SYR - ECOLI - GREMLIN Contacts

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SYR - Arginine--tRNA ligase

UniProt:	P11875	Sequences: MNIQALLSEKVRQAMIAAGAPADCEPQVRQSAKVQFGDYQANGMMAVAKKLGMAPRQLAEQVLTHLDLNGIASKVEIAGPGFINIFLDPAFLAEHVQQALASDRLGVATPEKQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVGDWGTQFGMLIAWLEKQQQENAGEMELADLEGFYRDAKKHYDEDEEFAERARNYVVKLQSGDEYFREMWRKLVDITMTQNQITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGEPMGVIIQKKDGGYLYTTTDIACAKYRYETLHADRVLYYIDSRQHQHLMQAWAIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALERARRLVAEKNPDMPADELEKLANAVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKAEIDEEQLAAAPVIIREDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDLAGLFSGFYEHCPILSAENEEVRNSRLKLAQLTAKTLKLGLDTLGIETVERM	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10071
Length:	577 (557)
Sequences:	2678 (1754)
Seq/√Len:	74.3

ECOLI - SYR
BACSU - SYR
HALSA - SYR
SULSO - SYR

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
114_T	152_K	5.719	1.00
523_L	565_G	5.504	1.00
270_A	274_A	4.866	1.00
60_E	64_T	4.006	1.00
245_R	422_N	3.954	1.00
216_K	221_D	3.943	1.00
175_K	209_R	3.823	1.00
245_R	395_D	3.801	1.00
53_M	61_Q	3.600	1.00
273_K	285_T	3.491	1.00
145_T	568_T	3.442	1.00
402_R	418_E	3.436	1.00
271_D	275_K	3.407	1.00
54_A	57_Q	3.182	1.00
215_V	219_S	2.946	1.00
337_I	345_L	2.851	1.00
74_K	86_F	2.845	1.00
147_E	155_R	2.840	1.00
240_Q	244_D	2.824	1.00
394_L	429_V	2.783	1.00
212_N	216_K	2.704	1.00
63_L	83_I	2.668	1.00
406_A	417_L	2.662	1.00
538_P	541_S	2.588	1.00
375_K	445_D	2.553	1.00
464_Y	573_T	2.504	1.00
350_A	353_R	2.495	1.00
467_V	555_A	2.489	1.00
143_V	155_R	2.458	1.00
279_V	288_F	2.453	1.00
353_R	362_V	2.437	1.00
135_S	369_F	2.427	1.00
174_E	223_Y	2.402	1.00
321_A	352_V	2.374	1.00
195_D	198_K	2.320	1.00
195_D	199_H	2.304	1.00
419_K	423_A	2.296	1.00
270_A	273_K	2.296	1.00
402_R	406_A	2.284	1.00
499_R	529_L	2.241	1.00
213_Y	224_F	2.234	1.00
420_L	424_V	2.224	1.00
503_F	564_L	2.207	1.00
141_A	144_R	2.180	1.00
117_V	142_A	2.161	1.00
113_Q	332_R	2.157	1.00
222_E	226_E	2.147	1.00
113_Q	331_D	2.135	1.00
464_Y	468_L	2.132	1.00
400_R	403_R	2.129	1.00
539_I	555_A	2.124	1.00
247_N	572_E	2.111	1.00
349_W	364_L	2.111	1.00
267_G	326_E	2.074	1.00
149_L	511_A	2.074	1.00
89_P	494_A	2.053	1.00
423_A	572_E	2.022	1.00
416_E	419_K	2.012	1.00
73_S	88_D	1.975	1.00
266_P	270_A	1.956	1.00
199_H	202_E	1.937	1.00
522_Y	526_L	1.937	1.00
56_R	79_G	1.929	1.00
365_E	514_G	1.926	1.00
208_E	212_N	1.916	1.00
464_Y	563_K	1.895	1.00
507_L	568_T	1.883	1.00
16_I	22_A	1.865	1.00
229_R	233_D	1.862	1.00
