FUCK - ECOLI - GREMLIN Contacts

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FUCK - L-fuculokinase

UniProt:	P11553	Sequences: MLSGYIAGAIMKQEVILVLDCGATNVRAIAVNRQGKIVARASTPNASDIAMENNTWHQWSLDAILQRFADCCRQINSELTECHIRGIAVTTFGVDGALVDKQGNLLYPIISWKCPRTAAVMDNIERLISAQRLQAISGVGAFSFNTLYKLVWLKENHPQLLERAHAWLFISSLINHRLTGEFTTDITMAGTSQMLDIQQRDFSPQILQATGIPRRLFPRLVEAGEQIGTLQNSAAAMLGLPVGIPVISAGHDTQFALFGAGAEQNEPVLSSGTWEILMVRSAQVDTSLLSQYAGSTCELDSQAGLYNPGMQWLASGVLEWVRKLFWTAETPWQMLIEEARLIAPGADGVKMQCDLLSCQNAGWQGVTLNTTRGHFYRAALEGLTAQLQRNLQMLEKIGHFKASELLLVGGGSRNTLWNQIKANMLDIPVKVLDDAETTVAGAALFGWYGVGEFNSPEEARAQIHYQYRYFYPQTEPEFIEEV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10350
Length:	482 (453)
Sequences:	12530 (8484)
Seq/√Len:	398.6

ECOLI - FUCK LYXK ARAB LSRK XYLB RHAB GLPK YGCE
BACSU - GNTK XYLB ARAB YOAC GLPK RHAB
HALSA - GLPK
SULSO - GLPK1 GLPK2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
204_P	214_R	4.155	1.00
120_V	155_E	3.902	1.00
32_N	36_K	3.501	1.00
28_A	71_C	3.353	1.00
123_N	155_E	3.287	1.00
388_Q	392_Q	3.166	1.00
196_D	199_Q	2.931	1.00
136_I	203_S	2.856	1.00
395_E	427_I	2.852	1.00
43_T	70_D	2.827	1.00
419_Q	423_N	2.817	1.00
106_L	160_L	2.795	1.00
428_P	471_Y	2.788	1.00
363_W	375_F	2.778	1.00
415_T	468_R	2.722	1.00
195_L	220_L	2.702	1.00
41_A	74_Q	2.682	1.00
454_N	458_E	2.645	1.00
50_A	108_P	2.623	1.00
43_T	74_Q	2.606	1.00
404_E	430_K	2.593	1.00
65_L	177_R	2.562	1.00
222_E	225_E	2.543	1.00
101_K	165_H	2.526	1.00
455_S	458_E	2.522	1.00
107_Y	157_H	2.491	1.00
30_A	75_I	2.451	1.00
62_D	177_R	2.428	1.00
100_D	163_R	2.425	1.00
201_D	214_R	2.351	1.00
207_L	214_R	2.325	1.00
196_D	203_S	2.292	1.00
331_P	334_M	2.255	1.00
166_A	182_F	2.255	1.00
204_P	208_Q	2.240	1.00
181_E	219_R	2.197	1.00
250_G	255_F	2.184	1.00
29_I	439_V	2.145	1.00
19_L	68_F	2.124	1.00
175_N	249_A	2.118	1.00
14_E	85_R	2.089	1.00
473_Q	476_P	2.082	1.00
317_V	379_A	2.072	1.00
62_D	104_N	2.026	1.00
123_N	127_L	2.009	1.00
132_R	135_A	2.007	1.00
25_N	42_S	2.006	1.00
231_Q	234_A	1.999	1.00
275_E	314_A	1.987	1.00
371_T	374_H	1.980	1.00
407_L	418_N	1.952	1.00
53_N	56_W	1.938	1.00
17_L	72_C	1.934	1.00
46_A	63_A	1.919	1.00
232_N	242_V	1.915	1.00
16_I	447_W	1.905	1.00
395_E	401_K	1.902	1.00
347_D	374_H	1.895	1.00
21_C	26_V	1.887	1.00
179_T	246_V	1.855	1.00
15_V	38_V	1.820	1.00
17_L	28_A	1.818	1.00
183_T	221_V	1.802	1.00
221_V	225_E	1.795	1.00
151_V	155_E	1.790	1.00
342_I	374_H	1.788	1.00
