GREMLIN Database
SECA - Protein translocase subunit SecA
UniProt: P10408 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10936
Length: 901 (793)
Sequences: 3421 (1616)
Seq/√Len: 57.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
53_R58_E5.9441.00
46_K49_E5.6941.00
116_A128_V5.3851.00
443_K472_A5.0441.00
177_G182_Y4.8951.00
28_I88_L4.8311.00
36_E76_K4.6601.00
555_H583_S4.5721.00
262_H281_L4.1041.00
52_A56_K4.0341.00
204_H385_E3.8561.00
38_L46_K3.8001.00
433_E615_G3.7921.00
442_I454_V3.7051.00
29_N85_D3.6821.00
349_W357_V3.5371.00
198_R664_N3.4961.00
35_M70_V3.2131.00
33_P36_E3.1921.00
122_T204_H3.1801.00
751_E760_R3.1391.00
83_H114_L3.0551.00
474_I500_V3.0411.00
443_K447_A3.0181.00
39_S42_E3.0141.00
466_S476_H3.0031.00
477_N486_N2.9761.00
54_L59_V2.9671.00
334_I343_T2.9011.00
685_K736_R2.9011.00
441_D587_Y2.8941.00
54_L121_L2.8571.00
180_N377_F2.8411.00
331_G364_Q2.8331.00
91_G115_P2.8051.00
116_A147_F2.7631.00
244_P317_H2.6991.00
46_K50_F2.6991.00
431_E461_K2.6541.00
423_L583_S2.6251.00
263_F318_A2.6241.00
194_S197_E2.5751.00
53_R66_E2.5501.00
43_L70_V2.5241.00
483_F486_N2.5161.00
41_E44_K2.5151.00
445_R448_K2.4981.00
48_A52_A2.4651.00
50_F70_V2.4611.00
702_D705_G2.4281.00
741_A745_E2.4151.00
446_T475_K2.4071.00
195_P668_D2.4001.00
441_D444_E2.3861.00
395_D398_A2.3741.00
59_V62_N2.3741.00
497_P551_A2.3611.00
24_V92_M2.3611.00
54_L63_L2.3571.00
47_T117_Y2.3391.00
45_G48_A2.3341.00
440_E472_A2.2891.00
327_I343_T2.2821.00
32_E82_R2.2601.00
157_N166_K2.2551.00
81_M84_F2.2381.00
99_I401_F2.2321.00
44_K48_A2.2291.00
446_T498_A2.2091.00
70_V150_L2.1751.00
46_K70_V2.1681.00
760_R763_E2.1621.00
40_D149_F2.1561.00
493_Q496_Y2.1451.00
496_Y519_W2.1231.00
797_K802_E2.1141.00
162_P165_A2.0871.00
78_V146_L2.0841.00
682_D819_K2.0631.00
50_F117_Y2.0541.00
144_R148_E2.0491.00
792_R806_E2.0371.00
81_M146_L2.0251.00
445_R452_V2.0171.00
782_M807_S2.0151.00
445_R450_Q2.0151.00
432_A614_P2.0121.00
747_Y763_E2.0071.00
267_E596_R1.9981.00
79_F146_L1.9971.00
335_I349_W1.9801.00
496_Y518_S1.9611.00
92_M96_E1.9561.00
140_A156_I1.9481.00
737_E741_A1.9471.00
242_I282_I1.9301.00
493_Q518_S1.9201.00
20_R96_E1.9041.00
116_A126_V1.8951.00
119_N386_K1.8911.00
689_D736_R1.8901.00
34_E46_K1.8851.00
21_M89_L1.8701.00
673_S751_E1.8691.00
613_K616_E1.8681.00
496_Y517_G1.8651.00
21_M96_E1.8631.00
601_D604_S1.8601.00
464_L468_E1.8310.99
441_D445_R1.8240.99
556_I575_S1.8220.99
75_S83_H1.8190.99
54_L62_N1.8060.99
148_E154_V1.8010.99
430_T433_E1.7970.99
432_A436_Q1.7950.99
34_E38_L1.7890.99
429_M608_R1.7880.99
21_M92_M1.7850.99
35_M38_L1.7840.99
70_V117_Y1.7700.99
163_A192_A1.7660.99
745_E749_R1.7660.99
240_N244_P1.7660.99
240_N317_H1.7620.99
450_Q583_S1.7590.99
83_H113_T1.7570.99
518_S550_E1.7490.99
127_H384_Y1.7450.99
440_E443_K1.7440.99
681_E744_I1.7360.99
731_H734_T1.7240.99
585_R619_E1.7200.99
691_Y705_G1.7130.99
748_Q752_E1.7020.99
50_F66_E1.7020.99
67_A117_Y1.7010.99
76_K82_R1.6790.99
39_S43_L1.6770.99
436_Q615_G1.6730.99
274_L310_V1.6590.99
50_F63_L1.6570.99
64_I92_M1.6510.99