332_R	365_E	1.849	1.00
99_A	500_L	1.848	1.00
396_E	400_R	1.848	1.00
446_W	450_L	1.827	1.00
302_V	314_T	1.814	1.00
510_V	519_M	1.813	1.00
431_Y	455_N	1.807	1.00
422_N	572_E	1.797	1.00
464_Y	559_A	1.796	1.00
273_K	305_Q	1.786	1.00
400_R	447_D	1.784	1.00
530_F	555_A	1.784	1.00
472_R	575_E	1.749	1.00
287_V	351_I	1.743	1.00
114_T	154_I	1.732	1.00
120_S	136_T	1.729	1.00
499_R	502_Q	1.727	1.00
120_S	243_Y	1.725	1.00
468_L	559_A	1.705	1.00
148_F	564_L	1.703	1.00
427_G	461_Q	1.702	1.00
398_L	422_N	1.690	1.00
340_R	371_M	1.680	1.00
140_D	144_R	1.670	1.00
291_E	354_K	1.651	1.00
104_R	107_V	1.633	1.00
271_D	357_Y	1.633	1.00
278_A	285_T	1.632	1.00
233_D	237_T	1.627	1.00
323_Y	327_T	1.617	1.00
560_K	564_L	1.605	0.99
245_R	398_L	1.601	0.99
175_K	199_H	1.599	0.99
198_K	202_E	1.598	0.99
222_E	229_R	1.591	0.99
419_K	422_N	1.577	0.99
268_I	322_K	1.570	0.99
280_E	285_T	1.569	0.99
494_A	498_A	1.560	0.99
373_L	441_D	1.541	0.99
225_R	229_R	1.536	0.99
413_P	416_E	1.527	0.99
564_L	567_D	1.517	0.99
57_Q	61_Q	1.516	0.99
176_Q	199_H	1.514	0.99
398_L	418_E	1.506	0.99
89_P	491_D	1.502	0.99
312_L	315_T	1.502	0.99
148_F	503_F	1.501	0.99
115_I	151_H	1.497	0.99
254_D	328_L	1.483	0.99
212_N	215_V	1.481	0.99
146_L	514_G	1.479	0.99
61_Q	64_T	1.475	0.99
502_Q	505_E	1.468	0.99
39_Y	87_L	1.466	0.99
556_Q	560_K	1.453	0.99
523_L	562_L	1.449	0.99
474_A	552_L	1.447	0.99
496_L	558_T	1.430	0.99
271_D	274_A	1.421	0.99
146_L	511_A	1.421	0.99
267_G	270_A	1.412	0.99
28_V	39_Y	1.410	0.99
500_L	561_T	1.409	0.99
142_A	367_H	1.406	0.99
56_R	60_E	1.405	0.99
490_E	493_E	1.404	0.99
468_L	575_E	1.401	0.99
32_A	36_F	1.399	0.99
431_Y	524_Y	1.393	0.98
221_D	224_F	1.392	0.98
399_E	403_R	1.386	0.98
545_E	548_R	1.378	0.98
272_L	355_A	1.374	0.98
149_L	507_L	1.370	0.98
119_Y	155_R	1.363	0.98
9_E	13_Q	1.358	0.98
171_A	213_Y	1.354	0.98
334_L	367_H	1.350	0.98
467_V	530_F	1.348	0.98
145_T	510_V	1.347	0.98
395_D	399_E	1.343	0.98
302_V	348_A	1.342	0.98
509_V	513_E	1.341	0.98
463_A	531_S	1.338	0.98
235_T	239_N	1.337	0.98
271_D	322_K	1.334	0.98
76_E	86_F	1.330	0.98
470_V	539_I	1.330	0.98
171_A	210_A	1.329	0.98
292_F	354_K	1.322	0.98
260_L	323_Y	1.319	0.98
519_M	565_G	1.317	0.98
540_L	548_R	1.316	0.98
119_Y	143_V	1.315	0.98
112_K	151_H	1.314	0.98
487_I	547_V	1.307	0.98
245_R	394_L	1.288	0.97
242_T	391_A	1.281	0.97
267_G	271_D	1.271	0.97
140_D	430_K	1.268	0.97
303_I	314_T	1.266	0.97
524_Y	528_G	1.265	0.97
13_Q	17_A	1.265	0.97
62_V	83_I	1.262	0.97
302_V	351_I	1.261	0.97
488_I	550_S	1.259	0.97
458_P	577_M	1.253	0.97
144_R	567_D	1.250	0.97
172_W	192_F	1.249	0.97
334_L	514_G	1.246	0.97
