BGLB - ECOLI - GREMLIN Contacts

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BGLB - 6-phospho-beta-glucosidase BglB

UniProt:	P11988	Sequences: MKAFPETFLWGGATAANQVEGAWQEDGKGISTSDLQPHGVMGKMEPRILGKENIKDVAIDFYHRYPEDIALFAEMGFTCLRISIAWARIFPQGDEVEPNEAGLAFYDRLFDEMAQAGIKPLVTLSHYEMPYGLVKNYGGWANRAVIDHFEHYARTVFTRYQHKVALWLTFNEINMSLHAPFTGVGLAEESGEAEVYQAIHHQLVASARAVKACHSLLPEAKIGNMLLGGLVYPLTCQPQDMLQAMEENRRWMFFGDVQARGQYPGYMQRFFRDHNITIEMTESDAEDLKHTVDFISFSYYMTGCVSHDESINKNAQGNILNMIPNPHLKSSEWGWQIDPVGLRVLLNTLWDRYQKPLFIVENGLGAKDSVEADGSIQDDYRIAYLNDHLVQVNEAIADGVDIMGYTSWGPIDLVSASHSQMSKRYGFIYVDRDDNGEGSLTRTRKKSFGWYAEVIKTRGLSLKKITIKAP	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10114
Length:	470 (437)
Sequences:	6789 (4186)
Seq/√Len:	200.2

ECOLI - BGLB ASCB BGLA
BACSU - BGLA BGLH BGLC GMUD
SULSO - BGAL

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
26_D	101_A	4.221	1.00
377_Q	446_K	4.057	1.00
111_D	163_K	3.614	1.00
107_D	163_K	3.189	1.00
392_V	402_I	3.168	1.00
73_A	116_A	3.086	1.00
66_P	112_E	3.001	1.00
107_D	159_R	2.952	1.00
444_R	448_F	2.919	1.00
112_E	115_Q	2.892	1.00
124_L	156_V	2.889	1.00
60_D	63_H	2.839	1.00
100_E	104_A	2.823	1.00
104_A	108_R	2.789	1.00
100_E	159_R	2.736	1.00
90_F	155_T	2.719	1.00
299_Y	388_H	2.694	1.00
391_Q	394_E	2.648	1.00
154_R	158_T	2.605	1.00
235_T	240_D	2.603	1.00
25_E	63_H	2.551	1.00
12_G	77_F	2.475	1.00
385_L	407_S	2.350	1.00
343_R	398_D	2.339	1.00
347_N	398_D	2.297	1.00
383_A	387_D	2.274	1.00
70_A	116_A	2.266	1.00
213_C	222_I	2.236	1.00
38_H	56_D	2.235	1.00
147_D	208_R	2.207	1.00
143_R	284_D	2.202	1.00
429_Y	443_T	2.183	1.00
61_F	105_F	2.156	1.00
211_K	215_S	2.152	1.00
379_D	446_K	2.144	1.00
66_P	108_R	2.143	1.00
110_F	160_Y	2.123	1.00
79_C	406_T	2.070	1.00
119_K	165_A	2.041	1.00
452_A	456_K	2.033	1.00
61_F	80_L	2.011	1.00
69_I	109_L	1.981	1.00
371_E	375_S	1.967	1.00
84_I	122_V	1.964	1.00
150_E	212_A	1.914	1.00
114_A	163_K	1.909	1.00
35_L	131_Y	1.909	1.00
101_A	104_A	1.890	1.00
265_G	269_R	1.886	1.00
154_R	212_A	1.861	1.00
82_I	110_F	1.857	1.00
23_W	30_I	1.849	1.00
31_S	87_A	1.837	1.00
69_I	116_A	1.833	1.00
200_H	263_Y	1.821	1.00
343_R	394_E	1.800	1.00
283_S	286_E	1.798	1.00
154_R	216_L	1.787	1.00
232_Y	344_V	1.783	1.00
213_C	220_A	1.779	1.00
107_D	111_D	1.773	1.00
30_I	35_L	1.766	1.00
208_R	287_D	1.725	1.00
217_L	220_A	1.702	1.00
