GREMLIN Database
YIBD - Uncharacterized glycosyltransferase YibD
UniProt: P11290 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11266
Length: 344 (285)
Sequences: 10510 (9612)
Seq/√Len: 569.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
173_R177_V3.8191.00
17_A94_A3.5851.00
18_G48_N3.0411.00
14_L49_S2.9961.00
23_T216_Y2.9461.00
105_T210_Q2.7551.00
79_R83_V2.7291.00
193_V197_E2.6651.00
32_T104_E2.5011.00
42_N67_H2.4121.00
82_E182_K2.3781.00
71_A75_V2.3471.00
115_L206_R2.2861.00
48_N51_E2.2671.00
22_R26_E2.2511.00
99_Y214_K2.2391.00
9_S86_G2.2261.00
90_A103_Y2.1471.00
16_N46_T2.1011.00
8_L107_M2.0951.00
50_V54_K2.0871.00
40_I53_A2.0721.00
22_R55_Y2.0711.00
75_V185_A2.0411.00
66_L83_V2.0391.00
37_E64_R2.0191.00
123_D214_K1.9821.00
23_T97_E1.9781.00
109_M206_R1.9361.00
98_V102_M1.9071.00
66_L79_R1.9001.00
11_I80_G1.8891.00
50_V65_L1.8621.00
26_E56_Y1.8581.00
12_I38_I1.8131.00
68_Q71_A1.8051.00
116_D172_R1.7991.00
12_I24_C1.7971.00
88_Y110_A1.7941.00
8_L103_Y1.7891.00
41_I80_G1.7761.00
14_L40_I1.7621.00
109_M208_T1.7521.00
90_A170_V1.7181.00
9_S37_E1.6881.00
77_R93_D1.6781.00
90_A102_M1.6601.00
92_V98_V1.6511.00
33_W107_M1.6511.00
7_K87_K1.6391.00
106_L120_C1.6361.00
97_E214_K1.6221.00
106_L170_V1.6081.00
73_A222_V1.6051.00
84_A173_R1.6011.00
37_E86_G1.5941.00
54_K67_H1.5821.00
12_I28_L1.5551.00
68_Q79_R1.5481.00
50_V67_H1.5221.00
22_R56_Y1.5211.00
68_Q75_V1.5201.00
102_M106_L1.5111.00
15_Y70_N1.5091.00
73_A190_Q1.5011.00
79_R82_E1.4941.00
8_L170_V1.4901.00
104_E108_T1.4771.00
101_T105_T1.4761.00
174_D178_K1.4651.00
53_A65_L1.4611.00
42_N50_V1.4441.00
116_D203_L1.4351.00
25_M56_Y1.4291.00
7_K35_A1.4291.00
88_Y170_V1.4241.00
42_N45_S1.4211.00
44_G68_Q1.4011.00
36_L103_Y1.3931.00
97_E216_Y1.3931.00
107_M111_L1.3921.00
38_I63_V1.3921.00
184_I193_V1.3841.00
28_L92_V1.3811.00
18_G52_I1.3621.00
24_C92_V1.3541.00
175_V198_F1.3531.00
64_R83_V1.3501.00
120_C212_L1.3451.00
125_C214_K1.3431.00
26_E30_T1.3321.00
123_D211_S1.3241.00
54_K57_A1.3081.00
41_I76_A1.3041.00
14_L17_A1.3031.00
179_N182_K1.3021.00
110_A118_A1.2921.00
102_M120_C1.2711.00
89_V173_R1.2671.00
110_A170_V1.2621.00
122_A167_W1.2541.00
33_W36_L1.2511.00
77_R91_F1.2491.00
55_Y59_N1.2481.00
90_A98_V1.2341.00
109_M113_D1.2311.00
81_I89_V1.2301.00
57_A65_L1.2281.00
101_T104_E1.2191.00
17_A20_D1.2181.00
16_N45_S1.2171.00
176_I194_W1.2091.00
30_T100_P1.2041.00
106_L118_A1.2031.00
22_R52_I1.2011.00
97_E125_C1.2001.00
37_E85_T1.1921.00
81_I91_F1.1791.00
175_V203_L1.1721.00
87_K172_R1.1691.00
25_M40_I1.1681.00
64_R85_T1.1551.00
218_H221_S1.1541.00
74_S190_Q1.1501.00
14_L53_A1.1421.00
73_A77_R1.1391.00
169_G195_T1.1371.00
117_V205_A1.1291.00
221_S224_R1.1281.00
29_I63_V1.1201.00
126_F130_G1.1191.00
105_T108_T1.1151.00
25_M38_I1.1141.00
25_M29_I1.1081.00
9_S39_I1.1071.00
73_A166_V1.1031.00
43_D70_N1.0991.00
108_T112_E1.0961.00
75_V79_R1.0951.00
51_E54_K1.0921.00
43_D72_G1.0911.00
54_K65_L1.0861.00
81_I84_A1.0741.00
8_L90_A1.0691.00
