q	0.650	0.66
154_E	158_K	0.649	0.66
253_A	256_E	0.647	0.66
542_D	572_M	0.646	0.66
133_R	235_A	0.646	0.66
372_E	377_A	0.645	0.66
362_L	366_H	0.645	0.66
382_R	387_K	0.644	0.65
54_W	61_L	0.643	0.65
374_I	381_I	0.642	0.65
451_A	454_R	0.642	0.65
548_A	660_L	0.642	0.65
249_F	257_M	0.641	0.65
103_L	110_I	0.641	0.65
57_L	66_V	0.641	0.65
73_E	81_Y	0.640	0.65
365_M	368_G	0.639	0.65
355_R	360_V	0.638	0.65
612_E	660_L	0.637	0.65
605_V	657_V	0.637	0.65
538_V	661_F	0.635	0.64
281_H	284_Q	0.634	0.64
52_L	55_G	0.634	0.64
440_Q	602_A	0.633	0.64
59_F	64_E	0.633	0.64
344_D	352_L	0.633	0.64
350_R	353_A	0.632	0.64
197_L	228_A	0.632	0.64
63_D	68_R	0.632	0.64
49_K	80_F	0.625	0.63
77_T	88_W	0.624	0.63
343_W	355_R	0.623	0.63
215_L	254_A	0.623	0.63
52_L	60_V	0.618	0.62
436_V	450_L	0.618	0.62
406_E	422_L	0.618	0.62
375_A	382_R	0.618	0.62
408_A	418_A	0.616	0.62
250_G	258_D	0.616	0.62
407_N	411_F	0.616	0.62
229_R	598_K	0.616	0.62
339_E	344_D	0.615	0.62
304_H	314_Q	0.615	0.62
565_I	584_W	0.615	0.62
356_L	363_M	0.614	0.62
485_A	488_E	0.613	0.62
357_D	361_S	0.611	0.61
57_L	61_L	0.610	0.61
273_R	281_H	0.608	0.61
75_G	85_D	0.607	0.61
336_S	351_R	0.607	0.61
413_G	420_V	0.605	0.61
216_A	249_F	0.605	0.61
404_K	408_A	0.605	0.61
567_A	572_M	0.604	0.60
356_L	374_I	0.603	0.60
48_C	53_V	0.603	0.60
121_T	125_T	0.602	0.60
70_H	77_T	0.598	0.60
410_D	413_G	0.598	0.60
308_I	313_K	0.596	0.59
411_F	419_I	0.595	0.59
115_G	137_S	0.595	0.59
339_E	346_E	0.594	0.59
495_R	513_N	0.594	0.59
68_R	74_W	0.593	0.59
338_P	348_L	0.593	0.59
234_L	463_F	0.593	0.59
215_L	495_R	0.593	0.59
135_A	175_Q	0.592	0.59
547_D	579_K	0.592	0.59
114_T	141_L	0.592	0.59
228_A	246_L	0.591	0.59
47_H	62_P	0.591	0.59
551_D	555_G	0.591	0.59
69_L	74_W	0.591	0.59
48_C	58_E	0.591	0.59
539_T	660_L	0.589	0.59
480_M	484_T	0.588	0.58
65_K	68_R	0.588	0.58
341_N	351_R	0.587	0.58
140_P	177_Y	0.587	0.58
599_G	652_R	0.586	0.58
81_Y	85_D	0.586	0.58
53_V	58_E	0.585	0.58
97_E	115_G	0.585	0.58
375_A	380_E	0.584	0.58
395_L	421_I	0.584	0.58
374_I	378_P	0.584	0.58
363_M	366_H	0.583	0.58
248_A	254_A	0.583	0.58
545_Q	608_V	0.582	0.58
594_I	646_M	0.581	0.58
49_K	57_L	0.581	0.58
175_Q	182_L	0.580	0.57
336_S	345_D	0.579	0.57
197_L	202_A	0.578	0.57
312_R	315_C	0.578	0.57
357_D	362_L	0.578	0.57
184_E	188_F	0.577	0.57
70_H	74_W	0.577	0.57
547_D	558_K	0.577	0.57
354_S	359_W	0.577	0.57
65_K	78_Q	0.576	0.57
341_N	346_E	0.574	0.57
384_L	390_K	0.573	0.57
337_V	355_R	0.573	0.57
351_R	354_S	0.573	0.57
406_E	418_A	0.571	0.56
485_A	490_F	0.570	0.56
535_K	538_V	0.570	0.56
168_S	171_L	0.570	0.56
337_V	340_G	0.569	0.56
250_G	257_M	0.567	0.56
139_L	150_D	0.567	0.56
72_T	75_G	0.566	0.56
198_N	228_A	0.566	0.56
231_G	250_G	0.565	0.55
552_K	658_W	0.565	0.55
68_R	75_G	0.564	0.55
202_A	228_A	0.564	0.55
450_L	454_R	0.564	0.55
511_V	653_A	0.564	0.55
117_N	143_V	0.564	0.55