112_E	116_A	1.699	1.00
22_A	25_E	1.693	1.00
14_T	19_V	1.686	1.00
119_K	166_L	1.670	1.00
111_D	114_A	1.656	1.00
82_I	109_L	1.639	1.00
340_V	391_Q	1.635	1.00
70_A	112_E	1.633	1.00
137_Y	148_H	1.632	1.00
113_M	118_I	1.613	1.00
110_F	114_A	1.611	1.00
10_W	458_R	1.609	1.00
343_R	347_N	1.600	1.00
150_E	208_R	1.591	1.00
107_D	160_Y	1.590	1.00
348_T	352_R	1.587	1.00
280_M	285_A	1.586	1.00
299_Y	341_G	1.584	1.00
346_L	400_V	1.577	1.00
453_E	456_K	1.575	1.00
132_G	136_N	1.572	1.00
69_I	112_E	1.570	1.00
260_R	354_Q	1.566	1.00
65_Y	108_R	1.557	1.00
262_Q	289_K	1.548	1.00
9_L	79_C	1.542	1.00
358_F	403_M	1.527	1.00
17_N	55_K	1.524	1.00
145_V	148_H	1.522	1.00
79_C	121_L	1.512	1.00
168_L	225_M	1.510	1.00
141_A	194_E	1.483	1.00
431_D	439_S	1.481	1.00
157_F	213_C	1.470	1.00
39_G	43_K	1.461	1.00
64_R	67_E	1.454	1.00
199_I	254_F	1.452	1.00
162_H	217_L	1.444	1.00
253_F	267_M	1.439	1.00
103_L	155_T	1.436	1.00
14_T	80_L	1.434	1.00
69_I	113_M	1.423	1.00
255_G	295_I	1.416	1.00
248_N	266_Y	1.412	1.00
72_F	77_F	1.407	1.00
168_L	294_F	1.395	1.00
362_N	405_Y	1.394	1.00
350_W	355_K	1.393	1.00
342_L	392_V	1.390	1.00
90_F	98_P	1.380	1.00
212_A	215_S	1.380	1.00
82_I	122_V	1.375	1.00
332_E	367_K	1.371	1.00
35_L	136_N	1.363	1.00
29_G	93_G	1.361	1.00
407_S	427_F	1.361	1.00
138_G	142_N	1.356	1.00
121_L	406_T	1.353	1.00
262_Q	268_Q	1.348	1.00
74_E	448_F	1.346	1.00
453_E	457_T	1.330	1.00
346_L	392_V	1.326	1.00
60_D	64_R	1.317	1.00
22_A	63_H	1.314	1.00
166_L	221_K	1.309	1.00
92_Q	95_E	1.308	1.00
224_N	258_Q	1.305	1.00
165_A	219_E	1.303	1.00
84_I	156_V	1.296	1.00
450_W	454_V	1.280	1.00
131_Y	135_K	1.273	1.00
444_R	449_G	1.270	1.00
262_Q	354_Q	1.263	1.00
84_I	89_I	1.243	1.00
389_L	392_V	1.240	1.00
449_G	452_A	1.234	1.00
189_E	194_E	1.230	1.00
387_D	390_V	1.227	1.00
170_F	202_Q	1.224	1.00
94_D	148_H	1.224	1.00
147_D	150_E	1.219	1.00
170_F	205_A	1.215	1.00
144_A	147_D	1.213	1.00
191_G	194_E	1.210	1.00
386_N	390_V	1.204	1.00
281_T	284_D	1.202	1.00
347_N	400_V	1.202	1.00
103_L	159_R	1.199	1.00
72_F	428_I	1.197	1.00
176_S	202_Q	1.193	1.00
70_A	74_E	1.190	1.00
107_D	162_H	1.169	1.00
143_R	201_H	1.169	1.00
157_F	209_A	1.167	1.00
61_F	109_L	1.166	1.00
393_N	397_A	1.165	1.00
371_E	377_Q	1.161	1.00
94_D	137_Y	1.160	1.00
140_W	145_V	1.160	1.00
131_Y	136_N	1.156	1.00
221_K	356_P	1.155	1.00
285_A	288_L	1.151	1.00
350_W	401_D	1.150	1.00