136_I	205_Q	1.782	1.00
247_I	449_G	1.767	1.00
132_R	136_I	1.763	1.00
321_V	379_A	1.734	1.00
15_V	30_A	1.729	1.00
226_Q	229_T	1.726	1.00
98_L	153_L	1.715	1.00
103_G	176_H	1.715	1.00
100_D	104_N	1.713	1.00
132_R	205_Q	1.695	1.00
122_D	126_R	1.686	1.00
338_E	373_G	1.680	1.00
226_Q	247_I	1.679	1.00
333_Q	336_I	1.665	1.00
334_M	338_E	1.637	1.00
332_W	335_L	1.626	1.00
360_N	367_T	1.603	1.00
119_A	123_N	1.597	1.00
16_I	452_E	1.596	1.00
14_E	83_H	1.591	1.00
266_E	404_E	1.590	1.00
423_N	473_Q	1.571	1.00
428_P	469_Y	1.569	1.00
125_E	130_A	1.564	1.00
430_K	469_Y	1.562	1.00
319_E	323_K	1.562	1.00
264_Q	282_A	1.548	1.00
198_Q	284_V	1.541	1.00
97_A	170_I	1.537	1.00
98_L	216_L	1.518	1.00
377_R	381_E	1.518	1.00
241_P	244_I	1.517	1.00
392_Q	395_E	1.508	1.00
159_Q	162_E	1.507	1.00
60_S	63_A	1.495	1.00
41_A	75_I	1.488	1.00
175_N	227_I	1.476	1.00
334_M	337_E	1.472	1.00
41_A	71_C	1.431	1.00
447_W	453_F	1.427	1.00
62_D	66_Q	1.423	1.00
65_L	69_A	1.417	1.00
333_Q	337_E	1.410	1.00
131_Q	135_A	1.409	1.00
416_L	420_I	1.402	1.00
179_T	228_G	1.395	1.00
213_P	216_L	1.392	1.00
415_T	470_F	1.363	1.00
33_R	452_E	1.357	1.00
99_V	168_L	1.356	1.00
267_P	402_A	1.352	1.00
271_S	421_K	1.343	1.00
86_G	446_G	1.340	1.00
152_W	156_N	1.337	1.00
384_T	420_I	1.336	1.00
39_A	75_I	1.336	1.00
173_L	177_R	1.333	1.00
415_T	431_V	1.329	1.00
229_T	243_G	1.328	1.00
423_N	476_P	1.319	1.00
118_A	122_D	1.308	1.00
384_T	421_K	1.308	1.00
186_I	200_R	1.307	1.00
93_G	251_H	1.302	1.00
404_E	428_P	1.297	1.00
26_V	68_F	1.297	1.00
207_L	217_F	1.295	1.00
101_K	166_A	1.293	1.00
384_T	424_M	1.292	1.00
132_R	209_A	1.289	1.00
221_V	227_I	1.289	1.00
19_L	72_C	1.287	1.00
311_Q	386_Q	1.279	1.00
120_V	151_V	1.277	1.00
30_A	79_L	1.268	1.00
154_K	161_L	1.264	1.00
226_Q	245_P	1.258	1.00
269_L	421_K	1.253	1.00
175_N	183_T	1.246	1.00
66_Q	70_D	1.240	1.00
50_A	63_A	1.231	1.00
147_L	210_T	1.225	1.00
26_V	67_R	1.224	1.00
388_Q	425_L	1.223	1.00
80_T	83_H	1.216	1.00
250_G	445_F	1.214	1.00
95_D	109_I	1.208	1.00
336_I	340_R	1.199	1.00
157_H	160_L	1.196	1.00
420_I	424_M	1.196	1.00
205_Q	208_Q	1.190	1.00
19_L	28_A	1.188	1.00
418_N	470_F	1.184	1.00
70_D	74_Q	1.182	1.00
263_E	266_E	1.179	1.00
103_G	182_F	1.173	1.00
168_L	182_F	1.164	1.00
31_V	37_I	1.164	1.00
133_L	141_A	1.161	1.00
263_E	460_R	1.156	1.00
183_T	227_I	1.150	1.00
68_F	174_I	1.150	1.00
58_Q	108_P	1.150	1.00
339_A	416_L	1.149	1.00
313_L	317_V	1.147	1.00
335_L	338_E	1.146	1.00
15_V	83_H	1.138	1.00
