ENTF - ECOLI - GREMLIN Contacts

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ENTF - Enterobactin synthase component F

UniProt:	P11454	Sequences: MSQHLPLVAAQPGIWMAEKLSELPSAWSVAHYVELTGEVDSPLLARAVVAGLAQADTLRMRFTEDNGEVWQWVDDALTFELPEIIDLRTNIDPHGTAQALMQADLQQDLRVDSGKPLVFHQLIQVADNRWYWYQRYHHLLVDGFSFPAITRQIANIYCTWLRGEPTPASPFTPFADVVEEYQQYRESEAWQRDAAFWAEQRRQLPPPASLSPAPLPGRSASADILRLKLEFTDGEFRQLATQLSGVQRTDLALALAALWLGRLCNRMDYAAGFIFMRRLGSAALTATGPVLNVLPLGIHIAAQETLPELATRLAAQLKKMRRHQRYDAEQIVRDSGRAAGDEPLFGPVLNIKVFDYQLDIPDVQAQTHTLATGPVNDLELALFPDVHGDLSIEILANKQRYDEPTLIQHAERLKMLIAQFAADPALLCGDVDIMLPGEYAQLAQLNATQVEIPETTLSALVAEQAAKTPDAPALADARYLFSYREMREQVVALANLLRERGVKPGDSVAVALPRSVFLTLALHAIVEAGAAWLPLDTGYPDDRLKMMLEDARPSLLITTDDQLPRFSDVPNLTSLCYNAPLTPQGSAPLQLSQPHHTAYIIFTSGSTGRPKGVMVGQTAIVNRLLWMQNHYPLTGEDVVAQKTPCSFDVSVWEFFWPFIAGAKLVMAEPEAHRDPLAMQQFFAEYGVTTTHFVPSMLAAFVASLTPQTARQSCATLKQVFCSGEALPADLCREWQQLTGAPLHNLYGPTEAAVDVSWYPAFGEELAQVRGSSVPIGYPVWNTGLRILDAMMHPVPPGVAGDLYLTGIQLAQGYLGRPDLTASRFIADPFAPGERMYRTGDVARWLDNGAVEYLGRSDDQLKIRGQRIELGEIDRVMQALPDVEQAVTHACVINQAAATGGDARQLVGYLVSQSGLPLDTSALQAQLRETLPPHMVPVVLLQLPQLPLSANGKLDRKALPLPELKAQAPGRAPKAGSETIIAAAFSSLLGCDVQDADADFFALGGHSLLAMKLAAQLSRQVARQVTPGQVMVASTVAKLATIIDAEEDSTRRMGFETILPLREGNGPTLFCFHPASGFAWQFSVLSRYLDPQWSIIGIQSPRPNGPMQTAANLDEVCEAHLATLLEQQPHGPYYLLGYSLGGTLAQGIAARLRARGEQVAFLGLLDTWPPETQNWQEKEANGLDPEVLAEINREREAFLAAQQGSTSTELFTTIEGNYADAVRLLTTAHSVPFDGKATLFVAERTLQEGMSPERAWSPWIAELDIYRQDCAHVDIISPGTFEKIGPIIRATLNR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10264
Length:	1293 (1023)
Sequences:	16900 (14021)
Seq/√Len:	438.4

ECOLI - ENTF
BACSU - PPSE SRFAC PPSC PPSB DHBF PPSD SRFAA SRFAB PKSJ PKSN PPSA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
597_T	614_M	4.963	1.00
879_L	925_Q	4.442	1.00
802_L	842_A	4.329	1.00
507_S	533_L	4.131	1.00
505_G	596_H	3.750	1.00
505_G	811_Q	3.699	1.00
535_L	544_L	3.581	1.00
61_R	74_D	3.473	1.00
616_G	811_Q	3.334	1.00
268_D	297_G	3.298	1.00
550_D	602_F	3.070	1.00
304_E	312_R	3.051	1.00
980_I	1016_L	2.862	1.00
1025_T	1028_Q	2.858	1.00
487_R	527_E	2.847	1.00
786_I	842_A	2.832	1.00
741_P	759_P	2.806	1.00
638_V	663_K	2.706	1.00
983_A	1012_L	2.703	1.00
34_E	129_R	2.695	1.00
843_R	851_E	2.687	1.00
491_V	527_E	2.684	1.00
799_A	853_L	2.676	1.00
496_L	500_R	2.647	1.00
462_A	487_R	2.629	1.00
464_Q	468_T	2.609	1.00
976_S	1043_D	2.606	1.00
970_R	996_D	2.599	1.00
213_A	402_D	2.574	1.00
787_L	803_Y	2.562	1.00
998_D	1001_A	2.551	1.00
756_S	784_L	2.540	1.00
51_G	156_I	2.498	1.00
259_W	416_L	2.495	1.00
502_V	530_A	2.493	1.00
786_I	850_V	2.487	1.00
805_T	835_M	2.466	1.00
394_I	406_L	2.461	1.00
455_T	463_E	2.448	1.00
619_A	752_A	2.445	1.00
487_R	587_A	2.416	1.00
493_L	524_A	2.416	1.00
484_R	488_E	2.412	1.00
306_L	420_F	2.408	1.00
493_L	520_L	2.396	1.00
784_L	804_L	2.392	1.00
695_S	724_E	2.389	1.00
680_Q	684_E	2.376	1.00
263_L	412_R	2.351	1.00
403_E	407_I	2.327	1.00
907_G	939_L	2.300	1.00
816_R	819_L	2.298	1.00
973_K	995_A	2.294	1.00
616_G	619_A	2.261	1.00
996_D	1036_A	2.249	1.00
509_A	553_P	2.242	1.00
986_S	1015_Q	2.242	1.00
464_Q	467_K	2.238	1.00
998_D	1033_S	2.231	1.00
240_A	251_L	2.219	1.00
637_D	688_T	2.216	1.00
193_D	323_H	2.193	1.00
506_D	530_A	2.177	1.00
909_L	939_L	2.172	1.00
691_H	754_D	2.162	1.00
502_V	506_D	2.156	1.00
506_D	554_S	2.147	1.00
597_T	811_Q	2.140	1.00
200_Q	316_Q	2.124	1.00
468_T	471_A	2.121	1.00
975_G	978_T	2.114	1.00
504_P	596_H	2.112	1.00
974_A	1043_D	2.111	1.00
910_V	945_L	2.103	1.00
227_L	392_I	2.101	1.00
1017_S	1023_Q	2.092	1.00
600_I	814_L	2.087	1.00
783_G	827_D	2.078	1.00
862_I	893_N	2.067	1.00
1034_T	1037_K	2.066	1.00
908_Y	959_P	2.062	1.00
491_V	495_N	2.040	1.00
507_S	600_I	2.036	1.00
244_S	307_P	2.035	1.00
783_G	805_T	2.024	1.00
799_A	841_V	2.016	1.00
49_V	53_A	2.006	1.00
622_N	781_N	2.005	1.00
969_G	992_V	1.996	1.00
36_T	129_R	1.991	1.00
995_A	1035_V	1.981	1.00
472_P	480_L	1.976	1.00
256_A	347_P	1.973	1.00
236_F	248_R	1.973	1.00
518_L	645_C	1.966	1.00
382_L	392_I	1.950	1.00
223_D	398_K	1.946	1.00
270_A	295_P	1.938	1.00
875_V	926_L	1.935	1.00
860_L	869_L	1.934	1.00
307_P	425_A	1.929	1.00
412_R	438_E	1.929	1.00
619_A	809_L	1.922	1.00
394_I	410_A	1.917	1.00
637_D	717_K	1.913	1.00
649_V	691_H	1.910	1.00
54_Q	152_Q	1.906	1.00
595_H	618_T	1.885	1.00
546_M	609_R	1.882	1.00
981_A	1035_V	1.882	1.00
257_A	298_I	1.871	1.00
510_V	522_L	1.870	1.00
637_D	662_A	1.868	1.00
983_A	1016_L	1.867	1.00
96_T	99_A	1.857	1.00
7_L	69_V	1.849	1.00
223_D	403_E	1.846	1.00
877_Q	884_Q	1.845	1.00
495_N	588_P	1.840	1.00
51_G	153_I	1.831	1.00
475_A	663_K	1.829	1.00
490_V	527_E	1.827	1.00
237_R	384_P	1.816	1.00
878_A	929_T	1.815	1.00
629_N	780_W	1.812	1.00
117_L	140_L	1.804	1.00
970_R	995_A	1.802	1.00
638_V	687_V	1.801	1.00
994_D	997_A	1.800	1.00
886_V	953_L	1.799	1.00
