ZRAS - ECOLI - GREMLIN Contacts

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ZRAS - Sensor protein ZraS

UniProt:	P14377	Sequences: MRFMQRSKDSLAKWLSAILPVVIVGLVGLFAVTVIRDYGRASEADRQALLEKGNVLIRALESGSRVGMGMRMHHVQQQALLEEMAGQPGVLWFAVTDAQGIIILHSDPDKVGRALYSPDEMQKLKPEENSRWRLLGKTETTPALEVYRLFQPMSAPWRHGMHNMPRCNGKAVPQVDAQQAIFIAVDASDLVATQSGEKRNTLIILFALATVLLASVLSFFWYRRYLRSRQLLQDEMKRKEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQLAQVMAKEADRLNRVVSELLELVKPTHLALQAVDLNTLINHSLQLVSQDANSREIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGKGIAADQLDAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASQEGKGSTFTLWLPVNITRKDPQG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10008
Length:	465 (410)
Sequences:	43946 (39833)
Seq/√Len:	1967.2

ECOLI - ZRAS BARA ARCB ATOS RCSD CREC RCSC GLRK TORS PHOQ DCUS EVGS ENVZ DPIB CUSS BAES PHOR QSEC CPXA RSTB YEDV KDPD NARX NTRB NARQ BASS YPDA UHPB
BACSU - KINE YYCG KINA KIND PHOR RESE DCTS CITS YCLK MALK KINC YVRG CSSS YKOH KINB YRKQ LYTS YVCQ YCBM DEGS BCES GLNK YXDK COMP YESM YHCY NATK LIAS YDFH
HALSA - Q9HQ16 O51970 Q9HRE4 Q9HR10 Q9HQG5 Q9HRG1 Q9HNA6 Q9HNM2 Q9HQB9 Q9HQ15 Q9HQE9 BAT

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
315_V	352_A	3.818	1.00
394_T	449_T	3.809	1.00
395_D	399_G	3.561	1.00
439_Q	451_T	3.462	1.00
428_H	432_E	3.308	1.00
392_S	449_T	3.271	1.00
388_G	453_W	3.228	1.00
267_A	287_M	3.118	1.00
352_A	434_H	2.924	1.00
381_T	392_S	2.881	1.00
340_R	379_S	2.863	1.00
340_R	377_V	2.829	1.00
314_A	351_Q	2.815	1.00
390_K	453_W	2.814	1.00
405_L	442_S	2.804	1.00
392_S	451_T	2.801	1.00
372_I	396_S	2.798	1.00
271_A	288_A	2.742	1.00
401_A	404_Q	2.736	1.00
264_K	292_D	2.662	1.00
383_S	390_K	2.623	1.00
379_S	394_T	2.610	1.00
390_K	451_T	2.609	1.00
342_T	381_T	2.577	1.00
271_A	285_Q	2.515	1.00
443_Q	446_K	2.447	1.00
377_V	396_S	2.440	1.00
381_T	394_T	2.430	1.00
440_V	450_F	2.429	1.00
405_L	440_V	2.424	1.00
383_S	392_S	2.394	1.00
427_V	438_I	2.391	1.00
264_K	291_A	2.389	1.00
441_A	449_T	2.341	1.00
360_V	431_V	2.312	1.00
437_T	453_W	2.298	1.00
225_Y	228_S	2.287	1.00
342_T	379_S	2.267	1.00
409_F	438_I	2.259	1.00
323_H	358_T	2.251	1.00
441_A	451_T	2.248	1.00
316_D	319_T	2.233	1.00
338_Q	377_V	2.197	1.00
431_V	436_G	2.190	1.00
328_V	362_L	2.150	1.00
400_I	408_I	2.138	1.00