395_D411_V1.6300.99
60_L95_N1.6220.99
17_T20_R1.6130.99
86_V415_N1.6060.99
192_A198_R1.6060.99
438_I559_T1.6010.99
112_A147_F1.5980.99
681_E740_L1.5980.99
143_N147_F1.5790.98
431_E435_I1.5690.98
239_V310_V1.5660.98
50_F54_L1.5600.98
125_G175_T1.5600.98
24_V65_P1.5490.98
240_N362_G1.5480.98
35_M66_E1.5480.98
129_V182_Y1.5470.98
430_T591_E1.5430.98
124_K385_E1.5420.98
75_S146_L1.5400.98
198_R668_D1.5360.98
327_I336_V1.5340.98
25_V29_N1.5270.98
332_E366_Q1.5190.98
91_G114_L1.5190.98
122_T385_E1.5120.98
444_E448_K1.5110.98
751_E759_M1.4890.98
242_I286_L1.4820.98
116_A174_I1.4820.98
47_T67_A1.4740.98
445_R555_H1.4650.97
124_K204_H1.4580.97
336_V343_T1.4510.97
262_H277_R1.4470.97
93_V412_V1.4400.97
60_L204_H1.4400.97
31_M35_M1.4390.97
208_V387_L1.4350.97
62_N65_P1.4310.97
164_P167_R1.4270.97
47_T50_F1.4200.97
51_R122_T1.4170.97
115_P122_T1.4170.97
446_T452_V1.4160.97
165_A168_E1.4090.97
441_D555_H1.4090.97
647_E804_K1.4030.97
742_Q745_E1.3950.97
680_R743_S1.3940.97
124_K202_K1.3880.96
824_S828_K1.3880.96
266_D269_S1.3850.96
161_M165_A1.3790.96
38_L49_E1.3770.96
449_G497_P1.3750.96
514_V518_S1.3710.96
29_N82_R1.3700.96
837_V840_L1.3640.96
426_L585_R1.3570.96
435_I465_V1.3470.96
51_R121_L1.3460.96
68_F91_G1.3450.96
113_T143_N1.3430.96
42_E45_G1.3400.96
493_Q517_G1.3350.96
145_P148_E1.3340.96
88_L114_L1.3330.95
329_K343_T1.3320.95
477_N499_A1.3300.95
164_P168_E1.3290.95
22_R26_N1.3250.95
448_K452_V1.3230.95
647_E798_D1.3190.95
35_M46_K1.3180.95
161_M166_K1.3050.95
710_L739_I1.3050.95
514_V517_G1.2990.95
74_A78_V1.2960.95
202_K385_E1.2950.95
34_E37_K1.2910.95
270_R325_D1.2900.95
182_Y380_Y1.2890.95
58_E62_N1.2860.95
44_K149_F1.2830.94
95_N119_N1.2790.94
774_L817_S1.2780.94
431_E464_L1.2740.94
590_M603_V1.2740.94
25_V85_D1.2730.94
767_M822_V1.2720.94
621_P625_K1.2690.94
82_R85_D1.2690.94
205_Y388_A1.2670.94
71_V113_T1.2660.94
125_G204_H1.2590.94
32_E76_K1.2570.94
74_A146_L1.2560.94
654_D657_R1.2500.94
54_L122_T1.2490.94
28_I92_M1.2460.94
442_I559_T1.2430.93
120_A152_L1.2410.93
137_Q141_E1.2400.93
334_I345_Q1.2380.93
692_I701_W1.2370.93
605_G609_K1.2360.93
203_L385_E1.2360.93
133_D166_K1.2360.93
141_E148_E1.2270.93
744_I748_Q1.2250.93
177_G200_Q1.2220.93
26_N85_D1.2210.93
444_E447_A1.2210.93
234_E237_K1.2120.93
441_D585_R1.2090.92
686_A819_K1.2080.92
137_Q158_L1.2070.92
477_N483_F1.2060.92
167_R171_A1.2040.92
239_V282_I1.2030.92
247_I261_G1.2030.92
328_V333_V1.2020.92
664_N668_D1.1970.92
781_A810_M1.1940.92
749_R753_V1.1930.92
49_E53_R1.1930.92
26_N30_A1.1900.92
518_S549_L1.1900.92
47_T70_V1.1880.92
688_I736_R1.1860.92
435_I438_I1.1800.92
442_I469_L1.1790.91
98_C408_D1.1790.91
46_K66_E1.1760.91
698_E701_W1.1760.91
75_S78_V1.1750.91
195_P198_R1.1730.91
445_R583_S1.1670.91
245_H285_L1.1630.91
436_Q440_E1.1590.91
662_Q665_E1.1590.91
112_A116_A1.1590.91
491_V556_I1.1560.91
684_F739_I1.1520.91
261_G277_R1.1500.90
446_T551_A1.1500.90
688_I735_L1.1460.90
443_K446_T1.1380.90
75_S81_M1.1370.90
673_S677_N1.1360.90
774_L821_E1.1340.90
282_I310_V1.1330.90
