GLPD - ECOLI - GREMLIN Contacts

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GLPD - Aerobic glycerol-3-phosphate dehydrogenase

UniProt:	P13035	Sequences: METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYEFRLVSEALAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIRIGLFMYDHLGKRTSLPGSTGLRFGANSVLKPEIKRGFEYSDCWVDDARLVLANAQMVVRKGGEVLTRTRATSARRENGLWIVEAEDIDTGKKYSWQARGLVNATGPWVKQFFDDGMHLPSPYGIRLIKGSHIVVPRVHTQKQAYILQNEDKRIVFVIPWMDEFSIIGTTDVEYKGDPKAVKIEESEINYLLNVYNTHFKKQLSRDDIVWTYSGVRPLCDDESDSPQAITRDYTLDIHDENGKAPLLSVFGGKLTTYRKLAEHALEKLTPYYQGIGPAWTKESVLPGGAIEGDRDDYAARLRRRYPFLTESLARHYARTYGSNSELLLGNAGTVSDLGEDFGHEFYEAELKYLVDHEWVRRADDALWRRTKQGMWLNADQQSRVSQWLVEYTQQRLSLAS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10394
Length:	501 (475)
Sequences:	3648 (2403)
Seq/√Len:	110.3

ECOLI - GLPD GLPA
BACSU - GLPD YHFW
HALSA - Q9HNS4
SULSO - Q97VT4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
7_I	184_V	5.748	1.00
4_K	30_L	4.129	1.00
34_A	171_R	3.994	1.00
128_N	138_G	3.941	1.00
32_L	186_A	3.776	1.00
159_V	164_G	3.639	1.00
187_E	194_K	3.533	1.00
236_V	268_I	3.481	1.00
286_E	306_R	3.392	1.00
245_A	248_L	3.311	1.00
290_N	294_N	3.275	1.00
171_R	189_I	3.270	1.00
32_L	172_A	3.263	1.00
186_A	197_W	3.208	1.00
185_E	194_K	3.117	1.00
17_G	358_Y	3.098	1.00
35_Q	39_C	3.063	1.00
170_T	186_A	3.010	1.00
7_I	199_A	2.991	1.00
185_E	196_S	2.978	1.00
4_K	165_E	2.891	1.00
37_L	168_T	2.833	1.00
7_I	197_W	2.829	1.00
190_D	461_R	2.821	1.00
290_N	306_R	2.814	1.00
174_S	185_E	2.759	1.00
232_S	292_L	2.723	1.00
460_V	466_A	2.710	1.00
188_D	191_T	2.705	1.00
16_A	156_A	2.646	1.00
203_V	369_L	2.616	1.00
173_T	187_E	2.582	1.00
19_A	29_V	2.533	1.00
171_R	187_E	2.440	1.00
448_E	452_K	2.376	1.00
176_R	183_I	2.366	1.00
448_E	488_W	2.362	1.00
30_L	197_W	2.326	1.00
11_G	31_M	2.304	1.00
7_I	30_L	2.259	1.00
297_N	304_L	2.255	1.00
427_L	457_H	2.249	1.00
206_T	213_F	2.230	1.00
451_L	466_A	2.192	1.00
227_R	274_E	2.103	1.00
9_I	213_F	2.088	1.00
156_A	166_V	2.086	1.00
13_I	155_N	2.085	1.00
424_N	453_Y	2.062	1.00
420_T	471_T	2.055	1.00
244_Q	248_L	1.987	1.00
286_E	290_N	1.982	1.00
18_I	366_L	1.917	1.00
157_Q	424_N	1.872	1.00
34_A	280_K	1.871	1.00
176_R	196_S	1.852	1.00
440_E	448_E	1.847	1.00
