GREMLIN Database
SBCC - Nuclease SbcCD subunit C
UniProt: P13458 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10927
Length: 1048 (955)
Sequences: 2850 (2624)
Seq/√Len: 84.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
82_E95_F3.2941.00
894_K898_F3.2811.00
917_R1003_A3.2361.00
480_V484_C3.1951.00
342_Q345_Q3.1661.00
261_R265_A3.1481.00
335_A338_S3.0541.00
217_Q228_L2.9601.00
272_E275_K2.9591.00
594_P597_D2.7871.00
725_Q728_A2.7521.00
824_T827_Q2.6771.00
217_Q221_L2.6511.00
649_T652_G2.6451.00
135_L138_T2.6271.00
303_S310_R2.6171.00
217_Q220_S2.6031.00
82_E93_R2.5851.00
344_Q347_S2.5711.00
296_W303_S2.5241.00
224_S228_L2.5231.00
438_Q442_L2.4691.00
933_E938_D2.4681.00
474_T478_A2.4401.00
459_R462_A2.4331.00
463_L466_M2.4261.00
575_Q578_T2.4151.00
569_S573_D2.3971.00
225_L228_L2.3701.00
776_E780_T2.3601.00
541_K545_E2.3531.00
531_R535_L2.3341.00
235_L239_Q2.3331.00
932_L938_D2.3081.00
534_A538_E2.3061.00
236_I239_Q2.2981.00
298_R301_E2.2881.00
322_S326_L2.2871.00
653_Y657_L2.2621.00
277_Q284_S2.2431.00
218_V228_L2.2391.00
716_L720_R2.2371.00
501_Q504_Q2.2371.00
709_H713_T2.2291.00
473_K476_Q2.2191.00
270_L277_Q2.2161.00
751_Q755_D2.1771.00
303_S306_L2.1551.00
197_R201_E2.1511.00
601_W604_A2.1491.00
713_T717_E2.1491.00
5_S19_K2.1431.00
702_P706_E2.1211.00
7_R17_E2.1191.00
721_Q725_Q2.0951.00
259_A263_Q2.0941.00
663_E666_W2.0721.00
636_Q640_E2.0661.00
786_K789_L2.0611.00
562_R566_E2.0561.00
781_Q785_L2.0561.00
231_E235_L2.0541.00
3_I83_V2.0431.00
580_Q583_A2.0391.00
931_A938_D2.0381.00
267_Q270_L2.0361.00
234_Q238_A2.0321.00
730_H734_Q2.0311.00
7_R82_E2.0151.00
648_T652_G1.9991.00
364_E368_W1.9981.00
831_E834_Q1.9861.00
366_A369_R1.9861.00
360_Q364_E1.9851.00
397_N401_A1.9821.00
269_A273_E1.9771.00
444_Q448_A1.9741.00
328_A331_R1.9711.00
803_T810_H1.9661.00
895_F898_F1.9561.00
460_N464_N1.9561.00
309_I313_I1.9541.00
48_D162_L1.9521.00
254_E258_E1.9501.00
4_L91_A1.9351.00
932_L936_V1.9321.00
931_A936_V1.9211.00
296_W300_A1.9191.00
493_L497_R1.9171.00
492_T495_A1.9111.00
871_A875_Q1.9091.00
272_E276_A1.9091.00
604_A608_H1.9011.00
737_Q744_A1.8941.00
799_L802_Q1.8921.00
359_R362_N1.8841.00
385_W388_Q1.8831.00
281_A284_S1.8761.00
300_A303_S1.8711.00
647_L650_L1.8651.00
388_Q392_A1.8581.00
157_Q160_A1.8551.00
552_Q556_I1.8521.00
326_L330_I1.8491.00
529_Q533_L1.8441.00
279_Q282_A1.8391.00
837_Q841_E1.8311.00
736_L739_Q1.8271.00
650_L654_A1.8071.00
441_R444_Q1.8011.00
500_L503_G1.8001.00
481_K485_E1.7941.00
443_A446_Q1.7931.00
662_E666_W1.7911.00
86_E89_G1.7851.00
704_S708_P1.7781.00
741_V745_Q1.7751.00