338_E	372_R	1.137	1.00
127_L	209_A	1.134	1.00
186_I	220_L	1.128	1.00
161_L	164_A	1.124	1.00
60_S	108_P	1.124	1.00
342_I	346_A	1.123	1.00
98_L	164_A	1.123	1.00
431_V	470_F	1.122	1.00
336_I	339_A	1.121	1.00
413_R	435_A	1.115	1.00
14_E	33_R	1.114	1.00
325_F	375_F	1.113	1.00
119_A	122_D	1.113	1.00
121_M	141_A	1.105	1.00
46_A	50_A	1.105	1.00
385_A	424_M	1.102	1.00
164_A	216_L	1.100	1.00
16_I	450_V	1.097	1.00
61_L	97_A	1.096	1.00
122_D	125_E	1.095	1.00
226_Q	449_G	1.083	1.00
313_L	316_G	1.083	1.00
406_L	430_K	1.081	1.00
64_I	170_I	1.079	1.00
31_V	443_A	1.072	1.00
159_Q	163_R	1.067	1.00
107_Y	160_L	1.066	1.00
444_L	459_A	1.063	1.00
330_T	334_M	1.058	1.00
266_E	406_L	1.054	1.00
116_R	152_W	1.054	1.00
377_R	416_L	1.054	1.00
448_Y	459_A	1.053	1.00
120_V	156_N	1.050	1.00
263_E	457_E	1.050	1.00
265_N	403_S	1.049	1.00
186_I	195_L	1.047	1.00
366_V	370_T	1.044	1.00
86_G	450_V	1.043	1.00
89_V	175_N	1.042	1.00
207_L	212_I	1.040	1.00
361_A	366_V	1.040	1.00
370_T	374_H	1.037	1.00
98_L	150_L	1.037	1.00
331_P	336_I	1.033	1.00
87_I	244_I	1.033	1.00
45_N	67_R	1.030	1.00
388_Q	424_M	1.029	1.00
391_L	425_L	1.027	1.00
86_G	247_I	1.025	1.00
298_E	303_A	1.024	1.00
57_H	113_K	1.017	1.00
28_A	75_I	1.015	1.00
39_A	77_S	1.014	1.00
433_D	464_H	1.009	1.00
458_E	461_A	1.003	1.00
63_A	66_Q	0.997	1.00
135_A	286_T	0.997	1.00
383_L	411_G	0.994	1.00
15_V	79_L	0.991	1.00
433_D	466_Q	0.990	1.00
123_N	126_R	0.989	1.00
447_W	452_E	0.985	1.00
17_L	30_A	0.984	1.00
147_L	193_Q	0.982	1.00
68_F	72_C	0.976	1.00
247_I	450_V	0.975	1.00
150_L	167_W	0.975	1.00
69_A	73_R	0.972	1.00
133_L	193_Q	0.970	1.00
326_W	372_R	0.969	1.00
337_E	340_R	0.967	1.00
90_T	438_T	0.967	1.00
332_W	336_I	0.966	1.00
229_T	245_P	0.965	1.00
200_R	222_E	0.964	1.00
268_V	408_V	0.962	1.00
338_E	341_L	0.962	1.00
184_T	189_A	0.961	1.00
176_H	182_F	0.961	1.00
283_Q	302_Q	0.961	1.00
335_L	376_Y	0.956	1.00
351_M	363_W	0.955	1.00
16_I	86_G	0.952	1.00
282_A	304_G	0.950	1.00
267_P	279_V	0.949	1.00
37_I	40_R	0.944	1.00
135_A	198_Q	0.943	1.00
195_L	199_Q	0.936	1.00
411_G	417_W	0.935	1.00
198_Q	286_T	0.933	1.00
165_H	215_R	0.933	1.00
31_V	440_A	0.932	1.00
120_V	123_N	0.928	1.00
356_L	359_Q	0.924	1.00
17_L	84_I	0.922	1.00
444_L	463_I	0.922	1.00
104_N	177_R	0.919	1.00
332_W	338_E	0.918	1.00
158_P	162_E	0.917	1.00
98_L	167_W	0.916	1.00
343_A	346_A	0.915	1.00
32_N	38_V	0.914	1.00
30_A	84_I	0.913	1.00
263_E	403_S	0.906	1.00
453_F	459_A	0.905	1.00
