ENTE - ECOLI - GREMLIN Contacts

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ENTE - Enterobactin synthase component E

UniProt:	P10378	Sequences: MSIPFTRWPEEFARRYREKGYWQDLPLTDILTRHAASDSIAVIDGERQLSYRELNQAADNLACSLRRQGIKPGETALVQLGNVAELYITFFALLKLGVAPVLALFSHQRSELNAYASQIEPALLIADRQHALFSGDDFLNTFVTEHSSIRVVQLLNDSGEHNLQDAINHPAEDFTATPSPADEVAYFQLSGGTTGTPKLIPRTHNDYYYSVRRSVEICQFTQQTRYLCAIPAAHNYAMSSPGSLGVFLAGGTVVLAADPSATLCFPLIEKHQVNVTALVPPAVSLWLQALIEGESRAQLASLKLLQVGGARLSATLAARIPAEIGCQLQQVFGMAEGLVNYTRLDDSAEKIIHTQGYPMCPDDEVWVADAEGNPLPQGEVGRLMTRGPYTFRGYYKSPQHNASAFDANGFYCSGDLISIDPEGYITVQGREKDQINRGGEKIAAEEIENLLLRHPAVIYAALVSMEDELMGEKSCAYLVVKEPLRAVQVRRFLREQGIAEFKLPDRVECVDSLPLTAVGKVDKKQLRQWLASRASA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10263
Length:	536 (480)
Sequences:	71696 (51779)
Seq/√Len:	2363.4

ECOLI - ENTE ENTF AAS LCFA ACSA FADK PRPE CAIC MENE PAAK
BACSU - PPSE SRFAC DHBE ACSA LCFA LCFB YNGI YDAB PPSC PPSB YTCI MENE YHFT DLTA DHBF PKSJ PPSD PPSA SRFAA SRFAB PKSN
HALSA - Q9HRY8 Q9HSM3 Q9HQU8 Q9HNK0 Q9HQ43 Q9HQN8
SULSO - Q97UX8 Q97WQ0 Q97UW7 Q97YK9 Q97VU7 Q97U22 Q97VT6 Q97WQ9 Q97WK0 Q97XW4 Q97UF6 Q97V27 Q97WS5 Q980E4 Q97X52 Q97XW5 Q97VJ6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
184_V	201_P	3.843	1.00
454_H	492_F	3.176	1.00
383_L	417_I	3.024	1.00
59_D	95_K	2.924	1.00
364_E	386_R	2.893	1.00
397_S	400_H	2.850	1.00
77_L	121_P	2.796	1.00
74_E	122_A	2.765	1.00
203_T	392_R	2.764	1.00
118_Q	189_L	2.750	1.00
55_N	95_K	2.732	1.00
418_S	426_T	2.732	1.00
70_I	98_V	2.667	1.00
43_I	252_T	2.663	1.00
382_R	412_C	2.495	1.00
225_R	252_T	2.449	1.00
40_I	48_Q	2.399	1.00
120_E	396_K	2.384	1.00
64_S	68_Q	2.369	1.00
436_N	441_K	2.353	1.00
459_Y	515_L	2.323	1.00
452_L	460_A	2.305	1.00
75_T	101_V	2.259	1.00
32_T	55_N	2.254	1.00
368_A	384_M	2.239	1.00
451_L	476_A	2.235	1.00
366_W	374_P	2.222	1.00
57_A	88_I	2.197	1.00
114_A	196_T	2.185	1.00
420_D	426_T	2.156	1.00
380_V	416_L	2.149	1.00
384_M	412_C	2.145	1.00
369_D	373_N	2.131	1.00
118_Q	397_S	2.129	1.00
89_T	125_I	2.128	1.00
522_D	525_Q	2.113	1.00
55_N	59_D	2.105	1.00
266_P	270_K	2.042	1.00
433_D	523_K	2.042	1.00
475_C	508_E	2.042	1.00
400_H	403_S	2.041	1.00
44_D	84_A	2.025	1.00
93_L	98_V	2.021	1.00
180_P	183_E	1.998	1.00
224_T	303_K	1.979	1.00
418_S	428_Q	1.969	1.00
