MURD - ECOLI - GREMLIN Contacts

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MURD - UDP-N-acetylmuramoylalanine--D-glutamate ligase

UniProt:	P14900	Sequences: MADYQGKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRMTPPGLDKLPEAVERHTGSLNDEWLMAADLIVASPGIALAHPSLSAAADAGIEIVGDIELFCREAQAPIVAITGSNGKSTVTTLVGEMAKAAGVNVGVGGNIGLPALMLLDDECELYVLELSSFQLETTSSLQAVAATILNVTEDHMDRYPFGLQQYRAAKLRIYENAKVCVVNADDALTMPIRGADERCVSFGVNMGDYHLNHQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALAALALADAAGLPRASSLKALTTFTGLPHRFEVVLEHNGVRWINDSKATNVGSTEAALNGLHVDGTLHLLLGGDGKSADFSPLARYLNGDNVRLYCFGRDGAQLAALRPEVAEQTETMEQAMRLLAPRVQPGDMVLLSPACASLDQFKNFEQRGNEFARLAKELG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10620
Length:	438 (385)
Sequences:	18231 (13629)
Seq/√Len:	694.6

ECOLI - MURD MURC MPL MURE MURF
BACSU - MURD MURC MURE MURF

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
176_T	279_L	3.530	1.00
231_F	275_A	2.747	1.00
129_A	296_T	2.683	1.00
386_E	397_L	2.623	1.00
32_P	44_L	2.573	1.00
397_L	401_R	2.562	1.00
106_P	173_V	2.555	1.00
286_P	289_S	2.548	1.00
277_L	290_S	2.511	1.00
306_V	314_R	2.491	1.00
174_A	279_L	2.462	1.00
176_T	275_A	2.414	1.00
388_T	397_L	2.410	1.00
191_G	194_Q	2.390	1.00
390_T	393_Q	2.384	1.00
126_M	276_A	2.306	1.00
126_M	280_A	2.242	1.00
129_A	293_A	2.235	1.00
238_Y	278_A	2.202	1.00
84_A	88_A	2.200	1.00
84_A	87_D	2.196	1.00
261_E	295_T	2.182	1.00
328_E	332_N	2.167	1.00
196_R	220_P	2.165	1.00
208_V	282_A	2.148	1.00
241_N	252_K	2.142	1.00
213_A	236_G	2.110	1.00
348_G	377_L	2.071	1.00
242_H	250_R	2.056	1.00
189_P	194_Q	2.027	1.00
173_V	207_K	1.992	1.00
397_L	400_P	1.980	1.00
262_M	273_A	1.975	1.00
129_A	292_K	1.949	1.00
130_A	289_S	1.937	1.00
250_R	259_V	1.884	1.00
366_R	401_R	1.860	1.00
402_V	408_V	1.853	1.00
123_V	276_A	1.850	1.00
339_T	406_D	1.840	1.00
125_E	296_T	1.838	1.00
109_A	172_A	1.832	1.00
366_R	386_E	1.828	1.00
132_V	153_E	1.817	1.00
108_V	283_A	1.815	1.00
342_L	365_V	1.773	1.00
196_R	217_L	1.752	1.00
61_E	64_M	1.749	1.00
341_H	401_R	1.747	1.00
258_N	291_L	1.744	1.00
181_T	325_G	1.737	1.00
109_A	159_L	1.727	1.00
281_D	287_R	1.707	1.00
123_V	279_L	1.695	1.00
233_V	267_Q	1.689	1.00
124_G	128_K	1.683	1.00
194_Q	197_A	1.682	1.00
306_V	316_I	1.675	1.00
273_A	294_L	1.672	1.00
240_L	274_L	1.668	1.00
203_Y	209_C	1.666	1.00
110_I	123_V	1.645	1.00
123_V	280_A	1.643	1.00
124_G	136_V	1.643	1.00
47_L	70_V	1.640	1.00
309_E	314_R	1.591	1.00
130_A	285_L	1.573	1.00