59_I	411_I	1.148	1.00
23_W	28_K	1.142	1.00
65_Y	112_E	1.134	1.00
129_M	145_V	1.131	1.00
375_S	446_K	1.127	1.00
5_P	396_I	1.125	1.00
14_T	82_I	1.120	1.00
256_D	352_R	1.119	1.00
158_T	216_L	1.115	1.00
432_R	440_L	1.115	1.00
233_P	244_A	1.111	1.00
157_F	222_I	1.111	1.00
124_L	149_F	1.110	1.00
256_D	260_R	1.110	1.00
29_G	132_G	1.107	1.00
238_P	242_L	1.094	1.00
153_A	209_A	1.092	1.00
150_E	209_A	1.087	1.00
103_L	107_D	1.078	1.00
210_V	214_H	1.073	1.00
374_G	443_T	1.073	1.00
233_P	241_M	1.070	1.00
394_E	397_A	1.070	1.00
393_N	396_I	1.068	1.00
92_Q	132_G	1.068	1.00
150_E	154_R	1.067	1.00
248_N	267_M	1.066	1.00
451_Y	455_I	1.063	1.00
110_F	163_K	1.061	1.00
213_C	217_L	1.060	1.00
239_Q	340_V	1.060	1.00
340_V	344_V	1.059	1.00
144_A	148_H	1.059	1.00
137_Y	144_A	1.058	1.00
238_P	241_M	1.058	1.00
213_C	218_P	1.057	1.00
231_V	247_E	1.056	1.00
228_G	345_L	1.054	1.00
74_E	444_R	1.053	1.00
4_F	396_I	1.051	1.00
234_L	306_S	1.050	1.00
98_P	155_T	1.049	1.00
242_L	246_E	1.045	1.00
12_G	72_F	1.045	1.00
110_F	122_V	1.045	1.00
107_D	114_A	1.044	1.00
208_R	212_A	1.044	1.00
201_H	204_V	1.042	1.00
383_A	386_N	1.041	1.00
92_Q	97_E	1.041	1.00
370_V	443_T	1.036	1.00
4_F	393_N	1.032	1.00
212_A	216_L	1.027	1.00
248_N	252_M	1.025	1.00
22_A	26_D	1.022	1.00
431_D	441_T	1.020	1.00
57_V	432_R	1.016	1.00
29_G	91_P	1.015	1.00
330_S	336_Q	1.011	1.00
282_E	285_A	1.010	1.00
239_Q	307_H	1.010	1.00
331_S	364_L	1.007	1.00
324_P	328_L	1.007	1.00
153_A	212_A	1.004	1.00
64_R	441_T	1.002	1.00
240_D	307_H	0.997	1.00
57_V	440_L	0.995	1.00
262_Q	265_G	0.995	1.00
342_L	359_I	0.995	1.00
155_T	159_R	0.994	1.00
342_L	402_I	0.994	1.00
148_H	151_H	0.991	1.00
161_Q	220_A	0.991	1.00
333_W	365_G	0.988	1.00
121_L	358_F	0.981	1.00
237_Q	241_M	0.981	1.00
211_K	290_H	0.973	0.99
329_K	387_D	0.968	0.99
382_I	450_W	0.965	0.99
121_L	166_L	0.964	0.99
89_I	155_T	0.963	0.99
269_R	272_R	0.962	0.99
154_R	217_L	0.960	0.99
367_K	422_S	0.960	0.99
129_M	139_G	0.959	0.99
146_I	208_R	0.959	0.99
242_L	245_M	0.958	0.99
329_K	380_Y	0.953	0.99
9_L	121_L	0.952	0.99
7_T	403_M	0.951	0.99
19_V	61_F	0.948	0.99
223_G	296_S	0.940	0.99
247_E	305_V	0.940	0.99
424_R	432_R	0.939	0.99
241_M	244_A	0.937	0.99
245_M	248_N	0.936	0.99
156_V	160_Y	0.936	0.99
324_P	330_S	0.935	0.99
143_R	281_T	0.934	0.99
210_V	222_I	0.929	0.99
157_F	220_A	0.925	0.99
366_A	380_Y	0.921	0.99