477_L481_K1.7681.00
293_R296_W1.7591.00
351_W354_E1.7561.00
497_R500_L1.7501.00
489_R492_T1.7381.00
385_W389_L1.7351.00
659_Q662_E1.7351.00
421_Q425_R1.7321.00
455_E458_Q1.7311.00
46_L1030_V1.7281.00
542_L546_G1.7271.00
461_A465_E1.7211.00
337_Q340_E1.7211.00
251_R254_E1.7191.00
390_T393_E1.7141.00
220_S228_L1.7111.00
325_A329_S1.7081.00
778_T781_Q1.7071.00
783_E787_Q1.7051.00
311_Q315_E1.7021.00
221_L228_L1.7001.00
489_R493_L1.6891.00
718_N721_Q1.6811.00
642_R645_L1.6771.00
369_R372_F1.6761.00
739_Q742_L1.6691.00
395_K398_A1.6681.00
751_Q754_F1.6681.00
217_Q225_L1.6641.00
493_L496_Q1.6621.00
855_Q858_D1.6561.00
7_R19_K1.6511.00
1013_V1020_M1.6511.00
270_L273_E1.6481.00
629_N633_I1.6481.00
705_D709_H1.6391.00
639_I643_Q1.6321.00
221_L225_L1.6301.00
623_G627_A1.6281.00
671_Q675_Q1.6201.00
228_L232_E1.6191.00
221_L224_S1.6191.00
307_A310_R1.6131.00
263_Q267_Q1.6121.00
401_A404_L1.6121.00
6_L22_F1.6111.00
627_A631_Q1.6081.00
332_H336_K1.6071.00
499_Q503_G1.6031.00
556_I559_Q1.6031.00
643_Q647_L1.6011.00
22_F1012_G1.6001.00
392_A396_L1.5951.00
496_Q500_L1.5931.00
893_D897_K1.5911.00
655_L659_Q1.5901.00
933_E940_W1.5861.00
402_I406_L1.5791.00
905_D926_R1.5741.00
588_L591_T1.5731.00
590_I594_P1.5661.00
536_E540_K1.5641.00
932_L940_W1.5591.00
9_K17_E1.5491.00
864_Q868_Q1.5491.00
706_E709_H1.5491.00
329_S333_H1.5471.00
530_S534_A1.5461.00
599_Q603_D1.5431.00
315_E319_R1.5421.00
740_D744_A1.5371.00
265_A268_Q1.5361.00
225_L229_T1.5321.00
538_E541_K1.5301.00
384_Q388_Q1.5251.00
80_L97_S1.5231.00
938_D941_Q1.5211.00
312_Q316_V1.5181.00
931_A939_T1.5181.00
744_A748_Q1.5141.00
600_P604_A1.5131.00
327_R331_R1.5111.00
796_A799_L1.5101.00
806_T810_H1.5090.99
232_E236_I1.5070.99
986_F1017_V1.5060.99
932_L939_T1.5050.99
901_G905_D1.5000.99
218_V222_T1.4980.99
389_L393_E1.4960.99
318_T322_S1.4940.99
476_Q479_D1.4860.99
443_A447_V1.4840.99
439_Q443_A1.4830.99
420_E423_P1.4740.99
936_V939_T1.4650.99
252_Q256_Q1.4650.99
318_T321_Q1.4640.99
404_L407_T1.4620.99
690_R693_Q1.4600.99
473_K477_L1.4580.99
857_A861_Q1.4570.99
686_A690_R1.4560.99
892_G896_R1.4520.99
242_E246_L1.4510.99
356_D359_R1.4500.99
232_E238_A1.4500.99
626_A629_N1.4440.99
217_Q227_V1.4400.99
960_S967_L1.4370.99
958_L993_T1.4360.99
667_L670_R1.4350.99
717_E721_Q1.4340.99
931_A940_W1.4330.99
549_L553_L1.4310.99
274_E277_Q1.4260.99
361_W364_E1.4240.99
440_K444_Q1.4230.99
730_H733_Q1.4230.99
496_Q504_Q1.4200.99
466_M470_Y1.4170.99
475_Q478_A1.4150.99
362_N366_A1.4130.99
500_L504_Q1.4090.99
469_R472_E1.4040.99
834_Q838_K1.4030.99
704_S707_L1.4010.99
263_Q270_L1.4010.99
11_L63_N1.4010.99
