SBCC - ECOLI - GREMLIN Contacts

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SBCC - Nuclease SbcCD subunit C

UniProt:	P13458	Sequences: MKILSLRLKNLNSLKGEWKIDFTREPFASNGLFAITGPTGAGKTTLLDAICLALYHETPRLSNVSQSQNDLMTRDTAECLAEVEFEVKGEAYRAFWSQNRARNQPDGNLQVPRVELARCADGKILADKVKDKLELTATLTGLDYGRFTRSMLLSQGQFAAFLNAKPKERAELLEELTGTEIYGQISAMVFEQHKSARTELEKLQAQASGVTLLTPEQVQSLTASLQVLTDEEKQLITAQQQEQQSLNWLTRQDELQQEASRRQQALQQALAEEEKAQPQLAALSLAQPARNLRPHWERIAEHSAALAHIRQQIEEVNTRLQSTMALRASIRHHAAKQSAELQQQQQSLNTWLQEHDRFRQWNNEPAGWRAQFSQQTSDREHLRQWQQQLTHAEQKLNALAAITLTLTADEVATALAQHAEQRPLRQHLVALHGQIVPQQKRLAQLQVAIQNVTQEQTQRNAALNEMRQRYKEKTQQLADVKTICEQEARIKTLEAQRAQLQAGQPCPLCGSTSHPAVEAYQALEPGVNQSRLLALENEVKKLGEEGATLRGQLDAITKQLQRDENEAQSLRQDEQALTQQWQAVTASLNITLQPLDDIQPWLDAQDEHERQLRLLSQRHELQGQIAAHNQQIIQYQQQIEQRQQLLLTTLTGYALTLPQEDEEESWLATRQQEAQSWQQRQNELTALQNRIQQLTPILETLPQSDELPHCEETVVLENWRQVHEQCLALHSQQQTLQQQDVLAAQSLQKAQAQFDTALQASVFDDQQAFLAALMDEQTLTQLEQLKQNLENQRRQAQTLVTQTAETLAQHQQHRPDDGLALTVTVEQIQQELAQTHQKLRENTTSQGEIRQQLKQDADNRQQQQTLMQQIAQMTQQVEDWGYLNSLIGSKEGDKFRKFAQGLTLDNLVHLANQQLTRLHGRYLLQRKASEALEVEVVDTWQADAVRDTRTLSGGESFLVSLALALALSDLVSHKTRIDSLFLDEGFGTLDSETLDTALDALDALNASGKTIGVISHVEAMKERIPVQIKVKKINGLGYSKLESTFAVK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10927
Length:	1048 (955)
Sequences:	2850 (2624)
Seq/√Len:	84.9

ECOLI - SBCC
BACSU - SBCC SMC YHAN
HALSA - Q9HS95 RAD50
SULSO - RAD50

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
82_E	95_F	3.294	1.00
894_K	898_F	3.281	1.00
917_R	1003_A	3.236	1.00
480_V	484_C	3.195	1.00
342_Q	345_Q	3.166	1.00
261_R	265_A	3.148	1.00
335_A	338_S	3.054	1.00
217_Q	228_L	2.960	1.00
272_E	275_K	2.959	1.00
594_P	597_D	2.787	1.00
725_Q	728_A	2.752	1.00
824_T	827_Q	2.677	1.00
217_Q	221_L	2.651	1.00
649_T	652_G	2.645	1.00
135_L	138_T	2.627	1.00
303_S	310_R	2.617	1.00
217_Q	220_S	2.603	1.00
82_E	93_R	2.585	1.00
344_Q	347_S	2.571	1.00
296_W	303_S	2.524	1.00
224_S	228_L	2.523	1.00
438_Q	442_L	2.469	1.00
933_E	938_D	2.468	1.00
474_T	478_A	2.440	1.00
459_R	462_A	2.433	1.00
463_L	466_M	2.426	1.00
575_Q	578_T	2.415	1.00
569_S	573_D	2.397	1.00
225_L	228_L	2.370	1.00
776_E	780_T	2.360	1.00
541_K	545_E	2.353	1.00
531_R	535_L	2.334	1.00
235_L	239_Q	2.333	1.00
932_L	938_D	2.308	1.00
534_A	538_E	2.306	1.00
236_I	239_Q	2.298	1.00
298_R	301_E	2.288	1.00
322_S	326_L	2.287	1.00
653_Y	657_L	2.262	1.00
277_Q	284_S	2.243	1.00
218_V	228_L	2.239	1.00
716_L	720_R	2.237	1.00
501_Q	504_Q	2.237	1.00
709_H	713_T	2.229	1.00
473_K	476_Q	2.219	1.00
270_L	277_Q	2.216	1.00
751_Q	755_D	2.177	1.00
303_S	306_L	2.155	1.00
197_R	201_E	2.151	1.00
601_W	604_A	2.149	1.00
713_T	717_E	2.149	1.00
5_S	19_K	2.143	1.00
702_P	706_E	2.121	1.00
7_R	17_E	2.119	1.00
721_Q	725_Q	2.095	1.00
259_A	263_Q	2.094	1.00
663_E	666_W	2.072	1.00
636_Q	640_E	2.066	1.00
786_K	789_L	2.061	1.00
562_R	566_E	2.056	1.00
781_Q	785_L	2.056	1.00
231_E	235_L	2.054	1.00
3_I	83_V	2.043	1.00
580_Q	583_A	2.039	1.00
931_A	938_D	2.038	1.00
267_Q	270_L	2.036	1.00
234_Q	238_A	2.032	1.00
730_H	734_Q	2.031	1.00
7_R	82_E	2.015	1.00
648_T	652_G	1.999	1.00
364_E	368_W	1.998	1.00
831_E	834_Q	1.986	1.00
366_A	369_R	1.986	1.00
360_Q	364_E	1.985	1.00
397_N	401_A	1.982	1.00
269_A	273_E	1.977	1.00
444_Q	448_A	1.974	1.00
328_A	331_R	1.971	1.00
803_T	810_H	1.966	1.00
895_F	898_F	1.956	1.00
460_N	464_N	1.956	1.00
309_I	313_I	1.954	1.00
48_D	162_L	1.952	1.00
254_E	258_E	1.950	1.00
4_L	91_A	1.935	1.00
932_L	936_V	1.932	1.00
931_A	936_V	1.921	1.00
296_W	300_A	1.919	1.00
493_L	497_R	1.917	1.00
492_T	495_A	1.911	1.00
871_A	875_Q	1.909	1.00
272_E	276_A	1.909	1.00
604_A	608_H	1.901	1.00
737_Q	744_A	1.894	1.00
799_L	802_Q	1.892	1.00
359_R	362_N	1.884	1.00
385_W	388_Q	1.883	1.00
281_A	284_S	1.876	1.00
300_A	303_S	1.871	1.00
647_L	650_L	1.865	1.00
388_Q	392_A	1.858	1.00
157_Q	160_A	1.855	1.00
552_Q	556_I	1.852	1.00
326_L	330_I	1.849	1.00
529_Q	533_L	1.844	1.00
279_Q	282_A	1.839	1.00
837_Q	841_E	1.831	1.00
736_L	739_Q	1.827	1.00
650_L	654_A	1.807	1.00
441_R	444_Q	1.801	1.00
500_L	503_G	1.800	1.00
481_K	485_E	1.794	1.00
443_A	446_Q	1.793	1.00
662_E	666_W	1.791	1.00
86_E	89_G	1.785	1.00
704_S	708_P	1.778	1.00
741_V	745_Q	1.775	1.00
477_L	481_K	1.768	1.00
293_R	296_W	1.759	1.00
351_W	354_E	1.756	1.00
497_R	500_L	1.750	1.00
489_R	492_T	1.738	1.00
385_W	389_L	1.735	1.00
659_Q	662_E	1.735	1.00
421_Q	425_R	1.732	1.00
455_E	458_Q	1.731	1.00
46_L	1030_V	1.728	1.00