411_I	430_V	0.920	0.99
138_G	141_A	0.917	0.99
28_K	87_A	0.917	0.99
53_N	422_S	0.915	0.99
192_E	274_H	0.911	0.99
370_V	374_G	0.907	0.99
104_A	107_D	0.907	0.99
177_L	198_A	0.905	0.99
95_E	132_G	0.898	0.99
67_E	70_A	0.897	0.99
153_A	157_F	0.896	0.99
108_R	111_D	0.895	0.99
333_W	423_K	0.892	0.99
259_A	355_K	0.890	0.99
27_G	99_N	0.884	0.99
137_Y	145_V	0.884	0.99
231_V	244_A	0.880	0.99
364_L	380_Y	0.880	0.99
152_Y	156_V	0.879	0.99
236_C	241_M	0.879	0.99
350_W	354_Q	0.877	0.99
70_A	73_A	0.870	0.99
365_G	423_K	0.870	0.99
162_H	220_A	0.869	0.99
223_G	294_F	0.868	0.99
78_T	458_R	0.867	0.99
270_F	274_H	0.864	0.99
209_A	212_A	0.857	0.99
211_K	287_D	0.856	0.99
103_L	156_V	0.855	0.99
245_M	266_Y	0.855	0.99
159_R	163_K	0.854	0.99
105_F	109_L	0.852	0.99
77_F	410_P	0.852	0.99
125_S	129_M	0.850	0.99
107_D	110_F	0.849	0.99
396_I	402_I	0.847	0.99
3_A	6_E	0.844	0.99
226_L	255_G	0.844	0.99
324_P	327_H	0.844	0.99
161_Q	217_L	0.842	0.99
449_G	453_E	0.841	0.99
114_A	120_P	0.841	0.99
342_L	391_Q	0.838	0.98
390_V	394_E	0.838	0.98
283_S	287_D	0.837	0.98
193_A	278_I	0.834	0.98
371_E	374_G	0.829	0.98
340_V	394_E	0.827	0.98
297_F	357_L	0.826	0.98
168_L	296_S	0.825	0.98
256_D	353_Y	0.824	0.98
329_K	383_A	0.821	0.98
94_D	136_N	0.820	0.98
376_I	443_T	0.816	0.98
72_F	118_I	0.815	0.98
206_S	210_V	0.814	0.98
379_D	383_A	0.813	0.98
370_V	375_S	0.812	0.98
302_T	336_Q	0.811	0.98
347_N	351_D	0.810	0.98
301_M	336_Q	0.810	0.98
74_E	452_A	0.809	0.98
228_G	297_F	0.808	0.98
338_D	341_G	0.807	0.98
170_F	176_S	0.806	0.98
208_R	211_K	0.806	0.98
10_W	389_L	0.804	0.98
94_D	132_G	0.804	0.98
259_A	292_V	0.803	0.98
146_I	204_V	0.801	0.98
141_A	189_E	0.800	0.98
302_T	338_D	0.798	0.98
19_V	59_I	0.796	0.98
32_T	129_M	0.796	0.98
16_A	85_A	0.795	0.98
269_R	273_D	0.794	0.98
93_G	132_G	0.793	0.98
169_T	224_N	0.789	0.98
343_R	391_Q	0.787	0.98
125_S	128_E	0.786	0.98
77_F	451_Y	0.785	0.98
142_N	148_H	0.781	0.98
252_M	352_R	0.778	0.98
234_L	240_D	0.778	0.98
89_I	156_V	0.777	0.98
193_A	197_Q	0.777	0.98
454_V	459_G	0.777	0.98
197_Q	279_E	0.776	0.98
175_M	227_L	0.776	0.98
181_F	187_A	0.774	0.97
9_L	119_K	0.774	0.97
5_P	401_D	0.771	0.97
65_Y	69_I	0.771	0.97
446_K	449_G	0.771	0.97
302_T	341_G	0.768	0.97
28_K	31_S	0.765	0.97
231_V	305_V	0.758	0.97
75_M	444_R	0.758	0.97
57_V	60_D	0.757	0.97
169_T	206_S	0.757	0.97
306_S	321_N	0.757	0.97