239_V243_I1.1320.90
435_I464_L1.1250.89
129_V208_V1.1250.89
24_V27_I1.1240.89
514_V575_S1.1240.89
441_D583_S1.1220.89
177_G380_Y1.1210.89
436_Q614_P1.1200.89
423_L585_R1.1200.89
676_I767_M1.1200.89
140_A154_V1.1170.89
116_A207_L1.1110.89
711_K717_D1.1110.89
163_A167_R1.1100.89
51_R55_E1.1100.89
113_T147_F1.1050.89
148_E153_T1.1030.89
519_W551_A1.1030.89
29_N32_E1.1010.88
33_P37_K1.0990.88
677_N744_I1.0970.88
45_G49_E1.0950.88
423_L555_H1.0940.88
239_V286_L1.0930.88
321_T324_V1.0920.88
676_I822_V1.0890.88
439_I472_A1.0870.88
685_K689_D1.0860.88
234_E238_R1.0860.88
27_I65_P1.0840.88
235_M309_H1.0800.87
606_M610_L1.0800.87
427_V627_I1.0790.87
30_A65_P1.0780.87
843_Q846_M1.0770.87
839_E842_Q1.0770.87
206_A387_L1.0730.87
61_E95_N1.0720.87
57_G62_N1.0720.87
27_I30_A1.0700.87
28_I31_M1.0670.87
549_L581_A1.0660.87
782_M803_Y1.0660.87
272_V319_L1.0600.86
599_A603_V1.0580.86
324_V776_K1.0560.86
153_T172_A1.0530.86
315_R320_F1.0520.86
770_T825_T1.0500.86
493_Q519_W1.0470.86
673_S763_E1.0430.86
514_V555_H1.0430.86
595_M623_V1.0380.85
622_W625_K1.0320.85
83_H91_G1.0310.85
517_G549_L1.0310.85
476_H500_V1.0300.85
839_E843_Q1.0290.85
625_K629_N1.0290.85
761_H765_G1.0280.85
22_R85_D1.0280.85
657_R661_S1.0260.85
53_R63_L1.0260.85
93_V410_V1.0230.84
436_Q472_A1.0180.84
140_A148_E1.0180.84
618_I623_V1.0170.84
771_L818_L1.0150.84
17_T21_M1.0140.84
448_K583_S1.0140.84
684_F740_L1.0130.84
52_A55_E1.0130.84
75_S84_F1.0130.84
13_R17_T1.0120.84
493_Q514_V1.0090.84
516_G519_W1.0080.84
25_V88_L1.0050.83
34_E66_E1.0040.83
158_L161_M1.0030.83
24_V96_E1.0020.83
110_L113_T1.0010.83
403_S639_F0.9990.83
840_L843_Q0.9980.83
267_E597_I0.9970.83
18_L22_R0.9960.83
89_L92_M0.9950.83
12_S15_D0.9930.83
770_T774_L0.9930.83
142_N154_V0.9930.83
72_R82_R0.9910.82
51_R123_G0.9880.82
71_V150_L0.9850.82
684_F743_S0.9820.82
841_E844_R0.9820.82
270_R324_V0.9770.82
496_Y514_V0.9770.82
200_Q384_Y0.9740.81
738_R742_Q0.9700.81
39_S70_V0.9680.81
159_P166_K0.9660.81
98_C410_V0.9660.81
78_V81_M0.9660.81
31_M66_E0.9650.81
776_K780_A0.9650.81
759_M763_E0.9640.81
229_A232_S0.9630.81
673_S760_R0.9620.81
147_F152_L0.9610.81
71_V146_L0.9590.80
42_E49_E0.9580.80
29_N88_L0.9560.80
25_V28_I0.9560.80
447_A472_A0.9550.80
296_E300_S0.9540.80
515_L518_S0.9530.80
450_Q555_H0.9510.80
402_S408_D0.9480.80
49_E70_V0.9430.79
44_K70_V0.9410.79
5_L9_V0.9410.79
242_I246_L0.9400.79
467_N470_T0.9400.79
659_I814_M0.9390.79
638_N641_I0.9380.79
514_V519_W0.9380.79
485_A489_A0.9370.79
36_E82_R0.9350.79
556_I627_I0.9330.79
320_F349_W0.9330.79
58_E66_E0.9320.78
679_I767_M0.9310.78
557_I583_S0.9310.78
837_V841_E0.9290.78
57_G63_L0.9270.78
71_V83_H0.9240.78
402_S406_K0.9240.78
730_L738_R0.9230.78
13_R408_D0.9230.78
370_Q779_L0.9230.78
457_I559_T0.9200.78
704_P708_E0.9200.78
745_E748_Q0.9200.78
137_Q485_A0.9120.77
676_I763_E0.9110.77
431_E591_E0.9100.77
53_R57_G0.9080.77
92_M95_N0.9060.76
194_S761_H0.9050.76
426_L617_A0.9020.76
9_V12_S0.9020.76
685_K688_I0.9000.76
172_A175_T0.9000.76
519_W549_L0.8980.76
44_K78_V0.8960.76
41_E45_G0.8940.75