313_Q	354_P	2.053	1.00
431_V	452_L	2.047	1.00
277_G	280_A	2.026	1.00
402_A	405_L	2.015	1.00
360_V	427_V	1.990	1.00
442_S	448_S	1.983	1.00
312_L	351_Q	1.963	1.00
400_I	404_Q	1.960	1.00
372_I	376_G	1.942	1.00
332_A	369_I	1.926	1.00
404_Q	407_A	1.921	1.00
407_A	410_T	1.909	1.00
376_G	396_S	1.902	1.00
407_A	413_F	1.886	1.00
352_A	357_L	1.878	1.00
439_Q	453_W	1.856	1.00
268_K	288_A	1.856	1.00
264_K	295_N	1.801	1.00
404_Q	413_F	1.801	1.00
360_V	430_I	1.800	1.00
276_A	280_A	1.796	1.00
385_S	390_K	1.791	1.00
314_A	349_E	1.780	1.00
295_N	299_S	1.760	1.00
230_Q	233_Q	1.758	1.00
267_A	288_A	1.756	1.00
366_L	370_Q	1.721	1.00
225_Y	229_R	1.717	1.00
404_Q	415_T	1.687	1.00
247_H	251_G	1.662	1.00
432_E	437_T	1.632	1.00
361_L	391_I	1.625	1.00
263_I	291_A	1.618	1.00
384_E	456_V	1.608	1.00
233_Q	236_M	1.601	1.00
288_A	292_D	1.598	1.00
353_D	356_R	1.590	1.00
266_L	283_L	1.575	1.00
233_Q	237_K	1.569	1.00
271_A	281_H	1.559	1.00
379_S	396_S	1.552	1.00
430_I	434_H	1.549	1.00
270_F	284_A	1.540	1.00
363_N	427_V	1.529	1.00
329_S	333_N	1.528	1.00
245_L	249_A	1.524	1.00
323_H	354_P	1.520	1.00
391_I	452_L	1.509	1.00
372_I	378_I	1.496	1.00
400_I	448_S	1.494	1.00
318_N	382_A	1.490	1.00
236_M	239_K	1.478	1.00
32_V	36_R	1.475	1.00
354_P	358_T	1.470	1.00
273_R	280_A	1.456	1.00
232_L	235_E	1.452	1.00
401_A	444_E	1.436	1.00
222_Y	225_Y	1.433	1.00
235_E	238_R	1.430	1.00
235_E	239_K	1.428	1.00
318_N	322_N	1.420	1.00
262_S	266_L	1.410	1.00
409_F	440_V	1.407	1.00
325_L	341_F	1.406	1.00
231_L	235_E	1.404	1.00
264_K	288_A	1.404	1.00
232_L	236_M	1.396	1.00
410_T	413_F	1.387	1.00
356_R	433_Q	1.387	1.00
219_F	222_Y	1.378	1.00
266_L	286_V	1.359	1.00
276_A	279_E	1.355	1.00
316_D	349_E	1.352	1.00
310_L	353_D	1.352	1.00
356_R	430_I	1.343	1.00
408_I	440_V	1.323	1.00
97_D	101_I	1.322	1.00
356_R	359_Q	1.304	1.00
233_Q	239_K	1.299	1.00
322_N	341_F	1.295	1.00
243_V	247_H	1.286	1.00
442_S	446_K	1.266	1.00
267_A	291_A	1.263	1.00
263_I	287_M	1.258	1.00
327_L	358_T	1.254	1.00
360_V	452_L	1.253	1.00
431_V	438_I	1.251	1.00
296_R	355_D	1.250	1.00
414_T	417_A	1.248	1.00
262_S	290_E	1.246	1.00
149_L	152_P	1.242	1.00
221_W	225_Y	1.239	1.00
312_L	434_H	1.236	1.00
343_A	382_A	1.236	1.00
371_A	414_T	1.235	1.00
331_D	334_S	1.233	1.00
218_S	221_W	1.231	1.00
