GREMLIN Database
RIML - Ribosomal-protein-serine acetyltransferase
UniProt: P13857 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10853
Length: 179 (164)
Sequences: 20074 (15267)
Seq/√Len: 1192.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
132_I145_A2.7491.00
111_S147_R2.7111.00
14_H73_F2.6461.00
14_H20_H2.4491.00
34_W102_E2.3891.00
153_E173_A2.3011.00
94_A127_L2.1901.00
10_S112_Q2.1541.00
134_C142_N2.1301.00
84_F121_Y2.1181.00
7_V75_E2.1001.00
152_L155_C2.0691.00
134_C145_A2.0271.00
8_S116_A2.0071.00
152_L170_N1.9721.00
143_Q146_L1.9531.00
8_S112_Q1.9371.00
142_N146_L1.8661.00
119_H123_Q1.8451.00
22_K48_E1.7751.00
96_I114_L1.7451.00
71_M78_L1.7251.00
128_R158_Q1.7231.00
118_I130_F1.7171.00
118_I150_F1.7161.00
16_V71_M1.6831.00
30_K102_E1.6401.00
155_C170_N1.6331.00
23_P78_L1.5881.00
101_D104_H1.5711.00
114_L148_N1.5511.00
82_I113_A1.5401.00
21_V52_R1.5291.00
142_N152_L1.5231.00
48_E52_R1.5171.00
73_F76_D1.5111.00
116_A119_H1.5001.00
47_S50_D1.4981.00
136_V168_D1.4731.00
12_E75_E1.4341.00
54_T58_N1.4261.00
161_F166_Y1.4251.00
142_N170_N1.4051.00
146_L152_L1.3981.00
18_E56_Q1.3761.00
100_L110_I1.3691.00
74_K79_I1.3591.00
139_P142_N1.3381.00
6_K116_A1.3251.00
98_Y145_A1.3221.00
128_R166_Y1.3061.00
111_S144_V1.3051.00
7_V12_E1.2821.00
72_I113_A1.2741.00
82_I117_L1.2481.00
79_I104_H1.2331.00
72_I100_L1.2301.00
23_P77_E1.2231.00
12_E73_F1.2101.00
120_H124_S1.2071.00
74_K109_I1.2031.00
142_N172_Y1.2011.00
136_V155_C1.1981.00
21_V55_V1.1941.00
159_A169_V1.1861.00
121_Y130_F1.1761.00
77_E103_S1.1511.00
156_L171_L1.1301.00
137_D167_D1.1231.00
129_R173_A1.1231.00
25_Y48_E1.1091.00
121_Y125_G1.0841.00
110_I144_V1.0821.00
98_Y141_S1.0801.00
77_E104_H1.0771.00
52_R56_Q1.0641.00
34_W105_Q1.0581.00
129_R153_E1.0531.00
27_L101_D1.0491.00
157_K173_A1.0441.00
6_K13_L1.0411.00
81_V99_W1.0411.00
21_V48_E1.0391.00
8_S11_L1.0391.00
105_Q140_Q1.0351.00
18_E52_R1.0331.00
102_E105_Q1.0311.00
88_E91_N1.0261.00
95_E133_K1.0151.00
34_W37_Q1.0091.00
158_Q168_D1.0051.00
6_K120_H0.9941.00
23_P26_Q0.9901.00
93_T131_V0.9801.00
70_F120_H0.9791.00
70_F117_L0.9771.00
132_I150_F0.9771.00
141_S145_A0.9761.00
144_V148_N0.9661.00
60_M64_R0.9651.00
46_Q50_D0.9631.00
155_C168_D0.9621.00
27_L99_W0.9591.00
111_S115_Q0.9571.00
134_C172_Y0.9571.00
145_A150_F0.9431.00
120_H125_G0.9371.00
152_L172_Y0.9331.00
45_V51_T0.9261.00
25_Y29_C0.9231.00
30_K34_W0.9151.00
118_I148_N0.9101.00
53_K57_G0.9071.00
74_K107_Q0.9041.00
30_K101_D0.8981.00
157_K168_D0.8971.00
106_G140_Q0.8761.00
30_K103_S0.8751.00
135_R167_D0.8731.00
139_P143_Q0.8721.00
73_F78_L0.8671.00
84_F117_L0.8641.00
35_L105_Q0.8631.00
18_E59_V0.8581.00
98_Y110_I0.8581.00
121_Y127_L0.8571.00
74_K77_E0.8511.00
77_E101_D0.8501.00
26_Q101_D0.8491.00