466_M469_R1.3900.99
392_A395_K1.3850.99
685_T689_N1.3850.99
493_L500_L1.3830.99
748_Q755_D1.3820.99
699_E703_Q1.3820.99
870_I874_T1.3820.99
81_A96_W1.3800.99
561_Q564_E1.3790.99
347_S350_T1.3720.99
807_L812_Q1.3710.99
488_A492_T1.3700.99
428_L432_H1.3690.99
707_L711_E1.3690.99
640_E643_Q1.3690.99
389_L392_A1.3670.99
734_Q737_Q1.3660.99
496_Q503_G1.3660.99
199_E202_K1.3630.99
694_L698_L1.3610.99
620_E624_Q1.3590.99
217_Q224_S1.3590.99
276_A279_Q1.3550.99
362_N365_P1.3510.99
333_H336_K1.3490.99
31_G169_R1.3480.99
301_E305_A1.3450.99
706_E710_C1.3380.99
266_L270_L1.3380.99
314_E317_N1.3360.99
305_A308_H1.3350.99
94_A132_K1.3330.99
800_V810_H1.3260.99
495_A499_Q1.3260.99
246_L250_T1.3230.99
427_H430_A1.3210.99
787_Q790_E1.3190.99
328_A332_H1.3180.99
147_F154_S1.3170.99
1002_D1023_R1.3170.99
162_L173_L1.3140.99
573_D576_A1.3110.99
268_Q272_E1.3110.99
736_L740_D1.3100.99
255_L259_A1.3100.99
349_N352_L1.3090.99
399_L403_T1.3090.99
396_L399_L1.3070.99
417_Q421_Q1.3040.99
165_K168_E1.3030.99
303_S307_A1.3030.99
219_Q222_T1.3010.98
788_N792_Q1.2990.98
533_L537_N1.2970.98
398_A402_I1.2960.98
478_A481_K1.2950.98
275_K279_Q1.2940.98
236_I240_Q1.2940.98
977_I986_F1.2920.98
540_K543_G1.2880.98
695_T699_E1.2860.98
314_E318_T1.2860.98
343_Q347_S1.2850.98
447_V451_N1.2810.98
200_L207_A1.2810.98
429_V432_H1.2800.98
269_A272_E1.2780.98
603_D606_D1.2780.98
542_L545_E1.2770.98
394_Q397_N1.2760.98
787_Q791_N1.2760.98
583_A587_S1.2720.98
232_E239_Q1.2720.98
441_R445_L1.2710.98
664_E668_A1.2690.98
200_L209_G1.2650.98
563_D566_E1.2640.98
585_T589_N1.2630.98
807_L810_H1.2630.98
921_R939_T1.2610.98
80_L95_F1.2610.98
948_T956_S1.2580.98
811_Q814_R1.2570.98
479_D483_I1.2550.98
67_S70_D1.2550.98
471_K474_T1.2540.98
276_A280_L1.2540.98
147_F158_F1.2530.98
333_H337_Q1.2500.98
634_Q638_Q1.2470.98
319_R323_T1.2460.98
12_N45_T1.2460.98
324_M328_A1.2440.98
732_Q735_T1.2440.98
545_E549_L1.2430.98
239_Q832_L1.2420.98
395_K399_L1.2420.98
346_Q350_T1.2400.98
470_Y473_K1.2390.98
661_D664_E1.2350.98
860_R864_Q1.2350.98
312_Q315_E1.2340.98
753_Q756_T1.2340.98
957_F986_F1.2340.98
296_W310_R1.2330.98
700_T704_S1.2330.98
568_Q571_R1.2320.98
405_T408_A1.2320.98
427_H431_L1.2310.98
810_H814_R1.2260.98
4_L86_E1.2260.98
666_W670_R1.2260.98
597_D601_W1.2210.98
311_Q318_T1.2200.98
257_Q260_S1.2190.98
933_E941_Q1.2180.98
688_Q692_Q1.2180.98
964_A986_F1.2170.98
693_Q696_P1.2170.98
835_T839_L1.2170.98
492_T497_R1.2160.98
467_R471_K1.2150.98
750_A753_Q1.2150.98
383_R386_Q1.2140.98
492_T496_Q1.2100.98
739_Q743_A1.2080.98
393_E401_A1.2060.98
422_R426_Q1.2030.97
644_Q648_T1.2020.97