404_E	469_Y	0.904	1.00
164_A	167_W	0.904	1.00
412_S	435_A	0.903	1.00
129_S	209_A	0.903	1.00
21_C	174_I	0.903	1.00
82_C	241_P	0.899	1.00
277_L	391_L	0.895	1.00
172_S	184_T	0.895	1.00
107_Y	153_L	0.890	1.00
160_L	163_R	0.888	1.00
433_D	465_Y	0.886	1.00
96_G	167_W	0.885	1.00
180_G	231_Q	0.883	1.00
85_R	450_V	0.883	1.00
345_G	348_G	0.880	1.00
425_L	428_P	0.879	1.00
123_N	151_V	0.878	1.00
153_L	160_L	0.875	1.00
275_E	387_L	0.874	1.00
89_V	174_I	0.872	1.00
88_A	247_I	0.872	1.00
337_E	341_L	0.871	1.00
186_I	222_E	0.870	1.00
151_V	154_K	0.868	1.00
189_A	202_F	0.867	1.00
52_E	56_W	0.861	1.00
331_P	338_E	0.860	1.00
89_V	178_L	0.856	1.00
405_L	425_L	0.855	1.00
186_I	298_E	0.855	1.00
363_W	379_A	0.849	1.00
94_V	191_T	0.846	1.00
202_F	217_F	0.844	1.00
183_T	219_R	0.843	1.00
280_R	304_G	0.841	1.00
121_M	148_Y	0.839	1.00
256_A	408_V	0.837	1.00
453_F	462_Q	0.835	1.00
354_D	359_Q	0.834	1.00
84_I	244_I	0.832	1.00
221_V	248_S	0.832	1.00
392_Q	396_K	0.831	1.00
201_D	219_R	0.829	1.00
366_V	375_F	0.829	1.00
341_L	373_G	0.827	1.00
147_L	194_M	0.827	1.00
351_M	355_L	0.826	1.00
448_Y	455_S	0.826	1.00
169_F	192_S	0.823	1.00
195_L	200_R	0.821	1.00
44_P	319_E	0.817	1.00
21_C	68_F	0.816	1.00
129_S	132_R	0.815	1.00
232_N	243_G	0.814	1.00
229_T	242_V	0.814	1.00
391_L	395_E	0.814	1.00
43_T	71_C	0.813	1.00
45_N	59_W	0.811	1.00
119_A	156_N	0.810	1.00
344_P	349_V	0.809	1.00
316_G	319_E	0.808	1.00
448_Y	456_P	0.807	1.00
336_I	414_N	0.807	1.00
40_R	436_E	0.806	1.00
201_D	204_P	0.805	1.00
289_L	396_K	0.804	1.00
279_V	394_L	0.793	1.00
99_V	103_G	0.790	1.00
287_S	397_I	0.789	1.00
106_L	163_R	0.789	1.00
184_T	218_P	0.786	1.00
380_L	420_I	0.786	1.00
85_R	452_E	0.785	1.00
200_R	303_A	0.784	1.00
115_P	142_F	0.781	1.00
125_E	141_A	0.780	1.00
61_L	108_P	0.779	1.00
150_L	194_M	0.779	1.00
260_A	408_V	0.778	1.00
393_M	396_K	0.778	1.00
93_G	188_M	0.777	1.00
76_N	80_T	0.776	1.00
269_L	275_E	0.775	1.00
342_I	345_G	0.774	1.00
263_E	461_A	0.773	1.00
380_L	414_N	0.769	1.00
93_G	308_P	0.767	1.00
384_T	417_W	0.766	1.00
345_G	349_V	0.766	1.00
31_V	434_D	0.766	1.00
342_I	347_D	0.765	1.00
208_Q	214_R	0.760	1.00
426_D	474_T	0.760	1.00
121_M	143_S	0.759	1.00
253_T	276_I	0.759	1.00
343_A	347_D	0.758	1.00
205_Q	209_A	0.757	1.00
171_S	249_A	0.754	1.00
289_L	397_I	0.752	1.00
184_T	220_L	0.751	1.00
269_L	387_L	0.751	1.00
230_L	244_I	0.751	1.00
99_V	182_F	0.746	1.00
87_I	230_L	0.746	1.00
329_E	334_M	0.746	1.00
151_V	211_G	0.745	1.00