160_V	166_V	1.828	1.00
175_A	202_L	1.812	1.00
478_N	481_Q	1.802	1.00
8_V	18_I	1.780	1.00
451_L	485_V	1.779	1.00
11_G	33_E	1.779	1.00
6_L	201_G	1.774	1.00
16_A	152_V	1.768	1.00
293_L	304_L	1.702	1.00
125_F	128_N	1.701	1.00
5_D	200_R	1.694	1.00
284_I	312_T	1.690	1.00
161_R	424_N	1.681	1.00
201_G	369_L	1.680	1.00
176_R	182_W	1.679	1.00
32_L	184_V	1.676	1.00
24_G	380_W	1.658	1.00
20_A	158_M	1.635	1.00
405_R	426_E	1.616	1.00
338_I	372_Y	1.615	1.00
230_K	273_V	1.614	1.00
289_I	312_T	1.612	1.00
7_I	32_L	1.607	1.00
181_L	202_L	1.607	1.00
21_D	381_T	1.607	1.00
454_L	460_V	1.595	1.00
454_L	466_A	1.594	1.00
289_I	306_R	1.593	1.00
24_G	384_S	1.592	1.00
121_T	140_E	1.590	1.00
18_I	203_V	1.590	1.00
173_T	185_E	1.586	1.00
37_L	156_A	1.584	1.00
177_R	180_G	1.574	1.00
14_N	350_V	1.569	1.00
173_T	194_K	1.569	1.00
37_L	166_V	1.564	1.00
21_D	25_R	1.564	1.00
468_W	474_G	1.563	1.00
258_V	266_S	1.557	1.00
467_L	482_Q	1.541	1.00
284_I	289_I	1.535	1.00
30_L	167_L	1.521	1.00
410_T	413_L	1.518	1.00
27_L	376_I	1.515	1.00
431_N	452_K	1.500	1.00
293_L	306_R	1.490	1.00
258_V	296_Y	1.482	1.00
432_A	439_G	1.480	1.00
441_D	445_E	1.480	1.00
167_L	195_Y	1.474	1.00
176_R	185_E	1.473	1.00
428_L	449_A	1.471	1.00
213_F	216_D	1.468	1.00
186_A	195_Y	1.467	1.00
175_A	213_F	1.465	1.00
440_E	484_R	1.464	1.00
230_K	275_Y	1.464	1.00
32_L	197_W	1.459	1.00
27_L	370_T	1.458	1.00
293_L	297_N	1.457	1.00
306_R	309_I	1.455	1.00
20_A	155_N	1.448	1.00
155_N	358_Y	1.438	1.00
348_L	369_L	1.437	1.00
24_G	162_K	1.424	1.00
86_R	142_S	1.420	1.00
170_T	195_Y	1.417	1.00
297_N	303_Q	1.416	1.00
227_R	321_D	1.413	1.00
267_I	313_Y	1.410	1.00
231_G	317_R	1.407	1.00
38_A	152_V	1.391	1.00
232_S	273_V	1.369	1.00
178_E	183_I	1.369	1.00
158_M	162_K	1.369	1.00
363_E	382_K	1.368	1.00
40_A	44_A	1.366	1.00
368_K	371_P	1.363	1.00
92_R	135_I	1.362	1.00
38_A	149_A	1.357	1.00
187_E	192_G	1.353	1.00
480_D	484_R	1.353	1.00
172_A	184_V	1.344	1.00
6_L	22_A	1.342	1.00
427_L	430_G	1.326	1.00
245_A	249_Q	1.315	0.99
441_D	447_Y	1.301	0.99
19_A	164_G	1.299	0.99
151_L	355_L	1.286	0.99
22_A	366_L	1.281	0.99
11_G	37_L	1.275	0.99
147_D	420_T	1.267	0.99
167_L	170_T	1.260	0.99
46_S	259_I	1.257	0.99
201_G	348_L	1.254	0.99
482_Q	486_S	1.240	0.99