453_R	497_G	1.958	1.00
398_P	402_A	1.950	1.00
354_T	426_T	1.913	1.00
43_I	48_Q	1.900	1.00
151_V	155_L	1.897	1.00
420_D	424_Y	1.885	1.00
314_A	318_A	1.884	1.00
113_N	117_S	1.884	1.00
61_L	88_I	1.864	1.00
72_P	183_E	1.850	1.00
38_D	52_R	1.849	1.00
224_T	274_N	1.847	1.00
366_W	384_M	1.834	1.00
71_K	74_E	1.816	1.00
66_R	96_L	1.780	1.00
43_I	271_H	1.777	1.00
73_G	183_E	1.744	1.00
525_Q	528_Q	1.741	1.00
458_I	481_K	1.730	1.00
419_I	425_I	1.729	1.00
52_R	56_Q	1.717	1.00
58_A	95_K	1.715	1.00
446_E	502_K	1.715	1.00
380_V	428_Q	1.704	1.00
452_L	459_Y	1.679	1.00
50_S	53_E	1.665	1.00
448_E	462_L	1.657	1.00
463_V	477_Y	1.649	1.00
81_G	127_D	1.646	1.00
254_V	273_V	1.645	1.00
437_R	442_I	1.644	1.00
272_Q	301_S	1.622	1.00
377_Q	419_I	1.620	1.00
87_Y	243_S	1.615	1.00
122_A	150_R	1.606	1.00
203_T	206_D	1.599	1.00
478_L	509_C	1.581	1.00
215_V	249_A	1.560	1.00
75_T	99_A	1.559	1.00
77_L	103_A	1.551	1.00
184_V	392_R	1.551	1.00
94_L	185_A	1.548	1.00
477_Y	526_L	1.544	1.00
462_L	476_A	1.541	1.00
37_S	52_R	1.537	1.00
399_Q	403_S	1.534	1.00
49_L	88_I	1.529	1.00
479_V	513_L	1.528	1.00
480_V	509_C	1.522	1.00
341_Y	385_T	1.520	1.00
263_L	266_P	1.520	1.00
278_L	283_V	1.519	1.00
64_S	166_A	1.493	1.00
466_E	472_E	1.491	1.00
450_L	497_G	1.491	1.00
216_E	361_P	1.477	1.00
456_A	488_Q	1.474	1.00
189_L	199_L	1.473	1.00
367_V	417_I	1.468	1.00
40_I	43_I	1.468	1.00
182_D	205_N	1.450	1.00
76_A	93_L	1.447	1.00
40_I	252_T	1.436	1.00
246_V	251_G	1.435	1.00
487_V	491_R	1.433	1.00
187_F	395_Y	1.430	1.00
490_R	507_V	1.424	1.00
376_P	379_E	1.424	1.00
201_P	395_Y	1.420	1.00
492_F	497_G	1.417	1.00
327_Q	345_D	1.412	1.00
59_D	63_C	1.410	1.00
269_E	297_A	1.409	1.00
119_I	189_L	1.406	1.00
351_I	422_E	1.406	1.00
334_M	411_Y	1.404	1.00
227_L	273_V	1.400	1.00
39_S	223_Q	1.398	1.00
318_A	322_A	1.396	1.00
260_S	263_L	1.395	1.00
49_L	84_A	1.394	1.00
35_A	55_N	1.393	1.00
116_A	121_P	1.391	1.00
490_R	494_R	1.383	1.00
32_T	95_K	1.381	1.00
417_I	427_V	1.378	1.00
516_T	522_D	1.375	1.00
281_P	310_A	1.368	1.00
225_R	254_V	1.367	1.00
221_T	224_T	1.362	1.00
342_T	365_V	1.362	1.00
181_A	205_N	1.360	1.00
77_L	116_A	1.356	1.00
206_D	338_L	1.356	1.00
201_P	393_G	1.355	1.00
416_L	431_E	1.355	1.00
44_D	47_R	1.354	1.00
369_D	375_L	1.354	1.00
478_L	507_V	1.351	1.00