699_E702_P1.2010.97
663_E667_L1.2010.97
802_Q806_T1.2000.97
957_F987_G1.2000.97
315_E318_T1.1990.97
353_Q356_D1.1980.97
803_T806_T1.1970.97
786_K790_E1.1930.97
866_L869_Q1.1930.97
238_A831_E1.1910.97
458_Q462_A1.1900.97
365_P369_R1.1880.97
307_A311_Q1.1880.97
553_L557_T1.1870.97
624_Q627_A1.1870.97
844_T848_E1.1840.97
557_T561_Q1.1810.97
456_Q459_R1.1780.97
497_R503_G1.1750.97
369_R373_S1.1750.97
293_R297_E1.1750.97
451_N455_E1.1740.97
203_L206_Q1.1740.97
988_T1017_V1.1730.97
492_T500_L1.1720.97
606_D610_R1.1720.97
961_L1015_S1.1700.97
84_E93_R1.1690.97
668_A671_Q1.1670.97
496_Q502_A1.1660.97
626_A630_Q1.1650.97
737_Q741_V1.1620.97
476_Q480_V1.1590.97
645_L649_T1.1580.97
52_L70_D1.1580.97
742_L746_S1.1570.97
557_T564_E1.1570.97
637_Q641_Q1.1570.97
469_R476_Q1.1560.97
430_A434_Q1.1540.97
202_K205_A1.1540.97
622_Q626_A1.1520.97
157_Q968_S1.1500.97
334_A338_S1.1500.97
635_Y639_I1.1500.97
326_L329_S1.1480.97
619_H622_Q1.1480.97
434_Q438_Q1.1470.97
976_R980_L1.1450.97
933_E939_T1.1410.97
953_G984_E1.1390.96
570_L574_E1.1380.96
442_L446_Q1.1370.96
652_G655_L1.1360.96
386_Q390_T1.1350.96
985_G1017_V1.1330.96
347_S351_W1.1330.96
470_Y477_L1.1310.96
273_E277_Q1.1310.96
207_A210_V1.1250.96
154_S157_Q1.1220.96
998_L1017_V1.1170.96
271_A275_K1.1160.96
450_Q454_Q1.1160.96
354_E357_R1.1160.96
660_E664_E1.1160.96
697_I701_L1.1160.96
544_E548_T1.1150.96
462_A466_M1.1130.96
550_R554_D1.1120.96
372_F375_Q1.1110.96
693_Q697_I1.1090.96
795_Q799_L1.1090.96
933_E936_V1.1090.96
336_K340_E1.1080.96
465_E469_R1.1070.96
259_A262_R1.1030.96
493_L502_A1.1020.96
190_F194_K1.1000.96
779_L783_E1.1000.96
869_Q872_Q1.0990.96
79_C98_Q1.0960.96
387_Q391_H1.0960.96
535_L539_V1.0950.96
310_R318_T1.0910.96
337_Q341_L1.0900.95
805_E808_A1.0900.95
101_A113_R1.0900.95
159_A162_L1.0900.95
237_T241_Q1.0890.95
235_L238_A1.0880.95
299_I303_S1.0880.95
683_E686_A1.0850.95
654_A657_L1.0840.95
341_L345_Q1.0830.95
856_D860_R1.0800.95
647_L651_T1.0770.95
220_S224_S1.0760.95
164_A169_R1.0750.95
153_L161_F1.0730.95
154_S162_L1.0710.95
277_Q280_L1.0690.95
656_T660_E1.0690.95
413_T416_A1.0680.95
297_E301_E1.0670.95
538_E542_L1.0660.95
571_R575_Q1.0660.95
342_Q346_Q1.0660.95
159_A163_N1.0660.95
346_Q349_N1.0640.95
625_I632_I1.0590.95
801_T804_A1.0580.95
210_V225_L1.0570.95
737_Q740_D1.0560.95
358_F362_N1.0550.95
836_H840_R1.0540.95
872_Q876_Q1.0530.95
33_F994_L1.0490.94
685_T688_Q1.0490.94
416_A420_E1.0480.94
320_L324_M1.0470.94
69_N72_M1.0470.94
790_E793_R1.0470.94
955_E984_E1.0470.94
564_E571_R1.0460.94
304_A307_A1.0460.94
316_V319_R1.0450.94
474_T481_K1.0450.94
