GREMLIN Database
DPO3A - DNA polymerase III subunit alpha
UniProt: P10443 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10238
Length: 1160 (1034)
Sequences: 4724 (2817)
Seq/√Len: 87.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
674_K678_E6.1411.00
410_K413_Q5.8421.00
573_N583_P5.4991.00
13_S41_I5.4091.00
152_D191_A4.9311.00
671_E674_K4.1071.00
446_G456_V3.9351.00
1028_V1067_A3.8791.00
92_T126_E3.8731.00
815_D890_R3.8131.00
89_A266_R3.7771.00
30_K33_A3.7561.00
294_K298_E3.5921.00
653_D658_R3.5891.00
704_G726_V3.4681.00
600_L611_L3.3841.00
286_M294_K3.2581.00
89_A165_R3.2401.00
30_K34_L3.2111.00
349_Q353_D3.1901.00
598_D601_Q3.1551.00
302_E375_K3.0161.00
738_A742_M3.0101.00
650_N659_E2.9931.00
585_D588_A2.9791.00
725_S729_E2.9601.00
346_E417_H2.9261.00
729_E733_K2.8911.00
297_K322_D2.8451.00
259_N262_E2.8251.00
147_N150_L2.7891.00
286_M290_D2.7771.00
653_D659_E2.7561.00
852_A859_F2.7401.00
365_G402_F2.7151.00
304_L321_Y2.6831.00
118_R157_F2.6591.00
31_A39_L2.6521.00
1000_V1048_L2.6521.00
717_P721_A2.6491.00
293_V326_E2.6281.00
995_T1051_S2.6151.00
332_I370_V2.6051.00
472_A499_R2.5471.00
565_I774_L2.5041.00
981_R984_D2.4511.00
197_V263_I2.4471.00
55_G548_Y2.4391.00
700_Y723_Q2.4341.00
566_N570_E2.4011.00
28_V57_G2.3691.00
594_K598_D2.3591.00
724_R742_M2.3561.00
139_V166_Y2.3541.00
732_E738_A2.3451.00
293_V297_K2.3441.00
1051_S1069_E2.3241.00
287_S290_D2.2971.00
334_Q394_P2.2931.00
601_Q626_D2.2851.00
395_E703_G2.2741.00
209_D500_K2.2701.00
595_K598_D2.2701.00
225_L448_V2.2671.00
622_R649_D2.2551.00
86_V130_L2.2531.00
289_E333_N2.2431.00
675_P696_V2.2401.00
322_D326_E2.2251.00
596_S777_H2.2181.00
818_S826_N2.1791.00
485_Y496_D2.1731.00
982_L1023_S2.1721.00
600_L605_T2.1661.00
865_L888_F2.1631.00
595_K777_H2.1511.00
293_V333_N2.1471.00
598_D602_R2.1381.00
576_R582_P2.1241.00
604_E807_M2.0881.00
122_I157_F2.0591.00
565_I586_I2.0561.00
746_D749_E2.0431.00
826_N832_V2.0391.00
812_L832_V2.0171.00
441_V501_L2.0141.00
611_L631_M2.0051.00
207_S237_Q1.9971.00
70_F86_V1.9921.00
676_V696_V1.9911.00
30_K206_D1.9851.00
330_Q334_Q1.9821.00
520_T524_D1.9781.00
672_S736_I1.9771.00
699_G734_N1.9711.00
289_E338_P1.9681.00
14_D23_K1.9531.00
350_W414_V1.9501.00
63_K268_N1.9491.00
356_V413_Q1.9481.00
431_I508_A1.9401.00
724_R746_D1.9331.00
643_L648_V1.9331.00
945_P948_V1.9301.00
899_M944_W1.9301.00
852_A855_K1.9291.00
150_L153_E1.9281.00
292_L329_L1.9281.00
326_E330_Q1.9241.00
247_C257_L1.9111.00
297_K326_E1.9081.00
48_C529_Y1.9061.00
810_K830_E1.9031.00
1058_D1061_G1.9011.00
211_D493_A1.8991.00
378_D587_A1.8971.00
247_C258_A1.8801.00
695_Q702_L1.8791.00
272_R275_E1.8771.00
843_E847_E1.8751.00
29_K60_A1.8691.00
576_R778_Y1.8631.00
157_F161_H1.8511.00
131_L197_V1.8501.00
1008_T1014_I1.8461.00
91_N95_Q1.8441.00