542_L	546_G	1.727	1.00
461_A	465_E	1.721	1.00
337_Q	340_E	1.721	1.00
251_R	254_E	1.719	1.00
390_T	393_E	1.714	1.00
220_S	228_L	1.711	1.00
325_A	329_S	1.708	1.00
778_T	781_Q	1.707	1.00
783_E	787_Q	1.705	1.00
311_Q	315_E	1.702	1.00
221_L	228_L	1.700	1.00
489_R	493_L	1.689	1.00
718_N	721_Q	1.681	1.00
642_R	645_L	1.677	1.00
369_R	372_F	1.676	1.00
739_Q	742_L	1.669	1.00
395_K	398_A	1.668	1.00
751_Q	754_F	1.668	1.00
217_Q	225_L	1.664	1.00
493_L	496_Q	1.662	1.00
855_Q	858_D	1.656	1.00
7_R	19_K	1.651	1.00
1013_V	1020_M	1.651	1.00
270_L	273_E	1.648	1.00
629_N	633_I	1.648	1.00
705_D	709_H	1.639	1.00
639_I	643_Q	1.632	1.00
221_L	225_L	1.630	1.00
623_G	627_A	1.628	1.00
671_Q	675_Q	1.620	1.00
228_L	232_E	1.619	1.00
221_L	224_S	1.619	1.00
307_A	310_R	1.613	1.00
263_Q	267_Q	1.612	1.00
401_A	404_L	1.612	1.00
6_L	22_F	1.611	1.00
627_A	631_Q	1.608	1.00
332_H	336_K	1.607	1.00
499_Q	503_G	1.603	1.00
556_I	559_Q	1.603	1.00
643_Q	647_L	1.601	1.00
22_F	1012_G	1.600	1.00
392_A	396_L	1.595	1.00
496_Q	500_L	1.593	1.00
893_D	897_K	1.591	1.00
655_L	659_Q	1.590	1.00
933_E	940_W	1.586	1.00
402_I	406_L	1.579	1.00
905_D	926_R	1.574	1.00
588_L	591_T	1.573	1.00
590_I	594_P	1.566	1.00
536_E	540_K	1.564	1.00
932_L	940_W	1.559	1.00
9_K	17_E	1.549	1.00
864_Q	868_Q	1.549	1.00
706_E	709_H	1.549	1.00
329_S	333_H	1.547	1.00
530_S	534_A	1.546	1.00
599_Q	603_D	1.543	1.00
315_E	319_R	1.542	1.00
740_D	744_A	1.537	1.00
265_A	268_Q	1.536	1.00
225_L	229_T	1.532	1.00
538_E	541_K	1.530	1.00
384_Q	388_Q	1.525	1.00
80_L	97_S	1.523	1.00
938_D	941_Q	1.521	1.00
312_Q	316_V	1.518	1.00
931_A	939_T	1.518	1.00
744_A	748_Q	1.514	1.00
600_P	604_A	1.513	1.00
327_R	331_R	1.511	1.00
796_A	799_L	1.510	1.00
806_T	810_H	1.509	0.99
232_E	236_I	1.507	0.99
986_F	1017_V	1.506	0.99
932_L	939_T	1.505	0.99
901_G	905_D	1.500	0.99
218_V	222_T	1.498	0.99
389_L	393_E	1.496	0.99
318_T	322_S	1.494	0.99
476_Q	479_D	1.486	0.99
443_A	447_V	1.484	0.99
439_Q	443_A	1.483	0.99
420_E	423_P	1.474	0.99
936_V	939_T	1.465	0.99
252_Q	256_Q	1.465	0.99
318_T	321_Q	1.464	0.99
404_L	407_T	1.462	0.99
690_R	693_Q	1.460	0.99
473_K	477_L	1.458	0.99
857_A	861_Q	1.457	0.99
686_A	690_R	1.456	0.99
892_G	896_R	1.452	0.99
242_E	246_L	1.451	0.99
356_D	359_R	1.450	0.99
232_E	238_A	1.450	0.99
626_A	629_N	1.444	0.99
217_Q	227_V	1.440	0.99
960_S	967_L	1.437	0.99
958_L	993_T	1.436	0.99
667_L	670_R	1.435	0.99
717_E	721_Q	1.434	0.99
931_A	940_W	1.433	0.99
549_L	553_L	1.431	0.99
274_E	277_Q	1.426	0.99
361_W	364_E	1.424	0.99
440_K	444_Q	1.423	0.99
730_H	733_Q	1.423	0.99
496_Q	504_Q	1.420	0.99
466_M	470_Y	1.417	0.99
475_Q	478_A	1.415	0.99
362_N	366_A	1.413	0.99
500_L	504_Q	1.409	0.99
469_R	472_E	1.404	0.99
834_Q	838_K	1.403	0.99
704_S	707_L	1.401	0.99
263_Q	270_L	1.401	0.99
11_L	63_N	1.401	0.99
466_M	469_R	1.390	0.99
392_A	395_K	1.385	0.99
685_T	689_N	1.385	0.99
493_L	500_L	1.383	0.99
748_Q	755_D	1.382	0.99
699_E	703_Q	1.382	0.99
870_I	874_T	1.382	0.99
81_A	96_W	1.380	0.99
561_Q	564_E	1.379	0.99
347_S	350_T	1.372	0.99
807_L	812_Q	1.371	0.99
488_A	492_T	1.370	0.99
428_L	432_H	1.369	0.99
707_L	711_E	1.369	0.99
640_E	643_Q	1.369	0.99
389_L	392_A	1.367	0.99
734_Q	737_Q	1.366	0.99
496_Q	503_G	1.366	0.99
199_E	202_K	1.363	0.99
694_L	698_L	1.361	0.99
620_E	624_Q	1.359	0.99
217_Q	224_S	1.359	0.99
276_A	279_Q	1.355	0.99
362_N	365_P	1.351	0.99
333_H	336_K	1.349	0.99
31_G	169_R	1.348	0.99
301_E	305_A	1.345	0.99
706_E	710_C	1.338	0.99
266_L	270_L	1.338	0.99
314_E	317_N	1.336	0.99
305_A	308_H	1.335	0.99
94_A	132_K	1.333	0.99
800_V	810_H	1.326	0.99
495_A	499_Q	1.326	0.99
246_L	250_T	1.323	0.99
427_H	430_A	1.321	0.99
787_Q	790_E	1.319	0.99
328_A	332_H	1.318	0.99
147_F	154_S	1.317	0.99
1002_D	1023_R	1.317	0.99
162_L	173_L	1.314	0.99
573_D	576_A	1.311	0.99
268_Q	272_E	1.311	0.99
736_L	740_D	1.310	0.99
255_L	259_A	1.310	0.99
349_N	352_L	1.309	0.99
399_L	403_T	1.309	0.99
396_L	399_L	1.307	0.99
417_Q	421_Q	1.304	0.99
165_K	168_E	1.303	0.99
303_S	307_A	1.303	0.99
219_Q	222_T	1.301	0.98
788_N	792_Q	1.299	0.98
533_L	537_N	1.297	0.98
398_A	402_I	1.296	0.98
478_A	481_K	1.295	0.98
275_K	279_Q	1.294	0.98
236_I	240_Q	1.294	0.98
977_I	986_F	1.292	0.98
540_K	543_G	1.288	0.98
695_T	699_E	1.286	0.98
314_E	318_T	1.286	0.98
343_Q	347_S	1.285	0.98
447_V	451_N	1.281	0.98
200_L	207_A	1.281	0.98
429_V	432_H	1.280	0.98
269_A	272_E	1.278	0.98
603_D	606_D	1.278	0.98
542_L	545_E	1.277	0.98
394_Q	397_N	1.276	0.98
787_Q	791_N	1.276	0.98