14_A	18_A	1.243	0.97
116_V	330_A	1.240	0.97
398_L	402_R	1.240	0.97
428_A	458_P	1.239	0.97
191_G	195_D	1.233	0.97
423_A	574_V	1.232	0.97
350_A	354_K	1.231	0.97
339_S	368_M	1.229	0.97
73_S	89_P	1.229	0.97
196_A	206_F	1.228	0.97
546_E	549_N	1.225	0.97
404_L	407_E	1.223	0.97
184_M	187_A	1.221	0.97
285_T	305_Q	1.215	0.96
117_V	153_V	1.206	0.96
53_M	57_Q	1.205	0.96
462_Y	531_S	1.204	0.96
156_A	320_C	1.200	0.96
63_L	77_I	1.198	0.96
414_A	418_E	1.198	0.96
190_E	387_T	1.191	0.96
140_D	570_G	1.185	0.96
566_L	571_I	1.184	0.96
268_I	319_A	1.179	0.96
402_R	421_A	1.173	0.96
321_A	335_Y	1.170	0.96
499_R	525_D	1.169	0.96
322_K	326_E	1.160	0.95
145_T	511_A	1.160	0.95
526_L	558_T	1.159	0.95
56_R	77_I	1.158	0.95
236_M	255_V	1.156	0.95
545_E	549_N	1.156	0.95
533_F	537_C	1.154	0.95
314_T	348_A	1.150	0.95
541_S	548_R	1.149	0.95
177_Q	180_N	1.148	0.95
130_V	393_L	1.148	0.95
314_T	351_I	1.142	0.95
273_K	280_E	1.135	0.95
117_V	143_V	1.133	0.95
338_D	342_H	1.131	0.95
269_V	304_I	1.129	0.95
398_L	426_I	1.123	0.94
542_A	547_V	1.122	0.94
358_V	364_L	1.120	0.94
68_L	72_A	1.115	0.94
273_K	278_A	1.114	0.94
172_W	175_K	1.114	0.94
493_E	551_R	1.105	0.94
199_H	203_D	1.105	0.94
51_L	58_L	1.104	0.94
477_D	480_Q	1.098	0.94
343_Q	347_Q	1.097	0.94
234_I	237_T	1.096	0.94
53_M	58_L	1.092	0.94
172_W	196_A	1.089	0.93
238_Q	241_I	1.082	0.93
97_Q	100_L	1.076	0.93
403_R	406_A	1.074	0.93
17_A	65_H	1.073	0.93
500_L	526_L	1.073	0.93
336_Y	367_H	1.072	0.93
168_M	196_A	1.068	0.93
75_V	85_I	1.068	0.93
201_D	384_A	1.066	0.93
491_D	495_Q	1.063	0.93
38_D	498_A	1.063	0.93
12_R	16_I	1.062	0.93
147_E	249_T	1.061	0.93
180_N	183_E	1.059	0.92
281_S	286_V	1.054	0.92
188_D	192_F	1.052	0.92
44_M	62_V	1.051	0.92
452_F	458_P	1.050	0.92
321_A	360_E	1.046	0.92
332_R	363_P	1.045	0.92
144_R	147_E	1.043	0.92
492_R	536_H	1.043	0.92
537_C	551_R	1.042	0.92
107_V	148_F	1.041	0.92
530_F	534_Y	1.031	0.91
330_A	333_V	1.029	0.91
47_V	58_L	1.029	0.91
334_L	365_E	1.029	0.91
188_D	191_G	1.025	0.91
538_P	542_A	1.018	0.91
338_D	371_M	1.013	0.91
419_K	572_E	1.013	0.91
342_H	346_M	1.013	0.91
398_L	425_G	1.011	0.91
33_K	36_F	1.009	0.91
269_V	273_K	1.009	0.91
472_R	576_R	1.006	0.90
405_V	409_N	1.005	0.90
38_D	494_A	1.005	0.90
147_E	153_V	1.005	0.90
244_D	249_T	1.004	0.90
435_S	448_N	1.003	0.90
120_S	157_N	1.002	0.90
94_E	97_Q	0.999	0.90
403_R	407_E	0.998	0.90
324_R	335_Y	0.998	0.90
397_A	400_R	0.997	0.90
66_L	75_V	0.995	0.90
566_L	573_T	0.991	0.90
56_R	78_A	0.990	0.90
490_E	537_C	0.984	0.89
318_I	352_V	0.981	0.89
129_H	372_M	0.979	0.89
503_F	507_L	0.978	0.89
396_E	446_W	0.978	0.89
342_H	368_M	0.978	0.89