466_A	489_L	1.239	0.99
210_V	226_I	1.236	0.99
237_P	264_E	1.230	0.99
403_R	411_E	1.226	0.99
65_S	69_A	1.221	0.99
296_Y	304_L	1.214	0.99
217_G	339_H	1.214	0.99
18_I	362_A	1.204	0.99
208_P	316_V	1.202	0.99
18_I	205_A	1.200	0.99
5_D	27_L	1.190	0.99
201_G	373_Y	1.190	0.99
398_Y	418_A	1.179	0.99
481_Q	485_V	1.177	0.99
435_V	438_L	1.173	0.99
398_Y	426_E	1.165	0.99
86_R	140_E	1.164	0.99
4_K	28_S	1.161	0.99
370_T	376_I	1.156	0.99
82_A	144_C	1.148	0.99
238_R	263_D	1.144	0.99
246_Y	249_Q	1.141	0.99
74_L	82_A	1.138	0.98
174_S	216_D	1.135	0.98
19_A	159_V	1.135	0.98
158_M	161_R	1.134	0.98
362_A	379_A	1.134	0.98
108_Y	112_G	1.131	0.98
401_R	405_R	1.129	0.98
21_D	379_A	1.126	0.98
420_T	450_E	1.122	0.98
62_R	66_E	1.114	0.98
452_K	456_D	1.110	0.98
60_E	63_L	1.110	0.98
452_K	488_W	1.109	0.98
251_E	298_T	1.105	0.98
31_M	37_L	1.105	0.98
88_R	138_G	1.103	0.98
78_A	386_L	1.103	0.98
319_L	354_K	1.097	0.98
368_K	372_Y	1.092	0.98
338_I	348_L	1.091	0.98
442_F	451_L	1.083	0.98
234_I	268_I	1.082	0.98
66_E	360_K	1.078	0.98
230_K	285_E	1.071	0.98
188_D	193_K	1.066	0.98
370_T	373_Y	1.064	0.98
403_R	414_A	1.062	0.98
205_A	350_V	1.062	0.98
58_H	329_A	1.060	0.98
271_T	317_R	1.060	0.98
175_A	216_D	1.059	0.98
336_L	364_H	1.053	0.97
124_R	127_A	1.053	0.97
485_V	488_W	1.051	0.97
398_Y	402_L	1.051	0.97
275_Y	278_D	1.041	0.97
244_Q	247_I	1.041	0.97
278_D	281_A	1.039	0.97
83_F	145_W	1.038	0.97
476_W	482_Q	1.032	0.97
240_H	308_D	1.032	0.97
28_S	165_E	1.032	0.97
235_V	311_W	1.025	0.97
7_I	202_L	1.022	0.97
411_E	415_R	1.021	0.97
21_D	362_A	1.014	0.97
431_N	456_D	1.013	0.97
453_Y	457_H	1.009	0.97
178_E	198_Q	1.009	0.97
390_A	423_S	1.008	0.97
444_H	473_Q	1.006	0.97
41_T	208_P	1.002	0.97
48_L	145_W	1.002	0.97
104_G	109_D	1.001	0.97
348_L	368_K	0.997	0.97
96_R	99_W	0.987	0.96
32_L	170_T	0.987	0.96
175_A	181_L	0.984	0.96
133_P	301_K	0.983	0.96
169_R	461_R	0.980	0.96
231_G	271_T	0.976	0.96
434_T	437_D	0.971	0.96
183_I	198_Q	0.967	0.96
477_L	482_Q	0.964	0.96
417_Y	428_L	0.960	0.96
338_I	368_K	0.957	0.96
468_W	476_W	0.948	0.95
178_E	182_W	0.934	0.95
74_L	151_L	0.933	0.95
66_E	333_D	0.931	0.95
63_L	67_A	0.931	0.95
124_R	128_N	0.928	0.95
156_A	168_T	0.927	0.95
55_Y	354_K	0.925	0.95
4_K	7_I	0.924	0.95