583_A	587_S	1.272	0.98
232_E	239_Q	1.272	0.98
441_R	445_L	1.271	0.98
664_E	668_A	1.269	0.98
200_L	209_G	1.265	0.98
563_D	566_E	1.264	0.98
585_T	589_N	1.263	0.98
807_L	810_H	1.263	0.98
921_R	939_T	1.261	0.98
80_L	95_F	1.261	0.98
948_T	956_S	1.258	0.98
811_Q	814_R	1.257	0.98
479_D	483_I	1.255	0.98
67_S	70_D	1.255	0.98
471_K	474_T	1.254	0.98
276_A	280_L	1.254	0.98
147_F	158_F	1.253	0.98
333_H	337_Q	1.250	0.98
634_Q	638_Q	1.247	0.98
319_R	323_T	1.246	0.98
12_N	45_T	1.246	0.98
324_M	328_A	1.244	0.98
732_Q	735_T	1.244	0.98
545_E	549_L	1.243	0.98
239_Q	832_L	1.242	0.98
395_K	399_L	1.242	0.98
346_Q	350_T	1.240	0.98
470_Y	473_K	1.239	0.98
661_D	664_E	1.235	0.98
860_R	864_Q	1.235	0.98
312_Q	315_E	1.234	0.98
753_Q	756_T	1.234	0.98
957_F	986_F	1.234	0.98
296_W	310_R	1.233	0.98
700_T	704_S	1.233	0.98
568_Q	571_R	1.232	0.98
405_T	408_A	1.232	0.98
427_H	431_L	1.231	0.98
810_H	814_R	1.226	0.98
4_L	86_E	1.226	0.98
666_W	670_R	1.226	0.98
597_D	601_W	1.221	0.98
311_Q	318_T	1.220	0.98
257_Q	260_S	1.219	0.98
933_E	941_Q	1.218	0.98
688_Q	692_Q	1.218	0.98
964_A	986_F	1.217	0.98
693_Q	696_P	1.217	0.98
835_T	839_L	1.217	0.98
492_T	497_R	1.216	0.98
467_R	471_K	1.215	0.98
750_A	753_Q	1.215	0.98
383_R	386_Q	1.214	0.98
492_T	496_Q	1.210	0.98
739_Q	743_A	1.208	0.98
393_E	401_A	1.206	0.98
422_R	426_Q	1.203	0.97
644_Q	648_T	1.202	0.97
699_E	702_P	1.201	0.97
663_E	667_L	1.201	0.97
802_Q	806_T	1.200	0.97
957_F	987_G	1.200	0.97
315_E	318_T	1.199	0.97
353_Q	356_D	1.198	0.97
803_T	806_T	1.197	0.97
786_K	790_E	1.193	0.97
866_L	869_Q	1.193	0.97
238_A	831_E	1.191	0.97
458_Q	462_A	1.190	0.97
365_P	369_R	1.188	0.97
307_A	311_Q	1.188	0.97
553_L	557_T	1.187	0.97
624_Q	627_A	1.187	0.97
844_T	848_E	1.184	0.97
557_T	561_Q	1.181	0.97
456_Q	459_R	1.178	0.97
497_R	503_G	1.175	0.97
369_R	373_S	1.175	0.97
293_R	297_E	1.175	0.97
451_N	455_E	1.174	0.97
203_L	206_Q	1.174	0.97
988_T	1017_V	1.173	0.97
492_T	500_L	1.172	0.97
606_D	610_R	1.172	0.97
961_L	1015_S	1.170	0.97
84_E	93_R	1.169	0.97
668_A	671_Q	1.167	0.97
496_Q	502_A	1.166	0.97
626_A	630_Q	1.165	0.97
737_Q	741_V	1.162	0.97
476_Q	480_V	1.159	0.97
645_L	649_T	1.158	0.97
52_L	70_D	1.158	0.97
742_L	746_S	1.157	0.97
557_T	564_E	1.157	0.97
637_Q	641_Q	1.157	0.97
469_R	476_Q	1.156	0.97
430_A	434_Q	1.154	0.97
202_K	205_A	1.154	0.97
622_Q	626_A	1.152	0.97
157_Q	968_S	1.150	0.97
334_A	338_S	1.150	0.97
635_Y	639_I	1.150	0.97
326_L	329_S	1.148	0.97
619_H	622_Q	1.148	0.97
434_Q	438_Q	1.147	0.97
976_R	980_L	1.145	0.97
933_E	939_T	1.141	0.97
953_G	984_E	1.139	0.96
570_L	574_E	1.138	0.96
442_L	446_Q	1.137	0.96
652_G	655_L	1.136	0.96
386_Q	390_T	1.135	0.96
985_G	1017_V	1.133	0.96
347_S	351_W	1.133	0.96
470_Y	477_L	1.131	0.96
273_E	277_Q	1.131	0.96
207_A	210_V	1.125	0.96
154_S	157_Q	1.122	0.96
998_L	1017_V	1.117	0.96
271_A	275_K	1.116	0.96
450_Q	454_Q	1.116	0.96
354_E	357_R	1.116	0.96
660_E	664_E	1.116	0.96
697_I	701_L	1.116	0.96
544_E	548_T	1.115	0.96
462_A	466_M	1.113	0.96
550_R	554_D	1.112	0.96
372_F	375_Q	1.111	0.96
693_Q	697_I	1.109	0.96
795_Q	799_L	1.109	0.96
933_E	936_V	1.109	0.96
336_K	340_E	1.108	0.96
465_E	469_R	1.107	0.96
259_A	262_R	1.103	0.96
493_L	502_A	1.102	0.96
190_F	194_K	1.100	0.96
779_L	783_E	1.100	0.96
869_Q	872_Q	1.099	0.96
79_C	98_Q	1.096	0.96
387_Q	391_H	1.096	0.96
535_L	539_V	1.095	0.96
310_R	318_T	1.091	0.96
337_Q	341_L	1.090	0.95
805_E	808_A	1.090	0.95
101_A	113_R	1.090	0.95
159_A	162_L	1.090	0.95
237_T	241_Q	1.089	0.95
235_L	238_A	1.088	0.95
299_I	303_S	1.088	0.95
683_E	686_A	1.085	0.95
654_A	657_L	1.084	0.95
341_L	345_Q	1.083	0.95
856_D	860_R	1.080	0.95
647_L	651_T	1.077	0.95
220_S	224_S	1.076	0.95
164_A	169_R	1.075	0.95
153_L	161_F	1.073	0.95
154_S	162_L	1.071	0.95
277_Q	280_L	1.069	0.95
656_T	660_E	1.069	0.95
413_T	416_A	1.068	0.95
297_E	301_E	1.067	0.95
538_E	542_L	1.066	0.95
571_R	575_Q	1.066	0.95
342_Q	346_Q	1.066	0.95
159_A	163_N	1.066	0.95
346_Q	349_N	1.064	0.95
625_I	632_I	1.059	0.95
801_T	804_A	1.058	0.95
210_V	225_L	1.057	0.95
737_Q	740_D	1.056	0.95
358_F	362_N	1.055	0.95
836_H	840_R	1.054	0.95
872_Q	876_Q	1.053	0.95
33_F	994_L	1.049	0.94
685_T	688_Q	1.049	0.94
416_A	420_E	1.048	0.94
320_L	324_M	1.047	0.94
69_N	72_M	1.047	0.94
790_E	793_R	1.047	0.94
955_E	984_E	1.047	0.94
564_E	571_R	1.046	0.94
304_A	307_A	1.046	0.94
316_V	319_R	1.045	0.94
474_T	481_K	1.045	0.94
218_V	224_S	1.044	0.94
388_Q	391_H	1.044	0.94
800_V	804_A	1.044	0.94