67_H79_R1.0661.00
43_D76_A1.0651.00
77_R190_Q1.0651.00
102_M212_L1.0631.00
117_V198_F1.0631.00
74_S78_N1.0571.00
109_M112_E1.0561.00
171_Y195_T1.0451.00
71_A76_A1.0421.00
105_T212_L1.0361.00
178_K201_N1.0351.00
29_I60_Y1.0251.00
82_E180_N1.0181.00
121_N207_Y1.0151.00
113_D206_R1.0121.00
114_D204_R1.0111.00
174_D177_V1.0081.00
13_P76_A1.0031.00
92_V213_Y1.0021.00
116_D204_R0.9961.00
14_L21_F0.9871.00
7_K85_T0.9821.00
13_P94_A0.9821.00
14_L94_A0.9811.00
166_V183_F0.9761.00
10_V28_L0.9701.00
10_V36_L0.9681.00
20_D216_Y0.9681.00
29_I56_Y0.9671.00
81_I176_I0.9641.00
9_S84_A0.9621.00
179_N201_N0.9551.00
52_I56_Y0.9541.00
99_Y123_D0.9401.00
125_C216_Y0.9381.00
17_A218_H0.9381.00
33_W103_Y0.9351.00
110_A115_L0.9301.00
237_R241_K0.9301.00
46_T49_S0.9271.00
14_L42_N0.9201.00
10_V103_Y0.9201.00
50_V53_A0.9181.00
109_M118_A0.9111.00
55_Y58_E0.9051.00
245_L249_L0.8971.00
234_N237_R0.8941.00
288_Q292_A0.8921.00
194_W198_F0.8841.00
87_K111_L0.8771.00
84_A89_V0.8701.00
189_H192_I0.8681.00
57_A63_V0.8671.00
73_A76_A0.8611.00
76_A79_R0.8571.00
28_L98_V0.8561.00
148_T151_D0.8501.00
114_D172_R0.8461.00
28_L38_I0.8411.00
217_L224_R0.8401.00
24_C27_S0.8391.00
51_E55_Y0.8311.00
125_C129_T0.8291.00
26_E59_N0.8281.00
7_K86_G0.8261.00
26_E29_I0.8171.00
13_P77_R0.8161.00
67_H76_A0.8081.00
105_T109_M0.8071.00
44_G70_N0.8061.00
32_T101_T0.8021.00
43_D71_A0.8011.00
171_Y176_I0.8011.00
71_A79_R0.8001.00
237_R240_I0.7981.00
119_Q169_G0.7951.00
18_G47_D0.7931.00
106_L110_A0.7921.00
105_T208_T0.7831.00
60_Y63_V0.7801.00
24_C96_D0.7761.00
27_S98_V0.7731.00
99_Y102_M0.7721.00
198_F202_A0.7631.00
40_I63_V0.7621.00
25_M63_V0.7581.00
73_A93_D0.7571.00
179_N198_F0.7561.00
39_I83_V0.7521.00
24_C28_L0.7511.00
48_N52_I0.7501.00
37_E84_A0.7461.00
16_N49_S0.7431.00
167_W213_Y0.7351.00
107_M170_V0.7351.00
99_Y212_L0.7341.00
76_A80_G0.7261.00
118_A208_T0.7261.00
21_F49_S0.7241.00
78_N183_F0.7231.00
126_F129_T0.7231.00
166_V169_G0.7201.00
6_N33_W0.7191.00
53_A57_A0.7181.00
115_L204_R0.7181.00
6_N87_K0.7141.00
91_F183_F0.7131.00
113_D204_R0.7121.00
74_S186_G0.7071.00
124_W217_L0.7061.00
175_V202_A0.7041.00
78_N182_K0.7041.00
21_F53_A0.7021.00
17_A73_A0.7021.00
238_H242_I0.6991.00
7_K107_M0.6981.00
202_A205_A0.6981.00
81_I182_K0.6941.00
7_K33_W0.6931.00
175_V179_N0.6931.00
171_Y198_F0.6931.00
39_I80_G0.6931.00
50_V57_A0.6891.00
119_Q207_Y0.6881.00
8_L33_W0.6881.00
71_A185_A0.6871.00
20_D218_H0.6851.00
41_I79_R0.6791.00
36_L62_H0.6781.00
39_I64_R0.6771.00
21_F52_I0.6761.00
78_N185_A0.6761.00
29_I38_I0.6731.00
39_I84_A0.6691.00
118_A170_V0.6671.00
31_Q98_V0.6661.00
172_R175_V0.6641.00
12_I94_A0.6641.00
6_N111_L0.6611.00
238_H241_K0.6591.00
236_Q240_I0.6561.00
36_L85_T0.6531.00
184_I187_L0.6531.00
109_M115_L0.6501.00
178_K203_L0.6481.00
18_G21_F0.6481.00
88_Y107_M0.6471.00
240_I244_R0.6471.00
24_C94_A0.6451.00
18_G49_S0.6431.00
241_K244_R0.6431.00
177_V182_K0.6401.00
10_V90_A0.6381.00
184_I197_E0.6361.00
89_V176_I0.6351.00
32_T100_P0.6341.00