267_L	271_H	1.347	1.00
380_V	418_S	1.342	1.00
101_V	119_I	1.341	1.00
391_F	405_F	1.335	1.00
61_L	92_A	1.322	1.00
76_A	98_V	1.322	1.00
224_T	275_V	1.319	1.00
357_Y	424_Y	1.317	1.00
386_R	410_F	1.308	1.00
67_R	170_P	1.302	1.00
491_R	495_E	1.301	1.00
477_Y	510_V	1.299	1.00
283_V	305_L	1.297	1.00
365_V	385_T	1.295	1.00
256_A	267_L	1.294	1.00
351_I	424_Y	1.291	1.00
41_A	54_L	1.289	1.00
459_Y	479_V	1.288	1.00
75_T	187_F	1.287	1.00
205_N	388_P	1.285	1.00
475_C	506_R	1.284	1.00
404_A	411_Y	1.281	1.00
91_F	247_F	1.279	1.00
467_D	473_K	1.266	1.00
486_A	509_C	1.260	1.00
118_Q	396_K	1.256	1.00
494_R	503_L	1.251	1.00
70_I	74_E	1.247	1.00
118_Q	196_T	1.244	1.00
201_P	392_R	1.243	1.00
465_M	475_C	1.243	1.00
485_R	488_Q	1.240	1.00
435_I	444_A	1.237	1.00
307_V	312_L	1.236	1.00
73_G	392_R	1.235	1.00
366_W	410_F	1.234	1.00
358_P	365_V	1.229	1.00
57_A	60_N	1.227	1.00
114_A	118_Q	1.227	1.00
99_A	184_V	1.219	1.00
225_R	273_V	1.216	1.00
464_S	472_E	1.213	1.00
75_T	395_Y	1.208	1.00
344_L	424_Y	1.206	1.00
276_T	302_L	1.205	1.00
445_E	449_N	1.200	1.00
109_R	113_N	1.194	1.00
492_F	495_E	1.194	1.00
382_R	431_E	1.187	1.00
78_V	89_T	1.184	1.00
70_I	76_A	1.182	1.00
187_F	199_L	1.171	1.00
473_K	505_D	1.171	1.00
370_A	431_E	1.170	1.00
494_R	500_E	1.169	1.00
440_E	501_F	1.169	1.00
47_R	84_A	1.166	1.00
55_N	174_F	1.160	1.00
433_D	445_E	1.158	1.00
275_V	304_L	1.157	1.00
56_Q	60_N	1.155	1.00
179_S	183_E	1.148	1.00
109_R	133_F	1.146	1.00
486_A	490_R	1.140	1.00
54_L	91_F	1.140	1.00
375_L	379_E	1.134	1.00
48_Q	271_H	1.134	1.00
284_S	316_L	1.130	1.00
320_I	324_I	1.125	1.00
288_Q	319_R	1.123	1.00
41_A	51_Y	1.121	1.00
79_Q	112_L	1.115	1.00
383_L	427_V	1.115	1.00
477_Y	527_R	1.103	1.00
473_K	506_R	1.098	1.00
49_L	57_A	1.097	1.00
262_T	289_A	1.097	1.00
113_N	145_E	1.094	1.00
486_A	507_V	1.093	1.00
117_S	196_T	1.093	1.00
43_I	254_V	1.091	1.00
182_D	203_T	1.091	1.00
480_V	484_L	1.087	1.00
57_A	85_E	1.084	1.00
92_A	96_L	1.084	1.00
64_S	67_R	1.084	1.00
476_A	507_V	1.083	1.00
268_I	301_S	1.082	1.00
70_I	123_L	1.081	1.00
287_L	319_R	1.078	1.00
53_E	56_Q	1.072	1.00
254_V	271_H	1.071	1.00
400_H	404_A	1.067	1.00
68_Q	150_R	1.067	1.00
202_R	206_D	1.067	1.00
64_S	170_P	1.063	1.00
54_L	88_I	1.060	1.00
190_S	200_I	1.056	1.00
450_L	453_R	1.053	1.00
62_A	95_K	1.051	1.00