809_S813_A0.8940.75
426_L623_V0.8940.75
81_M142_N0.8900.75
841_E845_R0.8900.75
671_D674_E0.8890.75
497_P519_W0.8890.75
666_L771_L0.8880.75
50_F53_R0.8870.75
736_R740_L0.8870.75
299_Y307_M0.8870.75
429_M607_M0.8860.75
155_G172_A0.8860.75
721_A725_D0.8850.75
111_T140_A0.8840.75
306_L788_G0.8840.75
265_V318_A0.8820.74
31_M34_E0.8820.74
320_F357_V0.8820.74
429_M604_S0.8820.74
497_P518_S0.8800.74
270_R319_L0.8800.74
440_E444_E0.8800.74
435_I461_K0.8790.74
773_S821_E0.8780.74
63_L66_E0.8770.74
309_H312_A0.8760.74
676_I747_Y0.8750.74
28_I33_P0.8740.74
207_L388_A0.8720.74
788_G791_L0.8710.74
50_F67_A0.8690.73
48_A56_K0.8670.73
840_L844_R0.8670.73
458_S461_K0.8650.73
34_E49_E0.8630.73
477_N493_Q0.8630.73
242_I285_L0.8620.73
15_D22_R0.8620.73
48_A51_R0.8590.73
817_S821_E0.8590.73
842_Q846_M0.8590.73
7_T12_S0.8570.72
115_P123_G0.8560.72
836_E839_E0.8520.72
233_S367_N0.8520.72
689_D732_E0.8510.72
650_D798_D0.8510.72
28_I64_I0.8490.72
843_Q847_E0.8480.72
31_M88_L0.8480.72
382_R650_D0.8480.72
125_G201_R0.8470.71
751_E756_A0.8450.71
439_I468_E0.8450.71
175_T201_R0.8410.71
169_A175_T0.8380.71
168_E171_A0.8380.71
604_S608_R0.8370.71
21_M93_V0.8370.71
629_N633_K0.8360.70
798_D801_Q0.8350.70
686_A816_E0.8340.70
35_M76_K0.8330.70
462_S502_I0.8310.70
836_E840_L0.8300.70
445_R557_I0.8290.70
280_V284_E0.8280.70
600_S611_G0.8280.70
600_S626_A0.8270.70
790_H793_G0.8260.70
433_E616_E0.8240.69
780_A784_Y0.8240.69
801_Q804_K0.8240.69
436_Q468_E0.8230.69
153_T168_E0.8230.69
323_D327_I0.8200.69
242_I310_V0.8170.69
274_L282_I0.8170.69
641_I645_L0.8160.69
516_G550_E0.8150.68
438_I465_V0.8140.68
838_E842_Q0.8140.68
600_S604_S0.8130.68
103_R333_V0.8130.68
169_A172_A0.8120.68
63_L92_M0.8120.68
680_R827_S0.8110.68
671_D760_R0.8100.68
732_E736_R0.8100.68
387_L407_L0.8090.68
78_V144_R0.8090.68
740_L744_I0.8090.68
370_Q776_K0.8080.68
461_K798_D0.8080.68
837_V842_Q0.8080.68
842_Q845_R0.8070.68
446_T499_A0.8070.68
334_I344_M0.8040.67
489_A493_Q0.8040.67
648_Y790_H0.8040.67
813_A817_S0.7990.67
286_L779_L0.7980.67
103_R411_V0.7960.67
431_E593_A0.7950.67
706_L710_L0.7940.66
200_Q380_Y0.7940.66
496_Y550_E0.7940.66
433_E436_Q0.7900.66
418_M584_S0.7900.66
600_S620_H0.7890.66
792_R802_E0.7880.66
730_L734_T0.7880.66
17_T408_D0.7880.66
399_F403_S0.7870.66
784_Y787_Q0.7860.66
662_Q675_T0.7850.66
691_Y709_R0.7850.66
11_G23_K0.7840.65
835_E840_L0.7840.65
47_T54_L0.7830.65
518_S551_A0.7830.65
291_I303_N0.7820.65
81_M110_L0.7800.65
836_E841_E0.7790.65
46_K117_Y0.7780.65
309_H313_A0.7780.65
424_P620_H0.7780.65
81_M112_A0.7780.65
139_D142_N0.7770.65
191_M372_L0.7750.65
841_E846_M0.7740.64
166_K199_V0.7740.64
182_Y200_Q0.7740.64
279_L297_S0.7720.64
754_V762_F0.7720.64
703_I706_L0.7700.64
65_P92_M0.7690.64
167_R196_E0.7690.64
382_R646_L0.7680.64
414_T418_M0.7680.64
34_E42_E0.7670.64
116_A388_A0.7660.64
719_P722_E0.7660.64
138_R142_N0.7660.64
738_R741_A0.7650.64
202_K664_N0.7640.63
157_N161_M0.7620.63
662_Q771_L0.7620.63
38_L66_E0.7620.63
833_M836_E0.7600.63
436_Q439_I0.7600.63
382_R387_L0.7590.63
840_L847_E0.7580.63