128_K	131_D	1.044	0.94
645_L	648_T	1.043	0.94
738_Q	742_L	1.041	0.94
637_Q	640_E	1.041	0.94
403_T	407_T	1.041	0.94
603_D	607_E	1.035	0.94
660_E	663_E	1.033	0.94
253_D	257_Q	1.032	0.94
986_F	1000_A	1.032	0.94
758_L	761_S	1.031	0.94
280_L	284_S	1.029	0.94
220_S	227_V	1.028	0.94
270_L	284_S	1.027	0.94
559_Q	563_D	1.027	0.94
52_L	72_M	1.025	0.94
687_L	691_I	1.021	0.94
531_R	538_E	1.018	0.94
545_E	548_T	1.017	0.93
464_N	467_R	1.017	0.93
203_L	207_A	1.017	0.93
492_T	499_Q	1.016	0.93
964_A	985_G	1.016	0.93
420_E	424_L	1.015	0.93
605_Q	608_H	1.013	0.93
591_T	594_P	1.012	0.93
808_A	811_Q	1.012	0.93
310_R	317_N	1.010	0.93
601_W	608_H	1.010	0.93
394_Q	398_A	1.009	0.93
914_Q	969_D	1.009	0.93
968_S	1017_V	1.008	0.93
596_D	599_Q	1.008	0.93
736_L	743_A	1.007	0.93
146_R	977_I	1.004	0.93
210_V	220_S	1.004	0.93
726_C	730_H	1.003	0.93
490_I	494_E	1.002	0.93
957_F	988_T	1.002	0.93
714_V	718_N	1.002	0.93
154_S	1009_K	1.001	0.93
711_E	715_V	1.001	0.93
292_L	296_W	1.001	0.93
936_V	941_Q	1.000	0.93
636_Q	643_Q	0.999	0.93
155_Q	953_G	0.999	0.93
784_Q	787_Q	0.998	0.93
414_A	418_H	0.998	0.93
34_A	48_D	0.996	0.93
243_Q	247_N	0.994	0.93
747_L	751_Q	0.994	0.93
632_I	636_Q	0.992	0.93
203_L	210_V	0.988	0.92
881_G	885_S	0.988	0.92
496_Q	499_Q	0.987	0.92
445_L	448_A	0.987	0.92
398_A	401_A	0.986	0.92
968_S	1019_A	0.986	0.92
258_E	261_R	0.986	0.92
11_L	52_L	0.985	0.92
936_V	940_W	0.985	0.92
257_Q	261_R	0.985	0.92
792_Q	795_Q	0.985	0.92
98_Q	101_A	0.985	0.92
792_Q	796_A	0.984	0.92
277_Q	281_A	0.984	0.92
381_H	384_Q	0.984	0.92
734_Q	738_Q	0.984	0.92
338_S	342_Q	0.984	0.92
379_R	386_Q	0.984	0.92
154_S	1017_V	0.982	0.92
984_E	989_L	0.982	0.92
200_L	203_L	0.982	0.92
260_S	263_Q	0.982	0.92
289_A	303_S	0.981	0.92
73_T	76_T	0.980	0.92
492_T	504_Q	0.976	0.92
807_L	814_R	0.975	0.92
618_R	621_L	0.974	0.92
462_A	465_E	0.974	0.92
964_A	987_G	0.973	0.92
340_E	344_Q	0.972	0.92
629_N	636_Q	0.970	0.92
567_A	571_R	0.970	0.92
497_R	502_A	0.969	0.92
146_R	170_A	0.967	0.92
14_L	170_A	0.967	0.92
321_Q	325_A	0.966	0.92
358_F	361_W	0.966	0.92
641_Q	645_L	0.965	0.92
502_A	505_P	0.965	0.92
3_I	6_L	0.963	0.91
199_E	209_G	0.961	0.91
804_A	807_L	0.961	0.91
200_L	210_V	0.961	0.91
931_A	937_V	0.961	0.91
911_A	957_F	0.960	0.91
657_L	661_D	0.960	0.91
448_A	451_N	0.959	0.91
666_W	669_T	0.959	0.91
11_L	96_W	0.959	0.91
417_Q	420_E	0.958	0.91
157_Q	171_E	0.954	0.91
41_A	1017_V	0.953	0.91
69_N	73_T	0.950	0.91
595_L	599_Q	0.950	0.91
756_T	760_A	0.947	0.91
598_I	601_W	0.947	0.91
40_G	984_E	0.947	0.91
141_G	1004_L	0.946	0.91
169_R	172_L	0.945	0.91
894_K	897_K	0.945	0.91
218_V	226_Q	0.943	0.91
33_F	39_T	0.941	0.91
1000_A	1017_V	0.940	0.90
322_S	325_A	0.940	0.90
33_F	1012_G	0.940	0.90
309_I	312_Q	0.939	0.90
247_N	250_T	0.937	0.90
931_A	941_Q	0.937	0.90
970_L	977_I	0.935	0.90
12_N	39_T	0.934	0.90
651_T	655_L	0.933	0.90
449_I	452_V	0.933	0.90
915_L	960_S	0.931	0.90
390_T	394_Q	0.929	0.90
154_S	177_T	0.929	0.90
331_R	335_A	0.927	0.90
153_L	162_L	0.926	0.90
379_R	383_R	0.926	0.90
629_N	632_I	0.926	0.90
456_Q	460_N	0.923	0.90
652_G	656_T	0.922	0.90
391_H	394_Q	0.922	0.90
204_Q	208_S	0.920	0.90
226_Q	229_T	0.920	0.90
609_E	613_R	0.919	0.89
617_Q	620_E	0.917	0.89
784_Q	788_N	0.916	0.89
323_T	326_L	0.916	0.89
266_L	269_A	0.914	0.89
262_R	265_A	0.914	0.89
956_S	968_S	0.914	0.89
668_A	672_Q	0.913	0.89
799_L	803_T	0.913	0.89
154_S	158_F	0.912	0.89
630_Q	633_I	0.911	0.89
210_V	227_V	0.911	0.89
299_I	302_H	0.910	0.89
968_S	986_F	0.908	0.89
40_G	955_E	0.905	0.89
601_W	605_Q	0.905	0.89
264_Q	267_Q	0.903	0.89
370_A	373_S	0.903	0.89
907_L	970_L	0.903	0.89
546_G	550_R	0.901	0.89
488_A	493_L	0.901	0.89
697_I	700_T	0.900	0.88
222_T	225_L	0.898	0.88
187_A	190_F	0.898	0.88
957_F	985_G	0.897	0.88
195_S	199_E	0.896	0.88
729_L	732_Q	0.895	0.88
296_W	299_I	0.895	0.88
908_V	923_L	0.895	0.88
289_A	292_L	0.895	0.88
352_L	355_H	0.894	0.88
379_R	382_L	0.893	0.88
595_L	598_I	0.891	0.88
662_E	665_S	0.890	0.88
547_A	550_R	0.890	0.88
642_R	646_L	0.887	0.88
319_R	322_S	0.887	0.88
539_V	543_G	0.886	0.88
600_P	603_D	0.886	0.88
424_L	428_L	0.884	0.88
935_E	938_D	0.882	0.87
363_N	366_A	0.881	0.87
14_L	152_L	0.879	0.87
361_W	365_P	0.877	0.87
592_L	596_D	0.877	0.87
493_L	503_G	0.877	0.87
10_N	955_E	0.877	0.87
959_V	993_T	0.876	0.87
413_T	417_Q	0.876	0.87
772_A	775_D	0.874	0.87
350_T	354_E	0.873	0.87
317_N	321_Q	0.873	0.87
479_D	482_T	0.873	0.87
636_Q	639_I	0.870	0.87