135_K	181_F	0.753	0.97
265_G	268_Q	0.752	0.97
350_W	400_V	0.746	0.97
100_E	107_D	0.742	0.97
347_N	350_W	0.741	0.97
259_A	295_I	0.741	0.97
98_P	103_L	0.740	0.97
155_T	158_T	0.740	0.97
149_F	153_A	0.739	0.97
73_A	117_G	0.739	0.97
199_I	253_F	0.738	0.97
428_I	444_R	0.738	0.97
68_D	442_R	0.737	0.97
337_I	366_A	0.737	0.97
413_L	425_Y	0.736	0.97
245_M	348_T	0.733	0.96
90_F	95_E	0.733	0.96
102_G	105_F	0.732	0.96
346_L	402_I	0.730	0.96
122_V	164_V	0.729	0.96
85_A	128_E	0.728	0.96
161_Q	216_L	0.727	0.96
24_Q	30_I	0.725	0.96
355_K	401_D	0.724	0.96
241_M	245_M	0.722	0.96
94_D	151_H	0.721	0.96
242_L	340_V	0.718	0.96
169_T	222_I	0.718	0.96
332_E	366_A	0.718	0.96
141_A	198_A	0.717	0.96
175_M	179_A	0.714	0.96
395_A	400_V	0.714	0.96
237_Q	240_D	0.714	0.96
26_D	62_Y	0.712	0.96
14_T	411_I	0.711	0.96
325_N	328_L	0.709	0.96
120_P	165_A	0.709	0.96
174_N	227_L	0.708	0.96
454_V	458_R	0.707	0.96
357_L	400_V	0.707	0.96
203_L	258_Q	0.703	0.96
203_L	288_L	0.701	0.95
23_W	56_D	0.698	0.95
157_F	216_L	0.698	0.95
225_M	298_S	0.696	0.95
64_R	440_L	0.695	0.95
179_A	184_V	0.695	0.95
147_D	151_H	0.694	0.95
389_L	407_S	0.692	0.95
340_V	343_R	0.691	0.95
3_A	393_N	0.691	0.95
90_F	97_E	0.690	0.95
92_Q	136_N	0.688	0.95
230_L	344_V	0.687	0.95
114_A	165_A	0.687	0.95
30_I	38_H	0.686	0.95
267_M	271_F	0.686	0.95
7_T	458_R	0.682	0.95
55_K	58_A	0.679	0.95
382_I	446_K	0.678	0.95
143_R	204_V	0.678	0.95
23_W	85_A	0.677	0.95
19_V	413_L	0.675	0.94
415_S	425_Y	0.675	0.94
113_M	117_G	0.675	0.94
149_F	170_F	0.673	0.94
205_A	209_A	0.673	0.94
261_G	289_K	0.672	0.94
22_A	62_Y	0.672	0.94
10_W	78_T	0.670	0.94
114_A	119_K	0.670	0.94
228_G	255_G	0.666	0.94
389_L	454_V	0.663	0.94
427_F	451_Y	0.663	0.94
75_M	427_F	0.660	0.94
226_L	254_F	0.659	0.94
298_S	360_V	0.659	0.94
262_Q	285_A	0.656	0.94
232_Y	302_T	0.656	0.94
237_Q	307_H	0.656	0.94
201_H	281_T	0.653	0.93
371_E	443_T	0.651	0.93
90_F	94_D	0.650	0.93
82_I	113_M	0.649	0.93
272_R	277_T	0.649	0.93
154_R	215_S	0.648	0.93
44_M	53_N	0.648	0.93
207_A	288_L	0.647	0.93
356_P	401_D	0.647	0.93
156_V	167_W	0.646	0.93
295_I	355_K	0.646	0.93
164_V	167_W	0.644	0.93
193_A	277_T	0.644	0.93
110_F	164_V	0.644	0.93
158_T	212_A	0.644	0.93
13_A	406_T	0.644	0.93
143_R	283_S	0.643	0.93
374_G	441_T	0.641	0.93
299_Y	342_L	0.640	0.93
356_P	403_M	0.638	0.93
371_E	376_I	0.637	0.93
375_S	443_T	0.637	0.93
78_T	119_K	0.637	0.93
