FECA - ECOLI - GREMLIN Contacts

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FECA - Fe(3+) dicitrate transport protein FecA

UniProt:	P13036	Sequences: MTPLRVFRKTTPLVNTIRLSLLPLAGLSFSAFAAQVNIAPGSLDKALNQYAAHSGFTLSVDASLTRGKQSNGLHGDYDVESGLQQLLDGSGLQVKPLGNNSWTLEPAPAPKEDALTVVGDWLGDARENDVFEHAGARDVIRREDFAKTGATTMREVLNRIPGVSAPENNGTGSHDLAMNFGIRGLNPRLASRSTVLMDGIPVPFAPYGQPQLSLAPVSLGNMDAIDVVRGGGAVRYGPQSVGGVVNFVTRAIPQDFGIEAGVEGQLSPTSSQNNPKETHNLMVGGTADNGFGTALLYSGTRGSDWREHSATRIDDLMLKSKYAPDEVHTFNSLLQYYDGEADMPGGLSRADYDADRWQSTRPYDRFWGRRKLASLGYQFQPDSQHKFNIQGFYTQTLRSGYLEQGKRITLSPRNYWVRGIEPRYSQIFMIGPSAHEVGVGYRYLNESTHEMRYYTATSSGQLPSGSSPYDRDTRSGTEAHAWYLDDKIDIGNWTITPGMRFEHIESYQNNAITGTHEEVSYNAPLPALNVLYHLTDSWNLYANTEGSFGTVQYSQIGKAVQSGNVEPEKARTWELGTRYDDGALTAEMGLFLINFNNQYDSNQTNDTVTARGKTRHTGLETQARYDLGTLTPTLDNVSIYASYAYVNAEIREKGDTYGNLVPFSPKHKGTLGVDYKPGNWTFNLNSDFQSSQFADNANTVKESADGSTGRIPGFMLWGARVAYDFGPQMADLNLAFGVKNIFDQDYFIRSYDDNNKGIYAGQPRTLYMQGSLKF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10286
Length:	774 (610)
Sequences:	49905 (41044)
Seq/√Len:	1661.8

ECOLI - FECA FHUA YNCD FHUE FIU BTUB CIRA FEPA YDDB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
643_Y	667_H	3.944	1.00
686_S	715_M	3.798	1.00
291_F	322_Y	3.609	1.00
501_F	522_N	3.609	1.00
499_M	524_P	3.551	1.00
592_L	617_T	3.449	1.00
328_H	379_F	3.397	1.00
538_W	577_T	3.335	1.00
544_T	571_R	3.308	1.00
735_A	769_Q	3.240	1.00
546_G	571_R	3.220	1.00
681_T	722_A	3.160	1.00
501_F	524_P	3.007	1.00
299_G	314_D	2.984	1.00
640_Y	672_G	2.843	1.00
435_H	486_D	2.813	1.00
331_N	376_G	2.794	1.00
615_R	651_R	2.778	1.00
297_Y	314_D	2.658	1.00
538_W	579_Y	2.534	1.00
336_Y	371_K	2.508	1.00
328_H	377_Y	2.504	1.00
592_L	615_R	2.480	1.00
329_T	378_Q	2.456	1.00
493_W	532_Y	2.449	1.00
637_V	673_V	2.428	1.00
440_G	483_Y	2.427	1.00
717_W	742_F	2.380	1.00
492_N	532_Y	2.354	1.00
334_L	371_K	2.348	1.00
224_A	248_V	2.333	1.00
327_V	379_F	2.330	1.00
584_L	625_Y	2.316	1.00
142_R	146_A	2.308	1.00
645_Y	667_H	2.282	1.00
579_Y	586_A	2.277	1.00
738_V	741_I	2.261	1.00
686_S	717_W	2.184	1.00
737_G	767_Y	2.170	1.00
454_Y	459_S	2.138	1.00
291_F	320_S	2.137	1.00
222_M	247_F	2.133	1.00
688_F	715_M	2.110	1.00
285_G	293_T	2.094	1.00
389_I	422_P	2.077	1.00
534_L	540_L	2.040	1.00
141_R	144_D	2.032	1.00
638_S	674_D	2.031	1.00
325_D	328_H	2.025	1.00
338_D	369_R	2.017	1.00
585_T	624_R	2.015	1.00
292_G	321_K	2.011	1.00
445_N	478_E	2.005	1.00
683_N	720_R	2.003	1.00
733_N	771_S	1.999	1.00
722_A	733_N	1.996	1.00
684_L	717_W	1.983	1.00
546_G	569_K	1.964	1.00
389_I	420_I	1.960	1.00
441_Y	480_H	1.946	1.00
421_E	442_R	1.934	1.00
531_L	539_N	1.923	1.00
587_E	622_Q	1.893	1.00
691_S	710_R	1.885	1.00
391_G	418_R	1.872	1.00
627_L	634_L	1.854	1.00
724_D	733_N	1.846	1.00
330_F	377_Y	1.844	1.00
387_F	422_P	1.835	1.00
384_Q	426_Q	1.831	1.00
393_Y	418_R	1.823	1.00
732_L	772_L	1.812	1.00
295_L	318_L	1.803	1.00