1007_L	1010_M	1.799	1.00
979_I	1019_Q	1.785	1.00
845_L	851_E	1.772	1.00
668_E	671_A	1.759	1.00
136_Y	141_V	1.756	1.00
908_Y	961_P	1.750	1.00
827_D	833_E	1.748	1.00
546_M	602_F	1.741	1.00
974_A	995_A	1.737	1.00
984_F	1035_V	1.734	1.00
999_F	1004_G	1.732	1.00
256_A	380_L	1.732	1.00
652_W	754_D	1.727	1.00
784_L	802_L	1.726	1.00
151_R	285_T	1.724	1.00
489_Q	517_F	1.723	1.00
225_L	407_I	1.723	1.00
500_R	573_T	1.721	1.00
758_Y	774_P	1.720	1.00
45_A	49_V	1.718	1.00
1012_L	1029_V	1.714	1.00
487_R	491_V	1.711	1.00
906_V	940_L	1.710	1.00
667_A	681_F	1.707	1.00
19_K	64_E	1.696	1.00
487_R	490_V	1.696	1.00
194_A	326_Y	1.691	1.00
595_H	616_G	1.690	1.00
745_L	754_D	1.689	1.00
642_K	693_V	1.677	1.00
1028_Q	1041_I	1.677	1.00
643_T	649_V	1.673	1.00
510_V	521_A	1.672	1.00
457_L	620_I	1.669	1.00
507_S	531_A	1.668	1.00
470_D	484_R	1.666	1.00
462_A	527_E	1.660	1.00
521_A	557_I	1.659	1.00
86_D	124_Q	1.656	1.00
845_L	849_A	1.653	1.00
691_H	745_L	1.653	1.00
255_L	417_I	1.651	1.00
652_W	691_H	1.645	1.00
48_V	120_H	1.639	1.00
758_Y	849_A	1.637	1.00
256_A	349_L	1.635	1.00
623_R	754_D	1.635	1.00
1032_A	1041_I	1.635	1.00
423_D	426_L	1.634	1.00
974_A	978_T	1.632	1.00
665_V	681_F	1.630	1.00
427_L	430_D	1.626	1.00
380_L	394_I	1.622	1.00
481_F	520_L	1.619	1.00
886_V	945_L	1.619	1.00
149_I	287_T	1.617	1.00
671_A	677_A	1.615	1.00
653_E	691_H	1.603	1.00
665_V	687_V	1.601	1.00
268_D	299_H	1.601	1.00
432_D	439_Y	1.601	1.00
60_M	71_Q	1.600	1.00
623_R	652_W	1.600	1.00
539_Y	547_M	1.599	1.00
593_Q	596_H	1.598	1.00
982_A	1019_Q	1.596	1.00
475_A	685_Y	1.595	1.00
272_G	345_F	1.593	1.00
88_R	127_D	1.591	1.00
503_K	506_D	1.589	1.00
204_L	270_A	1.583	1.00
942_L	945_L	1.581	1.00
445_L	844_W	1.579	1.00
909_L	941_Q	1.568	1.00
44_L	153_I	1.567	1.00
987_L	1012_L	1.561	1.00
640_A	667_A	1.560	1.00
788_D	792_H	1.557	1.00
472_P	663_K	1.555	1.00
548_L	553_P	1.555	1.00
305_T	308_E	1.551	1.00
476_D	516_V	1.541	1.00
462_A	490_V	1.538	1.00
830_A	833_E	1.538	1.00
212_P	405_T	1.531	1.00
481_F	516_V	1.522	1.00
419_Q	432_D	1.521	1.00
1027_G	1031_V	1.510	1.00
545_K	549_E	1.507	1.00
691_H	722_S	1.506	1.00
219_S	399_Q	1.502	1.00
456_T	459_A	1.500	1.00
720_F	745_L	1.496	1.00
858_D	955_R	1.490	1.00
979_I	982_A	1.487	1.00
784_L	842_A	1.486	1.00
674_D	677_A	1.485	1.00
261_G	300_I	1.483	1.00
195_A	199_E	1.481	1.00
463_E	467_K	1.480	1.00
295_P	331_I	1.478	1.00
250_D	314_A	1.478	1.00
681_F	685_Y	1.475	1.00
539_Y	646_S	1.474	1.00
623_R	722_S	1.473	1.00
825_I	835_M	1.472	1.00
1005_H	1026_P	1.471	1.00
1005_H	1008_L	1.465	1.00
100_L	123_I	1.464	1.00
895_A	903_R	1.463	1.00
873_D	891_V	1.463	1.00
524_A	528_A	1.459	1.00
519_T	654_F	1.458	1.00
1007_L	1026_P	1.455	1.00
338_A	341_D	1.449	1.00
299_H	304_E	1.443	1.00
978_T	982_A	1.441	1.00
1005_H	1009_A	1.437	1.00
114_G	117_L	1.434	1.00
977_E	995_A	1.432	1.00
39_V	130_W	1.431	1.00
980_I	1035_V	1.426	1.00
691_H	694_P	1.423	1.00
865_Q	933_H	1.422	1.00
50_A	53_A	1.421	1.00
254_A	309_L	1.420	1.00
44_L	132_W	1.419	1.00
623_R	691_H	1.418	1.00
461_V	465_A	1.417	1.00
613_V	810_A	1.416	1.00
12_P	68_E	1.416	1.00
36_T	366_Q	1.416	1.00
460_L	621_V	1.413	1.00
643_T	691_H	1.410	1.00
1005_H	1010_M	1.408	1.00
895_A	898_T	1.405	1.00
208_A	211_S	1.402	1.00
649_V	754_D	1.400	1.00
257_A	271_A	1.394	1.00
97_A	131_Y	1.394	1.00
755_V	804_L	1.390	1.00
248_R	390_L	1.386	1.00
255_L	420_F	1.383	1.00
918_D	921_A	1.382	1.00
472_P	482_S	1.382	1.00
531_A	597_T	1.380	1.00
193_D	325_R	1.379	1.00
196_F	320_M	1.376	1.00
62_F	140_L	1.374	1.00
521_A	525_I	1.371	1.00
55_A	152_Q	1.370	1.00
533_L	551_A	1.369	1.00
301_A	304_E	1.369	1.00
60_M	73_V	1.367	1.00
875_V	929_T	1.364	1.00
1016_L	1022_R	1.361	1.00
559_T	562_Q	1.361	1.00
38_E	128_N	1.360	1.00
973_K	1036_A	1.356	1.00
541_D	545_K	1.355	1.00
472_P	475_A	1.355	1.00
1011_K	1015_Q	1.354	1.00
649_V	722_S	1.349	1.00
791_M	803_Y	1.348	1.00
981_A	995_A	1.347	1.00
263_L	409_H	1.344	1.00
414_K	418_A	1.344	1.00
722_S	754_D	1.340	1.00
88_R	124_Q	1.338	1.00
785_R	829_F	1.336	1.00
560_D	578_N	1.336	1.00
461_V	523_H	1.334	1.00
640_A	682_F	1.331	1.00
980_I	1039_A	1.326	1.00
458_S	617_Q	1.324	1.00
584_Q	588_P	1.322	1.00
110_R	113_S	1.322	1.00
592_S	596_H	1.321	1.00
969_G	994_D	1.320	1.00
407_I	411_E	1.320	1.00
479_Y	489_Q	1.317	1.00
550_D	816_R	1.316	1.00
495_N	584_Q	1.315	1.00
85_I	121_Q	1.313	1.00
877_Q	885_A	1.313	1.00
230_E	418_A	1.312	1.00
623_R	753_V	1.311	1.00
669_P	672_H	1.305	1.00
502_V	508_V	1.305	1.00
228_K	389_D	1.303	1.00
300_I	304_E	1.302	1.00
801_D	837_R	1.300	1.00
416_L	431_V	1.299	1.00
651_V	753_V	1.298	1.00
976_S	979_I	1.291	1.00
41_S	122_L	1.290	1.00
505_G	597_T	1.289	1.00
477_A	668_E	1.289	1.00
502_V	528_A	1.288	1.00
445_L	796_P	1.287	1.00
56_D	173_P	1.286	1.00
637_D	689_T	1.285	1.00
786_I	802_L	1.285	1.00
191_Q	195_A	1.285	1.00