121_L	168_L	0.635	0.92
346_L	395_A	0.634	0.92
282_E	286_E	0.633	0.92
243_Q	247_E	0.632	0.92
153_A	156_V	0.632	0.92
113_M	116_A	0.632	0.92
11_G	406_T	0.631	0.92
9_L	78_T	0.631	0.92
95_E	151_H	0.631	0.92
297_F	349_L	0.631	0.92
285_A	289_K	0.630	0.92
333_W	418_H	0.629	0.92
308_D	311_I	0.629	0.92
72_F	410_P	0.627	0.92
211_K	291_T	0.624	0.92
221_K	403_M	0.624	0.92
429_Y	445_K	0.623	0.92
190_S	193_A	0.621	0.92
66_P	70_A	0.621	0.92
200_H	280_M	0.620	0.92
358_F	404_G	0.619	0.92
196_Y	271_F	0.619	0.92
394_E	398_D	0.616	0.91
392_V	396_I	0.616	0.91
370_V	373_D	0.616	0.91
133_L	148_H	0.616	0.91
180_P	187_A	0.616	0.91
375_S	449_G	0.616	0.91
42_G	52_E	0.615	0.91
269_R	394_E	0.615	0.91
125_S	176_S	0.615	0.91
114_A	117_G	0.615	0.91
228_G	251_W	0.614	0.91
55_K	419_S	0.613	0.91
141_A	197_Q	0.612	0.91
30_I	131_Y	0.610	0.91
81_R	171_N	0.610	0.91
248_N	348_T	0.609	0.91
414_V	432_R	0.608	0.91
151_H	155_T	0.606	0.91
90_F	151_H	0.605	0.91
69_I	118_I	0.604	0.91
135_K	189_E	0.604	0.91
429_Y	441_T	0.603	0.90
146_I	205_A	0.602	0.90
332_E	423_K	0.602	0.90
197_Q	201_H	0.601	0.90
440_L	444_R	0.600	0.90
84_I	110_F	0.599	0.90
216_L	220_A	0.599	0.90
267_M	270_F	0.599	0.90
234_L	304_C	0.599	0.90
71_L	428_I	0.598	0.90
379_D	382_I	0.598	0.90
255_G	349_L	0.598	0.90
330_S	334_G	0.598	0.90
281_T	285_A	0.596	0.90
410_P	428_I	0.596	0.90
103_L	160_Y	0.596	0.90
14_T	410_P	0.596	0.90
124_L	157_F	0.596	0.90
287_D	290_H	0.596	0.90
19_V	80_L	0.595	0.90
252_M	348_T	0.595	0.90
71_L	411_I	0.594	0.90
207_A	291_T	0.594	0.90
228_G	349_L	0.593	0.90
51_K	422_S	0.592	0.90
39_G	42_G	0.591	0.90
235_T	306_S	0.589	0.89
207_A	290_H	0.586	0.89
37_P	414_V	0.586	0.89
89_I	103_L	0.585	0.89
58_A	440_L	0.584	0.89
413_L	416_A	0.583	0.89
253_F	271_F	0.583	0.89
75_M	448_F	0.580	0.89
7_T	396_I	0.580	0.89
211_K	214_H	0.579	0.89
30_I	87_A	0.579	0.89
454_V	457_T	0.578	0.89
66_P	69_I	0.578	0.89
93_G	133_L	0.575	0.88
223_G	358_F	0.575	0.88
124_L	153_A	0.574	0.88
181_F	189_E	0.573	0.88
358_F	406_T	0.572	0.88
300_Y	361_E	0.572	0.88
4_F	458_R	0.571	0.88
210_V	292_V	0.570	0.88
32_T	135_K	0.569	0.88
357_L	402_I	0.569	0.88
80_L	113_M	0.568	0.88
111_D	162_H	0.566	0.87
328_L	336_Q	0.565	0.87
76_G	452_A	0.564	0.87
146_I	150_E	0.564	0.87
61_F	72_F	0.563	0.87
166_L	358_F	0.563	0.87
184_V	418_H	0.563	0.87
360_V	403_M	0.562	0.87
36_Q	188_E	0.562	0.87
