GREMLIN Database
SYR - Arginine--tRNA ligase
UniProt: P11875 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10071
Length: 577 (557)
Sequences: 2678 (1754)
Seq/√Len: 74.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
114_T152_K5.7191.00
523_L565_G5.5041.00
270_A274_A4.8661.00
60_E64_T4.0061.00
245_R422_N3.9541.00
216_K221_D3.9431.00
175_K209_R3.8231.00
245_R395_D3.8011.00
53_M61_Q3.6001.00
273_K285_T3.4911.00
145_T568_T3.4421.00
402_R418_E3.4361.00
271_D275_K3.4071.00
54_A57_Q3.1821.00
215_V219_S2.9461.00
337_I345_L2.8511.00
74_K86_F2.8451.00
147_E155_R2.8401.00
240_Q244_D2.8241.00
394_L429_V2.7831.00
212_N216_K2.7041.00
63_L83_I2.6681.00
406_A417_L2.6621.00
538_P541_S2.5881.00
375_K445_D2.5531.00
464_Y573_T2.5041.00
350_A353_R2.4951.00
467_V555_A2.4891.00
143_V155_R2.4581.00
279_V288_F2.4531.00
353_R362_V2.4371.00
135_S369_F2.4271.00
174_E223_Y2.4021.00
321_A352_V2.3741.00
195_D198_K2.3201.00
195_D199_H2.3041.00
419_K423_A2.2961.00
270_A273_K2.2961.00
402_R406_A2.2841.00
499_R529_L2.2411.00
213_Y224_F2.2341.00
420_L424_V2.2241.00
503_F564_L2.2071.00
141_A144_R2.1801.00
117_V142_A2.1611.00
113_Q332_R2.1571.00
222_E226_E2.1471.00
113_Q331_D2.1351.00
464_Y468_L2.1321.00
400_R403_R2.1291.00
539_I555_A2.1241.00
247_N572_E2.1111.00
349_W364_L2.1111.00
267_G326_E2.0741.00
149_L511_A2.0741.00
89_P494_A2.0531.00
423_A572_E2.0221.00
416_E419_K2.0121.00
73_S88_D1.9751.00
266_P270_A1.9561.00
199_H202_E1.9371.00
522_Y526_L1.9371.00
56_R79_G1.9291.00
365_E514_G1.9261.00
208_E212_N1.9161.00
464_Y563_K1.8951.00
507_L568_T1.8831.00
16_I22_A1.8651.00
229_R233_D1.8621.00
332_R365_E1.8491.00
99_A500_L1.8481.00
396_E400_R1.8481.00
446_W450_L1.8271.00
302_V314_T1.8141.00
510_V519_M1.8131.00
431_Y455_N1.8071.00
422_N572_E1.7971.00
464_Y559_A1.7961.00
273_K305_Q1.7861.00
400_R447_D1.7841.00
530_F555_A1.7841.00
472_R575_E1.7491.00
287_V351_I1.7431.00
114_T154_I1.7321.00
120_S136_T1.7291.00
499_R502_Q1.7271.00
120_S243_Y1.7251.00
468_L559_A1.7051.00
148_F564_L1.7031.00
427_G461_Q1.7021.00
398_L422_N1.6901.00
340_R371_M1.6801.00
140_D144_R1.6701.00
291_E354_K1.6511.00
104_R107_V1.6331.00
271_D357_Y1.6331.00
278_A285_T1.6321.00
233_D237_T1.6271.00
323_Y327_T1.6171.00
560_K564_L1.6050.99
245_R398_L1.6010.99
175_K199_H1.5990.99
198_K202_E1.5980.99
222_E229_R1.5910.99
419_K422_N1.5770.99
268_I322_K1.5700.99
280_E285_T1.5690.99
494_A498_A1.5600.99
373_L441_D1.5410.99
225_R229_R1.5360.99
413_P416_E1.5270.99
564_L567_D1.5170.99