251_G	411_P	1.221	1.00
442_S	445_G	1.220	1.00
429_N	432_E	1.220	1.00
436_G	454_L	1.208	1.00
321_I	382_A	1.187	1.00
270_F	280_A	1.187	1.00
255_E	359_Q	1.181	1.00
211_V	215_S	1.173	1.00
395_D	447_G	1.171	1.00
265_G	269_Y	1.161	1.00
267_A	271_A	1.156	1.00
277_G	281_H	1.156	1.00
388_G	437_T	1.151	1.00
232_L	239_K	1.140	1.00
337_I	372_I	1.123	1.00
286_V	290_E	1.116	1.00
400_I	440_V	1.114	1.00
208_L	211_V	1.113	1.00
281_H	285_Q	1.112	1.00
411_P	429_N	1.112	1.00
285_Q	289_K	1.106	1.00
324_S	358_T	1.106	1.00
318_N	343_A	1.104	1.00
320_L	324_S	1.096	1.00
267_A	284_A	1.087	1.00
315_V	320_L	1.086	1.00
357_L	434_H	1.079	1.00
226_L	229_R	1.077	1.00
395_D	448_S	1.072	1.00
187_A	190_L	1.064	1.00
36_R	39_G	1.063	1.00
328_V	365_Y	1.062	1.00
300_E	356_R	1.055	1.00
409_F	450_F	1.049	1.00
389_V	456_V	1.048	1.00
324_S	362_L	1.048	1.00
344_N	383_S	1.040	1.00
405_L	409_F	1.031	1.00
138_T	142_P	1.028	1.00
310_L	356_R	1.027	1.00
247_H	411_P	1.017	1.00
440_V	448_S	1.014	1.00
299_S	303_E	1.011	1.00
220_F	225_Y	1.008	1.00
373_G	376_G	0.995	1.00
385_S	388_G	0.984	1.00
325_L	329_S	0.979	1.00
290_E	293_R	0.978	1.00
429_N	433_Q	0.975	1.00
436_G	452_L	0.974	1.00
282_Q	286_V	0.971	1.00
143_A	147_Y	0.971	1.00
218_S	225_Y	0.971	1.00
311_A	353_D	0.967	1.00
53_G	57_I	0.965	1.00
331_D	366_L	0.960	1.00
320_L	352_A	0.956	1.00
262_S	265_G	0.953	1.00
221_W	228_S	0.953	1.00
257_R	299_S	0.951	1.00
240_E	243_V	0.950	1.00
363_N	366_L	0.950	1.00
212_L	215_S	0.949	1.00
394_T	443_Q	0.949	1.00
42_S	46_R	0.946	1.00
358_T	362_L	0.944	1.00
371_A	398_K	0.934	1.00
122_Q	126_P	0.931	1.00
364_L	450_F	0.931	1.00
264_K	268_K	0.926	1.00
324_S	328_V	0.924	1.00
327_L	362_L	0.924	1.00
257_R	295_N	0.923	1.00
291_A	295_N	0.920	1.00
183_I	186_D	0.920	1.00
365_Y	380_V	0.919	1.00
368_A	378_I	0.917	1.00
312_L	435_G	0.914	1.00
304_L	425_A	0.914	1.00
399_G	448_S	0.912	1.00
147_Y	150_F	0.912	1.00
148_R	152_P	0.910	1.00
64_S	68_M	0.908	1.00
210_T	214_A	0.906	1.00
300_E	359_Q	0.906	1.00
310_L	433_Q	0.905	1.00
409_F	428_H	0.902	1.00
278_G	281_H	0.901	1.00
258_N	262_S	0.900	1.00
248_L	252_V	0.898	1.00
400_I	405_L	0.897	1.00
317_L	391_I	0.896	1.00
256_I	294_L	0.894	1.00
355_D	358_T	0.892	1.00
361_L	365_Y	0.891	1.00
190_L	193_T	0.890	1.00
216_V	220_F	0.890	1.00
385_S	453_W	0.886	1.00