174_A	283_A	1.562	1.00
329_A	332_N	1.562	1.00
106_P	154_L	1.551	1.00
82_L	86_A	1.535	1.00
175_A	202_I	1.532	1.00
134_V	137_G	1.511	1.00
127_A	156_V	1.511	1.00
53_R	57_S	1.506	1.00
280_A	290_S	1.506	1.00
145_L	149_D	1.502	1.00
34_V	39_M	1.489	1.00
198_A	201_R	1.479	1.00
248_W	261_E	1.479	1.00
208_V	227_R	1.476	1.00
213_A	230_S	1.475	1.00
267_Q	332_N	1.466	1.00
248_W	259_V	1.464	1.00
388_T	393_Q	1.463	1.00
108_V	123_V	1.460	1.00
208_V	229_V	1.459	1.00
291_L	295_T	1.456	1.00
368_Y	401_R	1.455	1.00
125_E	293_A	1.454	1.00
60_D	64_M	1.448	1.00
114_N	323_N	1.447	1.00
249_L	273_A	1.436	1.00
83_S	86_A	1.434	1.00
161_S	188_Y	1.424	1.00
238_Y	281_D	1.410	1.00
136_V	139_N	1.408	1.00
263_K	298_T	1.407	1.00
127_A	283_A	1.396	1.00
34_V	40_T	1.391	1.00
210_V	282_A	1.385	1.00
165_E	168_S	1.383	1.00
315_W	399_A	1.381	1.00
154_L	283_A	1.379	1.00
122_L	264_L	1.379	1.00
289_S	292_K	1.373	1.00
253_G	256_V	1.365	1.00
107_I	170_L	1.362	1.00
118_T	269_N	1.357	1.00
230_S	237_D	1.339	1.00
380_L	384_V	1.337	1.00
252_K	257_L	1.332	1.00
313_V	402_V	1.332	1.00
211_V	228_C	1.324	1.00
251_V	277_L	1.312	1.00
174_A	282_A	1.308	1.00
280_A	285_L	1.302	1.00
180_V	196_R	1.297	1.00
292_K	296_T	1.295	1.00
119_V	178_L	1.295	1.00
341_H	366_R	1.289	1.00
374_G	377_L	1.283	1.00
369_C	378_A	1.256	1.00
177_I	180_V	1.253	1.00
110_I	120_T	1.250	1.00
106_P	153_E	1.249	1.00
355_P	359_Y	1.249	1.00
171_Q	207_K	1.247	1.00
211_V	230_S	1.240	1.00
339_T	365_V	1.239	1.00
354_S	358_R	1.239	1.00
339_T	366_R	1.234	1.00
258_N	287_R	1.232	1.00
239_H	252_K	1.232	1.00
236_G	239_H	1.229	1.00
122_L	297_F	1.226	1.00
353_F	373_D	1.226	1.00
393_Q	396_R	1.222	1.00
368_Y	397_L	1.215	1.00
200_L	221_I	1.212	1.00
250_R	257_L	1.211	1.00
267_Q	271_T	1.203	1.00
41_P	44_L	1.202	1.00
212_N	271_T	1.201	1.00
306_V	309_E	1.198	1.00
227_R	282_A	1.193	1.00
304_F	334_L	1.192	1.00
133_N	153_E	1.191	1.00
312_G	404_P	1.186	1.00
246_E	261_E	1.182	1.00
117_S	300_L	1.182	1.00
269_N	272_N	1.181	1.00
174_A	210_V	1.181	1.00
301_P	305_E	1.178	1.00
182_E	185_M	1.178	1.00
328_E	359_Y	1.176	1.00
182_E	352_D	1.166	1.00
370_F	394_A	1.163	1.00
343_L	370_F	1.161	1.00
327_T	411_S	1.159	1.00
356_L	359_Y	1.159	1.00
123_V	176_T	1.155	1.00
34_V	44_L	1.148	1.00
217_L	220_P	1.146	1.00
359_Y	363_D	1.145	1.00
135_G	147_L	1.144	1.00
347_D	372_R	1.143	1.00
134_V	139_N	1.138	1.00
193_Q	197_A	1.135	1.00
233_V	271_T	1.132	1.00
211_V	218_T	1.130	1.00
127_A	285_L	1.129	1.00
396_R	400_P	1.128	1.00