334_L	373_A	1.794	1.00
503_H	522_N	1.782	1.00
534_L	538_W	1.776	1.00
669_G	688_F	1.772	1.00
544_T	573_W	1.771	1.00
494_T	533_H	1.758	1.00
197_M	202_V	1.741	1.00
321_K	329_T	1.733	1.00
443_Y	480_H	1.730	1.00
624_R	640_Y	1.727	1.00
493_W	530_V	1.722	1.00
152_T	155_E	1.722	1.00
378_Q	386_K	1.719	1.00
445_N	476_G	1.704	1.00
385_H	426_Q	1.696	1.00
298_S	315_D	1.692	1.00
601_S	608_V	1.685	1.00
636_N	675_Y	1.679	1.00
594_N	613_K	1.669	1.00
586_A	623_A	1.664	1.00
571_R	596_N	1.660	1.00
594_N	615_R	1.659	1.00
427_I	436_E	1.654	1.00
598_Q	614_T	1.654	1.00
139_V	226_D	1.652	1.00
590_L	617_T	1.646	1.00
736_F	766_L	1.638	1.00
254_Q	292_G	1.630	1.00
639_I	671_L	1.626	1.00
680_W	723_Y	1.617	1.00
323_A	329_T	1.613	1.00
732_L	770_G	1.608	1.00
388_N	423_R	1.607	1.00
591_F	646_V	1.604	1.00
293_T	320_S	1.604	1.00
526_P	546_G	1.602	1.00
301_R	312_R	1.602	1.00
378_Q	388_N	1.587	1.00
321_K	331_N	1.585	1.00
435_H	488_I	1.572	1.00
489_D	494_T	1.568	1.00
685_N	718_G	1.566	1.00
572_T	593_I	1.566	1.00
533_H	537_S	1.565	1.00
332_S	373_A	1.556	1.00
738_V	766_L	1.550	1.00
293_T	297_Y	1.542	1.00
223_D	250_R	1.540	1.00
639_I	673_V	1.535	1.00
535_T	538_W	1.535	1.00
160_I	227_V	1.534	1.00
429_M	434_A	1.534	1.00
588_M	621_T	1.534	1.00
688_F	713_G	1.528	1.00
583_A	625_Y	1.524	1.00
725_F	734_L	1.521	1.00
198_D	319_K	1.506	1.00
391_G	420_I	1.503	1.00
290_G	322_Y	1.499	1.00
226_D	246_N	1.499	1.00
627_L	639_I	1.488	1.00
617_T	647_N	1.480	1.00
637_V	675_Y	1.479	1.00
746_Y	761_G	1.475	1.00
578_R	587_E	1.467	1.00
613_K	652_E	1.466	1.00
129_D	132_E	1.456	1.00
719_A	741_I	1.449	1.00
526_P	530_V	1.436	1.00
182_I	243_G	1.436	1.00
523_A	569_K	1.436	1.00
580_D	585_T	1.435	1.00
197_M	249_T	1.432	1.00
143_E	147_K	1.427	1.00
384_Q	428_F	1.424	1.00
540_L	577_T	1.423	1.00
726_G	731_D	1.422	1.00
392_F	419_G	1.415	1.00
541_Y	576_G	1.409	1.00
738_V	764_R	1.409	1.00
566_E	597_N	1.407	1.00
494_T	531_L	1.407	1.00
591_F	618_G	1.406	1.00
642_S	670_T	1.405	1.00
635_D	675_Y	1.403	1.00
183_R	620_E	1.403	1.00
385_H	424_Y	1.395	1.00
387_F	424_Y	1.394	1.00
542_A	573_W	1.394	1.00
433_S	488_I	1.388	1.00
380_Q	386_K	1.387	1.00
436_E	487_K	1.381	1.00
681_T	724_D	1.374	1.00
142_R	250_R	1.372	1.00
223_D	251_A	1.367	1.00
732_L	736_F	1.363	1.00
541_Y	578_R	1.362	1.00
330_F	375_L	1.361	1.00
144_D	147_K	1.359	1.00
679_N	723_Y	1.359	1.00
481_A	502_E	1.350	1.00
734_L	770_G	1.349	1.00
386_K	425_S	1.344	1.00
569_K	597_N	1.344	1.00
218_S	221_N	1.344	1.00
574_E	589_G	1.342	1.00
101_S	104_L	1.341	1.00
674_D	683_N	1.340	1.00
292_G	323_A	1.336	1.00
278_T	281_L	1.327	1.00
329_T	380_Q	1.326	1.00
198_D	249_T	1.326	1.00
672_G	685_N	1.323	1.00
588_M	619_L	1.322	1.00
295_L	316_L	1.318	1.00
481_A	500_R	1.316	1.00
162_G	644_A	1.316	1.00
644_A	668_K	1.313	1.00
395_Q	416_W	1.309	1.00
626_D	638_S	1.304	1.00
495_I	530_V	1.301	1.00
549_G	568_E	1.300	1.00
143_E	146_A	1.300	1.00