171_A	175_K	0.976	0.89
300_M	343_Q	0.972	0.89
116_V	333_V	0.971	0.89
423_A	427_G	0.968	0.89
424_V	458_P	0.967	0.89
133_L	433_D	0.967	0.89
213_Y	216_K	0.967	0.89
556_Q	559_A	0.966	0.89
465_T	468_L	0.966	0.89
268_I	318_I	0.965	0.89
414_A	417_L	0.962	0.88
499_R	526_L	0.961	0.88
337_I	368_M	0.959	0.88
99_A	557_L	0.958	0.88
197_K	201_D	0.954	0.88
142_A	336_Y	0.954	0.88
72_A	75_V	0.952	0.88
10_K	13_Q	0.947	0.88
470_V	555_A	0.946	0.88
250_L	253_D	0.941	0.87
503_F	565_G	0.933	0.87
464_Y	575_E	0.929	0.87
324_R	333_V	0.928	0.86
489_R	550_S	0.918	0.86
134_R	433_D	0.915	0.86
308_D	312_L	0.914	0.86
57_Q	60_E	0.914	0.86
158_H	261_Y	0.908	0.85
88_D	91_F	0.907	0.85
8_S	12_R	0.904	0.85
10_K	17_A	0.902	0.85
172_W	176_Q	0.901	0.85
95_H	98_Q	0.898	0.85
543_E	547_V	0.897	0.85
405_V	410_P	0.897	0.85
178_Q	230_K	0.896	0.85
311_Y	316_T	0.895	0.84
503_F	561_T	0.895	0.84
291_E	350_A	0.895	0.84
265_L	269_V	0.894	0.84
559_A	563_K	0.893	0.84
403_R	447_D	0.890	0.84
218_Q	316_T	0.890	0.84
265_L	316_T	0.889	0.84
475_E	478_E	0.888	0.84
421_A	425_G	0.887	0.84
67_D	74_K	0.886	0.84
271_D	355_A	0.885	0.84
8_S	11_V	0.883	0.84
220_G	225_R	0.883	0.84
425_G	429_V	0.882	0.84
173_L	231_L	0.876	0.83
11_V	41_A	0.874	0.83
164_T	306_K	0.873	0.83
396_E	399_E	0.873	0.83
87_L	92_L	0.870	0.83
11_V	62_V	0.870	0.83
59_A	77_I	0.869	0.83
204_E	207_A	0.866	0.82
469_S	472_R	0.866	0.82
178_Q	182_G	0.866	0.82
15_M	20_A	0.866	0.82
34_V	37_G	0.864	0.82
271_D	326_E	0.864	0.82
303_I	312_L	0.857	0.82
325_Y	329_H	0.856	0.82
205_E	208_E	0.856	0.82
30_Q	502_Q	0.856	0.82
227_M	231_L	0.854	0.82
508_T	512_R	0.853	0.81
240_Q	255_V	0.849	0.81
322_K	357_Y	0.847	0.81
122_P	228_W	0.844	0.81
335_Y	349_W	0.844	0.81
179_E	183_E	0.842	0.81
335_Y	344_H	0.842	0.81
265_L	272_L	0.840	0.80
159_V	255_V	0.836	0.80
496_L	526_L	0.835	0.80
165_Q	382_T	0.835	0.80
493_E	554_L	0.834	0.80
325_Y	362_V	0.834	0.80
41_A	44_M	0.834	0.80
468_L	472_R	0.832	0.80
199_H	206_F	0.830	0.80
368_M	439_T	0.829	0.80
44_M	59_A	0.825	0.79
122_P	157_N	0.825	0.79
557_L	560_K	0.824	0.79
179_E	182_G	0.824	0.79
151_H	332_R	0.824	0.79
462_Y	534_Y	0.822	0.79
467_V	559_A	0.818	0.79
91_F	94_E	0.816	0.79
100_L	556_Q	0.816	0.79
168_M	197_K	0.815	0.78
223_Y	226_E	0.814	0.78
61_Q	65_H	0.812	0.78
72_A	85_I	0.811	0.78
397_A	429_V	0.808	0.78
133_L	137_I	0.808	0.78
326_E	329_H	0.807	0.78
500_L	558_T	0.806	0.78
281_S	284_A	0.805	0.78
282_E	307_K	0.801	0.77
493_E	537_C	0.798	0.77
437_N	440_T	0.797	0.77
181_A	230_K	0.797	0.77
506_T	509_V	0.793	0.77
117_V	336_Y	0.791	0.76
256_M	259_S	0.791	0.76
464_Y	574_V	0.791	0.76
100_L	553_K	0.790	0.76
