MNGR - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

MNGR - Mannosyl-D-glycerate transport/metabolism system repressor MngR

UniProt:	P13669	Sequences: MGHKPLYRQIADRIREQIARGELKPGDALPTESALQTEFGVSRVTVRQALRQLVEQQILESIQGSGTYVKEERVNYDIFQLTSFDEKLSDRHVDTHSEVLIFEVIPADDFLQQQLQITPQDRVWHVKRVRYRKQKPMALEETWMPLALFPDLTWQVMENSKYHFIEEVKKMVIDRSEQEIIPLMPTEEMSRLLNISQTKPILEKVSRGYLVDGRVFEYSRNAFNTDDYKFTLIAQRKSSR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11109
Length:	240 (195)
Sequences:	19896 (15359)
Seq/√Len:	1099.8

ECOLI - MNGR YIHL YIDP PHNF FRLR YEGW
BACSU - GMUR YBGA TRER YYDK YURK YVOA YMFC

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
24_K	27_D	4.055	1.00
17_Q	22_E	3.805	1.00
15_R	56_Q	3.311	1.00
11_A	52_Q	3.020	1.00
17_Q	38_E	3.012	1.00
60_E	70_K	2.959	1.00
121_D	181_I	2.648	1.00
62_I	65_S	2.625	1.00
10_I	41_V	2.518	1.00
128_R	174_D	2.416	1.00
13_R	17_Q	2.385	1.00
32_E	43_R	2.312	1.00
28_A	68_Y	2.272	1.00
61_S	67_T	2.225	1.00
184_M	187_E	2.165	1.00
10_I	39_F	2.155	1.00
65_S	68_Y	2.106	1.00
16_E	20_R	2.095	1.00
106_P	189_M	2.074	1.00
13_R	39_F	2.071	1.00
11_A	56_Q	2.067	1.00
11_A	15_R	1.862	1.00
54_V	61_S	1.858	1.00
15_R	19_A	1.796	1.00
48_Q	51_R	1.781	1.00
187_E	191_R	1.757	1.00
15_R	58_I	1.756	1.00
125_H	141_E	1.693	1.00
50_L	59_L	1.677	1.00
116_Q	153_T	1.654	1.00
186_T	189_M	1.632	1.00
34_A	38_E	1.616	1.00
112_Q	117_I	1.615	1.00
111_L	143_W	1.613	1.00
59_L	67_T	1.566	1.00
127_K	141_E	1.564	1.00
6_L	9_Q	1.562	1.00
17_Q	23_L	1.558	1.00
54_V	59_L	1.522	1.00
13_R	16_E	1.521	1.00
108_D	111_L	1.502	1.00
9_Q	13_R	1.498	1.00
96_H	131_Y	1.492	1.00
25_P	71_E	1.442	1.00
33_S	37_T	1.435	1.00
35_L	46_V	1.425	1.00
32_E	47_R	1.424	1.00
133_K	136_P	1.406	1.00
34_A	37_T	1.387	1.00
41_V	46_V	1.386	1.00
31_T	34_A	1.378	1.00
51_R	61_S	1.368	1.00
51_R	55_E	1.342	1.00
17_Q	21_G	1.333	1.00
110_F	185_P	1.316	1.00
123_V	140_E	1.313	1.00
189_M	193_L	1.299	1.00
18_I	69_V	1.276	1.00
117_I	181_I	1.276	1.00
60_E	68_Y	1.274	1.00
113_Q	116_Q	1.268	1.00
163_H	167_E	1.259	1.00
98_E	131_Y	1.247	1.00
7_Y	52_Q	1.243	1.00
128_R	170_K	1.230	1.00
118_T	121_D	1.227	1.00
5_P	8_R	1.219	1.00
179_E	187_E	1.214	1.00
99_V	103_E	1.202	1.00
139_L	189_M	1.193	1.00
23_L	69_V	1.183	1.00
112_Q	183_L	1.178	1.00
147_A	150_P	1.176	1.00
127_K	188_E	1.166	1.00
19_A	58_I	1.166	1.00
196_S	199_K	1.163	1.00
105_I	125_H	1.157	1.00
28_A	66_G	1.151	1.00
104_V	122_R	1.131	1.00
126_V	143_W	1.127	1.00
185_P	195_I	1.119	1.00
51_R	54_V	1.099	1.00
52_Q	56_Q	1.095	1.00
104_V	146_L	1.092	1.00
62_I	68_Y	1.089	1.00
123_V	143_W	1.083	1.00