728_A742_M1.8401.00
132_S166_Y1.8381.00
155_V194_L1.8331.00
598_D626_D1.8291.00
416_E420_D1.8171.00
742_M746_D1.8121.00
618_D622_R1.8081.00
68_A101_I1.8081.00
894_H943_P1.8071.00
728_A732_E1.8061.00
90_N127_G1.7981.00
418_V556_F1.7971.00
97_L128_L1.7961.00
851_E855_K1.7891.00
296_A325_L1.7841.00
672_S734_N1.7841.00
40_A87_L1.7821.00
724_R749_E1.7811.00
847_E851_E1.7801.00
852_A868_R1.7781.00
601_Q624_Q1.7751.00
165_R266_R1.7741.00
663_Y674_K1.7561.00
632_I762_A1.7541.00
168_L189_A1.7451.00
350_W354_N1.7431.00
186_V196_V1.7311.00
697_L744_I1.7301.00
963_G967_N1.7271.00
25_A56_A1.7251.00
345_M349_Q1.7181.00
56_A60_A1.7181.00
803_E807_M1.7151.00
10_R69_D1.7091.00
284_G291_Y1.7091.00
469_M473_K1.7081.00
1017_C1030_L1.7071.00
159_E194_L1.7041.00
943_P949_V1.7041.00
563_T567_W1.7021.00
22_A205_I1.6991.00
673_L693_I1.6971.00
39_L240_M1.6971.00
443_R457_D1.6961.00
223_F227_D1.6951.00
896_A900_N1.6841.00
7_V261_V1.6761.00
483_E487_A1.6741.00
298_E302_E1.6701.00
304_L369_L1.6661.00
385_D692_Q1.6651.00
237_Q241_R1.6651.00
187_E191_A1.6611.00
226_D450_G1.6601.00
1053_Q1068_R1.6591.00
611_L635_V1.6591.00
861_E935_E1.6521.00
356_V410_K1.6521.00
91_N269_V1.6511.00
88_A269_V1.6481.00
684_I693_I1.6291.00
573_N577_A1.6281.00
31_A240_M1.6271.00
155_V192_R1.6261.00
883_I898_L1.6181.00
864_D868_R1.6171.00
103_K123_E1.6081.00
1050_V1067_A1.6051.00
14_D504_V1.6021.00
169_E199_T1.5861.00
42_T87_L1.5801.00
303_R378_D1.5791.00
457_D461_K1.5791.00
215_I497_M1.5771.00
883_I902_L1.5761.00
575_R781_E1.5711.00
122_I161_H1.5641.00
261_V265_K1.5631.00
694_A708_L1.5631.00
1052_G1065_M1.5571.00
152_D156_A1.5551.00
443_R460_S1.5491.00
596_S776_A1.5471.00
560_R789_A1.5471.00
482_P486_E1.5471.00
288_T339_G1.5451.00
442_I463_I1.5331.00
1028_V1050_V1.5331.00
335_M397_V1.5331.00
299_G373_A1.5281.00
717_P753_G1.5231.00
636_A761_S1.5131.00
619_L634_L1.5131.00
156_A192_R1.5111.00
202_V240_M1.5091.00
333_N338_P1.5081.00
635_V765_A1.5071.00
5_R37_P1.5041.00
200_N241_R1.5041.00
577_A584_L1.5001.00
783_M807_M1.4931.00
295_R298_E1.4891.00
783_M804_C1.4881.00
485_Y495_I1.4800.99
346_E421_M1.4770.99
243_E247_C1.4740.99
32_A60_A1.4680.99
654_R659_E1.4670.99
56_A59_G1.4660.99
409_E567_W1.4650.99
707_M710_R1.4620.99
723_Q726_V1.4520.99
167_F262_E1.4520.99
196_V256_A1.4480.99
973_I997_A1.4450.99
138_D154_C1.4450.99
103_K107_R1.4360.99
131_L169_E1.4260.99
623_L652_I1.4260.99
982_L1026_L1.4250.99
52_K545_D1.4190.99
195_P262_E1.4180.99
300_L373_A1.4180.99
586_I589_I1.4170.99
186_V253_I1.4150.99
568_A785_A1.4150.99
628_F766_L1.4120.99
740_L743_K1.4040.99
280_Q519_P1.4040.99
251_A254_P1.4000.99
719_E723_Q1.4000.99
172_R179_E1.3950.99
23_K26_P1.3930.99
604_E806_R1.3920.99
102_S528_L1.3890.99
591_L766_L1.3850.99
44_F83_H1.3820.99
143_L188_L1.3790.99
297_K300_L1.3790.99