229_V	282_A	1.126	1.00
229_V	278_A	1.126	1.00
292_K	295_T	1.123	1.00
113_S	183_D	1.122	1.00
334_L	340_L	1.120	1.00
253_G	281_D	1.118	1.00
304_F	316_I	1.104	1.00
159_L	167_T	1.102	1.00
97_E	101_R	1.101	1.00
240_L	270_Y	1.091	1.00
249_L	270_Y	1.085	1.00
210_V	278_A	1.083	1.00
201_R	204_E	1.082	1.00
63_L	81_S	1.073	1.00
211_V	222_R	1.068	1.00
305_E	317_N	1.068	1.00
58_L	62_W	1.068	1.00
44_L	48_P	1.068	1.00
177_I	203_Y	1.065	1.00
328_E	363_D	1.064	1.00
288_A	292_K	1.064	1.00
182_E	192_L	1.063	1.00
339_T	403_Q	1.055	1.00
108_V	279_L	1.055	1.00
197_A	201_R	1.054	1.00
91_E	95_D	1.045	1.00
192_L	217_L	1.042	1.00
213_A	219_M	1.042	1.00
132_V	154_L	1.042	1.00
88_A	91_E	1.040	1.00
393_Q	397_L	1.037	1.00
220_P	223_G	1.032	1.00
234_N	267_Q	1.032	1.00
166_T	169_S	1.031	1.00
122_L	273_A	1.030	1.00
126_M	290_S	1.030	1.00
164_L	198_A	1.029	1.00
338_G	407_M	1.029	1.00
403_Q	406_D	1.024	1.00
214_D	271_T	1.023	1.00
127_A	154_L	1.019	1.00
126_M	293_A	1.018	1.00
241_N	257_L	1.015	1.00
341_H	368_Y	1.014	1.00
368_Y	394_A	1.013	1.00
241_N	250_R	1.011	1.00
72_S	89_G	1.008	1.00
322_T	327_T	1.006	1.00
178_L	275_A	1.005	1.00
392_E	396_R	1.005	1.00
196_R	200_L	1.004	1.00
194_Q	198_A	1.002	1.00
309_E	313_V	0.995	1.00
39_M	47_L	0.992	1.00
130_A	293_A	0.991	1.00
201_R	205_N	0.987	1.00
309_E	312_G	0.985	1.00
375_A	379_A	0.984	1.00
380_L	383_E	0.982	1.00
177_I	221_I	0.981	1.00
125_E	128_K	0.979	1.00
124_G	134_V	0.977	1.00
341_H	406_D	0.976	1.00
53_R	58_L	0.975	1.00
381_R	384_V	0.973	1.00
114_N	325_G	0.971	1.00
379_A	383_E	0.969	1.00
174_A	208_V	0.966	1.00
285_L	289_S	0.958	1.00
342_L	364_N	0.957	1.00
59_N	69_I	0.955	1.00
106_P	283_A	0.954	1.00
140_I	143_P	0.948	1.00
86_A	92_I	0.944	1.00
369_C	387_Q	0.941	1.00
287_R	291_L	0.939	1.00
59_N	62_W	0.939	1.00
107_I	155_Y	0.930	1.00
330_A	409_L	0.929	1.00
230_S	236_G	0.929	1.00
45_D	68_L	0.928	1.00
375_A	387_Q	0.924	1.00
45_D	48_P	0.924	1.00
313_V	405_G	0.924	1.00
342_L	411_S	0.920	1.00
104_Q	145_L	0.920	1.00
129_A	289_S	0.920	1.00
193_Q	217_L	0.917	1.00
125_E	297_F	0.908	1.00
327_T	344_L	0.901	1.00
379_A	382_P	0.894	1.00
93_V	101_R	0.893	1.00
130_A	286_P	0.890	1.00
386_E	401_R	0.889	1.00
232_G	271_T	0.884	1.00
94_G	169_S	0.883	1.00
104_Q	148_L	0.883	1.00
83_S	87_D	0.881	1.00
145_L	148_L	0.881	1.00
162_F	187_R	0.877	1.00
316_I	334_L	0.873	1.00
281_D	290_S	0.872	1.00
239_H	242_H	0.867	1.00
44_L	47_L	0.865	1.00
389_E	393_Q	0.865	1.00
37_T	40_T	0.864	1.00