103_A	112_L	1.050	1.00
313_S	316_L	1.042	1.00
363_D	389_Y	1.041	1.00
458_I	479_V	1.041	1.00
32_T	59_D	1.038	1.00
510_V	529_W	1.037	1.00
86_L	232_A	1.037	1.00
454_H	489_V	1.036	1.00
225_R	274_N	1.036	1.00
510_V	513_L	1.034	1.00
434_Q	443_A	1.033	1.00
465_M	506_R	1.032	1.00
438_G	470_M	1.027	1.00
355_Q	427_V	1.024	1.00
45_G	257_A	1.021	1.00
254_V	267_L	1.021	1.00
206_D	390_T	1.013	1.00
61_L	125_I	1.013	1.00
74_E	98_V	1.012	1.00
319_R	323_E	1.011	1.00
384_M	410_F	1.008	1.00
128_R	156_N	1.005	1.00
385_T	413_S	1.003	1.00
110_S	497_G	1.000	1.00
56_Q	172_E	1.000	1.00
448_E	523_K	0.999	1.00
226_Y	246_V	0.999	1.00
493_L	503_L	0.997	1.00
49_L	54_L	0.994	1.00
491_R	494_R	0.993	1.00
513_L	521_V	0.989	1.00
342_T	425_I	0.987	1.00
525_Q	529_W	0.982	1.00
315_T	319_R	0.982	1.00
354_T	424_Y	0.979	1.00
488_Q	491_R	0.973	1.00
224_T	251_G	0.972	1.00
200_I	391_F	0.971	1.00
285_L	469_L	0.970	1.00
39_S	252_T	0.970	1.00
75_T	120_E	0.965	1.00
461_A	513_L	0.964	1.00
344_L	354_T	0.963	1.00
524_K	528_Q	0.962	1.00
40_I	50_S	0.960	1.00
386_R	408_N	0.960	1.00
42_V	87_Y	0.956	1.00
58_A	92_A	0.955	1.00
499_A	502_K	0.950	1.00
191_G	518_V	0.946	1.00
111_E	502_K	0.945	1.00
107_H	115_Y	0.942	1.00
209_Y	362_D	0.936	1.00
454_H	488_Q	0.936	1.00
114_A	117_S	0.936	1.00
61_L	89_T	0.935	1.00
387_G	390_T	0.935	1.00
435_I	474_S	0.934	1.00
450_L	493_L	0.932	1.00
80_L	83_V	0.929	1.00
365_V	425_I	0.926	1.00
284_S	313_S	0.925	1.00
110_S	114_A	0.925	1.00
188_Q	335_A	0.923	1.00
104_L	233_A	0.922	1.00
209_Y	388_P	0.920	1.00
110_S	113_N	0.920	1.00
406_D	412_C	0.919	1.00
367_V	375_L	0.917	1.00
63_C	171_A	0.917	1.00
312_L	317_A	0.914	1.00
127_D	130_H	0.913	1.00
227_L	256_A	0.909	1.00
90_F	100_P	0.907	1.00
31_L	35_A	0.906	1.00
114_A	189_L	0.905	1.00
32_T	36_A	0.904	1.00
77_L	124_L	0.903	1.00
65_L	93_L	0.896	1.00
369_D	379_E	0.895	1.00
84_A	88_I	0.893	1.00
211_V	248_L	0.887	1.00
304_L	329_Q	0.885	1.00
488_Q	492_F	0.883	1.00
47_R	57_A	0.882	1.00
283_V	320_I	0.879	1.00
210_S	339_V	0.878	1.00
365_V	383_L	0.878	1.00
66_R	175_T	0.878	1.00
416_L	429_G	0.876	1.00
66_R	71_K	0.875	1.00
367_V	425_I	0.875	1.00
63_C	66_R	0.874	1.00
246_V	253_V	0.872	1.00
351_I	420_D	0.871	1.00
372_G	384_M	0.871	1.00
54_L	58_A	0.871	1.00
202_R	338_L	0.868	1.00
81_G	129_Q	0.866	1.00
85_E	88_I	0.865	1.00