584_L	623_A	1.299	1.00
681_T	733_N	1.299	1.00
436_E	489_D	1.298	1.00
667_H	690_S	1.285	1.00
251_A	321_K	1.280	1.00
529_N	543_N	1.278	1.00
376_G	388_N	1.278	1.00
327_V	380_Q	1.272	1.00
768_M	772_L	1.272	1.00
148_T	159_R	1.269	1.00
434_A	489_D	1.261	1.00
282_M	294_A	1.259	1.00
336_Y	369_R	1.259	1.00
258_I	283_V	1.259	1.00
382_D	385_H	1.258	1.00
680_W	721_V	1.256	1.00
541_Y	589_G	1.256	1.00
720_R	735_A	1.254	1.00
682_F	721_V	1.253	1.00
619_L	645_Y	1.253	1.00
297_Y	316_L	1.252	1.00
265_Q	268_P	1.251	1.00
497_P	528_L	1.247	1.00
485_D	496_T	1.247	1.00
600_D	611_R	1.244	1.00
638_S	676_K	1.242	1.00
725_F	732_L	1.234	1.00
381_P	387_F	1.234	1.00
198_D	333_L	1.229	1.00
538_W	542_A	1.224	1.00
687_D	718_G	1.221	1.00
155_E	158_N	1.221	1.00
423_R	483_Y	1.219	1.00
333_L	374_S	1.218	1.00
641_A	671_L	1.218	1.00
575_L	590_L	1.213	1.00
441_Y	482_W	1.212	1.00
251_A	319_K	1.211	1.00
502_E	525_L	1.206	1.00
722_A	735_A	1.203	1.00
442_R	481_A	1.196	1.00
324_P	330_F	1.192	1.00
332_S	375_L	1.191	1.00
718_G	739_K	1.188	1.00
739_K	765_T	1.187	1.00
636_N	676_K	1.185	1.00
573_W	592_L	1.179	1.00
293_T	318_L	1.177	1.00
430_I	435_H	1.170	1.00
331_N	378_Q	1.167	1.00
294_A	319_K	1.166	1.00
487_K	496_T	1.164	1.00
624_R	638_S	1.161	1.00
381_P	424_Y	1.157	1.00
338_D	367_W	1.155	1.00
492_N	534_L	1.154	1.00
503_H	520_S	1.153	1.00
590_L	619_L	1.153	1.00
138_D	229_R	1.153	1.00
573_W	594_N	1.153	1.00
395_Q	414_N	1.145	1.00
183_R	574_E	1.139	1.00
733_N	773_K	1.138	1.00
634_L	678_G	1.138	1.00
161_P	622_Q	1.136	1.00
717_W	744_Q	1.132	1.00
689_Q	692_Q	1.131	1.00
316_L	336_Y	1.127	1.00
530_V	534_L	1.124	1.00
103_T	106_P	1.121	1.00
736_F	768_M	1.120	1.00
163_V	182_I	1.112	1.00
684_L	719_A	1.109	1.00
586_A	621_T	1.108	1.00
104_L	107_A	1.106	1.00
376_G	390_Q	1.105	1.00
443_Y	478_E	1.090	1.00
533_H	536_D	1.088	1.00
653_K	656_T	1.085	1.00
299_G	312_R	1.084	1.00
104_L	108_P	1.083	1.00
196_L	201_P	1.081	1.00
393_Y	416_W	1.079	1.00
390_Q	421_E	1.078	1.00
613_K	651_R	1.076	1.00
480_H	503_H	1.074	1.00
200_I	392_F	1.073	1.00
717_W	741_I	1.072	1.00
596_N	613_K	1.067	1.00
616_H	648_A	1.060	1.00
570_A	593_I	1.058	1.00
111_K	114_A	1.057	1.00
645_Y	666_K	1.056	1.00
594_N	651_R	1.056	1.00
437_V	486_D	1.056	1.00
542_A	575_L	1.055	1.00
335_Q	372_L	1.052	1.00
669_G	690_S	1.052	1.00
330_F	334_L	1.050	1.00
229_R	620_E	1.044	1.00
388_N	425_S	1.043	1.00
676_K	681_T	1.041	1.00
586_A	590_L	1.041	1.00
265_Q	271_S	1.039	1.00
223_D	248_V	1.035	1.00
112_E	115_L	1.034	1.00
164_S	668_K	1.033	1.00
674_D	681_T	1.026	1.00
142_R	223_D	1.022	1.00
496_T	529_N	1.019	1.00
726_G	730_A	1.019	1.00
226_D	248_V	1.016	1.00
218_S	298_S	1.013	1.00
271_S	275_P	1.012	1.00
386_K	427_I	1.011	1.00
267_S	280_N	1.011	1.00
673_V	684_L	1.010	1.00
576_G	589_G	1.007	1.00
627_L	673_V	1.006	1.00
540_L	575_L	1.005	1.00
267_S	771_S	1.004	1.00
482_W	501_F	1.004	1.00
495_I	528_L	1.003	1.00
487_K	494_T	1.002	1.00