794_R	797_Q	0.867	0.87
146_R	154_S	0.866	0.86
325_A	328_A	0.866	0.86
258_E	262_R	0.866	0.86
367_G	371_Q	0.862	0.86
628_H	632_I	0.860	0.86
919_H	924_L	0.860	0.86
986_F	1011_I	0.860	0.86
63_N	72_M	0.859	0.86
12_N	52_L	0.859	0.86
499_Q	505_P	0.858	0.86
559_Q	562_R	0.858	0.86
577_L	580_Q	0.857	0.86
37_G	42_G	0.857	0.86
423_P	427_H	0.855	0.86
893_D	896_R	0.854	0.86
47_L	169_R	0.854	0.86
415_L	418_H	0.853	0.86
587_S	590_I	0.852	0.86
988_T	1000_A	0.852	0.86
532_L	535_L	0.851	0.86
495_A	503_G	0.850	0.85
803_T	814_R	0.849	0.85
669_T	673_E	0.849	0.85
904_L	950_T	0.848	0.85
692_Q	696_P	0.848	0.85
392_A	399_L	0.846	0.85
982_L	1001_L	0.845	0.85
727_L	730_H	0.845	0.85
428_L	444_Q	0.845	0.85
640_E	644_Q	0.844	0.85
987_G	1017_V	0.843	0.85
720_R	723_H	0.842	0.85
768_A	772_A	0.841	0.85
827_Q	831_E	0.840	0.85
932_L	941_Q	0.840	0.85
241_Q	245_S	0.839	0.85
311_Q	322_S	0.836	0.84
382_L	389_L	0.836	0.84
365_P	368_W	0.836	0.84
64_V	69_N	0.834	0.84
218_V	225_L	0.834	0.84
705_D	712_E	0.834	0.84
624_Q	628_H	0.833	0.84
403_T	406_L	0.830	0.84
232_E	235_L	0.830	0.84
680_R	683_E	0.828	0.84
924_L	936_V	0.827	0.84
549_L	552_Q	0.827	0.84
300_A	311_Q	0.827	0.84
488_A	500_L	0.826	0.84
475_Q	480_V	0.826	0.84
745_Q	751_Q	0.826	0.84
206_Q	210_V	0.826	0.84
33_F	964_A	0.824	0.84
289_A	296_W	0.824	0.84
914_Q	918_L	0.824	0.84
389_L	396_L	0.824	0.84
780_T	784_Q	0.824	0.84
796_A	803_T	0.822	0.83
351_W	355_H	0.822	0.83
220_S	225_L	0.822	0.83
870_I	873_M	0.820	0.83
11_L	59_P	0.819	0.83
386_Q	389_L	0.818	0.83
982_L	985_G	0.816	0.83
957_F	968_S	0.815	0.83
828_I	835_T	0.815	0.83
958_L	1011_I	0.813	0.83
799_L	807_L	0.812	0.83
37_G	43_K	0.812	0.83
767_Q	770_L	0.812	0.83
586_A	598_I	0.811	0.83
397_N	400_A	0.811	0.83
177_T	186_S	0.810	0.83
268_Q	271_A	0.809	0.83
922_Y	968_S	0.809	0.83
438_Q	441_R	0.809	0.83
646_L	649_T	0.808	0.82
997_A	1017_V	0.808	0.82
14_L	179_T	0.807	0.82
290_R	293_R	0.807	0.82
334_A	337_Q	0.806	0.82
683_E	687_L	0.806	0.82
648_T	651_T	0.804	0.82
10_N	16_G	0.803	0.82
264_Q	268_Q	0.803	0.82
997_A	1020_M	0.802	0.82
308_H	315_E	0.800	0.82
169_R	937_V	0.800	0.82
222_T	226_Q	0.798	0.82
571_R	574_E	0.797	0.82
449_I	453_T	0.797	0.82
743_A	746_S	0.797	0.82
994_L	1017_V	0.796	0.81
202_K	206_Q	0.796	0.81
294_P	298_R	0.795	0.81
188_M	192_Q	0.792	0.81
174_E	903_T	0.791	0.81
168_E	171_E	0.791	0.81
495_A	498_A	0.790	0.81
803_T	811_Q	0.789	0.81
919_H	922_Y	0.788	0.81
492_T	502_A	0.787	0.81
747_L	754_F	0.786	0.81
910_L	969_D	0.785	0.81
262_R	266_L	0.785	0.81
809_Q	814_R	0.785	0.81
1009_K	1017_V	0.783	0.80
286_A	289_A	0.782	0.80
341_L	348_L	0.781	0.80
85_F	140_T	0.780	0.80
244_Q	247_N	0.780	0.80
938_D	959_V	0.779	0.80
991_S	1018_E	0.778	0.80
623_G	626_A	0.778	0.80
769_F	773_L	0.778	0.80
454_Q	458_Q	0.778	0.80
12_N	34_A	0.777	0.80
72_M	75_D	0.775	0.80
304_A	308_H	0.775	0.80
639_I	647_L	0.775	0.80
48_D	154_S	0.774	0.80
980_L	1009_K	0.774	0.80
574_E	578_T	0.773	0.80
479_D	484_C	0.773	0.80
618_R	622_Q	0.772	0.79
783_E	789_L	0.772	0.79
802_Q	814_R	0.772	0.79
255_L	258_E	0.772	0.79
436_V	439_Q	0.771	0.79
628_H	635_Y	0.771	0.79
703_Q	707_L	0.770	0.79
482_T	500_L	0.770	0.79
353_Q	357_R	0.770	0.79
497_R	501_Q	0.770	0.79
957_F	1017_V	0.768	0.79
667_L	671_Q	0.767	0.79
12_N	69_N	0.766	0.79
38_P	71_L	0.766	0.79
470_Y	474_T	0.766	0.79
689_N	693_Q	0.766	0.79
8_L	46_L	0.766	0.79
576_A	580_Q	0.764	0.79
418_H	422_R	0.763	0.79
863_Q	867_M	0.762	0.79
938_D	994_L	0.762	0.79
903_T	907_L	0.761	0.78
72_M	79_C	0.761	0.78
338_S	345_Q	0.761	0.78
396_L	406_L	0.760	0.78
67_S	71_L	0.759	0.78
269_A	276_A	0.759	0.78
633_I	637_Q	0.758	0.78
423_P	426_Q	0.757	0.78
793_R	800_V	0.756	0.78
874_T	878_E	0.756	0.78
174_E	183_G	0.755	0.78
537_N	541_K	0.754	0.78
867_M	870_I	0.754	0.78
566_E	570_L	0.753	0.78
488_A	499_Q	0.752	0.78
233_K	239_Q	0.751	0.78
364_E	367_G	0.751	0.78
156_G	960_S	0.750	0.77
488_A	496_Q	0.748	0.77
371_Q	375_Q	0.748	0.77
971_V	981_F	0.748	0.77
769_F	772_A	0.747	0.77
1024_I	1027_Q	0.747	0.77
11_L	45_T	0.746	0.77
842_N	846_Q	0.746	0.77
184_Q	188_M	0.746	0.77
563_D	577_L	0.745	0.77
311_Q	314_E	0.744	0.77
950_T	968_S	0.744	0.77
48_D	51_C	0.742	0.77
220_S	229_T	0.739	0.76
968_S	980_L	0.739	0.76
968_S	988_T	0.738	0.76
431_L	434_Q	0.738	0.76
833_A	837_Q	0.737	0.76
948_T	988_T	0.736	0.76
750_A	757_A	0.734	0.76
560_L	564_E	0.734	0.76
61_L	66_Q	0.734	0.76
957_F	964_A	0.732	0.76
558_K	562_R	0.731	0.76
665_S	669_T	0.730	0.76
232_E	240_Q	0.730	0.76