341_N	352_L	0.563	0.55
565_I	591_F	0.563	0.55
194_S	231_G	0.562	0.55
365_M	372_E	0.562	0.55
410_D	425_G	0.560	0.55
506_S	532_N	0.560	0.55
299_D	307_F	0.560	0.55
343_W	346_E	0.560	0.55
484_T	487_H	0.559	0.55
569_Y	593_T	0.559	0.55
228_A	435_L	0.558	0.55
358_R	390_K	0.558	0.55
533_G	537_A	0.556	0.54
250_G	256_E	0.556	0.54
384_L	388_R	0.553	0.54
49_K	55_G	0.552	0.54
380_E	385_F	0.551	0.54
577_L	591_F	0.551	0.54
363_M	368_G	0.550	0.53
47_H	61_L	0.549	0.53
450_L	462_L	0.548	0.53
542_D	612_E	0.548	0.53
412_S	425_G	0.547	0.53
247_L	596_A	0.545	0.53
196_P	206_V	0.544	0.53
198_N	202_A	0.544	0.53
227_V	440_Q	0.543	0.53
178_T	182_L	0.543	0.53
405_A	421_I	0.543	0.53
296_L	301_A	0.542	0.52
472_I	598_K	0.541	0.52
50_R	58_E	0.539	0.52
127_G	133_R	0.539	0.52
72_T	76_E	0.539	0.52
49_K	60_V	0.538	0.52
49_K	62_P	0.538	0.52
342_F	349_Q	0.537	0.52
264_R	531_T	0.536	0.52
380_E	386_S	0.536	0.52
249_F	441_D	0.536	0.52
650_L	659_A	0.535	0.52
294_S	558_K	0.535	0.52
56_E	69_L	0.533	0.51
434_I	462_L	0.533	0.51
553_L	556_Y	0.533	0.51
211_S	460_T	0.532	0.51
543_E	550_L	0.531	0.51
78_Q	85_D	0.529	0.51
67_V	83_H	0.528	0.51
156_W	161_A	0.528	0.51
130_Q	141_L	0.528	0.51
388_R	394_P	0.527	0.50
45_A	49_K	0.526	0.50
167_E	174_N	0.526	0.50
71_G	76_E	0.526	0.50
98_I	101_G	0.525	0.50
337_V	345_D	0.525	0.50
541_L	545_Q	0.525	0.50
153_R	163_L	0.525	0.50
384_L	565_I	0.524	0.50
144_N	148_E	0.523	0.50
540_L	664_E	0.522	0.50
69_L	81_Y	0.520	0.50
336_S	342_F	0.520	0.50
211_S	462_L	0.520	0.50
413_G	421_I	0.520	0.50
411_F	417_Q	0.520	0.50
200_A	499_D	0.519	0.49
270_I	651_T	0.519	0.49
505_N	533_G	0.519	0.49
409_V	416_H	0.519	0.49
298_N	307_F	0.518	0.49
74_W	77_T	0.518	0.49
226_L	260_R	0.517	0.49
483_T	644_R	0.517	0.49
477_G	480_M	0.516	0.49
228_A	600_Q	0.516	0.49
137_S	140_P	0.516	0.49
200_A	508_I	0.516	0.49
343_W	356_L	0.516	0.49
46_I	58_E	0.515	0.49
338_P	345_D	0.515	0.49
272_A	276_H	0.515	0.49
235_A	257_M	0.514	0.49
349_Q	356_L	0.513	0.49
63_D	91_W	0.513	0.49
198_N	600_Q	0.513	0.49
154_E	166_I	0.510	0.48
338_P	343_W	0.508	0.48
65_K	71_G	0.508	0.48
248_A	505_N	0.508	0.48
471_A	501_T	0.507	0.48
54_W	59_F	0.507	0.48
69_L	75_G	0.506	0.48
228_A	454_R	0.506	0.48
377_A	382_R	0.505	0.48
346_E	350_R	0.504	0.47
97_E	131_Q	0.503	0.47
433_H	463_F	0.502	0.47
59_F	66_V	0.502	0.47
60_V	70_H	0.502	0.47
343_W	347_K	0.501	0.47
478_A	484_T	0.500	0.47

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1pjrA	1	0.6447	100	0.466	Contact Map
4c2tA	1	0.6594	100	0.468	Contact Map
4b3fX	1	0.8041	100	0.48	Contact Map
1uaaA	2	0.636	100	0.492	Contact Map
4c2uA	1	0.655	100	0.494	Contact Map
3lfuA	1	0.6404	100	0.495	Contact Map
2xzlA	1	0.7924	100	0.499	Contact Map
4pj3A	1	0.886	100	0.503	Contact Map
2wjyA	1	0.8289	100	0.519	Contact Map
2gk6A	1	0.7734	100	0.527	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0152 seconds.