ARGO - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

ARGO - Arginine exporter protein ArgO

UniProt:	P11667	Sequences: MFSYYFQGLALGAAMILPLGPQNAFVMNQGIRRQYHIMIALLCAISDLVLICAGIFGGSALLMQSPWLLALVTWGGVAFLLWYGFGAFKTAMSSNIELASAEVMKQGRWKIIATMLAVTWLNPHVYLDTFVVLGSLGGQLDVEPKRWFALGTISASFLWFFGLALLAAWLAPRLRTAKAQRIINLVVGCVMWFIALQLARDGIAHAQALFS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11159
Length:	211 (194)
Sequences:	11916 (8605)
Seq/√Len:	617.8

ECOLI - ARGO RHTC YAHN LEUE RHTB EAMB
BACSU - YISU YRHP YCGF
SULSO - Q97ZW7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
45_I	112_I	5.085	1.00
84_G	192_W	3.587	1.00
85_F	89_K	3.142	1.00
182_I	185_L	2.868	1.00
70_A	73_T	2.755	1.00
81_L	195_A	2.554	1.00
146_R	150_L	2.513	1.00
109_W	113_A	2.440	1.00
143_E	146_R	2.356	1.00
38_M	108_R	2.252	1.00
74_W	78_A	2.229	1.00
181_R	185_L	2.203	1.00
88_F	185_L	2.178	1.00
30_G	36_H	2.116	1.00
77_V	199_A	2.086	1.00
82_W	86_G	2.084	1.00
88_F	188_G	2.077	1.00
49_V	116_L	2.020	1.00
11_L	132_V	2.019	1.00
25_F	39_I	1.944	1.00
144_P	147_W	1.919	1.00
86_G	89_K	1.918	1.00
84_G	188_G	1.842	1.00
189_C	193_F	1.821	1.00
77_V	195_A	1.813	1.00
143_E	147_W	1.771	1.00
46_S	120_W	1.767	1.00
22_Q	43_C	1.767	1.00
9_L	155_A	1.759	1.00
23_N	163_L	1.702	1.00
81_L	192_W	1.688	1.00
35_Y	111_I	1.652	1.00
171_A	175_R	1.632	1.00
67_W	70_A	1.628	1.00
91_A	185_L	1.624	1.00
156_S	160_F	1.608	1.00
36_H	164_A	1.577	1.00
16_I	155_A	1.557	1.00
36_H	40_A	1.503	1.00
92_M	185_L	1.495	1.00
30_G	164_A	1.485	1.00
146_R	149_A	1.480	1.00
145_K	149_A	1.464	1.00
113_A	117_A	1.462	1.00
69_L	73_T	1.455	1.00
70_A	74_W	1.445	1.00
60_A	64_Q	1.434	1.00
41_L	112_I	1.426	1.00
81_L	85_F	1.404	1.00
147_W	150_L	1.394	1.00
182_I	186_V	1.391	1.00
26_V	30_G	1.350	1.00
29_Q	39_I	1.345	1.00
17_L	159_W	1.342	1.00
22_Q	119_T	1.334	1.00
67_W	71_L	1.299	1.00
27_M	167_A	1.298	1.00
107_G	110_K	1.292	1.00
116_L	120_W	1.291	1.00
112_I	116_L	1.276	1.00
25_F	118_V	1.274	1.00
74_W	77_V	1.262	1.00
79_F	83_Y	1.261	1.00
37_I	165_L	1.257	1.00
40_A	164_A	1.249	1.00
74_W	199_A	1.218	1.00
8_G	12_G	1.207	1.00
47_D	119_T	1.204	1.00
29_Q	114_T	1.179	1.00
39_I	115_M	1.172	1.00
89_K	92_M	1.167	1.00
22_Q	47_D	1.165	1.00
176_T	179_A	1.156	1.00
145_K	148_F	1.155	1.00
179_A	182_I	1.149	1.00
84_G	195_A	1.147	1.00
138_G	141_D	1.143	1.00
25_F	29_Q	1.142	1.00
162_G	166_L	1.132	1.00
71_L	75_G	1.127	1.00
22_Q	118_V	1.127	1.00
192_W	196_L	1.127	1.00
16_I	156_S	1.125	1.00
159_W	163_L	1.122	1.00
178_K	182_I	1.120	1.00
22_Q	156_S	1.102	1.00