289_K	323_H	0.886	1.00
431_V	454_L	0.884	1.00
319_T	323_H	0.884	1.00
312_L	352_A	0.881	1.00
150_F	154_S	0.878	1.00
287_M	291_A	0.877	1.00
293_R	358_T	0.873	1.00
414_T	419_G	0.871	1.00
325_L	339_L	0.871	1.00
296_R	300_E	0.869	1.00
81_L	84_M	0.868	1.00
208_L	212_L	0.866	1.00
219_F	225_Y	0.864	1.00
336_E	375_H	0.861	1.00
286_V	289_K	0.860	1.00
92_W	105_H	0.857	1.00
427_V	431_V	0.853	1.00
63_G	67_G	0.851	1.00
201_T	205_L	0.850	1.00
78_Q	82_E	0.846	1.00
230_Q	234_D	0.844	1.00
219_F	223_R	0.843	1.00
218_S	222_Y	0.843	1.00
337_I	369_I	0.842	1.00
359_Q	430_I	0.842	1.00
194_Q	197_E	0.838	1.00
428_H	437_T	0.833	1.00
328_V	366_L	0.832	1.00
337_I	341_F	0.832	1.00
315_V	354_P	0.830	1.00
400_I	406_D	0.830	1.00
330_Q	333_N	0.829	1.00
408_I	425_A	0.827	1.00
282_Q	285_Q	0.827	1.00
114_A	118_P	0.826	1.00
402_A	442_S	0.825	1.00
246_G	308_T	0.823	1.00
33_T	37_D	0.823	1.00
364_L	452_L	0.823	1.00
130_S	134_L	0.821	1.00
370_Q	417_A	0.821	1.00
364_L	438_I	0.821	1.00
285_Q	288_A	0.821	1.00
118_P	122_Q	0.819	1.00
362_L	366_L	0.818	1.00
252_V	301_L	0.816	1.00
43_E	46_R	0.812	1.00
234_D	238_R	0.809	1.00
229_R	233_Q	0.808	1.00
215_S	219_F	0.807	1.00
361_L	393_V	0.803	1.00
344_N	347_L	0.801	1.00
332_A	378_I	0.800	1.00
223_R	226_L	0.797	1.00
275_P	280_A	0.796	1.00
318_N	345_D	0.795	1.00
356_R	434_H	0.794	1.00
408_I	450_F	0.793	1.00
48_A	52_K	0.793	1.00
398_K	417_A	0.792	1.00
422_L	426_V	0.791	1.00
179_Q	183_I	0.790	1.00
244_A	247_H	0.786	1.00
292_D	295_N	0.783	1.00
283_L	286_V	0.781	1.00
338_Q	341_F	0.781	1.00
215_S	218_S	0.778	1.00
254_H	363_N	0.778	1.00
324_S	365_Y	0.777	1.00
321_I	380_V	0.777	1.00
271_A	284_A	0.775	1.00
222_Y	226_L	0.772	1.00
50_L	54_N	0.769	1.00
260_L	298_V	0.768	1.00
330_Q	334_S	0.767	1.00
220_F	228_S	0.765	1.00
380_V	393_V	0.765	1.00
214_A	225_Y	0.764	1.00
395_D	398_K	0.760	1.00
364_L	427_V	0.760	1.00
42_S	45_D	0.755	1.00
41_A	44_A	0.754	1.00
387_A	456_V	0.752	1.00
370_Q	419_G	0.749	1.00
273_R	276_A	0.749	1.00
303_E	359_Q	0.748	1.00
269_Y	273_R	0.747	1.00
236_M	240_E	0.743	1.00
201_T	204_I	0.742	1.00
280_A	283_L	0.741	1.00
223_R	228_S	0.741	1.00
65_R	68_M	0.740	1.00
436_G	455_P	0.740	1.00
44_A	48_A	0.740	1.00
290_E	327_L	0.737	1.00
402_A	443_Q	0.736	1.00
365_Y	378_I	0.732	1.00
53_G	56_L	0.731	1.00
91_L	94_A	0.728	1.00