183_D	323_N	0.863	1.00
58_L	61_E	0.862	1.00
243_Q	248_W	0.862	1.00
325_G	329_A	0.860	1.00
86_A	89_G	0.860	1.00
164_L	194_Q	0.855	1.00
97_E	100_C	0.854	1.00
304_F	333_G	0.852	1.00
398_L	402_V	0.852	1.00
277_L	281_D	0.851	1.00
111_T	199_K	0.851	1.00
200_L	224_A	0.850	1.00
359_Y	362_G	0.849	1.00
346_G	374_G	0.848	1.00
200_L	204_E	0.846	1.00
121_T	140_I	0.846	1.00
40_T	44_L	0.846	1.00
63_L	69_I	0.846	1.00
43_G	47_L	0.844	1.00
357_A	361_N	0.842	1.00
358_R	362_G	0.842	1.00
302_H	317_N	0.842	1.00
378_A	387_Q	0.841	1.00
279_L	283_A	0.840	1.00
197_A	224_A	0.840	1.00
45_D	70_V	0.839	1.00
182_E	356_L	0.838	1.00
388_T	394_A	0.837	1.00
125_E	129_A	0.837	1.00
394_A	398_L	0.836	1.00
216_A	220_P	0.836	1.00
353_F	357_A	0.835	1.00
372_R	389_E	0.834	1.00
214_D	232_G	0.833	1.00
109_A	202_I	0.831	1.00
215_D	271_T	0.830	1.00
193_Q	196_R	0.822	1.00
62_W	66_A	0.819	1.00
378_A	382_P	0.818	1.00
249_L	260_K	0.814	1.00
119_V	275_A	0.812	1.00
77_L	86_A	0.812	1.00
243_Q	246_E	0.803	1.00
192_L	196_R	0.798	1.00
130_A	280_A	0.797	1.00
33_R	66_A	0.796	1.00
352_D	355_P	0.794	1.00
212_N	215_D	0.791	1.00
214_D	233_V	0.791	1.00
233_V	240_L	0.789	1.00
209_C	226_E	0.787	1.00
250_R	253_G	0.786	1.00
96_I	99_F	0.786	1.00
260_K	291_L	0.786	1.00
314_R	407_M	0.779	1.00
336_V	407_M	0.775	1.00
258_N	288_A	0.774	1.00
120_T	136_V	0.773	1.00
97_E	169_S	0.773	1.00
95_D	98_L	0.768	1.00
119_V	276_A	0.766	1.00
59_N	63_L	0.764	1.00
94_G	97_E	0.763	1.00
159_L	172_A	0.763	1.00
149_D	152_C	0.759	1.00
197_A	200_L	0.757	1.00
39_M	44_L	0.757	1.00
164_L	197_A	0.752	1.00
364_N	367_L	0.752	1.00
50_A	53_R	0.751	1.00
277_L	287_R	0.747	1.00
91_E	101_R	0.744	1.00
395_M	399_A	0.742	1.00
213_A	218_T	0.741	1.00
219_M	223_G	0.738	1.00
181_T	192_L	0.738	1.00
331_L	342_L	0.737	1.00
107_I	157_L	0.737	1.00
121_T	300_L	0.736	1.00
316_I	407_M	0.736	1.00
238_Y	253_G	0.733	1.00
31_T	43_G	0.732	1.00
188_Y	198_A	0.731	1.00
219_M	230_S	0.728	1.00
285_L	290_S	0.728	1.00
93_V	97_E	0.727	1.00
56_G	59_N	0.727	1.00
88_A	92_I	0.725	1.00
338_G	406_D	0.724	1.00
264_L	297_F	0.723	1.00
335_H	340_L	0.720	1.00
321_A	411_S	0.717	1.00
312_G	405_G	0.717	1.00
373_D	376_Q	0.716	1.00
232_G	239_H	0.716	1.00
346_G	373_D	0.715	1.00
210_V	279_L	0.714	1.00
368_Y	388_T	0.712	1.00
124_G	135_G	0.709	1.00
37_T	58_L	0.708	1.00
124_G	156_V	0.705	1.00
290_S	293_A	0.703	1.00
48_P	59_N	0.703	1.00
354_S	376_Q	0.703	1.00
168_S	204_E	0.700	1.00
165_E	198_A	0.700	1.00
93_V	98_L	0.700	1.00