110_K	113_A	1.095	1.00
188_G	192_W	1.089	1.00
169_W	172_P	1.087	1.00
47_D	125_V	1.080	1.00
23_N	160_F	1.080	1.00
26_V	160_F	1.068	1.00
178_K	181_R	1.063	1.00
52_C	56_F	1.062	1.00
42_L	112_I	1.052	1.00
4_Y	7_Q	1.050	1.00
6_F	10_A	1.047	1.00
90_T	184_N	1.043	1.00
44_A	157_F	1.024	1.00
5_Y	153_I	1.009	1.00
37_I	161_F	1.008	1.00
24_A	187_V	1.007	1.00
144_P	148_F	1.001	1.00
110_K	114_T	0.996	1.00
24_A	28_N	0.996	1.00
31_I	167_A	0.989	1.00
7_Q	10_A	0.988	1.00
7_Q	11_L	0.981	1.00
34_Q	108_R	0.979	1.00
79_F	82_W	0.978	1.00
193_F	197_Q	0.975	1.00
47_D	50_L	0.968	1.00
144_P	149_A	0.953	1.00
49_V	120_W	0.948	1.00
26_V	164_A	0.947	1.00
50_L	120_W	0.933	1.00
9_L	13_A	0.931	1.00
34_Q	38_M	0.907	1.00
186_V	189_C	0.896	1.00
106_Q	110_K	0.894	1.00
157_F	161_F	0.887	1.00
13_A	155_A	0.874	1.00
22_Q	160_F	0.868	1.00
50_L	126_Y	0.866	1.00
57_G	64_Q	0.864	1.00
5_Y	154_S	0.861	1.00
117_A	121_L	0.852	1.00
92_M	95_N	0.848	1.00
51_I	129_T	0.842	1.00
28_N	32_R	0.841	1.00
57_G	62_L	0.835	1.00
175_R	179_A	0.835	1.00
185_L	189_C	0.835	1.00
121_L	130_F	0.834	1.00
192_W	195_A	0.834	1.00
160_F	163_L	0.834	1.00
161_F	165_L	0.834	1.00
43_C	47_D	0.829	1.00
169_W	173_R	0.828	1.00
12_G	16_I	0.824	1.00
5_Y	9_L	0.821	1.00
86_G	90_T	0.817	1.00
78_A	81_L	0.816	1.00
23_N	159_W	0.815	1.00
42_L	116_L	0.814	1.00
45_I	116_L	0.809	1.00
23_N	27_M	0.809	1.00
50_L	130_F	0.805	1.00
111_I	114_T	0.804	1.00
46_S	116_L	0.803	1.00
11_L	14_A	0.799	1.00
37_I	164_A	0.795	1.00
50_L	119_T	0.795	1.00
88_F	192_W	0.792	1.00
131_V	135_S	0.790	1.00
150_L	153_I	0.789	1.00
62_L	65_S	0.786	1.00
10_A	14_A	0.772	1.00
180_Q	184_N	0.768	1.00
89_K	93_S	0.766	1.00
45_I	49_V	0.764	1.00
19_L	124_H	0.762	1.00
65_S	69_L	0.759	1.00
173_R	179_A	0.758	1.00
65_S	68_L	0.755	1.00
85_F	192_W	0.751	1.00
105_K	109_W	0.745	1.00
38_M	111_I	0.741	1.00
16_I	160_F	0.735	1.00
144_P	151_G	0.733	1.00
5_Y	151_G	0.732	1.00
75_G	78_A	0.731	1.00
197_Q	200_R	0.727	1.00
40_A	44_A	0.726	1.00
37_I	40_A	0.725	1.00
75_G	121_L	0.724	1.00
26_V	39_I	0.720	1.00
44_A	156_S	0.718	1.00
29_Q	32_R	0.718	1.00
40_A	161_F	0.717	1.00
16_I	23_N	0.717	1.00
166_L	170_L	0.706	1.00
84_G	88_F	0.705	1.00
71_L	74_W	0.704	1.00
27_M	163_L	0.703	1.00
68_L	71_L	0.701	1.00
50_L	125_V	0.696	1.00
59_S	63_M	0.695	1.00
82_W	85_F	0.694	1.00
147_W	151_G	0.693	1.00
166_L	169_W	0.691	1.00
129_T	156_S	0.689	1.00
30_G	167_A	0.685	1.00
173_R	176_T	0.683	1.00
39_I	111_I	0.682	1.00
8_G	134_G	0.681	1.00
159_W	162_G	0.679	1.00
128_D	132_V	0.679	1.00
23_N	118_V	0.677	1.00