218_V224_S1.0440.94
388_Q391_H1.0440.94
800_V804_A1.0440.94
128_K131_D1.0440.94
645_L648_T1.0430.94
738_Q742_L1.0410.94
637_Q640_E1.0410.94
403_T407_T1.0410.94
603_D607_E1.0350.94
660_E663_E1.0330.94
253_D257_Q1.0320.94
986_F1000_A1.0320.94
758_L761_S1.0310.94
280_L284_S1.0290.94
220_S227_V1.0280.94
270_L284_S1.0270.94
559_Q563_D1.0270.94
52_L72_M1.0250.94
687_L691_I1.0210.94
531_R538_E1.0180.94
545_E548_T1.0170.93
464_N467_R1.0170.93
203_L207_A1.0170.93
492_T499_Q1.0160.93
964_A985_G1.0160.93
420_E424_L1.0150.93
605_Q608_H1.0130.93
591_T594_P1.0120.93
808_A811_Q1.0120.93
310_R317_N1.0100.93
601_W608_H1.0100.93
394_Q398_A1.0090.93
914_Q969_D1.0090.93
968_S1017_V1.0080.93
596_D599_Q1.0080.93
736_L743_A1.0070.93
146_R977_I1.0040.93
210_V220_S1.0040.93
726_C730_H1.0030.93
490_I494_E1.0020.93
957_F988_T1.0020.93
714_V718_N1.0020.93
154_S1009_K1.0010.93
711_E715_V1.0010.93
292_L296_W1.0010.93
936_V941_Q1.0000.93
636_Q643_Q0.9990.93
155_Q953_G0.9990.93
784_Q787_Q0.9980.93
414_A418_H0.9980.93
34_A48_D0.9960.93
243_Q247_N0.9940.93
747_L751_Q0.9940.93
632_I636_Q0.9920.93
203_L210_V0.9880.92
881_G885_S0.9880.92
496_Q499_Q0.9870.92
445_L448_A0.9870.92
398_A401_A0.9860.92
968_S1019_A0.9860.92
258_E261_R0.9860.92
11_L52_L0.9850.92
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359_R363_N0.6020.61
219_Q226_Q0.6020.61
489_R495_A0.6020.61
466_M475_Q0.6020.61
137_A143_D0.6010.61
143_D146_R0.6010.61
961_L998_L0.6010.61
733_Q737_Q0.6010.61
298_R302_H0.5990.61
84_E91_A0.5990.61
158_F1012_G0.5990.61
497_R504_Q0.5990.61
382_L401_A0.5990.61
493_L501_Q0.5980.60
142_L147_F0.5980.60
722_V726_C0.5970.60
225_L232_E0.5970.60
399_L402_I0.5960.60
320_L327_R0.5960.60
994_L1019_A0.5960.60
483_I486_Q0.5950.60
206_Q209_G0.5950.60
986_F1021_K0.5950.60
297_E304_A0.5940.60
596_D600_P0.5940.60
51_C980_L0.5940.60
393_E402_I0.5940.60
142_L153_L0.5930.60
548_T552_Q0.5920.60
293_R304_A0.5910.60
391_H402_I0.5910.60
350_T353_Q0.5900.59
73_T79_C0.5900.59
293_R300_A0.5900.59
714_V720_R0.5900.59
937_V940_W0.5890.59
14_L177_T0.5890.59
414_A417_Q0.5880.59
3_I964_A0.5880.59
39_T42_G0.5880.59
147_F980_L0.5880.59
56_H73_T0.5870.59
1017_V1021_K0.5870.59
393_E397_N0.5860.59
203_L866_L0.5860.59
829_Q833_A0.5850.59
918_L966_A0.5850.59
480_V483_I0.5840.59
173_L908_V0.5840.59
40_G953_G0.5830.59
152_L179_T0.5830.59
642_R650_L0.5820.58
125_L132_K0.5820.58
868_Q871_A0.5820.58
142_L977_I0.5820.58
52_L59_P0.5820.58
45_T52_L0.5810.58
147_F156_G0.5810.58
718_N722_V0.5810.58
370_A374_Q0.5810.58
1025_P1028_I0.5810.58
11_L161_F0.5800.58
495_A500_L0.5800.58
718_N725_Q0.5800.58