193_Q	220_P	0.699	1.00
64_M	88_A	0.698	1.00
192_L	195_Y	0.698	1.00
268_H	329_A	0.697	1.00
358_R	384_V	0.697	1.00
164_L	187_R	0.697	1.00
345_G	412_P	0.695	1.00
133_N	152_C	0.695	1.00
120_T	156_V	0.694	1.00
182_E	325_G	0.694	1.00
391_M	395_M	0.694	1.00
89_G	92_I	0.693	1.00
232_G	236_G	0.692	1.00
144_A	147_L	0.691	1.00
161_S	198_A	0.691	1.00
212_N	231_F	0.690	1.00
222_R	230_S	0.689	1.00
126_M	130_A	0.685	1.00
45_D	49_E	0.683	1.00
243_Q	261_E	0.682	1.00
341_H	402_V	0.681	1.00
180_V	192_L	0.674	1.00
178_L	231_F	0.673	1.00
343_L	408_V	0.673	1.00
229_V	238_Y	0.672	1.00
82_L	85_A	0.670	1.00
343_L	410_L	0.669	1.00
123_V	156_V	0.667	1.00
314_R	338_G	0.666	1.00
60_D	63_L	0.666	1.00
375_A	378_A	0.666	1.00
343_L	398_L	0.665	1.00
58_L	63_L	0.661	1.00
213_A	232_G	0.661	1.00
177_I	196_R	0.661	1.00
311_N	404_P	0.659	1.00
233_V	274_L	0.655	1.00
267_Q	270_Y	0.655	1.00
321_A	330_A	0.655	1.00
334_L	409_L	0.653	1.00
321_A	326_S	0.653	1.00
47_L	89_G	0.651	1.00
175_A	206_A	0.643	1.00
355_P	358_R	0.636	1.00
43_G	46_K	0.635	1.00
93_V	96_I	0.634	1.00
108_V	127_A	0.633	1.00
128_K	133_N	0.633	1.00
110_I	176_T	0.632	1.00
163_Q	187_R	0.632	1.00
121_T	125_E	0.631	1.00
315_W	408_V	0.631	1.00
31_T	52_E	0.629	1.00
288_A	291_L	0.628	1.00
372_R	375_A	0.628	1.00
270_Y	274_L	0.623	1.00
264_L	269_N	0.622	1.00
330_A	411_S	0.621	1.00
277_L	294_L	0.619	1.00
328_E	360_L	0.618	1.00
71_A	82_L	0.618	1.00
335_H	363_D	0.618	1.00
310_H	313_V	0.617	1.00
252_K	256_V	0.616	1.00
122_L	276_A	0.616	1.00
134_V	148_L	0.616	1.00
185_M	189_P	0.616	1.00
54_H	62_W	0.614	1.00
105_A	148_L	0.614	1.00
35_M	53_R	0.614	1.00
266_G	269_N	0.613	1.00
341_H	398_L	0.612	1.00
114_N	326_S	0.611	1.00
356_L	360_L	0.610	1.00
353_F	356_L	0.610	1.00
73_P	76_A	0.609	1.00
348_G	351_A	0.609	1.00
196_R	221_I	0.605	1.00
219_M	222_R	0.605	1.00
274_L	278_A	0.605	1.00
278_A	282_A	0.604	1.00
30_V	45_D	0.601	1.00
247_T	270_Y	0.601	1.00
332_N	363_D	0.599	1.00
114_N	181_T	0.598	1.00
323_N	326_S	0.597	1.00
370_F	391_M	0.597	1.00
105_A	155_Y	0.597	1.00
210_V	229_V	0.597	1.00
343_L	394_A	0.596	1.00
304_F	330_A	0.594	1.00
98_L	171_Q	0.594	1.00
68_L	93_V	0.593	1.00
133_N	151_E	0.593	1.00
81_S	84_A	0.593	1.00
218_T	222_R	0.592	1.00
79_H	82_L	0.590	1.00
88_A	93_V	0.589	1.00
331_L	364_N	0.588	1.00
36_D	39_M	0.588	1.00
127_A	280_A	0.588	1.00
161_S	167_T	0.583	1.00
185_M	191_G	0.583	1.00
242_H	259_V	0.583	1.00
108_V	154_L	0.579	1.00
308_L	314_R	0.578	1.00
40_T	66_A	0.576	1.00