720_R	737_G	1.002	1.00
296_L	317_M	0.997	1.00
325_D	379_F	0.993	1.00
160_I	163_V	0.992	1.00
161_P	642_S	0.988	1.00
533_H	539_N	0.987	1.00
537_S	579_Y	0.985	1.00
241_V	570_A	0.982	1.00
490_I	495_I	0.980	1.00
734_L	768_M	0.977	1.00
504_I	550_T	0.973	1.00
270_S	276_K	0.973	1.00
726_G	732_L	0.972	1.00
323_A	326_E	0.971	1.00
716_L	746_Y	0.971	1.00
721_V	738_V	0.969	1.00
227_V	245_V	0.967	1.00
534_L	577_T	0.967	1.00
460_G	463_P	0.966	1.00
347_L	352_Y	0.965	1.00
687_D	716_L	0.964	1.00
139_V	224_A	0.961	1.00
547_S	570_A	0.960	1.00
573_W	577_T	0.958	1.00
434_A	488_I	0.951	1.00
577_T	588_M	0.948	1.00
735_A	771_S	0.948	1.00
689_Q	714_F	0.946	1.00
447_S	474_R	0.945	1.00
693_F	710_R	0.940	1.00
132_E	533_H	0.939	1.00
724_D	773_K	0.939	1.00
370_R	394_T	0.934	1.00
221_N	317_M	0.933	1.00
194_T	201_P	0.931	1.00
498_G	527_A	0.930	1.00
221_N	296_L	0.930	1.00
553_Y	556_I	0.930	1.00
426_Q	437_V	0.930	1.00
583_A	626_D	0.927	1.00
281_L	285_G	0.926	1.00
570_A	595_F	0.925	1.00
105_E	108_P	0.924	1.00
591_F	644_A	0.923	1.00
110_P	115_L	0.922	1.00
641_A	669_G	0.922	1.00
310_A	342_D	0.922	1.00
588_M	592_L	0.920	1.00
477_T	506_S	0.918	1.00
180_F	245_V	0.917	1.00
583_A	627_L	0.916	1.00
324_P	377_Y	0.916	1.00
195_V	245_V	0.911	1.00
196_L	246_N	0.909	1.00
387_F	391_G	0.907	1.00
266_L	270_S	0.907	1.00
332_S	336_Y	0.906	1.00
710_R	748_I	0.906	1.00
147_K	674_D	0.905	1.00
739_K	767_Y	0.905	1.00
200_I	390_Q	0.904	1.00
526_P	544_T	0.904	1.00
290_G	324_P	0.903	1.00
525_L	548_F	0.901	1.00
435_H	440_G	0.899	1.00
625_Y	639_I	0.898	1.00
591_F	620_E	0.897	1.00
348_S	351_D	0.897	1.00
734_L	738_V	0.896	1.00
251_A	331_N	0.893	1.00
97_L	105_E	0.892	1.00
267_S	271_S	0.889	1.00
731_D	772_L	0.888	1.00
319_K	331_N	0.887	1.00
523_A	548_F	0.886	1.00
290_G	323_A	0.886	1.00
658_G	661_V	0.886	1.00
324_P	328_H	0.882	1.00
221_N	294_A	0.882	1.00
142_R	145_F	0.880	1.00
716_L	761_G	0.880	1.00
254_Q	289_N	0.880	1.00
691_S	713_G	0.877	1.00
428_F	437_V	0.877	1.00
180_F	195_V	0.876	1.00
145_F	156_V	0.871	1.00
134_A	529_N	0.870	1.00
380_Q	383_S	0.868	1.00
196_L	244_V	0.868	1.00
646_V	664_S	0.868	1.00
153_M	247_F	0.867	1.00
741_I	764_R	0.866	1.00
138_D	622_Q	0.865	1.00
499_M	526_P	0.865	1.00
144_D	159_R	0.864	1.00
96_P	99_N	0.861	1.00
568_E	595_F	0.857	1.00
427_I	434_A	0.857	1.00
340_E	367_W	0.856	1.00
422_P	426_Q	0.854	1.00
643_Y	669_G	0.853	1.00
571_R	594_N	0.853	1.00
488_I	497_P	0.853	1.00
265_Q	773_K	0.850	1.00
274_N	303_S	0.846	1.00
102_W	105_E	0.843	1.00
134_A	531_L	0.842	1.00
268_P	278_T	0.840	1.00
601_S	606_D	0.840	1.00
528_L	544_T	0.839	1.00
482_W	503_H	0.837	1.00
743_D	763_P	0.836	1.00
482_W	486_D	0.835	1.00
634_L	637_V	0.835	1.00
667_H	688_F	0.833	1.00
539_N	578_R	0.833	1.00
165_A	180_F	0.833	1.00
384_Q	427_I	0.832	1.00
269_T	769_Q	0.831	1.00
439_V	484_L	0.831	1.00
112_E	116_T	0.830	1.00
669_G	673_V	0.828	1.00
505_E	518_E	0.827	1.00