121_N209_E0.6341.00
93_D190_Q0.6341.00
43_D93_D0.6321.00
7_K111_L0.6311.00
17_A24_C0.6301.00
87_K174_D0.6281.00
18_G51_E0.6251.00
121_N211_S0.6231.00
21_F94_A0.6221.00
8_L110_A0.6221.00
107_M110_A0.6221.00
12_I92_V0.6221.00
54_K58_E0.6211.00
7_K36_L0.6161.00
44_G69_A0.6161.00
80_G93_D0.6161.00
27_S97_E0.6151.00
49_S52_I0.6151.00
13_P43_D0.6151.00
29_I36_L0.6081.00
90_A120_C0.6041.00
24_C97_E0.6021.00
17_A93_D0.6021.00
192_I196_T0.6011.00
208_T212_L0.5981.00
175_V201_N0.5961.00
77_R166_V0.5951.00
90_A106_L0.5931.00
56_Y59_N0.5921.00
115_L118_A0.5921.00
67_H71_A0.5901.00
31_Q104_E0.5891.00
11_I91_F0.5891.00
56_Y60_Y0.5891.00
117_V202_A0.5871.00
117_V169_G0.5861.00
225_L228_Q0.5841.00
98_V103_Y0.5841.00
116_D119_Q0.5841.00
13_P93_D0.5831.00
29_I62_H0.5821.00
45_S49_S0.5811.00
57_A60_Y0.5811.00
88_Y172_R0.5811.00
73_A91_F0.5781.00
78_N81_I0.5771.00
164_H195_T0.5761.00
165_V168_M0.5751.00
11_I173_R0.5751.00
24_C98_V0.5741.00
165_V192_I0.5731.00
80_G84_A0.5731.00
166_V195_T0.5721.00
52_I55_Y0.5700.99
36_L60_Y0.5690.99
91_F176_I0.5660.99
44_G67_H0.5650.99
101_T210_Q0.5650.99
234_N238_H0.5630.99
78_N197_E0.5600.99
151_D154_R0.5600.99
164_H168_M0.5580.99
119_Q164_H0.5570.99
24_C95_D0.5540.99
182_K194_W0.5540.99
120_C168_M0.5530.99
122_A168_M0.5510.99
164_H169_G0.5490.99
98_V213_Y0.5460.99
126_F217_L0.5450.99
96_D215_Y0.5440.99
73_A189_H0.5430.99
200_F245_L0.5390.99
150_P153_L0.5390.99
187_L193_V0.5390.99
33_W104_E0.5390.99
243_T247_E0.5380.99
166_V190_Q0.5370.99
150_P154_R0.5370.99
82_E177_V0.5360.99
28_L40_I0.5340.99
90_A168_M0.5330.99
283_D287_R0.5320.99
29_I59_N0.5320.99
218_H222_V0.5310.99
76_A93_D0.5310.99
78_N194_W0.5300.99
241_K245_L0.5300.99
73_A188_H0.5290.99
15_Y43_D0.5280.99
289_R293_E0.5280.99
195_T199_M0.5280.99
164_H192_I0.5270.99
12_I40_I0.5260.99
41_I66_L0.5250.99
222_V225_L0.5240.99
25_M53_A0.5240.99
208_T211_S0.5220.99
43_D77_R0.5200.99
77_R183_F0.5200.99
122_A165_V0.5190.99
94_A215_Y0.5190.99
96_D216_Y0.5190.99
23_T26_E0.5190.99
41_I83_V0.5180.99
87_K173_R0.5180.99
177_V180_N0.5160.99
11_I84_A0.5160.99
156_G159_S0.5150.99
6_N35_A0.5150.99
68_Q76_A0.5130.99
155_M158_S0.5120.99
106_L208_T0.5120.99
22_R59_N0.5120.99
25_M52_I0.5120.99
8_L106_L0.5110.99
15_Y72_G0.5110.99
244_R248_K0.5070.99
53_A63_V0.5060.99
73_A94_A0.5060.99
88_Y111_L0.5050.99
149_G156_G0.5030.99
179_N194_W0.5020.99
153_L157_L0.5010.99
20_D24_C0.5010.99
131_E135_S0.5010.99
180_N197_E0.5000.99
287_R290_M0.5000.99
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3bcvA 2 0.532 100 0.324 Contact Map
3l7iA 4 0.0552 100 0.363 Contact Map
1qg8A 1 0.6337 100 0.378 Contact Map
2z86A 2 0.7355 100 0.38 Contact Map
2d7iA 1 0.939 100 0.394 Contact Map
1xhbA 1 0.936 100 0.395 Contact Map
5ajoA 1 0.9535 100 0.414 Contact Map
4fixA 3 0.968 100 0.482 Contact Map
3ckjA 2 0.7529 100 0.491 Contact Map
4p02A 1 0.9186 100 0.495 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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