47_L94_Y1.3780.99
34_L242_S1.3780.99
882_L887_A1.3760.99
787_M797_V1.3710.99
472_A476_E1.3710.99
901_S939_A1.3690.99
628_F632_I1.3670.99
607_A786_V1.3650.99
644_Q649_D1.3640.99
663_Y678_E1.3610.99
122_I160_E1.3560.99
85_T133_G1.3560.99
37_P261_V1.3550.99
544_S716_K1.3540.99
590_P769_Y1.3500.99
83_H134_G1.3490.99
241_R249_L1.3460.99
295_R345_M1.3440.99
820_L854_N1.3400.99
595_K776_A1.3340.99
189_A194_L1.3330.99
385_D679_P1.3300.99
599_M776_A1.3200.99
348_I404_V1.3180.99
38_A264_A1.3180.99
626_D655_K1.3170.99
70_F116_I1.3170.99
852_A857_G1.3110.99
577_A583_P1.3110.99
643_L761_S1.3090.99
99_L524_D1.3050.99
643_L649_D1.3040.99
492_K496_D1.2990.99
1000_V1017_C1.2930.99
485_Y492_K1.2920.99
430_I514_G1.2910.99
866_C905_A1.2890.99
1014_I1031_F1.2860.99
654_R657_G1.2860.99
606_T617_K1.2850.99
321_Y382_L1.2790.98
648_V761_S1.2770.98
679_P758_K1.2730.98
77_L107_R1.2720.98
172_R252_D1.2700.98
699_G730_G1.2690.98
854_N857_G1.2690.98
884_M952_G1.2650.98
573_N584_L1.2640.98
215_I445_V1.2630.98
731_A736_I1.2610.98
159_E164_D1.2600.98
148_S187_E1.2600.98
152_D192_R1.2590.98
142_S147_N1.2590.98
25_A59_G1.2590.98
53_F64_P1.2560.98
451_H494_L1.2560.98
321_Y369_L1.2560.98
325_L373_A1.2560.98
838_I885_S1.2520.98
1008_T1032_T1.2450.98
207_S236_P1.2450.98
453_Y457_D1.2450.98
225_L449_L1.2420.98
132_S168_L1.2380.98
224_T450_G1.2380.98
484_I488_D1.2330.98
50_L66_V1.2310.98
262_E266_R1.2290.98
58_H270_T1.2270.98
39_L57_G1.2250.98
576_R781_E1.2230.98
998_G1019_L1.2220.98
262_E265_K1.2210.98
455_F490_E1.2200.98
66_V94_Y1.2190.98
325_L369_L1.2180.98
148_S191_A1.2150.98
27_L202_V1.2130.98
605_T611_L1.2130.98
5_R243_E1.2110.98
561_T782_F1.2080.98
577_A582_P1.2030.98
993_V1068_R1.2010.98
654_R661_I1.1970.98
348_I358_V1.1970.98
300_L325_L1.1950.98
586_I770_Q1.1940.98
1002_A1018_T1.1930.98
568_A774_L1.1920.98
189_A195_P1.1860.98
896_A941_C1.1850.97
28_V60_A1.1830.97
560_R790_D1.1790.97
849_I865_L1.1790.97
852_A869_T1.1760.97
719_E722_K1.1750.97
214_E225_L1.1730.97
7_V38_A1.1720.97
303_R375_K1.1710.97
737_N740_L1.1700.97
167_F266_R1.1700.97
820_L824_H1.1700.97
998_G1028_V1.1690.97
89_A93_G1.1680.97
354_N413_Q1.1660.97
286_M291_Y1.1660.97
47_L98_T1.1660.97
143_L184_A1.1650.97
457_D460_S1.1640.97
92_T127_G1.1640.97
77_L119_D1.1630.97
7_V37_P1.1620.97
1006_M1016_I1.1620.97
88_A128_L1.1620.97
34_L240_M1.1610.97
155_V188_L1.1600.97
44_F134_G1.1600.97
283_T290_D1.1600.97
620_I634_L1.1550.97
178_E182_L1.1490.97
167_F259_N1.1480.97
635_V761_S1.1470.97
159_E193_G1.1470.97
70_F101_I1.1450.97
189_A192_R1.1430.97
823_F833_Y1.1400.97
444_D506_R1.1400.97
818_S858_Y1.1380.97
996_A1019_L1.1370.97
412_D416_E1.1360.97
858_Y868_R1.1310.97
1003_A1017_C1.1300.97
967_N1022_R1.1300.97
821_Y847_E1.1300.97
159_E163_P1.1280.97
129_I167_F1.1250.97
479_P482_P1.1230.97