422_P	441_Y	0.824	1.00
430_I	433_S	0.822	1.00
530_V	542_A	0.822	1.00
150_A	156_V	0.822	1.00
669_G	715_M	0.821	1.00
288_D	291_F	0.821	1.00
615_R	649_E	0.820	1.00
750_S	753_D	0.818	1.00
447_S	476_G	0.817	1.00
549_G	555_Q	0.812	1.00
692_Q	711_I	0.812	1.00
256_F	283_V	0.812	1.00
159_R	685_N	0.812	1.00
690_S	713_G	0.811	1.00
677_P	680_W	0.810	1.00
314_D	318_L	0.810	1.00
201_P	239_Q	0.809	1.00
621_T	625_Y	0.809	1.00
284_G	294_A	0.807	1.00
300_T	313_I	0.806	1.00
731_D	773_K	0.805	1.00
555_Q	608_V	0.805	1.00
140_I	160_I	0.805	1.00
449_H	474_R	0.804	1.00
373_A	393_Y	0.804	1.00
676_K	724_D	0.803	1.00
622_Q	640_Y	0.803	1.00
676_K	679_N	0.802	1.00
715_M	744_Q	0.802	1.00
353_D	356_R	0.802	1.00
692_Q	712_P	0.801	1.00
236_Y	244_V	0.800	1.00
258_I	293_T	0.800	1.00
569_K	596_N	0.799	1.00
479_A	550_T	0.799	1.00
162_G	229_R	0.797	1.00
694_A	712_P	0.797	1.00
537_S	580_D	0.797	1.00
220_G	280_N	0.796	1.00
623_A	641_A	0.793	1.00
182_I	227_V	0.793	1.00
225_I	247_F	0.792	1.00
253_P	284_G	0.792	1.00
110_P	113_D	0.792	1.00
568_E	598_Q	0.788	1.00
282_M	296_L	0.788	1.00
438_G	485_D	0.786	1.00
439_V	443_Y	0.786	1.00
679_N	724_D	0.785	1.00
234_V	498_G	0.783	1.00
137_R	226_D	0.782	1.00
316_L	320_S	0.781	1.00
183_R	618_G	0.781	1.00
340_E	365_R	0.779	1.00
133_H	137_R	0.778	1.00
719_A	738_V	0.778	1.00
496_T	531_L	0.778	1.00
485_D	527_A	0.778	1.00
314_D	338_D	0.776	1.00
265_Q	282_M	0.776	1.00
270_S	274_N	0.775	1.00
371_K	375_L	0.775	1.00
660_L	666_K	0.775	1.00
286_T	292_G	0.774	1.00
295_L	299_G	0.773	1.00
266_L	269_T	0.772	1.00
508_Q	519_V	0.772	1.00
153_M	156_V	0.771	1.00
280_N	298_S	0.770	1.00
265_Q	771_S	0.768	1.00
484_L	499_M	0.767	1.00
640_Y	674_D	0.767	1.00
442_R	483_Y	0.767	1.00
525_L	546_G	0.766	1.00
743_D	764_R	0.765	1.00
291_F	295_L	0.763	1.00
183_R	591_F	0.763	1.00
252_I	292_G	0.763	1.00
490_I	530_V	0.763	1.00
128_N	133_H	0.762	1.00
712_P	744_Q	0.761	1.00
437_V	441_Y	0.759	1.00
151_T	155_E	0.759	1.00
627_L	637_V	0.758	1.00
432_P	435_H	0.757	1.00
602_N	605_N	0.756	1.00
318_L	322_Y	0.756	1.00
619_L	623_A	0.754	1.00
254_Q	323_A	0.754	1.00
693_F	711_I	0.749	1.00
138_D	160_I	0.749	1.00
584_L	588_M	0.747	1.00
199_G	246_N	0.746	1.00
317_M	335_Q	0.744	1.00
672_G	683_N	0.744	1.00
595_F	598_Q	0.743	1.00
377_Y	389_I	0.742	1.00
425_S	436_E	0.740	1.00
266_L	271_S	0.740	1.00
371_K	395_Q	0.739	1.00
136_A	574_E	0.737	1.00
96_P	102_W	0.737	1.00
268_P	271_S	0.734	1.00
128_N	132_E	0.732	1.00
507_Y	518_E	0.732	1.00
582_G	586_A	0.731	1.00
331_N	388_N	0.731	1.00
681_T	684_L	0.730	1.00
666_K	690_S	0.730	1.00
423_R	438_G	0.729	1.00
616_H	646_V	0.729	1.00
614_T	661_V	0.726	1.00
623_A	627_L	0.722	1.00
420_I	443_Y	0.722	1.00
552_Q	565_V	0.721	1.00
682_F	719_A	0.721	1.00
620_E	644_A	0.717	1.00
693_F	698_N	0.716	1.00
737_G	769_Q	0.716	1.00
490_I	493_W	0.715	1.00
521_Y	567_P	0.715	1.00
147_K	681_T	0.714	1.00
433_S	440_G	0.711	1.00
130_V	139_V	0.709	1.00