115_Q119_H0.8471.00
93_T129_R0.8471.00
111_S148_N0.8461.00
12_E76_D0.8341.00
112_Q116_A0.8331.00
20_H73_F0.8251.00
16_V81_V0.8221.00
92_K166_Y0.8131.00
11_L109_I0.8081.00
153_E157_K0.8021.00
136_V170_N0.7991.00
38_S135_R0.7981.00
100_L109_I0.7921.00
49_E52_R0.7921.00
22_K26_Q0.7891.00
18_E21_V0.7891.00
11_L113_A0.7861.00
115_Q148_N0.7861.00
26_Q77_E0.7851.00
21_V25_Y0.7751.00
93_T159_A0.7681.00
28_I99_W0.7681.00
74_K104_H0.7611.00
139_P146_L0.7521.00
156_L159_A0.7511.00
146_L172_Y0.7471.00
25_Y51_T0.7411.00
104_H107_Q0.7361.00
14_H71_M0.7351.00
92_K161_F0.7271.00
50_D53_K0.7271.00
15_A62_H0.7171.00
26_Q30_K0.7141.00
158_Q166_Y0.7091.00
95_E131_V0.7081.00
134_C141_S0.7041.00
56_Q60_M0.7041.00
53_K56_Q0.6991.00
114_L144_V0.6991.00
161_F165_A0.6971.00
49_E53_K0.6961.00
23_P101_D0.6951.00
132_I141_S0.6931.00
38_S137_D0.6851.00
106_G111_S0.6831.00
26_Q103_S0.6801.00
8_S13_L0.6781.00
98_Y114_L0.6751.00
133_K156_L0.6741.00
9_E112_Q0.6661.00
110_I114_L0.6661.00
10_S108_G0.6641.00
143_Q147_R0.6611.00
109_I112_Q0.6521.00
69_M83_S0.6511.00
27_L78_L0.6481.00
111_S140_Q0.6451.00
134_C170_N0.6421.00
72_I109_I0.6371.00
106_G143_Q0.6331.00
79_I109_I0.6321.00
94_A121_Y0.6311.00
36_Q39_L0.6301.00
72_I82_I0.6301.00
140_Q143_Q0.6251.00
133_K169_V0.6191.00
137_D165_A0.6181.00
58_N69_M0.6151.00
72_I80_G0.6141.00
84_F94_A0.6101.00
51_T55_V0.6051.00
98_Y144_V0.5991.00
151_I157_K0.5971.00
100_L104_H0.5901.00
46_Q51_T0.5881.00
92_K128_R0.5821.00
154_G173_A0.5801.00
136_V142_N0.5791.00
82_I114_L0.5741.00
100_L105_Q0.5741.00
106_G144_V0.5731.00
162_L167_D0.5711.00
10_S75_E0.5691.00
35_L99_W0.5661.00
78_L81_V0.5611.00
23_P73_F0.5601.00
57_G60_M0.5571.00
11_L112_Q0.5561.00
162_L165_A0.5551.00
17_A20_H0.5521.00
30_K105_Q0.5441.00
39_L99_W0.5441.00
161_F164_D0.5431.00
14_H17_A0.5421.00
62_H68_K0.5381.00
118_I122_A0.5381.00
129_R159_A0.5371.00
36_Q43_Q0.5361.00
114_L150_F0.5361.00
160_E169_V0.5301.00
131_V156_L0.5301.00
15_A59_V0.5301.00
22_K25_Y0.5291.00
132_I172_Y0.5271.00
145_A172_Y0.5261.00
67_A83_S0.5241.00
133_K171_L0.5201.00
55_V59_V0.5181.00
131_V159_A0.5161.00
94_A130_F0.5151.00
36_Q41_W0.5141.00
16_V24_L0.5091.00
154_G157_K0.5091.00
83_S97_G0.5031.00
15_A63_Q0.5021.00
72_I110_I0.5021.00
59_V62_H0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3r9fA 1 0.9832 100 0.272 Contact Map
1s7kA 2 0.8827 100 0.294 Contact Map
2fckA 2 0.9553 100 0.299 Contact Map
2vzyA 3 0.8883 100 0.304 Contact Map
3pzjA 2 0.9665 100 0.306 Contact Map
1nslA 3 0.9944 100 0.307 Contact Map
1yreA 2 0.9385 100 0.308 Contact Map
2z10A 2 0.9665 100 0.309 Contact Map
3fbuA 2 0.9218 100 0.335 Contact Map
3igrA 2 0.9888 100 0.347 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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