108_R	112_E	0.560	0.87
206_S	258_Q	0.560	0.87
92_Q	148_H	0.559	0.87
73_A	115_Q	0.559	0.87
252_M	256_D	0.558	0.87
161_Q	218_P	0.557	0.87
323_I	327_H	0.557	0.87
247_E	250_R	0.556	0.87
64_R	439_S	0.553	0.86
22_A	28_K	0.552	0.86
232_Y	338_D	0.551	0.86
306_S	323_I	0.551	0.86
78_T	455_I	0.551	0.86
229_G	303_G	0.545	0.85
331_S	366_A	0.544	0.85
57_V	63_H	0.544	0.85
414_V	421_M	0.543	0.85
185_G	188_E	0.542	0.85
37_P	55_K	0.542	0.85
43_K	188_E	0.541	0.85
132_G	148_H	0.541	0.85
246_E	307_H	0.541	0.85
32_T	125_S	0.540	0.85
61_F	65_Y	0.540	0.85
409_G	413_L	0.540	0.85
210_V	290_H	0.539	0.85
172_E	300_Y	0.537	0.85
349_L	357_L	0.536	0.85
111_D	115_Q	0.536	0.85
78_T	459_G	0.535	0.84
137_Y	142_N	0.535	0.84
344_V	347_N	0.534	0.84
4_F	10_W	0.534	0.84
72_F	80_L	0.533	0.84
190_S	195_V	0.532	0.84
121_L	403_M	0.532	0.84
23_W	38_H	0.530	0.84
132_G	135_K	0.530	0.84
140_W	170_F	0.529	0.84
382_I	386_N	0.528	0.84
296_S	360_V	0.527	0.84
77_F	118_I	0.526	0.83
133_L	145_V	0.526	0.83
204_V	287_D	0.525	0.83
74_E	449_G	0.524	0.83
14_T	61_F	0.524	0.83
14_T	413_L	0.523	0.83
29_G	90_F	0.522	0.83
7_T	78_T	0.521	0.83
376_I	429_Y	0.521	0.83
249_R	267_M	0.521	0.83
225_M	294_F	0.521	0.83
196_Y	274_H	0.519	0.83
255_G	259_A	0.519	0.83
331_S	334_G	0.518	0.82
385_L	389_L	0.518	0.82
331_S	365_G	0.517	0.82
280_M	283_S	0.516	0.82
210_V	213_C	0.515	0.82
204_V	288_L	0.513	0.82
132_G	137_Y	0.511	0.82
433_D	441_T	0.511	0.82
346_L	357_L	0.511	0.82
41_M	44_M	0.511	0.82
424_R	429_Y	0.508	0.81
33_S	416_A	0.508	0.81
35_L	39_G	0.508	0.81
44_M	51_K	0.507	0.81
385_L	451_Y	0.505	0.81
256_D	262_Q	0.504	0.81
201_H	279_E	0.504	0.81
408_W	413_L	0.503	0.81
61_F	69_I	0.502	0.81
315_A	318_N	0.502	0.81
418_H	423_K	0.502	0.81
36_Q	186_L	0.501	0.80
181_F	186_L	0.501	0.80
186_L	189_E	0.501	0.80
169_T	209_A	0.500	0.80
428_I	448_F	0.500	0.80

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1v02A	2	0.9447	100	0.116	Contact Map
2dgaA	5	0.9511	100	0.122	Contact Map
3ptmA	1	0.9468	100	0.123	Contact Map
1v08A	2	0.9468	100	0.124	Contact Map
2jf7A	5	0.934	100	0.124	Contact Map
3wq5A	1	0.9447	100	0.125	Contact Map
3w53A	1	0.9447	100	0.125	Contact Map
1cbgA	2	0.9468	100	0.128	Contact Map
4f66A	2	0.9723	100	0.129	Contact Map
4iplA	2	0.9617	100	0.129	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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