57_Q61_Q1.5160.99
176_Q199_H1.5140.99
398_L418_E1.5060.99
89_P491_D1.5020.99
312_L315_T1.5020.99
148_F503_F1.5010.99
115_I151_H1.4970.99
254_D328_L1.4830.99
212_N215_V1.4810.99
146_L514_G1.4790.99
61_Q64_T1.4750.99
502_Q505_E1.4680.99
39_Y87_L1.4660.99
556_Q560_K1.4530.99
523_L562_L1.4490.99
474_A552_L1.4470.99
496_L558_T1.4300.99
271_D274_A1.4210.99
146_L511_A1.4210.99
267_G270_A1.4120.99
28_V39_Y1.4100.99
500_L561_T1.4090.99
142_A367_H1.4060.99
56_R60_E1.4050.99
490_E493_E1.4040.99
468_L575_E1.4010.99
32_A36_F1.3990.99
431_Y524_Y1.3930.98
221_D224_F1.3920.98
399_E403_R1.3860.98
545_E548_R1.3780.98
272_L355_A1.3740.98
149_L507_L1.3700.98
119_Y155_R1.3630.98
9_E13_Q1.3580.98
171_A213_Y1.3540.98
334_L367_H1.3500.98
467_V530_F1.3480.98
145_T510_V1.3470.98
395_D399_E1.3430.98
302_V348_A1.3420.98
509_V513_E1.3410.98
463_A531_S1.3380.98
235_T239_N1.3370.98
271_D322_K1.3340.98
76_E86_F1.3300.98
470_V539_I1.3300.98
171_A210_A1.3290.98
292_F354_K1.3220.98
260_L323_Y1.3190.98
519_M565_G1.3170.98
540_L548_R1.3160.98
119_Y143_V1.3150.98
112_K151_H1.3140.98
487_I547_V1.3070.98
245_R394_L1.2880.97
242_T391_A1.2810.97
267_G271_D1.2710.97
140_D430_K1.2680.97
303_I314_T1.2660.97
524_Y528_G1.2650.97
13_Q17_A1.2650.97
62_V83_I1.2620.97
302_V351_I1.2610.97
488_I550_S1.2590.97
458_P577_M1.2530.97
144_R567_D1.2500.97
172_W192_F1.2490.97
334_L514_G1.2460.97
14_A18_A1.2430.97
116_V330_A1.2400.97
398_L402_R1.2400.97
428_A458_P1.2390.97
191_G195_D1.2330.97
423_A574_V1.2320.97
350_A354_K1.2310.97
339_S368_M1.2290.97
73_S89_P1.2290.97
196_A206_F1.2280.97
546_E549_N1.2250.97
404_L407_E1.2230.97
184_M187_A1.2210.97
285_T305_Q1.2150.96
117_V153_V1.2060.96
53_M57_Q1.2050.96
462_Y531_S1.2040.96
156_A320_C1.2000.96
63_L77_I1.1980.96
414_A418_E1.1980.96
190_E387_T1.1910.96
140_D570_G1.1850.96
566_L571_I1.1840.96
268_I319_A1.1790.96
402_R421_A1.1730.96
321_A335_Y1.1700.96
499_R525_D1.1690.96
322_K326_E1.1600.95
145_T511_A1.1600.95
526_L558_T1.1590.95
56_R77_I1.1580.95
236_M255_V1.1560.95
545_E549_N1.1560.95
533_F537_C1.1540.95
314_T348_A1.1500.95
541_S548_R1.1490.95
177_Q180_N1.1480.95
130_V393_L1.1480.95
314_T351_I1.1420.95
273_K280_E1.1350.95
117_V143_V1.1330.95
338_D342_H1.1310.95
269_V304_I1.1290.95
398_L426_I1.1230.94
542_A547_V1.1220.94
358_V364_L1.1200.94
68_L72_A1.1150.94
273_K278_A1.1140.94
172_W175_K1.1140.94
493_E551_R1.1050.94
199_H203_D1.1050.94
51_L58_L1.1040.94
477_D480_Q1.0980.94
343_Q347_Q1.0970.94
234_I237_T1.0960.94
53_M58_L1.0920.94