677_N748_Q0.7570.63
692_I735_L0.7550.63
842_Q847_E0.7550.63
144_R154_V0.7540.62
365_I822_V0.7540.62
322_R328_V0.7530.62
687_T706_L0.7530.62
691_Y706_L0.7520.62
609_K621_P0.7510.62
370_Q780_A0.7500.62
285_L306_L0.7500.62
519_W550_E0.7500.62
683_V823_I0.7490.62
681_E737_E0.7480.62
55_E84_F0.7470.62
795_A802_E0.7470.62
626_A629_N0.7460.62
464_L467_N0.7460.62
808_F812_A0.7450.62
6_L10_F0.7440.61
54_L70_V0.7430.61
94_L205_Y0.7420.61
762_F831_V0.7420.61
835_E841_E0.7410.61
39_S44_K0.7390.61
70_V78_V0.7380.61
203_L380_Y0.7360.61
709_R712_N0.7340.60
644_Q647_E0.7340.60
113_T146_L0.7320.60
235_M306_L0.7310.60
692_I732_E0.7290.60
60_L65_P0.7280.60
17_T98_C0.7250.59
604_S614_P0.7240.59
743_S827_S0.7240.59
517_G550_E0.7230.59
735_L739_I0.7230.59
53_R67_A0.7230.59
45_G70_V0.7220.59
419_I581_A0.7210.59
8_K11_G0.7210.59
726_K730_L0.7210.59
433_E613_K0.7190.59
685_K740_L0.7190.59
137_Q808_F0.7180.59
277_R280_V0.7170.59
626_A630_A0.7170.59
31_M65_P0.7170.59
809_S812_A0.7150.58
762_F829_V0.7140.58
687_T709_R0.7140.58
622_W629_N0.7140.58
10_F438_I0.7140.58
688_I732_E0.7130.58
680_R823_I0.7120.58
727_E738_R0.7110.58
421_K583_S0.7100.58
312_A650_D0.7090.58
11_G19_R0.7090.58
49_E63_L0.7080.58
821_E824_S0.7080.58
264_S275_T0.7080.58
260_E264_S0.7060.57
722_E726_K0.7040.57
239_V313_A0.7030.57
11_G15_D0.7020.57
329_K459_I0.7020.57
15_D21_M0.7000.57
61_E64_I0.6970.56
605_G608_R0.6960.56
88_L92_M0.6960.56
449_G498_A0.6940.56
357_V603_V0.6940.56
839_E845_R0.6940.56
466_S474_I0.6940.56
23_K92_M0.6930.56
315_R353_L0.6930.56
404_I639_F0.6930.56
556_I764_K0.6920.56
425_D561_R0.6920.56
610_L618_I0.6920.56
666_L675_T0.6920.56
417_P584_S0.6900.56
446_T449_G0.6900.56
672_V767_M0.6890.56
329_K345_Q0.6890.56
733_E737_E0.6880.55
49_E52_A0.6870.55
590_M607_M0.6860.55
620_H623_V0.6850.55
403_S800_K0.6850.55
78_V149_F0.6850.55
112_A128_V0.6850.55
144_R152_L0.6840.55
701_W705_G0.6830.55
261_G281_L0.6830.55
237_K362_G0.6830.55
192_A664_N0.6820.55
30_A34_E0.6800.55
396_T565_R0.6800.55
706_L739_I0.6790.54
678_S681_E0.6790.54
273_N459_I0.6780.54
243_I311_T0.6770.54
483_F490_I0.6760.54
57_G61_E0.6750.54
763_E826_L0.6750.54
418_M514_V0.6750.54
141_E144_R0.6750.54
432_A591_E0.6750.54
648_Y803_Y0.6730.54
834_P837_V0.6730.54
648_Y800_K0.6720.54
732_E735_L0.6720.54
483_F502_I0.6720.54
332_E667_L0.6710.54
777_E781_A0.6710.54
429_M433_E0.6710.54
43_L149_F0.6700.53
345_Q485_A0.6690.53
467_N471_K0.6690.53
93_V96_E0.6690.53
440_E448_K0.6690.53
243_I282_I0.6680.53
396_T569_N0.6680.53
496_Y549_L0.6680.53
429_M614_P0.6680.53
265_V272_V0.6670.53
462_S480_N0.6670.53
34_E70_V0.6670.53
93_V98_C0.6670.53
47_T53_R0.6660.53
470_T476_H0.6660.53
103_R419_I0.6660.53
466_S478_V0.6660.53
825_T828_K0.6650.53
262_H313_A0.6640.53
142_N514_V0.6640.53
600_S630_A0.6640.53
12_S395_D0.6640.53
321_T325_D0.6600.52
73_E77_R0.6590.52
753_V830_Q0.6590.52
447_A498_A0.6580.52
244_P286_L0.6580.52
259_G264_S0.6580.52
415_N418_M0.6580.52
429_M613_K0.6580.52
816_E819_K0.6580.52
81_M111_T0.6580.52
837_V843_Q0.6580.52
661_S665_E0.6570.52