453_R	492_F	0.863	1.00
78_V	100_P	0.860	1.00
466_E	469_L	0.860	1.00
319_R	322_A	0.858	1.00
43_I	225_R	0.855	1.00
128_R	155_L	0.855	1.00
53_E	57_A	0.854	1.00
306_Q	331_V	0.851	1.00
65_L	125_I	0.847	1.00
62_A	96_L	0.846	1.00
30_I	34_H	0.842	1.00
277_A	340_N	0.836	1.00
29_D	32_T	0.835	1.00
223_Q	274_N	0.831	1.00
202_R	391_F	0.828	1.00
437_R	464_S	0.827	1.00
269_E	298_Q	0.824	1.00
87_Y	255_L	0.823	1.00
93_L	100_P	0.822	1.00
114_A	397_S	0.822	1.00
46_E	270_K	0.820	1.00
147_S	150_R	0.819	1.00
399_Q	402_A	0.818	1.00
63_C	175_T	0.814	1.00
28_T	179_S	0.813	1.00
70_I	96_L	0.804	1.00
290_L	294_E	0.804	1.00
437_R	505_D	0.804	1.00
57_A	84_A	0.803	1.00
55_N	58_A	0.802	1.00
274_N	303_K	0.802	1.00
42_V	84_A	0.801	1.00
77_L	101_V	0.800	1.00
185_A	204_H	0.799	1.00
378_G	421_P	0.799	1.00
30_I	212_R	0.799	1.00
40_I	44_D	0.798	1.00
461_A	526_L	0.794	1.00
90_F	238_M	0.792	1.00
33_R	36_A	0.787	1.00
370_A	382_R	0.784	1.00
88_I	92_A	0.783	1.00
304_L	327_Q	0.782	1.00
283_V	307_V	0.780	1.00
225_R	272_Q	0.778	1.00
489_V	507_V	0.777	1.00
337_G	390_T	0.777	1.00
229_A	282_A	0.776	1.00
383_L	425_I	0.776	1.00
433_D	448_E	0.774	1.00
117_S	148_S	0.773	1.00
479_V	512_S	0.773	1.00
146_H	149_I	0.767	1.00
456_A	481_K	0.766	1.00
297_A	300_A	0.766	1.00
262_T	266_P	0.762	1.00
364_E	410_F	0.761	1.00
60_N	171_A	0.758	1.00
90_F	94_L	0.757	1.00
279_V	282_A	0.757	1.00
68_Q	123_L	0.755	1.00
284_S	319_R	0.753	1.00
39_S	222_Q	0.750	1.00
401_N	405_F	0.749	1.00
63_C	173_D	0.749	1.00
284_S	288_Q	0.748	1.00
417_I	425_I	0.746	1.00
337_G	411_Y	0.745	1.00
47_R	85_E	0.741	1.00
220_F	275_V	0.741	1.00
461_A	521_V	0.741	1.00
365_V	417_I	0.740	1.00
185_A	207_Y	0.738	1.00
386_R	409_G	0.738	1.00
60_N	64_S	0.735	1.00
31_L	55_N	0.734	1.00
487_V	490_R	0.734	1.00
93_L	96_L	0.733	1.00
215_V	245_G	0.733	1.00
451_L	460_A	0.732	1.00
54_L	87_Y	0.731	1.00
366_W	386_R	0.731	1.00
60_N	172_E	0.728	1.00
101_V	121_P	0.728	1.00
184_V	203_T	0.727	1.00
186_Y	202_R	0.727	1.00
490_R	503_L	0.727	1.00
263_L	267_L	0.726	1.00
179_S	204_H	0.725	1.00
210_S	338_L	0.725	1.00
88_I	163_L	0.725	1.00
407_A	412_C	0.722	1.00
458_I	480_V	0.722	1.00
337_G	341_Y	0.721	1.00
29_D	33_R	0.721	1.00
500_E	503_L	0.720	1.00
28_T	32_T	0.720	1.00
266_P	269_E	0.720	1.00
368_A	374_P	0.719	1.00
397_S	401_N	0.718	1.00