689_T	718_Q	1.278	1.00
883_E	912_Q	1.276	1.00
638_V	665_V	1.275	1.00
1009_A	1013_A	1.274	1.00
420_F	431_V	1.273	1.00
460_L	625_L	1.269	1.00
909_L	922_L	1.269	1.00
973_K	977_E	1.268	1.00
239_L	421_A	1.267	1.00
94_H	98_Q	1.263	1.00
827_D	835_M	1.261	1.00
541_D	565_R	1.260	1.00
628_Q	660_A	1.259	1.00
623_R	653_E	1.258	1.00
649_V	652_W	1.255	1.00
652_W	745_L	1.254	1.00
691_H	696_M	1.253	1.00
455_T	459_A	1.250	1.00
876_M	907_G	1.248	1.00
440_A	444_Q	1.247	1.00
219_S	397_N	1.246	1.00
458_S	592_S	1.246	1.00
440_A	443_A	1.245	1.00
512_L	521_A	1.245	1.00
156_I	168_A	1.243	1.00
298_I	313_L	1.242	1.00
441_Q	444_Q	1.240	1.00
549_E	609_R	1.237	1.00
976_S	1042_I	1.234	1.00
981_A	993_Q	1.225	1.00
623_R	752_A	1.224	1.00
104_D	135_R	1.224	1.00
641_Q	666_M	1.220	1.00
1010_M	1026_P	1.217	1.00
642_K	692_F	1.217	1.00
104_D	107_Q	1.216	1.00
207_P	341_D	1.215	1.00
1013_A	1029_V	1.215	1.00
194_A	198_A	1.215	1.00
99_A	103_A	1.213	1.00
303_Q	429_G	1.212	1.00
558_T	562_Q	1.212	1.00
252_A	351_I	1.210	1.00
702_A	733_E	1.206	1.00
1028_Q	1031_V	1.205	1.00
509_A	548_L	1.203	1.00
726_L	744_N	1.201	1.00
258_L	416_L	1.200	1.00
235_E	418_A	1.199	1.00
1000_F	1030_M	1.199	1.00
61_R	114_G	1.198	1.00
12_P	182_Q	1.195	1.00
657_P	662_A	1.194	1.00
819_L	823_R	1.191	1.00
697_L	721_C	1.190	1.00
315_A	319_K	1.189	1.00
1009_A	1026_P	1.188	1.00
785_R	827_D	1.185	1.00
923_Q	927_R	1.182	1.00
550_D	609_R	1.181	1.00
349_L	413_L	1.181	1.00
258_L	309_L	1.181	1.00
891_V	907_G	1.176	1.00
465_A	487_R	1.175	1.00
476_D	479_Y	1.173	1.00
642_K	754_D	1.172	1.00
551_A	602_F	1.169	1.00
450_V	781_N	1.167	1.00
911_S	941_Q	1.167	1.00
227_L	410_A	1.163	1.00
34_E	366_Q	1.161	1.00
862_I	867_I	1.161	1.00
235_E	422_A	1.159	1.00
475_A	480_L	1.159	1.00
225_L	403_E	1.157	1.00
970_R	1036_A	1.156	1.00
722_S	752_A	1.155	1.00
254_A	313_L	1.155	1.00
1005_H	1016_L	1.151	1.00
40_D	157_Y	1.146	1.00
615_V	810_A	1.146	1.00
841_V	856_S	1.145	1.00
452_I	781_N	1.144	1.00
50_A	156_I	1.144	1.00
426_L	430_D	1.142	1.00
804_L	838_T	1.140	1.00
652_W	722_S	1.140	1.00
751_A	809_L	1.140	1.00
252_A	390_L	1.138	1.00
817_P	821_A	1.138	1.00
111_V	139_L	1.137	1.00
40_D	43_L	1.135	1.00
474_L	516_V	1.132	1.00
259_W	413_L	1.132	1.00
869_L	891_V	1.131	1.00
196_F	319_K	1.129	1.00
539_Y	949_A	1.129	1.00
642_K	696_M	1.128	1.00
620_I	753_V	1.127	1.00
693_V	754_D	1.126	1.00
875_V	878_A	1.126	1.00
53_A	76_A	1.126	1.00
430_D	792_H	1.126	1.00
221_S	399_Q	1.125	1.00
349_L	382_L	1.125	1.00
783_G	833_E	1.125	1.00
45_A	80_E	1.125	1.00
686_G	715_T	1.123	1.00
628_Q	656_W	1.123	1.00
1015_Q	1019_Q	1.121	1.00
36_T	364_Q	1.121	1.00
640_A	681_F	1.117	1.00
458_S	526_V	1.117	1.00
779_V	782_T	1.115	1.00
624_L	659_I	1.113	1.00
474_L	519_T	1.113	1.00
923_Q	939_L	1.111	1.00
517_F	559_T	1.110	1.00
727_P	730_L	1.110	1.00
895_A	900_G	1.109	1.00
4_H	70_W	1.109	1.00
796_P	844_W	1.109	1.00
653_E	745_L	1.108	1.00
614_M	814_L	1.108	1.00
411_E	435_L	1.106	1.00
1016_L	1042_I	1.106	1.00
751_A	804_L	1.104	1.00
441_Q	445_L	1.104	1.00
615_V	752_A	1.101	1.00
623_R	696_M	1.100	1.00
225_L	410_A	1.100	1.00
462_A	491_V	1.097	1.00
652_W	696_M	1.096	1.00
633_L	662_A	1.095	1.00
810_A	824_F	1.093	1.00
925_Q	929_T	1.091	1.00
14_I	289_P	1.091	1.00
244_S	311_T	1.089	1.00
731_C	742_L	1.088	1.00
9_A	181_Y	1.087	1.00
122_L	132_W	1.085	1.00
1032_A	1037_K	1.084	1.00
490_V	524_A	1.083	1.00
643_T	692_F	1.082	1.00
694_P	730_L	1.081	1.00
634_T	637_D	1.080	1.00
200_Q	319_K	1.080	1.00
1009_A	1029_V	1.077	1.00
555_L	573_T	1.077	1.00
984_F	1004_G	1.076	1.00
235_E	421_A	1.073	1.00
641_Q	664_L	1.072	1.00
546_M	550_D	1.071	1.00
62_F	139_L	1.070	1.00
734_W	742_L	1.069	1.00
196_F	200_Q	1.067	1.00
233_D	390_L	1.066	1.00
542_D	546_M	1.065	1.00
505_G	530_A	1.064	1.00
751_A	755_V	1.062	1.00
692_F	697_L	1.059	1.00
402_D	405_T	1.058	1.00
653_E	754_D	1.056	1.00
380_L	392_I	1.056	1.00
627_M	652_W	1.056	1.00
743_H	759_P	1.055	1.00
63_T	72_W	1.052	1.00
690_T	716_L	1.051	1.00
985_S	992_V	1.051	1.00
379_E	395_L	1.050	1.00
32_Y	131_Y	1.050	1.00
224_I	395_L	1.050	1.00
1012_L	1038_L	1.049	1.00
500_R	555_L	1.049	1.00
922_L	939_L	1.048	1.00
401_Y	406_L	1.048	1.00
177_V	180_E	1.048	1.00
512_L	557_I	1.047	1.00
396_A	406_L	1.047	1.00
623_R	755_V	1.046	1.00
207_P	210_L	1.041	1.00
446_N	781_N	1.041	1.00
624_L	656_W	1.038	1.00
718_Q	743_H	1.036	1.00
698_A	727_P	1.036	1.00
1016_L	1024_V	1.034	1.00
199_E	202_R	1.034	1.00
253_L	349_L	1.034	1.00
995_A	1036_A	1.033	1.00
657_P	664_L	1.030	1.00
261_G	264_C	1.029	1.00
1016_L	1020_V	1.027	1.00
522_L	654_F	1.027	1.00
728_A	732_R	1.027	1.00
223_D	396_A	1.025	1.00
893_N	903_R	1.025	1.00
246_V	250_D	1.025	1.00
461_V	487_R	1.025	1.00
1022_R	1042_I	1.024	1.00
879_L	922_L	1.024	1.00
459_A	462_A	1.023	1.00
777_Y	849_A	1.022	1.00
489_Q	492_A	1.021	1.00
1013_A	1017_S	1.021	1.00