180_N	191_G	0.789	0.76
113_Q	151_H	0.788	0.76
261_Y	320_C	0.788	0.76
190_E	389_K	0.787	0.76
492_R	532_G	0.786	0.76
367_H	514_G	0.786	0.76
43_G	47_V	0.785	0.76
36_F	40_Q	0.784	0.76
105_L	560_K	0.784	0.76
417_L	420_L	0.780	0.75
116_V	156_A	0.779	0.75
115_I	146_L	0.779	0.75
137_I	246_L	0.779	0.75
320_C	324_R	0.778	0.75
476_I	548_R	0.778	0.75
151_H	511_A	0.774	0.75
321_A	325_Y	0.773	0.75
563_K	575_E	0.769	0.74
137_I	433_D	0.768	0.74
216_K	223_Y	0.767	0.74
404_L	408_K	0.767	0.74
371_M	441_D	0.766	0.74
323_Y	328_L	0.764	0.74
85_I	92_L	0.763	0.74
122_P	243_Y	0.763	0.74
143_V	147_E	0.760	0.73
337_I	366_H	0.759	0.73
381_K	384_A	0.755	0.73
31_S	40_Q	0.755	0.73
507_L	511_A	0.753	0.73
215_V	310_G	0.753	0.73
31_S	36_F	0.753	0.73
219_S	310_G	0.752	0.73
16_I	19_G	0.750	0.72
237_T	240_Q	0.749	0.72
213_Y	221_D	0.748	0.72
269_V	276_G	0.745	0.72
483_A	486_V	0.745	0.72
10_K	70_G	0.745	0.72
228_W	235_T	0.744	0.72
289_L	354_K	0.744	0.72
416_E	576_R	0.743	0.72
29_R	32_A	0.742	0.72
474_A	478_E	0.742	0.72
460_M	523_L	0.739	0.71
9_E	90_A	0.738	0.71
126_K	341_Q	0.738	0.71
468_L	563_K	0.737	0.71
266_P	305_Q	0.734	0.71
256_M	323_Y	0.734	0.71
402_R	417_L	0.734	0.71
320_C	345_L	0.733	0.71
208_E	211_R	0.733	0.71
142_A	146_L	0.732	0.71
162_W	262_N	0.732	0.71
29_R	40_Q	0.732	0.71
117_V	334_L	0.729	0.70
506_T	518_V	0.728	0.70
397_A	425_G	0.726	0.70
416_E	420_L	0.723	0.70
264_M	267_G	0.722	0.70
157_N	243_Y	0.722	0.70
286_V	301_G	0.722	0.70
125_A	166_F	0.722	0.70
158_H	323_Y	0.720	0.69
104_R	148_F	0.720	0.69
415_D	576_R	0.719	0.69
164_T	168_M	0.719	0.69
373_L	449_M	0.719	0.69
15_M	19_G	0.718	0.69
9_E	12_R	0.718	0.69
325_Y	333_V	0.717	0.69
530_F	533_F	0.716	0.69
133_L	162_W	0.716	0.69
171_A	206_F	0.715	0.69
28_V	72_A	0.715	0.69
229_R	232_V	0.714	0.69
289_L	292_F	0.714	0.69
135_S	433_D	0.713	0.69
137_I	248_V	0.710	0.68
542_A	545_E	0.709	0.68
373_L	443_I	0.707	0.68
476_I	556_Q	0.706	0.68
125_A	162_W	0.706	0.68
162_W	433_D	0.705	0.68
174_E	213_Y	0.705	0.68
125_A	433_D	0.703	0.68
156_A	254_D	0.703	0.68
138_I	369_F	0.701	0.67
281_S	314_T	0.701	0.67
34_V	495_Q	0.701	0.67
14_A	65_H	0.700	0.67
465_T	469_S	0.699	0.67
268_I	271_D	0.698	0.67
334_L	337_I	0.698	0.67
77_I	80_P	0.697	0.67
522_Y	561_T	0.697	0.67
43_G	62_V	0.697	0.67
493_E	496_L	0.697	0.67
10_K	16_I	0.696	0.67
279_V	286_V	0.696	0.67
237_T	241_I	0.696	0.67
509_V	512_R	0.691	0.66
149_L	508_T	0.690	0.66
157_N	336_Y	0.687	0.66
15_M	18_A	0.686	0.66
204_E	208_E	0.685	0.66
28_V	31_S	0.684	0.65
427_G	574_V	0.684	0.65
136_T	243_Y	0.684	0.65
542_A	548_R	0.681	0.65
165_Q	383_R	0.680	0.65
478_E	556_Q	0.679	0.65