172_W196_A1.0890.93
238_Q241_I1.0820.93
97_Q100_L1.0760.93
403_R406_A1.0740.93
17_A65_H1.0730.93
500_L526_L1.0730.93
336_Y367_H1.0720.93
168_M196_A1.0680.93
75_V85_I1.0680.93
201_D384_A1.0660.93
491_D495_Q1.0630.93
38_D498_A1.0630.93
12_R16_I1.0620.93
147_E249_T1.0610.93
180_N183_E1.0590.92
281_S286_V1.0540.92
188_D192_F1.0520.92
44_M62_V1.0510.92
452_F458_P1.0500.92
321_A360_E1.0460.92
332_R363_P1.0450.92
144_R147_E1.0430.92
492_R536_H1.0430.92
537_C551_R1.0420.92
107_V148_F1.0410.92
530_F534_Y1.0310.91
330_A333_V1.0290.91
47_V58_L1.0290.91
334_L365_E1.0290.91
188_D191_G1.0250.91
538_P542_A1.0180.91
338_D371_M1.0130.91
419_K572_E1.0130.91
342_H346_M1.0130.91
398_L425_G1.0110.91
33_K36_F1.0090.91
269_V273_K1.0090.91
472_R576_R1.0060.90
405_V409_N1.0050.90
38_D494_A1.0050.90
147_E153_V1.0050.90
244_D249_T1.0040.90
435_S448_N1.0030.90
120_S157_N1.0020.90
94_E97_Q0.9990.90
403_R407_E0.9980.90
324_R335_Y0.9980.90
397_A400_R0.9970.90
66_L75_V0.9950.90
566_L573_T0.9910.90
56_R78_A0.9900.90
490_E537_C0.9840.89
318_I352_V0.9810.89
129_H372_M0.9790.89
503_F507_L0.9780.89
396_E446_W0.9780.89
342_H368_M0.9780.89
171_A175_K0.9760.89
300_M343_Q0.9720.89
116_V333_V0.9710.89
423_A427_G0.9680.89
424_V458_P0.9670.89
133_L433_D0.9670.89
213_Y216_K0.9670.89
556_Q559_A0.9660.89
465_T468_L0.9660.89
268_I318_I0.9650.89
414_A417_L0.9620.88
499_R526_L0.9610.88
337_I368_M0.9590.88
99_A557_L0.9580.88
197_K201_D0.9540.88
142_A336_Y0.9540.88
72_A75_V0.9520.88
10_K13_Q0.9470.88
470_V555_A0.9460.88
250_L253_D0.9410.87
503_F565_G0.9330.87
464_Y575_E0.9290.87
324_R333_V0.9280.86
489_R550_S0.9180.86
134_R433_D0.9150.86
308_D312_L0.9140.86
57_Q60_E0.9140.86
158_H261_Y0.9080.85
88_D91_F0.9070.85
8_S12_R0.9040.85
10_K17_A0.9020.85
172_W176_Q0.9010.85
95_H98_Q0.8980.85
543_E547_V0.8970.85
405_V410_P0.8970.85
178_Q230_K0.8960.85
311_Y316_T0.8950.84
503_F561_T0.8950.84
291_E350_A0.8950.84
265_L269_V0.8940.84
559_A563_K0.8930.84
403_R447_D0.8900.84
218_Q316_T0.8900.84
265_L316_T0.8890.84
475_E478_E0.8880.84
421_A425_G0.8870.84
67_D74_K0.8860.84
271_D355_A0.8850.84
8_S11_V0.8830.84
220_G225_R0.8830.84
425_G429_V0.8820.84
173_L231_L0.8760.83
11_V41_A0.8740.83
164_T306_K0.8730.83
396_E399_E0.8730.83
87_L92_L0.8700.83
11_V62_V0.8700.83
59_A77_I0.8690.83
204_E207_A0.8660.82
469_S472_R0.8660.82
178_Q182_G0.8660.82
15_M20_A0.8660.82
34_V37_G0.8640.82
271_D326_E0.8640.82
303_I312_L0.8570.82
325_Y329_H0.8560.82
205_E208_E0.8560.82
30_Q502_Q0.8560.82