539_Y	933_H	1.018	1.00
858_D	873_D	1.016	1.00
785_R	805_T	1.015	1.00
97_A	123_I	1.014	1.00
648_D	748_P	1.012	1.00
526_V	598_A	1.011	1.00
516_V	520_L	1.011	1.00
104_D	121_Q	1.009	1.00
32_Y	133_Y	1.009	1.00
252_A	382_L	1.009	1.00
694_P	754_D	1.007	1.00
531_A	600_I	1.006	1.00
786_I	794_V	1.006	1.00
588_P	592_S	1.005	1.00
513_P	559_T	1.005	1.00
238_Q	243_L	1.005	1.00
756_S	775_I	1.001	1.00
496_L	575_L	0.999	1.00
748_P	754_D	0.999	1.00
408_Q	412_R	0.998	1.00
482_S	485_E	0.998	1.00
468_T	484_R	0.998	1.00
8_V	174_F	0.998	1.00
560_D	576_C	0.996	1.00
919_T	939_L	0.996	1.00
120_H	134_Q	0.994	1.00
980_I	1038_L	0.993	1.00
976_S	1020_V	0.993	1.00
101_M	133_Y	0.992	1.00
49_V	78_T	0.989	1.00
722_S	745_L	0.988	1.00
649_V	748_P	0.987	1.00
894_Q	960_L	0.985	1.00
721_C	726_L	0.983	1.00
203_Q	297_G	0.982	1.00
59_R	73_V	0.979	1.00
532_W	651_V	0.979	1.00
990_C	993_Q	0.978	1.00
698_A	730_L	0.977	1.00
694_P	697_L	0.977	1.00
509_A	535_L	0.976	1.00
34_E	131_Y	0.975	1.00
693_V	745_L	0.973	1.00
945_L	953_L	0.969	1.00
726_L	731_C	0.966	1.00
246_V	310_A	0.966	1.00
662_A	688_T	0.966	1.00
653_E	696_M	0.966	1.00
18_E	23_L	0.965	1.00
803_Y	825_I	0.965	1.00
252_A	349_L	0.965	1.00
642_K	672_H	0.965	1.00
803_Y	837_R	0.964	1.00
65_D	68_E	0.963	1.00
228_K	391_S	0.962	1.00
581_L	584_Q	0.962	1.00
415_M	435_L	0.961	1.00
668_E	677_A	0.959	1.00
697_L	719_V	0.958	1.00
244_S	310_A	0.957	1.00
984_F	1038_L	0.956	1.00
584_Q	587_A	0.955	1.00
560_D	579_A	0.954	1.00
725_A	852_Y	0.953	1.00
698_A	729_D	0.952	1.00
623_R	627_M	0.951	1.00
799_A	856_S	0.951	1.00
226_R	392_I	0.949	1.00
879_L	926_L	0.947	1.00
719_V	734_W	0.945	1.00
43_L	161_L	0.944	1.00
987_L	1008_L	0.943	1.00
120_H	132_W	0.943	1.00
479_Y	516_V	0.943	1.00
61_R	72_W	0.941	1.00
448_T	781_N	0.941	1.00
463_E	466_A	0.941	1.00
267_M	789_A	0.939	1.00
692_F	754_D	0.939	1.00
870_G	873_D	0.938	1.00
432_D	792_H	0.936	1.00
788_D	794_V	0.936	1.00
618_T	807_I	0.936	1.00
696_M	754_D	0.935	1.00
100_L	121_Q	0.934	1.00
585_G	588_P	0.934	1.00
304_E	308_E	0.931	1.00
758_Y	761_F	0.929	1.00
908_Y	958_L	0.929	1.00
779_V	808_Q	0.929	1.00
642_K	734_W	0.927	1.00
697_L	754_D	0.926	1.00
236_F	251_L	0.926	1.00
622_N	807_I	0.926	1.00
495_N	498_R	0.925	1.00
499_E	583_P	0.925	1.00
191_Q	194_A	0.924	1.00
633_L	689_T	0.922	1.00
250_D	318_K	0.921	1.00
330_Q	333_R	0.920	1.00
29_V	141_V	0.920	1.00
498_R	592_S	0.920	1.00
496_L	499_E	0.916	1.00
43_L	157_Y	0.915	1.00
461_V	659_I	0.915	1.00
253_L	271_A	0.915	1.00
13_G	329_E	0.913	1.00
1035_V	1038_L	0.913	1.00
317_L	321_R	0.912	1.00
756_S	850_V	0.908	1.00
462_A	587_A	0.906	1.00
45_A	81_L	0.906	1.00
623_R	642_K	0.905	1.00
677_A	680_Q	0.905	1.00
239_L	244_S	0.904	1.00
643_T	653_E	0.899	1.00
439_Y	442_L	0.897	1.00
253_L	317_L	0.895	1.00
979_I	1020_V	0.895	1.00
626_W	779_V	0.895	1.00
873_D	907_G	0.895	1.00
682_F	715_T	0.892	1.00
787_L	835_M	0.891	1.00
623_R	649_V	0.888	1.00
350_N	379_E	0.888	1.00
650_S	654_F	0.887	1.00
667_A	678_M	0.885	1.00
842_A	852_Y	0.885	1.00
475_A	665_V	0.884	1.00
827_D	830_A	0.883	1.00
682_F	686_G	0.883	1.00
627_M	691_H	0.880	1.00
534_P	749_T	0.876	1.00
643_T	754_D	0.874	1.00
308_E	311_T	0.874	1.00
623_R	745_L	0.874	1.00
701_V	734_W	0.874	1.00
312_R	316_Q	0.873	1.00
542_D	609_R	0.873	1.00
489_Q	520_L	0.870	1.00
124_Q	130_W	0.870	1.00
435_L	438_E	0.867	1.00
233_D	237_R	0.867	1.00
39_V	122_L	0.867	1.00
726_L	742_L	0.864	1.00
1008_L	1011_K	0.863	1.00
174_F	177_V	0.863	1.00
488_E	492_A	0.860	1.00
275_F	321_R	0.860	1.00
879_L	921_A	0.860	1.00
642_K	667_A	0.859	1.00
627_M	745_L	0.858	1.00
693_V	722_S	0.858	1.00
443_A	446_N	0.857	1.00
9_A	182_Q	0.856	1.00
649_V	745_L	0.854	1.00
691_H	753_V	0.854	1.00
599_Y	615_V	0.854	1.00
641_Q	691_H	0.853	1.00
246_V	251_L	0.852	1.00
57_T	62_F	0.851	1.00
626_W	693_V	0.850	1.00
1016_L	1026_P	0.849	1.00
643_T	652_W	0.848	1.00
1005_H	1022_R	0.847	1.00
491_V	587_A	0.847	1.00
891_V	905_L	0.847	1.00
534_P	601_I	0.846	1.00
1010_M	1014_A	0.846	1.00
533_L	553_P	0.845	1.00
691_H	697_L	0.844	1.00
456_T	617_Q	0.843	1.00
415_M	419_Q	0.842	1.00
641_Q	649_V	0.839	1.00
881_D	925_Q	0.839	1.00
39_V	44_L	0.839	1.00
1016_L	1025_T	0.838	1.00
972_P	995_A	0.837	1.00
248_R	351_I	0.836	1.00
731_C	760_A	0.834	1.00
328_A	332_V	0.834	1.00
774_P	849_A	0.833	1.00
430_D	790_M	0.833	1.00
457_L	526_V	0.833	1.00
542_D	545_K	0.832	1.00
189_A	192_R	0.832	1.00
520_L	524_A	0.832	1.00
293_V	348_V	0.831	1.00
507_S	530_A	0.830	1.00
970_R	973_K	0.830	1.00
643_T	745_L	0.830	1.00
13_G	289_P	0.830	1.00
993_Q	1002_L	0.829	1.00
718_Q	741_P	0.828	1.00
697_L	734_W	0.828	1.00
894_Q	898_T	0.827	1.00
539_Y	544_L	0.827	1.00
123_I	133_Y	0.827	1.00
249_T	273_F	0.826	1.00
626_W	630_H	0.826	1.00
969_G	972_P	0.826	1.00
977_E	1039_A	0.826	1.00
755_V	784_L	0.825	1.00
488_E	585_G	0.825	1.00
981_A	985_S	0.824	1.00