46_S	119_T	0.675	1.00
196_L	200_R	0.666	1.00
145_K	150_L	0.664	1.00
50_L	54_G	0.661	1.00
26_V	43_C	0.661	1.00
14_A	18_P	0.659	1.00
54_G	59_S	0.659	1.00
173_R	177_A	0.658	1.00
16_I	47_D	0.652	1.00
47_D	156_S	0.651	1.00
50_L	59_S	0.650	1.00
22_Q	125_V	0.649	1.00
77_V	81_L	0.647	1.00
76_G	127_L	0.643	1.00
142_V	145_K	0.639	1.00
56_F	60_A	0.631	1.00
13_A	17_L	0.630	1.00
16_I	159_W	0.629	1.00
47_D	129_T	0.628	1.00
179_A	183_I	0.627	1.00
141_D	145_K	0.624	1.00
35_Y	108_R	0.624	1.00
92_M	181_R	0.622	1.00
11_L	15_M	0.621	1.00
21_P	122_N	0.614	1.00
18_P	23_N	0.614	1.00
194_I	197_Q	0.612	1.00
54_G	126_Y	0.612	1.00
108_R	112_I	0.606	1.00
158_L	162_G	0.604	1.00
51_I	160_F	0.604	1.00
91_A	94_S	0.604	1.00
119_T	125_V	0.600	1.00
47_D	160_F	0.599	1.00
81_L	199_A	0.598	1.00
35_Y	38_M	0.596	1.00
6_F	9_L	0.593	1.00
33_R	161_F	0.592	1.00
154_S	158_L	0.588	1.00
43_C	119_T	0.586	1.00
8_G	136_L	0.586	1.00
60_A	63_M	0.586	1.00
87_A	188_G	0.578	1.00
18_P	184_N	0.577	1.00
129_T	160_F	0.577	1.00
15_M	132_V	0.576	1.00
149_A	153_I	0.576	1.00
163_L	167_A	0.574	1.00
48_L	52_C	0.571	1.00
160_F	164_A	0.571	1.00
183_I	187_V	0.570	1.00
165_L	169_W	0.570	1.00
186_V	190_V	0.569	1.00
102_E	105_K	0.568	1.00
126_Y	130_F	0.566	1.00
33_R	169_W	0.563	1.00
88_F	189_C	0.562	1.00
21_P	124_H	0.556	1.00
39_I	118_V	0.553	1.00
44_A	160_F	0.552	1.00
66_P	70_A	0.551	1.00
78_A	82_W	0.548	0.99
125_V	156_S	0.548	0.99
174_L	179_A	0.547	0.99
33_R	168_A	0.545	0.99
111_I	115_M	0.545	0.99
162_G	165_L	0.545	0.99
167_A	170_L	0.538	0.99
172_P	175_R	0.538	0.99
65_S	70_A	0.538	0.99
50_L	115_M	0.536	0.99
21_P	87_A	0.536	0.99
138_G	146_R	0.534	0.99
28_N	184_N	0.533	0.99
49_V	52_C	0.533	0.99
114_T	118_V	0.533	0.99
170_L	174_L	0.531	0.99
15_M	125_V	0.523	0.99
86_G	114_T	0.522	0.99
87_A	185_L	0.522	0.99
22_Q	26_V	0.521	0.99
44_A	47_D	0.521	0.99
69_L	79_F	0.520	0.99
9_L	12_G	0.518	0.99
43_C	125_V	0.514	0.99
145_K	152_T	0.513	0.99
33_R	165_L	0.512	0.99
142_V	147_W	0.508	0.99
115_M	128_D	0.505	0.99
18_P	160_F	0.503	0.99
54_G	129_T	0.502	0.99
35_Y	107_G	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2cfqA	1	0.9147	18.2	0.936	Contact Map
3o7qA	1	0.9289	15.7	0.938	Contact Map
1pw4A	1	0.4882	8	0.946	Contact Map
4x5mA	2	0.4408	7.8	0.946	Contact Map
3wdoA	1	0.8863	7.6	0.946	Contact Map
4w6vA	1	0.455	7	0.947	Contact Map
4pypA	1	0.9479	6.7	0.948	Contact Map
3giaA	1	0.4455	6.5	0.948	Contact Map
2gfpA	2	0.9384	6	0.949	Contact Map
4xnjA	1	0.9384	5.5	0.95	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0081 seconds.