227_M231_L0.8540.82
508_T512_R0.8530.81
240_Q255_V0.8490.81
322_K357_Y0.8470.81
122_P228_W0.8440.81
335_Y349_W0.8440.81
179_E183_E0.8420.81
335_Y344_H0.8420.81
265_L272_L0.8400.80
159_V255_V0.8360.80
496_L526_L0.8350.80
165_Q382_T0.8350.80
493_E554_L0.8340.80
325_Y362_V0.8340.80
41_A44_M0.8340.80
468_L472_R0.8320.80
199_H206_F0.8300.80
368_M439_T0.8290.80
44_M59_A0.8250.79
122_P157_N0.8250.79
557_L560_K0.8240.79
179_E182_G0.8240.79
151_H332_R0.8240.79
462_Y534_Y0.8220.79
467_V559_A0.8180.79
91_F94_E0.8160.79
100_L556_Q0.8160.79
168_M197_K0.8150.78
223_Y226_E0.8140.78
61_Q65_H0.8120.78
72_A85_I0.8110.78
397_A429_V0.8080.78
133_L137_I0.8080.78
326_E329_H0.8070.78
500_L558_T0.8060.78
281_S284_A0.8050.78
282_E307_K0.8010.77
493_E537_C0.7980.77
437_N440_T0.7970.77
181_A230_K0.7970.77
506_T509_V0.7930.77
117_V336_Y0.7910.76
256_M259_S0.7910.76
464_Y574_V0.7910.76
100_L553_K0.7900.76
180_N191_G0.7890.76
113_Q151_H0.7880.76
261_Y320_C0.7880.76
190_E389_K0.7870.76
492_R532_G0.7860.76
367_H514_G0.7860.76
43_G47_V0.7850.76
36_F40_Q0.7840.76
105_L560_K0.7840.76
417_L420_L0.7800.75
116_V156_A0.7790.75
115_I146_L0.7790.75
137_I246_L0.7790.75
320_C324_R0.7780.75
476_I548_R0.7780.75
151_H511_A0.7740.75
321_A325_Y0.7730.75
563_K575_E0.7690.74
137_I433_D0.7680.74
216_K223_Y0.7670.74
404_L408_K0.7670.74
371_M441_D0.7660.74
323_Y328_L0.7640.74
85_I92_L0.7630.74
122_P243_Y0.7630.74
143_V147_E0.7600.73
337_I366_H0.7590.73
381_K384_A0.7550.73
31_S40_Q0.7550.73
507_L511_A0.7530.73
215_V310_G0.7530.73
31_S36_F0.7530.73
219_S310_G0.7520.73
16_I19_G0.7500.72
237_T240_Q0.7490.72
213_Y221_D0.7480.72
269_V276_G0.7450.72
483_A486_V0.7450.72
10_K70_G0.7450.72
228_W235_T0.7440.72
289_L354_K0.7440.72
416_E576_R0.7430.72
29_R32_A0.7420.72
474_A478_E0.7420.72
460_M523_L0.7390.71
9_E90_A0.7380.71
126_K341_Q0.7380.71
468_L563_K0.7370.71
266_P305_Q0.7340.71
256_M323_Y0.7340.71
402_R417_L0.7340.71
320_C345_L0.7330.71
208_E211_R0.7330.71
142_A146_L0.7320.71
162_W262_N0.7320.71
29_R40_Q0.7320.71
117_V334_L0.7290.70
506_T518_V0.7280.70
397_A425_G0.7260.70
416_E420_L0.7230.70
264_M267_G0.7220.70
157_N243_Y0.7220.70
286_V301_G0.7220.70
125_A166_F0.7220.70
158_H323_Y0.7200.69
104_R148_F0.7200.69
415_D576_R0.7190.69
164_T168_M0.7190.69
373_L449_M0.7190.69
15_M19_G0.7180.69
9_E12_R0.7180.69
325_Y333_V0.7170.69
530_F533_F0.7160.69
133_L162_W0.7160.69
171_A206_F0.7150.69
28_V72_A0.7150.69
229_R232_V0.7140.69
289_L292_F0.7140.69
135_S433_D0.7130.69
137_I248_V0.7100.68