219_L	222_M	0.709	1.00
426_Q	439_V	0.708	1.00
638_S	641_A	0.708	1.00
306_R	309_S	0.706	1.00
200_I	374_S	0.706	1.00
255_D	286_T	0.704	1.00
762_Q	765_T	0.704	1.00
102_W	106_P	0.704	1.00
265_Q	269_T	0.703	1.00
181_G	186_N	0.702	1.00
435_H	439_V	0.702	1.00
251_A	333_L	0.702	1.00
271_S	274_N	0.702	1.00
417_V	446_E	0.702	1.00
581_D	584_L	0.702	1.00
478_E	505_E	0.700	1.00
621_T	643_Y	0.699	1.00
268_P	276_K	0.697	1.00
256_F	286_T	0.697	1.00
305_W	763_P	0.697	1.00
494_T	497_P	0.696	1.00
349_R	352_Y	0.695	1.00
267_S	769_Q	0.695	1.00
639_I	643_Y	0.694	1.00
194_T	244_V	0.692	1.00
110_P	114_A	0.691	1.00
256_F	285_G	0.691	1.00
291_F	324_P	0.690	1.00
252_I	321_K	0.688	1.00
294_A	317_M	0.687	1.00
742_F	745_D	0.687	1.00
223_D	253_P	0.686	1.00
107_A	110_P	0.686	1.00
339_G	368_G	0.684	1.00
495_I	499_M	0.684	1.00
519_V	564_N	0.684	1.00
724_D	731_D	0.683	1.00
432_P	490_I	0.683	1.00
286_T	289_N	0.683	1.00
239_Q	479_A	0.682	1.00
504_I	521_Y	0.682	1.00
194_T	240_S	0.681	1.00
575_L	579_Y	0.681	1.00
486_D	497_P	0.680	1.00
477_T	550_T	0.680	1.00
526_P	529_N	0.679	1.00
269_T	277_E	0.679	1.00
348_S	356_R	0.679	1.00
385_H	439_V	0.678	1.00
292_G	329_T	0.678	1.00
523_A	546_G	0.677	1.00
99_N	102_W	0.677	1.00
518_E	521_Y	0.677	1.00
552_Q	555_Q	0.676	1.00
599_Y	608_V	0.675	1.00
401_Y	410_L	0.675	1.00
677_P	682_F	0.675	1.00
585_T	626_D	0.675	1.00
322_Y	325_D	0.674	1.00
164_S	665_P	0.674	1.00
492_N	536_D	0.674	1.00
228_V	244_V	0.674	1.00
254_Q	286_T	0.673	1.00
269_T	273_N	0.672	1.00
228_V	236_Y	0.671	1.00
565_V	599_Y	0.671	1.00
527_A	543_N	0.668	1.00
229_R	622_Q	0.667	1.00
354_A	357_W	0.666	1.00
397_L	414_N	0.666	1.00
385_H	437_V	0.664	1.00
128_N	487_K	0.664	1.00
253_P	257_G	0.663	1.00
492_N	533_H	0.663	1.00
419_G	444_L	0.660	1.00
675_Y	682_F	0.660	1.00
420_I	424_Y	0.658	1.00
717_W	738_V	0.656	1.00
327_V	381_P	0.656	1.00
593_I	616_H	0.654	1.00
733_N	736_F	0.653	1.00
146_A	771_S	0.653	1.00
438_G	487_K	0.652	1.00
136_A	589_G	0.652	1.00
235_R	438_G	0.651	1.00
374_S	392_F	0.650	1.00
138_D	161_P	0.649	1.00
479_A	504_I	0.648	1.00
768_M	771_S	0.648	1.00
437_V	484_L	0.647	1.00
723_Y	726_G	0.646	1.00
255_D	258_I	0.646	1.00
283_V	286_T	0.644	1.00
671_L	715_M	0.644	1.00
730_A	772_L	0.643	1.00
158_N	687_D	0.640	1.00
725_F	730_A	0.639	1.00
418_R	422_P	0.638	1.00
666_K	691_S	0.638	1.00
250_R	282_M	0.636	1.00
379_F	382_D	0.636	1.00
231_G	547_S	0.634	1.00
319_K	333_L	0.633	1.00
185_L	595_F	0.633	1.00
195_V	214_L	0.633	1.00
144_D	148_T	0.632	1.00
195_V	247_F	0.631	1.00
381_P	385_H	0.630	1.00
267_S	270_S	0.629	1.00
301_R	310_A	0.629	1.00
113_D	116_T	0.629	1.00
99_N	104_L	0.628	1.00
313_I	339_G	0.627	1.00
96_P	104_L	0.627	1.00
418_R	445_N	0.626	1.00
433_S	442_R	0.626	1.00
417_V	444_L	0.624	1.00
416_W	447_S	0.622	1.00
181_G	192_R	0.622	1.00
435_H	438_G	0.621	1.00
686_S	742_F	0.621	1.00
599_Y	610_A	0.619	1.00
153_M	222_M	0.618	1.00