171_E176_L0.5800.58
233_K237_T0.5800.58
915_L938_D0.5790.58
487_E490_I0.5790.58
304_A311_Q0.5790.58
70_D116_L0.5790.58
155_Q166_P0.5780.58
39_T146_R0.5780.58
471_K475_Q0.5780.58
435_I438_Q0.5780.58
852_Q856_D0.5780.58
191_E195_S0.5770.58
985_G997_A0.5760.58
382_L386_Q0.5750.57
457_T460_N0.5740.57
36_T980_L0.5720.57
459_R463_L0.5720.57
955_E1014_I0.5720.57
477_L480_V0.5720.57
45_T55_Y0.5710.57
291_N295_H0.5710.57
176_L904_L0.5700.57
631_Q646_L0.5700.57
142_L904_L0.5700.57
971_V1009_K0.5700.57
164_A980_L0.5700.57
576_A579_Q0.5690.57
1004_L1016_H0.5690.57
40_G155_Q0.5680.57
586_A590_I0.5680.57
251_R255_L0.5680.57
301_E306_L0.5680.57
50_I54_L0.5670.56
828_I832_L0.5660.56
174_E958_L0.5660.56
352_L356_D0.5660.56
743_A750_A0.5660.56
994_L998_L0.5660.56
222_T227_V0.5660.56
157_Q169_R0.5650.56
382_L385_W0.5650.56
539_V549_L0.5640.56
643_Q649_T0.5640.56
334_A341_L0.5630.56
155_Q1014_I0.5630.56
380_E387_Q0.5630.56
915_L968_S0.5620.56
968_S1009_K0.5620.56
729_L733_Q0.5620.56
436_V440_K0.5620.56
478_A482_T0.5620.56
980_L985_G0.5610.56
1021_K1027_Q0.5610.56
160_A172_L0.5610.56
256_Q260_S0.5610.56
586_A589_N0.5610.56
978_D1011_I0.5600.55
14_L52_L0.5580.55
147_F180_E0.5580.55
794_R802_Q0.5580.55
448_A469_R0.5580.55
357_R360_Q0.5570.55
472_E475_Q0.5560.55
932_L1017_V0.5550.55
223_A228_L0.5550.55
723_H727_L0.5550.55
321_Q324_M0.5550.55
39_T1010_T0.5550.55
142_L174_E0.5550.55
621_L646_L0.5550.55
934_V939_T0.5550.55
948_T993_T0.5540.55
50_I55_Y0.5540.55
396_L400_A0.5540.55
938_D986_F0.5540.55
39_T43_K0.5530.55
908_V964_A0.5530.55
918_L962_A0.5530.55
948_T978_D0.5530.55
50_I83_V0.5520.54
589_N594_P0.5520.54
12_N979_S0.5520.54
943_D955_E0.5520.54
55_Y911_A0.5510.54
580_Q584_V0.5510.54
964_A1012_G0.5510.54
45_T70_D0.5510.54
218_V232_E0.5500.54
38_P993_T0.5500.54
207_A918_L0.5500.54
931_A935_E0.5490.54
932_L935_E0.5480.54
903_T959_V0.5470.54
538_E545_E0.5470.54
1011_I1017_V0.5470.54
193_H877_V0.5470.54
542_L548_T0.5470.54
460_N475_Q0.5470.54
31_G100_R0.5460.54
159_A956_S0.5460.54
48_D146_R0.5460.54
933_E937_V0.5440.53
31_G60_R0.5440.53
34_A922_Y0.5440.53
41_A980_L0.5440.53
543_G550_R0.5440.53
793_R797_Q0.5440.53
964_A988_T0.5420.53
33_F911_A0.5420.53
154_S173_L0.5420.53
10_N177_T0.5420.53
994_L1000_A0.5410.53
672_Q675_Q0.5410.53
589_N599_Q0.5410.53
52_L170_A0.5400.53
380_E383_R0.5400.53
293_R303_S0.5400.53
911_A922_Y0.5400.53
866_L870_I0.5380.53
983_D990_D0.5380.53
980_L1027_Q0.5370.52
852_Q862_Q0.5360.52
10_N186_S0.5360.52
10_N1028_I0.5360.52
14_L96_W0.5360.52
831_E835_T0.5360.52
582_Q585_T0.5350.52
487_E491_K0.5350.52
959_V969_D0.5350.52