17_G	362_A	0.923	0.95
172_A	213_F	0.922	0.95
275_Y	316_V	0.921	0.95
83_F	419_R	0.917	0.94
80_H	388_G	0.916	0.94
128_N	131_L	0.912	0.94
14_N	361_L	0.909	0.94
70_E	359_R	0.905	0.94
467_L	486_S	0.903	0.94
322_D	330_I	0.900	0.94
350_V	365_A	0.900	0.94
5_D	28_S	0.899	0.94
175_A	184_V	0.898	0.94
23_A	29_V	0.898	0.94
35_Q	40_A	0.897	0.94
477_L	481_Q	0.896	0.94
161_R	387_P	0.895	0.94
69_A	360_K	0.894	0.94
199_A	202_L	0.886	0.93
377_G	380_W	0.886	0.93
438_L	449_A	0.883	0.93
449_A	452_K	0.883	0.93
184_V	199_A	0.883	0.93
396_D	399_A	0.882	0.93
385_V	389_G	0.881	0.93
350_V	361_L	0.881	0.93
54_R	270_T	0.876	0.93
19_A	166_V	0.873	0.93
183_I	196_S	0.871	0.93
35_Q	169_R	0.870	0.93
73_V	77_M	0.868	0.93
237_P	310_V	0.867	0.93
256_V	295_V	0.863	0.92
123_L	128_N	0.863	0.92
174_S	194_K	0.862	0.92
170_T	197_W	0.861	0.92
430_G	434_T	0.861	0.92
201_G	372_Y	0.858	0.92
49_I	74_L	0.857	0.92
428_L	432_A	0.853	0.92
397_D	400_A	0.852	0.92
398_Y	401_R	0.850	0.92
157_Q	160_V	0.848	0.92
432_A	449_A	0.845	0.92
415_R	419_R	0.844	0.92
248_L	258_V	0.844	0.92
132_K	303_Q	0.841	0.91
369_L	373_Y	0.841	0.91
481_Q	484_R	0.841	0.91
363_E	379_A	0.840	0.91
414_A	425_S	0.839	0.91
424_N	427_L	0.839	0.91
329_A	335_T	0.835	0.91
64_V	68_L	0.835	0.91
231_G	315_G	0.833	0.91
102_R	106_F	0.832	0.91
446_F	450_E	0.831	0.91
211_K	214_F	0.826	0.91
152_V	355_L	0.824	0.91
85_M	145_W	0.824	0.91
317_R	332_R	0.824	0.91
373_Y	376_I	0.823	0.91
183_I	346_P	0.823	0.91
109_D	112_G	0.823	0.91
52_G	55_Y	0.820	0.90
190_D	193_K	0.819	0.90
285_E	288_E	0.819	0.90
399_A	402_L	0.818	0.90
317_R	354_K	0.817	0.90
401_R	404_R	0.817	0.90
76_K	383_E	0.817	0.90
336_L	365_A	0.816	0.90
21_D	367_E	0.816	0.90
320_C	335_T	0.814	0.90
367_E	381_T	0.814	0.90
430_G	433_G	0.809	0.90
406_Y	429_L	0.808	0.90
367_E	379_A	0.808	0.90
432_A	438_L	0.807	0.90
54_R	354_K	0.806	0.90
271_T	354_K	0.805	0.90
279_P	282_V	0.801	0.89
431_N	457_H	0.798	0.89
23_A	162_K	0.797	0.89
243_K	248_L	0.795	0.89
17_G	21_D	0.792	0.89
31_M	156_A	0.790	0.89
239_V	302_K	0.787	0.89
8_V	217_G	0.786	0.88
334_Y	364_H	0.785	0.88
209_W	279_P	0.784	0.88
37_L	459_W	0.782	0.88
441_D	481_Q	0.782	0.88
162_K	384_S	0.782	0.88
187_E	191_T	0.782	0.88
189_I	193_K	0.776	0.88