542_A545_E0.7090.68
373_L443_I0.7070.68
476_I556_Q0.7060.68
125_A162_W0.7060.68
162_W433_D0.7050.68
174_E213_Y0.7050.68
125_A433_D0.7030.68
156_A254_D0.7030.68
138_I369_F0.7010.67
281_S314_T0.7010.67
34_V495_Q0.7010.67
14_A65_H0.7000.67
465_T469_S0.6990.67
268_I271_D0.6980.67
334_L337_I0.6980.67
77_I80_P0.6970.67
522_Y561_T0.6970.67
43_G62_V0.6970.67
493_E496_L0.6970.67
10_K16_I0.6960.67
279_V286_V0.6960.67
237_T241_I0.6960.67
509_V512_R0.6910.66
149_L508_T0.6900.66
157_N336_Y0.6870.66
15_M18_A0.6860.66
204_E208_E0.6850.66
28_V31_S0.6840.65
427_G574_V0.6840.65
136_T243_Y0.6840.65
542_A548_R0.6810.65
165_Q383_R0.6800.65
478_E556_Q0.6790.65
269_V305_Q0.6780.65
358_V361_S0.6770.65
273_K276_G0.6770.65
401_A450_L0.6760.64
44_M47_V0.6760.64
320_C344_H0.6740.64
171_A209_R0.6730.64
474_A540_L0.6730.64
409_N412_M0.6710.64
400_R446_W0.6710.64
433_D442_Y0.6690.64
325_Y363_P0.6690.64
495_Q532_G0.6680.64
563_K573_T0.6680.64
261_Y323_Y0.6670.63
333_V364_L0.6670.63
460_M562_L0.6660.63
175_K203_D0.6650.63
372_M380_F0.6650.63
99_A561_T0.6640.63
492_R537_C0.6640.63
369_F438_R0.6630.63
226_E230_K0.6630.63
413_P576_R0.6620.63
203_D209_R0.6610.63
228_W335_Y0.6600.63
496_L537_C0.6590.63
137_I281_S0.6590.63
275_K356_G0.6550.62
48_A55_P0.6550.62
10_K69_N0.6550.62
515_T518_V0.6520.62
70_G88_D0.6520.62
45_M78_A0.6510.62
141_A568_T0.6510.62
172_W195_D0.6500.61
10_K18_A0.6500.61
10_K14_A0.6490.61
457_A571_I0.6480.61
159_V236_M0.6470.61
312_L347_Q0.6460.61
267_G322_K0.6450.61
214_V218_Q0.6440.61
118_D262_N0.6440.61
41_A47_V0.6430.61
146_L149_L0.6430.61
11_V15_M0.6430.61
445_D448_N0.6420.61
56_R80_P0.6410.60
190_E372_M0.6400.60
406_A418_E0.6380.60
14_A39_Y0.6380.60
15_M44_M0.6370.60
18_A65_H0.6360.60
97_Q101_A0.6340.60
200_Y207_A0.6330.59
290_D298_E0.6330.59
389_K392_D0.6330.59
126_K157_N0.6320.59
455_N528_G0.6320.59
122_P126_K0.6290.59
428_A452_F0.6290.59
11_V21_P0.6290.59
162_W344_H0.6280.59
10_K20_A0.6280.59
120_S124_V0.6280.59
405_V408_K0.6270.59
108_A149_L0.6270.59
167_G210_A0.6260.59
92_L501_L0.6250.58
10_K72_A0.6250.58
63_L75_V0.6240.58
340_R378_K0.6240.58
325_Y360_E0.6240.58
169_L214_V0.6240.58
180_N188_D0.6240.58
186_L190_E0.6240.58
174_E209_R0.6230.58
339_S342_H0.6210.58
432_A442_Y0.6200.58
54_A58_L0.6190.58
133_L246_L0.6190.58
333_V362_V0.6180.58
47_V62_V0.6170.57
129_H393_L0.6170.57
246_L394_L0.6150.57
563_K567_D0.6140.57
119_Y140_D0.6100.57
256_M328_L0.6100.57
504_E508_T0.6090.57
408_K452_F0.6090.57
37_G78_A0.6080.56