235_E	238_Q	0.824	1.00
751_A	754_D	0.823	1.00
641_Q	652_W	0.823	1.00
735_Q	762_G	0.823	1.00
626_W	780_W	0.822	1.00
93_P	96_T	0.821	1.00
7_L	62_F	0.821	1.00
881_D	912_Q	0.819	1.00
601_I	749_T	0.818	1.00
620_I	651_V	0.818	1.00
30_A	135_R	0.817	1.00
225_L	406_L	0.817	1.00
151_R	155_N	0.816	1.00
691_H	755_V	0.815	1.00
1005_H	1020_V	0.814	1.00
259_W	263_L	0.813	1.00
678_M	696_M	0.813	1.00
7_L	139_L	0.813	1.00
250_D	310_A	0.811	1.00
491_V	588_P	0.811	1.00
479_Y	517_F	0.810	1.00
682_F	690_T	0.810	1.00
693_V	696_M	0.810	1.00
641_Q	653_E	0.809	1.00
775_I	852_Y	0.809	1.00
305_T	427_L	0.809	1.00
656_W	754_D	0.808	1.00
862_I	903_R	0.808	1.00
42_P	45_A	0.807	1.00
16_M	20_L	0.807	1.00
745_L	757_W	0.805	1.00
507_S	553_P	0.805	1.00
156_I	166_T	0.804	1.00
925_Q	928_E	0.803	1.00
641_Q	754_D	0.803	1.00
236_F	421_A	0.802	1.00
171_F	286_A	0.801	1.00
795_P	798_V	0.801	1.00
491_V	498_R	0.800	1.00
10_A	289_P	0.800	1.00
640_A	687_V	0.800	1.00
652_W	755_V	0.799	1.00
619_A	622_N	0.799	1.00
547_M	646_S	0.799	1.00
691_H	721_C	0.798	1.00
619_A	810_A	0.797	1.00
921_A	924_A	0.797	1.00
631_Y	652_W	0.796	1.00
626_W	745_L	0.795	1.00
924_A	928_E	0.794	1.00
982_A	986_S	0.791	1.00
624_L	655_F	0.791	1.00
650_S	691_H	0.791	1.00
627_M	722_S	0.791	1.00
633_L	637_D	0.791	1.00
844_W	850_V	0.790	1.00
155_N	164_E	0.789	1.00
108_D	119_F	0.789	1.00
97_A	101_M	0.789	1.00
258_L	428_C	0.788	1.00
253_L	257_A	0.787	1.00
458_S	462_A	0.787	1.00
554_S	573_T	0.787	1.00
649_V	692_F	0.786	1.00
512_L	559_T	0.785	1.00
458_S	465_A	0.785	1.00
649_V	653_E	0.784	1.00
446_N	844_W	0.784	1.00
649_V	753_V	0.783	1.00
227_L	414_K	0.782	1.00
511_A	544_L	0.782	1.00
785_R	835_M	0.782	1.00
173_P	176_D	0.781	1.00
627_M	754_D	0.780	1.00
583_P	588_P	0.780	1.00
692_F	696_M	0.780	1.00
691_H	751_A	0.780	1.00
413_L	417_I	0.779	1.00
498_R	591_L	0.779	1.00
755_V	808_Q	0.779	1.00
650_S	653_E	0.777	1.00
61_R	116_P	0.776	1.00
642_K	652_W	0.776	1.00
842_A	853_L	0.775	1.00
51_G	149_I	0.775	1.00
896_A	904_Q	0.774	1.00
1029_V	1038_L	0.774	1.00
92_D	95_G	0.773	1.00
240_A	246_V	0.773	1.00
1010_M	1027_G	0.772	1.00
652_W	693_V	0.772	1.00
519_T	658_F	0.772	1.00
486_M	520_L	0.770	1.00
615_V	619_A	0.769	1.00
56_D	59_R	0.769	1.00
980_I	1012_L	0.769	1.00
722_S	748_P	0.769	1.00
454_E	618_T	0.768	1.00
576_C	579_A	0.768	1.00
250_D	321_R	0.767	1.00
638_V	686_G	0.766	1.00
84_I	124_Q	0.765	1.00
5_L	73_V	0.765	1.00
652_W	697_L	0.765	1.00
639_V	657_P	0.764	1.00
464_Q	469_P	0.763	1.00
136_Y	140_L	0.763	1.00
259_W	409_H	0.763	1.00
752_A	755_V	0.763	1.00
516_V	666_M	0.762	1.00
842_A	850_V	0.762	1.00
904_Q	938_V	0.762	1.00
652_W	753_V	0.762	1.00
215_L	400_R	0.761	1.00
195_A	198_A	0.761	1.00
374_P	395_L	0.761	1.00
248_R	421_A	0.761	1.00
649_V	696_M	0.761	1.00
876_M	885_A	0.760	1.00
745_L	753_V	0.759	1.00
226_R	391_S	0.758	1.00
492_A	496_L	0.757	1.00
803_Y	835_M	0.757	1.00
533_L	547_M	0.756	1.00
348_V	379_E	0.755	1.00
555_L	575_L	0.755	1.00
787_L	793_P	0.755	1.00
873_D	955_R	0.755	1.00
626_W	754_D	0.754	1.00
450_V	629_N	0.753	1.00
415_M	418_A	0.753	1.00
193_D	326_Y	0.753	1.00
299_H	312_R	0.752	1.00
226_R	393_E	0.752	1.00
1014_A	1017_S	0.752	1.00
995_A	1039_A	0.750	1.00
512_L	558_T	0.749	1.00
546_M	816_R	0.749	1.00
1028_Q	1032_A	0.749	1.00
784_L	850_V	0.748	1.00
639_V	692_F	0.748	1.00
511_A	535_L	0.748	1.00
563_L	576_C	0.747	1.00
805_T	833_E	0.747	1.00
300_I	428_C	0.746	1.00
28_S	135_R	0.746	1.00
498_R	588_P	0.744	1.00
631_Y	745_L	0.740	1.00
44_L	157_Y	0.740	1.00
233_D	248_R	0.739	1.00
256_A	413_L	0.739	1.00
627_M	656_W	0.739	1.00
392_I	410_A	0.738	1.00
495_N	587_A	0.738	1.00
623_R	693_V	0.737	1.00
643_T	696_M	0.737	1.00
828_P	835_M	0.736	1.00
692_F	700_F	0.736	1.00
755_V	782_T	0.735	1.00
843_R	853_L	0.735	1.00
35_L	365_A	0.734	1.00
252_A	413_L	0.734	1.00
259_W	412_R	0.733	1.00
1033_S	1038_L	0.733	1.00
803_Y	823_R	0.732	1.00
492_A	495_N	0.731	1.00
119_F	135_R	0.730	1.00
583_P	587_A	0.729	1.00
1033_S	1037_K	0.727	1.00
234_G	238_Q	0.727	1.00
174_F	290_V	0.727	1.00
1007_L	1016_L	0.726	1.00
237_R	241_T	0.725	1.00
194_A	330_Q	0.724	1.00
126_A	129_R	0.724	1.00
878_A	925_Q	0.724	1.00
37_G	130_W	0.724	1.00
581_L	585_G	0.724	1.00
255_L	413_L	0.724	1.00
54_Q	168_A	0.724	1.00
152_Q	287_T	0.723	1.00
4_H	65_D	0.723	1.00
104_D	119_F	0.722	1.00
885_A	926_L	0.722	1.00
41_S	84_I	0.720	1.00
649_V	693_V	0.719	1.00
176_D	180_E	0.718	1.00
509_A	551_A	0.718	1.00
927_R	932_P	0.718	1.00
641_Q	734_W	0.718	1.00
778_P	784_L	0.718	1.00
984_F	1012_L	0.717	1.00
486_M	523_H	0.717	1.00
974_A	977_E	0.716	1.00
267_M	299_H	0.716	1.00
639_V	754_D	0.715	1.00
652_W	656_W	0.715	1.00
143_G	352_K	0.715	1.00
782_T	808_Q	0.714	1.00
758_Y	773_V	0.713	1.00
722_S	755_V	0.713	1.00
667_A	671_A	0.713	1.00
694_P	698_A	0.712	1.00
972_P	981_A	0.712	1.00
493_L	496_L	0.712	1.00