66_E	364_H	0.774	0.88
78_A	81_I	0.773	0.88
8_V	20_A	0.770	0.87
432_A	436_S	0.768	0.87
400_A	404_R	0.767	0.87
50_H	54_R	0.767	0.87
431_N	449_A	0.766	0.87
79_P	389_G	0.766	0.87
22_A	27_L	0.766	0.87
45_S	148_D	0.766	0.87
122_G	137_R	0.765	0.87
443_G	484_R	0.765	0.87
363_E	367_E	0.764	0.87
446_F	471_T	0.764	0.87
380_W	384_S	0.760	0.87
64_V	108_Y	0.759	0.87
425_S	429_L	0.755	0.86
436_S	441_D	0.755	0.86
23_A	164_G	0.754	0.86
409_L	414_A	0.754	0.86
268_I	292_L	0.751	0.86
212_Q	279_P	0.750	0.86
319_L	332_R	0.749	0.86
233_H	271_T	0.748	0.86
154_A	386_L	0.747	0.86
25_R	367_E	0.747	0.86
284_I	288_E	0.746	0.86
439_G	442_F	0.744	0.86
227_R	330_I	0.741	0.85
463_A	467_L	0.741	0.85
402_L	425_S	0.739	0.85
191_T	194_K	0.739	0.85
189_I	480_D	0.738	0.85
24_G	158_M	0.737	0.85
123_L	140_E	0.737	0.85
268_I	296_Y	0.736	0.85
363_E	381_T	0.736	0.85
233_H	272_D	0.734	0.85
62_R	333_D	0.731	0.85
22_A	29_V	0.731	0.85
360_K	364_H	0.729	0.84
482_Q	485_V	0.728	0.84
106_F	110_H	0.728	0.84
244_Q	249_Q	0.728	0.84
317_R	353_G	0.727	0.84
416_H	450_E	0.721	0.84
211_K	215_D	0.719	0.84
435_V	448_E	0.719	0.84
452_K	455_V	0.717	0.83
89_L	101_I	0.716	0.83
29_V	164_G	0.715	0.83
413_L	447_Y	0.715	0.83
300_F	303_Q	0.714	0.83
271_T	318_P	0.713	0.83
348_L	365_A	0.713	0.83
270_T	354_K	0.712	0.83
92_R	134_E	0.712	0.83
108_Y	111_L	0.711	0.83
467_L	489_L	0.711	0.83
273_V	288_E	0.708	0.83
417_Y	425_S	0.706	0.82
478_N	484_R	0.706	0.82
294_N	298_T	0.705	0.82
451_L	489_L	0.705	0.82
326_S	329_A	0.705	0.82
6_L	366_L	0.703	0.82
271_T	332_R	0.703	0.82
416_H	446_F	0.702	0.82
230_K	314_S	0.701	0.82
104_G	111_L	0.700	0.82
204_N	349_S	0.698	0.82
231_G	354_K	0.695	0.81
417_Y	447_Y	0.695	0.81
425_S	428_L	0.695	0.81
318_P	354_K	0.695	0.81
476_W	481_Q	0.694	0.81
485_V	489_L	0.694	0.81
262_M	419_R	0.692	0.81
106_F	120_S	0.691	0.81
20_A	24_G	0.691	0.81
232_S	284_I	0.690	0.81
159_V	362_A	0.689	0.81
391_I	423_S	0.687	0.81
252_D	270_T	0.686	0.81
242_Q	248_L	0.686	0.81
235_V	313_Y	0.686	0.81
396_D	400_A	0.684	0.80
274_E	330_I	0.683	0.80
229_I	319_L	0.683	0.80
64_V	319_L	0.683	0.80
23_A	159_V	0.682	0.80
297_N	305_S	0.682	0.80
395_R	398_Y	0.682	0.80
12_G	15_G	0.682	0.80
190_D	462_R	0.676	0.80
183_I	199_A	0.675	0.80
92_R	131_L	0.675	0.80