358_R	380_L	0.576	1.00
337_D	407_M	0.575	1.00
369_C	385_A	0.572	1.00
173_V	206_A	0.572	1.00
164_L	201_R	0.571	1.00
118_T	122_L	0.570	1.00
90_I	94_G	0.570	1.00
144_A	148_L	0.570	1.00
332_N	364_N	0.569	1.00
98_L	101_R	0.569	1.00
338_G	405_G	0.568	1.00
55_T	58_L	0.568	1.00
171_Q	205_N	0.566	1.00
360_L	364_N	0.565	1.00
85_A	88_A	0.564	1.00
255_K	258_N	0.563	1.00
69_I	81_S	0.563	1.00
339_T	367_L	0.562	1.00
43_G	55_T	0.560	1.00
95_D	100_C	0.559	1.00
57_S	73_P	0.559	1.00
262_M	294_L	0.557	1.00
348_G	353_F	0.556	1.00
287_R	290_S	0.556	1.00
218_T	221_I	0.556	1.00
60_D	84_A	0.556	1.00
365_V	403_Q	0.554	1.00
56_G	72_S	0.554	1.00
279_L	282_A	0.554	1.00
124_G	143_P	0.554	1.00
92_I	99_F	0.552	1.00
277_L	291_L	0.551	1.00
235_M	239_H	0.549	1.00
134_V	138_G	0.548	1.00
110_I	119_V	0.547	1.00
232_G	235_M	0.545	1.00
162_F	186_D	0.544	1.00
62_W	65_A	0.543	1.00
46_K	49_E	0.543	1.00
126_M	285_L	0.542	1.00
340_L	365_V	0.541	1.00
167_T	201_R	0.541	1.00
164_L	188_Y	0.540	1.00
121_T	301_P	0.539	1.00
346_G	376_Q	0.537	1.00
206_A	226_E	0.537	1.00
202_I	205_N	0.536	1.00
134_V	152_C	0.535	1.00
32_P	41_P	0.534	1.00
74_G	85_A	0.531	1.00
89_G	93_V	0.529	1.00
103_A	171_Q	0.528	1.00
334_L	407_M	0.527	1.00
253_G	287_R	0.527	1.00
103_A	106_P	0.527	1.00
118_T	297_F	0.524	1.00
315_W	410_L	0.523	1.00
317_N	410_L	0.523	1.00
228_C	232_G	0.522	1.00
327_T	360_L	0.520	1.00
289_S	293_A	0.520	1.00
78_A	83_S	0.519	1.00
307_V	317_N	0.519	1.00
260_K	273_A	0.518	1.00
74_G	77_L	0.517	1.00
374_G	387_Q	0.517	1.00
162_F	166_T	0.517	1.00
72_S	75_I	0.517	1.00
348_G	376_Q	0.517	1.00
357_A	360_L	0.516	0.99
365_V	406_D	0.515	0.99
57_S	61_E	0.513	0.99
165_E	169_S	0.512	0.99
80_P	84_A	0.511	0.99
173_V	208_V	0.510	0.99
65_A	88_A	0.508	0.99
147_L	155_Y	0.507	0.99
102_E	171_Q	0.506	0.99
244_Q	247_T	0.506	0.99
165_E	187_R	0.505	0.99
236_G	240_L	0.505	0.99
353_F	414_C	0.505	0.99
396_R	399_A	0.504	0.99
213_A	234_N	0.501	0.99
114_N	179_N	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2x5oA	1	0.9954	100	0.146	Contact Map
3lk7A	1	0.984	100	0.201	Contact Map
4bucA	1	0.9406	100	0.236	Contact Map
3hn7A	1	0.9566	100	0.303	Contact Map
1p3dA	1	0.9635	100	0.309	Contact Map
4hv4A	1	0.9635	100	0.32	Contact Map
4c12A	2	0.9726	100	0.328	Contact Map
1j6uA	1	0.9201	100	0.331	Contact Map
4qdiA	1	0.9452	100	0.338	Contact Map
4cvkA	1	0.9247	100	0.339	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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