83_V	127_D	0.718	1.00
268_I	273_V	0.717	1.00
337_G	385_T	0.717	1.00
80_L	86_L	0.716	1.00
115_Y	199_L	0.713	1.00
38_D	50_S	0.712	1.00
380_V	431_E	0.712	1.00
405_F	412_C	0.711	1.00
80_L	155_L	0.711	1.00
465_M	473_K	0.711	1.00
48_Q	252_T	0.710	1.00
28_T	94_L	0.710	1.00
329_Q	345_D	0.709	1.00
110_S	196_T	0.708	1.00
456_A	480_V	0.706	1.00
466_E	470_M	0.706	1.00
315_T	318_A	0.706	1.00
412_C	431_E	0.705	1.00
331_V	340_N	0.703	1.00
79_Q	124_L	0.700	1.00
71_K	98_V	0.699	1.00
477_Y	529_W	0.696	1.00
377_Q	421_P	0.695	1.00
437_R	474_S	0.695	1.00
221_T	303_K	0.693	1.00
277_A	331_V	0.692	1.00
445_E	448_E	0.692	1.00
28_T	204_H	0.691	1.00
123_L	151_V	0.690	1.00
89_T	93_L	0.689	1.00
466_E	471_G	0.689	1.00
77_L	119_I	0.686	1.00
31_L	91_F	0.684	1.00
76_A	123_L	0.684	1.00
493_L	498_I	0.683	1.00
302_L	305_L	0.681	1.00
312_L	328_L	0.680	1.00
150_R	153_Q	0.680	1.00
61_L	65_L	0.678	1.00
79_Q	130_H	0.677	1.00
61_L	64_S	0.676	1.00
63_C	170_P	0.674	1.00
238_M	277_A	0.673	1.00
227_L	267_L	0.673	1.00
259_P	282_A	0.671	1.00
228_C	242_G	0.670	1.00
450_L	492_F	0.667	1.00
486_A	506_R	0.666	1.00
90_F	244_L	0.666	1.00
66_R	177_T	0.665	1.00
71_K	122_A	0.665	1.00
68_Q	151_V	0.664	1.00
226_Y	275_V	0.663	1.00
359_M	363_D	0.661	1.00
284_S	315_T	0.661	1.00
153_Q	156_N	0.660	1.00
347_S	350_K	0.657	1.00
390_T	411_Y	0.657	1.00
62_A	92_A	0.656	1.00
63_C	172_E	0.654	1.00
305_L	320_I	0.653	1.00
256_A	264_C	0.653	1.00
126_A	130_H	0.651	1.00
220_F	224_T	0.651	1.00
66_R	174_F	0.649	1.00
236_Y	277_A	0.648	1.00
210_S	340_N	0.648	1.00
67_R	169_H	0.647	1.00
461_A	523_K	0.647	1.00
206_D	392_R	0.645	1.00
44_D	257_A	0.642	1.00
174_F	177_T	0.640	1.00
217_I	361_P	0.639	1.00
72_P	177_T	0.639	1.00
227_L	268_I	0.639	1.00
165_D	168_N	0.637	1.00
332_F	341_Y	0.635	1.00
49_L	53_E	0.635	1.00
367_V	419_I	0.635	1.00
295_S	323_E	0.634	1.00
267_L	270_K	0.634	1.00
490_R	493_L	0.633	1.00
108_Q	111_E	0.632	1.00
182_D	392_R	0.632	1.00
229_A	279_V	0.631	1.00
514_P	526_L	0.629	1.00
334_M	337_G	0.628	1.00
268_I	276_T	0.628	1.00
123_L	150_R	0.625	1.00
467_D	470_M	0.624	1.00
417_I	428_Q	0.623	1.00
72_P	179_S	0.622	1.00
242_G	277_A	0.622	1.00
269_E	300_A	0.621	1.00
463_V	527_R	0.621	1.00
449_N	453_R	0.621	1.00
130_H	133_F	0.620	1.00
458_I	482_E	0.619	1.00
321_P	327_Q	0.619	1.00