627_L	635_D	0.618	1.00
230_G	574_E	0.617	1.00
251_A	329_T	0.617	1.00
98_G	104_L	0.614	1.00
258_I	285_G	0.612	1.00
98_G	102_W	0.611	1.00
429_M	432_P	0.611	1.00
291_F	318_L	0.610	1.00
535_T	579_Y	0.609	1.00
657_Y	661_V	0.609	1.00
648_A	664_S	0.609	1.00
357_W	362_P	0.609	1.00
626_D	636_N	0.608	1.00
254_Q	258_I	0.608	1.00
321_K	324_P	0.605	1.00
281_L	297_Y	0.604	1.00
435_H	442_R	0.604	1.00
528_L	532_Y	0.604	1.00
690_S	715_M	0.604	1.00
311_T	339_G	0.603	1.00
585_T	588_M	0.602	1.00
766_L	770_G	0.601	1.00
483_Y	500_R	0.601	1.00
201_P	419_G	0.600	1.00
383_S	428_F	0.600	1.00
349_R	353_D	0.599	1.00
192_R	568_E	0.598	1.00
228_V	232_G	0.598	1.00
163_V	180_F	0.597	1.00
276_K	301_R	0.597	1.00
348_S	352_Y	0.596	1.00
390_Q	423_R	0.596	1.00
662_P	693_F	0.596	1.00
595_F	614_T	0.595	1.00
269_T	275_P	0.595	1.00
444_L	479_A	0.594	1.00
497_P	501_F	0.594	1.00
328_H	332_S	0.593	1.00
304_D	309_S	0.591	1.00
715_M	742_F	0.590	1.00
647_N	666_K	0.590	1.00
185_L	616_H	0.589	1.00
446_E	477_T	0.588	1.00
283_V	293_T	0.588	1.00
252_I	294_A	0.588	1.00
668_K	689_Q	0.587	1.00
136_A	229_R	0.587	1.00
155_E	739_K	0.587	1.00
508_Q	518_E	0.587	1.00
131_F	580_D	0.586	1.00
566_E	569_K	0.584	1.00
268_P	272_Q	0.582	1.00
541_Y	587_E	0.582	1.00
270_S	275_P	0.582	1.00
625_Y	637_V	0.581	1.00
156_V	219_L	0.581	1.00
231_G	545_E	0.580	1.00
679_N	726_G	0.580	1.00
193_S	242_G	0.580	1.00
269_T	272_Q	0.580	1.00
275_P	302_G	0.578	1.00
682_F	686_S	0.578	1.00
290_G	325_D	0.578	1.00
356_R	362_P	0.576	1.00
345_G	348_S	0.575	1.00
770_G	774_F	0.575	1.00
353_D	358_Q	0.574	1.00
488_I	495_I	0.574	1.00
134_A	496_T	0.574	1.00
150_A	155_E	0.574	1.00
626_D	634_L	0.573	1.00
721_V	725_F	0.573	1.00
389_I	418_R	0.572	1.00
505_E	520_S	0.571	1.00
220_G	296_L	0.571	1.00
428_F	435_H	0.570	1.00
622_Q	642_S	0.570	1.00
379_F	387_F	0.568	1.00
424_Y	439_V	0.567	1.00
684_L	741_I	0.567	1.00
482_W	522_N	0.566	1.00
369_R	397_L	0.566	1.00
185_L	192_R	0.566	1.00
552_Q	556_I	0.566	1.00
450_E	473_T	0.566	1.00
111_K	115_L	0.564	1.00
290_G	326_E	0.563	1.00
354_A	358_Q	0.563	1.00
161_P	229_R	0.562	1.00
614_T	648_A	0.561	1.00
130_V	137_R	0.561	1.00
202_V	372_L	0.561	1.00
577_T	586_A	0.561	1.00
131_F	533_H	0.560	1.00
234_V	485_D	0.558	1.00
559_A	563_G	0.557	1.00
527_A	545_E	0.557	1.00
248_V	251_A	0.556	1.00
573_W	590_L	0.556	1.00
307_E	310_A	0.556	1.00
308_H	312_R	0.555	1.00
166_P	179_N	0.555	1.00
350_A	353_D	0.554	1.00
271_S	276_K	0.554	1.00
523_A	567_P	0.554	1.00
680_W	684_L	0.554	1.00
301_R	314_D	0.554	1.00
213_S	216_P	0.553	1.00
438_G	442_R	0.553	1.00
355_D	358_Q	0.552	1.00
221_N	315_D	0.552	1.00
415_Y	448_T	0.552	1.00
725_F	731_D	0.551	1.00
347_L	351_D	0.551	1.00
489_D	533_H	0.551	1.00
351_D	354_A	0.550	1.00
433_S	438_G	0.550	1.00
252_I	293_T	0.550	1.00
560_V	607_T	0.548	1.00
547_S	572_T	0.548	1.00
424_Y	428_F	0.547	1.00
364_D	400_G	0.546	1.00
433_S	437_V	0.543	1.00