69_A	234_A	0.741	1.00
407_L	421_K	0.740	1.00
63_A	67_R	0.740	1.00
458_E	462_Q	0.740	1.00
331_P	335_L	0.739	1.00
136_I	196_D	0.739	1.00
18_V	88_A	0.736	1.00
281_S	285_D	0.735	1.00
260_A	268_V	0.733	1.00
335_L	339_A	0.731	1.00
62_D	173_L	0.730	1.00
412_S	418_N	0.730	1.00
321_V	375_F	0.726	1.00
112_W	274_W	0.725	1.00
360_N	364_Q	0.725	1.00
230_L	240_L	0.725	1.00
276_I	310_M	0.725	1.00
69_A	177_R	0.725	1.00
351_M	378_A	0.723	1.00
119_A	155_E	0.722	1.00
23_A	111_S	0.722	1.00
256_A	438_T	0.720	1.00
381_E	420_I	0.718	1.00
137_S	206_I	0.718	1.00
79_L	83_H	0.718	1.00
86_G	245_P	0.716	1.00
299_L	302_Q	0.715	1.00
407_L	429_V	0.715	1.00
21_C	67_R	0.715	1.00
133_L	206_I	0.714	1.00
100_D	106_L	0.713	1.00
166_A	216_L	0.711	1.00
240_L	243_G	0.711	1.00
187_T	250_G	0.711	1.00
101_K	163_R	0.710	1.00
459_A	463_I	0.710	1.00
262_A	268_V	0.706	1.00
100_D	165_H	0.703	1.00
33_R	85_R	0.703	1.00
66_Q	69_A	0.702	1.00
43_T	67_R	0.700	1.00
321_V	325_F	0.699	1.00
309_G	390_N	0.698	1.00
175_N	179_T	0.698	1.00
262_A	266_E	0.697	1.00
393_M	397_I	0.697	1.00
314_A	383_L	0.697	1.00
240_L	244_I	0.696	1.00
471_Y	474_T	0.695	1.00
252_D	273_T	0.693	1.00
98_L	106_L	0.693	1.00
70_D	73_R	0.692	1.00
330_T	333_Q	0.691	1.00
267_P	405_L	0.690	1.00
419_Q	473_Q	0.689	1.00
62_D	105_L	0.689	1.00
457_E	460_R	0.689	1.00
196_D	201_D	0.688	1.00
58_Q	116_R	0.688	1.00
173_L	176_H	0.687	1.00
34_Q	462_Q	0.687	1.00
99_V	166_A	0.686	1.00
200_R	298_E	0.686	1.00
444_L	462_Q	0.685	0.99
269_L	405_L	0.685	0.99
103_G	165_H	0.683	0.99
405_L	427_I	0.683	0.99
343_A	349_V	0.683	0.99
403_S	427_I	0.681	0.99
342_I	363_W	0.679	0.99
234_A	243_G	0.678	0.99
203_S	206_I	0.678	0.99
465_Y	469_Y	0.677	0.99
381_E	385_A	0.676	0.99
405_L	429_V	0.676	0.99
407_L	431_V	0.675	0.99
124_I	210_T	0.672	0.99
321_V	376_Y	0.671	0.99
39_A	76_N	0.667	0.99
29_I	37_I	0.667	0.99
345_G	350_K	0.665	0.99
65_L	234_A	0.662	0.99
242_V	245_P	0.659	0.99
459_A	462_Q	0.658	0.99
279_V	398_G	0.655	0.99
69_A	72_C	0.655	0.99
91_T	188_M	0.653	0.99
404_E	427_I	0.651	0.99
319_E	322_R	0.649	0.99
99_V	173_L	0.649	0.99
44_P	322_R	0.648	0.99
223_A	249_A	0.647	0.99
187_T	297_C	0.646	0.99
385_A	388_Q	0.642	0.99
110_I	116_R	0.641	0.99
26_V	45_N	0.640	0.99
172_S	182_F	0.639	0.99
16_I	85_R	0.639	0.99
14_E	452_E	0.639	0.99
349_V	370_T	0.639	0.99
72_C	75_I	0.638	0.99
444_L	448_Y	0.638	0.99
103_G	166_A	0.638	0.99
336_I	415_T	0.636	0.99
331_P	339_A	0.636	0.99
348_G	351_M	0.633	0.99