104_G	107_M	0.675	0.80
10_G	15_G	0.674	0.79
76_K	115_T	0.671	0.79
254_R	257_F	0.670	0.79
104_G	108_Y	0.669	0.79
466_A	485_V	0.668	0.79
210_V	349_S	0.667	0.79
140_E	144_C	0.666	0.79
60_E	333_D	0.664	0.78
217_G	345_A	0.664	0.78
402_L	414_A	0.664	0.78
95_L	98_A	0.664	0.78
20_A	384_S	0.664	0.78
254_R	354_K	0.664	0.78
81_I	154_A	0.663	0.78
6_L	29_V	0.661	0.78
479_A	483_S	0.661	0.78
360_K	363_E	0.661	0.78
9_I	172_A	0.660	0.78
483_S	487_Q	0.659	0.78
132_K	135_I	0.658	0.78
415_R	434_T	0.655	0.78
187_E	193_K	0.655	0.78
291_Y	300_F	0.655	0.78
49_I	131_L	0.654	0.77
400_A	411_E	0.654	0.77
41_T	354_K	0.653	0.77
138_G	247_I	0.652	0.77
478_N	482_Q	0.651	0.77
8_V	366_L	0.650	0.77
29_V	166_V	0.650	0.77
257_F	270_T	0.650	0.77
91_H	95_L	0.649	0.77
434_T	452_K	0.648	0.77
95_L	101_I	0.648	0.77
287_S	290_N	0.647	0.77
103_I	107_M	0.646	0.77
439_G	448_E	0.646	0.77
214_F	347_L	0.646	0.77
75_L	82_A	0.645	0.76
21_D	363_E	0.645	0.76
184_V	197_W	0.644	0.76
46_S	257_F	0.643	0.76
435_V	441_D	0.642	0.76
203_V	366_L	0.641	0.76
443_G	446_F	0.640	0.76
252_D	257_F	0.640	0.76
481_Q	486_S	0.637	0.76
212_Q	215_D	0.637	0.76
181_L	198_Q	0.636	0.75
321_D	325_D	0.636	0.75
18_I	365_A	0.636	0.75
302_K	452_K	0.631	0.75
277_G	281_A	0.630	0.75
332_R	354_K	0.630	0.75
55_Y	317_R	0.630	0.75
146_V	355_L	0.628	0.75
413_L	445_E	0.628	0.75
434_T	456_D	0.626	0.74
129_S	135_I	0.626	0.74
6_L	371_P	0.623	0.74
381_T	388_G	0.622	0.74
271_T	319_L	0.621	0.74
235_V	267_I	0.621	0.74
210_V	351_F	0.621	0.74
404_R	410_T	0.620	0.74
51_G	56_L	0.620	0.74
272_D	354_K	0.619	0.73
50_H	354_K	0.619	0.73
159_V	166_V	0.618	0.73
30_L	186_A	0.618	0.73
251_E	294_N	0.615	0.73
25_R	379_A	0.614	0.73
25_R	381_T	0.613	0.73
410_T	414_A	0.613	0.73
47_K	148_D	0.613	0.73
446_F	451_L	0.611	0.73
50_H	55_Y	0.611	0.73
55_Y	231_G	0.610	0.72
339_H	344_K	0.610	0.72
91_H	101_I	0.609	0.72
56_L	64_V	0.608	0.72
55_Y	319_L	0.607	0.72
243_K	246_Y	0.607	0.72
176_R	198_Q	0.606	0.72
183_I	202_L	0.606	0.72
142_S	145_W	0.606	0.72
480_D	483_S	0.605	0.72
432_A	435_V	0.603	0.72
428_L	447_Y	0.603	0.72
93_P	98_A	0.602	0.71
204_N	210_V	0.602	0.71
233_H	254_R	0.601	0.71
397_D	404_R	0.599	0.71
181_L	347_L	0.598	0.71
455_V	460_V	0.598	0.71
6_L	18_I	0.596	0.71