42_E46_K0.6570.52
707_Q721_A0.6560.52
597_I640_D0.6540.52
840_L845_R0.6530.52
418_M576_G0.6530.52
129_V177_G0.6520.52
116_A153_T0.6520.52
70_V149_F0.6520.52
182_Y377_F0.6520.52
676_I823_I0.6520.52
73_E82_R0.6510.51
111_T419_I0.6510.51
308_H312_A0.6510.51
555_H585_R0.6500.51
677_N681_E0.6500.51
749_R752_E0.6500.51
600_S607_M0.6500.51
450_Q575_S0.6500.51
714_F827_S0.6480.51
718_L739_I0.6480.51
183_G223_L0.6470.51
160_G166_K0.6460.51
84_F146_L0.6460.51
95_N386_K0.6450.51
595_M606_M0.6450.51
688_I823_I0.6440.51
281_L285_L0.6440.51
497_P517_G0.6430.51
436_Q443_K0.6430.51
431_E798_D0.6430.51
265_V319_L0.6420.50
838_E844_R0.6420.50
388_A401_F0.6420.50
163_A166_K0.6410.50
333_V366_Q0.6410.50
144_R300_S0.6400.50
747_Y759_M0.6400.50
687_T691_Y0.6390.50
647_E800_K0.6390.50
599_A623_V0.6390.50
303_N450_Q0.6380.50
455_G571_L0.6380.50
281_L284_E0.6380.50
416_R419_I0.6370.50
157_N199_V0.6360.50
666_L767_M0.6350.50
14_N23_K0.6340.50
837_V845_R0.6330.49
63_L67_A0.6330.49
348_R358_E0.6320.49
111_T147_F0.6320.49
122_T205_Y0.6310.49
58_E63_L0.6310.49
765_G769_Q0.6300.49
103_R418_M0.6280.49
708_E712_N0.6280.49
112_A205_Y0.6280.49
74_A145_P0.6270.49
89_L111_T0.6260.49
59_V122_T0.6260.49
403_S787_Q0.6250.49
133_D338_E0.6250.49
296_E717_D0.6240.48
12_S16_R0.6240.48
54_L58_E0.6240.48
327_I459_I0.6240.48
844_R847_E0.6240.48
496_Y516_G0.6230.48
78_V147_F0.6220.48
443_K474_I0.6210.48
67_A70_V0.6210.48
324_V593_A0.6210.48
680_R744_I0.6210.48
430_T615_G0.6200.48
50_F57_G0.6200.48
166_K268_K0.6190.48
46_K54_L0.6180.48
597_I637_R0.6180.48
333_V363_V0.6180.48
51_R63_L0.6170.48
431_E589_S0.6170.48
243_I314_L0.6150.47
279_L307_M0.6140.47
263_F743_S0.6140.47
707_Q711_K0.6130.47
747_Y751_E0.6120.47
681_E684_F0.6120.47
457_I461_K0.6120.47
766_V825_T0.6120.47
713_D820_Y0.6120.47
466_S500_V0.6110.47
424_P619_E0.6100.47
208_V823_I0.6100.47
282_I285_L0.6080.47
434_K438_I0.6070.47
404_I407_L0.6070.47
430_T614_P0.6070.47
423_L441_D0.6060.46
63_L152_L0.6060.46
662_Q819_K0.6060.46
312_A789_I0.6060.46
243_I318_A0.6060.46
365_I556_I0.6060.46
836_E845_R0.6060.46
32_E85_D0.6050.46
694_P732_E0.6050.46
475_K551_A0.6050.46
449_G551_A0.6050.46
329_K334_I0.6040.46
359_A365_I0.6040.46
243_I317_H0.6030.46
416_R816_E0.6030.46
454_V502_I0.6030.46
96_E410_V0.6030.46
774_L814_M0.6020.46
128_V153_T0.6020.46
460_E503_A0.6010.46
83_H653_N0.6000.46
839_E847_E0.5980.46
276_E365_I0.5980.46
746_V749_R0.5980.46
441_D557_I0.5980.46
708_E711_K0.5970.45
129_V492_A0.5970.45
239_V317_H0.5970.45
282_I291_I0.5970.45
622_W626_A0.5950.45
602_R793_G0.5950.45
345_Q795_A0.5940.45
383_L387_L0.5940.45
774_L818_L0.5940.45
438_I557_I0.5930.45
835_E842_Q0.5920.45
63_L122_T0.5920.45
20_R63_L0.5920.45
247_I281_L0.5920.45
327_I438_I0.5920.45
439_I443_K0.5910.45
237_K241_K0.5910.45
332_E346_G0.5910.45
633_K796_Q0.5910.45
343_T377_F0.5910.45
491_V838_E0.5900.45
308_H351_D0.5900.45
264_S273_N0.5890.45
229_A282_I0.5890.45
76_K314_L0.5880.45
712_N824_S0.5880.45
751_E763_E0.5880.45
33_P76_K0.5870.44
112_A158_L0.5860.44
41_E48_A0.5850.44