97_A	109_I	0.631	0.99
99_V	176_H	0.631	0.99
275_E	421_K	0.630	0.99
166_A	176_H	0.627	0.99
463_I	466_Q	0.627	0.99
343_A	350_K	0.626	0.99
455_S	461_A	0.626	0.99
229_T	232_N	0.626	0.99
377_R	420_I	0.626	0.99
141_A	193_Q	0.626	0.99
332_W	339_A	0.624	0.99
419_Q	422_A	0.623	0.99
402_A	427_I	0.622	0.99
344_P	350_K	0.622	0.99
336_I	380_L	0.621	0.99
447_W	451_G	0.619	0.99
68_F	71_C	0.619	0.99
117_T	148_Y	0.618	0.99
187_T	223_A	0.617	0.99
346_A	350_K	0.617	0.99
78_E	81_E	0.616	0.99
171_S	188_M	0.615	0.99
128_I	206_I	0.615	0.99
426_D	476_P	0.614	0.99
261_G	463_I	0.614	0.99
194_M	217_F	0.614	0.99
278_M	306_Y	0.612	0.99
414_N	417_W	0.612	0.99
151_V	161_L	0.611	0.99
226_Q	450_V	0.610	0.99
150_L	216_L	0.610	0.99
92_F	112_W	0.610	0.99
251_H	254_Q	0.609	0.99
96_G	146_T	0.607	0.99
62_D	108_P	0.607	0.99
329_E	372_R	0.604	0.99
97_A	105_L	0.604	0.99
341_L	344_P	0.603	0.99
453_F	456_P	0.603	0.99
311_Q	390_N	0.603	0.99
326_W	335_L	0.600	0.99
61_L	109_I	0.599	0.99
91_T	170_I	0.599	0.99
143_S	357_S	0.598	0.99
457_E	461_A	0.598	0.99
284_V	305_L	0.597	0.99
37_I	434_D	0.597	0.99
31_V	439_V	0.597	0.99
261_G	460_R	0.595	0.99
222_E	298_E	0.594	0.99
148_Y	193_Q	0.594	0.99
151_V	210_T	0.593	0.99
340_R	416_L	0.592	0.99
87_I	246_V	0.591	0.99
124_I	148_Y	0.591	0.99
275_E	311_Q	0.591	0.99
154_K	211_G	0.591	0.99
448_Y	453_F	0.591	0.99
335_L	373_G	0.589	0.98
460_R	464_H	0.587	0.98
434_D	440_A	0.587	0.98
16_I	453_F	0.586	0.98
374_H	377_R	0.586	0.98
415_T	419_Q	0.586	0.98
145_N	191_T	0.586	0.98
419_Q	470_F	0.584	0.98
206_I	210_T	0.584	0.98
344_P	347_D	0.584	0.98
253_T	270_S	0.584	0.98
110_I	153_L	0.583	0.98
131_Q	134_Q	0.583	0.98
277_L	390_N	0.582	0.98
266_E	403_S	0.582	0.98
81_E	84_I	0.582	0.98
315_S	319_E	0.582	0.98
118_A	143_S	0.581	0.98
76_N	81_E	0.581	0.98
161_L	165_H	0.580	0.98
227_I	248_S	0.578	0.98
266_E	460_R	0.577	0.98
257_L	278_M	0.576	0.98
219_R	225_E	0.576	0.98
338_E	376_Y	0.576	0.98
284_V	293_A	0.575	0.98
351_M	382_G	0.574	0.98
320_W	323_K	0.573	0.98
181_E	221_V	0.573	0.98
245_P	450_V	0.572	0.98
269_L	277_L	0.572	0.98
51_M	57_H	0.570	0.98
318_L	336_I	0.569	0.98
139_V	145_N	0.569	0.98
271_S	407_L	0.567	0.98
327_T	372_R	0.566	0.98
208_Q	213_P	0.564	0.98
15_V	82_C	0.563	0.98
212_I	217_F	0.563	0.98
259_G	437_T	0.562	0.98
383_L	417_W	0.562	0.98
339_A	377_R	0.562	0.98
428_P	472_P	0.561	0.98
420_I	474_T	0.559	0.98
168_L	176_H	0.558	0.98
192_S	202_F	0.557	0.98
234_A	240_L	0.556	0.98
67_R	70_D	0.556	0.98