542_D545_D1.1230.97
684_I747_L1.1200.96
950_L962_T1.1180.96
354_N420_D1.1170.96
327_T330_Q1.1160.96
380_D383_E1.1160.96
379_L762_A1.1160.96
143_L148_S1.1150.96
865_L879_L1.1140.96
90_N93_G1.1140.96
138_D158_Y1.1120.96
1037_K1069_E1.1120.96
1005_V1013_R1.1100.96
221_D231_P1.1100.96
425_D521_K1.1090.96
296_A369_L1.1070.96
19_D44_F1.1070.96
480_Q483_E1.1070.96
446_G494_L1.1070.96
293_V329_L1.1060.96
841_V878_V1.1060.96
664_P743_K1.1040.96
615_G638_F1.1040.96
1047_I1073_I1.1030.96
214_E230_R1.0980.96
24_T56_A1.0970.96
692_Q696_V1.0970.96
19_D134_G1.0960.96
158_Y166_Y1.0960.96
214_E232_R1.0940.96
300_L321_Y1.0890.96
572_I774_L1.0840.96
45_T71_N1.0800.96
46_N105_Y1.0790.96
690_V712_M1.0790.96
700_Y726_V1.0790.96
291_Y295_R1.0770.96
1034_A1038_Y1.0740.96
1017_C1028_V1.0720.95
142_S154_C1.0720.95
431_I529_Y1.0720.95
783_M800_L1.0710.95
146_G180_S1.0700.95
357_P407_C1.0690.95
28_V56_A1.0680.95
475_F495_I1.0680.95
432_T512_A1.0660.95
289_E293_V1.0650.95
593_D777_H1.0640.95
827_D830_E1.0620.95
802_D806_R1.0610.95
428_S539_T1.0610.95
347_F418_V1.0600.95
985_M1054_V1.0600.95
292_L374_L1.0590.95
672_S697_L1.0580.95
495_I499_R1.0580.95
208_S500_K1.0580.95
283_T286_M1.0570.95
702_L710_R1.0560.95
886_G962_T1.0540.95
103_K124_L1.0530.95
1034_A1067_A1.0520.95
481_L495_I1.0490.95
597_F769_Y1.0470.95
36_M243_E1.0460.95
657_G660_E1.0450.95
817_N857_G1.0440.95
168_L194_L1.0430.95
190_E255_E1.0430.95
141_R144_L1.0410.95
721_A749_E1.0410.95
894_H897_A1.0410.95
22_A27_L1.0410.95
71_N83_H1.0410.95
152_D188_L1.0410.95
729_E732_E1.0400.95
816_I865_L1.0400.95
720_M749_E1.0370.95
589_I770_Q1.0360.95
818_S832_V1.0360.95
118_R158_Y1.0350.95
853_R857_G1.0350.95
130_L162_F1.0330.94
635_V768_S1.0310.94
239_Y245_E1.0300.94
1030_L1067_A1.0290.94
989_E992_K1.0250.94
107_R120_W1.0240.94
32_A61_G1.0240.94
611_L765_A1.0240.94
100_L128_L1.0230.94
149_A153_E1.0230.94
672_S696_V1.0220.94
185_A196_V1.0220.94
65_I87_L1.0220.94
96_N127_G1.0210.94
604_E803_E1.0210.94
982_L996_A1.0210.94
170_L253_I1.0200.94
10_R169_E1.0190.94
26_P29_K1.0180.94
184_A187_E1.0180.94
449_L497_M1.0160.94
89_A167_F1.0150.94
69_D83_H1.0110.94
99_L523_T1.0110.94
408_M561_T1.0100.94
170_L256_A1.0100.94
1041_L1072_D1.0090.94
739_E743_K1.0090.94
966_I973_I1.0090.94
650_N683_I1.0070.94
697_L736_I1.0050.94
117_D120_W1.0040.94
242_S245_E1.0020.94
48_C105_Y1.0010.93
697_L731_A1.0010.93
863_F936_Q0.9990.93
599_M602_R0.9990.93
970_L1022_R0.9980.93
606_T800_L0.9950.93
12_H19_D0.9950.93
676_V693_I0.9950.93
438_A502_E0.9940.93
569_L584_L0.9940.93
95_Q524_D0.9940.93
163_P194_L0.9940.93
19_D83_H0.9920.93
23_K504_V0.9900.93
355_G566_N0.9900.93
365_G371_A0.9890.93
1014_I1029_M0.9880.93
600_L635_V0.9870.93
417_H421_M0.9870.93
327_T389_E0.9850.93
86_V128_L0.9840.93
816_I888_F0.9840.93
611_L768_S0.9840.93