163_N169_R0.5340.52
239_Q246_L0.5340.52
638_Q641_Q0.5340.52
552_Q555_A0.5330.52
910_L913_Q0.5330.52
256_Q259_A0.5330.52
721_Q724_E0.5320.52
810_H815_P0.5320.52
378_D387_Q0.5320.52
51_C56_H0.5320.52
40_G43_K0.5320.52
331_R334_A0.5320.52
883_L886_L0.5320.52
395_K401_A0.5310.52
300_A304_A0.5310.52
948_T964_A0.5310.52
78_E97_S0.5310.52
153_L915_L0.5300.52
175_E185_I0.5290.51
319_R344_Q0.5280.51
964_A971_V0.5280.51
981_F1014_I0.5270.51
490_I493_L0.5270.51
116_L971_V0.5260.51
683_E690_R0.5260.51
465_E468_Q0.5250.51
554_D558_K0.5250.51
154_S948_T0.5250.51
960_S984_E0.5240.51
176_L950_T0.5240.51
579_Q583_A0.5240.51
965_L1029_K0.5240.51
475_Q483_I0.5230.51
783_E796_A0.5230.51
664_E669_T0.5220.50
991_S1032_K0.5220.50
191_E194_K0.5210.50
161_F934_V0.5210.50
807_L811_Q0.5210.50
911_A964_A0.5200.50
51_C1015_S0.5190.50
964_A1009_K0.5180.50
785_L788_N0.5180.50
12_N72_M0.5170.50
573_D577_L0.5170.50
397_N402_I0.5170.50
381_H385_W0.5170.50
153_L1002_D0.5160.50
45_T69_N0.5160.50
488_A498_A0.5160.50
44_T49_A0.5160.50
11_L943_D0.5150.50
293_R306_L0.5150.50
154_S170_A0.5150.50
212_L223_A0.5140.49
243_Q246_L0.5140.49
946_R985_G0.5130.49
21_D162_L0.5130.49
932_L997_A0.5130.49
322_S330_I0.5120.49
804_A809_Q0.5120.49
694_L708_P0.5120.49
994_L1005_N0.5120.49
997_A1011_I0.5110.49
389_L397_N0.5110.49
73_T907_L0.5110.49
482_T486_Q0.5100.49
635_Y649_T0.5100.49
47_L59_P0.5100.49
707_L710_C0.5100.49
935_E959_V0.5100.49
726_C737_Q0.5090.49
958_L996_T0.5090.49
59_P160_A0.5090.49
157_Q163_N0.5080.49
978_D986_F0.5080.49
47_L179_T0.5080.49
858_D861_Q0.5080.49
964_A1004_L0.5080.49
44_T60_R0.5070.48
493_L498_A0.5070.48
98_Q146_R0.5060.48
988_T1021_K0.5060.48
911_A1009_K0.5060.48
41_A988_T0.5060.48
1033_I1040_K0.5060.48
140_T154_S0.5060.48
22_F934_V0.5060.48
703_Q708_P0.5050.48
946_R957_F0.5050.48
186_S189_V0.5050.48
908_V1004_L0.5040.48
231_E234_Q0.5040.48
541_K544_E0.5040.48
11_L94_A0.5030.48
681_Q684_L0.5030.48
575_Q579_Q0.5030.48
96_W907_L0.5020.48
161_F173_L0.5020.48
1000_A1004_L0.5020.48
494_E502_A0.5020.48
994_L1011_I0.5020.48
152_L157_Q0.5000.48
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4ux3A 1 0.4027 100 0.695 Contact Map
3auyA 2 0.3492 100 0.719 Contact Map
3zgxA 2 0.3168 100 0.721 Contact Map
4ad8A 1 0.3931 100 0.743 Contact Map
3qf7A 2 0.3368 100 0.753 Contact Map
1w1wA 2 0.3053 100 0.759 Contact Map
3qksA 1 0.187 100 0.799 Contact Map
3qktA 2 0.3206 100 0.801 Contact Map
4i99A 2 0.2929 100 0.802 Contact Map
4abyA 1 0.3225 100 0.808 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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