44_A	313_Y	0.596	0.71
140_E	143_D	0.596	0.71
402_L	426_E	0.595	0.71
176_R	181_L	0.593	0.70
359_R	381_T	0.592	0.70
420_T	473_Q	0.592	0.70
14_N	362_A	0.590	0.70
437_D	440_E	0.590	0.70
405_R	433_G	0.588	0.70
219_H	222_S	0.588	0.70
430_G	457_H	0.587	0.70
436_S	440_E	0.587	0.70
366_L	379_A	0.587	0.70
247_I	255_I	0.587	0.70
27_L	374_Q	0.585	0.69
42_S	148_D	0.585	0.69
191_T	376_I	0.585	0.69
231_G	319_L	0.583	0.69
86_R	91_H	0.583	0.69
84_P	142_S	0.582	0.69
426_E	430_G	0.581	0.69
30_L	165_E	0.580	0.69
170_T	173_T	0.579	0.68
91_H	139_F	0.578	0.68
77_M	358_Y	0.578	0.68
484_R	488_W	0.578	0.68
193_K	440_E	0.577	0.68
401_R	426_E	0.576	0.68
101_I	104_G	0.576	0.68
446_F	454_L	0.576	0.68
76_K	116_S	0.575	0.68
240_H	258_V	0.574	0.68
171_R	212_Q	0.573	0.68
446_F	466_A	0.572	0.68
232_S	312_T	0.572	0.68
358_Y	381_T	0.572	0.68
121_T	127_A	0.572	0.68
38_A	43_S	0.570	0.67
451_L	460_V	0.567	0.67
441_D	444_H	0.566	0.67
189_I	192_G	0.566	0.67
234_I	328_Q	0.565	0.67
396_D	415_R	0.565	0.67
273_V	285_E	0.565	0.67
273_V	287_S	0.565	0.67
191_T	461_R	0.565	0.67
463_A	489_L	0.564	0.66
189_I	194_K	0.562	0.66
326_S	330_I	0.560	0.66
432_A	437_D	0.560	0.66
8_V	29_V	0.560	0.66
215_D	224_Y	0.560	0.66
272_D	317_R	0.559	0.66
156_A	160_V	0.558	0.66
69_A	363_E	0.558	0.66
269_G	315_G	0.558	0.66
455_V	463_A	0.557	0.66
400_A	407_P	0.557	0.66
52_G	354_K	0.556	0.65
286_E	289_I	0.554	0.65
4_K	186_A	0.554	0.65
65_S	382_K	0.554	0.65
473_Q	485_V	0.551	0.65
58_H	273_V	0.551	0.65
50_H	356_T	0.550	0.65
399_A	415_R	0.549	0.64
409_L	413_L	0.549	0.64
428_L	431_N	0.548	0.64
176_R	179_N	0.547	0.64
432_A	447_Y	0.547	0.64
160_V	459_W	0.546	0.64
236_V	304_L	0.546	0.64
438_L	442_F	0.545	0.64
108_Y	141_Y	0.543	0.64
72_E	84_P	0.543	0.64
435_V	439_G	0.543	0.64
212_Q	216_D	0.543	0.64
88_R	123_L	0.540	0.63
105_L	108_Y	0.540	0.63
229_I	272_D	0.539	0.63
433_G	436_S	0.538	0.63
464_D	468_W	0.537	0.63
182_W	198_Q	0.537	0.63
438_L	448_E	0.536	0.63
463_A	486_S	0.535	0.62
51_G	356_T	0.535	0.62
157_Q	161_R	0.534	0.62
400_A	415_R	0.534	0.62
78_A	359_R	0.531	0.62
334_Y	361_L	0.531	0.62
369_L	374_Q	0.531	0.62
172_A	216_D	0.530	0.62
30_L	34_A	0.530	0.62
234_I	289_I	0.530	0.62
16_A	166_V	0.529	0.62
363_E	380_W	0.529	0.62
51_G	55_Y	0.529	0.62