996_A1065_M0.9830.93
1048_L1070_V0.9830.93
817_N859_F0.9820.93
118_R138_D0.9760.93
526_A539_T0.9750.93
565_I770_Q0.9740.93
814_P835_I0.9740.93
263_I267_C0.9720.92
25_A60_A0.9720.92
1019_L1050_V0.9710.92
701_T704_G0.9700.92
846_I849_I0.9700.92
619_L652_I0.9690.92
349_Q375_K0.9680.92
26_P209_D0.9680.92
643_L647_M0.9680.92
1015_G1035_L0.9670.92
103_K120_W0.9660.92
603_S638_F0.9630.92
670_H740_L0.9630.92
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164_D266_R0.6230.65
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469_M472_A0.6220.65
50_L541_F0.6220.65
350_W413_Q0.6220.65
378_D770_Q0.6210.65
30_K240_M0.6210.65
1038_Y1041_L0.6210.65
526_A546_V0.6200.64
654_R658_R0.6200.64
430_I513_G0.6200.64
12_H44_F0.6200.64
90_N268_N0.6200.64
108_G114_P0.6180.64
70_F100_L0.6180.64
567_W822_H0.6180.64
1034_A1037_K0.6170.64
703_G707_M0.6170.64
65_I831_I0.6160.64
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997_A1049_I0.6150.64
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180_S184_A0.6140.64
568_A572_I0.6140.64
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219_I448_V0.6130.64
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190_E193_G0.6130.64
1006_M1029_M0.6130.64
717_P720_M0.6130.64
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651_F654_R0.6120.63
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731_A741_A0.6100.63
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950_L960_Y0.6090.63
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946_E968_Q0.6060.63
471_L499_R0.6050.63
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397_V703_G0.5520.56
576_R780_A0.5520.56
539_T546_V0.5510.56
1001_V1025_R0.5510.56
643_L685_L0.5510.56
270_T273_L0.5510.56
700_Y724_R0.5500.55
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991_G1053_Q0.5500.55
293_V322_D0.5500.55
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338_P439_K0.5460.55
564_I800_L0.5460.55
704_G723_Q0.5450.55
896_A942_Q0.5450.55
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301_E322_D0.5450.55
894_H938_Y0.5450.55
132_S169_E0.5450.55
25_A52_K0.5440.55
188_L192_R0.5440.55
568_A767_V0.5440.55
787_M959_L0.5430.54
652_I656_H0.5430.54
1047_I1072_D0.5430.54
865_L869_T0.5420.54
6_F36_M0.5410.54
572_I576_R0.5410.54
960_Y964_H0.5400.54
654_R660_E0.5400.54
131_L199_T0.5400.54
29_K32_A0.5380.54
708_L713_G0.5360.54
273_L549_A0.5360.54
466_D477_A0.5360.54
467_P470_T0.5350.53
608_V776_A0.5350.53
702_L761_S0.5350.53
611_L648_V0.5350.53
27_L31_A0.5340.53
341_F365_G0.5340.53
517_I724_R0.5340.53
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436_M444_D0.5340.53
704_G708_L0.5330.53
72_V158_Y0.5330.53
784_A831_I0.5330.53
173_T178_E0.5320.53
48_C431_I0.5320.53
650_N653_D0.5310.53
70_F104_A0.5310.53
1049_I1071_M0.5310.53