777_Q	781_Q	0.730	0.76
154_S	986_F	0.730	0.76
661_D	672_Q	0.729	0.75
453_T	457_T	0.729	0.75
244_Q	248_W	0.729	0.75
944_A	1018_E	0.727	0.75
303_S	311_Q	0.727	0.75
593_Q	597_D	0.727	0.75
854_K	858_D	0.726	0.75
95_F	117_A	0.726	0.75
499_Q	504_Q	0.725	0.75
535_L	538_E	0.725	0.75
498_A	501_Q	0.724	0.75
866_L	873_M	0.724	0.75
311_Q	326_L	0.724	0.75
402_I	405_T	0.723	0.75
12_N	1010_T	0.721	0.75
964_A	981_F	0.721	0.75
984_E	1014_I	0.720	0.75
638_Q	642_R	0.720	0.75
932_L	985_G	0.720	0.75
798_T	807_L	0.719	0.74
439_Q	442_L	0.719	0.74
791_N	794_R	0.718	0.74
934_V	941_Q	0.716	0.74
386_Q	394_Q	0.716	0.74
793_R	796_A	0.716	0.74
10_N	13_S	0.715	0.74
722_V	729_L	0.713	0.74
748_Q	752_A	0.713	0.74
435_I	455_E	0.713	0.74
450_Q	453_T	0.712	0.74
70_D	73_T	0.709	0.73
426_Q	430_A	0.709	0.73
38_P	1032_K	0.706	0.73
439_Q	446_Q	0.706	0.73
202_K	209_G	0.706	0.73
982_L	1000_A	0.706	0.73
680_R	684_L	0.705	0.73
691_I	695_T	0.705	0.73
10_N	36_T	0.704	0.73
159_A	170_A	0.704	0.73
956_S	993_T	0.704	0.73
980_L	1020_M	0.700	0.72
47_L	174_E	0.700	0.72
301_E	304_A	0.700	0.72
710_C	714_V	0.700	0.72
142_L	169_R	0.700	0.72
964_A	1017_V	0.698	0.72
968_S	981_F	0.698	0.72
742_L	745_Q	0.697	0.72
630_Q	634_Q	0.697	0.72
978_D	1010_T	0.696	0.72
303_S	317_N	0.696	0.72
1015_S	1028_I	0.693	0.72
349_N	353_Q	0.692	0.72
387_Q	390_T	0.692	0.72
932_L	937_V	0.692	0.72
1010_T	1024_I	0.692	0.72
563_D	567_A	0.691	0.72
498_A	502_A	0.691	0.72
744_A	751_Q	0.691	0.72
740_D	751_Q	0.690	0.71
839_L	842_N	0.690	0.71
170_A	897_K	0.689	0.71
735_T	739_Q	0.688	0.71
217_Q	223_A	0.688	0.71
330_I	334_A	0.687	0.71
318_T	330_I	0.687	0.71
12_N	71_L	0.687	0.71
158_F	1017_V	0.687	0.71
159_A	173_L	0.687	0.71
771_A	774_M	0.686	0.71
463_L	470_Y	0.686	0.71
68_Q	71_L	0.686	0.71
631_Q	635_Y	0.684	0.71
141_G	169_R	0.681	0.70
964_A	968_S	0.681	0.70
805_E	814_R	0.681	0.70
321_Q	336_K	0.680	0.70
608_H	611_Q	0.680	0.70
911_A	986_F	0.680	0.70
297_E	300_A	0.679	0.70
418_H	421_Q	0.679	0.70
997_A	1021_K	0.678	0.70
181_I	185_I	0.677	0.70
500_L	505_P	0.675	0.70
811_Q	815_P	0.675	0.70
964_A	993_T	0.675	0.70
971_V	977_I	0.673	0.70
170_A	179_T	0.673	0.70
12_N	174_E	0.673	0.70
1019_A	1023_R	0.672	0.69
421_Q	424_L	0.672	0.69
934_V	940_W	0.670	0.69
47_L	154_S	0.670	0.69
489_R	497_R	0.669	0.69
540_K	544_E	0.669	0.69
13_S	60_R	0.669	0.69
934_V	938_D	0.669	0.69
383_R	390_T	0.669	0.69
948_T	958_L	0.669	0.69
378_D	382_L	0.668	0.69
47_L	52_L	0.667	0.69
494_E	497_R	0.667	0.69
12_N	70_D	0.667	0.69
908_V	912_N	0.666	0.69
48_D	989_L	0.665	0.69
543_G	547_A	0.665	0.69
452_V	456_Q	0.664	0.68
670_R	673_E	0.663	0.68
44_T	59_P	0.663	0.68
307_A	317_N	0.662	0.68
961_L	997_A	0.662	0.68
986_F	997_A	0.660	0.68
987_G	993_T	0.660	0.68
550_R	553_L	0.660	0.68
684_L	688_Q	0.658	0.68
16_G	73_T	0.657	0.68
887_I	1037_G	0.657	0.68
957_F	1021_K	0.657	0.68
71_L	174_E	0.656	0.68
556_I	560_L	0.656	0.68
12_N	159_A	0.656	0.68
5_S	84_E	0.656	0.68
202_K	228_L	0.655	0.67
988_T	1020_M	0.654	0.67
256_Q	263_Q	0.654	0.67
156_G	169_R	0.653	0.67
584_V	591_T	0.653	0.67
425_R	428_L	0.652	0.67
6_L	83_V	0.652	0.67
48_D	1014_I	0.651	0.67
154_S	159_A	0.651	0.67
664_E	667_L	0.651	0.67
855_Q	859_N	0.650	0.67
951_L	963_L	0.650	0.67
371_Q	374_Q	0.650	0.67
590_I	593_Q	0.650	0.67
569_S	572_Q	0.650	0.67
839_L	845_S	0.649	0.67
955_E	993_T	0.648	0.67
12_N	79_C	0.648	0.67
490_I	496_Q	0.647	0.67
218_V	221_L	0.646	0.66
986_F	998_L	0.646	0.66
52_L	96_W	0.645	0.66
1001_L	1009_K	0.645	0.66
729_L	736_L	0.645	0.66
177_T	903_T	0.645	0.66
296_W	315_E	0.645	0.66
491_K	500_L	0.644	0.66
809_Q	821_L	0.644	0.66
998_L	1019_A	0.644	0.66
724_E	728_A	0.644	0.66
653_Y	656_T	0.643	0.66
1012_G	1017_V	0.643	0.66
927_K	930_E	0.643	0.66
10_N	79_C	0.642	0.66
382_L	392_A	0.642	0.66
583_A	586_A	0.642	0.66
461_A	467_R	0.641	0.66
303_S	315_E	0.641	0.66
778_T	782_L	0.640	0.66
740_D	747_L	0.640	0.66
566_E	569_S	0.638	0.65
158_F	964_A	0.638	0.65
393_E	400_A	0.638	0.65
308_H	312_Q	0.637	0.65
749_K	753_Q	0.637	0.65
738_Q	741_V	0.636	0.65
433_G	437_P	0.636	0.65
191_E	204_Q	0.636	0.65
217_Q	229_T	0.635	0.65
34_A	1022_E	0.635	0.65
786_K	796_A	0.635	0.65
801_T	805_E	0.634	0.65
628_H	631_Q	0.633	0.65
463_L	467_R	0.633	0.65
172_L	918_L	0.632	0.65
12_N	982_L	0.632	0.65
977_I	985_G	0.632	0.65
162_L	169_R	0.632	0.65
802_Q	805_E	0.631	0.65
960_S	989_L	0.631	0.65
252_Q	259_A	0.631	0.65
52_L	81_A	0.631	0.65
146_R	179_T	0.631	0.65
177_T	959_V	0.630	0.64
368_W	372_F	0.629	0.64