11_G89_L0.5850.44
603_V607_M0.5850.44
259_G262_H0.5830.44
681_E685_K0.5830.44
468_E472_A0.5830.44
514_V583_S0.5820.44
369_N503_A0.5820.44
840_L846_M0.5820.44
748_Q751_E0.5820.44
838_E845_R0.5820.44
398_A402_S0.5820.44
230_E233_S0.5810.44
63_L121_L0.5810.44
517_G551_A0.5810.44
53_R59_V0.5810.44
440_E615_G0.5800.44
756_A760_R0.5800.44
747_Y760_R0.5800.44
677_N740_L0.5790.44
75_S110_L0.5790.44
242_I245_H0.5790.44
349_W771_L0.5780.43
489_A624_T0.5780.43
171_A201_R0.5780.43
144_R147_F0.5780.43
629_N632_R0.5770.43
62_N122_T0.5770.43
415_N648_Y0.5770.43
587_Y603_V0.5770.43
175_T204_H0.5760.43
424_P624_T0.5760.43
103_R575_S0.5760.43
264_S271_Q0.5760.43
423_L427_V0.5750.43
834_P842_Q0.5750.43
442_I452_V0.5750.43
637_R641_I0.5740.43
662_Q815_L0.5740.43
99_I211_V0.5740.43
28_I65_P0.5740.43
782_M785_L0.5740.43
591_E604_S0.5740.43
305_M309_H0.5730.43
800_K804_K0.5730.43
71_V144_R0.5730.43
807_S810_M0.5730.43
395_D407_L0.5730.43
834_P838_E0.5720.43
424_P585_R0.5710.43
324_V419_I0.5710.43
111_T457_I0.5710.43
78_V145_P0.5710.43
74_A150_L0.5710.43
83_H150_L0.5710.43
272_V318_A0.5700.43
620_H629_N0.5700.43
18_L21_M0.5690.42
165_A169_A0.5690.42
241_K491_V0.5680.42
28_I89_L0.5680.42
237_K365_I0.5680.42
837_V844_R0.5680.42
216_I442_I0.5670.42
35_M82_R0.5670.42
623_V626_A0.5670.42
23_K96_E0.5660.42
370_Q777_E0.5660.42
75_S80_G0.5660.42
270_R351_D0.5650.42
669_V764_K0.5650.42
11_G16_R0.5650.42
282_I286_L0.5640.42
372_L789_I0.5630.42
14_N411_V0.5620.42
423_L619_E0.5620.42
149_F152_L0.5620.42
166_K664_N0.5610.42
590_M599_A0.5610.42
370_Q783_D0.5600.41
709_R713_D0.5590.41
377_F380_Y0.5590.41
432_A464_L0.5580.41
419_I549_L0.5580.41
286_L310_V0.5570.41
639_F643_K0.5570.41
613_K617_A0.5570.41
75_S113_T0.5570.41
201_R380_Y0.5570.41
322_R333_V0.5560.41
70_V74_A0.5560.41
208_V401_F0.5550.41
605_G611_G0.5550.41
699_E731_H0.5550.41
42_E70_V0.5550.41
20_R137_Q0.5540.41
818_L822_V0.5540.41
208_V380_Y0.5540.41
335_I354_H0.5530.41
100_A416_R0.5530.41
430_T611_G0.5520.41
766_V831_V0.5520.41
103_R414_T0.5520.41
659_I815_L0.5520.41
238_R241_K0.5510.41
683_V820_Y0.5510.41
8_K822_V0.5510.41
576_G584_S0.5510.41
142_N145_P0.5500.40
758_M836_E0.5500.40
555_H776_K0.5500.40
839_E844_R0.5500.40
718_L742_Q0.5500.40
13_R395_D0.5480.40
102_M376_T0.5480.40
496_Y551_A0.5480.40
349_W793_G0.5470.40
76_K80_G0.5470.40
75_S82_R0.5460.40
54_L117_Y0.5460.40
270_R782_M0.5450.40
836_E846_M0.5450.40
679_I822_V0.5450.40
404_I643_K0.5450.40
53_R117_Y0.5450.40
374_S786_R0.5440.40
300_S339_H0.5440.40
754_V832_R0.5440.40
296_E303_N0.5430.40
93_V609_K0.5430.40
421_K426_L0.5430.40
752_E756_A0.5420.40
727_E730_L0.5420.40
721_A726_K0.5420.40
22_R89_L0.5420.40
243_I313_A0.5410.39
366_Q662_Q0.5410.39
790_H828_K0.5410.39
616_E633_K0.5400.39
68_F92_M0.5400.39
658_A662_Q0.5400.39
789_I802_E0.5400.39
822_V826_L0.5400.39
284_E290_G0.5390.39
243_I812_A0.5390.39
711_K716_L0.5390.39
266_D650_D0.5390.39
792_R795_A0.5380.39
364_Q468_E0.5380.39
72_R78_V0.5380.39
143_N409_T0.5380.39
562_H567_I0.5380.39
766_V770_T0.5370.39