212_L	216_V	0.728	1.00
217_L	221_W	0.725	1.00
255_E	363_N	0.725	1.00
181_I	190_L	0.719	1.00
190_L	194_Q	0.718	1.00
333_N	336_E	0.718	1.00
321_I	361_L	0.714	1.00
303_E	356_R	0.713	1.00
215_S	225_Y	0.710	1.00
317_L	389_V	0.710	1.00
322_N	343_A	0.709	1.00
146_V	150_F	0.709	1.00
63_G	66_V	0.709	1.00
234_D	237_K	0.705	1.00
269_Y	283_L	0.701	1.00
132_W	224_R	0.701	1.00
143_A	146_V	0.700	1.00
400_I	442_S	0.699	1.00
214_A	217_L	0.698	1.00
57_I	61_E	0.698	1.00
322_N	326_Q	0.697	1.00
45_D	48_A	0.697	1.00
150_F	153_M	0.697	1.00
144_L	147_Y	0.696	1.00
335_R	374_Q	0.695	1.00
370_Q	416_K	0.695	1.00
39_G	42_S	0.694	1.00
364_L	431_V	0.693	1.00
54_N	58_R	0.693	1.00
77_Q	81_L	0.692	1.00
372_I	375_H	0.690	1.00
49_L	53_G	0.687	1.00
35_I	38_Y	0.687	1.00
326_Q	329_S	0.686	1.00
119_D	123_K	0.686	1.00
94_A	102_I	0.684	1.00
133_R	137_K	0.683	1.00
214_A	218_S	0.681	1.00
392_S	441_A	0.681	1.00
401_A	415_T	0.680	1.00
223_R	227_R	0.680	1.00
211_V	214_A	0.678	1.00
266_L	290_E	0.675	1.00
332_A	339_L	0.674	1.00
320_L	357_L	0.673	1.00
328_V	369_I	0.671	1.00
210_T	216_V	0.671	1.00
52_K	55_V	0.668	1.00
96_T	102_I	0.668	1.00
217_L	220_F	0.668	1.00
292_D	296_R	0.667	1.00
221_W	224_R	0.665	1.00
331_D	335_R	0.665	1.00
405_L	441_A	0.665	1.00
117_S	120_E	0.665	1.00
317_L	350_I	0.665	1.00
344_N	382_A	0.664	1.00
337_I	378_I	0.662	1.00
315_V	351_Q	0.659	1.00
97_D	103_I	0.658	1.00
121_M	125_K	0.658	1.00
28_G	32_V	0.657	1.00
283_L	287_M	0.654	1.00
148_R	151_Q	0.652	1.00
139_E	143_A	0.649	1.00
257_R	302_L	0.649	1.00
258_N	265_G	0.647	1.00
294_L	298_V	0.647	1.00
102_I	106_S	0.646	1.00
210_T	213_L	0.645	1.00
270_F	283_L	0.644	1.00
47_Q	50_L	0.644	1.00
183_I	197_E	0.644	1.00
370_Q	418_E	0.642	1.00
32_V	35_I	0.641	1.00
113_R	117_S	0.640	1.00
181_I	186_D	0.639	1.00
232_L	237_K	0.638	1.00
347_L	382_A	0.638	1.00
336_E	374_Q	0.636	1.00
181_I	184_A	0.635	1.00
249_A	253_A	0.634	1.00
206_F	209_A	0.633	1.00
220_F	223_R	0.632	1.00
414_T	418_E	0.631	1.00
203_I	207_A	0.631	1.00
439_Q	452_L	0.631	1.00
217_L	228_S	0.627	1.00
254_H	258_N	0.626	1.00
46_R	50_L	0.624	1.00
121_M	124_L	0.622	1.00
335_R	369_I	0.621	1.00
213_L	218_S	0.620	1.00
33_T	36_R	0.620	1.00
344_N	381_T	0.619	1.00
279_E	283_L	0.617	1.00
100_G	104_L	0.617	1.00
230_Q	236_M	0.616	1.00
368_A	393_V	0.616	1.00