62_I	66_G	1.082	1.00
52_Q	55_E	1.082	1.00
150_P	158_E	1.070	1.00
92_H	95_T	1.061	1.00
177_E	181_I	1.048	1.00
48_Q	52_Q	1.046	1.00
119_P	147_A	1.042	1.00
130_R	140_E	1.039	1.00
146_L	150_P	1.035	1.00
107_A	111_L	1.033	1.00
92_H	155_Q	1.026	1.00
178_Q	182_P	1.020	1.00
17_Q	39_F	1.019	1.00
98_E	102_F	1.011	1.00
121_D	177_E	1.010	1.00
6_L	45_T	1.001	1.00
12_D	15_R	0.993	1.00
86_E	90_D	0.985	1.00
182_P	187_E	0.984	1.00
14_I	35_L	0.981	1.00
92_H	96_H	0.981	1.00
23_L	27_D	0.980	1.00
117_I	121_D	0.972	1.00
122_R	126_V	0.952	1.00
8_R	12_D	0.946	1.00
26_G	60_E	0.943	1.00
50_L	67_T	0.936	1.00
8_R	52_Q	0.924	1.00
126_V	140_E	0.921	1.00
174_D	178_Q	0.921	1.00
101_I	125_H	0.920	1.00
95_T	111_L	0.917	1.00
145_P	148_L	0.912	1.00
195_I	199_K	0.902	1.00
10_I	46_V	0.899	1.00
106_P	185_P	0.887	1.00
106_P	186_T	0.883	1.00
184_M	199_K	0.875	1.00
165_I	168_V	0.875	1.00
190_S	194_N	0.867	1.00
117_I	177_E	0.866	1.00
101_I	127_K	0.852	1.00
121_D	125_H	0.851	1.00
112_Q	116_Q	0.846	1.00
64_G	67_T	0.846	1.00
120_Q	147_A	0.843	1.00
50_L	54_V	0.831	1.00
117_I	183_L	0.831	1.00
152_L	158_E	0.829	1.00
7_Y	11_A	0.827	1.00
187_E	190_S	0.826	1.00
106_P	122_R	0.825	1.00
93_V	96_H	0.814	1.00
119_P	150_P	0.806	1.00
13_R	38_E	0.806	1.00
144_M	177_E	0.805	1.00
126_V	130_R	0.804	1.00
105_I	111_L	0.803	1.00
143_W	147_A	0.803	1.00
119_P	123_V	0.798	1.00
164_F	168_V	0.798	1.00
10_I	13_R	0.793	1.00
136_P	139_L	0.789	1.00
98_E	193_L	0.787	1.00
124_W	177_E	0.785	1.00
87_K	91_R	0.780	1.00
36_Q	46_V	0.776	1.00
14_I	23_L	0.774	1.00
12_D	16_E	0.770	1.00
127_K	139_L	0.768	1.00
103_E	106_P	0.768	1.00
105_I	109_D	0.764	1.00
112_Q	120_Q	0.762	1.00
121_D	147_A	0.759	1.00
147_A	151_D	0.759	1.00
192_L	195_I	0.752	1.00
7_Y	48_Q	0.751	1.00
29_L	59_L	0.751	1.00
124_W	174_D	0.750	1.00
107_A	123_V	0.747	1.00
125_H	143_W	0.745	1.00
30_P	38_E	0.738	1.00
162_Y	166_E	0.737	1.00
160_S	164_F	0.735	1.00
25_P	70_K	0.733	1.00
141_E	145_P	0.732	1.00
26_G	71_E	0.731	1.00
185_P	189_M	0.731	1.00
84_F	88_L	0.727	1.00
88_L	132_R	0.727	1.00
42_S	45_T	0.726	1.00
17_Q	20_R	0.725	1.00
125_H	128_R	0.725	1.00
86_E	89_S	0.722	1.00
102_F	193_L	0.722	1.00
183_L	189_M	0.721	1.00
126_V	129_V	0.721	1.00
188_E	192_L	0.716	1.00
50_L	61_S	0.712	1.00
139_L	143_W	0.711	1.00
100_L	129_V	0.709	1.00
123_V	147_A	0.709	1.00
119_P	122_R	0.704	1.00
32_E	61_S	0.702	1.00
97_S	130_R	0.701	1.00
186_T	190_S	0.697	1.00
99_V	157_M	0.696	1.00
170_K	174_D	0.695	1.00
112_Q	151_D	0.692	1.00
121_D	174_D	0.687	1.00
129_V	136_P	0.686	1.00
111_L	115_L	0.686	1.00
156_V	159_N	0.686	1.00