276_T	305_L	0.618	1.00
58_A	61_L	0.617	1.00
80_L	89_T	0.617	1.00
211_V	244_L	0.617	1.00
91_F	244_L	0.616	1.00
118_Q	395_Y	0.615	1.00
80_L	125_I	0.615	1.00
75_T	396_K	0.614	1.00
266_P	297_A	0.614	1.00
64_S	167_I	0.612	1.00
69_G	98_V	0.611	1.00
212_R	248_L	0.610	1.00
196_T	397_S	0.610	1.00
269_E	301_S	0.610	1.00
457_V	478_L	0.609	1.00
85_E	127_D	0.609	1.00
59_D	174_F	0.608	1.00
120_E	395_Y	0.608	1.00
290_L	296_R	0.607	1.00
451_L	493_L	0.606	1.00
252_T	271_H	0.606	1.00
472_E	527_R	0.605	1.00
444_A	462_L	0.605	1.00
63_C	174_F	0.604	1.00
233_A	440_E	0.604	1.00
34_H	250_G	0.604	1.00
316_L	319_R	0.603	1.00
397_S	403_S	0.602	1.00
230_I	277_A	0.602	1.00
186_Y	207_Y	0.602	1.00
391_F	404_A	0.601	1.00
42_V	253_V	0.601	1.00
444_A	523_K	0.601	1.00
36_A	55_N	0.600	1.00
170_P	173_D	0.596	1.00
58_A	62_A	0.595	1.00
66_R	176_A	0.595	1.00
432_K	472_E	0.595	1.00
454_H	457_V	0.594	1.00
478_L	489_V	0.590	1.00
330_Q	353_H	0.590	1.00
80_L	127_D	0.590	1.00
126_A	131_A	0.590	1.00
484_L	489_V	0.589	1.00
79_Q	134_S	0.588	1.00
220_F	251_G	0.587	1.00
30_I	248_L	0.586	1.00
149_I	152_V	0.585	1.00
57_A	167_I	0.585	1.00
374_P	384_M	0.585	1.00
228_C	253_V	0.582	1.00
508_E	529_W	0.582	1.00
63_C	67_R	0.581	1.00
46_E	271_H	0.581	1.00
477_Y	508_E	0.581	1.00
334_M	413_S	0.581	1.00
30_I	208_Y	0.580	1.00
101_V	189_L	0.580	1.00
128_R	153_Q	0.579	1.00
111_E	446_E	0.579	1.00
318_A	321_P	0.576	1.00
450_L	498_I	0.576	1.00
31_L	34_H	0.576	1.00
124_L	149_I	0.576	1.00
457_V	460_A	0.575	1.00
51_Y	251_G	0.574	1.00
187_F	201_P	0.573	1.00
265_F	299_L	0.573	1.00
90_F	243_S	0.572	1.00
225_R	228_C	0.571	1.00
102_L	188_Q	0.571	1.00
355_Q	417_I	0.569	1.00
264_C	268_I	0.569	1.00
99_A	187_F	0.564	1.00
80_L	126_A	0.563	1.00
468_E	471_G	0.563	1.00
212_R	216_E	0.563	1.00
212_R	215_V	0.563	1.00
367_V	383_L	0.562	1.00
312_L	330_Q	0.560	1.00
437_R	470_M	0.560	1.00
118_Q	199_L	0.560	1.00
378_G	418_S	0.559	1.00
210_S	214_S	0.558	1.00
311_R	427_V	0.558	1.00
40_I	225_R	0.556	1.00
305_L	326_C	0.554	1.00
229_A	278_L	0.554	1.00
459_Y	513_L	0.552	1.00
296_R	299_L	0.552	1.00
277_A	308_G	0.552	1.00
120_E	148_S	0.550	1.00
320_I	328_L	0.549	1.00
307_V	328_L	0.549	1.00
65_L	123_L	0.549	1.00
506_R	509_C	0.548	1.00
99_A	395_Y	0.548	1.00
78_V	86_L	0.548	1.00
43_I	46_E	0.548	1.00