269_V	305_Q	0.678	0.65
358_V	361_S	0.677	0.65
273_K	276_G	0.677	0.65
401_A	450_L	0.676	0.64
44_M	47_V	0.676	0.64
320_C	344_H	0.674	0.64
171_A	209_R	0.673	0.64
474_A	540_L	0.673	0.64
409_N	412_M	0.671	0.64
400_R	446_W	0.671	0.64
433_D	442_Y	0.669	0.64
325_Y	363_P	0.669	0.64
495_Q	532_G	0.668	0.64
563_K	573_T	0.668	0.64
261_Y	323_Y	0.667	0.63
333_V	364_L	0.667	0.63
460_M	562_L	0.666	0.63
175_K	203_D	0.665	0.63
372_M	380_F	0.665	0.63
99_A	561_T	0.664	0.63
492_R	537_C	0.664	0.63
369_F	438_R	0.663	0.63
226_E	230_K	0.663	0.63
413_P	576_R	0.662	0.63
203_D	209_R	0.661	0.63
228_W	335_Y	0.660	0.63
496_L	537_C	0.659	0.63
137_I	281_S	0.659	0.63
275_K	356_G	0.655	0.62
48_A	55_P	0.655	0.62
10_K	69_N	0.655	0.62
515_T	518_V	0.652	0.62
70_G	88_D	0.652	0.62
45_M	78_A	0.651	0.62
141_A	568_T	0.651	0.62
172_W	195_D	0.650	0.61
10_K	18_A	0.650	0.61
10_K	14_A	0.649	0.61
457_A	571_I	0.648	0.61
159_V	236_M	0.647	0.61
312_L	347_Q	0.646	0.61
267_G	322_K	0.645	0.61
214_V	218_Q	0.644	0.61
118_D	262_N	0.644	0.61
41_A	47_V	0.643	0.61
146_L	149_L	0.643	0.61
11_V	15_M	0.643	0.61
445_D	448_N	0.642	0.61
56_R	80_P	0.641	0.60
190_E	372_M	0.640	0.60
406_A	418_E	0.638	0.60
14_A	39_Y	0.638	0.60
15_M	44_M	0.637	0.60
18_A	65_H	0.636	0.60
97_Q	101_A	0.634	0.60
200_Y	207_A	0.633	0.59
290_D	298_E	0.633	0.59
389_K	392_D	0.633	0.59
126_K	157_N	0.632	0.59
455_N	528_G	0.632	0.59
122_P	126_K	0.629	0.59
428_A	452_F	0.629	0.59
11_V	21_P	0.629	0.59
162_W	344_H	0.628	0.59
10_K	20_A	0.628	0.59
120_S	124_V	0.628	0.59
405_V	408_K	0.627	0.59
108_A	149_L	0.627	0.59
167_G	210_A	0.626	0.59
92_L	501_L	0.625	0.58
10_K	72_A	0.625	0.58
63_L	75_V	0.624	0.58
340_R	378_K	0.624	0.58
325_Y	360_E	0.624	0.58
169_L	214_V	0.624	0.58
180_N	188_D	0.624	0.58
186_L	190_E	0.624	0.58
174_E	209_R	0.623	0.58
339_S	342_H	0.621	0.58
432_A	442_Y	0.620	0.58
54_A	58_L	0.619	0.58
133_L	246_L	0.619	0.58
333_V	362_V	0.618	0.58
47_V	62_V	0.617	0.57
129_H	393_L	0.617	0.57
246_L	394_L	0.615	0.57
563_K	567_D	0.614	0.57
119_Y	140_D	0.610	0.57
256_M	328_L	0.610	0.57
504_E	508_T	0.609	0.57
408_K	452_F	0.609	0.57
37_G	78_A	0.608	0.56
125_A	165_Q	0.607	0.56
495_Q	529_L	0.606	0.56
120_S	125_A	0.606	0.56
368_M	371_M	0.604	0.56
162_W	167_G	0.603	0.56
197_K	200_Y	0.602	0.56
562_L	573_T	0.602	0.56
289_L	347_Q	0.601	0.56
203_D	206_F	0.601	0.56
136_T	157_N	0.598	0.55
198_K	201_D	0.597	0.55
492_R	529_L	0.597	0.55
160_G	235_T	0.596	0.55
105_L	564_L	0.595	0.55
396_E	450_L	0.594	0.55
115_I	174_E	0.594	0.55
169_L	231_L	0.593	0.55
218_Q	311_Y	0.592	0.54
168_M	442_Y	0.591	0.54
33_K	37_G	0.591	0.54
129_H	440_T	0.590	0.54