161_P	164_S	0.542	1.00
485_D	498_G	0.542	1.00
719_A	736_F	0.541	1.00
413_R	450_E	0.541	1.00
253_P	256_F	0.540	1.00
358_Q	362_P	0.540	1.00
185_L	242_G	0.540	1.00
99_N	103_T	0.540	1.00
548_F	569_K	0.540	1.00
179_N	192_R	0.540	1.00
565_V	610_A	0.540	1.00
307_E	312_R	0.539	1.00
128_N	131_F	0.539	1.00
116_T	119_G	0.539	1.00
534_L	537_S	0.538	1.00
376_G	379_F	0.537	1.00
352_Y	355_D	0.537	1.00
436_E	439_V	0.537	1.00
670_T	685_N	0.536	1.00
671_L	686_S	0.535	1.00
381_P	384_Q	0.535	1.00
102_W	107_A	0.534	1.00
493_W	534_L	0.534	1.00
97_L	104_L	0.534	1.00
147_K	676_K	0.533	1.00
255_D	289_N	0.532	1.00
320_S	332_S	0.532	1.00
102_W	108_P	0.532	1.00
273_N	276_K	0.530	1.00
101_S	106_P	0.529	1.00
716_L	743_D	0.529	1.00
144_D	640_Y	0.529	1.00
574_E	620_E	0.529	1.00
695_D	699_T	0.529	1.00
333_L	376_G	0.529	1.00
156_V	160_I	0.528	1.00
641_A	645_Y	0.528	1.00
374_S	390_Q	0.528	1.00
435_H	489_D	0.527	1.00
627_L	636_N	0.527	1.00
345_G	349_R	0.524	1.00
188_R	598_Q	0.524	1.00
399_S	410_L	0.524	1.00
377_Y	381_P	0.523	1.00
543_N	574_E	0.522	1.00
419_G	442_R	0.522	1.00
351_D	356_R	0.522	1.00
528_L	531_L	0.520	1.00
659_N	698_N	0.520	1.00
519_V	566_E	0.519	1.00
425_S	438_G	0.519	1.00
385_H	389_I	0.519	1.00
574_E	578_R	0.518	1.00
151_T	300_T	0.517	1.00
150_A	153_M	0.517	1.00
241_V	547_S	0.517	1.00
135_G	527_A	0.516	1.00
327_V	382_D	0.516	1.00
571_R	592_L	0.516	1.00
240_S	547_S	0.516	1.00
579_Y	587_E	0.515	1.00
452_R	471_R	0.515	1.00
721_V	736_F	0.515	1.00
266_L	272_Q	0.513	1.00
673_V	686_S	0.513	1.00
679_N	725_F	0.513	1.00
253_P	292_G	0.512	1.00
720_R	767_Y	0.512	1.00
575_L	592_L	0.512	1.00
257_G	284_G	0.511	1.00
101_S	107_A	0.511	1.00
196_L	236_Y	0.510	1.00
665_P	689_Q	0.509	1.00
351_D	355_D	0.509	1.00
258_I	266_L	0.508	1.00
389_I	393_Y	0.508	1.00
291_F	323_A	0.507	1.00
185_L	593_I	0.506	1.00
379_F	383_S	0.506	1.00
399_S	412_P	0.506	1.00
694_A	711_I	0.506	1.00
720_R	733_N	0.506	1.00
419_G	423_R	0.506	1.00
646_V	668_K	0.505	1.00
158_N	718_G	0.505	1.00
272_Q	766_L	0.505	1.00
624_R	627_L	0.505	1.00
617_T	645_Y	0.505	1.00
662_P	665_P	0.504	1.00
214_L	247_F	0.504	1.00
598_Q	612_G	0.504	1.00
480_H	505_E	0.504	1.00
543_N	572_T	0.503	1.00
250_R	294_A	0.503	1.00
318_L	321_K	0.502	1.00
597_N	610_A	0.502	1.00
127_E	130_V	0.502	1.00
134_A	137_R	0.502	1.00
732_L	768_M	0.501	1.00
387_F	420_I	0.501	1.00
480_H	522_N	0.500	1.00
375_L	391_G	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1kmoA	1	0.8398	100	0.204	Contact Map
2w16A	1	0.9018	100	0.319	Contact Map
3cslA	1	0.7907	100	0.328	Contact Map
3efmA	1	0.7145	100	0.341	Contact Map
3qlbA	1	0.8101	100	0.344	Contact Map
4cu4A	1	0.814	100	0.346	Contact Map
1xkwA	1	0.7829	100	0.35	Contact Map
2gufA	1	0.7093	100	0.362	Contact Map
2hdiA	1	0.7016	100	0.365	Contact Map
3v8xA	1	0.8023	100	0.377	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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