60_N	63_C	0.547	1.00
437_R	472_E	0.547	1.00
61_L	163_L	0.546	1.00
107_H	112_L	0.545	1.00
167_I	170_P	0.545	1.00
367_V	381_G	0.545	1.00
374_P	419_I	0.544	1.00
285_L	288_Q	0.542	1.00
124_L	134_S	0.541	1.00
59_D	66_R	0.540	1.00
465_M	477_Y	0.540	1.00
78_V	93_L	0.539	1.00
449_N	452_L	0.538	1.00
183_E	204_H	0.538	1.00
228_C	255_L	0.536	1.00
298_Q	301_S	0.535	1.00
480_V	483_P	0.534	1.00
393_G	398_P	0.533	1.00
28_T	95_K	0.533	1.00
75_T	121_P	0.533	1.00
119_I	199_L	0.532	1.00
447_I	474_S	0.532	1.00
448_E	476_A	0.531	1.00
435_I	464_S	0.531	1.00
237_A	334_M	0.530	1.00
456_A	492_F	0.529	1.00
213_R	217_I	0.529	1.00
57_A	61_L	0.529	1.00
467_D	471_G	0.528	1.00
385_T	390_T	0.528	1.00
308_G	331_V	0.524	1.00
307_V	330_Q	0.523	1.00
81_G	130_H	0.523	1.00
368_A	410_F	0.522	1.00
101_V	115_Y	0.521	1.00
126_A	134_S	0.521	1.00
342_T	355_Q	0.520	1.00
211_V	245_G	0.520	1.00
113_N	146_H	0.519	1.00
42_V	54_L	0.518	1.00
70_I	122_A	0.518	1.00
498_I	502_K	0.518	1.00
341_Y	363_D	0.517	1.00
200_I	335_A	0.515	1.00
318_A	352_I	0.515	1.00
280_P	310_A	0.514	1.00
398_P	401_N	0.514	1.00
308_G	340_N	0.514	1.00
444_A	464_S	0.513	1.00
369_D	372_G	0.513	1.00
152_V	155_L	0.513	1.00
512_S	515_L	0.511	1.00
384_M	406_D	0.511	1.00
103_A	116_A	0.511	1.00
60_N	170_P	0.511	1.00
65_L	98_V	0.509	1.00
368_A	372_G	0.508	1.00
261_A	289_A	0.508	1.00
405_F	411_Y	0.507	1.00
166_A	170_P	0.506	1.00
29_D	178_P	0.506	1.00
287_L	316_L	0.506	1.00
81_G	258_D	0.506	1.00
503_L	507_V	0.506	1.00
32_T	174_F	0.506	1.00
230_I	238_M	0.506	1.00
220_F	245_G	0.504	1.00
433_D	444_A	0.504	1.00
52_R	55_N	0.504	1.00
227_L	264_C	0.503	1.00
99_A	102_L	0.503	1.00
119_I	187_F	0.503	1.00
79_Q	133_F	0.502	1.00
364_E	408_N	0.501	1.00
429_G	444_A	0.500	1.00
460_A	493_L	0.500	1.00
195_G	443_A	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4iz6A	2	0.9981	100	0.117	Contact Map
3tsyA	2	0.7743	100	0.13	Contact Map
1mdbA	1	0.9888	100	0.131	Contact Map
3o83A	1	0.8004	100	0.143	Contact Map
3etcA	2	0.931	100	0.147	Contact Map
3ni2A	1	0.9534	100	0.149	Contact Map
3g7sA	2	0.8825	100	0.153	Contact Map
2d1sA	1	0.959	100	0.155	Contact Map
2vsqA	1	0.9496	100	0.155	Contact Map
1pg4A	1	0.9888	100	0.158	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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