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305_A308_F0.5300.53
516_V825_V0.5300.53
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416_E419_A0.5300.53
1029_M1032_T0.5290.53
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780_A830_E0.5290.53
671_E678_E0.5280.52
418_V517_I0.5280.52
866_C883_I0.5280.52
694_A755_G0.5280.52
897_A940_S0.5280.52
406_F556_F0.5280.52
545_D548_Y0.5270.52
698_S748_V0.5270.52
809_L831_I0.5270.52
369_L382_L0.5270.52
424_R537_P0.5270.52
603_S617_K0.5270.52
531_D534_G0.5270.52
379_L748_V0.5260.52
469_M477_A0.5260.52
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449_L494_L0.5250.52
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761_S765_A0.5250.52
693_I748_V0.5250.52
281_F349_Q0.5250.52
45_T115_I0.5240.52
982_L1052_G0.5240.52
441_V499_R0.5240.52
518_A525_F0.5240.52
23_K216_R0.5230.52
759_S803_E0.5230.52
464_P474_A0.5220.52
497_M500_K0.5220.52
140_G185_A0.5210.51
136_M141_R0.5200.51
947_Q1045_D0.5200.51
483_E486_E0.5200.51
1017_C1048_L0.5190.51
662_S674_K0.5190.51
22_A39_L0.5180.51
10_R19_D0.5160.51
597_F601_Q0.5160.51
257_L260_T0.5150.51
69_D171_I0.5150.51
1019_L1048_L0.5140.51
296_A301_E0.5140.51
458_R462_L0.5140.51
12_H199_T0.5130.50
677_L693_I0.5130.50
590_P766_L0.5130.50
880_E899_M0.5130.50
893_P938_Y0.5130.50
701_T710_R0.5130.50
561_T771_T0.5120.50
670_H737_N0.5120.50
654_R662_S0.5110.50
246_M257_L0.5110.50
985_M994_I0.5110.50
141_R145_R0.5100.50
865_L898_L0.5100.50
212_A441_V0.5100.50
378_D763_A0.5100.50
299_G305_A0.5090.50
433_F542_D0.5080.50
451_H493_A0.5080.50
622_R648_V0.5080.50
9_L15_Y0.5080.50
864_D867_A0.5080.50
137_G140_G0.5080.50
45_T70_F0.5070.50
891_L894_H0.5070.50
301_E306_F0.5070.50
683_I755_G0.5070.50
572_I584_L0.5060.49
1061_G1070_V0.5060.49
748_V753_G0.5060.49
132_S158_Y0.5050.49
174_G237_Q0.5040.49
211_D496_D0.5040.49
139_V881_K0.5040.49
349_Q354_N0.5040.49
1049_I1076_A0.5040.49
176_P180_S0.5030.49
83_H201_D0.5030.49
156_A194_L0.5030.49
600_L631_M0.5030.49
31_A62_I0.5020.49
212_A767_V0.5020.49
819_G832_V0.5020.49
371_A402_F0.5020.49
606_T799_G0.5020.49
392_L418_V0.5020.49
348_I414_V0.5020.49
671_E675_P0.5020.49
426_A518_A0.5020.49
470_T474_A0.5020.49
696_V734_N0.5020.49
300_L304_L0.5020.49
647_M755_G0.5010.49
41_I50_L0.5010.49
439_K462_L0.5000.49
773_W1066_T0.5000.49
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2hnhA 1 0.7802 100 0.247 Contact Map
3f2bA 1 0.6716 100 0.412 Contact Map
4gx8A 1 0.2328 100 0.838 Contact Map
3e38A 4 0.2422 100 0.891 Contact Map
3dcpA 1 0.1836 100 0.935 Contact Map
2yxoA 3 0.1957 99.9 0.94 Contact Map
3b0xA 1 0.1974 99.9 0.946 Contact Map
3o0fA 1 0.1922 99.9 0.947 Contact Map
2w9mA 1 0.1948 99.9 0.947 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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