208_Q	211_G	0.554	0.98
93_G	191_T	0.554	0.98
345_G	377_R	0.554	0.98
84_I	240_L	0.553	0.98
24_T	27_R	0.553	0.98
181_E	229_T	0.552	0.98
116_R	156_N	0.550	0.98
340_R	415_T	0.550	0.98
281_S	307_N	0.549	0.98
161_L	211_G	0.549	0.98
59_W	111_S	0.548	0.98
95_D	111_S	0.548	0.98
95_D	170_I	0.547	0.98
62_D	65_L	0.546	0.98
58_Q	107_Y	0.545	0.98
353_C	359_Q	0.545	0.98
317_V	342_I	0.544	0.97
448_Y	451_G	0.544	0.97
23_A	112_W	0.539	0.97
440_A	444_L	0.539	0.97
252_D	410_G	0.539	0.97
257_L	296_T	0.538	0.97
224_G	449_G	0.538	0.97
56_W	116_R	0.537	0.97
322_R	332_W	0.535	0.97
57_H	111_S	0.534	0.97
98_L	107_Y	0.531	0.97
339_A	376_Y	0.531	0.97
230_L	241_P	0.530	0.97
385_A	420_I	0.529	0.97
222_E	302_Q	0.528	0.97
161_L	213_P	0.527	0.97
387_L	421_K	0.527	0.97
60_S	66_Q	0.526	0.97
279_V	402_A	0.526	0.97
106_L	164_A	0.525	0.97
43_T	46_A	0.523	0.97
105_L	108_P	0.523	0.97
344_P	348_G	0.522	0.97
430_K	465_Y	0.522	0.97
56_W	110_I	0.522	0.97
18_V	439_V	0.522	0.97
92_F	109_I	0.521	0.97
125_E	129_S	0.520	0.97
319_E	332_W	0.520	0.97
386_Q	389_R	0.520	0.97
137_S	193_Q	0.519	0.97
77_S	81_E	0.519	0.97
29_I	40_R	0.518	0.97
462_Q	465_Y	0.516	0.97
294_G	306_Y	0.515	0.97
421_K	425_L	0.515	0.97
64_I	109_I	0.515	0.97
422_A	429_V	0.514	0.96
460_R	463_I	0.513	0.96
412_S	431_V	0.513	0.96
456_P	460_R	0.512	0.96
347_D	370_T	0.512	0.96
346_A	349_V	0.510	0.96
309_G	312_W	0.510	0.96
403_S	428_P	0.510	0.96
231_Q	243_G	0.510	0.96
271_S	411_G	0.510	0.96
223_A	250_G	0.509	0.96
94_V	112_W	0.509	0.96
104_N	163_R	0.509	0.96
96_G	153_L	0.508	0.96
277_L	387_L	0.508	0.96
347_D	350_K	0.507	0.96
59_W	92_F	0.506	0.96
258_F	444_L	0.506	0.96
273_T	410_G	0.506	0.96
90_T	442_A	0.505	0.96
41_A	76_N	0.505	0.96
29_I	440_A	0.505	0.96
185_D	248_S	0.505	0.96
99_V	165_H	0.503	0.96
270_S	408_V	0.503	0.96
133_L	210_T	0.503	0.96
198_Q	201_D	0.502	0.96
355_L	359_Q	0.501	0.96
224_G	448_Y	0.500	0.96
234_A	239_G	0.500	0.96

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3ll3A	2	0.9606	100	0.137	Contact Map
2itmA	2	0.9419	100	0.165	Contact Map
3hz6A	1	0.9544	100	0.168	Contact Map
3qdkA	2	0.9647	100	0.174	Contact Map
3ifrA	2	0.9564	100	0.174	Contact Map
3wxlA	2	0.9668	100	0.18	Contact Map
3ezwA	3	0.9564	100	0.18	Contact Map
2w40A	3	0.9585	100	0.187	Contact Map
4bc3A	1	0.9627	100	0.192	Contact Map
3h3nX	3	0.9544	100	0.193	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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