125_A165_Q0.6070.56
495_Q529_L0.6060.56
120_S125_A0.6060.56
368_M371_M0.6040.56
162_W167_G0.6030.56
197_K200_Y0.6020.56
562_L573_T0.6020.56
289_L347_Q0.6010.56
203_D206_F0.6010.56
136_T157_N0.5980.55
198_K201_D0.5970.55
492_R529_L0.5970.55
160_G235_T0.5960.55
105_L564_L0.5950.55
396_E450_L0.5940.55
115_I174_E0.5940.55
169_L231_L0.5930.55
218_Q311_Y0.5920.54
168_M442_Y0.5910.54
33_K37_G0.5910.54
129_H440_T0.5900.54
269_V278_A0.5900.54
90_A94_E0.5870.54
70_G73_S0.5870.54
13_Q16_I0.5860.54
393_L449_M0.5860.54
125_A160_G0.5860.54
62_V363_P0.5860.54
31_S37_G0.5860.54
156_A330_A0.5850.54
397_A446_W0.5850.54
43_G46_A0.5840.53
91_F95_H0.5830.53
37_G86_F0.5810.53
171_A196_A0.5800.53
272_L277_L0.5800.53
92_L494_A0.5790.53
314_T344_H0.5790.53
278_A304_I0.5790.53
506_T519_M0.5790.53
156_A256_M0.5790.53
292_F350_A0.5780.53
11_V14_A0.5780.53
112_K152_K0.5780.53
158_H324_R0.5770.53
176_Q206_F0.5770.53
261_Y264_M0.5770.53
519_M523_L0.5770.53
370_G441_D0.5770.53
465_T474_A0.5760.52
305_Q312_L0.5760.52
397_A450_L0.5750.52
102_S560_K0.5750.52
55_P59_A0.5740.52
260_L263_P0.5730.52
343_Q346_M0.5730.52
21_P50_K0.5720.52
510_V516_P0.5720.52
44_M58_L0.5710.52
122_P128_M0.5700.52
168_M200_Y0.5700.52
488_I551_R0.5690.52
187_A191_G0.5680.51
158_H320_C0.5680.51
105_L557_L0.5670.51
228_W344_H0.5670.51
325_Y330_A0.5650.51
415_D419_K0.5640.51
484_A546_E0.5640.51
378_K433_D0.5630.51
167_G390_L0.5630.51
471_F474_A0.5630.51
318_I322_K0.5620.51
445_D449_M0.5620.51
265_L311_Y0.5620.51
125_A167_G0.5610.51
162_W324_R0.5610.51
461_Q574_V0.5600.50
520_C523_L0.5600.50
180_N192_F0.5600.50
110_P113_Q0.5590.50
424_V469_S0.5590.50
339_S441_D0.5580.50
71_I88_D0.5580.50
115_I332_R0.5580.50
344_H370_G0.5570.50
502_Q506_T0.5570.50
417_L421_A0.5560.50
405_V421_A0.5560.50
534_Y540_L0.5560.50
272_L276_G0.5550.50
229_R237_T0.5540.50
44_M77_I0.5540.50
181_A188_D0.5540.50
269_V272_L0.5540.50
48_A51_L0.5530.50
41_A85_I0.5530.50
412_M417_L0.5520.49
135_S138_I0.5520.49
169_L189_L0.5500.49
547_V551_R0.5500.49
457_A461_Q0.5500.49
41_A45_M0.5500.49
348_A351_I0.5490.49
278_A305_Q0.5490.49
400_R404_L0.5490.49
321_A348_A0.5490.49
423_A464_Y0.5480.49
435_S517_H0.5480.49
77_I83_I0.5470.49
127_E391_A0.5470.49
128_M343_Q0.5470.49
166_F261_Y0.5460.49
455_N524_Y0.5460.49
106_G564_L0.5450.49
271_D356_G0.5450.49
369_F390_L0.5450.49
96_V100_L0.5450.49
147_E152_K0.5430.48
522_Y565_G0.5420.48
352_V357_Y0.5420.48
87_L501_L0.5420.48
335_Y345_L0.5410.48
396_E447_D0.5400.48
467_V558_T0.5400.48