203_I	208_L	0.616	1.00
186_D	197_E	0.615	1.00
319_T	322_N	0.615	1.00
145_E	148_R	0.614	1.00
268_K	272_E	0.612	1.00
237_K	240_E	0.612	1.00
56_L	60_L	0.612	1.00
146_V	151_Q	0.612	1.00
323_H	327_L	0.609	1.00
300_E	355_D	0.609	1.00
193_T	197_E	0.608	1.00
64_S	67_G	0.608	1.00
308_T	411_P	0.607	1.00
268_K	271_A	0.606	1.00
224_R	228_S	0.606	1.00
261_S	265_G	0.605	1.00
59_A	63_G	0.602	1.00
405_L	450_F	0.602	1.00
79_A	82_E	0.602	1.00
266_L	287_M	0.601	1.00
404_Q	416_K	0.601	1.00
80_L	84_M	0.601	1.00
209_A	213_L	0.600	1.00
262_S	286_V	0.599	1.00
243_V	246_G	0.597	1.00
325_L	380_V	0.596	1.00
402_A	406_D	0.596	1.00
360_V	434_H	0.595	1.00
213_L	217_L	0.594	1.00
114_A	117_S	0.594	1.00
344_N	348_P	0.594	1.00
130_S	133_R	0.594	1.00
75_V	78_Q	0.593	1.00
61_E	65_R	0.593	1.00
137_K	140_T	0.592	1.00
205_L	210_T	0.591	1.00
58_R	62_S	0.590	1.00
58_R	61_E	0.589	1.00
132_W	136_G	0.589	1.00
31_A	35_I	0.587	1.00
97_D	100_G	0.586	1.00
284_A	288_A	0.586	1.00
275_P	281_H	0.585	1.00
357_L	361_L	0.585	1.00
237_K	241_K	0.584	1.00
197_E	200_N	0.583	1.00
92_W	106_S	0.583	1.00
77_Q	80_L	0.579	1.00
22_V	26_L	0.578	1.00
115_L	118_P	0.578	1.00
48_A	51_E	0.577	1.00
401_A	405_L	0.577	1.00
35_I	39_G	0.577	1.00
19_L	22_V	0.576	1.00
400_I	450_F	0.575	1.00
332_A	335_R	0.574	1.00
146_V	149_L	0.573	1.00
255_E	258_N	0.573	1.00
320_L	354_P	0.573	1.00
184_A	187_A	0.572	1.00
310_L	434_H	0.571	1.00
59_A	62_S	0.571	1.00
135_L	221_W	0.570	1.00
102_I	105_H	0.570	1.00
111_V	114_A	0.570	1.00
231_L	234_D	0.569	1.00
211_V	218_S	0.569	1.00
425_A	429_N	0.568	1.00
45_D	49_L	0.567	1.00
51_E	54_N	0.567	1.00
390_K	439_Q	0.566	1.00
261_S	266_L	0.566	1.00
348_P	389_V	0.565	1.00
206_F	213_L	0.562	1.00
248_L	255_E	0.562	1.00
322_N	325_L	0.561	1.00
246_G	250_A	0.561	1.00
410_T	428_H	0.561	1.00
120_E	124_L	0.560	1.00
312_L	315_V	0.559	1.00
378_I	393_V	0.559	1.00
179_Q	182_F	0.559	1.00
60_L	64_S	0.558	1.00
219_F	226_L	0.557	1.00
319_T	354_P	0.556	1.00
241_K	244_A	0.552	1.00
313_Q	355_D	0.552	1.00
123_K	126_P	0.552	1.00
326_Q	330_Q	0.552	1.00
219_F	228_S	0.551	1.00
207_A	216_V	0.550	1.00
112_G	115_L	0.550	1.00
105_H	108_P	0.549	1.00
316_D	347_L	0.548	1.00
249_A	252_V	0.548	1.00
120_E	123_K	0.547	1.00
370_Q	414_T	0.542	1.00
342_T	383_S	0.542	1.00
356_R	360_V	0.542	1.00