1015_Q	1018_R	0.711	1.00
986_S	1019_Q	0.711	1.00
743_H	757_W	0.711	1.00
255_L	416_L	0.710	1.00
656_W	691_H	0.710	1.00
333_R	1005_H	0.709	1.00
633_L	656_W	0.708	1.00
639_V	689_T	0.707	1.00
238_Q	241_T	0.706	1.00
256_A	382_L	0.706	1.00
321_R	324_Q	0.706	1.00
134_Q	149_I	0.706	1.00
885_A	907_G	0.706	1.00
691_H	726_L	0.706	1.00
283_A	286_A	0.706	1.00
522_L	645_C	0.705	1.00
327_D	330_Q	0.705	1.00
969_G	997_A	0.705	1.00
10_A	13_G	0.704	1.00
643_T	748_P	0.704	1.00
460_L	659_I	0.702	1.00
102_Q	106_Q	0.702	1.00
239_L	251_L	0.701	1.00
82_P	85_I	0.700	1.00
492_A	585_G	0.700	1.00
204_L	208_A	0.700	1.00
229_L	414_K	0.699	1.00
980_I	983_A	0.699	1.00
1007_L	1033_S	0.698	1.00
144_F	276_M	0.698	1.00
478_R	684_E	0.697	1.00
695_S	947_L	0.696	1.00
495_N	589_L	0.695	1.00
187_S	190_W	0.694	1.00
676_L	703_S	0.694	1.00
412_R	435_L	0.692	1.00
627_M	779_V	0.692	1.00
118_V	134_Q	0.692	1.00
623_R	650_S	0.691	1.00
39_V	363_V	0.691	1.00
550_D	815_G	0.691	1.00
513_P	669_P	0.690	1.00
57_T	60_M	0.688	1.00
478_R	685_Y	0.688	1.00
230_E	414_K	0.688	1.00
227_L	411_E	0.687	1.00
642_K	691_H	0.687	1.00
975_G	979_I	0.687	1.00
172_T	176_D	0.686	1.00
224_I	393_E	0.686	1.00
472_P	476_D	0.685	1.00
233_D	389_D	0.685	1.00
690_T	719_V	0.685	1.00
1017_S	1022_R	0.684	1.00
967_A	1001_A	0.683	1.00
626_W	642_K	0.683	1.00
597_T	616_G	0.682	1.00
493_L	557_I	0.682	1.00
693_V	701_V	0.681	1.00
652_W	694_P	0.681	1.00
691_H	720_F	0.681	1.00
892_I	908_Y	0.681	1.00
791_M	828_P	0.681	1.00
872_I	905_L	0.681	1.00
692_F	734_W	0.680	1.00
649_V	721_C	0.680	1.00
901_D	904_Q	0.680	1.00
651_V	655_F	0.679	1.00
205_P	270_A	0.678	1.00
732_R	736_Q	0.678	1.00
152_Q	156_I	0.678	1.00
50_A	166_T	0.678	1.00
47_A	156_I	0.678	1.00
639_V	691_H	0.678	1.00
642_K	701_V	0.678	1.00
141_V	146_F	0.677	1.00
657_P	660_A	0.677	1.00
805_T	809_L	0.676	1.00
92_D	96_T	0.676	1.00
1013_A	1026_P	0.676	1.00
1013_A	1027_G	0.675	1.00
805_T	827_D	0.675	1.00
511_A	537_T	0.674	1.00
36_T	128_N	0.672	1.00
507_S	597_T	0.671	1.00
350_N	353_V	0.671	1.00
644_P	691_H	0.671	1.00
997_A	1002_L	0.671	1.00
98_Q	102_Q	0.670	1.00
639_V	745_L	0.670	1.00
816_R	822_S	0.670	1.00
386_V	389_D	0.669	1.00
985_S	991_D	0.669	1.00
935_V	939_L	0.669	1.00
471_A	636_E	0.669	1.00
744_N	775_I	0.668	1.00
508_V	530_A	0.668	1.00
640_A	678_M	0.667	1.00
791_M	835_M	0.667	1.00
721_C	745_L	0.666	1.00
256_A	271_A	0.665	1.00
940_L	961_P	0.665	1.00
231_F	234_G	0.664	1.00
54_Q	171_F	0.664	1.00
923_Q	1001_A	0.664	1.00
512_L	518_L	0.663	1.00
474_L	481_F	0.663	1.00
646_S	950_N	0.663	1.00
230_E	233_D	0.662	1.00
172_T	286_A	0.662	1.00
502_V	555_L	0.662	1.00
456_T	592_S	0.662	1.00
859_Q	868_E	0.660	1.00
274_I	350_N	0.659	1.00
501_G	530_A	0.659	1.00
87_L	93_P	0.658	1.00
32_Y	101_M	0.658	1.00
639_V	649_V	0.657	1.00
382_L	390_L	0.657	1.00
267_M	301_A	0.657	1.00
460_L	464_Q	0.656	1.00
43_L	47_A	0.656	1.00
411_E	414_K	0.656	1.00
623_R	626_W	0.656	1.00
1007_L	1011_K	0.655	1.00
54_Q	156_I	0.655	1.00
455_T	460_L	0.654	1.00
326_Y	331_I	0.654	1.00
559_T	578_N	0.653	0.99
513_P	561_D	0.652	0.99
125_V	131_Y	0.652	0.99
639_V	748_P	0.650	0.99
980_I	1042_I	0.650	0.99
665_V	685_Y	0.650	0.99
300_I	309_L	0.650	0.99
719_V	740_A	0.650	0.99
588_P	591_L	0.650	0.99
672_H	693_V	0.650	0.99
450_V	780_W	0.649	0.99
552_R	815_G	0.649	0.99
692_F	721_C	0.649	0.99
346_G	377_D	0.647	0.99
791_M	825_I	0.647	0.99
651_V	754_D	0.646	0.99
64_E	67_G	0.645	0.99
116_P	140_L	0.644	0.99
199_E	319_K	0.644	0.99
1004_G	1009_A	0.643	0.99
52_L	79_F	0.643	0.99
640_A	652_W	0.643	0.99
1026_P	1033_S	0.643	0.99
722_S	751_A	0.643	0.99
543_R	871_E	0.642	0.99
869_L	905_L	0.642	0.99
883_E	910_V	0.641	0.99
692_F	748_P	0.641	0.99
694_P	721_C	0.640	0.99
452_I	807_I	0.640	0.99
434_M	438_E	0.639	0.99
626_W	652_W	0.639	0.99
954_D	957_A	0.639	0.99
592_S	617_Q	0.638	0.99
721_C	754_D	0.638	0.99
353_V	384_P	0.638	0.99
434_M	439_Y	0.638	0.99
600_I	614_M	0.637	0.99
653_E	721_C	0.637	0.99
521_A	524_A	0.636	0.99
622_N	754_D	0.636	0.99
731_C	734_W	0.636	0.99
745_L	748_P	0.636	0.99
295_P	298_I	0.636	0.99
1012_L	1016_L	0.635	0.99
886_V	892_I	0.635	0.99
748_P	755_V	0.635	0.99
746_Y	775_I	0.635	0.99
510_V	525_I	0.635	0.99
694_P	745_L	0.634	0.99
594_P	618_T	0.634	0.99
495_N	585_G	0.634	0.99
1031_V	1041_I	0.634	0.99
200_Q	320_M	0.633	0.99
168_A	171_F	0.633	0.99
639_V	652_W	0.633	0.99
204_L	295_P	0.631	0.99
547_M	612_G	0.631	0.99
406_L	410_A	0.631	0.99
829_F	835_M	0.631	0.99
667_A	672_H	0.631	0.99
49_V	79_F	0.630	0.99
652_W	692_F	0.630	0.99
969_G	981_A	0.630	0.99
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748_P	752_A	0.630	0.99
145_S	287_T	0.629	0.99
497_L	501_G	0.628	0.99
631_Y	720_F	0.628	0.99
880_P	925_Q	0.628	0.99
295_P	344_L	0.627	0.99
614_M	811_Q	0.627	0.99
908_Y	942_L	0.626	0.99
639_V	653_E	0.626	0.99
642_K	649_V	0.626	0.99