264_M323_Y0.5390.48
11_V16_I0.5390.48
230_K234_I0.5390.48
266_P273_K0.5390.48
27_Q46_A0.5380.48
548_R556_Q0.5370.48
186_L234_I0.5370.48
241_I391_A0.5370.48
11_V66_L0.5370.48
217_L228_W0.5360.47
126_K370_G0.5350.47
463_A470_V0.5350.47
156_A324_R0.5350.47
93_A497_A0.5350.47
378_K396_E0.5340.47
119_Y426_I0.5340.47
120_S166_F0.5330.47
17_A94_E0.5330.47
324_R433_D0.5320.47
117_V146_L0.5320.47
256_M320_C0.5320.47
374_G442_Y0.5310.47
553_K557_L0.5310.47
157_N261_Y0.5310.47
277_L355_A0.5300.47
119_Y135_S0.5300.47
40_Q43_G0.5300.47
380_F386_G0.5300.47
120_S228_W0.5300.47
160_G344_H0.5290.47
127_E338_D0.5280.46
459_Y534_Y0.5280.46
90_A406_A0.5280.46
156_A328_L0.5280.46
157_N366_H0.5270.46
8_S25_E0.5270.46
405_V412_M0.5260.46
118_D433_D0.5260.46
100_L557_L0.5250.46
39_Y407_E0.5240.46
474_A477_D0.5240.46
96_V307_K0.5240.46
395_D422_N0.5240.46
217_L390_L0.5240.46
162_W210_A0.5240.46
316_T381_K0.5230.46
162_W166_F0.5230.46
345_L368_M0.5220.46
118_D334_L0.5210.46
26_P31_S0.5210.46
19_G61_Q0.5210.46
140_D555_A0.5210.46
168_M302_V0.5210.46
372_M439_T0.5210.46
29_R43_G0.5200.45
148_F567_D0.5190.45
196_A210_A0.5170.45
459_Y463_A0.5160.45
505_E508_T0.5160.45
200_Y204_E0.5150.45
431_Y520_C0.5150.45
132_H370_G0.5140.45
238_Q242_T0.5140.45
477_D481_L0.5130.45
8_S16_I0.5120.44
124_V232_V0.5110.44
335_Y364_L0.5110.44
11_V85_I0.5110.44
247_N425_G0.5100.44
102_S106_G0.5090.44
470_V530_F0.5080.44
391_A395_D0.5080.44
352_V360_E0.5080.44
12_R22_A0.5080.44
289_L351_I0.5070.44
337_I437_N0.5060.44
63_L67_D0.5060.44
117_V155_R0.5060.44
374_G449_M0.5050.44
32_A37_G0.5050.44
12_R19_G0.5040.43
39_Y45_M0.5040.43
341_Q366_H0.5040.43
13_Q549_N0.5040.43
217_L225_R0.5030.43
321_A324_R0.5030.43
160_G433_D0.5030.43
11_V17_A0.5030.43
460_M565_G0.5020.43
401_A421_A0.5020.43
247_N403_R0.5020.43
337_I340_R0.5020.43
172_W206_F0.5010.43
105_L504_E0.5010.43
157_N335_Y0.5010.43
345_L382_T0.5000.43
372_M441_D0.5000.43
428_A461_Q0.5000.43
489_R547_V0.5000.43
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4obyA 1 0.9775 100 0.248 Contact Map
4r3zB 1 0.9827 100 0.26 Contact Map
4q2tA 1 0.9827 100 0.27 Contact Map
1f7uA 1 0.974 100 0.278 Contact Map
2zueA 1 0.9809 100 0.304 Contact Map
1iq0A 1 0.9428 100 0.319 Contact Map
3fnrA 1 0.7608 100 0.547 Contact Map
3tqoA 1 0.5979 100 0.742 Contact Map
3h99A 1 0.6464 100 0.758 Contact Map
3sp1A 1 0.5945 100 0.76 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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