109_D	119_P	0.683	1.00
163_H	166_E	0.681	1.00
171_M	175_R	0.680	1.00
28_A	31_T	0.675	1.00
28_A	65_S	0.669	1.00
162_Y	165_I	0.668	1.00
39_F	46_V	0.665	1.00
37_T	40_G	0.660	1.00
89_S	92_H	0.655	1.00
16_E	19_A	0.655	1.00
103_E	107_A	0.652	1.00
89_S	95_T	0.642	1.00
102_F	189_M	0.640	1.00
164_F	169_K	0.635	1.00
120_Q	123_V	0.635	1.00
35_L	39_F	0.634	1.00
85_D	89_S	0.632	1.00
36_Q	39_F	0.625	1.00
97_S	101_I	0.622	1.00
93_V	133_K	0.618	1.00
145_P	173_I	0.618	1.00
125_H	129_V	0.618	1.00
77_D	80_Q	0.615	1.00
103_E	189_M	0.611	1.00
115_L	120_Q	0.609	1.00
176_S	191_R	0.606	1.00
122_R	146_L	0.605	1.00
96_H	134_Q	0.605	1.00
102_F	106_P	0.602	1.00
23_L	29_L	0.602	1.00
114_Q	183_L	0.600	1.00
33_S	36_Q	0.599	1.00
153_T	156_V	0.598	1.00
105_I	108_D	0.597	1.00
35_L	50_L	0.596	1.00
160_S	165_I	0.592	1.00
126_V	136_P	0.591	1.00
89_S	94_D	0.591	1.00
104_V	149_F	0.586	1.00
104_V	124_W	0.585	1.00
44_V	48_Q	0.580	1.00
103_E	125_H	0.580	1.00
36_Q	43_R	0.578	1.00
136_P	140_E	0.576	1.00
139_L	192_L	0.576	1.00
192_L	196_S	0.576	1.00
45_T	48_Q	0.572	1.00
102_F	105_I	0.571	1.00
101_I	105_I	0.567	1.00
105_I	143_W	0.564	1.00
107_A	112_Q	0.562	1.00
102_F	153_T	0.561	1.00
109_D	112_Q	0.554	1.00
22_E	38_E	0.553	1.00
23_L	30_P	0.553	1.00
123_V	126_V	0.552	1.00
164_F	167_E	0.551	1.00
54_V	67_T	0.551	1.00
31_T	46_V	0.550	1.00
124_W	128_R	0.549	1.00
107_A	117_I	0.548	1.00
178_Q	181_I	0.548	1.00
175_R	187_E	0.547	1.00
46_V	49_A	0.547	1.00
76_Y	80_Q	0.547	1.00
149_F	165_I	0.546	1.00
85_D	88_L	0.544	1.00
108_D	143_W	0.543	1.00
148_L	180_I	0.541	1.00
144_M	161_K	0.534	1.00
112_Q	119_P	0.530	1.00
46_V	59_L	0.529	1.00
141_E	189_M	0.526	1.00
190_S	197_Q	0.525	1.00
8_R	11_A	0.523	1.00
33_S	43_R	0.521	1.00
166_E	172_V	0.518	1.00
118_T	122_R	0.516	1.00
98_E	197_Q	0.516	1.00
57_Q	70_K	0.515	1.00
11_A	49_A	0.513	1.00
115_L	119_P	0.511	1.00
99_V	102_F	0.511	1.00
98_E	129_V	0.509	1.00
116_Q	151_D	0.509	1.00
109_D	113_Q	0.509	1.00
115_L	123_V	0.508	1.00
36_Q	44_V	0.507	1.00
83_S	87_K	0.505	1.00
160_S	163_H	0.503	1.00
120_Q	151_D	0.502	1.00
10_I	14_I	0.502	1.00
116_Q	119_P	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4u0wA	2	0.9875	100	0.132	Contact Map
3f8mA	2	0.9542	100	0.157	Contact Map
3edpA	2	0.9125	100	0.165	Contact Map
2ra5A	2	0.6167	100	0.167	Contact Map
3eetA	2	0.9583	100	0.169	Contact Map
3bwgA	2	0.95	100	0.192	Contact Map
3f8lA	2	0.6792	100	0.434	Contact Map
1hw1A	2	0.8083	99.9	0.506	Contact Map
4p96A	2	0.8917	99.9	0.526	Contact Map
2di3A	2	0.8292	99.9	0.527	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0084 seconds.