431_L	435_I	0.628	0.64
155_Q	984_E	0.628	0.64
808_A	812_Q	0.628	0.64
357_R	361_W	0.628	0.64
639_I	642_R	0.628	0.64
11_L	81_A	0.628	0.64
938_D	955_E	0.626	0.64
140_T	147_F	0.626	0.64
172_L	991_S	0.626	0.64
434_Q	437_P	0.626	0.64
980_L	997_A	0.625	0.64
955_E	1027_Q	0.624	0.64
170_A	980_L	0.624	0.64
594_P	598_I	0.624	0.64
430_A	433_G	0.624	0.64
980_L	1011_I	0.623	0.64
584_V	588_L	0.623	0.64
12_N	73_T	0.623	0.64
957_F	980_L	0.623	0.64
12_N	922_Y	0.622	0.63
632_I	639_I	0.622	0.63
959_V	988_T	0.622	0.63
932_L	986_F	0.621	0.63
174_E	971_V	0.620	0.63
393_E	396_L	0.620	0.63
376_T	379_R	0.620	0.63
551_G	555_A	0.620	0.63
159_A	988_T	0.619	0.63
639_I	646_L	0.619	0.63
807_L	813_H	0.618	0.63
68_Q	157_Q	0.617	0.63
589_N	593_Q	0.617	0.63
669_T	672_Q	0.617	0.63
36_T	993_T	0.617	0.63
781_Q	784_Q	0.617	0.63
841_E	845_S	0.615	0.63
147_F	964_A	0.615	0.63
146_R	908_V	0.614	0.62
499_Q	502_A	0.614	0.62
475_Q	479_D	0.614	0.62
991_S	1019_A	0.613	0.62
958_L	989_L	0.612	0.62
845_S	848_E	0.612	0.62
129_V	169_R	0.611	0.62
437_P	441_R	0.611	0.62
494_E	498_A	0.611	0.62
306_L	310_R	0.611	0.62
493_L	499_Q	0.611	0.62
50_I	981_F	0.610	0.62
170_A	959_V	0.609	0.62
787_Q	811_Q	0.609	0.62
306_L	309_I	0.608	0.62
164_A	1004_L	0.608	0.62
490_I	500_L	0.608	0.62
162_L	956_S	0.606	0.61
52_L	960_S	0.606	0.61
744_A	747_L	0.606	0.61
800_V	814_R	0.605	0.61
588_L	592_L	0.605	0.61
41_A	152_L	0.605	0.61
157_Q	175_E	0.604	0.61
359_R	363_N	0.602	0.61
219_Q	226_Q	0.602	0.61
489_R	495_A	0.602	0.61
466_M	475_Q	0.602	0.61
137_A	143_D	0.601	0.61
143_D	146_R	0.601	0.61
961_L	998_L	0.601	0.61
733_Q	737_Q	0.601	0.61
298_R	302_H	0.599	0.61
84_E	91_A	0.599	0.61
158_F	1012_G	0.599	0.61
497_R	504_Q	0.599	0.61
382_L	401_A	0.599	0.61
493_L	501_Q	0.598	0.60
142_L	147_F	0.598	0.60
722_V	726_C	0.597	0.60
225_L	232_E	0.597	0.60
399_L	402_I	0.596	0.60
320_L	327_R	0.596	0.60
994_L	1019_A	0.596	0.60
483_I	486_Q	0.595	0.60
206_Q	209_G	0.595	0.60
986_F	1021_K	0.595	0.60
297_E	304_A	0.594	0.60
596_D	600_P	0.594	0.60
51_C	980_L	0.594	0.60
393_E	402_I	0.594	0.60
142_L	153_L	0.593	0.60
548_T	552_Q	0.592	0.60
293_R	304_A	0.591	0.60
391_H	402_I	0.591	0.60
350_T	353_Q	0.590	0.59
73_T	79_C	0.590	0.59
293_R	300_A	0.590	0.59
714_V	720_R	0.590	0.59
937_V	940_W	0.589	0.59
14_L	177_T	0.589	0.59
414_A	417_Q	0.588	0.59
3_I	964_A	0.588	0.59
39_T	42_G	0.588	0.59
147_F	980_L	0.588	0.59
56_H	73_T	0.587	0.59
1017_V	1021_K	0.587	0.59
393_E	397_N	0.586	0.59
203_L	866_L	0.586	0.59
829_Q	833_A	0.585	0.59
918_L	966_A	0.585	0.59
480_V	483_I	0.584	0.59
173_L	908_V	0.584	0.59
40_G	953_G	0.583	0.59
152_L	179_T	0.583	0.59
642_R	650_L	0.582	0.58
125_L	132_K	0.582	0.58
868_Q	871_A	0.582	0.58
142_L	977_I	0.582	0.58
52_L	59_P	0.582	0.58
45_T	52_L	0.581	0.58
147_F	156_G	0.581	0.58
718_N	722_V	0.581	0.58
370_A	374_Q	0.581	0.58
1025_P	1028_I	0.581	0.58
11_L	161_F	0.580	0.58
495_A	500_L	0.580	0.58
718_N	725_Q	0.580	0.58
171_E	176_L	0.580	0.58
233_K	237_T	0.580	0.58
915_L	938_D	0.579	0.58
487_E	490_I	0.579	0.58
304_A	311_Q	0.579	0.58
70_D	116_L	0.579	0.58
155_Q	166_P	0.578	0.58
39_T	146_R	0.578	0.58
471_K	475_Q	0.578	0.58
435_I	438_Q	0.578	0.58
852_Q	856_D	0.578	0.58
191_E	195_S	0.577	0.58
985_G	997_A	0.576	0.58
382_L	386_Q	0.575	0.57
457_T	460_N	0.574	0.57
36_T	980_L	0.572	0.57
459_R	463_L	0.572	0.57
955_E	1014_I	0.572	0.57
477_L	480_V	0.572	0.57
45_T	55_Y	0.571	0.57
291_N	295_H	0.571	0.57
176_L	904_L	0.570	0.57
631_Q	646_L	0.570	0.57
142_L	904_L	0.570	0.57
971_V	1009_K	0.570	0.57
164_A	980_L	0.570	0.57
576_A	579_Q	0.569	0.57
1004_L	1016_H	0.569	0.57
40_G	155_Q	0.568	0.57
586_A	590_I	0.568	0.57
251_R	255_L	0.568	0.57
301_E	306_L	0.568	0.57
50_I	54_L	0.567	0.56
828_I	832_L	0.566	0.56
174_E	958_L	0.566	0.56
352_L	356_D	0.566	0.56
743_A	750_A	0.566	0.56
994_L	998_L	0.566	0.56
222_T	227_V	0.566	0.56
157_Q	169_R	0.565	0.56
382_L	385_W	0.565	0.56
539_V	549_L	0.564	0.56
643_Q	649_T	0.564	0.56
334_A	341_L	0.563	0.56
155_Q	1014_I	0.563	0.56
380_E	387_Q	0.563	0.56
915_L	968_S	0.562	0.56
968_S	1009_K	0.562	0.56
729_L	733_Q	0.562	0.56
436_V	440_K	0.562	0.56
478_A	482_T	0.562	0.56
980_L	985_G	0.561	0.56
1021_K	1027_Q	0.561	0.56
160_A	172_L	0.561	0.56
256_Q	260_S	0.561	0.56
586_A	589_N	0.561	0.56
978_D	1011_I	0.560	0.55
14_L	52_L	0.558	0.55
147_F	180_E	0.558	0.55
794_R	802_Q	0.558	0.55
448_A	469_R	0.558	0.55
357_R	360_Q	0.557	0.55
472_E	475_Q	0.556	0.55
932_L	1017_V	0.555	0.55