682_F	687_V	0.625	0.99
258_L	306_L	0.625	0.99
558_T	576_C	0.625	0.99
627_M	649_V	0.624	0.99
869_L	934_M	0.624	0.99
642_K	720_F	0.624	0.99
620_I	752_A	0.624	0.99
45_A	84_I	0.623	0.99
77_L	114_G	0.623	0.99
275_F	294_L	0.623	0.99
651_V	734_W	0.623	0.99
983_A	987_L	0.622	0.99
256_A	394_I	0.622	0.99
639_V	662_A	0.621	0.99
641_Q	650_S	0.621	0.99
884_Q	945_L	0.621	0.99
512_L	577_Y	0.621	0.99
642_K	722_S	0.620	0.99
985_S	990_C	0.620	0.99
1005_H	1033_S	0.620	0.99
1028_Q	1045_E	0.619	0.99
158_C	361_P	0.618	0.99
730_L	733_E	0.618	0.99
1013_A	1024_V	0.618	0.99
418_A	422_A	0.618	0.99
908_Y	962_E	0.617	0.99
911_S	914_G	0.617	0.99
314_A	318_K	0.617	0.99
62_F	117_L	0.617	0.99
638_V	688_T	0.616	0.99
823_R	856_S	0.616	0.99
544_L	548_L	0.616	0.99
596_H	811_Q	0.615	0.99
653_E	753_V	0.615	0.99
786_I	844_W	0.615	0.99
695_S	725_A	0.613	0.99
81_L	120_H	0.613	0.99
654_F	658_F	0.613	0.99
724_E	852_Y	0.613	0.99
647_F	650_S	0.612	0.99
509_A	556_L	0.612	0.99
532_W	650_S	0.612	0.99
692_F	745_L	0.612	0.99
642_K	653_E	0.612	0.99
546_M	549_E	0.611	0.99
192_R	195_A	0.610	0.99
6_P	179_E	0.610	0.99
867_I	934_M	0.609	0.99
985_S	993_Q	0.609	0.99
656_W	692_F	0.608	0.99
408_Q	438_E	0.608	0.99
619_A	807_I	0.608	0.99
636_E	688_T	0.608	0.99
650_S	745_L	0.607	0.99
623_R	751_A	0.607	0.99
691_H	695_S	0.606	0.99
649_V	697_L	0.605	0.99
731_C	735_Q	0.605	0.99
656_W	745_L	0.605	0.99
734_W	740_A	0.605	0.99
1016_L	1028_Q	0.604	0.99
85_I	123_I	0.604	0.99
894_Q	961_P	0.604	0.99
130_W	363_V	0.603	0.99
642_K	753_V	0.603	0.99
710_R	713_C	0.603	0.99
1022_R	1025_T	0.603	0.99
95_G	99_A	0.603	0.99
436_P	440_A	0.603	0.99
631_Y	691_H	0.602	0.99
720_F	754_D	0.601	0.99
581_L	587_A	0.600	0.99
906_V	938_V	0.600	0.99
649_V	755_V	0.600	0.99
286_A	290_V	0.600	0.99
548_L	556_L	0.600	0.99
693_V	699_A	0.600	0.99
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641_Q	692_F	0.599	0.99
18_E	24_P	0.598	0.99
500_R	575_L	0.598	0.99
345_F	376_N	0.598	0.99
52_L	118_V	0.597	0.99
538_G	669_P	0.597	0.99
326_Y	334_D	0.596	0.99
556_L	572_L	0.595	0.99
1020_V	1023_Q	0.594	0.99
185_R	190_W	0.594	0.99
47_A	153_I	0.593	0.99
511_A	566_F	0.593	0.99
539_Y	644_P	0.593	0.99
772_S	851_E	0.592	0.99
18_E	22_E	0.592	0.99
136_Y	149_I	0.592	0.99
627_M	643_T	0.592	0.99
56_D	73_V	0.591	0.99
735_Q	761_F	0.590	0.99
639_V	656_W	0.590	0.99
642_K	678_M	0.590	0.99
657_P	691_H	0.589	0.99
33_V	365_A	0.589	0.99
81_L	122_L	0.589	0.99
698_A	733_E	0.589	0.99
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794_V	798_V	0.589	0.99
884_Q	944_Q	0.588	0.99
803_Y	856_S	0.588	0.99
643_T	734_W	0.587	0.99
507_S	814_L	0.586	0.99
65_D	70_W	0.586	0.99
141_V	149_I	0.584	0.99
148_A	287_T	0.584	0.99
109_L	119_F	0.584	0.99
626_W	631_Y	0.584	0.99
1009_A	1027_G	0.584	0.99
28_S	109_L	0.584	0.99
692_F	719_V	0.583	0.99
606_S	870_G	0.583	0.99
672_H	696_M	0.583	0.99
513_P	562_Q	0.582	0.99
1038_L	1041_I	0.581	0.99
695_S	953_L	0.581	0.99
662_A	691_H	0.581	0.99
927_R	935_V	0.580	0.99
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826_A	832_G	0.580	0.99
694_P	725_A	0.580	0.99
959_P	962_E	0.579	0.99
453_P	625_L	0.578	0.99
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1022_R	1045_E	0.577	0.99
626_W	639_V	0.577	0.99
652_W	689_T	0.576	0.99
983_A	1019_Q	0.576	0.99
619_A	808_Q	0.576	0.99
641_Q	745_L	0.575	0.99
691_H	731_C	0.574	0.99
639_V	696_M	0.574	0.99
1024_V	1038_L	0.574	0.99
521_A	577_Y	0.574	0.99
745_L	751_A	0.574	0.99
640_A	671_A	0.573	0.99
246_V	254_A	0.573	0.99
471_A	663_K	0.573	0.99
465_A	484_R	0.573	0.99
721_C	742_L	0.572	0.99
1026_P	1029_V	0.571	0.99
897_A	901_D	0.571	0.99
305_T	425_A	0.571	0.99
701_V	733_E	0.570	0.99
218_R	397_N	0.570	0.99
484_R	487_R	0.570	0.99
18_E	21_S	0.570	0.99
267_M	302_A	0.570	0.99
751_A	782_T	0.570	0.99
498_R	528_A	0.569	0.99
502_V	554_S	0.569	0.99
152_Q	155_N	0.569	0.99
495_N	583_P	0.569	0.99
675_P	696_M	0.568	0.99
556_L	574_S	0.568	0.99
654_F	664_L	0.567	0.99
984_F	999_F	0.566	0.99
748_P	751_A	0.566	0.99
396_A	401_Y	0.565	0.99
639_V	643_T	0.565	0.99
641_Q	657_P	0.565	0.99
306_L	424_P	0.565	0.99
630_H	777_Y	0.565	0.99
1007_L	1022_R	0.565	0.99
456_T	621_V	0.564	0.99
655_F	693_V	0.564	0.99
375_V	395_L	0.563	0.99
495_N	586_S	0.563	0.99
801_D	841_V	0.563	0.99
88_R	130_W	0.563	0.99
691_H	719_V	0.563	0.99
818_D	822_S	0.562	0.99
299_H	302_A	0.562	0.99
34_E	368_H	0.561	0.98
261_G	269_Y	0.561	0.98
649_V	720_F	0.560	0.98
974_A	981_A	0.560	0.98
921_A	925_Q	0.560	0.98
656_W	694_P	0.560	0.98
641_Q	654_F	0.558	0.98
57_T	287_T	0.558	0.98
1013_A	1016_L	0.558	0.98
144_F	353_V	0.558	0.98
491_V	590_Q	0.558	0.98
650_S	754_D	0.558	0.98
141_V	287_T	0.557	0.98
627_M	720_F	0.557	0.98
926_L	935_V	0.557	0.98
515_S	666_M	0.557	0.98
122_L	130_W	0.557	0.98
643_T	721_C	0.556	0.98
485_E	489_Q	0.556	0.98
756_S	804_L	0.556	0.98