747_Y821_E0.5370.39
76_K85_D0.5360.39
835_E839_E0.5360.39
601_D608_R0.5360.39
784_Y793_G0.5350.39
835_E844_R0.5350.39
754_V759_M0.5340.39
838_E847_E0.5330.39
266_D450_Q0.5330.39
786_R831_V0.5330.39
601_D789_I0.5330.39
836_E842_Q0.5330.39
18_L89_L0.5320.39
19_R159_P0.5320.39
603_V608_R0.5320.39
114_L146_L0.5310.38
270_R320_F0.5300.38
92_M388_A0.5300.38
755_G758_M0.5300.38
590_M600_S0.5290.38
47_T51_R0.5290.38
483_F658_A0.5290.38
95_N118_L0.5280.38
373_A660_Y0.5280.38
332_E345_Q0.5280.38
181_E188_R0.5280.38
268_K597_I0.5270.38
168_E172_A0.5270.38
157_N177_G0.5270.38
57_G70_V0.5270.38
369_N398_A0.5270.38
46_K63_L0.5260.38
683_V819_K0.5260.38
398_A780_A0.5260.38
499_A648_Y0.5250.38
414_T584_S0.5250.38
133_D162_P0.5250.38
324_V460_E0.5250.38
72_R75_S0.5250.38
273_N450_Q0.5250.38
684_F688_I0.5240.38
837_V846_M0.5240.38
36_E75_S0.5240.38
483_F556_I0.5240.38
714_F743_S0.5230.38
111_T458_S0.5220.37
89_L96_E0.5220.37
41_E56_K0.5210.37
38_L50_F0.5210.37
450_Q557_I0.5200.37
704_P722_E0.5200.37
607_M623_V0.5200.37
323_D343_T0.5200.37
762_F827_S0.5190.37
84_F556_I0.5190.37
657_R815_L0.5190.37
63_L70_V0.5190.37
505_N562_H0.5190.37
395_D402_S0.5180.37
731_H735_L0.5180.37
447_A682_D0.5170.37
434_K560_E0.5170.37
397_E565_R0.5170.37
91_G113_T0.5170.37
17_T410_V0.5170.37
10_F13_R0.5150.37
159_P377_F0.5150.37
44_K52_A0.5150.37
363_V491_V0.5150.37
211_V634_V0.5150.37
643_K647_E0.5150.37
18_L620_H0.5150.37
470_T473_G0.5140.37
379_N649_D0.5140.37
568_D571_L0.5140.37
51_R115_P0.5140.37
29_N72_R0.5130.37
581_A807_S0.5130.37
93_V414_T0.5120.36
291_I306_L0.5120.36
324_V797_K0.5120.36
168_E741_A0.5120.36
169_A633_K0.5120.36
31_M72_R0.5120.36
275_T610_L0.5110.36
218_E347_R0.5110.36
357_V599_A0.5110.36
286_L306_L0.5100.36
737_E740_L0.5100.36
841_E847_E0.5100.36
741_A744_I0.5100.36
195_P664_N0.5100.36
233_S459_I0.5100.36
272_V310_V0.5100.36
603_V618_I0.5100.36
417_P452_V0.5100.36
133_D735_L0.5080.36
103_R569_N0.5080.36
5_L721_A0.5080.36
375_I812_A0.5080.36
240_N282_I0.5070.36
23_K345_Q0.5060.36
375_I610_L0.5060.36
111_T157_N0.5060.36
318_A556_I0.5060.36
120_A126_V0.5060.36
203_L556_I0.5060.36
836_E844_R0.5060.36
493_Q549_L0.5050.36
455_G562_H0.5050.36
195_P427_V0.5050.36
45_G50_F0.5040.36
236_Y313_A0.5040.36
50_F58_E0.5030.36
446_T474_I0.5030.36
664_N790_H0.5030.36
245_H282_I0.5030.36
92_M114_L0.5020.35
198_R800_K0.5020.35
715_D718_L0.5020.35
327_I369_N0.5020.35
29_N76_K0.5010.35
59_V63_L0.5010.35
682_D685_K0.5010.35
825_T829_V0.5010.35
275_T465_V0.5000.35
362_G497_P0.5000.35
129_V478_V0.5000.35
590_M606_M0.5000.35
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1nktA 3 0.8901 100 0.078 Contact Map
2ipcA 2 0.9101 100 0.249 Contact Map
1tf5A 1 0.8602 100 0.362 Contact Map
2fsfA 2 0.8047 100 0.366 Contact Map
4ys0A 1 0.8479 100 0.448 Contact Map
2eyqA 1 0.6138 100 0.875 Contact Map
4ljyA 1 0.4606 100 0.881 Contact Map
4nhoA 1 0.4595 100 0.895 Contact Map
4a2wA 1 0.5705 100 0.901 Contact Map
4w7sA 2 0.4628 100 0.904 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0187 seconds.