223_A	228_L	0.555	0.55
723_H	727_L	0.555	0.55
321_Q	324_M	0.555	0.55
39_T	1010_T	0.555	0.55
142_L	174_E	0.555	0.55
621_L	646_L	0.555	0.55
934_V	939_T	0.555	0.55
948_T	993_T	0.554	0.55
50_I	55_Y	0.554	0.55
396_L	400_A	0.554	0.55
938_D	986_F	0.554	0.55
39_T	43_K	0.553	0.55
908_V	964_A	0.553	0.55
918_L	962_A	0.553	0.55
948_T	978_D	0.553	0.55
50_I	83_V	0.552	0.54
589_N	594_P	0.552	0.54
12_N	979_S	0.552	0.54
943_D	955_E	0.552	0.54
55_Y	911_A	0.551	0.54
580_Q	584_V	0.551	0.54
964_A	1012_G	0.551	0.54
45_T	70_D	0.551	0.54
218_V	232_E	0.550	0.54
38_P	993_T	0.550	0.54
207_A	918_L	0.550	0.54
931_A	935_E	0.549	0.54
932_L	935_E	0.548	0.54
903_T	959_V	0.547	0.54
538_E	545_E	0.547	0.54
1011_I	1017_V	0.547	0.54
193_H	877_V	0.547	0.54
542_L	548_T	0.547	0.54
460_N	475_Q	0.547	0.54
31_G	100_R	0.546	0.54
159_A	956_S	0.546	0.54
48_D	146_R	0.546	0.54
933_E	937_V	0.544	0.53
31_G	60_R	0.544	0.53
34_A	922_Y	0.544	0.53
41_A	980_L	0.544	0.53
543_G	550_R	0.544	0.53
793_R	797_Q	0.544	0.53
964_A	988_T	0.542	0.53
33_F	911_A	0.542	0.53
154_S	173_L	0.542	0.53
10_N	177_T	0.542	0.53
994_L	1000_A	0.541	0.53
672_Q	675_Q	0.541	0.53
589_N	599_Q	0.541	0.53
52_L	170_A	0.540	0.53
380_E	383_R	0.540	0.53
293_R	303_S	0.540	0.53
911_A	922_Y	0.540	0.53
866_L	870_I	0.538	0.53
983_D	990_D	0.538	0.53
980_L	1027_Q	0.537	0.52
852_Q	862_Q	0.536	0.52
10_N	186_S	0.536	0.52
10_N	1028_I	0.536	0.52
14_L	96_W	0.536	0.52
831_E	835_T	0.536	0.52
582_Q	585_T	0.535	0.52
487_E	491_K	0.535	0.52
959_V	969_D	0.535	0.52
163_N	169_R	0.534	0.52
239_Q	246_L	0.534	0.52
638_Q	641_Q	0.534	0.52
552_Q	555_A	0.533	0.52
910_L	913_Q	0.533	0.52
256_Q	259_A	0.533	0.52
721_Q	724_E	0.532	0.52
810_H	815_P	0.532	0.52
378_D	387_Q	0.532	0.52
51_C	56_H	0.532	0.52
40_G	43_K	0.532	0.52
331_R	334_A	0.532	0.52
883_L	886_L	0.532	0.52
395_K	401_A	0.531	0.52
300_A	304_A	0.531	0.52
948_T	964_A	0.531	0.52
78_E	97_S	0.531	0.52
153_L	915_L	0.530	0.52
175_E	185_I	0.529	0.51
319_R	344_Q	0.528	0.51
964_A	971_V	0.528	0.51
981_F	1014_I	0.527	0.51
490_I	493_L	0.527	0.51
116_L	971_V	0.526	0.51
683_E	690_R	0.526	0.51
465_E	468_Q	0.525	0.51
554_D	558_K	0.525	0.51
154_S	948_T	0.525	0.51
960_S	984_E	0.524	0.51
176_L	950_T	0.524	0.51
579_Q	583_A	0.524	0.51
965_L	1029_K	0.524	0.51
475_Q	483_I	0.523	0.51
783_E	796_A	0.523	0.51
664_E	669_T	0.522	0.50
991_S	1032_K	0.522	0.50
191_E	194_K	0.521	0.50
161_F	934_V	0.521	0.50
807_L	811_Q	0.521	0.50
911_A	964_A	0.520	0.50
51_C	1015_S	0.519	0.50
964_A	1009_K	0.518	0.50
785_L	788_N	0.518	0.50
12_N	72_M	0.517	0.50
573_D	577_L	0.517	0.50
397_N	402_I	0.517	0.50
381_H	385_W	0.517	0.50
153_L	1002_D	0.516	0.50
45_T	69_N	0.516	0.50
488_A	498_A	0.516	0.50
44_T	49_A	0.516	0.50
11_L	943_D	0.515	0.50
293_R	306_L	0.515	0.50
154_S	170_A	0.515	0.50
212_L	223_A	0.514	0.49
243_Q	246_L	0.514	0.49
946_R	985_G	0.513	0.49
21_D	162_L	0.513	0.49
932_L	997_A	0.513	0.49
322_S	330_I	0.512	0.49
804_A	809_Q	0.512	0.49
694_L	708_P	0.512	0.49
994_L	1005_N	0.512	0.49
997_A	1011_I	0.511	0.49
389_L	397_N	0.511	0.49
73_T	907_L	0.511	0.49
482_T	486_Q	0.510	0.49
635_Y	649_T	0.510	0.49
47_L	59_P	0.510	0.49
707_L	710_C	0.510	0.49
935_E	959_V	0.510	0.49
726_C	737_Q	0.509	0.49
958_L	996_T	0.509	0.49
59_P	160_A	0.509	0.49
157_Q	163_N	0.508	0.49
978_D	986_F	0.508	0.49
47_L	179_T	0.508	0.49
858_D	861_Q	0.508	0.49
964_A	1004_L	0.508	0.49
44_T	60_R	0.507	0.48
493_L	498_A	0.507	0.48
98_Q	146_R	0.506	0.48
988_T	1021_K	0.506	0.48
911_A	1009_K	0.506	0.48
41_A	988_T	0.506	0.48
1033_I	1040_K	0.506	0.48
140_T	154_S	0.506	0.48
22_F	934_V	0.506	0.48
703_Q	708_P	0.505	0.48
946_R	957_F	0.505	0.48
186_S	189_V	0.505	0.48
908_V	1004_L	0.504	0.48
231_E	234_Q	0.504	0.48
541_K	544_E	0.504	0.48
11_L	94_A	0.503	0.48
681_Q	684_L	0.503	0.48
575_Q	579_Q	0.503	0.48
96_W	907_L	0.502	0.48
161_F	173_L	0.502	0.48
1000_A	1004_L	0.502	0.48
494_E	502_A	0.502	0.48
994_L	1011_I	0.502	0.48
152_L	157_Q	0.500	0.48

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4ux3A	1	0.4027	100	0.695	Contact Map
3auyA	2	0.3492	100	0.719	Contact Map
3zgxA	2	0.3168	100	0.721	Contact Map
4ad8A	1	0.3931	100	0.743	Contact Map
3qf7A	2	0.3368	100	0.753	Contact Map
1w1wA	2	0.3053	100	0.759	Contact Map
3qksA	1	0.187	100	0.799	Contact Map
3qktA	2	0.3206	100	0.801	Contact Map
4i99A	2	0.2929	100	0.802	Contact Map
4abyA	1	0.3225	100	0.808	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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