247_H	429_N	0.541	1.00
253_A	259_P	0.541	1.00
222_Y	228_S	0.541	1.00
208_L	215_S	0.540	1.00
137_K	143_A	0.540	1.00
47_Q	51_E	0.540	1.00
110_K	113_R	0.540	1.00
332_A	337_I	0.538	1.00
147_Y	152_P	0.538	1.00
203_I	206_F	0.538	1.00
359_Q	362_L	0.537	1.00
304_L	308_T	0.535	1.00
337_I	376_G	0.535	1.00
256_I	259_P	0.534	1.00
438_I	450_F	0.533	1.00
218_S	223_R	0.533	1.00
184_A	188_S	0.533	1.00
61_E	64_S	0.533	1.00
288_A	291_A	0.533	1.00
321_I	341_F	0.532	1.00
258_N	261_S	0.531	1.00
350_I	454_L	0.529	1.00
23_I	26_L	0.527	1.00
149_L	153_M	0.527	1.00
211_V	219_F	0.526	1.00
209_A	212_L	0.525	1.00
209_A	217_L	0.524	1.00
384_E	388_G	0.524	1.00
388_G	456_V	0.523	1.00
273_R	279_E	0.521	1.00
302_L	306_K	0.521	1.00
209_A	216_V	0.521	1.00
381_T	449_T	0.520	1.00
141_T	144_L	0.520	1.00
253_A	257_R	0.519	1.00
194_Q	198_K	0.519	1.00
20_P	23_I	0.518	1.00
321_I	325_L	0.518	1.00
179_Q	186_D	0.517	1.00
388_G	455_P	0.516	1.00
196_G	200_N	0.515	1.00
255_E	259_P	0.515	1.00
270_F	287_M	0.515	1.00
431_V	437_T	0.514	1.00
295_N	298_V	0.513	1.00
34_V	38_Y	0.513	1.00
357_L	454_L	0.512	1.00
264_K	267_A	0.512	1.00
302_L	305_V	0.511	1.00
280_A	284_A	0.511	1.00
184_A	193_T	0.511	1.00
394_T	446_K	0.510	1.00
411_P	425_A	0.510	1.00
320_L	358_T	0.509	1.00
24_V	28_G	0.509	1.00
207_A	210_T	0.509	1.00
145_E	149_L	0.509	1.00
444_E	447_G	0.506	1.00
186_D	191_V	0.506	1.00
82_E	86_G	0.506	1.00
426_V	430_I	0.506	1.00
256_I	297_V	0.505	1.00
144_L	149_L	0.504	1.00
50_L	53_G	0.504	1.00
54_N	57_I	0.504	1.00
216_V	219_F	0.504	1.00
304_L	411_P	0.503	1.00
203_I	211_V	0.503	1.00
52_K	56_L	0.503	1.00
332_A	336_E	0.503	1.00
205_L	209_A	0.502	1.00
147_Y	154_S	0.502	1.00
205_L	212_L	0.501	1.00
318_N	346_T	0.501	1.00
282_Q	326_Q	0.501	1.00
123_K	127_E	0.500	1.00
404_Q	408_I	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4i5sA	2	0.8258	100	0.339	Contact Map
3a0rA	2	0.7118	100	0.34	Contact Map
4gczA	2	0.7677	100	0.354	Contact Map
4q20A	2	0.4882	100	0.433	Contact Map
3d36A	2	0.4731	100	0.438	Contact Map
3jz3A	2	0.3398	100	0.445	Contact Map
4mpcA	2	0.6581	100	0.455	Contact Map
2c2aA	2	0.4946	100	0.457	Contact Map
2q8gA	2	0.6516	100	0.458	Contact Map
4bixA	2	0.486	100	0.46	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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