269_V	278_A	0.590	0.54
90_A	94_E	0.587	0.54
70_G	73_S	0.587	0.54
13_Q	16_I	0.586	0.54
393_L	449_M	0.586	0.54
125_A	160_G	0.586	0.54
62_V	363_P	0.586	0.54
31_S	37_G	0.586	0.54
156_A	330_A	0.585	0.54
397_A	446_W	0.585	0.54
43_G	46_A	0.584	0.53
91_F	95_H	0.583	0.53
37_G	86_F	0.581	0.53
171_A	196_A	0.580	0.53
272_L	277_L	0.580	0.53
92_L	494_A	0.579	0.53
314_T	344_H	0.579	0.53
278_A	304_I	0.579	0.53
506_T	519_M	0.579	0.53
156_A	256_M	0.579	0.53
292_F	350_A	0.578	0.53
11_V	14_A	0.578	0.53
112_K	152_K	0.578	0.53
158_H	324_R	0.577	0.53
176_Q	206_F	0.577	0.53
261_Y	264_M	0.577	0.53
519_M	523_L	0.577	0.53
370_G	441_D	0.577	0.53
465_T	474_A	0.576	0.52
305_Q	312_L	0.576	0.52
397_A	450_L	0.575	0.52
102_S	560_K	0.575	0.52
55_P	59_A	0.574	0.52
260_L	263_P	0.573	0.52
343_Q	346_M	0.573	0.52
21_P	50_K	0.572	0.52
510_V	516_P	0.572	0.52
44_M	58_L	0.571	0.52
122_P	128_M	0.570	0.52
168_M	200_Y	0.570	0.52
488_I	551_R	0.569	0.52
187_A	191_G	0.568	0.51
158_H	320_C	0.568	0.51
105_L	557_L	0.567	0.51
228_W	344_H	0.567	0.51
325_Y	330_A	0.565	0.51
415_D	419_K	0.564	0.51
484_A	546_E	0.564	0.51
378_K	433_D	0.563	0.51
167_G	390_L	0.563	0.51
471_F	474_A	0.563	0.51
318_I	322_K	0.562	0.51
445_D	449_M	0.562	0.51
265_L	311_Y	0.562	0.51
125_A	167_G	0.561	0.51
162_W	324_R	0.561	0.51
461_Q	574_V	0.560	0.50
520_C	523_L	0.560	0.50
180_N	192_F	0.560	0.50
110_P	113_Q	0.559	0.50
424_V	469_S	0.559	0.50
339_S	441_D	0.558	0.50
71_I	88_D	0.558	0.50
115_I	332_R	0.558	0.50
344_H	370_G	0.557	0.50
502_Q	506_T	0.557	0.50
417_L	421_A	0.556	0.50
405_V	421_A	0.556	0.50
534_Y	540_L	0.556	0.50
272_L	276_G	0.555	0.50
229_R	237_T	0.554	0.50
44_M	77_I	0.554	0.50
181_A	188_D	0.554	0.50
269_V	272_L	0.554	0.50
48_A	51_L	0.553	0.50
41_A	85_I	0.553	0.50
412_M	417_L	0.552	0.49
135_S	138_I	0.552	0.49
169_L	189_L	0.550	0.49
547_V	551_R	0.550	0.49
457_A	461_Q	0.550	0.49
41_A	45_M	0.550	0.49
348_A	351_I	0.549	0.49
278_A	305_Q	0.549	0.49
400_R	404_L	0.549	0.49
321_A	348_A	0.549	0.49
423_A	464_Y	0.548	0.49
435_S	517_H	0.548	0.49
77_I	83_I	0.547	0.49
127_E	391_A	0.547	0.49
128_M	343_Q	0.547	0.49
166_F	261_Y	0.546	0.49
455_N	524_Y	0.546	0.49
106_G	564_L	0.545	0.49
271_D	356_G	0.545	0.49
369_F	390_L	0.545	0.49
96_V	100_L	0.545	0.49
147_E	152_K	0.543	0.48
522_Y	565_G	0.542	0.48
352_V	357_Y	0.542	0.48
87_L	501_L	0.542	0.48
335_Y	345_L	0.541	0.48
396_E	447_D	0.540	0.48
467_V	558_T	0.540	0.48
264_M	323_Y	0.539	0.48
11_V	16_I	0.539	0.48
230_K	234_I	0.539	0.48
266_P	273_K	0.539	0.48
27_Q	46_A	0.538	0.48
548_R	556_Q	0.537	0.48
186_L	234_I	0.537	0.48
241_I	391_A	0.537	0.48
11_V	66_L	0.537	0.48