894_Q	906_V	0.555	0.98
631_Y	743_H	0.555	0.98
250_D	317_L	0.555	0.98
1017_S	1024_V	0.555	0.98
475_A	638_V	0.555	0.98
819_L	822_S	0.555	0.98
158_C	164_E	0.555	0.98
726_L	760_A	0.554	0.98
273_F	296_L	0.554	0.98
669_P	673_R	0.554	0.98
744_N	852_Y	0.553	0.98
404_P	407_I	0.552	0.98
536_D	539_Y	0.552	0.98
972_P	977_E	0.551	0.98
630_H	759_P	0.551	0.98
679_Q	713_C	0.551	0.98
249_T	253_L	0.551	0.98
641_Q	693_V	0.551	0.98
73_V	175_A	0.550	0.98
306_L	416_L	0.550	0.98
394_I	413_L	0.550	0.98
533_L	602_F	0.550	0.98
39_V	157_Y	0.550	0.98
719_V	742_L	0.550	0.98
693_V	697_L	0.549	0.98
459_A	463_E	0.549	0.98
445_L	448_T	0.549	0.98
485_E	488_E	0.549	0.98
911_S	917_L	0.549	0.98
498_R	589_L	0.549	0.98
1011_K	1014_A	0.548	0.98
1005_H	1025_T	0.548	0.98
190_W	330_Q	0.547	0.98
971_A	995_A	0.547	0.98
690_T	693_V	0.546	0.98
246_V	314_A	0.545	0.98
279_L	324_Q	0.545	0.98
1009_A	1016_L	0.545	0.98
411_E	415_M	0.544	0.98
883_E	911_S	0.544	0.98
319_K	322_R	0.544	0.98
221_S	398_K	0.544	0.98
144_F	355_D	0.542	0.98
1010_M	1025_T	0.542	0.98
412_R	433_I	0.542	0.98
938_V	941_Q	0.541	0.98
306_L	310_A	0.541	0.98
63_T	70_W	0.541	0.98
231_F	388_G	0.541	0.98
525_I	557_I	0.541	0.98
519_T	666_M	0.540	0.98
544_L	565_R	0.540	0.98
3_Q	175_A	0.540	0.98
15_W	69_V	0.539	0.98
619_A	623_R	0.539	0.98
254_A	310_A	0.539	0.98
631_Y	754_D	0.538	0.98
881_D	921_A	0.538	0.98
623_R	656_W	0.537	0.98
269_Y	298_I	0.537	0.98
642_K	745_L	0.536	0.98
734_W	754_D	0.536	0.98
882_V	885_A	0.536	0.98
436_P	439_Y	0.536	0.98
990_C	1002_L	0.535	0.98
688_T	717_K	0.535	0.98
546_M	551_A	0.535	0.98
558_T	578_N	0.535	0.98
1007_L	1023_Q	0.535	0.98
258_L	262_R	0.535	0.98
987_L	1015_Q	0.535	0.98
872_I	875_V	0.535	0.98
584_Q	589_L	0.534	0.98
972_P	994_D	0.534	0.98
154_A	360_I	0.533	0.98
304_E	309_L	0.533	0.98
85_I	100_L	0.533	0.98
41_S	130_W	0.533	0.98
598_A	620_I	0.532	0.98
260_L	347_P	0.531	0.98
13_G	17_A	0.531	0.98
999_F	1012_L	0.531	0.98
372_T	395_L	0.531	0.98
465_A	469_P	0.530	0.98
682_F	700_F	0.530	0.98
233_D	387_H	0.530	0.98
875_V	925_Q	0.530	0.98
697_L	730_L	0.530	0.98
904_Q	937_V	0.530	0.98
696_M	734_W	0.530	0.98
253_L	296_L	0.530	0.98
152_Q	285_T	0.529	0.98
41_S	124_Q	0.529	0.98
853_L	856_S	0.529	0.98
251_L	310_A	0.528	0.98
881_D	911_S	0.528	0.98
652_W	720_F	0.528	0.98
462_A	465_A	0.528	0.98
498_R	583_P	0.528	0.98
777_Y	844_W	0.527	0.98
862_I	865_Q	0.527	0.98
655_F	697_L	0.527	0.98
717_K	741_P	0.526	0.98
898_T	901_D	0.526	0.98
539_Y	546_M	0.526	0.98
624_L	628_Q	0.525	0.98
858_D	869_L	0.525	0.98
748_P	775_I	0.524	0.98
104_D	133_Y	0.524	0.98
716_L	740_A	0.524	0.98
519_T	664_L	0.523	0.98
203_Q	268_D	0.522	0.98
359_D	364_Q	0.521	0.98
360_I	365_A	0.521	0.98
444_Q	447_A	0.521	0.98
858_D	956_K	0.521	0.98
688_T	716_L	0.521	0.98
690_T	754_D	0.520	0.98
651_V	745_L	0.520	0.98
237_R	248_R	0.520	0.98
1010_M	1016_L	0.520	0.98
82_P	104_D	0.520	0.98
439_Y	792_H	0.519	0.98
622_N	697_L	0.519	0.98
96_T	100_L	0.519	0.98
731_C	773_V	0.519	0.98
418_A	421_A	0.519	0.98
32_Y	368_H	0.519	0.98
910_V	942_L	0.518	0.97
623_R	643_T	0.518	0.97
998_D	1034_T	0.518	0.97
982_A	985_S	0.517	0.97
691_H	748_P	0.516	0.97
188_E	191_Q	0.516	0.97
656_W	659_I	0.515	0.97
624_L	691_H	0.514	0.97
562_Q	565_R	0.514	0.97
872_I	934_M	0.514	0.97
653_E	755_V	0.513	0.97
910_V	941_Q	0.513	0.97
627_M	697_L	0.513	0.97
419_Q	426_L	0.513	0.97
751_A	810_A	0.512	0.97
892_I	959_P	0.512	0.97
989_G	1011_K	0.511	0.97
652_W	657_P	0.511	0.97
909_L	919_T	0.511	0.97
138_H	143_G	0.511	0.97
459_A	591_L	0.510	0.97
628_Q	633_L	0.510	0.97
653_E	692_F	0.510	0.97
462_A	466_A	0.510	0.97
754_D	757_W	0.509	0.97
486_M	490_V	0.509	0.97
48_V	81_L	0.509	0.97
731_C	774_P	0.509	0.97
628_Q	652_W	0.508	0.97
627_M	696_M	0.507	0.97
46_R	49_V	0.507	0.97
749_T	753_V	0.507	0.97
382_L	413_L	0.507	0.97
446_N	449_Q	0.507	0.97
481_F	489_Q	0.506	0.97
476_D	668_E	0.506	0.97
622_N	782_T	0.506	0.97
656_W	753_V	0.505	0.97
377_D	397_N	0.505	0.97
696_M	699_A	0.505	0.97
384_P	387_H	0.504	0.97
623_R	655_F	0.504	0.97
258_L	300_I	0.503	0.97
258_L	420_F	0.503	0.97
449_Q	781_N	0.503	0.97
408_Q	846_D	0.502	0.97
999_F	1008_L	0.502	0.97
627_M	657_P	0.502	0.97
971_A	978_T	0.502	0.97
405_T	408_Q	0.502	0.97
655_F	691_H	0.502	0.97
258_L	261_G	0.502	0.97
231_F	389_D	0.501	0.97
143_G	354_F	0.501	0.97
969_G	993_Q	0.500	0.97
689_T	720_F	0.500	0.97

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4dg8A	1	0.3805	100	0.57	Contact Map
4iz6A	2	0.4563	100	0.592	Contact Map
4r0mB	1	0.4532	100	0.605	Contact Map
1amuA	1	0.3906	100	0.632	Contact Map
4d4iA	1	0.3666	100	0.639	Contact Map
3tsyA	2	0.5205	100	0.655	Contact Map
3g7sA	2	0.3627	100	0.66	Contact Map
4gr5A	1	0.3542	100	0.664	Contact Map
3wvnA	1	0.2931	100	0.667	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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