322_D	325_D	0.528	0.61
454_L	457_H	0.528	0.61
395_R	399_A	0.527	0.61
185_E	195_Y	0.527	0.61
391_I	398_Y	0.526	0.61
442_F	448_E	0.526	0.61
278_D	282_V	0.526	0.61
20_A	162_K	0.526	0.61
16_A	31_M	0.525	0.61
354_K	357_T	0.525	0.61
473_Q	481_Q	0.524	0.61
367_E	370_T	0.524	0.61
443_G	485_V	0.523	0.61
110_H	113_K	0.523	0.61
52_G	319_L	0.523	0.61
358_Y	386_L	0.522	0.61
50_H	317_R	0.522	0.61
80_H	389_G	0.520	0.60
58_H	102_R	0.519	0.60
47_K	54_R	0.519	0.60
463_A	466_A	0.519	0.60
455_V	462_R	0.518	0.60
162_K	380_W	0.518	0.60
175_A	183_I	0.518	0.60
8_V	371_P	0.516	0.60
295_V	298_T	0.516	0.60
376_I	380_W	0.515	0.60
70_E	78_A	0.515	0.60
43_S	148_D	0.514	0.59
329_A	333_D	0.514	0.59
229_I	327_P	0.513	0.59
112_G	211_K	0.513	0.59
112_G	120_S	0.513	0.59
64_V	71_R	0.513	0.59
389_G	392_E	0.512	0.59
275_Y	282_V	0.512	0.59
21_D	359_R	0.512	0.59
232_S	288_E	0.512	0.59
92_R	327_P	0.511	0.59
238_R	241_T	0.511	0.59
429_L	432_A	0.511	0.59
447_Y	450_E	0.510	0.59
455_V	486_S	0.509	0.59
332_R	353_G	0.509	0.59
102_R	120_S	0.509	0.59
158_M	387_P	0.509	0.59
413_L	417_Y	0.508	0.59
444_H	476_W	0.508	0.59
438_L	452_K	0.507	0.58
233_H	319_L	0.507	0.58
337_D	351_F	0.506	0.58
242_Q	245_A	0.506	0.58
67_A	357_T	0.505	0.58
108_Y	252_D	0.504	0.58
337_D	349_S	0.504	0.58
434_T	438_L	0.504	0.58
49_I	78_A	0.504	0.58
440_E	488_W	0.504	0.58
13_I	53_L	0.503	0.58
209_W	230_K	0.503	0.58
229_I	288_E	0.503	0.58
406_Y	414_A	0.502	0.58
366_L	369_L	0.502	0.58
68_L	261_W	0.502	0.58
178_E	185_E	0.501	0.57
232_S	309_I	0.501	0.57
63_L	68_L	0.501	0.57
67_A	255_I	0.501	0.57
417_Y	450_E	0.501	0.57
81_I	355_L	0.501	0.57
451_L	467_L	0.501	0.57
57_E	64_V	0.500	0.57
261_W	267_I	0.500	0.57
175_A	347_L	0.500	0.57

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2qcuA	2	0.99	100	0.286	Contact Map
2rghA	2	0.9541	100	0.308	Contact Map
3da1A	1	0.8782	100	0.327	Contact Map
4h1bA	1	0.7026	100	0.628	Contact Map
4x9mA	1	0.7226	100	0.63	Contact Map
3dmeA	2	0.7006	100	0.637	Contact Map
3axbA	2	0.7246	100	0.649	Contact Map
1y56B	1	0.7186	100	0.651	Contact Map
1ryiA	4	0.6846	100	0.651	Contact Map
1c0pA	2	0.6467	100	0.653	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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