217_L	228_W	0.536	0.47
126_K	370_G	0.535	0.47
463_A	470_V	0.535	0.47
156_A	324_R	0.535	0.47
93_A	497_A	0.535	0.47
378_K	396_E	0.534	0.47
119_Y	426_I	0.534	0.47
120_S	166_F	0.533	0.47
17_A	94_E	0.533	0.47
324_R	433_D	0.532	0.47
117_V	146_L	0.532	0.47
256_M	320_C	0.532	0.47
374_G	442_Y	0.531	0.47
553_K	557_L	0.531	0.47
157_N	261_Y	0.531	0.47
277_L	355_A	0.530	0.47
119_Y	135_S	0.530	0.47
40_Q	43_G	0.530	0.47
380_F	386_G	0.530	0.47
120_S	228_W	0.530	0.47
160_G	344_H	0.529	0.47
127_E	338_D	0.528	0.46
459_Y	534_Y	0.528	0.46
90_A	406_A	0.528	0.46
156_A	328_L	0.528	0.46
157_N	366_H	0.527	0.46
8_S	25_E	0.527	0.46
405_V	412_M	0.526	0.46
118_D	433_D	0.526	0.46
100_L	557_L	0.525	0.46
39_Y	407_E	0.524	0.46
474_A	477_D	0.524	0.46
96_V	307_K	0.524	0.46
395_D	422_N	0.524	0.46
217_L	390_L	0.524	0.46
162_W	210_A	0.524	0.46
316_T	381_K	0.523	0.46
162_W	166_F	0.523	0.46
345_L	368_M	0.522	0.46
118_D	334_L	0.521	0.46
26_P	31_S	0.521	0.46
19_G	61_Q	0.521	0.46
140_D	555_A	0.521	0.46
168_M	302_V	0.521	0.46
372_M	439_T	0.521	0.46
29_R	43_G	0.520	0.45
148_F	567_D	0.519	0.45
196_A	210_A	0.517	0.45
459_Y	463_A	0.516	0.45
505_E	508_T	0.516	0.45
200_Y	204_E	0.515	0.45
431_Y	520_C	0.515	0.45
132_H	370_G	0.514	0.45
238_Q	242_T	0.514	0.45
477_D	481_L	0.513	0.45
8_S	16_I	0.512	0.44
124_V	232_V	0.511	0.44
335_Y	364_L	0.511	0.44
11_V	85_I	0.511	0.44
247_N	425_G	0.510	0.44
102_S	106_G	0.509	0.44
470_V	530_F	0.508	0.44
391_A	395_D	0.508	0.44
352_V	360_E	0.508	0.44
12_R	22_A	0.508	0.44
289_L	351_I	0.507	0.44
337_I	437_N	0.506	0.44
63_L	67_D	0.506	0.44
117_V	155_R	0.506	0.44
374_G	449_M	0.505	0.44
32_A	37_G	0.505	0.44
12_R	19_G	0.504	0.43
39_Y	45_M	0.504	0.43
341_Q	366_H	0.504	0.43
13_Q	549_N	0.504	0.43
217_L	225_R	0.503	0.43
321_A	324_R	0.503	0.43
160_G	433_D	0.503	0.43
11_V	17_A	0.503	0.43
460_M	565_G	0.502	0.43
401_A	421_A	0.502	0.43
247_N	403_R	0.502	0.43
337_I	340_R	0.502	0.43
172_W	206_F	0.501	0.43
105_L	504_E	0.501	0.43
157_N	335_Y	0.501	0.43
345_L	382_T	0.500	0.43
372_M	441_D	0.500	0.43
428_A	461_Q	0.500	0.43
489_R	547_V	0.500	0.43

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4obyA	1	0.9775	100	0.248	Contact Map
4r3zB	1	0.9827	100	0.26	Contact Map
4q2tA	1	0.9827	100	0.27	Contact Map
1f7uA	1	0.974	100	0.278	Contact Map
2zueA	1	0.9809	100	0.304	Contact Map
1iq0A	1	0.9428	100	0.319	Contact Map
3fnrA	1	0.7608	100	0.547	Contact Map
3tqoA	1	0.5979	100	0.742	Contact Map
3h99A	1	0.6464	100	0.758	Contact Map
3sp1A	1	0.5945	100	0.76	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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